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Conserved domains on  [gi|578811965|ref|XP_006715272|]
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leukocyte-specific transcript 1 protein isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LST1 super family cl04927
LST-1 protein; B144/LST1 is a gene encoded in the human major histocompatibility complex that ...
 7-72 8.57e-27

LST-1 protein; B144/LST1 is a gene encoded in the human major histocompatibility complex that produces multiple forms of alternatively spliced mRNA and encodes peptides fewer than 100 amino acids in length. B144/LST1 is strongly expressed in dendritic cells. Transfection of B144/LST1 into a variety of cells induces morphologic changes including the production of long, thin filopodia.


The actual alignment was detected with superfamily member pfam05083:

Pssm-ID: 398655  Cd Length: 78  Bit Score: 92.62  E-value: 8.57e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578811965   7 VKRLERSWhllswsqAQgSSEQELHYASLQRLPVPSSEGPDLRGRDkrGTKEDPRADYACIAENKP 72
Cdd:pfam05083 23 VKRLERNW-------AQ-VSDQELHYASLQRLPVPSSEGPDVGERE--GTKEDPSTDYACIAKNKP 78
 
Name Accession Description Interval E-value
LST1 pfam05083
LST-1 protein; B144/LST1 is a gene encoded in the human major histocompatibility complex that ...
 7-72 8.57e-27

LST-1 protein; B144/LST1 is a gene encoded in the human major histocompatibility complex that produces multiple forms of alternatively spliced mRNA and encodes peptides fewer than 100 amino acids in length. B144/LST1 is strongly expressed in dendritic cells. Transfection of B144/LST1 into a variety of cells induces morphologic changes including the production of long, thin filopodia.


Pssm-ID: 398655  Cd Length: 78  Bit Score: 92.62  E-value: 8.57e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578811965   7 VKRLERSWhllswsqAQgSSEQELHYASLQRLPVPSSEGPDLRGRDkrGTKEDPRADYACIAENKP 72
Cdd:pfam05083 23 VKRLERNW-------AQ-VSDQELHYASLQRLPVPSSEGPDVGERE--GTKEDPSTDYACIAKNKP 78
 
Name Accession Description Interval E-value
LST1 pfam05083
LST-1 protein; B144/LST1 is a gene encoded in the human major histocompatibility complex that ...
 7-72 8.57e-27

LST-1 protein; B144/LST1 is a gene encoded in the human major histocompatibility complex that produces multiple forms of alternatively spliced mRNA and encodes peptides fewer than 100 amino acids in length. B144/LST1 is strongly expressed in dendritic cells. Transfection of B144/LST1 into a variety of cells induces morphologic changes including the production of long, thin filopodia.


Pssm-ID: 398655  Cd Length: 78  Bit Score: 92.62  E-value: 8.57e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578811965   7 VKRLERSWhllswsqAQgSSEQELHYASLQRLPVPSSEGPDLRGRDkrGTKEDPRADYACIAENKP 72
Cdd:pfam05083 23 VKRLERNW-------AQ-VSDQELHYASLQRLPVPSSEGPDVGERE--GTKEDPSTDYACIAKNKP 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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