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Conserved domains on  [gi|568976016|ref|XP_006534375|]
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bridge-like lipid transfer protein family member 2 isoform X1 [Mus musculus]

Protein Classification

Fmp27_GFWDK and Apt1 domain-containing protein( domain architecture ID 10300330)

protein containing domains Fmp27, Fmp27_GFWDK, and Apt1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Apt1 pfam10351
Golgi-body localization protein domain; This is the C-terminus of a family of proteins ...
1560-2033 8.31e-127

Golgi-body localization protein domain; This is the C-terminus of a family of proteins conserved from plants to humans. The plant members are localized to the Golgi proteins and appear to regulate membrane trafficking, as they are required for rapid vesicle accumulation at the tip of the pollen tube. The C-terminus probably contains the Golgi localization signal and it is well-conserved.


:

Pssm-ID: 463055  Cd Length: 466  Bit Score: 407.80  E-value: 8.31e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1560 IISRCNCRMYYISYSH-DIDPELATQIKPPEvhenqekedllkkQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLL 1638
Cdd:pfam10351    1 VVERTSMSLRYDKYNPlRLKLNDESVSTPLE-------------DESRMDELTVDFPKLVATANSSQYYALYDIVTDLLL 67
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1639 HVEPKRKEHSEKKQRVRFQlEISSNPEEQRSSILHLQEAVRQhvaqirhlekqMYSIMKSLQddsKNENLLD-LNQKLQL 1717
Cdd:pfam10351   68 YSEPKEKERSEKLEKLMLA-SDFSDLEGLDEMVKKLQERIRQ-----------LEEIKLNFQ---LRDDYLDdEGLEDLL 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1718 QLNQEKANLQlesEELNILIRCFKDFQLQRANKmelrkQQEDVSVVRRTEFYFAQARWRLTEEDGQlGIAELELQRFLYS 1797
Cdd:pfam10351  133 LLEKELAECK---EELFLLMKAIKTSQLRKGES-----KDSSKSSALRWSISADEIIWHLLDDDGE-PFADLALANSSYD 203
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1798 KVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQ----SSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQ 1873
Cdd:pfam10351  204 RTDNSDGSNSNRLEIGSLQGFNLLPNAIYPELLSPYedpgDSPEDGRKPMLRVFWKMLPPVGGIPVVEHFEVNLQPLKIQ 283
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1874 LSHRFFHRMMGFFFPGRNVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGSGKGVAQGLTRSSGVRRSFRK--- 1950
Cdd:pfam10351  284 LEHETGKKLMEYIFPKRDSDSQENEASVKSDDDDDSDDSSSSSSSSSSTSSSSSSSSSSSSSSSLELRSSTSSSSSSels 363
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1951 ------------------LPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKG--EKNSVDWGDLNLVLPCLEYHNN 2010
Cdd:pfam10351  364 sssssskssseedslessASERASDDLEEMKSRASKYMTFIYIKIPSVVLCLSYKGkkEKNLEDVHDLVFRLPTLEYRNK 443
                          490       500
                   ....*....|....*....|...
gi 568976016  2011 TWTWLDFAMAVKRDSRKALVAQV 2033
Cdd:pfam10351  444 TWSWLDLALALKKDVIKALLSHT 466
Fmp27 super family cl11012
Mitochondrial protein from FMP27; This family contains mitochondrial FMP27 proteins which in ...
1-531 2.21e-52

Mitochondrial protein from FMP27; This family contains mitochondrial FMP27 proteins which in yeasts together with SEN1 are long genes that exist in a looped conformation, effectively bringing together their promoter and terminator regions. Pol-II is located at both ends of FMP27 when this gene is transcribed from a GAL1 promoter under induced and non-induced conditions. The exact function of the Fmp27 protein is not certain.


The actual alignment was detected with superfamily member pfam10344:

Pssm-ID: 431223  Cd Length: 865  Bit Score: 200.76  E-value: 2.21e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016     1 MVLKVATSESLWHIQISRSRFLLDSDGKSLICKVNLS-----KINSKVLKSGQLEDTCLVELSLALDLRLQVSVS-SWHL 74
Cdd:pfam10344  125 HIFNTTVHDLDVGITQIGSLSLTVDERRKMVDRESEKaefiiNLRNVLFTVDGNEAEILDHCTLNLHGKLSKDLPgGLRD 204
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016    75 TAVTVDVWTLHAELHegLFHSQLLCHAPGRISKSVS------------------CSDLTENFAEPTLPGLYLLQRLPDQV 136
Cdd:pfam10344  205 LAISLKLGRLHIPLD--DLMSLVAQLKKSKESKPEPsvkneevpevsleeleepKSEKTVQKVESSLDLVSSLLRLISEI 282
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   137 KVKMENTSVVLSMNSQKRHLT-----WTLKLLHFLYHRDEDQLPLRS--FTANyDMAQMSTELLLE---DGLLLSQSRQR 206
Cdd:pfam10344  283 QIKVENFGLTDIPFSSKDDLSsvslyVSSKEVGFNLHRLDKKSPGFKmlFDPD-DVPHQALLALTSlkvSLDDNSHSPDR 361
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   207 IVCLNSLKANVQVT----------------TIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSPDLKQRKK---- 266
Cdd:pfam10344  362 ILEIPSATFTGKTNllskssdddvtaeefnNNILELNLTLTSPSIDLDHEQLSLLLSLLKNIKLLKSSPSLKKKKSrril 441
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   267 -----RTFPQIL--------------------APIIFSTSVSNVSISIQLGD--TPPFALGFNSI--------------- 304
Cdd:pfam10344  442 hsllsRYLPKVNlkfsieepvirihlpnpsksKFDLLISSISVLSFDLESSHssESELHYSFITYlrlsshqlyyqnpkg 521
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   305 ---------------------------SLDYQHLRPQSIHQRAVLTVDHLCWRVGS------------------------ 333
Cdd:pfam10344  522 skhnilkldsielkvalnllpnlkvklSGSLNTLSLDLSNLEILLGINDVVRQLRRqvrnrlnlgveneyfndiynefrs 601
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   334 --------------DSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSNTlfLDCTIRGLQVEISDICAQCL 399
Cdd:pfam10344  602 rleeseeqestplkEKLFRRLPSWLLSIKFELSSLSLDLGSRSVLIPKDIYDSTLDDS--VSDFIRGVSIKLRKLSFEYK 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   400 SRVLSLVIPQSERSAVSRKSSLGESVTLL--------------------------------------WKVDLKVEDMNLF 441
Cdd:pfam10344  680 NLKLSLGNNVRSIRRFTLSSSAGESDSDDdsppresdsglsdgstldstssglegeviesddklesePFLSLPVFDIKVS 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   442 TLSALVGA-SELRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLS---------------MLS 505
Cdd:pfam10344  760 TLSDDLGPiLHLNLHIDKIDGQYSLYRLFCVIYALSLLKSFFGKPISTIKRPSTKDEIQELSkslkkpkfdwkglkeLLT 839
                          730       740
                   ....*....|....*....|....*.
gi 568976016   506 LTYHSSIRSLEVQCGAGLTLLWSPPD 531
Cdd:pfam10344  840 VDVKVKSVAVVVRLPNDVPLLLEIFG 865
Fmp27_GFWDK pfam10347
RNA pol II promoter Fmp27 protein domain; Fmp27_GFWDK is a conserved domain of a family of ...
885-1017 1.05e-47

RNA pol II promoter Fmp27 protein domain; Fmp27_GFWDK is a conserved domain of a family of proteins involved in RNA polymerase II transcription initiation. It contains characteriztic GFWDK sequence motifs. Some members are associated with domain Fmp27_SW (pfam10305) towards the N terminus.


:

Pssm-ID: 402113  Cd Length: 155  Bit Score: 167.83  E-value: 1.05e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   885 DYPRYLFEIR--------DWRLMGRLAGTEQSGQ-PCSRRRQILHL--------GLPWGNVAVERNMPPLKFYHDFHSEI 947
Cdd:pfam10347    1 DYPLPLVHFPpnqspslpALHLKGDLVIAEQLVTsEESLRRIFVPLvpsaitenGDSFYSVTVPRTLTPVKFYSDLNIDI 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976016   948 FQ---YTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQ--ANLHQLATEDPYNT 1017
Cdd:pfam10347   81 NSdrpTRITWGKSYQPAIQQVMLAFDNFTKPPVDPSPKLGFWDKIRLIFHGRISFNWKNgdFHLHLKGSRDPYDI 155
 
Name Accession Description Interval E-value
Apt1 pfam10351
Golgi-body localization protein domain; This is the C-terminus of a family of proteins ...
1560-2033 8.31e-127

Golgi-body localization protein domain; This is the C-terminus of a family of proteins conserved from plants to humans. The plant members are localized to the Golgi proteins and appear to regulate membrane trafficking, as they are required for rapid vesicle accumulation at the tip of the pollen tube. The C-terminus probably contains the Golgi localization signal and it is well-conserved.


Pssm-ID: 463055  Cd Length: 466  Bit Score: 407.80  E-value: 8.31e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1560 IISRCNCRMYYISYSH-DIDPELATQIKPPEvhenqekedllkkQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLL 1638
Cdd:pfam10351    1 VVERTSMSLRYDKYNPlRLKLNDESVSTPLE-------------DESRMDELTVDFPKLVATANSSQYYALYDIVTDLLL 67
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1639 HVEPKRKEHSEKKQRVRFQlEISSNPEEQRSSILHLQEAVRQhvaqirhlekqMYSIMKSLQddsKNENLLD-LNQKLQL 1717
Cdd:pfam10351   68 YSEPKEKERSEKLEKLMLA-SDFSDLEGLDEMVKKLQERIRQ-----------LEEIKLNFQ---LRDDYLDdEGLEDLL 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1718 QLNQEKANLQlesEELNILIRCFKDFQLQRANKmelrkQQEDVSVVRRTEFYFAQARWRLTEEDGQlGIAELELQRFLYS 1797
Cdd:pfam10351  133 LLEKELAECK---EELFLLMKAIKTSQLRKGES-----KDSSKSSALRWSISADEIIWHLLDDDGE-PFADLALANSSYD 203
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1798 KVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQ----SSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQ 1873
Cdd:pfam10351  204 RTDNSDGSNSNRLEIGSLQGFNLLPNAIYPELLSPYedpgDSPEDGRKPMLRVFWKMLPPVGGIPVVEHFEVNLQPLKIQ 283
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1874 LSHRFFHRMMGFFFPGRNVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGSGKGVAQGLTRSSGVRRSFRK--- 1950
Cdd:pfam10351  284 LEHETGKKLMEYIFPKRDSDSQENEASVKSDDDDDSDDSSSSSSSSSSTSSSSSSSSSSSSSSSLELRSSTSSSSSSels 363
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1951 ------------------LPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKG--EKNSVDWGDLNLVLPCLEYHNN 2010
Cdd:pfam10351  364 sssssskssseedslessASERASDDLEEMKSRASKYMTFIYIKIPSVVLCLSYKGkkEKNLEDVHDLVFRLPTLEYRNK 443
                          490       500
                   ....*....|....*....|...
gi 568976016  2011 TWTWLDFAMAVKRDSRKALVAQV 2033
Cdd:pfam10351  444 TWSWLDLALALKKDVIKALLSHT 466
Fmp27 pfam10344
Mitochondrial protein from FMP27; This family contains mitochondrial FMP27 proteins which in ...
1-531 2.21e-52

Mitochondrial protein from FMP27; This family contains mitochondrial FMP27 proteins which in yeasts together with SEN1 are long genes that exist in a looped conformation, effectively bringing together their promoter and terminator regions. Pol-II is located at both ends of FMP27 when this gene is transcribed from a GAL1 promoter under induced and non-induced conditions. The exact function of the Fmp27 protein is not certain.


Pssm-ID: 431223  Cd Length: 865  Bit Score: 200.76  E-value: 2.21e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016     1 MVLKVATSESLWHIQISRSRFLLDSDGKSLICKVNLS-----KINSKVLKSGQLEDTCLVELSLALDLRLQVSVS-SWHL 74
Cdd:pfam10344  125 HIFNTTVHDLDVGITQIGSLSLTVDERRKMVDRESEKaefiiNLRNVLFTVDGNEAEILDHCTLNLHGKLSKDLPgGLRD 204
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016    75 TAVTVDVWTLHAELHegLFHSQLLCHAPGRISKSVS------------------CSDLTENFAEPTLPGLYLLQRLPDQV 136
Cdd:pfam10344  205 LAISLKLGRLHIPLD--DLMSLVAQLKKSKESKPEPsvkneevpevsleeleepKSEKTVQKVESSLDLVSSLLRLISEI 282
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   137 KVKMENTSVVLSMNSQKRHLT-----WTLKLLHFLYHRDEDQLPLRS--FTANyDMAQMSTELLLE---DGLLLSQSRQR 206
Cdd:pfam10344  283 QIKVENFGLTDIPFSSKDDLSsvslyVSSKEVGFNLHRLDKKSPGFKmlFDPD-DVPHQALLALTSlkvSLDDNSHSPDR 361
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   207 IVCLNSLKANVQVT----------------TIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSPDLKQRKK---- 266
Cdd:pfam10344  362 ILEIPSATFTGKTNllskssdddvtaeefnNNILELNLTLTSPSIDLDHEQLSLLLSLLKNIKLLKSSPSLKKKKSrril 441
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   267 -----RTFPQIL--------------------APIIFSTSVSNVSISIQLGD--TPPFALGFNSI--------------- 304
Cdd:pfam10344  442 hsllsRYLPKVNlkfsieepvirihlpnpsksKFDLLISSISVLSFDLESSHssESELHYSFITYlrlsshqlyyqnpkg 521
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   305 ---------------------------SLDYQHLRPQSIHQRAVLTVDHLCWRVGS------------------------ 333
Cdd:pfam10344  522 skhnilkldsielkvalnllpnlkvklSGSLNTLSLDLSNLEILLGINDVVRQLRRqvrnrlnlgveneyfndiynefrs 601
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   334 --------------DSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSNTlfLDCTIRGLQVEISDICAQCL 399
Cdd:pfam10344  602 rleeseeqestplkEKLFRRLPSWLLSIKFELSSLSLDLGSRSVLIPKDIYDSTLDDS--VSDFIRGVSIKLRKLSFEYK 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   400 SRVLSLVIPQSERSAVSRKSSLGESVTLL--------------------------------------WKVDLKVEDMNLF 441
Cdd:pfam10344  680 NLKLSLGNNVRSIRRFTLSSSAGESDSDDdsppresdsglsdgstldstssglegeviesddklesePFLSLPVFDIKVS 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   442 TLSALVGA-SELRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLS---------------MLS 505
Cdd:pfam10344  760 TLSDDLGPiLHLNLHIDKIDGQYSLYRLFCVIYALSLLKSFFGKPISTIKRPSTKDEIQELSkslkkpkfdwkglkeLLT 839
                          730       740
                   ....*....|....*....|....*.
gi 568976016   506 LTYHSSIRSLEVQCGAGLTLLWSPPD 531
Cdd:pfam10344  840 VDVKVKSVAVVVRLPNDVPLLLEIFG 865
Fmp27_GFWDK pfam10347
RNA pol II promoter Fmp27 protein domain; Fmp27_GFWDK is a conserved domain of a family of ...
885-1017 1.05e-47

RNA pol II promoter Fmp27 protein domain; Fmp27_GFWDK is a conserved domain of a family of proteins involved in RNA polymerase II transcription initiation. It contains characteriztic GFWDK sequence motifs. Some members are associated with domain Fmp27_SW (pfam10305) towards the N terminus.


Pssm-ID: 402113  Cd Length: 155  Bit Score: 167.83  E-value: 1.05e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   885 DYPRYLFEIR--------DWRLMGRLAGTEQSGQ-PCSRRRQILHL--------GLPWGNVAVERNMPPLKFYHDFHSEI 947
Cdd:pfam10347    1 DYPLPLVHFPpnqspslpALHLKGDLVIAEQLVTsEESLRRIFVPLvpsaitenGDSFYSVTVPRTLTPVKFYSDLNIDI 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976016   948 FQ---YTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQ--ANLHQLATEDPYNT 1017
Cdd:pfam10347   81 NSdrpTRITWGKSYQPAIQQVMLAFDNFTKPPVDPSPKLGFWDKIRLIFHGRISFNWKNgdFHLHLKGSRDPYDI 155
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1618-1812 4.44e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1618 EISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRfQL-----EISSNPEEQRSSILHLQEAVRQHVAQIRHLEKQM 1692
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELE-QLrkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1693 YS----IMKSLQDDSKNENLL----DLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVR 1764
Cdd:TIGR02168  757 TEleaeIEELEERLEEAEEELaeaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 568976016  1765 RTEFYFAQARWRLTEEDgqlgIAELELQRF-LYSKVNKSDDTAEHLLEL 1812
Cdd:TIGR02168  837 ERRLEDLEEQIEELSED----IESLAAEIEeLEELIEELESELEALLNE 881
 
Name Accession Description Interval E-value
Apt1 pfam10351
Golgi-body localization protein domain; This is the C-terminus of a family of proteins ...
1560-2033 8.31e-127

Golgi-body localization protein domain; This is the C-terminus of a family of proteins conserved from plants to humans. The plant members are localized to the Golgi proteins and appear to regulate membrane trafficking, as they are required for rapid vesicle accumulation at the tip of the pollen tube. The C-terminus probably contains the Golgi localization signal and it is well-conserved.


Pssm-ID: 463055  Cd Length: 466  Bit Score: 407.80  E-value: 8.31e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1560 IISRCNCRMYYISYSH-DIDPELATQIKPPEvhenqekedllkkQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLL 1638
Cdd:pfam10351    1 VVERTSMSLRYDKYNPlRLKLNDESVSTPLE-------------DESRMDELTVDFPKLVATANSSQYYALYDIVTDLLL 67
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1639 HVEPKRKEHSEKKQRVRFQlEISSNPEEQRSSILHLQEAVRQhvaqirhlekqMYSIMKSLQddsKNENLLD-LNQKLQL 1717
Cdd:pfam10351   68 YSEPKEKERSEKLEKLMLA-SDFSDLEGLDEMVKKLQERIRQ-----------LEEIKLNFQ---LRDDYLDdEGLEDLL 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1718 QLNQEKANLQlesEELNILIRCFKDFQLQRANKmelrkQQEDVSVVRRTEFYFAQARWRLTEEDGQlGIAELELQRFLYS 1797
Cdd:pfam10351  133 LLEKELAECK---EELFLLMKAIKTSQLRKGES-----KDSSKSSALRWSISADEIIWHLLDDDGE-PFADLALANSSYD 203
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1798 KVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQ----SSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQ 1873
Cdd:pfam10351  204 RTDNSDGSNSNRLEIGSLQGFNLLPNAIYPELLSPYedpgDSPEDGRKPMLRVFWKMLPPVGGIPVVEHFEVNLQPLKIQ 283
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1874 LSHRFFHRMMGFFFPGRNVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGSGKGVAQGLTRSSGVRRSFRK--- 1950
Cdd:pfam10351  284 LEHETGKKLMEYIFPKRDSDSQENEASVKSDDDDDSDDSSSSSSSSSSTSSSSSSSSSSSSSSSLELRSSTSSSSSSels 363
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1951 ------------------LPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKG--EKNSVDWGDLNLVLPCLEYHNN 2010
Cdd:pfam10351  364 sssssskssseedslessASERASDDLEEMKSRASKYMTFIYIKIPSVVLCLSYKGkkEKNLEDVHDLVFRLPTLEYRNK 443
                          490       500
                   ....*....|....*....|...
gi 568976016  2011 TWTWLDFAMAVKRDSRKALVAQV 2033
Cdd:pfam10351  444 TWSWLDLALALKKDVIKALLSHT 466
Fmp27 pfam10344
Mitochondrial protein from FMP27; This family contains mitochondrial FMP27 proteins which in ...
1-531 2.21e-52

Mitochondrial protein from FMP27; This family contains mitochondrial FMP27 proteins which in yeasts together with SEN1 are long genes that exist in a looped conformation, effectively bringing together their promoter and terminator regions. Pol-II is located at both ends of FMP27 when this gene is transcribed from a GAL1 promoter under induced and non-induced conditions. The exact function of the Fmp27 protein is not certain.


Pssm-ID: 431223  Cd Length: 865  Bit Score: 200.76  E-value: 2.21e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016     1 MVLKVATSESLWHIQISRSRFLLDSDGKSLICKVNLS-----KINSKVLKSGQLEDTCLVELSLALDLRLQVSVS-SWHL 74
Cdd:pfam10344  125 HIFNTTVHDLDVGITQIGSLSLTVDERRKMVDRESEKaefiiNLRNVLFTVDGNEAEILDHCTLNLHGKLSKDLPgGLRD 204
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016    75 TAVTVDVWTLHAELHegLFHSQLLCHAPGRISKSVS------------------CSDLTENFAEPTLPGLYLLQRLPDQV 136
Cdd:pfam10344  205 LAISLKLGRLHIPLD--DLMSLVAQLKKSKESKPEPsvkneevpevsleeleepKSEKTVQKVESSLDLVSSLLRLISEI 282
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   137 KVKMENTSVVLSMNSQKRHLT-----WTLKLLHFLYHRDEDQLPLRS--FTANyDMAQMSTELLLE---DGLLLSQSRQR 206
Cdd:pfam10344  283 QIKVENFGLTDIPFSSKDDLSsvslyVSSKEVGFNLHRLDKKSPGFKmlFDPD-DVPHQALLALTSlkvSLDDNSHSPDR 361
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   207 IVCLNSLKANVQVT----------------TIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSPDLKQRKK---- 266
Cdd:pfam10344  362 ILEIPSATFTGKTNllskssdddvtaeefnNNILELNLTLTSPSIDLDHEQLSLLLSLLKNIKLLKSSPSLKKKKSrril 441
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   267 -----RTFPQIL--------------------APIIFSTSVSNVSISIQLGD--TPPFALGFNSI--------------- 304
Cdd:pfam10344  442 hsllsRYLPKVNlkfsieepvirihlpnpsksKFDLLISSISVLSFDLESSHssESELHYSFITYlrlsshqlyyqnpkg 521
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   305 ---------------------------SLDYQHLRPQSIHQRAVLTVDHLCWRVGS------------------------ 333
Cdd:pfam10344  522 skhnilkldsielkvalnllpnlkvklSGSLNTLSLDLSNLEILLGINDVVRQLRRqvrnrlnlgveneyfndiynefrs 601
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   334 --------------DSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSNTlfLDCTIRGLQVEISDICAQCL 399
Cdd:pfam10344  602 rleeseeqestplkEKLFRRLPSWLLSIKFELSSLSLDLGSRSVLIPKDIYDSTLDDS--VSDFIRGVSIKLRKLSFEYK 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   400 SRVLSLVIPQSERSAVSRKSSLGESVTLL--------------------------------------WKVDLKVEDMNLF 441
Cdd:pfam10344  680 NLKLSLGNNVRSIRRFTLSSSAGESDSDDdsppresdsglsdgstldstssglegeviesddklesePFLSLPVFDIKVS 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   442 TLSALVGA-SELRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLS---------------MLS 505
Cdd:pfam10344  760 TLSDDLGPiLHLNLHIDKIDGQYSLYRLFCVIYALSLLKSFFGKPISTIKRPSTKDEIQELSkslkkpkfdwkglkeLLT 839
                          730       740
                   ....*....|....*....|....*.
gi 568976016   506 LTYHSSIRSLEVQCGAGLTLLWSPPD 531
Cdd:pfam10344  840 VDVKVKSVAVVVRLPNDVPLLLEIFG 865
Fmp27_GFWDK pfam10347
RNA pol II promoter Fmp27 protein domain; Fmp27_GFWDK is a conserved domain of a family of ...
885-1017 1.05e-47

RNA pol II promoter Fmp27 protein domain; Fmp27_GFWDK is a conserved domain of a family of proteins involved in RNA polymerase II transcription initiation. It contains characteriztic GFWDK sequence motifs. Some members are associated with domain Fmp27_SW (pfam10305) towards the N terminus.


Pssm-ID: 402113  Cd Length: 155  Bit Score: 167.83  E-value: 1.05e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016   885 DYPRYLFEIR--------DWRLMGRLAGTEQSGQ-PCSRRRQILHL--------GLPWGNVAVERNMPPLKFYHDFHSEI 947
Cdd:pfam10347    1 DYPLPLVHFPpnqspslpALHLKGDLVIAEQLVTsEESLRRIFVPLvpsaitenGDSFYSVTVPRTLTPVKFYSDLNIDI 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976016   948 FQ---YTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQ--ANLHQLATEDPYNT 1017
Cdd:pfam10347   81 NSdrpTRITWGKSYQPAIQQVMLAFDNFTKPPVDPSPKLGFWDKIRLIFHGRISFNWKNgdFHLHLKGSRDPYDI 155
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
1637-1793 2.26e-06

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 52.65  E-value: 2.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1637 LLHVEPKRKEHSEKKQRVRFQLEISSNPEEQrssiLHLQEavRQHVAQIRhLEKQmysimkSLQDDSKNENLLDLNQKLQ 1716
Cdd:pfam15709  347 RLEVERKRREQEEQRRLQQEQLERAEKMREE----LELEQ--QRRFEEIR-LRKQ------RLEEERQRQEEEERKQRLQ 413
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1717 LQLNQEKANLQleSEELNILIRcfkdfQLQRankmelRKQQEDVSVVRRTEFYFAQARWRLTEEDGQL-GIAE---LELQ 1792
Cdd:pfam15709  414 LQAAQERARQQ--QEEFRRKLQ-----ELQR------KKQQEEAERAEAEKQRQKELEMQLAEEQKRLmEMAEeerLEYQ 480

                   .
gi 568976016  1793 R 1793
Cdd:pfam15709  481 R 481
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1618-1812 4.44e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1618 EISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRfQL-----EISSNPEEQRSSILHLQEAVRQHVAQIRHLEKQM 1692
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELE-QLrkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976016  1693 YS----IMKSLQDDSKNENLL----DLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVR 1764
Cdd:TIGR02168  757 TEleaeIEELEERLEEAEEELaeaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 568976016  1765 RTEFYFAQARWRLTEEDgqlgIAELELQRF-LYSKVNKSDDTAEHLLEL 1812
Cdd:TIGR02168  837 ERRLEDLEEQIEELSED----IESLAAEIEeLEELIEELESELEALLNE 881
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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