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Conserved domains on  [gi|755556621|ref|XP_011244741|]
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zinc finger protein 811 isoform X2 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
206-355 2.13e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 59.71  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 206 KCKQCGKAFPFPSSLQVHQR--IHTGE--KPYAC--KTCGKTFGHSSSLLRHERIHTGSSPHECKL--CKKTFTRLN--- 274
Cdd:COG5048  291 KSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFSPLLnne 370

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 275 --SLLRHKIIHTGEKPYAC--NQCGKAFSRSASLQRHTRLHTGEKPYVCK--QCGKAFITSTYLQVHERTHTGEKPYVCK 348
Cdd:COG5048  371 ppQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCS 450


                 ....*..
gi 755556621 349 ECGSTFM 355
Cdd:COG5048  451 ILKSFRR 457
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
206-355 2.13e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 59.71  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 206 KCKQCGKAFPFPSSLQVHQR--IHTGE--KPYAC--KTCGKTFGHSSSLLRHERIHTGSSPHECKL--CKKTFTRLN--- 274
Cdd:COG5048  291 KSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFSPLLnne 370

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 275 --SLLRHKIIHTGEKPYAC--NQCGKAFSRSASLQRHTRLHTGEKPYVCK--QCGKAFITSTYLQVHERTHTGEKPYVCK 348
Cdd:COG5048  371 ppQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCS 450


                 ....*..
gi 755556621 349 ECGSTFM 355
Cdd:COG5048  451 ILKSFRR 457
zf-H2C2_2 pfam13465
Zinc-finger double domain;
303-328 6.73e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.73e-04
                          10        20
                  ....*....|....*....|....*.
gi 755556621  303 SLQRHTRLHTGEKPYVCKQCGKAFIT 328
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
206-355 2.13e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 59.71  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 206 KCKQCGKAFPFPSSLQVHQR--IHTGE--KPYAC--KTCGKTFGHSSSLLRHERIHTGSSPHECKL--CKKTFTRLN--- 274
Cdd:COG5048  291 KSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFSPLLnne 370

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 275 --SLLRHKIIHTGEKPYAC--NQCGKAFSRSASLQRHTRLHTGEKPYVCK--QCGKAFITSTYLQVHERTHTGEKPYVCK 348
Cdd:COG5048  371 ppQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCS 450


                 ....*..
gi 755556621 349 ECGSTFM 355
Cdd:COG5048  451 ILKSFRR 457
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
201-531 5.16e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 5.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 201 AKKCSKCKQCGKAFPFPSSLQVHQRIHTGEKPYAC--KTCGKTFGHSSSLLRHERIHTGSSPHEC-KLCKKTFTRLNSLL 277
Cdd:COG5048   30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSS 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 278 RHKIIHTGEKPYACNQCGKAFSRSASLQRHTRLHTGEKPYVCKQC---GKAFITSTYLQV-------------------- 334
Cdd:COG5048  110 LSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnssSVNTPQSNSLHPplpanslskdpssnlsllis 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 335 HERTHTGEKPYVCKECGSTFMLWTQFQKHKIVHS---------------------------------------------- 368
Cdd:COG5048  190 SNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSssslplttnsqlspksllsqspsslsssdssssasesprsslptas 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 369 ----------------GVNPFVCKQCGKAFTRLGTLQIHER--IHTGE--KPYVC--KQCAKAFMSLTQLRRHEIIHSGI 426
Cdd:COG5048  270 sqssspnesdsssekgFSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSI 349

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 427 KPYMCK--QCGKGFL-----CSTTLRSHEKIHSGSNPYVC--SQCEKVVSSESALRKHKMIHTGEKPCVCK--QCGKTFT 495
Cdd:COG5048  350 SPAKEKllNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFN 429

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 755556621 496 HLSSLQYHALMHSGEKPHECKKCGKgFRSLSHLKKH 531
Cdd:COG5048  430 RHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
260-536 1.17e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 260 PHECKLCKKTFTRLNSLLRHKIIHTGEKPYACNQ--CGKAFSRSASLQRHTRLHTGEKPYVCKQCGKAFITSTYLQVHER 337
Cdd:COG5048   33 PDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLSS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 338 THTgekpYVCKECGSTFMLWTQFQKHKIVHSGVNPFV-----CKQCGKAFT----RLGTLQIHERIHTGEKPYV------ 402
Cdd:COG5048  113 SSS----NSNDNNLLSSHSLPPSSRDPQLPDLLSISNlrnnpLPGNNSSSVntpqSNSLHPPLPANSLSKDPSSnlslli 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 403 ---------CKQCAKAFMSLTQLRR---HEIIHSGIKPYMCKQCGKGFLCS------TTLRSHEKIHSGSNPYVCSQCEK 464
Cdd:COG5048  189 ssnvstsipSSSENSPLSSSYSIPSsssDQNLENSSSSLPLTTNSQLSPKSllsqspSSLSSSDSSSSASESPRSSLPTA 268

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755556621 465 VVSSESALRKHKMIHTG-EKPCVCKQCGKTFTHLSSLQYH--ALMHSGE--KPHECKK--CGKGFRSLSHLKKHERTQH 536
Cdd:COG5048  269 SSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
187-477 3.74e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 3.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 187 TSLSSLKRHEQHYHAKKCSKCKQCGKAFPFPSSLQVHQRIHTGEKPYACKTCGKTFGHSSSLLRHERIHTGSSPHECKLC 266
Cdd:COG5048  181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 267 ------KKTFTRLNSLLRHKIIHTG-EKPYACNQCGKAFSRSASLQRHTR--LHTGE--KPYVC--KQCGKAFITSTYLQ 333
Cdd:COG5048  261 prsslpTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALK 340

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 334 VHERTHTGEKPYVCKECGSTfmlwtqfqkHKIVHSGVNPfvckqcgkaftRLGTLQIHERIHTgEKPYVC--KQCAKAFM 411
Cdd:COG5048  341 RHILLHTSISPAKEKLLNSS---------SKFSPLLNNE-----------PPQSLQQYKDLKN-DKKSETlsNSCIRNFK 399

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755556621 412 SLTQLRRHEIIH--SGIKPYMCKQCGKGFLCSTTLRSHEKIHSGSNPYVCSQCEKVVSSESALRKHKM 477
Cdd:COG5048  400 RDSNLSLHIITHlsFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
175-309 3.17e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.15  E-value: 3.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 175 KHHKCKH--CGKACTSLSSLKRHEQHYHAKKCSKCK--QCGKAFPFPS-----SLQVHQRIHTGEKPYAC--KTCGKTFG 243
Cdd:COG5048  320 KPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppQSLQQYKDLKNDKKSETlsNSCIRNFK 399

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755556621 244 HSSSLLRHERIHTGSSPHECK--LCKKTFTRLNSLLRHKIIHTgEKPYACNQCGKAFSRSASLQRHTR 309
Cdd:COG5048  400 RDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT-NHAPLLCSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
303-328 6.73e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.73e-04
                          10        20
                  ....*....|....*....|....*.
gi 755556621  303 SLQRHTRLHTGEKPYVCKQCGKAFIT 328
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
275-300 1.69e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.69e-03
                          10        20
                  ....*....|....*....|....*.
gi 755556621  275 SLLRHKIIHTGEKPYACNQCGKAFSR 300
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 164-251 2.74e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 2.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755556621 164 GQNHERTPA------EEKHHKCK--HCGKACTSLSSLKRHEQHYHakkcskCKQCGKAFPFPSSlqvHQRIHTGEKPYAC 235
Cdd:COG5189  331 GERNIDTPSrmlkvkDGKPYKCPveGCNKKYKNQNGLKYHMLHGH------QNQKLHENPSPEK---MNIFSAKDKPYRC 401

                         90
                 ....*....|....*.
gi 755556621 236 KTCGKTFGHSSSLLRH 251
Cdd:COG5189  402 EVCDKRYKNLNGLKYH 417
zf-H2C2_2 pfam13465
Zinc-finger double domain;
219-242 3.02e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.02e-03
                          10        20
                  ....*....|....*....|....
gi 755556621  219 SLQVHQRIHTGEKPYACKTCGKTF 242
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
331-354 4.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.84e-03
                          10        20
                  ....*....|....*....|....
gi 755556621  331 YLQVHERTHTGEKPYVCKECGSTF 354
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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