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Conserved domains on  [gi|755518871|ref|XP_011239922|]
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protein O-mannosyl-transferase TMTC1 isoform X6 [Mus musculus]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 351-425 1.18e-35

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 128.80  E-value: 1.18e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755518871  351 GGTMPLFSEQDNPASFSPYILTRFLTYSYLLAFNVWLLLAPITLCYDWQVGSIPLVETIWDVRNLATILLAVVMA 425
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
529-655 2.33e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 2.33e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG0457   28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAlqaLGRYEEALEDYDKALELDP 107

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG0457  108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 351-425 1.18e-35

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 128.80  E-value: 1.18e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755518871  351 GGTMPLFSEQDNPASFSPYILTRFLTYSYLLAFNVWLLLAPITLCYDWQVGSIPLVETIWDVRNLATILLAVVMA 425
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
529-655 2.33e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 2.33e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG0457   28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAlqaLGRYEEALEDYDKALELDP 107

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG0457  108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 505-649 4.36e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 4.36e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  505 ASTVLLL---LLFSWKT---VKQNEIWLSREslfrsgvqtlPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHAS 578
Cdd:TIGR02917 736 SQNAIKLhraLLASGNTaeaVKTLEAWLKTH----------PNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAV 805

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755518871  579 ALNNLG--TLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLA 649
Cdd:TIGR02917 806 VLNNLAwlYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLA 878
TPR_12 pfam13424
Tetratricopeptide repeat;
577-636 8.73e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 8.73e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755518871  577 ASALNNLGTL---TKDMAEAKMYYQKALQL--------HPQHNRALFNLGNLLKSQEKTEEAIMLLKESIK 636
Cdd:pfam13424   3 ATALNNLAAVlrrLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALA 73
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 550-661 1.26e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.62  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 550 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHN-RALFNLGNLL---KSQE 622
Cdd:cd24142    7 AEELLDQGNFELALKFLQRALELEPNNVEALELLGEIlleLGDVEEAREVLLRAIELDPDGGyEKYLYLGQLSggeEALQ 86

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 755518871 623 KTEEAIMLLKESIKygpDFADAYSSLASLLAEQSASLTG 661
Cdd:cd24142   87 YYEKGIEILEEELQ---ALQAASAEAEEEAEELKRKLSS 122
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 556-659 8.17e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 42.76  E-value: 8.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  556 QGRNKEAIYHYRTALKLYPRHASALNNLGTLT---KDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEkteeaimllk 632
Cdd:PRK11447  364 ANNLAQAERLYQQARQVDNTDSYAVLGLGDVAmarKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQS---------- 433

                          90       100
                  ....*....|....*....|....*..
gi 755518871  633 esikygPDFADAYssLASLLAEQSASL 659
Cdd:PRK11447  434 ------PEKALAF--IASLSASQRRSI 452
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 577-607 1.36e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.36e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 755518871   577 ASALNNLGTL---TKDMAEAKMYYQKALQLHPQH 607
Cdd:smart00028   1 AEALYNLGNAylkLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 351-425 1.18e-35

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 128.80  E-value: 1.18e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755518871  351 GGTMPLFSEQDNPASFSPYILTRFLTYSYLLAFNVWLLLAPITLCYDWQVGSIPLVETIWDVRNLATILLAVVMA 425
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
529-655 2.33e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 2.33e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG0457   28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAlqaLGRYEEALEDYDKALELDP 107

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG0457  108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
540-655 2.90e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 2.90e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 540 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGN 616
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAylrLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 755518871 617 LLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 540-655 2.82e-23

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 105.08  E-value: 2.82e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 540 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGN 616
Cdd:COG3914  109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAlrrLGRLEEAIAALRRALELDPDNAEALNNLGN 188

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 755518871 617 LLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG3914  189 ALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQA 227
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 539-655 4.65e-22

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 101.22  E-value: 4.65e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 539 LPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLG 615
Cdd:COG3914   74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLllaLGRLEEALAALRRALALNPDFAEAYLNLG 153

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 755518871 616 NLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG3914  154 EALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
529-657 8.21e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 92.38  E-value: 8.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG0457   62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAlleLGRYDEAIEAYERALELDP 141

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQSA 657
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 529-655 1.01e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 92.48  E-value: 1.01e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG2956   96 EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELyleQGDYDEAIEALEKALKLDP 175

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG2956  176 DCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 543-655 1.37e-20

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 88.33  E-value: 1.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 543 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLK 619
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEIllqLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 755518871 620 SQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRAL 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 529-641 6.76e-20

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 86.40  E-value: 6.76e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG4783   24 EALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAllkAGDYDEALALLEKALKLDP 103

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDF 641
Cdd:COG4783  104 EHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 532-654 2.92e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 84.29  E-value: 2.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 532 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHN 608
Cdd:COG4235    6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAllaAGDTEEAEELLERALALDPDNP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 755518871 609 RALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYsSLASLLAE 654
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR-LLEASIAE 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 553-639 1.16e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 83.47  E-value: 1.16e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 553 LKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIM 629
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLysrSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                         90
                 ....*....|
gi 755518871 630 LLKESIKYGP 639
Cdd:COG5010  144 ALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
570-655 5.07e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 83.90  E-value: 5.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 570 LKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYS 646
Cdd:COG0457    1 LELDPDDAEAYNNLGLAyrrLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80


                 ....*....
gi 755518871 647 SLASLLAEQ 655
Cdd:COG0457   81 NLGLALQAL 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
555-640 8.96e-18

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 78.67  E-value: 8.96e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 555 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYyQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLL 631
Cdd:COG3063    4 KLGDLEEAEEYYEKALELDPDNADALNNLGLLlleQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82


                 ....*....
gi 755518871 632 KESIKYGPD 640
Cdd:COG3063   83 ERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 531-655 1.25e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.63  E-value: 1.25e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 531 LFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQH 607
Cdd:COG2956   30 LLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDylkAGLLDRAEELLEKLLELDPDD 109

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 755518871 608 NRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ 157
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
536-667 2.37e-17

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 81.50  E-value: 2.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 536 VQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLG---TLTKDMAEAKMYYQKALQLHPQHNRALF 612
Cdd:COG4785   66 ALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGlayLLLGDYDAALEDFDRALELDPDYAYAYL 145

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 755518871 613 NLGNLLKSQEKTEEAIMLLKESIKYGPDfaDAYSSLASLLAEQSASLTGPKFTLL 667
Cdd:COG4785  146 NRGIALYYLGRYELAIADLEKALELDPN--DPERALWLYLAERKLDPEKALALLL 198
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 540-655 1.67e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.16  E-value: 1.67e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 540 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGN 616
Cdd:COG2956  141 PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELyleQGDYEEAIAALERALEQDPDYLPALPRLAE 220

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 755518871 617 LLKSQEKTEEAIMLLKESIKYGPDfADAYSSLASLLAEQ 655
Cdd:COG2956  221 LYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERK 258
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 529-655 2.38e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.77  E-value: 2.38e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG2956   62 IRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIyeqEGDWEKAIEVLERLLKLGP 141

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG2956  142 ENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 561-655 1.96e-15

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 73.50  E-value: 1.96e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 561 EAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKY 637
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAylrLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90
                 ....*....|....*...
gi 755518871 638 GPDFADAYSSLASLLAEQ 655
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQ 98
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 529-627 7.30e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 78.11  E-value: 7.30e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTKDM---AEAKMYYQKALQLHP 605
Cdd:COG3914  132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLgrlEEAIAAYRRALELDP 211

                         90       100
                 ....*....|....*....|..
gi 755518871 606 QHNRALFNLGNLLKSQEKTEEA 627
Cdd:COG3914  212 DNADAHSNLLFALRQACDWEVY 233
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
529-605 1.69e-14

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 69.43  E-value: 1.69e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIyHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG3063   12 EEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELlleLGDYDEALAYLERALELDP 90
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 547-655 3.68e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.22  E-value: 3.68e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 547 YNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEK 623
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLyrrRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110
                 ....*....|....*....|....*....|..
gi 755518871 624 TEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQE 123
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 529-605 1.02e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 69.22  E-value: 1.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHP 605
Cdd:COG5010   74 LALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALllsLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
588-655 1.62e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 66.73  E-value: 1.62e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755518871 588 KDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMlLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 561-655 2.01e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.49  E-value: 2.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 561 EAIYHYRTALKLYPRHASALNNLGtltkDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPD 640
Cdd:COG3914   69 AAAAALLLLAALLELAALLLQALG----RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD 144

                         90
                 ....*....|....*
gi 755518871 641 FADAYSSLASLLAEQ 655
Cdd:COG3914  145 FAEAYLNLGEALRRL 159
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 505-649 4.36e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 4.36e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  505 ASTVLLL---LLFSWKT---VKQNEIWLSREslfrsgvqtlPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHAS 578
Cdd:TIGR02917 736 SQNAIKLhraLLASGNTaeaVKTLEAWLKTH----------PNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAV 805

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755518871  579 ALNNLG--TLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLA 649
Cdd:TIGR02917 806 VLNNLAwlYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLA 878
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 543-655 1.22e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 66.14  E-value: 1.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 543 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQE 622
Cdd:COG5010   23 LVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSG 102

                         90       100       110
                 ....*....|....*....|....*....|...
gi 755518871 623 KTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG5010  103 DKDEAKEYYEKALALSPDNPNAYSNLAALLLSL 135
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 555-651 1.14e-11

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 61.93  E-value: 1.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 555 DQGRNKEAIYHYRTALKLYPRH---ASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNR---ALFNLGNLLKSQEKTE 625
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAyyaLGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYD 84

                         90       100
                 ....*....|....*....|....*....
gi 755518871 626 EAIMLLKESIKYGPD---FADAYSSLASL 651
Cdd:COG1729   85 KARATLEELIKKYPDseaAKEARARLARL 113
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 540-651 3.40e-11

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 63.90  E-value: 3.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  540 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKAL--QLHPQHNRALFNL 614
Cdd:TIGR02521  62 PDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFlcqQGKYEQAMQQFEQAIedPLYPQPARSLENA 141

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 755518871  615 GNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASL 651
Cdd:TIGR02521 142 GLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAEL 178
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 487-675 2.94e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 2.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  487 GLSKLCAGLSRCGATSLMASTVL--------LLLLFSWktVKQNEIWLSRESLfRSGVQTLPHNAKVHYNYANFLKDQGR 558
Cdd:TIGR02917 404 GISKLSQGDPSEAIADLETAAQLdpelgradLLLILSY--LRSGQFDKALAAA-KKLEKKQPDNASLHNLLGAIYLGKGD 480

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  559 NKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESI 635
Cdd:TIGR02917 481 LAKAREAFEKALSIEPDFFPAAANLARIdiqEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAA 560

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 755518871  636 KYGPdfaDAYsSLASLLAEQSASLTGPK--FTLLDTLASWEK 675
Cdd:TIGR02917 561 ELNP---QEI-EPALALAQYYLGKGQLKkaLAILNEAADAAP 598
TPR_12 pfam13424
Tetratricopeptide repeat;
577-636 8.73e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 8.73e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755518871  577 ASALNNLGTL---TKDMAEAKMYYQKALQL--------HPQHNRALFNLGNLLKSQEKTEEAIMLLKESIK 636
Cdd:pfam13424   3 ATALNNLAAVlrrLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALA 73
TPR_12 pfam13424
Tetratricopeptide repeat;
543-606 9.81e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 9.81e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755518871  543 AKVHYNYANFLKDQGRNKEAIYHYRTALKLY--------PRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQ 606
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLyleLGRYEEALELLERALALAEK 77
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 529-617 1.41e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 50.38  E-value: 1.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 529 ESLFRSGVQTLPHN---AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRH---ASALNNLGTL---TKDMAEAKMYYQK 599
Cdd:COG1729   13 IAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSyleLGDYDKARATLEE 92

                         90       100
                 ....*....|....*....|.
gi 755518871 600 ALQLHPQH---NRALFNLGNL 617
Cdd:COG1729   93 LIKKYPDSeaaKEARARLARL 113
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-658 1.90e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 1.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  556 QGRNKEAIYHYRTALKLYPRHASA--LNNLGTLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKE 633
Cdd:TIGR02917 716 QKDYPAAIQAYRKALKRAPSSQNAikLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQT 795

                          90       100
                  ....*....|....*....|....*
gi 755518871  634 SIKYGPDFADAYSSLASLLAEQSAS 658
Cdd:TIGR02917 796 VVKKAPDNAVVLNNLAWLYLELKDP 820
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 527-634 2.75e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 53.83  E-value: 2.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  527 SRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKL-------YPRHASALNNLGTLTK---DMAEAKMY 596
Cdd:TIGR00990 451 SSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELeketkpmYMNVLPLINKALALFQwkqDFIEAENL 530

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 755518871  597 YQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKES 634
Cdd:TIGR00990 531 CEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERA 568
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 532-654 2.86e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.93  E-value: 2.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  532 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEA---------------------IYHY-------------RTALKLYPRHA 577
Cdd:TIGR02917 522 FEKVLTIDPKNLRAILALAGLYLRTGNEEEAvawlekaaelnpqeiepalalAQYYlgkgqlkkalailNEAADAAPDSP 601

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  578 SALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAE 654
Cdd:TIGR02917 602 EAWLMLGRAqlaAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLA 681
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-652 9.55e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 9.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  556 QGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLK 632
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLllsLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHAD 251

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 755518871  633 ESIKYGP-----------------DFADAYSSLASLL 652
Cdd:TIGR02917 252 ALLKKAPnsplahylkalvdfqkkNYEDARETLQDAL 288
TPR_19 pfam14559
Tetratricopeptide repeat;
588-651 1.07e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 43.34  E-value: 1.07e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755518871  588 KDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASL 651
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 550-661 1.26e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.62  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 550 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHN-RALFNLGNLL---KSQE 622
Cdd:cd24142    7 AEELLDQGNFELALKFLQRALELEPNNVEALELLGEIlleLGDVEEAREVLLRAIELDPDGGyEKYLYLGQLSggeEALQ 86

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 755518871 623 KTEEAIMLLKESIKygpDFADAYSSLASLLAEQSASLTG 661
Cdd:cd24142   87 YYEKGIEILEEELQ---ALQAASAEAEEEAEELKRKLSS 122
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 536-641 1.42e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  536 VQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALF 612
Cdd:TIGR02917 186 LTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATIlieAGEFEEAEKHADALLKKAPNSPLAHY 265

                          90       100
                  ....*....|....*....|....*....
gi 755518871  613 NLGNLLKSQEKTEEAIMLLKESIKYGPDF 641
Cdd:TIGR02917 266 LKALVDFQKKNYEDARETLQDALKSAPEY 294
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-655 2.00e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  556 QGRNKEAIYHYRTALKLYPRHASALNNLG---TLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLK 632
Cdd:TIGR02917 614 AGDLNKAVSSFKKLLALQPDSALALLLLAdayAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAK 693

                          90       100
                  ....*....|....*....|...
gi 755518871  633 ESIKYGPDFADAYSSLASLLAEQ 655
Cdd:TIGR02917 694 SLQKQHPKAALGFELEGDLYLRQ 716
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 540-656 2.56e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 2.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  540 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TKDMAEAKMYYQKALQLHPQHNRALFNLGN 616
Cdd:TIGR02917 496 PDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLylrTGNEEEAVAWLEKAAELNPQEIEPALALAQ 575

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 755518871  617 LLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQS 656
Cdd:TIGR02917 576 YYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAG 615
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 543-575 4.83e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 40.58  E-value: 4.83e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 755518871  543 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPR 575
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR COG0790
TPR repeat [General function prediction only];
566-654 5.12e-05

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 45.30  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 566 YRTALKLYPR-----HASALNNLGTL-------TKDMAEAKMYYQKALQLhpQHNRALFNLGNLLKSQEKTE----EAIM 629
Cdd:COG0790   83 YEKALEWFEKaaeqgDAEAQYNLGLMyeeglgvPQDYAKALEWYEKAAEQ--GDADAQYNLGLLYLNGEGVPkdpaKAAE 160

                         90       100
                 ....*....|....*....|....*
gi 755518871 630 LLKESIKYGpdFADAYSSLASLLAE 654
Cdd:COG0790  161 WYRKAAEQG--DADAQYNLGVLYEN 183
TPR COG0790
TPR repeat [General function prediction only];
542-636 8.14e-05

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 44.53  E-value: 8.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 542 NAKVHYNYANFLKDqGRN-----KEAIYHYRTALKLypRHASALNNLGTL-------TKDMAEAKMYYQKALQLhpQHNR 609
Cdd:COG0790  134 DADAQYNLGLLYLN-GEGvpkdpAKAAEWYRKAAEQ--GDADAQYNLGVLyengrgvPKDPAKALEWYRKAAEQ--GDAD 208

                         90       100       110
                 ....*....|....*....|....*....|.
gi 755518871 610 ALFNLGNLLKSQEKT----EEAIMLLKESIK 636
Cdd:COG0790  209 AQYNLGRLYLNGEGVekdlEKALRWLRKAAE 239
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-655 8.26e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 8.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  556 QGRNKEAIYHYRTALKLYPRHASALNNLGTLT---KDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLK 632
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYAKLGLAQLAlaeNRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYR 217

                          90       100
                  ....*....|....*....|...
gi 755518871  633 ESIKYGPDFADAYSSLASLLAEQ 655
Cdd:TIGR02917 218 KAIALRPNNIAVLLALATILIEA 240
TPR_11 pfam13414
TPR repeat;
615-655 9.50e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.15  E-value: 9.50e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 755518871  615 GNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 541-655 9.73e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 44.90  E-value: 9.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 541 HNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPrHASALNNLGTL-TKDMAEAKMYYQKALQLHPQHNRALFNLGNLLK 619
Cdd:COG3071  191 RDPELAAAYARALIALGDHDEAERLLREALKRQW-DPRLVRLYGRLqGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCL 269

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 755518871 620 SQEKTEEAIMLLKESIKYGPDfADAYSSLASLLAEQ 655
Cdd:COG3071  270 RNQLWGKAREYLEAALALRPS-AEAYAELARLLEQL 304
TPR_11 pfam13414
TPR repeat;
550-584 1.03e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.15  E-value: 1.03e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 755518871  550 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLG 584
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLG 35
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 540-655 2.01e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 2.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  540 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLT---KDMAEAKMYYQKALQLHPQHNRALFNLGN 616
Cdd:TIGR02917 224 PNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDfqkKNYEDARETLQDALKSAPEYLPALLLAGA 303

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 755518871  617 LLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:TIGR02917 304 SEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRL 342
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
546-655 2.02e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 43.72  E-value: 2.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 546 HYNYANFLKDQGRNKEAIYHYRTALK-LYPRHASALNNLG---TLTKDMAEAKMYYQKALQLHPQHNR--ALFNLGNLLK 619
Cdd:COG4700   92 RVRLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAqalFELGRYAEALETLEKLIAKNPDFKSsdAHLLYARALE 171

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 755518871 620 SQEKTEEAIMLLKESIKYGPDFAdAYSSLASLLAEQ 655
Cdd:COG4700  172 ALGDLEAAEAELEALARRYSGPE-ARYRYAKFLARQ 206
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 529-579 2.35e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.53  E-value: 2.35e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASA 579
Cdd:COG4235   71 EELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 532-684 2.48e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 2.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  532 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASA---LNNLGTLTKDMAEAKMYYQKALQLHPQHN 608
Cdd:TIGR02917 624 FKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAqigLAQLLLAAKRTESAKKIAKSLQKQHPKAA 703

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755518871  609 RALFNLGNLLKSQEKTEEAIMLLKESIKYGPDfadaySSLASLLAEqSASLTGPKFTLLDTLASWEKTAciPRDHV 684
Cdd:TIGR02917 704 LGFELEGDLYLRQKDYPAAIQAYRKALKRAPS-----SQNAIKLHR-ALLASGNTAEAVKTLEAWLKTH--PNDAV 771
TPR_1 pfam00515
Tetratricopeptide repeat;
543-576 3.07e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 3.07e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 755518871  543 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRH 576
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 556-659 8.17e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 42.76  E-value: 8.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871  556 QGRNKEAIYHYRTALKLYPRHASALNNLGTLT---KDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEkteeaimllk 632
Cdd:PRK11447  364 ANNLAQAERLYQQARQVDNTDSYAVLGLGDVAmarKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQS---------- 433

                          90       100
                  ....*....|....*....|....*..
gi 755518871  633 esikygPDFADAYssLASLLAEQSASL 659
Cdd:PRK11447  434 ------PEKALAF--IASLSASQRRSI 452
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 577-607 1.36e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.36e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 755518871   577 ASALNNLGTL---TKDMAEAKMYYQKALQLHPQH 607
Cdd:smart00028   1 AEALYNLGNAylkLGDYDEALEYYEKALELDPNN 34
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 537-655 1.44e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 537 QTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLtkDMAEAKMYYQKALQLHPQHNRALFNLGN 616
Cdd:COG3914    9 LAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAA--LLALAAGEAAAAAAALLLLAALLELAAL 86

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 755518871 617 LLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQ 655
Cdd:COG3914   87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLAL 125
TPR_17 pfam13431
Tetratricopeptide repeat;
596-628 1.64e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 36.37  E-value: 1.64e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 755518871  596 YYQKALQLHPQHNRALFNLGNLLKSQEKTEEAI 628
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETAL 33
TPR_1 pfam00515
Tetratricopeptide repeat;
577-607 1.91e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.24  E-value: 1.91e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 755518871  577 ASALNNLGTL---TKDMAEAKMYYQKALQLHPQH 607
Cdd:pfam00515   1 AKALYNLGNAyfkLGKYDEALEYYEKALELNPNN 34
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 550-607 2.20e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.93  E-value: 2.20e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755518871  550 ANFLKDQGRNKEAIYHYRTALKLY---PRHASALNNLG---TLTKDMAEAKMYYQKALQLHPQH 607
Cdd:pfam13432   4 ARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGlaaLRQGRLAEAAAAYRAALRAAPGD 67
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
532-575 3.33e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 3.33e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 755518871 532 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPR 575
Cdd:COG3063   48 LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 569-655 3.90e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 3.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 569 ALKLYPRHASALNNLGTLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSL 648
Cdd:COG5010   15 LLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL 94


                 ....*..
gi 755518871 649 ASLLAEQ 655
Cdd:COG5010   95 ALLYSRS 101
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
532-636 3.92e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.51  E-value: 3.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755518871 532 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGtltkdMAEAKMYYQKALQLHPQHnral 611
Cdd:COG4785  130 FDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLY-----LAERKLDPEKALALLLED---- 200

                         90       100
                 ....*....|....*....|....*
gi 755518871 612 fnLGNLLKSQEKTEEAIMLLKESIK 636
Cdd:COG4785  201 --WATAYLLQGDTEEARELFKLALA 223
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 543-576 4.38e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 4.38e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 755518871   543 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRH 576
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 529-604 7.94e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 7.94e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755518871 529 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRhASALNNLGTL---TKDMAEAKMYYQKALQLH 604
Cdd:COG2956  198 IAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLlerKEGLEAALALLERQLRRH 275
TPR_1 pfam00515
Tetratricopeptide repeat;
609-641 8.53e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.32  E-value: 8.53e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 755518871  609 RALFNLGNLLKSQEKTEEAIMLLKESIKYGPDF 641
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 609-641 8.81e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 8.81e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 755518871   609 RALFNLGNLLKSQEKTEEAIMLLKESIKYGPDF 641
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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