NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|698409740|ref|XP_009708949|]
View 

PREDICTED: LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 3A [Cariama cristata]

Protein Classification

DUF3523 domain-containing ATPase family protein( domain architecture ID 15964341)

DUF3523 domain-containing ATPase family protein associated with various cellular activities (AAA), similar to ATPase AAA-domain protein 3 (ATAD3), a ubiquitously expressed mitochondrial protein

Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18466635|28941010

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
 245-392 5.57e-103

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


:

Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 305.22  E-value: 5.57e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 245 LEARVRDIAIATRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSR 324
Cdd:cd19512    1 LEARVRDIAIATRNTKKNKGLYRNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAIHKVFDWANTSR 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 325 RGLLLFVDEADAFLRKRATEKISEDLRATL*--FFRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNF 392
Cdd:cd19512   81 RGLLLFVDEADAFLRKRSTEKISEDLRAALNafLYRTGEQSNKFMLVLASNQPEQFDWAINDRIDEMVEF 150
ATAD3_N pfam12037
ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal ...
 12-207 3.60e-89

ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal domain of ATPase family AAA domain-containing protein 3 (ATAD3) which is involved in dimerization and interacts with the inner surface of the outer mitochondrial membrane. This domain is found associated with the AAA ATPase domain (pfam00004). ATAD3 is essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organizm and cellular level. It may also play an important role in mitochondrial protein synthesis.


:

Pssm-ID: 463442 [Multi-domain]  Cd Length: 264  Bit Score: 274.17  E-value: 3.60e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   12 AKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMR 91
Cdd:pfam12037  64 AKIKEYEAAQEQLKIERQRVEYEERRKTLQEETKQKQQRAQYQDELARKRYQDQLEAQRRRNEELLRKQEESVAKQEAMR 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   92 -----RATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTAGMLFGEGFRAFVTDWD 166
Cdd:pfam12037 144 iqaqrRQTEEHEAELRRETERAKAEAEAEARAKEERENEDLNLEQLREKANEERETVLESINTAGSHIGGGLRALLTDWD 223

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 698409740  167 KVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVR 207
Cdd:pfam12037 224 KLVAAVGGLTALAAGVYTAKEGTGVAWRYIEARLGKPSLVR 264
 
Name Accession Description Interval E-value
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
 245-392 5.57e-103

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 305.22  E-value: 5.57e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 245 LEARVRDIAIATRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSR 324
Cdd:cd19512    1 LEARVRDIAIATRNTKKNKGLYRNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAIHKVFDWANTSR 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 325 RGLLLFVDEADAFLRKRATEKISEDLRATL*--FFRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNF 392
Cdd:cd19512   81 RGLLLFVDEADAFLRKRSTEKISEDLRAALNafLYRTGEQSNKFMLVLASNQPEQFDWAINDRIDEMVEF 150
ATAD3_N pfam12037
ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal ...
 12-207 3.60e-89

ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal domain of ATPase family AAA domain-containing protein 3 (ATAD3) which is involved in dimerization and interacts with the inner surface of the outer mitochondrial membrane. This domain is found associated with the AAA ATPase domain (pfam00004). ATAD3 is essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organizm and cellular level. It may also play an important role in mitochondrial protein synthesis.


Pssm-ID: 463442 [Multi-domain]  Cd Length: 264  Bit Score: 274.17  E-value: 3.60e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   12 AKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMR 91
Cdd:pfam12037  64 AKIKEYEAAQEQLKIERQRVEYEERRKTLQEETKQKQQRAQYQDELARKRYQDQLEAQRRRNEELLRKQEESVAKQEAMR 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   92 -----RATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTAGMLFGEGFRAFVTDWD 166
Cdd:pfam12037 144 iqaqrRQTEEHEAELRRETERAKAEAEAEARAKEERENEDLNLEQLREKANEERETVLESINTAGSHIGGGLRALLTDWD 223

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 698409740  167 KVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVR 207
Cdd:pfam12037 224 KLVAAVGGLTALAAGVYTAKEGTGVAWRYIEARLGKPSLVR 264
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 236-452 3.04e-23

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 101.53  E-value: 3.04e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 236 LEGVVLSPQLEARVRDIAIATRNTKKNKSLY-----RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVapMGR-EG 309
Cdd:COG0464  156 LDDLGGLEEVKEELRELVALPLKRPELREEYglpppRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLSDL--VSKyVG 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 310 VTA--MHKLFDWANTSRRGLLLFvDEADAFLRKRATEKISEDLRAT---L*ffRTGQHSNKFMLVLASNQPEQFDWAIND 384
Cdd:COG0464  234 ETEknLREVFDKARGLAPCVLFI-DEADALAGKRGEVGDGVGRRVVntlLT--EMEELRSDVVVIAATNRPDLLDPALLR 310

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 698409740 385 RIDEMVNFDLPQLEERERLVRMYFDRhvlkpategkqrlklAQFDYGKKCSEIARLTEGMSGREISQL 452
Cdd:COG0464  311 RFDEIIFFPLPDAEERLEIFRIHLRK---------------RPLDEDVDLEELAEATEGLSGADIRNV 363
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 269-394 1.24e-21

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 90.35  E-value: 1.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGR-EGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRATEKIS 347
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVgESEKRLRELFEAAKKLAPC-VIFIDEIDALAGSRGSGGDS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 698409740  348 EDLR--ATL*FF--RTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNFDL 394
Cdd:pfam00004  80 ESRRvvNQLLTEldGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
256-452 4.52e-12

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 68.52  E-value: 4.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 256 TRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGRE-GVTAMHKLFDWANTSRRgLLLFVDEA 334
Cdd:PRK10733 175 SRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGvGASRVRDMFEQAKKAAP-CIIFIDEI 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 335 DAFLRKRAT------EKISEDLRATL*FFRTGQHSNKFMLVLASNQPEQFDWAI--NDRIDEMVNFDLPQLEERERLVRM 406
Cdd:PRK10733 254 DAVGRQRGAglggghDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALlrPGRFDRQVVVGLPDVRGREQILKV 333

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 698409740 407 YFDRHVLKPATEGkqrlklaqfdygkkcSEIARLTEGMSGREISQL 452
Cdd:PRK10733 334 HMRRVPLAPDIDA---------------AIIARGTPGFSGADLANL 364
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 267-452 4.24e-09

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 59.15  E-value: 4.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDV-APMGREGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRAT-- 343
Cdd:TIGR01243 488 KGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEIlSKWVGESEKAIREIFRKARQAAPA-IIFFDEIDAIAPARGArf 566

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  344 -EKISEDLRATL*FFRTGQHSNKFMLVL-ASNQPEQFDwaindridemvnfdlPQLEERERlvrmyFDRHVLKPATEGKQ 421
Cdd:TIGR01243 567 dTSVTDRIVNQLLTEMDGIQELSNVVVIaATNRPDILD---------------PALLRPGR-----FDRLILVPPPDEEA 626

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 698409740  422 RLKLAQFDYGK-------KCSEIARLTEGMSGREISQL 452
Cdd:TIGR01243 627 RKEIFKIHTRSmplaedvDLEELAEMTEGYTGADIEAV 664
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 267-395 1.34e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.92  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   267 RNILMYGPPGTGKTLFAKKLAVHSG------------------MDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGlL 328
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGppgggviyidgedileevLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD-V 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 698409740   329 LFVDEADAFLRKRATEKISEDLRATL*FFRtgQHSNKFMLVLASNQPEQFDWA-INDRIDEMVNFDLP 395
Cdd:smart00382  82 LILDEITSLLDAEQEALLLLLEELRLLLLL--KSEKNLTVILTTNDEKDLGPAlLRRRFDRRIVLLLI 147
PTZ00121 PTZ00121
MAEBL; Provisional
 13-150 2.92e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   13 KLKEYEAAIEQLKNEQIRvQAEERRKTlSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRK--QEESVQKQEAM 90
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELK-KAEELKKA-EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKlyEEEKKMKAEEA 1612

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 698409740   91 RRATVEREM--ELRHKNEMLRVEAEARARAKAERENADIIR---EQIRLKAAEHRQTVLESLKTA 150
Cdd:PTZ00121 1613 KKAEEAKIKaeELKKAEEEKKKVEQLKKKEAEEKKKAEELKkaeEENKIKAAEEAKKAEEDKKKA 1677
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 12-150 3.80e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.92  E-value: 3.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  12 AKLKEYEAAIEQLKNEQIRVQAEERRKTLSEetkqHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMR 91
Cdd:COG1196  260 AELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  92 RATVER-EMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTA 150
Cdd:COG1196  336 EEELEElEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
 
Name Accession Description Interval E-value
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
 245-392 5.57e-103

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 305.22  E-value: 5.57e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 245 LEARVRDIAIATRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSR 324
Cdd:cd19512    1 LEARVRDIAIATRNTKKNKGLYRNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAIHKVFDWANTSR 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 325 RGLLLFVDEADAFLRKRATEKISEDLRATL*--FFRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNF 392
Cdd:cd19512   81 RGLLLFVDEADAFLRKRSTEKISEDLRAALNafLYRTGEQSNKFMLVLASNQPEQFDWAINDRIDEMVEF 150
ATAD3_N pfam12037
ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal ...
 12-207 3.60e-89

ATPase family AAA domain-containing protein 3, N-terminal; This is the conserved N-terminal domain of ATPase family AAA domain-containing protein 3 (ATAD3) which is involved in dimerization and interacts with the inner surface of the outer mitochondrial membrane. This domain is found associated with the AAA ATPase domain (pfam00004). ATAD3 is essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organizm and cellular level. It may also play an important role in mitochondrial protein synthesis.


Pssm-ID: 463442 [Multi-domain]  Cd Length: 264  Bit Score: 274.17  E-value: 3.60e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   12 AKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMR 91
Cdd:pfam12037  64 AKIKEYEAAQEQLKIERQRVEYEERRKTLQEETKQKQQRAQYQDELARKRYQDQLEAQRRRNEELLRKQEESVAKQEAMR 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   92 -----RATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTAGMLFGEGFRAFVTDWD 166
Cdd:pfam12037 144 iqaqrRQTEEHEAELRRETERAKAEAEAEARAKEERENEDLNLEQLREKANEERETVLESINTAGSHIGGGLRALLTDWD 223

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 698409740  167 KVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVR 207
Cdd:pfam12037 224 KLVAAVGGLTALAAGVYTAKEGTGVAWRYIEARLGKPSLVR 264
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 245-392 3.05e-32

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 120.85  E-value: 3.05e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 245 LEARVRDIAIATRNTKKNKS----LYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGR-EGVTAMHKLFDW 319
Cdd:cd19481    1 LKASLREAVEAPRRGSRLRRyglgLPKGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVgESEKNLRKIFER 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 698409740 320 ANTSRRGLLLFvDEADAFLRKRATEKISEDLRATL*FFRT----GQHSNKFMLVLASNQPEQFDWAIND--RIDEMVNF 392
Cdd:cd19481   81 ARRLAPCILFI-DEIDAIGRKRDSSGESGELRRVLNQLLTeldgVNSRSKVLVIAATNRPDLLDPALLRpgRFDEVIEF 158
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 236-452 3.04e-23

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 101.53  E-value: 3.04e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 236 LEGVVLSPQLEARVRDIAIATRNTKKNKSLY-----RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVapMGR-EG 309
Cdd:COG0464  156 LDDLGGLEEVKEELRELVALPLKRPELREEYglpppRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLSDL--VSKyVG 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 310 VTA--MHKLFDWANTSRRGLLLFvDEADAFLRKRATEKISEDLRAT---L*ffRTGQHSNKFMLVLASNQPEQFDWAIND 384
Cdd:COG0464  234 ETEknLREVFDKARGLAPCVLFI-DEADALAGKRGEVGDGVGRRVVntlLT--EMEELRSDVVVIAATNRPDLLDPALLR 310

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 698409740 385 RIDEMVNFDLPQLEERERLVRMYFDRhvlkpategkqrlklAQFDYGKKCSEIARLTEGMSGREISQL 452
Cdd:COG0464  311 RFDEIIFFPLPDAEERLEIFRIHLRK---------------RPLDEDVDLEELAEATEGLSGADIRNV 363
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
236-452 5.09e-22

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 94.95  E-value: 5.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 236 LEGVVLSPQLEARVRDIAIATRNTKK----NKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVapMGR---E 308
Cdd:COG1223    1 LDDVVGQEEAKKKLKLIIKELRRRENlrkfGLWPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSL--IGSylgE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 309 GVTAMHKLFDWANtsRRGLLLFVDEADAFLRKRATEKISEDLRATL*FFRT--GQHSNKFMLVLASNQPEQFDWAINDRI 386
Cdd:COG1223   79 TARNLRKLFDFAR--RAPCVIFFDEFDAIAKDRGDQNDVGEVKRVVNALLQelDGLPSGSVVIAATNHPELLDSALWRRF 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 698409740 387 DEMVNFDLPQLEERERLVRMYFDRHVLKPATEGKqrlklaqfdygkkcsEIARLTEGMSGREISQL 452
Cdd:COG1223  157 DEVIEFPLPDKEERKEILELNLKKFPLPFELDLK---------------KLAKKLEGLSGADIEKV 207
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 269-394 1.24e-21

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 90.35  E-value: 1.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGR-EGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRATEKIS 347
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVgESEKRLRELFEAAKKLAPC-VIFIDEIDALAGSRGSGGDS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 698409740  348 EDLR--ATL*FF--RTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNFDL 394
Cdd:pfam00004  80 ESRRvvNQLLTEldGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 269-489 4.89e-18

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 85.06  E-value: 4.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPM--GrEGVTAMHKLFDWANTSRRGLLLFvDEADAFLRKRATEKI 346
Cdd:COG1222  115 VLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSKyiG-EGARNVREVFELAREKAPSIIFI-DEIDAIAARRTDDGT 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 347 SEDLRATL*FFRT---GQHSNKFMLVL-ASNQPEQFDWAI--NDRIDEMVNFDLPQLEERERLVRMYFdrhvlkpategk 420
Cdd:COG1222  193 SGEVQRTVNQLLAeldGFESRGDVLIIaATNRPDLLDPALlrPGRFDRVIEVPLPDEEAREEILKIHL------------ 260

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 421 QRLKLA-QFDYgkkcSEIARLTEGMSGREISQLAVAWQAAAYASEDGVLTEamidARVADAVQQHKQKME 489
Cdd:COG1222  261 RDMPLAdDVDL----DKLAKLTEGFSGADLKAIVTEAGMFAIREGRDTVTM----EDLEKAIEKVKKKTE 322
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
256-452 4.52e-12

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 68.52  E-value: 4.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 256 TRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGRE-GVTAMHKLFDWANTSRRgLLLFVDEA 334
Cdd:PRK10733 175 SRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGvGASRVRDMFEQAKKAAP-CIIFIDEI 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 335 DAFLRKRAT------EKISEDLRATL*FFRTGQHSNKFMLVLASNQPEQFDWAI--NDRIDEMVNFDLPQLEERERLVRM 406
Cdd:PRK10733 254 DAVGRQRGAglggghDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALlrPGRFDRQVVVGLPDVRGREQILKV 333

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 698409740 407 YFDRHVLKPATEGkqrlklaqfdygkkcSEIARLTEGMSGREISQL 452
Cdd:PRK10733 334 HMRRVPLAPDIDA---------------AIIARGTPGFSGADLANL 364
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 266-394 1.35e-10

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 59.47  E-value: 1.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 266 YRNILMYGPPGTGKTLFAKKLA---VHSGMDYAIMTGGDVAPMGREGVTAMHKLFDW---ANTSRRGLLLFVDEADAFLR 339
Cdd:cd00009   19 PKNLLLYGPPGTGKTTLARAIAnelFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLlfeLAEKAKPGVLFIDEIDSLSR 98

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 698409740 340 kratEKISEDLRATL*FFRTGQHSNKFMLVLASNQPE--QFDWAINDRIDEMVNFDL 394
Cdd:cd00009   99 ----GAQNALLRVLETLNDLRIDRENVRVIGATNRPLlgDLDRALYDRLDIRIVIPL 151
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 262-385 5.46e-10

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 58.13  E-value: 5.46e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 262 NKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVA--PMGrEGVTAMHKLFDWANtSRRGLLLFVDEADAFLR 339
Cdd:cd19509   28 LRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVskWVG-ESEKIVRALFALAR-ELQPSIIFIDEIDSLLS 105

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 698409740 340 KRATEKISEDLRATL*FFR-----TGQHSNKFMLVLASNQPEQFDWAINDR 385
Cdd:cd19509  106 ERGSGEHEASRRVKTEFLVqmdgvLNKPEDRVLVLGATNRPWELDEAFLRR 156
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
 267-386 9.77e-10

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 57.43  E-value: 9.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMtggDVAPMGREGVTAMHKLFDWANTSRRGL---LLFVDEADAFLRKR-- 341
Cdd:cd19520   36 KGVLLYGPPGCGKTMLAKATAKEAGARFINL---QVSSLTDKWYGESQKLVAAVFSLASKLqpsIIFIDEIDSFLRQRss 112

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 698409740 342 ----ATEKISEDLRATL*FFRTGQHSnKFMLVLASNQPEQFDWAINDRI 386
Cdd:cd19520  113 tdheATAMMKAEFMSLWDGLSTDGNC-RVIVMGATNRPQDLDEAILRRM 160
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 267-390 1.15e-09

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 57.29  E-value: 1.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPM--GrEGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRATE 344
Cdd:cd19511   28 KGVLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKyvG-ESERAVREIFQKARQAAPC-IIFFDEIDSLAPRRGQS 105

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 698409740 345 K---ISEDLRATL*FFRTGQHSNKFMLVL-ASNQPEQFDWAI--NDRIDEMV 390
Cdd:cd19511  106 DssgVTDRVVSQLLTELDGIESLKGVVVIaATNRPDMIDPALlrPGRLDKLI 157
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 267-452 4.24e-09

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 59.15  E-value: 4.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDV-APMGREGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRAT-- 343
Cdd:TIGR01243 488 KGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEIlSKWVGESEKAIREIFRKARQAAPA-IIFFDEIDAIAPARGArf 566

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  344 -EKISEDLRATL*FFRTGQHSNKFMLVL-ASNQPEQFDwaindridemvnfdlPQLEERERlvrmyFDRHVLKPATEGKQ 421
Cdd:TIGR01243 567 dTSVTDRIVNQLLTEMDGIQELSNVVVIaATNRPDILD---------------PALLRPGR-----FDRLILVPPPDEEA 626

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 698409740  422 RLKLAQFDYGK-------KCSEIARLTEGMSGREISQL 452
Cdd:TIGR01243 627 RKEIFKIHTRSmplaedvDLEELAEMTEGYTGADIEAV 664
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 267-395 1.34e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.92  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   267 RNILMYGPPGTGKTLFAKKLAVHSG------------------MDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGlL 328
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGppgggviyidgedileevLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD-V 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 698409740   329 LFVDEADAFLRKRATEKISEDLRATL*FFRtgQHSNKFMLVLASNQPEQFDWA-INDRIDEMVNFDLP 395
Cdd:smart00382  82 LILDEITSLLDAEQEALLLLLEELRLLLLL--KSEKNLTVILTTNDEKDLGPAlLRRRFDRRIVLLLI 147
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
 267-382 2.04e-08

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 53.59  E-value: 2.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDV-APMGREGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKR--AT 343
Cdd:cd19519   35 RGILLYGPPGTGKTLIARAVANETGAFFFLINGPEImSKLAGESESNLRKAFEEAEKNAPA-IIFIDEIDAIAPKRekTH 113

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 698409740 344 EKISEDLRATL*FFRTGQHSNKFMLVL-ASNQPEQFDWAI 382
Cdd:cd19519  114 GEVERRIVSQLLTLMDGLKQRAHVIVMaATNRPNSIDPAL 153
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
 259-390 2.23e-08

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 53.67  E-value: 2.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 259 TKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPM--GrEGVTAMHKLFDWANTSRRgLLLFVDEADA 336
Cdd:cd19528   20 LKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMwfG-ESEANVRDIFDKARAAAP-CVLFFDELDS 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 698409740 337 FLRKR---------ATEKISEDLRATL*ffrTGQHSNKFMLVL-ASNQPEQFDWAI--NDRIDEMV 390
Cdd:cd19528   98 IAKARggnigdaggAADRVINQILTEM----DGMNTKKNVFIIgATNRPDIIDPAIlrPGRLDQLI 159
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 267-382 2.37e-08

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 53.45  E-value: 2.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVapMGR---EGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRAT 343
Cdd:cd19503   35 RGVLLHGPPGTGKTLLARAVANEAGANFLSISGPSI--VSKylgESEKNLREIFEEARSHAPS-IIFIDEIDALAPKREE 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 698409740 344 --EKISEDLRATL*FFRTGQHSNKFMLVLAS-NQPEQFDWAI 382
Cdd:cd19503  112 dqREVERRVVAQLLTLMDGMSSRGKVVVIAAtNRPDAIDPAL 153
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 267-440 2.64e-08

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 56.45  E-value: 2.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVapMGR---EGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKR-- 341
Cdd:TIGR01243 213 KGVLLYGPPGTGKTLLAKAVANEAGAYFISINGPEI--MSKyygESEERLREIFKEAEENAPS-IIFIDEIDAIAPKRee 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  342 ATEKISEDLRATL*FFRTG-QHSNKFMLVLASNQPEQFDWAIN--DRIDEMVNFDLPQLEERERLVRMYFDRhvlKPATE 418
Cdd:TIGR01243 290 VTGEVEKRVVAQLLTLMDGlKGRGRVIVIGATNRPDALDPALRrpGRFDREIVIRVPDKRARKEILKVHTRN---MPLAE 366

                         170       180
                  ....*....|....*....|..
gi 698409740  419 GKQRLKLAQFDYGKKCSEIARL 440
Cdd:TIGR01243 367 DVDLDKLAEVTHGFVGADLAAL 388
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
 262-390 3.35e-08

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 53.33  E-value: 3.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 262 NKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAP--MGrEGVTAMHKLFDWANTSRRGlLLFVDEADAFLR 339
Cdd:cd19521   36 NRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSkwMG-ESEKLVKQLFAMARENKPS-IIFIDEVDSLCG 113

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 698409740 340 KRATEKISEDLRATL*FFRTGQ---HSNKFMLVL-ASNQPEQFDWAINDRIDEMV 390
Cdd:cd19521  114 TRGEGESEASRRIKTELLVQMNgvgNDSQGVLVLgATNIPWQLDSAIRRRFEKRI 168
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
 267-382 4.34e-08

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 53.01  E-value: 4.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMgREGVTA--MHKLFDWANTSRRgLLLFVDEADAFLRKR-AT 343
Cdd:cd19501   38 KGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEM-FVGVGAsrVRDLFEQAKKNAP-CIVFIDEIDAVGRKRgAG 115

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 698409740 344 EKISEDLR-ATL*FFRT---GQHSNKFMLVL-ASNQPEQFDWAI 382
Cdd:cd19501  116 LGGGHDEReQTLNQLLVemdGFESNTGVIVIaATNRPDVLDPAL 159
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 269-390 4.81e-08

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 52.49  E-value: 4.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPM--GrEGVTAMHKLFDWANTSRRGLLLFvDEADAFLRKRATEKI 346
Cdd:cd19530   33 VLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKyvG-ESERAVRQVFQRARASAPCVIFF-DEVDALVPKRGDGGS 110

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 698409740 347 SEDLRATL*FFRT---GQHSNKFMLVLASNQPEQFDWAI--NDRIDEMV 390
Cdd:cd19530  111 WASERVVNQLLTEmdgLEERSNVFVIAATNRPDIIDPAMlrPGRLDKTL 159
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
 267-382 6.70e-08

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 52.11  E-value: 6.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAP--MGrEGVTAMHKLFDWANTSRRgLLLFVDEADAFLRKRA-- 342
Cdd:cd19529   28 KGILLYGPPGTGKTLLAKAVATESNANFISVKGPELLSkwVG-ESEKAIREIFRKARQVAP-CVIFFDEIDSIAPRRGtt 105

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 698409740 343 -----TEKISEDLRATL*FFrtgQHSNKFMLVLASNQPEQFDWAI 382
Cdd:cd19529  106 gdsgvTERVVNQLLTELDGL---EEMNGVVVIAATNRPDIIDPAL 147
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
 266-390 7.46e-08

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 52.29  E-value: 7.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 266 YRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGR-EGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKRATE 344
Cdd:cd19522   33 WKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRgESEKLVRLLFEMARFYAPT-TIFIDEIDSICSRRGTS 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 698409740 345 ---KISEDLRATL*F-------FRTGQHSNKFMLVL-ASNQPEQFDWAINDRIDEMV 390
Cdd:cd19522  112 eehEASRRVKSELLVqmdgvggASENDDPSKMVMVLaATNFPWDIDEALRRRLEKRI 168
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
 232-386 1.01e-07

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 52.30  E-value: 1.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 232 AQDALEGVVLSPQLEArvrDIAIATRNTKKNkslyrnILMYGPPGTGKTLFAKKLAVHSGMD-YAIMTGGDVAPMGREGV 310
Cdd:cd19525   30 AKKTIKEIVVWPMLRP---DIFTGLRGPPKG------ILLFGPPGTGKTLIGKCIASQSGATfFSISASSLTSKWVGEGE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 311 TAMHKLFDWANTSRRGlLLFVDEADAFLRKRATEKISEDLRATL*FF-----RTGQHSNKFMLVLASNQPEQFDWAINDR 385
Cdd:cd19525  101 KMVRALFSVARCKQPA-VIFIDEIDSLLSQRGEGEHESSRRIKTEFLvqldgATTSSEDRILVVGATNRPQEIDEAARRR 179


                 .
gi 698409740 386 I 386
Cdd:cd19525  180 L 180
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 267-392 1.33e-07

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 51.57  E-value: 1.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGD-VAPMGREGVTAMHKLFDWANTsRRGLLLFVDEADAFLRKRATEK 345
Cdd:cd19502   38 KGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSElVQKYIGEGARLVRELFEMARE-KAPSIIFIDEIDAIGAKRFDSG 116

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 698409740 346 ISED---------LRATL*FFRTgqhSNKFMLVLASNQPEQFDWAI--NDRIDEMVNF 392
Cdd:cd19502  117 TGGDrevqrtmleLLNQLDGFDP---RGNIKVIMATNRPDILDPALlrPGRFDRKIEF 171
ftsH CHL00176
cell division protein; Validated
 269-452 3.28e-07

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 53.13  E-value: 3.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMgREGVTA--MHKLFDWANtSRRGLLLFVDEADAFLRKRATE-K 345
Cdd:CHL00176 219 VLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEM-FVGVGAarVRDLFKKAK-ENSPCIVFIDEIDAVGRQRGAGiG 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 346 ISEDLR-ATL*FFRT---GQHSNKFMLVL-ASNQPEQFDWAI--NDRIDEMVNFDLPQLEERERLVRMYFDRHVLKPATE 418
Cdd:CHL00176 297 GGNDEReQTLNQLLTemdGFKGNKGVIVIaATNRVDILDAALlrPGRFDRQITVSLPDREGRLDILKVHARNKKLSPDVS 376

                        170       180       190
                 ....*....|....*....|....*....|....
gi 698409740 419 GKQrlklaqfdygkkcseIARLTEGMSGREISQL 452
Cdd:CHL00176 377 LEL---------------IARRTPGFSGADLANL 395
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 269-452 1.12e-06

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 50.99  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTG--------GDVAPMGREgvtamhkLFDWANtSRRGLLLFVDEADAFLRK 340
Cdd:PRK03992 168 VLLYGPPGTGKTLLAKAVAHETNATFIRVVGselvqkfiGEGARLVRE-------LFELAR-EKAPSIIFIDEIDAIAAK 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 341 RATEKISED---------LRATL*FFRTgqhSNKFMLVLASNQPEQFDWAI--NDRIDEMVNFDLPQLEERERlvrmyfd 409
Cdd:PRK03992 240 RTDSGTSGDrevqrtlmqLLAEMDGFDP---RGNVKIIAATNRIDILDPAIlrPGRFDRIIEVPLPDEEGRLE------- 309

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 698409740 410 rhVLKPATegkQRLKLAQ-FDYgkkcSEIARLTEGMSGREISQL 452
Cdd:PRK03992 310 --ILKIHT---RKMNLADdVDL----EELAELTEGASGADLKAI 344
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 267-382 1.58e-06

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 48.17  E-value: 1.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMD-YAIMTGGDVAPMGREGVTAMHKLFDWAnTSRRGLLLFVDEADAFLRKRAT-- 343
Cdd:cd19518   35 RGVLLHGPPGCGKTMLANAIAGELKVPfLKISATEIVSGVSGESEEKIRELFDQA-ISNAPCIVFIDEIDAITPKRESaq 113

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 698409740 344 ----EKISEDLRATL*FFRTGQHSNKFMLVL-ASNQPEQFDWAI 382
Cdd:cd19518  114 remeRRIVSQLLTCMDELNNEKTAGGPVLVIgATNRPDSLDPAL 157
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
 267-392 4.43e-06

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 47.12  E-value: 4.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDyaimtGGDVAPMGREGVTAMHK-----------LFDWANTSRRGLLLFvDEAD 335
Cdd:cd19517   35 RGVLFHGPPGTGKTLMARALAAECSKG-----GQKVSFFMRKGADCLSKwvgeaerqlrlLFEEAYRMQPSIIFF-DEID 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 698409740 336 --AFLRKRATEKISEDLRATL*FFRTGQHSNKFMLVL-ASNQPEQFDWAIN--DRIDEMVNF 392
Cdd:cd19517  109 glAPVRSSKQEQIHASIVSTLLALMDGLDNRGQVVVIgATNRPDALDPALRrpGRFDREFYF 170
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
 267-390 8.12e-06

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 46.00  E-value: 8.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDY-----AIMTGGDVApmgrEGVTAMHKLFDWAnTSRRGLLLFVDEADAFLRKR 341
Cdd:cd19524   34 RGLLLFGPPGNGKTMLAKAVAAESNATFfnisaASLTSKYVG----EGEKLVRALFAVA-RELQPSIIFIDEVDSLLSER 108

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 698409740 342 AT--EKISEDLRATL*FFRTGQHSNKFMLVL---ASNQPEQFDWAINDRIDEMV 390
Cdd:cd19524  109 SEgeHEASRRLKTEFLIEFDGVQSNGDDRVLvmgATNRPQELDDAVLRRFTKRV 162
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
 267-404 8.14e-06

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 48.22  E-value: 8.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGD-VAPMGREGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKR---- 341
Cdd:PTZ00454 180 RGVLLYGPPGTGKTMLAKAVAHHTTATFIRVVGSEfVQKYLGEGPRMVRDVFRLARENAPS-IIFIDEVDSIATKRfdaq 258

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 698409740 342 --ATEKISEDLRATL*FFRTGQHSNKFMLVLASNQPEQFDWAI--NDRIDEMVNFDLPQLEEReRLV 404
Cdd:PTZ00454 259 tgADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALlrPGRLDRKIEFPLPDRRQK-RLI 324
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
 269-390 8.80e-06

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 45.97  E-value: 8.80e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 269 ILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMG-REGVTAMHKLFDWANTSRRGLLLFvDEADAFLRKRAT---- 343
Cdd:cd19527   29 ILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYiGESEANVREVFQKARDAKPCVIFF-DELDSLAPSRGNsgds 107

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 698409740 344 ----EKISEDLRATL*FFRTGqhSNKFMLVLASNQPEQFDWAI--NDRIDEMV 390
Cdd:cd19527  108 ggvmDRVVSQLLAELDGMSSS--GQDVFVIGATNRPDLLDPALlrPGRFDKLL 158
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
 264-385 3.27e-05

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 44.49  E-value: 3.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 264 SLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTG-GDVAPMGREGVTAMHKLFDWANtSRRGLLLFVDEADAFLRKRA 342
Cdd:cd19523   31 RLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGsTLVAKWAGEGEKILQASFLAAR-CRQPSVLFISDLDALLSSQD 109

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 698409740 343 TE-----KISEDLRATL*FFrTGQHSNKFMLVLASNQPEQFDWAINDR 385
Cdd:cd19523  110 DEaspvgRLQVELLAQLDGV-LGSGEDGVLVVCTTSKPEEIDESLRRY 156
PTZ00121 PTZ00121
MAEBL; Provisional
 13-150 2.92e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   13 KLKEYEAAIEQLKNEQIRvQAEERRKTlSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRK--QEESVQKQEAM 90
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELK-KAEELKKA-EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKlyEEEKKMKAEEA 1612

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 698409740   91 RRATVEREM--ELRHKNEMLRVEAEARARAKAERENADIIR---EQIRLKAAEHRQTVLESLKTA 150
Cdd:PTZ00121 1613 KKAEEAKIKaeELKKAEEEKKKVEQLKKKEAEEKKKAEELKkaeEENKIKAAEEAKKAEEDKKKA 1677
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
 268-341 3.24e-04

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 41.26  E-value: 3.24e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 698409740 268 NILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAP----MGREGVtamHKLFDWANtSRRGLLLFVDEADAFLRKR 341
Cdd:cd19526   29 GILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNkyigASEQNV---RDLFSRAQ-SAKPCILFFDEFDSIAPKR 102
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
 261-338 5.13e-04

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 42.35  E-value: 5.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 261 KNKSLYR--------NILMYGPPGTGKTLFAKKLAVHSGMDY----AIMTggdvapmgreGVTAMHKLFDWANTSR---R 325
Cdd:COG2256   36 PGKPLRRaieagrlsSMILWGPPGTGKTTLARLIANATDAEFvalsAVTS----------GVKDIREVIEEARERRaygR 105

                         90       100
                 ....*....|....*....|.
gi 698409740 326 GLLLFVDE--------ADAFL 338
Cdd:COG2256  106 RTILFVDEihrfnkaqQDALL 126
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 267-414 5.91e-04

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 42.45  E-value: 5.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGD-VAPMGREGVTAMHKLFDWANTSRRGlLLFVDEADAFLRKR--AT 343
Cdd:PTZ00361 218 KGVILYGPPGTGKTLLAKAVANETSATFLRVVGSElIQKYLGDGPKLVRELFRVAEENAPS-IVFIDEIDAIGTKRydAT 296

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 698409740 344 EKISEDLRATL*FFRTG----QHSNKFMLVLASNQPEQFDWAI--NDRIDEMVNFDLPQleerERLVRMYFDRHVLK 414
Cdd:PTZ00361 297 SGGEKEIQRTMLELLNQldgfDSRGDVKVIMATNRIESLDPALirPGRIDRKIEFPNPD----EKTKRRIFEIHTSK 369
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
 268-286 6.62e-04

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 40.98  E-value: 6.62e-04
                          10
                  ....*....|....*....
gi 698409740  268 NILMYGPPGTGKTLFAKKL 286
Cdd:pfam01078  24 NLLMIGPPGSGKTMLAKRL 42
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
269-287 1.05e-03

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 41.56  E-value: 1.05e-03
                         10
                 ....*....|....*....
gi 698409740 269 ILMYGPPGTGKTLFAKKLA 287
Cdd:COG0465  178 VLLVGPPGTGKTLLAKAVA 196
Zot COG4128
Zona occludens toxin, predicted ATPase [General function prediction only];
269-433 1.71e-03

Zona occludens toxin, predicted ATPase [General function prediction only];


Pssm-ID: 443304 [Multi-domain]  Cd Length: 276  Bit Score: 40.47  E-value: 1.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 269 ILMYGPPGTGKTLFA----KKLAVHSG-------------------MDYAIMTGG---DVAPMGREGVTAMHKLFDWAnt 322
Cdd:COG4128    4 TLITGVPGSGKSYEAvwflIIPALKKGrrvitnipglkileriaehLGLAVPDTAeliNVDTDDPDGLEKMARWFHWA-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 323 sRRGLLLFVDEADAFLRKRATEKISEDLRAtl*FFRTGQHSNkFMLVLASNQPEQFDWAINDRIDEMVNF-DLPQLEERE 401
Cdd:COG4128   82 -PDGALIVIDEAQRVWPPRGKGSKPPDVVQ---AFATHRHHG-WDIVLITQNISLIHSFIRALIERHYRHrKLDGLGLRN 156

                        170       180       190
                 ....*....|....*....|....*....|..
gi 698409740 402 RLVRMYFDRHVLKPAteGKQRLKLAQFDYGKK 433
Cdd:COG4128  157 RYEWPEHDGNPGKKT--SHDKATSKRYKYPKD 186
PRK10927 PRK10927
cell division protein FtsN;
22-99 1.84e-03

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 40.43  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  22 EQLKNEQ----IRVQAEERRK--TLSEETKQHQARAQYQDKLARQRYDEQMRQQQ------LANEENLRKQEESVQKQEA 89
Cdd:PRK10927 112 EQLTPEQrqllEQMQADMRQQptQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQrlaqqsRTTEQSWQQQTRTSQAAPV 191

                         90
                 ....*....|
gi 698409740  90 MRRATVEREM 99
Cdd:PRK10927 192 QAQPRQSKPA 201
YifB COG0606
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ...
 268-286 1.93e-03

Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440371 [Multi-domain]  Cd Length: 502  Bit Score: 40.79  E-value: 1.93e-03
                         10
                 ....*....|....*....
gi 698409740 268 NILMYGPPGTGKTLFAKKL 286
Cdd:COG0606  213 NLLMIGPPGSGKTMLARRL 231
ClpX COG1219
ATP-dependent protease Clp, ATPase subunit ClpX [Posttranslational modification, protein ...
 263-287 2.03e-03

ATP-dependent protease Clp, ATPase subunit ClpX [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440832 [Multi-domain]  Cd Length: 409  Bit Score: 40.42  E-value: 2.03e-03
                         10        20
                 ....*....|....*....|....*
gi 698409740 263 KSlyrNILMYGPPGTGKTLFAKKLA 287
Cdd:COG1219  109 KS---NILLIGPTGSGKTLLAQTLA 130
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 261-338 2.12e-03

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 40.45  E-value: 2.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 261 KNKSLYR--------NILMYGPPGTGKTLFAKKLAVHSGMDY----AIMTggdvapmgreGVTAMHKLFDWANTSR---R 325
Cdd:PRK13342  23 PGKPLRRmieagrlsSMILWGPPGTGKTTLARIIAGATDAPFealsAVTS----------GVKDLREVIEEARQRRsagR 92

                         90       100
                 ....*....|....*....|.
gi 698409740 326 GLLLFVDE--------ADAFL 338
Cdd:PRK13342  93 RTILFIDEihrfnkaqQDALL 113
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 21-109 2.28e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.88  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   21 IEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQM--RQQQLANEENLRKQEESVQK----------QE 88
Cdd:pfam17380 477 LELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMeeRQKAIYEEERRREAEEERRKqqemeerrriQE 556

                          90       100
                  ....*....|....*....|...
gi 698409740   89 AMRRATVEREM--ELRHKNEMLR 109
Cdd:pfam17380 557 QMRKATEERSRleAMEREREMMR 579
clpX PRK05342
ATP-dependent Clp protease ATP-binding subunit ClpX;
263-287 2.50e-03

ATP-dependent Clp protease ATP-binding subunit ClpX;


Pssm-ID: 235422 [Multi-domain]  Cd Length: 412  Bit Score: 40.14  E-value: 2.50e-03
                         10        20
                 ....*....|....*....|....*
gi 698409740 263 KSlyrNILMYGPPGTGKTLFAKKLA 287
Cdd:PRK05342 108 KS---NILLIGPTGSGKTLLAQTLA 129
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
 267-343 3.29e-03

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 38.62  E-value: 3.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 267 RNILMYGPPGTGKTLFAKKLA-VHSGMDYAIMTGGDVAP--MGrEGVTAMHKLFDWANTSRRGL-------LLFVDEADA 336
Cdd:cd19504   36 KGILLYGPPGTGKTLMARQIGkMLNAREPKIVNGPEILNkyVG-ESEANIRKLFADAEEEQRRLgansglhIIIFDEIDA 114


                 ....*..
gi 698409740 337 FLRKRAT 343
Cdd:cd19504  115 ICKQRGS 121
PTZ00121 PTZ00121
MAEBL; Provisional
 22-148 3.33e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 3.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   22 EQLKNEQIRVQAEERRKTlSEETKQHQARAQYQDKLARQRYDEQMRQQQL--ANEENLRKQEESVQKQEAMRRATVEREM 99
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEKKA-AEALKKEAEEAKKAEELKKKEAEEKKKAEELkkAEEENKIKAEEAKKEAEEDKKKAEEAKK 1751

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 698409740  100 ELRHKNEMLRVEAEARARAKAERENAD-IIREQIRLKAAEHRQTVLESLK 148
Cdd:PTZ00121 1752 DEEEKKKIAHLKKEEEKKAEEIRKEKEaVIEEELDEEDEKRRMEVDKKIK 1801
PTZ00121 PTZ00121
MAEBL; Provisional
 12-150 3.35e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 3.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   12 AKLKEYEAaieQLKNEQIRVQAEERRKT-----LSEETKQHQARAQYQDKLARQ--RYDEQMRQQQLANEENLRKQEEsV 84
Cdd:PTZ00121 1488 AKKKAEEA---KKKADEAKKAAEAKKKAdeakkAEEAKKADEAKKAEEAKKADEakKAEEKKKADELKKAEELKKAEE-K 1563

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 698409740   85 QKQEAMRRATVEREMELRhKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTA 150
Cdd:PTZ00121 1564 KKAEEAKKAEEDKNMALR-KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA 1628
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 12-150 3.80e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.92  E-value: 3.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  12 AKLKEYEAAIEQLKNEQIRVQAEERRKTLSEetkqHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMR 91
Cdd:COG1196  260 AELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  92 RATVER-EMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTA 150
Cdd:COG1196  336 EEELEElEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 269-287 3.82e-03

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 36.81  E-value: 3.82e-03
                          10
                  ....*....|....*....
gi 698409740  269 ILMYGPPGTGKTLFAKKLA 287
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLA 19
RecA-like_ClpX cd19497
ATP-dependent Clp protease ATP-binding subunit ClpX; ClpX is a component of the ATP-dependent ...
 226-287 4.00e-03

ATP-dependent Clp protease ATP-binding subunit ClpX; ClpX is a component of the ATP-dependent protease ClpXP. In ClpXP, ClpX ATPase serves to specifically recognize, unfold, and translocate protein substrates into the chamber of ClpP protease for degradation. This RecA-like_ClpX domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410905 [Multi-domain]  Cd Length: 251  Bit Score: 39.12  E-value: 4.00e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 698409740 226 KRLTSKAQDALEGVVLSpqlearvrdiaiatrntkknKSlyrNILMYGPPGTGKTLFAKKLA 287
Cdd:cd19497   33 KRIRNNLKQKDDDVELE--------------------KS---NILLIGPTGSGKTLLAQTLA 71
ATPase pfam06745
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ...
 266-359 4.25e-03

KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.


Pssm-ID: 429095 [Multi-domain]  Cd Length: 231  Bit Score: 38.77  E-value: 4.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  266 YRNILMYGPPGTGKTLFAKKLAVHSGMDY---AIMTGGDVAPMG-REGVTAMHklFDWANTSRRGLLLFVDeADAFLRKR 341
Cdd:pfam06745  19 GRVVLITGGPGTGKTIFGLQFLYNGALKYgepGVFVTLEEPPEDlRENARSFG--WDLEKLEEEGKLAIID-ASTSGIGI 95

                          90
                  ....*....|....*...
gi 698409740  342 ATEKISEDLRATL*FFRT 359
Cdd:pfam06745  96 AEVEDRFDLEELIERLRE 113
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 12-198 4.63e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.92  E-value: 4.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  12 AKLKEYEAAIEQLKNEQIRVQAEERRK-TLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAM 90
Cdd:COG1196  351 EELEEAEAELAEAEEALLEAEAELAEAeEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  91 RRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEH------------RQTVLESLKTAGMLFGEGF 158
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALaelleelaeaaaRLLLLLEAEADYEGFLEGV 510

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 698409740 159 RAF---------------VTDWDKVTATVAGLTLLAVGVYSAKNATAVAGRYIEA 198
Cdd:COG1196  511 KAAlllaglrglagavavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
 22-106 4.64e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 39.55  E-value: 4.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   22 EQLKNEQIRVQAEERRKTLSEETKQHQ--------ARAQYQDKLARQRYDEQMRQQQLANEENLRKQEesvQKQEAMRRA 93
Cdd:pfam15709 414 LQAAQERARQQQEEFRRKLQELQRKKQqeeaeraeAEKQRQKELEMQLAEEQKRLMEMAEEERLEYQR---QKQEAEEKA 490

                          90
                  ....*....|...
gi 698409740   94 TVEREmELRHKNE 106
Cdd:pfam15709 491 RLEAE-ERRQKEE 502
McrB COG1401
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ...
 267-287 5.00e-03

5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];


Pssm-ID: 441011 [Multi-domain]  Cd Length: 477  Bit Score: 39.37  E-value: 5.00e-03
                         10        20
                 ....*....|....*....|.
gi 698409740 267 RNILMYGPPGTGKTLFAKKLA 287
Cdd:COG1401  222 KNVILAGPPGTGKTYLARRLA 242
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
 13-108 6.61e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 39.16  E-value: 6.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   13 KLKEYEAAIEQLKNEQIRVQAEER-RKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLR-----KQEESVQK 86
Cdd:pfam15709 367 QLERAEKMREELELEQQRRFEEIRlRKQRLEEERQRQEEEERKQRLQLQAAQERARQQQEEFRRKLQelqrkKQQEEAER 446

                          90       100
                  ....*....|....*....|..
gi 698409740   87 QEAMRRATVEREMELRHKNEML 108
Cdd:pfam15709 447 AEAEKQRQKELEMQLAEEQKRL 468
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 15-109 7.21e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 38.95  E-value: 7.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740   15 KEYEAAIEQLKNEQIRVQAEE------RRKTLSEETKQHQARAQYQ-------DKLA--RQRYDEQMRQQQLANEENLRK 79
Cdd:pfam17380 287 RQQQEKFEKMEQERLRQEKEEkareveRRRKLEEAEKARQAEMDRQaaiyaeqERMAmeRERELERIRQEERKRELERIR 366

                          90       100       110
                  ....*....|....*....|....*....|.
gi 698409740   80 QEESVQKQEAMRRatVER-EMELRHKNEMLR 109
Cdd:pfam17380 367 QEEIAMEISRMRE--LERlQMERQQKNERVR 395
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
 268-335 8.05e-03

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 36.89  E-value: 8.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  268 NILMYGPPGTGKTLFAKKLAV------------HSGMDYAIMTGG-DVAPMGREG-----VTAMhklfdwantsRRGLLL 329
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAalsnrpvfyvqlTRDTTEEDLFGRrNIDPGGASWvdgplVRAA----------REGEIA 70


                  ....*.
gi 698409740  330 FVDEAD 335
Cdd:pfam07728  71 VLDEIN 76
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
12-265 8.58e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.98  E-value: 8.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  12 AKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQAR-AQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQ--E 88
Cdd:COG4717  102 EELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElAELPERLEELEERLEELRELEEELEELEAELAELQEEleE 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740  89 AMRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIR-----LKAAEHRQTVLESLKTAGMLF--------- 154
Cdd:COG4717  182 LLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEeeleqLENELEAAALEERLKEARLLLliaaallal 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 698409740 155 ---GEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVRETSRITVLEALKHPIKVGKRLTSK 231
Cdd:COG4717  262 lglGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE 341

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 698409740 232 AQDALEGVV-LSPQLEARVRDIAIATRNTKKNKSL 265
Cdd:COG4717  342 LLDRIEELQeLLREAEELEEELQLEELEQEIAALL 376
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH