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Conserved domains on  [gi|1938857078|ref|XP_008007824|]
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GPI mannosyltransferase 4 isoform X2 [Chlorocebus sabaeus]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 44-434 1.20e-30

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member pfam03901:

Pssm-ID: 473917  Cd Length: 414  Bit Score: 124.01  E-value: 1.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078  44 LRVLWCLLPQTGyvHPDEFFQSPEVmAEDILGVQATRPWEFYPSSPCRTVVFPLLTSGSTFWLLRLWGElgpwpglvSSY 123
Cdd:pfam03901   9 LRLLLALLVQTS--DPDEHFQSWEP-LHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGD--------SKY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 124 ALLVGPRLLLAALSFALDGVVYHLAPLL--GADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFAWLLVLVSPHVMwgpt 201
Cdd:pfam03901  78 LVFYAPRLLLGLFSALCDYYLYRAVCRKygLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGN---- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 202 crePVPGPWWHSWLLGGIVTAGFFNRPTFLAFaVVPLYLWGTRGATNPGLKSLTREALVLLPGAA-LTAVVFVAMDSWYF 280
Cdd:pfam03901 154 ---TSVSNYKYLKAVLLIAALAILGRPTSALL-WLPLVLYLLLRLRGKRLKLFLFLAISLGLLVAlLVLGAVILIDSYFY 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 281 SSpatsrtLVLTPVNFLHYNLNPQNLARHGTHVRLTHLAVNGFLLFGVLhaqalqaawqqlqagLQASLQMGLLRALGAR 360
Cdd:pfam03901 230 GR------FVFTPLNFLKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPF---------------LLAFILGPLVLLLRKV 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 361 SLLSSprsyLLLLYFMPLALLSAFSHQEARFLIPLLvPVVLLCSPQT------------QPVPWKGTVVLFNALGAFFFG 428
Cdd:pfam03901 289 SRLSQ----LLAPILIWLFIYSLQPHKEERFLYPVY-PLILLSAAIAltrlsrrswkvrKKLSLLFLLLFFNVSLARLFG 363


                  ....*.
gi 1938857078 429 CLHQGG 434
Cdd:pfam03901 364 LVHQYG 369
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 44-434 1.20e-30

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 124.01  E-value: 1.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078  44 LRVLWCLLPQTGyvHPDEFFQSPEVmAEDILGVQATRPWEFYPSSPCRTVVFPLLTSGSTFWLLRLWGElgpwpglvSSY 123
Cdd:pfam03901   9 LRLLLALLVQTS--DPDEHFQSWEP-LHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGD--------SKY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 124 ALLVGPRLLLAALSFALDGVVYHLAPLL--GADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFAWLLVLVSPHVMwgpt 201
Cdd:pfam03901  78 LVFYAPRLLLGLFSALCDYYLYRAVCRKygLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGN---- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 202 crePVPGPWWHSWLLGGIVTAGFFNRPTFLAFaVVPLYLWGTRGATNPGLKSLTREALVLLPGAA-LTAVVFVAMDSWYF 280
Cdd:pfam03901 154 ---TSVSNYKYLKAVLLIAALAILGRPTSALL-WLPLVLYLLLRLRGKRLKLFLFLAISLGLLVAlLVLGAVILIDSYFY 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 281 SSpatsrtLVLTPVNFLHYNLNPQNLARHGTHVRLTHLAVNGFLLFGVLhaqalqaawqqlqagLQASLQMGLLRALGAR 360
Cdd:pfam03901 230 GR------FVFTPLNFLKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPF---------------LLAFILGPLVLLLRKV 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 361 SLLSSprsyLLLLYFMPLALLSAFSHQEARFLIPLLvPVVLLCSPQT------------QPVPWKGTVVLFNALGAFFFG 428
Cdd:pfam03901 289 SRLSQ----LLAPILIWLFIYSLQPHKEERFLYPVY-PLILLSAAIAltrlsrrswkvrKKLSLLFLLLFFNVSLARLFG 363


                  ....*.
gi 1938857078 429 CLHQGG 434
Cdd:pfam03901 364 LVHQYG 369
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 44-434 1.20e-30

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 124.01  E-value: 1.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078  44 LRVLWCLLPQTGyvHPDEFFQSPEVmAEDILGVQATRPWEFYPSSPCRTVVFPLLTSGSTFWLLRLWGElgpwpglvSSY 123
Cdd:pfam03901   9 LRLLLALLVQTS--DPDEHFQSWEP-LHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGD--------SKY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 124 ALLVGPRLLLAALSFALDGVVYHLAPLL--GADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFAWLLVLVSPHVMwgpt 201
Cdd:pfam03901  78 LVFYAPRLLLGLFSALCDYYLYRAVCRKygLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGN---- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 202 crePVPGPWWHSWLLGGIVTAGFFNRPTFLAFaVVPLYLWGTRGATNPGLKSLTREALVLLPGAA-LTAVVFVAMDSWYF 280
Cdd:pfam03901 154 ---TSVSNYKYLKAVLLIAALAILGRPTSALL-WLPLVLYLLLRLRGKRLKLFLFLAISLGLLVAlLVLGAVILIDSYFY 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 281 SSpatsrtLVLTPVNFLHYNLNPQNLARHGTHVRLTHLAVNGFLLFGVLhaqalqaawqqlqagLQASLQMGLLRALGAR 360
Cdd:pfam03901 230 GR------FVFTPLNFLKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPF---------------LLAFILGPLVLLLRKV 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938857078 361 SLLSSprsyLLLLYFMPLALLSAFSHQEARFLIPLLvPVVLLCSPQT------------QPVPWKGTVVLFNALGAFFFG 428
Cdd:pfam03901 289 SRLSQ----LLAPILIWLFIYSLQPHKEERFLYPVY-PLILLSAAIAltrlsrrswkvrKKLSLLFLLLFFNVSLARLFG 363


                  ....*.
gi 1938857078 429 CLHQGG 434
Cdd:pfam03901 364 LVHQYG 369
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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