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Conserved domains on  [gi|568926518|ref|XP_006537898|]
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mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 isoform X1 [Mus musculus]

Protein Classification

solute carrier family 25 protein( domain architecture ID 1000144)

solute carrier family 25 (SLC25) protein which transfers molecules across the membranes of organelles, usually mitochondria

Gene Ontology:  GO:0006839
PubMed:  23266187

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Mito_carr super family cl37969
Mitochondrial carrier protein;
31-112 4.48e-09

Mitochondrial carrier protein;


The actual alignment was detected with superfamily member pfam00153:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 52.66  E-value: 4.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518   31 MKHYLCGYCAAFNNVAITYPVQKILFRQQL-------YGIKTRDAVLQL-RKDGFRNLYRGILPPLMQKTTTLALMFGLY 102
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVqggsgksKGRGILDCFKKIyKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
                          90
                  ....*....|
gi 568926518  103 EDLSRLLHKH 112
Cdd:pfam00153  86 ETLKRLLLKK 95
Mito_carr super family cl37969
Mitochondrial carrier protein;
119-204 3.41e-07

Mitochondrial carrier protein;


The actual alignment was detected with superfamily member pfam00153:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 47.65  E-value: 3.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  119 FATRSVAALLAGTTEAILT-PFERVQTLLQ--DHKHHDKFTNTYQAFR-ALRCHGIAEYYRGMVPILFRNGFGNVLFFGL 194
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTyPLDVVKTRLQvqGGSGKSKGRGILDCFKkIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84
                          90
                  ....*....|
gi 568926518  195 RGPIKESLPT 204
Cdd:pfam00153  85 YETLKRLLLK 94
Mito_carr super family cl37969
Mitochondrial carrier protein;
211-297 1.23e-06

Mitochondrial carrier protein;


The actual alignment was detected with superfamily member pfam00153:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 46.11  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  211 HLVNDFICGGVLGAVLGFLSFPINVVKARIQSQ---IGGPFLSLPMVFKTIWieRDRKLINLFRGAHLNYHRSLISWGII 287
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsGKSKGRGILDCFKKIY--KEEGIRGLYKGLLPNLLRVAPAAAIY 81
                          90
                  ....*....|
gi 568926518  288 NATYEFLLKI 297
Cdd:pfam00153  82 FGTYETLKRL 91
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
31-112 4.48e-09

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 52.66  E-value: 4.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518   31 MKHYLCGYCAAFNNVAITYPVQKILFRQQL-------YGIKTRDAVLQL-RKDGFRNLYRGILPPLMQKTTTLALMFGLY 102
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVqggsgksKGRGILDCFKKIyKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
                          90
                  ....*....|
gi 568926518  103 EDLSRLLHKH 112
Cdd:pfam00153  86 ETLKRLLLKK 95
Mito_carr pfam00153
Mitochondrial carrier protein;
119-204 3.41e-07

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 47.65  E-value: 3.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  119 FATRSVAALLAGTTEAILT-PFERVQTLLQ--DHKHHDKFTNTYQAFR-ALRCHGIAEYYRGMVPILFRNGFGNVLFFGL 194
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTyPLDVVKTRLQvqGGSGKSKGRGILDCFKkIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84
                          90
                  ....*....|
gi 568926518  195 RGPIKESLPT 204
Cdd:pfam00153  85 YETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
211-297 1.23e-06

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 46.11  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  211 HLVNDFICGGVLGAVLGFLSFPINVVKARIQSQ---IGGPFLSLPMVFKTIWieRDRKLINLFRGAHLNYHRSLISWGII 287
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsGKSKGRGILDCFKKIY--KEEGIRGLYKGLLPNLLRVAPAAAIY 81
                          90
                  ....*....|
gi 568926518  288 NATYEFLLKI 297
Cdd:pfam00153  82 FGTYETLKRL 91
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
78-239 4.25e-04

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 41.06  E-value: 4.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  78 RNLYRGILPPLMQKTTTLALMFGLYEDLSRLLHKHVSSAPEFATRSVAALLAGTTEAIL-TPFERVQTLLQDHKHHDKFT 156
Cdd:PTZ00168  43 KKLYSGILPTLVGTVPASAFFYCFYELSKKLLTEYRENISKTNLYLISTSIAEITACIVrLPFEIVKQNMQVSGNISVLK 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518 157 NTYQAFR--ALRCHGIAEYYrgmVPILFRNGFGNVLFF---GLR-------GPIKESLPTATTYsahlvndfICGGVLGA 224
Cdd:PTZ00168 123 TIYEITQreGLPSFLGKSYF---VMIVREIPFDCIQYFlweTLKekakkdfGKFSKKYPSITSA--------ICGGLAGG 191
                        170
                 ....*....|....*
gi 568926518 225 VLGFLSFPINVVKAR 239
Cdd:PTZ00168 192 IAGFLTTPVDVIKSR 206
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
31-112 4.48e-09

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 52.66  E-value: 4.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518   31 MKHYLCGYCAAFNNVAITYPVQKILFRQQL-------YGIKTRDAVLQL-RKDGFRNLYRGILPPLMQKTTTLALMFGLY 102
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVqggsgksKGRGILDCFKKIyKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
                          90
                  ....*....|
gi 568926518  103 EDLSRLLHKH 112
Cdd:pfam00153  86 ETLKRLLLKK 95
Mito_carr pfam00153
Mitochondrial carrier protein;
119-204 3.41e-07

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 47.65  E-value: 3.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  119 FATRSVAALLAGTTEAILT-PFERVQTLLQ--DHKHHDKFTNTYQAFR-ALRCHGIAEYYRGMVPILFRNGFGNVLFFGL 194
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTyPLDVVKTRLQvqGGSGKSKGRGILDCFKkIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84
                          90
                  ....*....|
gi 568926518  195 RGPIKESLPT 204
Cdd:pfam00153  85 YETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
211-297 1.23e-06

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 46.11  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  211 HLVNDFICGGVLGAVLGFLSFPINVVKARIQSQ---IGGPFLSLPMVFKTIWieRDRKLINLFRGAHLNYHRSLISWGII 287
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsGKSKGRGILDCFKKIY--KEEGIRGLYKGLLPNLLRVAPAAAIY 81
                          90
                  ....*....|
gi 568926518  288 NATYEFLLKI 297
Cdd:pfam00153  82 FGTYETLKRL 91
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
78-239 4.25e-04

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 41.06  E-value: 4.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518  78 RNLYRGILPPLMQKTTTLALMFGLYEDLSRLLHKHVSSAPEFATRSVAALLAGTTEAIL-TPFERVQTLLQDHKHHDKFT 156
Cdd:PTZ00168  43 KKLYSGILPTLVGTVPASAFFYCFYELSKKLLTEYRENISKTNLYLISTSIAEITACIVrLPFEIVKQNMQVSGNISVLK 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926518 157 NTYQAFR--ALRCHGIAEYYrgmVPILFRNGFGNVLFF---GLR-------GPIKESLPTATTYsahlvndfICGGVLGA 224
Cdd:PTZ00168 123 TIYEITQreGLPSFLGKSYF---VMIVREIPFDCIQYFlweTLKekakkdfGKFSKKYPSITSA--------ICGGLAGG 191
                        170
                 ....*....|....*
gi 568926518 225 VLGFLSFPINVVKAR 239
Cdd:PTZ00168 192 IAGFLTTPVDVIKSR 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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