|
Name |
Accession |
Description |
Interval |
E-value |
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
118-331 |
1.10e-102 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 300.30 E-value: 1.10e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 118 MKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFmvdrvvdlataciqhlqliaekhkgeehrkale 197
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF--------------------------------- 47
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 198 dftldnilsHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHR 277
Cdd:cd19492 48 ---------NIHYFRVHDYVELLALINSLPKFLEDHPKVKLIVVDSIAFPFRHDFDDLAQRTRLLNGLAQLLHSLARQHN 118
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 578831207 278 LAVILTNQMTTKIDRN-QALLVPALGESWGHAATIRLIFHWDRKQsRLATLYKSP 331
Cdd:cd19492 119 LAVVLTNQVTTKISEDgQSQLVPALGESWSHACTTRLFLTWDEKQ-RFAHLYKSP 172
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
21-349 |
8.35e-50 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 169.54 E-value: 8.35e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 21 PAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECltnkpryagtsESHKKCTALELLEQEHTQGFI 100
Cdd:TIGR02236 9 PATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAA-----------DLGGFETADDVLERRKTIGKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 101 ITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLAtaciqhl 180
Cdd:TIGR02236 78 TTGSKELDELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMA------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 181 qliaekhkgeEHRKALEDFTLDNilshIYYFRCRDYTELLAQVYLLPDFLSEHSK-VRLVIVDGIAFPFRHDL---DDLS 256
Cdd:TIGR02236 151 ----------EARGLDPDEVLKN----IYVARAYNSNHQMLLVEKAEDLIKELNNpVKLLIVDSLTSHFRAEYvgrGALA 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 257 LRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDrnqAL----LVPALGESWGHAATIRLIFHWDRKQSRLATLYKSPS 332
Cdd:TIGR02236 217 ERQQKLNKHLHDLLRLADLYNAAVVVTNQVMARPD---AFfgdpTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPH 293
|
330
....*....|....*..
gi 578831207 333 QKECTVLFQIKPQGFRD 349
Cdd:TIGR02236 294 LPEGEAVFRITEKGIED 310
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
119-317 |
4.83e-49 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 163.68 E-value: 4.83e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 119 KTTEICGAPGVGKTQLCMQLAVDVQIPEcfggvaGEAVFIDTEGSFMVDRVVDLATACIQhlqliaekhkgeehrkalED 198
Cdd:cd01393 2 KITEIYGPPGSGKTQLALQLAANALLLG------GGVVWIDTEGAFPPSRLVQILEASPS------------------SE 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 199 FTLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDLDD-------LSLRTRLLNGLAQQMIS 271
Cdd:cd01393 58 LELAEALSRLLYFRPPDTLAHLLALDSLPESLFPPPNTSLVVVDSVSALFRKAFPRggdgdssSSLRARLLSQLARALQK 137
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 578831207 272 LANNHRLAVILTNQMTTKID--RNQALLVPALGESWGHAATIRLIFHW 317
Cdd:cd01393 138 LAAQFNLAVVVTNQVTTKIRggSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
10-349 |
2.58e-48 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 165.82 E-value: 2.58e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 10 MQRDLVSFP-LSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALetlQIIR--RECLTnkpryAGTSEshkkcT 86
Cdd:PRK04301 4 KEKDLEDLPgVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAA---KIIEaaREAAD-----IGGFE-----T 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 87 ALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMV 166
Cdd:PRK04301 71 ALEVLERRKNVGKITTGSKELDELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRP 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 167 DRVVDLAtaciqhlqliaekhkgeEHRKALEDFTLDNilshIYYFRCR--DYTELLAQVylLPDFLSEHSKVRLVIVDGI 244
Cdd:PRK04301 151 ERIEQMA-----------------EALGLDPDEVLDN----IHVARAYnsDHQMLLAEK--AEELIKEGENIKLVIVDSL 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 245 AFPFRHD---LDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDrnqAL----LVPALGESWGHAATIRLIFHW 317
Cdd:PRK04301 208 TAHFRAEyvgRGNLAERQQKLNKHLHDLLRLADLYNAAVVVTNQVMARPD---AFfgdpTQPIGGHILGHTATFRIYLRK 284
|
330 340 350
....*....|....*....|....*....|..
gi 578831207 318 DRKQSRLATLYKSPSQKECTVLFQIKPQGFRD 349
Cdd:PRK04301 285 SKGNKRIARLVDSPHLPEGEAVFRITEEGIRD 316
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
107-338 |
3.74e-45 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 155.53 E-value: 3.74e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLatACIQHLQLIAEK 186
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQL--ASSLPKRYHLEK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 187 HKgeehrkaledftldNILSHIYYFRCRDYTELLAQV-YLLPDFLsEHSKVRLVIVDGIAFPFRHDLD----DLSLRTRL 261
Cdd:cd19491 79 AK--------------NFLDNIFVEHVADLETLEHCLnYQLPALL-ERGPIRLVVIDSIAALFRSEFDtsrsDLVERAKY 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 262 LNGLAQQMISLANNHRLAVILTNQMTTKIDRN-----------------------QALLVPALGESWGHAATIRLIFhwd 318
Cdd:cd19491 144 LRRLADHLKRLADKYNLAVVVVNQVTDRFDSSsdasglgvldylsqfssfsggvsGNRKVPALGLTWANLVNTRLML--- 220
|
250 260
....*....|....*....|
gi 578831207 319 rkqSRLATLYKSPSQKECTV 338
Cdd:cd19491 221 ---SRTPKRITDSSAASISV 237
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
86-349 |
1.11e-44 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 154.77 E-value: 1.11e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 86 TALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFM 165
Cdd:pfam08423 5 TATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTEGTFR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 166 VDRVVDlataciqhlqlIAEKHK--GEEhrkaledfTLDNILShiyyfrCRDYT-----ELLAQvylLPDFLSEhSKVRL 238
Cdd:pfam08423 85 PERLVA-----------IAERYGldPED--------VLDNVAY------ARAYNsehqmQLLQQ---AAAMMSE-SRFAL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 239 VIVDGIAFPFRHD---LDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLV-----PALGESWGHAAT 310
Cdd:pfam08423 136 LIVDSATALYRTDfsgRGELAERQQHLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAGMFSgdpkkPIGGHIMAHAST 215
|
250 260 270
....*....|....*....|....*....|....*....
gi 578831207 311 IRLIFHWDRKQSRLATLYKSPSQKECTVLFQIKPQGFRD 349
Cdd:pfam08423 216 TRLSLRKGRGEQRICKIYDSPCLPESEAVFAIGSGGIID 254
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
100-349 |
3.90e-40 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 142.11 E-value: 3.90e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 100 IITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDlataciqh 179
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRP-------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 180 lqlIAEKHkGEEHRKAledftLDNILshiyYFRCrdYT-----ELLAQVyllPDFLSEHSKVRLVIVDGIAFPFRHDLD- 253
Cdd:cd19514 73 ---IAERF-GVDHDAV-----LDNIL----YARA--YTsehqmELLDYV---AAKFHEEAVFRLLIIDSIMALFRVDFSg 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 254 --DLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTkiDRNQALLV------PALGESWGHAATIRLIFHWDRKQSRLA 325
Cdd:cd19514 135 rgELAERQQKLAQMLSRLQKISEEYNVAVFITNQVTA--DPGAAMTFqadpkkPIGGHILAHASTTRISLRKGRGEERIA 212
|
250 260
....*....|....*....|....
gi 578831207 326 TLYKSPSQKECTVLFQIKPQGFRD 349
Cdd:cd19514 213 KIYDSPDLPENEATFAITAGGIAD 236
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
100-349 |
4.83e-39 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 139.04 E-value: 4.83e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 100 IITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLAtaciqh 179
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMA------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 180 lqliaeKHKGEEhrkaledftLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDL---DDLS 256
Cdd:cd19515 75 ------KALGLD---------PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNNIKLLIVDSLTSHFRAEYvgrGTLA 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 257 LRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQAL-LVPALGESWGHAATIRLIFHWDRKQSRLATLYKSPSQKE 335
Cdd:cd19515 140 ERQQKLNKHLHDLHRLADLYNIAVLVTNQVMAKPDAFFGDpTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPE 219
|
250
....*....|....
gi 578831207 336 CTVLFQIKPQGFRD 349
Cdd:cd19515 220 GEAVFRITEKGIED 233
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
108-332 |
9.43e-39 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 137.84 E-value: 9.43e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 108 DDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLAtaciqhlqliAEKH 187
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIA----------EARF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 188 KGEEHRKALEDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHsKVRLVIVDGIAFPFRHD----LDDLSLRTRLLN 263
Cdd:cd19493 71 PEAFSGFMEENERAEEMLKRVAVVRVTTLAQLLERLPNLEEHILSS-GVRLVVIDSIAALVRREfggsDGEVTERHNALA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578831207 264 GLAQQMISLANNHRLAVILTNQMTTKIDRNQ---ALLVPALGESWGHAATIRLIFHWDRKQS-RLATLYKSPS 332
Cdd:cd19493 150 REASSLKRLAEEFRIAVLVTNQATTHFGDAGdgsSGVTAALGDAWAHAVNTRLRLERCLLQLrRVLEIVKSPL 222
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
26-349 |
3.39e-37 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 137.05 E-value: 3.39e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 26 KLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKpryagtseshkkCTALELLEQEHTQGFIITFCS 105
Cdd:PTZ00035 38 KLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVPMGF------------ISATEYLEARKNIIRITTGST 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 106 ALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDlataciqhlqlIAE 185
Cdd:PTZ00035 106 QLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFRPERIVQ-----------IAE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 186 KHK--GEEhrkaledfTLDNILshiyYFRCrdYT-----ELLAQVyllPDFLSEhSKVRLVIVDGIAFPFRHDLD---DL 255
Cdd:PTZ00035 175 RFGldPED--------VLDNIA----YARA--YNhehqmQLLSQA---AAKMAE-ERFALLIVDSATALFRVDYSgrgEL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 256 SLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALL----VPALGESWGHAATIRLIFHWDRKQSRLATLYKSP 331
Cdd:PTZ00035 237 AERQQHLGKFLRALQKLADEFNVAVVITNQVMADVDGASMFVadpkKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSP 316
|
330
....*....|....*...
gi 578831207 332 SQKECTVLFQIKPQGFRD 349
Cdd:PTZ00035 317 NLPESEAVFAISEGGIID 334
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
26-349 |
9.34e-36 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 132.59 E-value: 9.34e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 26 KLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECltnKPRYAgtseshkkcTALELLEQEHTQGFIITFCS 105
Cdd:TIGR02238 16 KLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKII---NPGFI---------TAFEISQKRKKVLKITTGSQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 106 ALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDlataciqhlqlIAE 185
Cdd:TIGR02238 84 ALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRA-----------IAE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 186 KHkGEEHrkaleDFTLDNILshiyYFRCRDYTELLAQVYLLPDFLSEhSKVRLVIVDGIAFPFRHDLD---DLSLRTRLL 262
Cdd:TIGR02238 153 RF-GVDP-----DAVLDNIL----YARAYTSEHQMELLDYLAAKFSE-EPFRLLIVDSIMALFRVDFSgrgELSERQQKL 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 263 NGLAQQMISLANNHRLAVILTNQMTTkiDRNQALLV------PALGESWGHAATIRLIFHWDRKQSRLATLYKSPSQKEC 336
Cdd:TIGR02238 222 AQMLSRLNKISEEFNVAVFVTNQVQA--DPGATMTFiadpkkPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEA 299
|
330
....*....|...
gi 578831207 337 TVLFQIKPQGFRD 349
Cdd:TIGR02238 300 EASFQITEGGIAD 312
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
100-346 |
2.03e-34 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 126.88 E-value: 2.03e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 100 IITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLAtaciqh 179
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIA------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 180 lqliaeKHKGEEHrkaledftlDNILSHIYYFRCRDYTELLAQVYLLPDFLSEhSKVRLVIVDGIAFPFRHDLD---DLS 256
Cdd:cd01123 75 ------QRFGLDP---------DDVLDNVAYARAFNSDHQTQLLDQAAAMMVE-SRFKLLIVDSATALYRTDYSgrgELS 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 257 LRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLV----PALGESWGHAATIRLIFHWDRKQSRLATLYKSPS 332
Cdd:cd01123 139 ARQMHLAKFLRMLQRLADEFGVAVVVTNQVVAQVDGAMMFAAdpkkPIGGNILAHASTTRLYLRKGRGETRICKIYDSPC 218
|
250
....*....|....
gi 578831207 333 QKECTVLFQIKPQG 346
Cdd:cd01123 219 LPEAEAVFAITADG 232
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
8-349 |
7.74e-34 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 128.36 E-value: 7.74e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 8 FEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRecLTNKpryagtseshKKCTA 87
Cdd:PLN03187 28 FESIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEK--LLNQ----------GFITG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 88 LELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVD 167
Cdd:PLN03187 96 SDALLKRKSVVRITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 168 RVVDLAtaciqhlqliaekhkgeehrkalEDFTLDN--ILSHIYYFRCRDYTELLAQVYLLPDFLSEHSkVRLVIVDGIA 245
Cdd:PLN03187 176 RIVPIA-----------------------ERFGMDAdaVLDNIIYARAYTYEHQYNLLLGLAAKMAEEP-FRLLIVDSVI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 246 FPFRHDL---DDLSLRTRLLNGLAQQMISLANNHRLAVILTNQ-------MTTKIDRNQallvPALGESWGHAATIRLIF 315
Cdd:PLN03187 232 ALFRVDFtgrGELAERQQKLAQMLSRLTKIAEEFNVAVYMTNQviadpggGMFISDPKK----PAGGHVLAHAATIRLML 307
|
330 340 350
....*....|....*....|....*....|....
gi 578831207 316 HWDRKQSRLATLYKSPSQKECTVLFQIKPQGFRD 349
Cdd:PLN03187 308 RKGKGEQRVCKVFDAPNLPEAEAEFQITSGGIMD 341
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
26-350 |
3.23e-33 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 126.39 E-value: 3.23e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 26 KLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQiirrecLTNKPRYAGTseshkkCTALELLEQEHTQGFIITFCS 105
Cdd:PLN03186 43 KLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILE------AASKLVPLGF------TTASQLHAQRQEIIQITTGSR 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 106 ALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDlataciqhlqlIAE 185
Cdd:PLN03186 111 ELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDTEGTFRPQRLIQ-----------IAE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 186 KhkgeehrkaledFTLD--NILSHIYYFRCRDyTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDLD---DLSLRTR 260
Cdd:PLN03186 180 R------------FGLNgaDVLENVAYARAYN-TDHQSELLLEAASMMAETRFALMIVDSATALYRTEFSgrgELSARQM 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 261 LLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQ----ALLVPALGESWGHAATIRLIFHWDRKQSRLATLYKSPSQKEC 336
Cdd:PLN03186 247 HLGKFLRSLQRLADEFGVAVVITNQVVAQVDGSAffagPQLKPIGGNIMAHASTTRLALRKGRGENRICKVISSPCLPEA 326
|
330
....*....|....
gi 578831207 337 TVLFQIKPQGFRDT 350
Cdd:PLN03186 327 EARFSISSEGVTDV 340
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
100-349 |
3.90e-30 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 115.49 E-value: 3.90e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 100 IITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRvvdlataciqh 179
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPER----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 180 LQLIAEKHK--GEEhrkaledfTLDNIlSHIYYFRCRDYTELLAQVYLLpdfLSEhSKVRLVIVDGIAFPFRHDLD---D 254
Cdd:cd19513 70 LLAIAERYGlnGED--------VLDNV-AYARAYNTDHQMQLLIQASAM---MAE-SRYALLIVDSATALYRTDYSgrgE 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 255 LSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPAL----GESWGHAATIRLIFHWDRKQSRLATLYKS 330
Cdd:cd19513 137 LSARQMHLAKFLRMLQRLADEFGVAVVITNQVVAQVDGAAMFAGDPKkpigGNIMAHASTTRLYLRKGRGETRICKIYDS 216
|
250
....*....|....*....
gi 578831207 331 PSQKECTVLFQIKPQGFRD 349
Cdd:cd19513 217 PCLPEAEAVFAITEDGIGD 235
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
26-349 |
6.98e-30 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 116.75 E-value: 6.98e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 26 KLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLqiirrecltnkpryagtSESHKK-----CTALELLEQEHTQGFI 100
Cdd:TIGR02239 16 KLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKIL-----------------AEAAKLvpmgfTTATEFHQRRQEVIQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 101 ITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDlataciqhl 180
Cdd:TIGR02239 79 TTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLA--------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 181 qlIAEKHK--GEEhrkaledfTLDNIlSHIYYFRCRDYTELLAQVYLLpdfLSEhSKVRLVIVDGIAFPFRHDLD---DL 255
Cdd:TIGR02239 150 --IAERYGlnPED--------VLDNV-AYARAYNTDHQLQLLQQAAAM---MSE-SRFALLIVDSATALYRTDFSgrgEL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 256 SLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLV-----PALGESWGHAATIRLIFHWDRKQSRLATLYKS 330
Cdd:TIGR02239 215 SARQMHLARFLRSLQRLADEFGVAVVITNQVVAQVDGAGSMFAgdpkkPIGGNIMAHASTTRLSLRKGRGEQRICKIYDS 294
|
330
....*....|....*....
gi 578831207 331 PSQKECTVLFQIKPQGFRD 349
Cdd:TIGR02239 295 PCLPESEAMFAIYEDGIGD 313
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
100-349 |
1.73e-29 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 113.42 E-value: 1.73e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 100 IITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPEcfggvaGEAVFIDTEGsFMVDRVVDLATaciqh 179
Cdd:PRK09361 5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQLAVEAAKNG------KKVIYIDTEG-LSPERFKQIAG----- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 180 lqliaekhkgeehrkalEDFtlDNILSHIYYFRCRDYTELLAQVYLLPDFLSEhsKVRLVIVDGIAFPFRHDLDDLSLRT 259
Cdd:PRK09361 73 -----------------EDF--EELLSNIIIFEPSSFEEQSEAIRKAEKLAKE--NVGLIVLDSATSLYRLELEDEEDNS 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 260 RLLNGLAQQM---ISLANNHRLAVILTNQMTTKIDRNQallVPALGEswghaatiRLIFHW---------DRKQSRLATL 327
Cdd:PRK09361 132 KLNRELGRQLthlLKLARKHDLAVVITNQVYSDIDSDG---LRPLGG--------HTLEHWsktilrlekFRNGKRRATL 200
|
250 260
....*....|....*....|...
gi 578831207 328 YKSPSQKEC-TVLFQIKPQGFRD 349
Cdd:PRK09361 201 EKHRSRPEGeSAEFRITDRGIEI 223
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
100-348 |
1.58e-26 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 105.09 E-value: 1.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 100 IITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVqipecfGGVAGEAVFIDTEGsFMVDRVVDLAtaciqh 179
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEA------AKQGKKVVYIDTEG-LSPERFQQIA------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 180 lqliaekhkGEEHRKaledftldnILSHIYYFRCRDYTELLAQVYLLPDFLSEHsKVRLVIVDGIAFPFRHDLDDLSlrt 259
Cdd:cd01394 68 ---------GERFES---------IASNIIVFEPYSFDEQGVAIQEAEKLLKSD-KVDLVVVDSATALYRLELGDDS--- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 260 RLLNGLAQQMI---SLANNHRLAVILTNQMTTKIDRNQALLVPalGESWGHA--ATIRLifhwDRKQ--SRLATLYKSPS 332
Cdd:cd01394 126 EANRELSRQMSkllSIARKYDIPVVITNQVYSDIDDDRLKPVG--GTLLEHWskAIIRL----EKSPpgLRRATLEKHRS 199
|
250
....*....|....*..
gi 578831207 333 QKE-CTVLFQIKPQGFR 348
Cdd:cd01394 200 RPEgQSAGFRITDRGIR 216
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
112-330 |
1.37e-25 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 102.33 E-value: 1.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 112 GGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQipeCFGGVAgeAVFIDTEGSFMVDRVVDLATACIQHLQLIAEkhkgee 191
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAANVA---SRSGQN--VLYIDTKSSFSARRLAQILKSRAQDAEEIDK------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 192 hrkaledftldnILSHIYYFRCRDYTELLAQVYLLPDFLS-----EHSKVRLVIVDGIAFPFRHDLDDLSLR--TRLLNG 264
Cdd:cd19489 70 ------------ALQRIRVVRVFDPYELLDLLEELRNTLSqqqenLYSRLKLVIIDSLSALISPLLGGSKHSegHALLAS 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578831207 265 LAQQMISLANNHRLAVILTNQMTTKID-RNQALLVPALGESWGHAATIRLIF-----HWDRKQSRLATLYKS 330
Cdd:cd19489 138 LARLLKKLAAEYQIAVLVTNLTVRGGDgGQQGSTKPALGEYWESVPSTRLLLsrdenDPEESGVCTATLLKS 209
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
122-316 |
8.17e-25 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 100.89 E-value: 8.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 122 EICGAPGVGKTQLCMQLAVDVQIPECFGGVA-----GEAVFIDTEGSFMVDRVVDLATACIQHLQLIAEKHKGEEHRkal 196
Cdd:cd19490 5 EITGPSGSGKTELLYHLAARCILPSSWGGVPlggleAAVVFIDTDGRFDILRLRSILEARIRAAIQAANSSDDEEDV--- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 197 eDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFL---SEHSKVRLVIVDGIAFPFRHD-------LDDLSLRTRLLNGLA 266
Cdd:cd19490 82 -EEIARECLQRLHIFRCHSSLQLLATLLSLENYLlslSANPELGLLLIDSISAFYWQDrfsaelaRAAPLLQEAALRAIL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578831207 267 QQMISLANNHRLAVILTNQM--------TTKIDRNQALLVP-------ALGESWGHAATIRLIFH 316
Cdd:cd19490 161 RELRRLRRRFQLVVIATKQAlfpgksasTDNPAANNAVSKAsapshreYLPRPWQRLVTHRLVLS 225
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
107-346 |
8.46e-18 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 80.92 E-value: 8.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQipecfgGVAGEAVFIDTEGsFMVDRVVDLATAciqhlqliaek 186
Cdd:TIGR02237 1 IDELLGGGVERGTITQIYGPPGSGKTNICMILAVNAA------RQGKKVVYIDTEG-LSPERFKQIAED----------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 187 hkgeehrkaledfTLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHsKVRLVIVDGIAFPFRHDL-DDLSLRTRLLNGL 265
Cdd:TIGR02237 63 -------------RPERALSNFIVFEVFDFDEQGVAIQKTSKFIDRD-SASLVVVDSFTALYRLELsDDRISRNRELARQ 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 266 AQQMISLANNHRLAVILTNQMTTKIDRNQALlvPALGESWGHAAtiRLIFHWDR-KQSRLATLYKSPSQKEC-TVLFQIK 343
Cdd:TIGR02237 129 LTLLLSLARKKNLAVVITNQVYTDVNNGTLR--PLGGHLLEHWS--KVILRLEKfRGRRLATLEKHRSRPEGeSVYFRIT 204
|
...
gi 578831207 344 PQG 346
Cdd:TIGR02237 205 DDG 207
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
107-288 |
7.69e-08 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 52.61 E-value: 7.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDvqipecfGGVAGE-AVFIDTEGSfmVDRVVDLAtaciqhlqliae 185
Cdd:COG0467 9 LDELLGGGLPRGSSTLLSGPPGTGKTTLALQFLAE-------GLRRGEkGLYVSFEES--PEQLLRRA------------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 186 KHKGEEHRKALEDFTLdNILSHIYYFRCRDYTELLAQvylLPDFLSEHsKVRLVIVDGIAfPFRHDLDDLSLRTRLLNGL 265
Cdd:COG0467 68 ESLGLDLEEYIESGLL-RIIDLSPEELGLDLEELLAR---LREAVEEF-GAKRVVIDSLS-GLLLALPDPERLREFLHRL 141
|
170 180
....*....|....*....|...
gi 578831207 266 aqqmISLANNHRLAVILTNQMTT 288
Cdd:COG0467 142 ----LRYLKKRGVTTLLTSETGG 160
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
100-164 |
1.87e-07 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 52.48 E-value: 1.87e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578831207 100 IITFCSALDDILG-GGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPecfGGVageAVFIDTEGSF 164
Cdd:COG0468 44 ISTGSLALDIALGvGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKA---GGI---AAFIDAEHAL 103
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
98-283 |
1.06e-06 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 48.53 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 98 GFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDV--QIPECFGGVAGEA---VFIDTEGSF--MVDRVv 170
Cdd:pfam13481 13 DGLAAPPPPRRWLIKGLLPAGGLGLLAGAPGTGKTTLALDLAAAVatGKPWLGGPRVPEQgkvLYVSAEGPAdeLRRRL- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 171 dlataciqhlqliaekhkgeehRKALEDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFLS-------EHSKVRLVIVDG 243
Cdd:pfam13481 92 ----------------------RAAGADLDLPARLLFLSLVESLPLFFLDRGGPLLDADVDaleaaleEVEDPDLVVIDP 149
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 578831207 244 IAFPFRHDLDDLSLRTRLLNGLAQqmisLANNHRLAVILT 283
Cdd:pfam13481 150 LARALGGDENSNSDVGRLVKALDR----LARRTGATVLLV 185
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
107-140 |
6.97e-05 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 43.77 E-value: 6.97e-05
10 20 30
....*....|....*....|....*....|....
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAV 140
Cdd:pfam06745 8 LDEILKGGFPEGRVVLITGGPGTGKTIFGLQFLY 41
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
107-137 |
7.87e-05 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 44.49 E-value: 7.87e-05
10 20 30
....*....|....*....|....*....|.
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQ 137
Cdd:PRK09302 20 FDDITHGGLPKGRPTLVSGTAGTGKTLFALQ 50
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
107-140 |
3.21e-04 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 41.48 E-value: 3.21e-04
10 20 30
....*....|....*....|....*....|....
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAV 140
Cdd:cd01124 8 LDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFLY 41
|
|
| KaiC-N |
cd19485 |
N-terminal domain of Circadian Clock Protein Kaic; KaiC is a circadian clock protein, most ... |
107-137 |
4.27e-04 |
|
N-terminal domain of Circadian Clock Protein Kaic; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410893 [Multi-domain] Cd Length: 226 Bit Score: 41.20 E-value: 4.27e-04
10 20 30
....*....|....*....|....*....|.
gi 578831207 107 LDDILGGGVPLMKTTEICGAPGVGKTQLCMQ 137
Cdd:cd19485 8 FDDITHGGLPKGRPTLICGTAGTGKTLFAAQ 38
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
99-164 |
6.28e-04 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 41.00 E-value: 6.28e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578831207 99 FIITFCSALDDILG-GGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIpecFGGVageAVFIDTEGSF 164
Cdd:cd00983 4 VIPTGSLSLDIALGiGGLPRGRIIEIYGPESSGKTTLALHAIAEAQK---LGGT---AAFIDAEHAL 64
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
110-282 |
2.20e-03 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 39.50 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 110 ILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGV---AGEAVFIDTEGSF--MVDRVVDLATACiqhlqlia 184
Cdd:COG3598 5 LVPGLLPEGGVTLLAGPPGTGKSFLALQLAAAVAAGGPWLGRrvpPGKVLYLAAEDDRgeLRRRLKALGADL-------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578831207 185 ekhkgeehrkaleDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFLsEHSKVRLVIVDGIAFPFRHDLDDLSLRTRLLNG 264
Cdd:COG3598 77 -------------GLPFADLDGRLRLLSLAGDLDDTDDLEALERAI-EEEGPDLVVIDPLARVFGGDENDAEEMRAFLNP 142
|
170
....*....|....*...
gi 578831207 265 LAQqmisLANNHRLAVIL 282
Cdd:COG3598 143 LDR----LAERTGAAVLL 156
|
|
| |
