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Conserved domains on  [gi|672084811|ref|XP_008770714|]
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solute carrier family 12 member 4 isoform X3 [Rattus norvegicus]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
63-1080 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1323.95  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811    63 TRMEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVG 141
Cdd:TIGR00930   27 SLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVG 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   142 TAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLT 221
Cdd:TIGR00930  107 QAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLD 186
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   222 yiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYVGGIKSAFDPPVFP 301
Cdd:TIGR00930  187 -------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPAKG 258
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   302 VCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyfllnnvtEIPGIPGAAAGvlqenlwsayle 381
Cdd:TIGR00930  259 FFGLGNEIFSEN---------------------------------------------FIPGIPGPEGG------------ 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   382 kgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIVTTSLVY 461
Cdd:TIGR00930  282 ---------------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVY 328
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   462 FSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTG 520
Cdd:TIGR00930  329 LGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALASLVS 408
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   521 APRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRT 599
Cdd:TIGR00930  409 APRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRS 488
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   600 PNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGP 679
Cdd:TIGR00930  489 PGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVE 568
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   680 PHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQV 759
Cdd:TIGR00930  569 DHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAV 644
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   760 VVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNH------ 833
Cdd:TIGR00930  645 VVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqvqee 723
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   834 --------------------------------ERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDD 881
Cdd:TIGR00930  724 lendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDD 803
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   882 NSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMRLTKTERDREAqlvKDRHsalrlesly 961
Cdd:TIGR00930  804 RSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA---KDPK--------- 866
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   962 sdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfrelvhiKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGP 1041
Cdd:TIGR00930  867 ---------------MTWTKPWKITD-----------------AELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVP 914
                         1050      1060      1070
                   ....*....|....*....|....*....|....*....
gi 672084811  1042 PKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1080
Cdd:TIGR00930  915 RKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
63-1080 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1323.95  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811    63 TRMEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVG 141
Cdd:TIGR00930   27 SLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVG 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   142 TAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLT 221
Cdd:TIGR00930  107 QAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLD 186
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   222 yiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYVGGIKSAFDPPVFP 301
Cdd:TIGR00930  187 -------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPAKG 258
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   302 VCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyfllnnvtEIPGIPGAAAGvlqenlwsayle 381
Cdd:TIGR00930  259 FFGLGNEIFSEN---------------------------------------------FIPGIPGPEGG------------ 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   382 kgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIVTTSLVY 461
Cdd:TIGR00930  282 ---------------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVY 328
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   462 FSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTG 520
Cdd:TIGR00930  329 LGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALASLVS 408
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   521 APRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRT 599
Cdd:TIGR00930  409 APRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRS 488
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   600 PNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGP 679
Cdd:TIGR00930  489 PGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVE 568
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   680 PHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQV 759
Cdd:TIGR00930  569 DHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAV 644
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   760 VVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNH------ 833
Cdd:TIGR00930  645 VVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqvqee 723
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   834 --------------------------------ERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDD 881
Cdd:TIGR00930  724 lendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDD 803
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   882 NSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMRLTKTERDREAqlvKDRHsalrlesly 961
Cdd:TIGR00930  804 RSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA---KDPK--------- 866
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   962 sdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfrelvhiKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGP 1041
Cdd:TIGR00930  867 ---------------MTWTKPWKITD-----------------AELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVP 914
                         1050      1060      1070
                   ....*....|....*....|....*....|....*....
gi 672084811  1042 PKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1080
Cdd:TIGR00930  915 RKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
118-690 4.40e-50

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 184.45  E-value: 4.40e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   118 GVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVpAGGSYFMISRSLGPEFGGAVG 197
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   198 L--CFYLGTTFAAAmyiLGAIEILLTYIAPPAAIFYPSGThdmssatlnnmrvyGTIFLTFMTLVVFVGVKYVNKFASLF 275
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDIPYLWVW--------------GAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   276 LACVIISILSIYVGGIKSAFDPpvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 355
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIILLSGG---------------------------------------------------------- 164
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   356 nvteipgipGAAAGVLQENLWSAYLEKgevvekhglpstdtlglkeslslYVVADIATSFTVLVGIFFPSVTGIMAGSNR 435
Cdd:pfam00324  165 ---------NPNDGAIFRYLGDNGGKN-----------------------NFPPGFGKGFISVFVIAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   436 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVV------GTLAWPSpwVIVVGSFFS 509
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTA 290
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   510 TCGAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHGKANGEPTWALLLTALIAELGILIASLdmVAPILSMFFLMCYLFVNL 589
Cdd:pfam00324  291 ALSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGL 366
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   590 ACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR 669
Cdd:pfam00324  367 IVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVL 446
                          570       580
                   ....*....|....*....|.
gi 672084811   670 YALLRLEEGPPHTKNWRPQLL 690
Cdd:pfam00324  447 LFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
126-650 4.03e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 133.87  E-value: 4.03e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  126 NIFGVILFLRLTWMVGTAGvLQALLIVLICCCCTLLTAISMSAIATNgvVP-AGGSYFMISRSLGPEFGGAVGLCFYLGT 204
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLLSY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  205 TFAAAMYILGAIEILltyiappaAIFYPSGTHDmssatlnnmrVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISIL 284
Cdd:COG0531   102 VLAVAAVAVAFGGYL--------SSLFPAGGSV----------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  285 SIYVGGIksafdppvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdPYFLLNNVTEIPGIP 364
Cdd:COG0531   164 LFIVVGL----------------------------------------------------------FAFDPANFTPFLPAG 185
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  365 GAAAGVlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFpSVTGIMAGSNRSGDLRDAQK 444
Cdd:COG0531   186 GGLSGV--------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  445 SIPVGTILAIVTTSLVYFSSVILFGacieGVVLRDKYGDGVSRNLVVGTLAWPSP--WVIVVGSFFSTCGAGLQSLTGAP 522
Cdd:COG0531   221 NIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  523 RLLQAIAKDNIIPflRVFGH-GKANGEPTWALLLTALIAELGILI--ASLDMVAPILSMFFLMCYLFVNLACAVQtLLRT 599
Cdd:COG0531   297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-RRRR 373
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 672084811  600 PNWRPRFKYYHWALSFLGMSLCLALMFVS---SWYYALVAMVIAGMIYKYIEYQ 650
Cdd:COG0531   374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
63-1080 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1323.95  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811    63 TRMEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVG 141
Cdd:TIGR00930   27 SLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVG 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   142 TAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLT 221
Cdd:TIGR00930  107 QAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLD 186
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   222 yiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYVGGIKSAFDPPVFP 301
Cdd:TIGR00930  187 -------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPAKG 258
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   302 VCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyfllnnvtEIPGIPGAAAGvlqenlwsayle 381
Cdd:TIGR00930  259 FFGLGNEIFSEN---------------------------------------------FIPGIPGPEGG------------ 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   382 kgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIVTTSLVY 461
Cdd:TIGR00930  282 ---------------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVY 328
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   462 FSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTG 520
Cdd:TIGR00930  329 LGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALASLVS 408
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   521 APRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRT 599
Cdd:TIGR00930  409 APRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRS 488
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   600 PNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGP 679
Cdd:TIGR00930  489 PGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVE 568
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   680 PHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQV 759
Cdd:TIGR00930  569 DHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAV 644
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   760 VVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNH------ 833
Cdd:TIGR00930  645 VVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqvqee 723
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   834 --------------------------------ERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDD 881
Cdd:TIGR00930  724 lendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDD 803
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   882 NSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMRLTKTERDREAqlvKDRHsalrlesly 961
Cdd:TIGR00930  804 RSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA---KDPK--------- 866
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   962 sdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfrelvhiKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGP 1041
Cdd:TIGR00930  867 ---------------MTWTKPWKITD-----------------AELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVP 914
                         1050      1060      1070
                   ....*....|....*....|....*....|....*....
gi 672084811  1042 PKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1080
Cdd:TIGR00930  915 RKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
118-690 4.40e-50

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 184.45  E-value: 4.40e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   118 GVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVpAGGSYFMISRSLGPEFGGAVG 197
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   198 L--CFYLGTTFAAAmyiLGAIEILLTYIAPPAAIFYPSGThdmssatlnnmrvyGTIFLTFMTLVVFVGVKYVNKFASLF 275
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDIPYLWVW--------------GAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   276 LACVIISILSIYVGGIKSAFDPpvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 355
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIILLSGG---------------------------------------------------------- 164
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   356 nvteipgipGAAAGVLQENLWSAYLEKgevvekhglpstdtlglkeslslYVVADIATSFTVLVGIFFPSVTGIMAGSNR 435
Cdd:pfam00324  165 ---------NPNDGAIFRYLGDNGGKN-----------------------NFPPGFGKGFISVFVIAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   436 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVV------GTLAWPSpwVIVVGSFFS 509
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTA 290
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   510 TCGAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHGKANGEPTWALLLTALIAELGILIASLdmVAPILSMFFLMCYLFVNL 589
Cdd:pfam00324  291 ALSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGL 366
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   590 ACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR 669
Cdd:pfam00324  367 IVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVL 446
                          570       580
                   ....*....|....*....|.
gi 672084811   670 YALLRLEEGPPHTKNWRPQLL 690
Cdd:pfam00324  447 LFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
126-650 4.03e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 133.87  E-value: 4.03e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  126 NIFGVILFLRLTWMVGTAGvLQALLIVLICCCCTLLTAISMSAIATNgvVP-AGGSYFMISRSLGPEFGGAVGLCFYLGT 204
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLLSY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  205 TFAAAMYILGAIEILltyiappaAIFYPSGTHDmssatlnnmrVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISIL 284
Cdd:COG0531   102 VLAVAAVAVAFGGYL--------SSLFPAGGSV----------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  285 SIYVGGIksafdppvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdPYFLLNNVTEIPGIP 364
Cdd:COG0531   164 LFIVVGL----------------------------------------------------------FAFDPANFTPFLPAG 185
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  365 GAAAGVlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFpSVTGIMAGSNRSGDLRDAQK 444
Cdd:COG0531   186 GGLSGV--------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  445 SIPVGTILAIVTTSLVYFSSVILFGacieGVVLRDKYGDGVSRNLVVGTLAWPSP--WVIVVGSFFSTCGAGLQSLTGAP 522
Cdd:COG0531   221 NIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811  523 RLLQAIAKDNIIPflRVFGH-GKANGEPTWALLLTALIAELGILI--ASLDMVAPILSMFFLMCYLFVNLACAVQtLLRT 599
Cdd:COG0531   297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-RRRR 373
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 672084811  600 PNWRPRFKYYHWALSFLGMSLCLALMFVS---SWYYALVAMVIAGMIYKYIEYQ 650
Cdd:COG0531   374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
704-1080 5.42e-24

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 106.16  E-value: 5.42e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   704 PRLLTFASQLKAGKGLTIVGSVIQGSFleSYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRH 783
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGRL--SQKLRSELQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKP 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   784 NSVVLGWPYGWRQSE----------------------------------------------------------------- 798
Cdd:pfam03522   80 NILLMGYKSDWRTCDkeeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   799 DPRAWKTFIDTVRCTTAAHLALLV--------------------PKNIAFYPSNHERYLE-----------GHIDVWWIV 847
Cdd:pfam03522  160 NSKQDDDKSKLSKKDSNLSLSPDKstknpsgkdssksdklkkksPSIILRTASNEKEILNnitqfqkkqkkGTIDVWWLY 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   848 HDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLE-AEVEVVemhnSDISAYTYERTLMMEQ 926
Cdd:pfam03522  240 DDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDELEEEQRNMASLLSKFRIDySDLTVI----PDITKKPKKETKKFFD 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   927 rsQMLRQMRLTKTErdreaqlvKDRHSALRLeslySDEEDESVtgadkiqmtwtRDKymaepwdpshapdNFRELvhikp 1006
Cdd:pfam03522  316 --ELIEPFRLHEDD--------KEEESAEKI----TDSELEAL-----------KEK-------------TNRQL----- 352
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672084811  1007 dqsnvrrmhtavKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1080
Cdd:pfam03522  353 ------------RLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease_2 pfam13520
Amino acid permease;
406-647 2.55e-13

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 73.50  E-value: 2.55e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   406 YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRdaQKSIPVGTILAIVTTSLVYFSSVILFGACI--EGVVLRDKYGD 483
Cdd:pfam13520  181 TFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYILVNIAFFGVVpdDEIALSSGLGQ 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   484 GVS---RNLVVGTLAWpspwVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTALIA 560
Cdd:pfam13520  259 VAAllfQAVGGKWGAI----IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILS 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672084811   561 ELGILIASLDMVAPI----LSMFFLMCYLFVNLACAVqtLLRTPNWRPRFKYYHWALSFLGMsLCLALMFVSSWYYALVA 636
Cdd:pfam13520  335 LILLLLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGI-LFSLFLIVALFFPPVGP 411
                          250
                   ....*....|.
gi 672084811   637 MVIAGMIYKYI 647
Cdd:pfam13520  412 ATGSSLNYAII 422
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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