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Conserved domains on  [gi|700383120|ref|XP_009931490|]
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PREDICTED: fibromodulin [Opisthocomus hoazin]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 12183199)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
109-335 2.99e-27

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 111.56  E-value: 2.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQITAIQEgAFDNATELEWLALHNNQITSEKmgkRVFAKLKNLERLYMNNNNLTKMPSPLPR--SLRELH 186
Cdd:COG4886  113 TNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLP---EPLGNLTNLKSLDLSNNQLTDLPEELGNltNLKELD 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 187 LSYNQISKVPSnALEGLENLTALYLSHNYIFEMGASLKGLKSLILADLSYNHLRKVPD--GLPmALEQLYLEYNYINTIP 264
Cdd:COG4886  189 LSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPElgNLT-NLEELDLSNNQLTDLP 266

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120 265 DDYFkvSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYNRLQKIPRVNTNLENLYLQGNQINEFSIS 335
Cdd:COG4886  267 PLAN--LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
LRRNT smart00013
Leucine rich repeat N-terminal domain;
79-113 1.03e-06

Leucine rich repeat N-terminal domain;


:

Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 44.62  E-value: 1.03e-06
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 700383120    79 QCPQECDCPPnfsSAMYCDTRNLRYLPF-VPSRMKY 113
Cdd:smart00013   1 ACPAPCNCSG---TAVDCSGRGLTEVPLdLPPDTTL 33
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
109-335 2.99e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 111.56  E-value: 2.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQITAIQEgAFDNATELEWLALHNNQITSEKmgkRVFAKLKNLERLYMNNNNLTKMPSPLPR--SLRELH 186
Cdd:COG4886  113 TNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLP---EPLGNLTNLKSLDLSNNQLTDLPEELGNltNLKELD 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 187 LSYNQISKVPSnALEGLENLTALYLSHNYIFEMGASLKGLKSLILADLSYNHLRKVPD--GLPmALEQLYLEYNYINTIP 264
Cdd:COG4886  189 LSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPElgNLT-NLEELDLSNNQLTDLP 266

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120 265 DDYFkvSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYNRLQKIPRVNTNLENLYLQGNQINEFSIS 335
Cdd:COG4886  267 PLAN--LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 158-359 3.07e-17

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 79.83  E-value: 3.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 158 LKNLERLYMNNNNLTKMPS-PLPRSLRELHLSYNQISKVPSnaLEGLENLTALYLSHNYIFEMGaSLKGLKSLILADLSY 236
Cdd:cd21340    1 LKRITHLYLNDKNITKIDNlSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 237 NHLRKVpDGL--PMALEQLYLEYNyiNTIPDDYFKVSPkllyvrMSHNSLtnqglstntfnSSSILELDLSYNRLQKI-P 313
Cdd:cd21340   78 NRISVV-EGLenLTNLEELHIENQ--RLPPGEKLTFDP------RSLAAL-----------SNSLRVLNISGNNIDSLeP 137

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 700383120 314 RVN-TNLENLYLQGNQINefSISSFCTVVDVMNYsrLQVLRLDGNEI 359
Cdd:cd21340  138 LAPlRNLEQLDASNNQIS--DLEELLDLLSSWPS--LRELDLTGNPV 180
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
160-354 2.16e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 74.73  E-value: 2.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 160 NLERLYMNNNNLTKMPSPLPRSLRELHLSYNQISKVPSNALEGLENLTalyLSHNYIFEMGASL-KGLKSLilaDLSYNH 238
Cdd:PRK15370 221 NIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLD---LFHNKISCLPENLpEELRYL---SVYDNS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 239 LRKVPDGLPMALEQLYLEYNYINTIPDdyfKVSPKLLYVRMSHNSLTNQGLSTntfnSSSILELDLSYNRLQKIPR-VNT 317
Cdd:PRK15370 295 IRTLPAHLPSGITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLPASL----PPELQVLDVSKNQITVLPEtLPP 367

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 700383120 318 NLENLYLQGNQINEFSiSSFCTVVDVMNYSRLQVLRL 354
Cdd:PRK15370 368 TITTLDVSRNALTNLP-ENLPAALQIMQASRNNLVRL 403
LRR_8 pfam13855
Leucine rich repeat;
160-216 6.94e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 6.94e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120  160 NLERLYMNNNNLTKMP----SPLPrSLRELHLSYNQISKVPSNALEGLENLTALYLSHNYI 216
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDdgafKGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT smart00013
Leucine rich repeat N-terminal domain;
79-113 1.03e-06

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 44.62  E-value: 1.03e-06
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 700383120    79 QCPQECDCPPnfsSAMYCDTRNLRYLPF-VPSRMKY 113
Cdd:smart00013   1 ACPAPCNCSG---TAVDCSGRGLTEVPLdLPPDTTL 33
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 79-109 1.04e-04

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 39.15  E-value: 1.04e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 700383120   79 QCPQECDCPPnfsSAMYCDTRNLRYLPFVPS 109
Cdd:pfam01462   1 ACPVPCHCSA---TVVNCSDRGLTAVPRDLP 28
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
109-335 2.99e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 111.56  E-value: 2.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQITAIQEgAFDNATELEWLALHNNQITSEKmgkRVFAKLKNLERLYMNNNNLTKMPSPLPR--SLRELH 186
Cdd:COG4886  113 TNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLP---EPLGNLTNLKSLDLSNNQLTDLPEELGNltNLKELD 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 187 LSYNQISKVPSnALEGLENLTALYLSHNYIFEMGASLKGLKSLILADLSYNHLRKVPD--GLPmALEQLYLEYNYINTIP 264
Cdd:COG4886  189 LSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPElgNLT-NLEELDLSNNQLTDLP 266

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120 265 DDYFkvSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYNRLQKIPRVNTNLENLYLQGNQINEFSIS 335
Cdd:COG4886  267 PLAN--LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
113-360 6.91e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 84.60  E-value: 6.91e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 113 YVYFQNNQITAIQEGAFDNATELEWLALHNNQITSEKMGKRVFAKLKNLERLYMNNNNLTKMPSPLPrSLRELHLSYNqi 192
Cdd:COG4886   30 LLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLT-NLTELDLSGN-- 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 193 skvpsNALEGLENLTALYLSHNYIFEMGASLKGLKSLILADLSYNHLRKVPDGLPM--ALEQLYLEYNYINTIPDDyFKV 270
Cdd:COG4886  107 -----EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDLPEE-LGN 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 271 SPKLLYVRMSHNSLTNqgLSTNTFNSSSILELDLSYNRLQKIPRV---NTNLENLYLQGNQINEF-SISSFctvvdvmny 346
Cdd:COG4886  181 LTNLKELDLSNNQITD--LPEPLGNLTNLEELDLSGNQLTDLPEPlanLTNLETLDLSNNQLTDLpELGNL--------- 249

                        250
                 ....*....|....
gi 700383120 347 SRLQVLRLDGNEIK 360
Cdd:COG4886  250 TNLEELDLSNNQLT 263
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 158-359 3.07e-17

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 79.83  E-value: 3.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 158 LKNLERLYMNNNNLTKMPS-PLPRSLRELHLSYNQISKVPSnaLEGLENLTALYLSHNYIFEMGaSLKGLKSLILADLSY 236
Cdd:cd21340    1 LKRITHLYLNDKNITKIDNlSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 237 NHLRKVpDGL--PMALEQLYLEYNyiNTIPDDYFKVSPkllyvrMSHNSLtnqglstntfnSSSILELDLSYNRLQKI-P 313
Cdd:cd21340   78 NRISVV-EGLenLTNLEELHIENQ--RLPPGEKLTFDP------RSLAAL-----------SNSLRVLNISGNNIDSLeP 137

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 700383120 314 RVN-TNLENLYLQGNQINefSISSFCTVVDVMNYsrLQVLRLDGNEI 359
Cdd:cd21340  138 LAPlRNLEQLDASNNQIS--DLEELLDLLSSWPS--LRELDLTGNPV 180
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 114-287 1.86e-16

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 77.52  E-value: 1.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 114 VYFQNNQITAIqeGAFDNATELEWLALHNNQITS-EKmgkrvFAKLKNLERLYMNNNNLTKMP--SPLPRsLRELHLSYN 190
Cdd:cd21340    7 LYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKiEN-----LEFLTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 191 QISKVpsNALEGLENLTALYLSHN-------YIFEmGASLKGL-KSLILADLSYNHLRKVPDGLPM-ALEQLYLEYNYIN 261
Cdd:cd21340   79 RISVV--EGLENLTNLEELHIENQrlppgekLTFD-PRSLAALsNSLRVLNISGNNIDSLEPLAPLrNLEQLDASNNQIS 155

                        170       180
                 ....*....|....*....|....*...
gi 700383120 262 TIPD--DYFKVSPKLLYVRMSHNSLTNQ 287
Cdd:cd21340  156 DLEEllDLLSSWPSLRELDLTGNPVCKK 183
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
112-334 7.98e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.44  E-value: 7.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 112 KYVYFQNNQITAIQEgAFDNATELEWLALHNNQITSEKMgkrVFAKLKNLERLYMNNNNLTKMPSPLPR--SLRELHLSY 189
Cdd:COG4886  162 KSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLPE---PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSN 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 190 NQISKVPS--------------------NALEGLENLTALYLSHNYIFEMgaSLKGLKSLILADLSYNHLRkVPDGLPMA 249
Cdd:COG4886  238 NQLTDLPElgnltnleeldlsnnqltdlPPLANLTNLKTLDLSNNQLTDL--KLKELELLLGLNSLLLLLL-LLNLLELL 314

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 250 LEQLYLEYNYINTIPDDYFKVSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYNRLQKIPRVNTNLENLYLQGNQI 329
Cdd:COG4886  315 ILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLL 394


                 ....*
gi 700383120 330 NEFSI 334
Cdd:COG4886  395 TTTAG 399
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
160-354 2.16e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 74.73  E-value: 2.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 160 NLERLYMNNNNLTKMPSPLPRSLRELHLSYNQISKVPSNALEGLENLTalyLSHNYIFEMGASL-KGLKSLilaDLSYNH 238
Cdd:PRK15370 221 NIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLD---LFHNKISCLPENLpEELRYL---SVYDNS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 239 LRKVPDGLPMALEQLYLEYNYINTIPDdyfKVSPKLLYVRMSHNSLTNQGLSTntfnSSSILELDLSYNRLQKIPR-VNT 317
Cdd:PRK15370 295 IRTLPAHLPSGITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLPASL----PPELQVLDVSKNQITVLPEtLPP 367

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 700383120 318 NLENLYLQGNQINEFSiSSFCTVVDVMNYSRLQVLRL 354
Cdd:PRK15370 368 TITTLDVSRNALTNLP-ENLPAALQIMQASRNNLVRL 403
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
109-307 3.52e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 3.52e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQITAIqEGAFDNATELEWLALHNNQITSekmgKRVFAKLKNLERLYMNNNNLTKMPSPLP-RSLRELHL 187
Cdd:COG4886  205 TNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTD----LPELGNLTNLEELDLSNNQLTDLPPLANlTNLKTLDL 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 188 SYNQISKVPSNALEGLENLTALYLSHNYIFEMGASLKGLKSLILADLSYNHLRKVPDGLPMALEQLYLEYNYINTIPDDY 267
Cdd:COG4886  280 SNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLL 359

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 700383120 268 FKVSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYN 307
Cdd:COG4886  360 SLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAG 399
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 123-359 4.52e-11

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 64.04  E-value: 4.52e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 123 AIQEGAFDNATELEWLALHNNQITSEkmGKRVFAKL----KNLERLYMNNNN--------LTKMPSPLPrSLRELHLSYN 190
Cdd:COG5238  170 AISMAKALQNNSVETVYLGCNQIGDE--GIEELAEAltqnTTVTTLWLKRNPigdegaeiLAEALKGNK-SLTTLDLSNN 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 191 QISKVPSNAL-EGLEN---LTALYLSHNYIFEMGA-----SLKGLKSLILADLSYNHLRkvpDGLPMALEQLyLEYNyiN 261
Cdd:COG5238  247 QIGDEGVIALaEALKNnttVETLYLSGNQIGAEGAialakALQGNTTLTSLDLSVNRIG---DEGAIALAEG-LQGN--K 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 262 TIPDdyfkvspkllyVRMSHNSLTNQG---LSTNTFNSSSILELDLSYNR--------LQKIPRVNTNLENLYLQGNQIN 330
Cdd:COG5238  321 TLHT-----------LNLAYNGIGAQGaiaLAKALQENTTLHSLDLSDNQigdegaiaLAKYLEGNTTLRELNLGKNNIG 389

                        250       260
                 ....*....|....*....|....*....
gi 700383120 331 EfsiSSFCTVVDVMNYSRLQVLRLDGNEI 359
Cdd:COG5238  390 K---QGAEALIDALQTNRLHTLILDGNLI 415
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
88-287 7.07e-11

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 63.95  E-value: 7.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120  88 PNFSSAMYCDTRNLRYLP-FVPSRMKYVYFQNNQITAIQEGAFDnatELEWLALHNNQITSekmgkrVFAKL-KNLERLY 165
Cdd:PRK15370 240 PDTIQEMELSINRITELPeRLPSALQSLDLFHNKISCLPENLPE---ELRYLSVYDNSIRT------LPAHLpSGITHLN 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 166 MNNNNLTKMPSPLPRSLRELHLSYNQISKVPSNALEGLENLTalyLSHNYIFEMGASLKglKSLILADLSYNHLRKVPDG 245
Cdd:PRK15370 311 VQSNSLTALPETLPPGLKTLEAGENALTSLPASLPPELQVLD---VSKNQITVLPETLP--PTITTLDVSRNALTNLPEN 385

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 700383120 246 LPMALEQLYLEYNYINTIPDD---YFKVSPKLLYVRMSHNSLTNQ 287
Cdd:PRK15370 386 LPAALQIMQASRNNLVRLPESlphFRGEGPQPTRIIVEYNPFSER 430
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
85-359 5.97e-10

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 60.95  E-value: 5.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120  85 DCPPNFSSAMYCDTRNLRYLPFVPSRMKYVYFQNNQITA---IQEGAFDnatelewLALHNNQITsekmgkRVFAKLKNL 161
Cdd:PRK15387 218 DCLPAHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSlpvLPPGLLE-------LSIFSNPLT------HLPALPSGL 284

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 162 ERLYMNNNNLTKMPSpLPRSLRELHLSYNQISKVPSNALEglenLTALYLSHNYIFEMGASLKGLKSLILADlsyNHLRK 241
Cdd:PRK15387 285 CKLWIFGNQLTSLPV-LPPGLQELSVSDNQLASLPALPSE----LCKLWAYNNQLTSLPTLPSGLQELSVSD---NQLAS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 242 VPDgLPMALEQLYLEYNYINTIPddyfKVSPKLLYVRMSHNSLTNQGLStntfnSSSILELDLSYNRLQKIPRVNTNLEN 321
Cdd:PRK15387 357 LPT-LPSELYKLWAYNNRLTSLP----ALPSGLKELIVSGNRLTSLPVL-----PSELKELMVSGNRLTSLPMLPSGLLS 426

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 700383120 322 LYLQGNQINEFSISsfctvvdVMNYSRLQVLRLDGNEI 359
Cdd:PRK15387 427 LSVYRNQLTRLPES-------LIHLSSETTVNLEGNPL 457
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 152-364 2.89e-09

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 57.75  E-value: 2.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 152 KRVFAKLKNLERLYMNNNNLT--------KMPSPlPRSLRELHLSYNQISKVPSN---ALEGLEN---LTALYLSHNYIF 217
Cdd:cd00116   16 TELLPKLLCLQVLRLEGNTLGeeaakalaSALRP-QPSLKELCLSLNETGRIPRGlqsLLQGLTKgcgLQELDLSDNALG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 218 EMGA-------SLKGLKSLILAD--LSYNHLRKVPDGL---PMALEQLYLEYNYINTIP----DDYFKVSPKLLYVRMSH 281
Cdd:cd00116   95 PDGCgvlesllRSSSLQELKLNNngLGDRGLRLLAKGLkdlPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLAN 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 282 NSLTNQGLST--NTFNSSSILE-LDLSYN--------RLQKIPRVNTNLENLYLQGNQINEFSISSFCTVVDVMNySRLQ 350
Cdd:cd00116  175 NGIGDAGIRAlaEGLKANCNLEvLDLNNNgltdegasALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSPN-ISLL 253

                        250
                 ....*....|....
gi 700383120 351 VLRLDGNEIKRNAV 364
Cdd:cd00116  254 TLSLSCNDITDDGA 267
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 109-359 2.90e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 58.71  E-value: 2.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQITAIQEGAFDNATELEWLALHNNQITSEKmgKRVFAKLKNLERLYMNNNNLT-KMP---SPLPRsLRE 184
Cdd:PLN00113 260 KNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEI--PELVIQLQNLEILHLFSNNFTgKIPvalTSLPR-LQV 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 185 LHLSYNQIS-KVPSNaLEGLENLTALYLSHN----YIFEMGASLKGLKSLILADLSYNHlrKVPDGLPM--ALEQLYLEY 257
Cdd:PLN00113 337 LQLWSNKFSgEIPKN-LGKHNNLTVLDLSTNnltgEIPEGLCSSGNLFKLILFSNSLEG--EIPKSLGAcrSLRRVRLQD 413

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 258 NYIN-TIPDDYFKVsPKLLYVRMSHNSLTNQgLSTNTFNSSSILELDLSYNR-LQKIPRV--NTNLENLYLQGNQINEFS 333
Cdd:PLN00113 414 NSFSgELPSEFTKL-PLVYFLDISNNNLQGR-INSRKWDMPSLQMLSLARNKfFGGLPDSfgSKRLENLDLSRNQFSGAV 491

                        250       260
                 ....*....|....*....|....*.
gi 700383120 334 ISSFctvvdvMNYSRLQVLRLDGNEI 359
Cdd:PLN00113 492 PRKL------GSLSELMQLKLSENKL 511
LRR_8 pfam13855
Leucine rich repeat;
160-216 6.94e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 6.94e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120  160 NLERLYMNNNNLTKMP----SPLPrSLRELHLSYNQISKVPSNALEGLENLTALYLSHNYI 216
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDdgafKGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
180-239 1.69e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.60  E-value: 1.69e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 700383120  180 RSLRELHLSYNQISKVPSNALEGLENLTALYLSHNYI--FEMGAsLKGLKSLILADLSYNHL 239
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLttLSPGA-FSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 109-311 4.97e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 53.90  E-value: 4.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQITAIQEGAFDNAT---ELEWLALHNNQItsEKMGKRVFAK-LK----NLERLYMNNNNLTKMPS---- 176
Cdd:cd00116   81 CGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGL--GDRGLRLLAKgLKdlppALEKLVLGRNRLEGASCeala 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 177 ---PLPRSLRELHLSYNQISK--VPSNALEGLEN--LTALYLSHNYIFEMGAS-----LKGLKSLILADLSYNHLRKVPd 244
Cdd:cd00116  159 kalRANRDLKELNLANNGIGDagIRALAEGLKANcnLEVLDLNNNGLTDEGASalaetLASLKSLEVLNLGDNNLTDAG- 237

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 245 glpmaleqlyleynyINTIPDDYFKVSPKLLYVRMSHNSLTNQG---LSTNTFNSSSILELDLSYNRLQK 311
Cdd:cd00116  238 ---------------AAALASALLSPNISLLTLSLSCNDITDDGakdLAEVLAEKESLLELDLRGNKFGE 292
LRR_8 pfam13855
Leucine rich repeat;
109-171 3.46e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.75  E-value: 3.46e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 700383120  109 SRMKYVYFQNNQITAIQEGAFDNATELEWLALHNNQITSekMGKRVFAKLKNLERLYMNNNNL 171
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 84-226 4.06e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.20  E-value: 4.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120  84 CDCPPNFSSaMYCdTRNLRY----------LPFVPSrMKYVYFQNNQ-----ITAIQEGAFDNaTELEWLALHNNQITSE 148
Cdd:cd00116  133 KDLPPALEK-LVL-GRNRLEgascealakaLRANRD-LKELNLANNGigdagIRALAEGLKAN-CNLEVLDLNNNGLTDE 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 149 KMGK--RVFAKLKNLERLYMNNNNLTK---------MPSPLpRSLRELHLSYNQISKVPSNAL-EGLEN---LTALYLSH 213
Cdd:cd00116  209 GASAlaETLASLKSLEVLNLGDNNLTDagaaalasaLLSPN-ISLLTLSLSCNDITDDGAKDLaEVLAEkesLLELDLRG 287

                        170
                 ....*....|...
gi 700383120 214 NYIFEMGASLKGL 226
Cdd:cd00116  288 NKFGEEGAQLLAE 300
LRRNT smart00013
Leucine rich repeat N-terminal domain;
79-113 1.03e-06

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 44.62  E-value: 1.03e-06
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 700383120    79 QCPQECDCPPnfsSAMYCDTRNLRYLPF-VPSRMKY 113
Cdd:smart00013   1 ACPAPCNCSG---TAVDCSGRGLTEVPLdLPPDTTL 33
LRR_8 pfam13855
Leucine rich repeat;
205-260 8.48e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 8.48e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120  205 NLTALYLSHNYIFEMGA-SLKGLKSLILADLSYNHLRKVP----DGLPmALEQLYLEYNYI 260
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgAFKGLSNLKVLDLSNNLLTTLSpgafSGLP-SLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
250-309 4.59e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 4.59e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700383120  250 LEQLYLEYNYINTIPDDYFKVSPKLLYVRMSHNSLTnqGLSTNTF-NSSSILELDLSYNRL 309
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFsGLPSLRYLDLSGNRL 61
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 79-109 1.04e-04

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 39.15  E-value: 1.04e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 700383120   79 QCPQECDCPPnfsSAMYCDTRNLRYLPFVPS 109
Cdd:pfam01462   1 ACPVPCHCSA---TVVNCSDRGLTAVPRDLP 28
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 159-322 1.18e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.07  E-value: 1.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 159 KNLERLYMNNNNLTkmpSPLPRSLRELHLSYnqISKVPSNALEG--------LENLTALYLSHNYIFEMGASLKGLKSLI 230
Cdd:PLN00113 404 RSLRRVRLQDNSFS---GELPSEFTKLPLVY--FLDISNNNLQGrinsrkwdMPSLQMLSLARNKFFGGLPDSFGSKRLE 478

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 231 LADLSYNHLRK-VPDGLpMALE---QLYLEYNYIN-TIPDDyFKVSPKLLYVRMSHNSLTNQglSTNTFNSSSIL-ELDL 304
Cdd:PLN00113 479 NLDLSRNQFSGaVPRKL-GSLSelmQLKLSENKLSgEIPDE-LSSCKKLVSLDLSHNQLSGQ--IPASFSEMPVLsQLDL 554

                        170
                 ....*....|....*....
gi 700383120 305 SYNRLQ-KIPRVNTNLENL 322
Cdd:PLN00113 555 SQNQLSgEIPKNLGNVESL 573
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 181-214 2.74e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.00  E-value: 2.74e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 700383120  181 SLRELHLSYNQISKVPsnALEGLENLTALYLSHN 214
Cdd:pfam12799   2 NLEVLDLSNNQITDIP--PLAKLPNLETLDLSGN 33
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 106-216 3.81e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 3.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 106 FVPSRMKYVYFQNNQITAIQEGAFDNATELEWLALHNNQITSEKmgKRVFAKLKNLERLYMNNNNLT-KMP---SPLPrS 181
Cdd:PLN00113 472 FGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEI--PDELSSCKKLVSLDLSHNQLSgQIPasfSEMP-V 548

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 700383120 182 LRELHLSYNQIS-KVPSNaLEGLENLTALYLSHNYI 216
Cdd:PLN00113 549 LSQLDLSQNQLSgEIPKN-LGNVESLVQVNISHNHL 583
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 278-361 6.91e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.54  E-value: 6.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 278 RMSHNSLTNQGLSTNTFNSS--SILELDLSYNRLQKIPRVN--TNLENLYLQGNQINEfsISSFCTVVdvmnysRLQVLR 353
Cdd:cd21340    3 RITHLYLNDKNITKIDNLSLckNLKVLYLYDNKITKIENLEflTNLTHLYLQNNQIEK--IENLENLV------NLKKLY 74


                 ....*...
gi 700383120 354 LDGNEIKR 361
Cdd:cd21340   75 LGGNRISV 82
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 109-246 7.76e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 41.76  E-value: 7.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYF----QNNQITAIQEGAFDnATELEWLALHNNQITSEKMGkrvFAKLKNLERLYMNNNNLTKMpspLPRSLR- 183
Cdd:PLN00113 425 TKLPLVYFldisNNNLQGRINSRKWD-MPSLQMLSLARNKFFGGLPD---SFGSKRLENLDLSRNQFSGA---VPRKLGs 497

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 184 -----ELHLSYNQISKVPSNALEGLENLTALYLSHNYIF-EMGASLKGLKSLILADLSYNHLR-KVPDGL 246
Cdd:PLN00113 498 lselmQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNL 567
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 133-171 1.13e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.45  E-value: 1.13e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 700383120  133 TELEWLALHNNQITSEkmgkRVFAKLKNLERLYMNNNNL 171
Cdd:pfam12799   1 PNLEVLDLSNNQITDI----PPLAKLPNLETLDLSGNNK 35
LRR_8 pfam13855
Leucine rich repeat;
272-329 1.80e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 1.80e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 700383120  272 PKLLYVRMSHNSLTNqgLSTNTFNSSSILE-LDLSYNRLQKIPRV----NTNLENLYLQGNQI 329
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKvLDLSNNLLTTLSPGafsgLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
225-284 3.25e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 3.25e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 700383120  225 GLKSLilaDLSYNHLRKVPD----GLPmALEQLYLEYNYINTIPDDYFKVSPKLLYVRMSHNSL 284
Cdd:pfam13855   2 NLRSL---DLSNNRLTSLDDgafkGLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 132-239 5.50e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.06  E-value: 5.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 132 ATELEWLALHNNQITSekMGKRVFAKLKNLERLYMNNNNLT-KMPSPLP--RSLRELHLSYNQIS-KVPSNALEgLENLT 207
Cdd:PLN00113 474 SKRLENLDLSRNQFSG--AVPRKLGSLSELMQLKLSENKLSgEIPDELSscKKLVSLDLSHNQLSgQIPASFSE-MPVLS 550

                         90       100       110
                 ....*....|....*....|....*....|...
gi 700383120 208 ALYLSHNYIF-EMGASLKGLKSLILADLSYNHL 239
Cdd:PLN00113 551 QLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 109-313 6.48e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 38.68  E-value: 6.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 109 SRMKYVYFQNNQIT-AIQEGAFDNateLEWLALHNNQITSE--------------KMGKRVF--------AKLKNLERLY 165
Cdd:PLN00113 118 SSLRYLNLSNNNFTgSIPRGSIPN---LETLDLSNNMLSGEipndigsfsslkvlDLGGNVLvgkipnslTNLTSLEFLT 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 166 MNNNNLT-KMPSPLP--RSLRELHLSYNQISKVPSNALEGLENLTALYLSHN-----------------YIF-------- 217
Cdd:PLN00113 195 LASNQLVgQIPRELGqmKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNnltgpipsslgnlknlqYLFlyqnklsg 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700383120 218 EMGASLKGLKSLILADLSYNHLR-KVPDGLPM--ALEQLYL-EYNYINTIPDDYFKVsPKLLYVRMSHNSLTNqGLSTNT 293
Cdd:PLN00113 275 PIPPSIFSLQKLISLDLSDNSLSgEIPELVIQlqNLEILHLfSNNFTGKIPVALTSL-PRLQVLQLWSNKFSG-EIPKNL 352

                        250       260
                 ....*....|....*....|.
gi 700383120 294 FNSSSILELDLSYNRLQ-KIP 313
Cdd:PLN00113 353 GKHNNLTVLDLSTNNLTgEIP 373
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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