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Conserved domains on  [gi|568937382|ref|XP_006530478|]
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CAP-Gly domain-containing linker protein 1 isoform X7 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.66e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.66e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.21e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.21e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 976-1873 1.93e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.93e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   976 QDLKAKYEKAS--SETKTKHEEILQNLqkmlADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSA 1045
Cdd:TIGR02168  155 EERRAIFEEAAgiSKYKERRKETERKL----ERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1046 KKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKR 1125
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1126 YQQEHRDRESLVAEREKLLKEINAAQEELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkk 1205
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEEL--------------AELEEKLEELKEELESLEAELEELEAELEELESR--- 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1206 ltaenlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENllQTNRDLQFEKD 1285
Cdd:TIGR02168  374 --------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELE 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1286 TLRQGQEKLSASLEAtlqvkqlLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqll 1365
Cdd:TIGR02168  444 ELEEELEELQEELER-------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----------------- 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1366 hEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLL 1439
Cdd:TIGR02168  500 -NLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPL 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1440 KEKSALELQ-NGDLLADRESSIKTIGDLRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDL 1515
Cdd:TIGR02168  579 DSIKGTEIQgNDREILKNIEGFLGVAKDLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDG 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1516 SLLLKEAQDAKKNLEKEHTsmIQAKDNlnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESET 1595
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSS--ILERRR---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEE 723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1596 SLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSK 1675
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1676 SKLELQELHSCLTKILDDLRLNHEVALTERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEIS 1748
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERA 883

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1749 QLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLE 1819
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKI 963

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568937382  1820 DTKQTNAR-----LQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQA 1873
Cdd:TIGR02168  964 EDDEEEARrrlkrLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 606-1276 2.11e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.11e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   606 SAEFAELKTQIERLRLdYQHEIESLQSKQDSERSAHAKEMETMQAKLMkIIKEKEDSLEAVKARLDSAEDQHLVEMEDTL 685
Cdd:TIGR02168  259 TAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   686 NKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDA----LRKANSEGKLELETLRQQLEGAEKQIKNLE 761
Cdd:TIGR02168  337 EELAELE---EKLEELKEELESLEAELEELEAELEELESRLEELEEqletLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   762 TERNAESSKANSITKELQEKELVLtgLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 841
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   842 NVLSSELEKLRENLTDMEAKFKEKDDRED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSV 911
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   912 EELQLKLTKANENAsfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE-LEKKMETSYNQCQDLKAKY-------- 982
Cdd:TIGR02168  572 RVTFLPLDSIKGTE--IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlGGVLVVDDLDNALELAKKLrpgyrivt 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   983 -----------------EKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAK-------- 1036
Cdd:TIGR02168  650 ldgdlvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELeelsrqis 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1037 SLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVS 1116
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1117 EEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELrfckdklmamsekaRAEK 1196
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL--------------ESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1197 EHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQT 1276
Cdd:TIGR02168  876 EALLNERASLEEA-----------LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
353-853 2.96e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 2.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  353 QEALKEKQQhIEQLLAERDLeRAEVAKATSHVGEIEQELALARDGHDQHVLEL-EAKMDQLRTMVEAADREKVELLNQLE 431
Cdd:COG4913   242 EALEDAREQ-IELLEPIREL-AERYAAARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLEAELERLEARLD 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  432 EEKRKVEDLQFRVEEES-ITKGDLEvatvsekSRIMELEKDLALRAQEVAELRRRLES--SKPPGDVDMSLSLLQEISAL 508
Cdd:COG4913   320 ALREELDELEAQIRGNGgDRLEQLE-------REIERLERELEERERRRARLEALLAAlgLPLPASAEEFAALRAEAAAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  509 QEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALhtateklSKENESLRSkldhaNKEN--SDVIALwKSKLETAIAS 586
Cdd:COG4913   393 LEALEEELEALEEALAEAE----AALRDLRRELREL-------EAEIASLER-----RKSNipARLLAL-RDALAEALGL 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  587 HQQAM----EELKVSFSKGIGTDSAE----------------FAELKTQIERL----RLDYQH-------------EIES 629
Cdd:COG4913   456 DEAELpfvgELIEVRPEEERWRGAIErvlggfaltllvppehYAAALRWVNRLhlrgRLVYERvrtglpdperprlDPDS 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  630 LQSKQDSERSAHAKEMETMQAKLMKIIK-EKEDSLE----AV-------------------------------KARLDSA 673
Cdd:COG4913   536 LAGKLDFKPHPFRAWLEAELGRRFDYVCvDSPEELRrhprAItragqvkgngtrhekddrrrirsryvlgfdnRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  674 EDQhLVEMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETLR 747
Cdd:COG4913   616 EAE-LAELEEELAEAEER---LEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  748 QQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTRm 827
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR- 768

                         570       580
                  ....*....|....*....|....*.
gi 568937382  828 QDTVNKLHQKEEQFNVLSSELEKLRE 853
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMR 794
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2134-2150 1.56e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.56e-07
                           10
                   ....*....|....*..
gi 568937382  2134 RPYCEICEMFGHWATNC 2150
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
1716-2092 2.71e-07

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1716 LAEKREMMLRNEEALKEKEKLEESYFILQkeiSQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1795
Cdd:COG5022   805 LLGSRKEYRSYLACIIKLQKTIKREKKLR---ETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELA- 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1796 taedamqimEQMTKEKTETLASLEDTKQTNARLQNEL---------DTLKENNLKTvEELNKSKELL---SVENQKMEEF 1863
Cdd:COG5022   881 ---------ERQLQELKIDVKSISSLKLVNLELESEIielkkslssDLIENLEFKT-ELIARLKKLLnniDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1864 KK-----EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLR------ 1932
Cdd:COG5022   951 VKlpelnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEvaelqs 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1933 ESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlk 2011
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV--- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 2012 eNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKK 2091
Cdd:COG5022  1104 -TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRL 1182


                  .
gi 568937382 2092 K 2092
Cdd:COG5022  1183 Y 1183
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2094-2111 1.87e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.87e-04
                           10
                   ....*....|....*...
gi 568937382  2094 RLFCDICDCFDlHDTEDC 2111
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.66e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.66e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.21e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.21e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 5.10e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.44  E-value: 5.10e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382    213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.47e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.47e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 976-1873 1.93e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.93e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   976 QDLKAKYEKAS--SETKTKHEEILQNLqkmlADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSA 1045
Cdd:TIGR02168  155 EERRAIFEEAAgiSKYKERRKETERKL----ERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1046 KKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKR 1125
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1126 YQQEHRDRESLVAEREKLLKEINAAQEELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkk 1205
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEEL--------------AELEEKLEELKEELESLEAELEELEAELEELESR--- 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1206 ltaenlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENllQTNRDLQFEKD 1285
Cdd:TIGR02168  374 --------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELE 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1286 TLRQGQEKLSASLEAtlqvkqlLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqll 1365
Cdd:TIGR02168  444 ELEEELEELQEELER-------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----------------- 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1366 hEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLL 1439
Cdd:TIGR02168  500 -NLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPL 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1440 KEKSALELQ-NGDLLADRESSIKTIGDLRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDL 1515
Cdd:TIGR02168  579 DSIKGTEIQgNDREILKNIEGFLGVAKDLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDG 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1516 SLLLKEAQDAKKNLEKEHTsmIQAKDNlnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESET 1595
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSS--ILERRR---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEE 723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1596 SLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSK 1675
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1676 SKLELQELHSCLTKILDDLRLNHEVALTERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEIS 1748
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERA 883

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1749 QLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLE 1819
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKI 963

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568937382  1820 DTKQTNAR-----LQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQA 1873
Cdd:TIGR02168  964 EDDEEEARrrlkrLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 606-1276 2.11e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.11e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   606 SAEFAELKTQIERLRLdYQHEIESLQSKQDSERSAHAKEMETMQAKLMkIIKEKEDSLEAVKARLDSAEDQHLVEMEDTL 685
Cdd:TIGR02168  259 TAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   686 NKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDA----LRKANSEGKLELETLRQQLEGAEKQIKNLE 761
Cdd:TIGR02168  337 EELAELE---EKLEELKEELESLEAELEELEAELEELESRLEELEEqletLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   762 TERNAESSKANSITKELQEKELVLtgLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 841
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   842 NVLSSELEKLRENLTDMEAKFKEKDDRED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSV 911
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   912 EELQLKLTKANENAsfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE-LEKKMETSYNQCQDLKAKY-------- 982
Cdd:TIGR02168  572 RVTFLPLDSIKGTE--IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlGGVLVVDDLDNALELAKKLrpgyrivt 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   983 -----------------EKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAK-------- 1036
Cdd:TIGR02168  650 ldgdlvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELeelsrqis 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1037 SLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVS 1116
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1117 EEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELrfckdklmamsekaRAEK 1196
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL--------------ESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1197 EHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQT 1276
Cdd:TIGR02168  876 EALLNERASLEEA-----------LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 663-1245 1.39e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  663 LEAVKARLDSAEDqHLVEMEDTLNKLQ-EAEIKVK------ELEVLQAKYteqsevignftsQLSAVKEKLLDLDALRKA 735
Cdd:COG1196   181 LEATEENLERLED-ILGELERQLEPLErQAEKAERyrelkeELKELEAEL------------LLLKLRELEAELEELEAE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  736 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANS-------ITKELQEKELVLTGLQDSLNQVNQVKETLEKELQT 808
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyeLLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  809 LKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 888
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  889 MSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQ--SQQQAARKHEEEKKELEEKLLELEK 966
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELA 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  967 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQ----KMLADTEDKLKAAQEA------NRDLMQDMEELKTQADKAK 1036
Cdd:COG1196   488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLK 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1037 SLT------YLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1110
Cdd:COG1196   568 AAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1111 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckDKLMAMSE 1190
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER---LEEELEEE 724

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568937382 1191 KARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1245
Cdd:COG1196   725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1006-1617 6.31e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 6.31e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1006 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1076
Cdd:COG1196   176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1077 KGSLLSKLIEVETKITLLQEDQQKLwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1156
Cdd:COG1196   255 LEELEAELAELEAELEELRLELEEL-------ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1157 MHMENDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQK 1236
Cdd:COG1196   328 LEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1237 ALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1316
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1317 TQLDcASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEK- 1395
Cdd:COG1196   484 EELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAa 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1396 --LSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADResSIKTIGDLRRKYDQE 1473
Cdd:COG1196   563 ieYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1474 ATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELktcccE 1553
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-----E 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937382 1554 KNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRL 1617
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 613-1318 2.10e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 76.31  E-value: 2.10e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   613 KTQIERLRLDYQHEIESLQSKQDSERSAHAKE-------METMQAKLMKIIKEKeDSLEAVKARLDSAEDQHLVEMEDTL 685
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQkfylrqsVIDLQTKLQEMQMER-DAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   686 NKLQEAE-IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDAL--RKANSEGKLELETLRQQLEGAEKQIKNLET 762
Cdd:pfam15921  152 HELEAAKcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   763 ERNAESSKANSITKELQ--------EKELVLTGLQDslnQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM----QDT 830
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEalksesqnKIELLLQQHQD---RIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQA 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   831 VNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK-DDREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDEL-- 904
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLhk 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   905 RLKERSVEELQLKLTKANENASFLqkSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDlKAKYEK 984
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQR---------------LEALLKAMKSECQG-QMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   985 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1064
Cdd:pfam15921  451 AAIQGKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1065 LYAQEANALKLEKGSLLSKLIEVET-KITLLQEDQqklwsVNETLHLEKERVSEekqvaekRYQQEHRDRESLVAEREKL 1143
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDK-----VIEILRQQIENMTQ-------LVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1144 LKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARAEKEhlegqVKKLTAENLVLVKDKDDVIQ 1222
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAVKD-----IKQERDQLLNEVKTSRNELN 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1223 KLQSAYEELVKDQKALVQEIEDLTTE-KKSAAEKQMSLDNTCLTLK---------------------AERENLLQTNRDL 1280
Cdd:pfam15921  671 SLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmqkqitAKRGQIDALQSKI 750

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 568937382  1281 QF----------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1318
Cdd:pfam15921  751 QFleeamtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1490-2075 6.35e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 74.33  E-value: 6.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1490 NIDALKKELQERKKENQELTSSKCDLslllkeaQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRdglnLQEECQ 1569
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENI-------EELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1570 KLNEEIREIQ-QTLILEKEARAKESETSLYEN--NKLHGRVVLLEEEIQRLRVCsEQLQTENFTLTQEKTNSEQKVEEII 1646
Cdd:PRK03918  235 ELKEEIEELEkELESLEGSKRKLEEKIRELEEriEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1647 KEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEV-ALTERAEVLQDN-KNLLAEKREMML 1724
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRlTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1725 rnEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLEsqsenrtLRKDKSKLTLKIRELETLH--SFTAAQTAEdamq 1802
Cdd:PRK03918  394 --EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHrkELLEEYTAE---- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1803 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE--NNLKTVEELNKSKELLSVEN-QKMEEFKKEIETLKQAAAQKSQ 1879
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1880 QLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESEFR---------KDADEEKASLQK 1949
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1950 SISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQ 2027
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 568937382 2028 AEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2075
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 2.49e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 72.41  E-value: 2.49e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937382  211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 7.50e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.40  E-value: 7.50e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
646-1273 1.99e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.24  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  646 ETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemedtlNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEK 725
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIE--------ELIKEKE---KELEEVLREINEISSELPELREELEKLEKE 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  726 LLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLET---ERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETL 802
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEErieELKKEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  803 EKELQTLKEKFASTSEEAVSAQTRMQDTVNKlhqkeeqfnvlSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENd 882
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEERIKELEEK-----------EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE- 373

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  883 IAEIMKMSGDNSsqLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtlkaeqsqqqaarkheeekkeleekll 962
Cdd:PRK03918  374 LERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE---------------------------- 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  963 elekkMETSYNQCQDLKAKYEKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1041
Cdd:PRK03918  424 -----LKKAIEELKKAKGKCPVCGRELTEEHRkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1042 LTSAkKEIEVMSEELRGLKSEKqlyaQEANALKLEKgsLLSKLIEVETKITLLQEDQQKLwsvnETLHLEKERVSEEKQV 1121
Cdd:PRK03918  499 KELA-EQLKELEEKLKKYNLEE----LEKKAEEYEK--LKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDE 567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1122 AEKRYQQEHRDRESLVAEReklLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLmamsEKARAEKEHLEG 1201
Cdd:PRK03918  568 LEEELAELLKELEELGFES---VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL----DKAFEELAETEK 640

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382 1202 QVKKLTAENLVLVKDKDDviqklqSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1273
Cdd:PRK03918  641 RLEELRKELEELEKKYSE------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1341-2017 5.08e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 64.74  E-value: 5.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1341 SSLTKLLEEIKTCRAITDSEciqlLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGL---NEKITYL 1417
Cdd:pfam05483   81 SKLYKEAEKIKKWKVSIEAE----LKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikeNNATRHL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1418 TSEKEVACQKVAKLKKQQDSLLKEKSALELqngDLLADRESSIKTIGDLRrkydQEATNRRIVMQEKMKL-LGNIDALKK 1496
Cdd:pfam05483  157 CNLLKETCARSAEKTKKYEYEREETRQVYM---DLNNNIEKMILAFEELR----VQAENARLEMHFKLKEdHEKIQHLEE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1497 ELQER--KKENQ---------ELTSSKCDLSLLLKEAQDAKKNLEKEHT-------SMIQAKDNLNAELKTCCCEKNMLL 1558
Cdd:pfam05483  230 EYKKEinDKEKQvsllliqitEKENKMKDLTFLLEESRDKANQLEEKTKlqdenlkELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1559 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEE----EIQRLRVCSEQLQTENFTLtQE 1634
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtEQQRLEKNEDQLKIITMEL-QK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1635 KTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILD-------DLRLNHEVALTERAE 1707
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQarekeihDLEIQLTAIKTSEEH 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1708 VLQDNKNLLAEKREMMLRNEEALKEKEKLeesyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELET 1787
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKL-------LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1788 lhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEI 1867
Cdd:pfam05483  542 ----KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEN 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1868 ETLKQAAAQKSQQLSALQEENVKLAEELGRTRdevtshQKLEEERSVLNNQlLEMKKSLPSNTLRESEFRKDADEEKASL 1947
Cdd:pfam05483  618 KALKKKGSAENKQLNAYEIKVNKLELELASAK------QKFEEIIDNYQKE-IEDKKISEEKLLEEVEKAKAIADEAVKL 690

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382  1948 QKSISL-TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2017
Cdd:pfam05483  691 QKEIDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
353-853 2.96e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 2.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  353 QEALKEKQQhIEQLLAERDLeRAEVAKATSHVGEIEQELALARDGHDQHVLEL-EAKMDQLRTMVEAADREKVELLNQLE 431
Cdd:COG4913   242 EALEDAREQ-IELLEPIREL-AERYAAARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLEAELERLEARLD 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  432 EEKRKVEDLQFRVEEES-ITKGDLEvatvsekSRIMELEKDLALRAQEVAELRRRLES--SKPPGDVDMSLSLLQEISAL 508
Cdd:COG4913   320 ALREELDELEAQIRGNGgDRLEQLE-------REIERLERELEERERRRARLEALLAAlgLPLPASAEEFAALRAEAAAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  509 QEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALhtateklSKENESLRSkldhaNKEN--SDVIALwKSKLETAIAS 586
Cdd:COG4913   393 LEALEEELEALEEALAEAE----AALRDLRRELREL-------EAEIASLER-----RKSNipARLLAL-RDALAEALGL 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  587 HQQAM----EELKVSFSKGIGTDSAE----------------FAELKTQIERL----RLDYQH-------------EIES 629
Cdd:COG4913   456 DEAELpfvgELIEVRPEEERWRGAIErvlggfaltllvppehYAAALRWVNRLhlrgRLVYERvrtglpdperprlDPDS 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  630 LQSKQDSERSAHAKEMETMQAKLMKIIK-EKEDSLE----AV-------------------------------KARLDSA 673
Cdd:COG4913   536 LAGKLDFKPHPFRAWLEAELGRRFDYVCvDSPEELRrhprAItragqvkgngtrhekddrrrirsryvlgfdnRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  674 EDQhLVEMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETLR 747
Cdd:COG4913   616 EAE-LAELEEELAEAEER---LEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  748 QQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTRm 827
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR- 768

                         570       580
                  ....*....|....*....|....*.
gi 568937382  828 QDTVNKLHQKEEQFNVLSSELEKLRE 853
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMR 794
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2134-2150 1.56e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.56e-07
                           10
                   ....*....|....*..
gi 568937382  2134 RPYCEICEMFGHWATNC 2150
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1716-2092 2.71e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1716 LAEKREMMLRNEEALKEKEKLEESYFILQkeiSQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1795
Cdd:COG5022   805 LLGSRKEYRSYLACIIKLQKTIKREKKLR---ETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELA- 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1796 taedamqimEQMTKEKTETLASLEDTKQTNARLQNEL---------DTLKENNLKTvEELNKSKELL---SVENQKMEEF 1863
Cdd:COG5022   881 ---------ERQLQELKIDVKSISSLKLVNLELESEIielkkslssDLIENLEFKT-ELIARLKKLLnniDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1864 KK-----EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLR------ 1932
Cdd:COG5022   951 VKlpelnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEvaelqs 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1933 ESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlk 2011
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV--- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 2012 eNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKK 2091
Cdd:COG5022  1104 -TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRL 1182


                  .
gi 568937382 2092 K 2092
Cdd:COG5022  1183 Y 1183
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-803 3.39e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHD----------QHVLELE 406
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeaveARREELE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  407 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRL 486
Cdd:PRK02224  321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERF 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  487 ESSkpPGDVDMSLSLLQEisaLQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ-----------KEIK-ALHTAT------ 548
Cdd:PRK02224  401 GDA--PVDLGNAEDFLEE---LREERDELREREAELEATLRTARERVEEAEAlleagkcpecgQPVEgSPHVETieedre 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  549 --EKLSKENESLRSKLDHANKENSDVIALwkSKLETAIASHQQAMEELkvsfSKGIGTDSAEFAELKTQIERLRldyqHE 626
Cdd:PRK02224  476 rvEELEAELEDLEEEVEEVEERLERAEDL--VEAEDRIERLEERREDL----EELIAERRETIEEKRERAEELR----ER 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  627 IESLQSKQDSERSAHAKEMETMQAKLMKiIKEKEDSLEAVKARLDSAEDqhlveMEDTLNKLQEAEikvKELEVLQAKYT 706
Cdd:PRK02224  546 AAELEAEAEEKREAAAEAEEEAEEAREE-VAELNSKLAELKERIESLER-----IRTLLAAIADAE---DEIERLREKRE 616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  707 EQSEVIGNFTSQLSAVKEKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkelv 784
Cdd:PRK02224  617 ALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEE---- 692

                         490
                  ....*....|....*....
gi 568937382  785 LTGLQDSLNQVNQVKETLE 803
Cdd:PRK02224  693 LEELRERREALENRVEALE 711
PRK11281 PRK11281
mechanosensitive channel MscK;
1824-2048 2.09e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.91  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1824 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1896
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1897 --RTRDEVTSHQKLEEERSVLNNQLLEMKKSLpsntlresefrKDADEEKASLQKSISLTSALLTEKDAELEKLRNEvtv 1974
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDL-----------AEYNSQLVSLQTQPERAQAALYANSQRLQQIRNL--- 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382 1975 LRGENATAKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEED---ERAQESQQMIDFLNSVI 2048
Cdd:PRK11281  179 LKGGKVGGKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDyltARIQRLEHQLQLLQEAI 250
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2094-2111 1.87e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.87e-04
                           10
                   ....*....|....*...
gi 568937382  2094 RLFCDICDCFDlHDTEDC 2111
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 1804-1986 2.00e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 42.44  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1804 MEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNkskellsvenQKMEEFKKEIETLKQAAAQKSQQLSA 1883
Cdd:pfam09787   49 LEELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEEAESSR----------EQLQELEEQLATERSARREAEAELER 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1884 LQEENVKLAEELGRTRDE-VTSHQKLEEERSVLNNQLleMKKSLPSNTLRESEFRKDADEEkaSLQKSISLTSALLTEKD 1962
Cdd:pfam09787  119 LQEELRYLEEELRRSKATlQSRIKDREAEIEKLRNQL--TSKSQSSSSQSELENRLHQLTE--TLIQKQTMLEALSTEKN 194

                          170       180
                   ....*....|....*....|....*..
gi 568937382  1963 A---ELEKLRNEVTVLRGENATAKSLH 1986
Cdd:pfam09787  195 SlvlQLERMEQQIKELQGEGSNGTSIN 221
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 331-683 7.72e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   331 RTGLLTETSSRYARKISGTTALQEA---LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlardghdqhvlELEA 407
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDAsrkIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE-----------NVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   408 KMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSekSRIMELEKDLALRaqevaELRRRLE 487
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIE--ARLREIEQKLNRL-----TLEKEYL 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   488 SSKPPGDVDMSLSLLQEISALQEKLEAIHTDhqgemtslKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANK 567
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGK--------KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   568 EnsdvialwKSKLETAIASHQQAMEELKVsfskgigTDSAEFAELKtQIERLRLDYQHEIESLQSKQD--SERSAHAKEM 645
Cdd:TIGR02169  904 K--------IEELEAQIEKKRKRLSELKA-------KLEALEEELS-EIEDPKGEDEEIPEEELSLEDvqAELQRVEEEI 967

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 568937382   646 ETMQAKLMKIIKEKEDsleaVKARLDSAEDQHLVEMED 683
Cdd:TIGR02169  968 RALEPVNMLAIQEYEE----VLKRLDELKEKRAKLEEE 1001
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.66e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.66e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.21e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.21e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 5.10e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.44  E-value: 5.10e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382    213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.47e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.47e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 976-1873 1.93e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.93e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   976 QDLKAKYEKAS--SETKTKHEEILQNLqkmlADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSA 1045
Cdd:TIGR02168  155 EERRAIFEEAAgiSKYKERRKETERKL----ERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1046 KKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKR 1125
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1126 YQQEHRDRESLVAEREKLLKEINAAQEELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkk 1205
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEEL--------------AELEEKLEELKEELESLEAELEELEAELEELESR--- 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1206 ltaenlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENllQTNRDLQFEKD 1285
Cdd:TIGR02168  374 --------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELE 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1286 TLRQGQEKLSASLEAtlqvkqlLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqll 1365
Cdd:TIGR02168  444 ELEEELEELQEELER-------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----------------- 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1366 hEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLL 1439
Cdd:TIGR02168  500 -NLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPL 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1440 KEKSALELQ-NGDLLADRESSIKTIGDLRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDL 1515
Cdd:TIGR02168  579 DSIKGTEIQgNDREILKNIEGFLGVAKDLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDG 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1516 SLLLKEAQDAKKNLEKEHTsmIQAKDNlnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESET 1595
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSS--ILERRR---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEE 723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1596 SLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSK 1675
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1676 SKLELQELHSCLTKILDDLRLNHEVALTERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEIS 1748
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERA 883

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1749 QLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLE 1819
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKI 963

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568937382  1820 DTKQTNAR-----LQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQA 1873
Cdd:TIGR02168  964 EDDEEEARrrlkrLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 588-1386 6.37e-21

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 100.91  E-value: 6.37e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   588 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 664
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   665 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 744
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   745 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 824
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   825 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 897
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   898 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 963
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   964 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1026
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1027 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1083
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1084 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1162
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1163 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1242
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1243 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1322
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937382  1323 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1386
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 678-1441 5.54e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.82  E-value: 5.54e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   678 LVEMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKanSEGKLELETLRQQLEGAEKQI 757
Cdd:TIGR02168  181 LERTRENLDRLEDI---LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRL--EELREELEELQEELKEAEEEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   758 KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 837
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   838 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 917
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   918 LTKANENASFLQKSIGEVTLKAEQSQ----QQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSEtKTKH 993
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAEleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR-LDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   994 EEILQNLQ------KMLADTEDKLKAAQEANRDLMQDMEELKTQADKA--KSLTYLLT----SAKKEIEVMSEELRG--- 1058
Cdd:TIGR02168  495 ERLQENLEgfsegvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAlgGRLQAVVVenlnAAKKAIAFLKQNELGrvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1059 -----LKSEKQLYAQEANALKLEKG--SLLSKLIEVETKITLLQED-------QQKLWSVNETLHLEKER---VSEEKQV 1121
Cdd:TIGR02168  575 flpldSIKGTEIQGNDREILKNIEGflGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAKKLRPGyriVTLDGDL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1122 AEKRY--QQEHRDRESLV----AEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAE 1195
Cdd:TIGR02168  655 VRPGGviTGGSAKTNSSIlerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1196 KEHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQ 1275
Cdd:TIGR02168  735 LARLEAEVEQLEER-----------IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1276 TNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRA 1355
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1356 ITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQ 1435
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963


                   ....*.
gi 568937382  1436 DSLLKE 1441
Cdd:TIGR02168  964 EDDEEE 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 743-1531 7.16e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.89  E-value: 7.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   743 LETLRQQLEGAEKQIKNLETERNAESS----KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSE 818
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAELRELELAllvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   819 EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLT 898
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   899 KMNDELRLKERSVEELQLKLTKANENASFLQKSIgevtlKAEQSQQQAARKHEEEKKELEEKLLELEKKMEtsynqcQDL 978
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQI-----ASLNNEIERLEARLERLEDRRERLQQEIEELL------KKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   979 KAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLtsakkeiEVMSEELRG 1058
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-------ERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1059 LKSEKQLYAQEANALKLEKGsLLSKLIEVETKI-----TLLQEDQQKLWSVNETL------HLEKERVSE---------- 1117
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILG-VLSELISVDEGYeaaieAALGGRLQAVVVENLNAakkaiaFLKQNELGRvtflpldsik 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1118 --EKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL-KMHMENDSLEASKVSMQVLIEELRFCKD----------- 1183
Cdd:TIGR02168  583 gtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLgGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvit 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1184 -----KLMAMSEKaRAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMS 1258
Cdd:TIGR02168  663 ggsakTNSSILER-RREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1259 LDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQT 1338
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1339 SNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTL---LAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKIT 1415
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1416 YLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDL--------------RRKYDQEATNRRIVM 1481
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltleeaealenkIEDDEEEARRRLKRL 977

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937382  1482 QEKMKLLG--NIDALkKELQERKKENQELTSSKCDLslllkeaQDAKKNLEK 1531
Cdd:TIGR02168  978 ENKIKELGpvNLAAI-EEYEELKERYDFLTAQKEDL-------TEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 606-1276 2.11e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.11e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   606 SAEFAELKTQIERLRLdYQHEIESLQSKQDSERSAHAKEMETMQAKLMkIIKEKEDSLEAVKARLDSAEDQHLVEMEDTL 685
Cdd:TIGR02168  259 TAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   686 NKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDA----LRKANSEGKLELETLRQQLEGAEKQIKNLE 761
Cdd:TIGR02168  337 EELAELE---EKLEELKEELESLEAELEELEAELEELESRLEELEEqletLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   762 TERNAESSKANSITKELQEKELVLtgLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 841
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   842 NVLSSELEKLRENLTDMEAKFKEKDDRED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSV 911
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   912 EELQLKLTKANENAsfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE-LEKKMETSYNQCQDLKAKY-------- 982
Cdd:TIGR02168  572 RVTFLPLDSIKGTE--IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlGGVLVVDDLDNALELAKKLrpgyrivt 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   983 -----------------EKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAK-------- 1036
Cdd:TIGR02168  650 ldgdlvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELeelsrqis 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1037 SLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVS 1116
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1117 EEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELrfckdklmamsekaRAEK 1196
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL--------------ESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1197 EHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQT 1276
Cdd:TIGR02168  876 EALLNERASLEEA-----------LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 663-1245 1.39e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  663 LEAVKARLDSAEDqHLVEMEDTLNKLQ-EAEIKVK------ELEVLQAKYteqsevignftsQLSAVKEKLLDLDALRKA 735
Cdd:COG1196   181 LEATEENLERLED-ILGELERQLEPLErQAEKAERyrelkeELKELEAEL------------LLLKLRELEAELEELEAE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  736 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANS-------ITKELQEKELVLTGLQDSLNQVNQVKETLEKELQT 808
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyeLLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  809 LKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 888
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  889 MSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQ--SQQQAARKHEEEKKELEEKLLELEK 966
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELA 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  967 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQ----KMLADTEDKLKAAQEA------NRDLMQDMEELKTQADKAK 1036
Cdd:COG1196   488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLK 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1037 SLT------YLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1110
Cdd:COG1196   568 AAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1111 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckDKLMAMSE 1190
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER---LEEELEEE 724

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568937382 1191 KARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1245
Cdd:COG1196   725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 351-1153 1.51e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 1.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   351 ALQEALKEKQ-----QHIEQLLAERDLERAEVAKATSHVGEIEQELALArdghDQHVLELEAKMDQLRTMVEAADREKVE 425
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQEL----EEKLEELRLEVSELEEEIEELQKELYA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   426 LLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppGDVDMSLSLLQEI 505
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE--AELEELEAELEEL 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   506 SALQEKLEAIHTDHQGEMTSLKEHFG---AREEAFQKEIKALHTATEKLSKENESLRSKLDHANKEnsdvialwksKLET 582
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLELQIAslnNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK----------ELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   583 AIASHQQAMEELKVSFSKGIgTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERS----------------AHAKEME 646
Cdd:TIGR02168  441 ELEELEEELEELQEELERLE-EALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfsegvkallKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   647 TMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDT--------------------LNKLQEAEIKVKELEVLQA--- 703
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAakkaiaflkqnelgrvtflpLDSIKGTEIQGNDREILKNieg 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   704 ---------KYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEG----KLELETLR-------------QQLEGAEKQI 757
Cdd:TIGR02168  600 flgvakdlvKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivTLDGDLVRpggvitggsaktnSSILERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   758 KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 837
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   838 EEQFNVLSSELEKLRENLTDMEAKfkekddredqlvkaKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 917
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAE--------------IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   918 LTKANENASFLQKSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDLKAKYEKASSEtKTKHEEIL 997
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIES---------------LAAEIEELEELIEELESELEALLNE-RASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   998 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKsltylltSAKKEIEVMSEELRG-LKSEKQLYAQEANALKLE 1076
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-------LRLEGLEVRIDNLQErLSEEYSLTLEEAEALENK 962

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382  1077 KGSLLSKLievETKITLLQEDQQKLWSVNETlhlekerVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEE 1153
Cdd:TIGR02168  963 IEDDEEEA---RRRLKRLENKIKELGPVNLA-------AIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1006-1617 6.31e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 6.31e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1006 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1076
Cdd:COG1196   176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1077 KGSLLSKLIEVETKITLLQEDQQKLwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1156
Cdd:COG1196   255 LEELEAELAELEAELEELRLELEEL-------ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1157 MHMENDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQK 1236
Cdd:COG1196   328 LEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1237 ALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1316
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1317 TQLDcASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEK- 1395
Cdd:COG1196   484 EELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAa 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1396 --LSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADResSIKTIGDLRRKYDQE 1473
Cdd:COG1196   563 ieYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1474 ATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELktcccE 1553
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-----E 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937382 1554 KNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRL 1617
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 613-1318 2.10e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 76.31  E-value: 2.10e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   613 KTQIERLRLDYQHEIESLQSKQDSERSAHAKE-------METMQAKLMKIIKEKeDSLEAVKARLDSAEDQHLVEMEDTL 685
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQkfylrqsVIDLQTKLQEMQMER-DAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   686 NKLQEAE-IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDAL--RKANSEGKLELETLRQQLEGAEKQIKNLET 762
Cdd:pfam15921  152 HELEAAKcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   763 ERNAESSKANSITKELQ--------EKELVLTGLQDslnQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM----QDT 830
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEalksesqnKIELLLQQHQD---RIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQA 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   831 VNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK-DDREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDEL-- 904
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLhk 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   905 RLKERSVEELQLKLTKANENASFLqkSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDlKAKYEK 984
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQR---------------LEALLKAMKSECQG-QMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   985 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1064
Cdd:pfam15921  451 AAIQGKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1065 LYAQEANALKLEKGSLLSKLIEVET-KITLLQEDQqklwsVNETLHLEKERVSEekqvaekRYQQEHRDRESLVAEREKL 1143
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDK-----VIEILRQQIENMTQ-------LVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1144 LKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARAEKEhlegqVKKLTAENLVLVKDKDDVIQ 1222
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAVKD-----IKQERDQLLNEVKTSRNELN 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1223 KLQSAYEELVKDQKALVQEIEDLTTE-KKSAAEKQMSLDNTCLTLK---------------------AERENLLQTNRDL 1280
Cdd:pfam15921  671 SLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmqkqitAKRGQIDALQSKI 750

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 568937382  1281 QF----------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1318
Cdd:pfam15921  751 QFleeamtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1242-1873 2.75e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 2.75e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1242 IEDLTTEKksaaEKQMSldntclTLKAERENLLQtNRDLQFEKDTLRQgqEKLSASLEATLQVKQLLSTEAETLRTQLDC 1321
Cdd:COG1196   191 LEDILGEL----ERQLE------PLERQAEKAER-YRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1322 ASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSE 1401
Cdd:COG1196   258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1402 EVARLEmglnekityltSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVM 1481
Cdd:COG1196   338 ELEELE-----------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1482 QEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmllrdg 1561
Cdd:COG1196   407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL------------ 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1562 lnLQEECQKLNEEIREIQQTLILEKEARAKESETSlyennKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQK 1641
Cdd:COG1196   475 --LEAALAELLEELAEAAARLLLLLEAEADYEGFL-----EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1642 VEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKRE 1721
Cdd:COG1196   548 LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1722 MMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1801
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382 1802 QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELnkskELLSVENQKMEEFKKEIETLKQA 1873
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 467-1261 3.08e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.86  E-value: 3.08e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   467 ELEKDL------ALRAQEVAELRRRLEsskppgDVDMSLSLLqEISALQEKLEAIhtdhQGEMTSLKEhfgaREEAFQKE 540
Cdd:TIGR02168  197 ELERQLkslerqAEKAERYKELKAELR------ELELALLVL-RLEELREELEEL----QEELKEAEE----ELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   541 IKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGigtdSAEFAELKTQIERLR 620
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   621 LDY---QHEIESLQSKQDSERSAHAKEMETMQAkLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEIKVKE 697
Cdd:TIGR02168  337 EELaelEEKLEELKEELESLEAELEELEAELEE-LESRLEELEEQLETLRSKVAQLELQ----IASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   698 LEVLQAKYTEQSEVIGNfTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKE 777
Cdd:TIGR02168  412 LEDRRERLQQEIEELLK-KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   778 ---LQEKELVLTGLQDSLNQVNQVKETLEKELQTLKE--KFASTSEEAVSA--QTRMQD-TVNKLHQKEEQFNVLSSELE 849
Cdd:TIGR02168  491 ldsLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAAIEAalGGRLQAvVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   850 --------------KLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMkmsgDNSSQLTKMNDELRLkersveelq 915
Cdd:TIGR02168  571 grvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLL----GGVLVVDDLDNALEL--------- 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   916 LKLTKANENASFLQK---SIGEVTLKAEQSQQQAARKHEEEKKELEEKllelekkMETSYNQCQDLKAKYEKAssetKTK 992
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGdlvRPGGVITGGSAKTNSSILERRREIEELEEK-------IEELEEKIAELEKALAEL----RKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   993 HEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGL-------KSEKQL 1065
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAeeelaeaEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1066 YAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLK 1145
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1146 EINAAQEELlkmhmenDSLEASKVSMQVLIEELRFCKDKLMA----MSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVI 1221
Cdd:TIGR02168  867 LIEELESEL-------EALLNERASLEEALALLRSELEELSEelreLESKRSELRRELEELREKLAQLELRLEGLEVRID 939

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 568937382  1222 QKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDN 1261
Cdd:TIGR02168  940 NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1490-2075 6.35e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 74.33  E-value: 6.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1490 NIDALKKELQERKKENQELTSSKCDLslllkeaQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRdglnLQEECQ 1569
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENI-------EELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1570 KLNEEIREIQ-QTLILEKEARAKESETSLYEN--NKLHGRVVLLEEEIQRLRVCsEQLQTENFTLTQEKTNSEQKVEEII 1646
Cdd:PRK03918  235 ELKEEIEELEkELESLEGSKRKLEEKIRELEEriEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1647 KEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEV-ALTERAEVLQDN-KNLLAEKREMML 1724
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRlTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1725 rnEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLEsqsenrtLRKDKSKLTLKIRELETLH--SFTAAQTAEdamq 1802
Cdd:PRK03918  394 --EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHrkELLEEYTAE---- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1803 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE--NNLKTVEELNKSKELLSVEN-QKMEEFKKEIETLKQAAAQKSQ 1879
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1880 QLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESEFR---------KDADEEKASLQK 1949
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1950 SISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQ 2027
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 568937382 2028 AEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2075
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1047-1871 1.84e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.84e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1047 KEIEVMSEELRGLKSEK--QLYAQEANALKLEK-GSLLSKLIEVETKITLlqedqqklwsvNETLHLEKERVSEEKQVAE 1123
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKrqQLERLRREREKAERyQALLKEKREYEGYELL-----------KEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1124 KRYQQEHR-----DRESLVAEREKLLKEINA-----AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKAR 1193
Cdd:TIGR02169  249 LEEELEKLteeisELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1194 AEKEHLEGQVKKLTAENLVLVKDKDdviqKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1273
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRD----KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1274 LQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTC 1353
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1354 RAITDSECIQLLHEKESLAASERTLLAEKEELLSENR----IITEKLSKQSEEVARLEMGLNEKITYLTSEKE-VACQKV 1428
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDaVAKEAI 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1429 AKLKKQQDS----LLKEKSALELQNGDLLAdRESSIKTIGDLRRKYDQEATNRRIVMQEKMkLLGNIDALKKELQERK-- 1502
Cdd:TIGR02169  565 ELLKRRKAGratfLPLNKMRDERRDLSILS-EDGVIGFAVDLVEFDPKYEPAFKYVFGDTL-VVEDIEAARRLMGKYRmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1503 ---KENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmllrdglnlqeecqkLNEEIREIQ 1579
Cdd:TIGR02169  643 tleGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSS---------------------LQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1580 QtLILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQL 1659
Cdd:TIGR02169  702 N-RLDELSQELSDASRKIGEIEK---EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1660 AANIETLK-----SDFAALSKSKLELQELHSCLTKILDDL------RLNHEVALTERAEVLQDNKNLLAEKREMMLRNEE 1728
Cdd:TIGR02169  778 EEALNDLEarlshSRIPEIQAELSKLEEEVSRIEARLREIeqklnrLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1729 ALK-EKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME-- 1805
Cdd:TIGR02169  858 NLNgKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEie 937

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937382  1806 ---QMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEE----------LNKSKELLSVENQKMEEFKKEIETLK 1871
Cdd:TIGR02169  938 dpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEyeevlkrldeLKEKRAKLEEERKAILERIEEYEKKK 1016
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1285-2058 1.98e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.98e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1285 DTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdcaSKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQL 1364
Cdd:TIGR02169  194 DEKRQQLERLRREREKAERYQALLKEKREYEGYEL---LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1365 LHEKESLAASERTLLAEkeellsENRIITEKLSKQSEEVARLEMGLNEKitylTSEKEVACQKVAKLKKQQDSLLKEKSA 1444
Cdd:TIGR02169  271 EQLLEELNKKIKDLGEE------EQLRVKEKIGELEAEIASLERSIAEK----ERELEDAEERLAKLEAEIDKLLAEIEE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1445 LELQNGDLLADRESSIKTIGDLRRKYD-------QEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSL 1517
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELEdlraeleEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1518 LLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDG-------LNLQEECQKLNEEIREIQQTLIlEKEARA 1590
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLskyeqelYDLKEEYDRVEKELSKLQRELA-EAEAQA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1591 KESETSLYENNKLhgrVVLLEEEIQRLRVCSEQL-QTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSD 1669
Cdd:TIGR02169  500 RASEERVRGGRAV---EEVLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1670 FAALSKskleLQELHSCLTKILDDLRLNHEVALTERAE--------VLQDNK--NLLAEKREMMLRNEEALKEKEKLEES 1739
Cdd:TIGR02169  577 FLPLNK----MRDERRDLSILSEDGVIGFAVDLVEFDPkyepafkyVFGDTLvvEDIEAARRLMGKYRMVTLEGELFEKS 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1740 YFIlqkeisqlaqTNSHISANLLESQSenrtlRKDKSKLTLKIRELETLHsftaaQTAEDAMQIMEQMTKEKTETLASLE 1819
Cdd:TIGR02169  653 GAM----------TGGSRAPRGGILFS-----RSEPAELQRLRERLEGLK-----RELSSLQSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1820 DTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTR 1899
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1900 -DEVTSH-QKLEEERSVLNNQLLEMKKSLPSNTLRES----------EFRKDADEEKASLQKSISLTSALLTEKDAELEK 1967
Cdd:TIGR02169  793 iPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEylekeiqelqEQRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1968 LRNEVTVLRGENATAKS----LHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMIDF 2043
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKerdeLEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952

                          810
                   ....*....|....*
gi 568937382  2044 LNSVIVDLQRKNQDL 2058
Cdd:TIGR02169  953 LEDVQAELQRVEEEI 967
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 679-1576 2.45e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 2.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   679 VEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEvignftsQLSAVKEKLLDLDALRKanSEGKLELETLRQQLEGAEKQIK 758
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLE-------RLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   759 NLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN-QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 837
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   838 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimkmsgdnssqltkmnDELRLKERSVEELQLK 917
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK---------------------EELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   918 LTKANENASFLQKSIGEVTLKAEQSQQQAARKheeekkeleekllelekkmetsynqcqdlkakyekasSETKTKHEEIL 997
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRL-------------------------------------QEELQRLSEEL 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   998 QNLQKMLADTEDKLKAAQEANRDLmqdMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEK 1077
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDK---ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1078 GSLLSKLIEVETKITLLQEDQQKLW-SVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1156
Cdd:TIGR02169  500 RASEERVRGGRAVEEVLKASIQGVHgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLP 579

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1157 MH-MENDSLEASKVSMQVLIE---ELRFCKDK-------------LMAMSEKARAekehLEGQVKKLTAENLVLvkDKDD 1219
Cdd:TIGR02169  580 LNkMRDERRDLSILSEDGVIGfavDLVEFDPKyepafkyvfgdtlVVEDIEAARR----LMGKYRMVTLEGELF--EKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1220 VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaekqmsldntcltLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLE 1299
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1300 ATLQVKQLLSTEAETLRtqldcaskalRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLL 1379
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK----------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1380 AEKEellsenRIITEKLSKQSEEVARLEMGLNE---KITYLTSEKEVACQKVAKLKKQQDsllkeksALELQNGDLLADR 1456
Cdd:TIGR02169  790 HSRI------PEIQAELSKLEEEVSRIEARLREieqKLNRLTLEKEYLEKEIQELQEQRI-------DLKEQIKSIEKEI 856

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1457 ESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM 1536
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 568937382  1537 IQAKDNLNAElktccCEKNMLLRDglnLQEECQKLNEEIR 1576
Cdd:TIGR02169  937 EDPKGEDEEI-----PEEELSLED---VQAELQRVEEEIR 968
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 2.49e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 72.41  E-value: 2.49e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937382  211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 733-1407 2.80e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 2.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  733 RKANSEGKLE--------LETLRQQLEgaeKQIKNLETERN-AEssKANSITKELQEKELVLTGLQDslnqvnqvkETLE 803
Cdd:COG1196   173 RKEEAERKLEateenlerLEDILGELE---RQLEPLERQAEkAE--RYRELKEELKELEAELLLLKL---------RELE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  804 KELQTLKEKFASTSEEAVSAQTRMQDtvnklhqkeeqfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDI 883
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAE--------------LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  884 AEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 963
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  964 LEKKME--TSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1041
Cdd:COG1196   385 AEELLEalRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1042 LTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVetKITLLQEDQQKLW-SVNETLHLEKERVSEEKQ 1120
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAgAVAVLIGVEAAYEAALEA 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1121 VAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckdklmamsekaraekehle 1200
Cdd:COG1196   543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV--------------------- 601

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1201 gqvkkltaenlvlvkdkdDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDL 1280
Cdd:COG1196   602 ------------------DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1281 QFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEiktcraitdse 1360
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA----------- 732

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 568937382 1361 ciqllhEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLE 1407
Cdd:COG1196   733 ------EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1313-2042 2.84e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.40  E-value: 2.84e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1313 ETLRTQLDCASKALR-KAELDMRQLQTSNSSLTKLLEEIKTCRAITDseciqllhEKESLAASERTLLAEKEELLSENRI 1391
Cdd:TIGR02168  203 KSLERQAEKAERYKElKAELRELELALLVLRLEELREELEELQEELK--------EAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1392 ITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYD 1471
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1472 ---QEATNRRIVMQEkmkLLGNIDALKKELQERKKE----NQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNL- 1543
Cdd:TIGR02168  355 sleAELEELEAELEE---LESRLEELEEQLETLRSKvaqlELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLe 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1544 NAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQ 1623
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1624 LQTEN-----FTLTQEKTNSEQKVEEIIkEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNH 1698
Cdd:TIGR02168  512 LKNQSglsgiLGVLSELISVDEGYEAAI-EAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1699 EVALTERAEVLQDNKNLLAEKREMM---------------LRNEEALKEKEKLEESYFILQKEI----SQLAQTNSHISA 1759
Cdd:TIGR02168  591 REILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddLDNALELAKKLRPGYRIVTLDGDLvrpgGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1760 NLLESQSENRTLRKDKSKLTLKIRELET-----LHSFTAAQTA-EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1833
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKalaelRKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1834 TLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVtshQKLEEERS 1913
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA---ANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1914 VLNNQLLEMKKSLPsntlRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGEnatakslhsvVQTLE 1993
Cdd:TIGR02168  828 SLERRIAATERRLE----DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA----------LALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 568937382  1994 SDKVKLELKVKNLELQLKENKRQLSSSsgnTDAQAEEDERAQESQQMID 2042
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEEL---REKLAQLELRLEGLEVRID 939
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-1001 3.53e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 72.07  E-value: 3.53e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTmveaadrekv 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRS---------- 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   425 ellnQLEEEKRKVEDlqfrveeesitkgdlevatvseksRIMELEKDLALRAQEVAELR-RRLESSKPPGDVDmslsllq 503
Cdd:pfam15921  332 ----ELREAKRMYED------------------------KIEELEKQLVLANSELTEARtERDQFSQESGNLD------- 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   504 eiSALQEKLEAIHTdHQGEMTSLKEhfgareeafqkEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKskletA 583
Cdd:pfam15921  377 --DQLQKLLADLHK-REKELSLEKE-----------QNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLK-----A 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   584 IASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhakemETMQAKLMKIIKEKEDSL 663
Cdd:pfam15921  438 MKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESS-----ERTVSDLTASLQEKERAI 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   664 EAVKAR---------LDSAEDQHLVEMEDTLN---------KLQEAEiKVKELEVLQAKYTEQSEVIGNFTSQLSAVkek 725
Cdd:pfam15921  513 EATNAEitklrsrvdLKLQELQHLKNEGDHLRnvqtecealKLQMAE-KDKVIEILRQQIENMTQLVGQHGRTAGAM--- 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   726 LLDLDALRKANSEGKLELETLR-------QQLEGAEKQIKNLETER----NAESSKANSITKELQEKELVLTGLQDSLNQ 794
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKvklvNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   795 VNQVKEtlekELQTLKEKFASTSEEavsaqtrMQDTVNKLHQkeeQFNVLSSELEKLRENLTDMEAKfkekddredqlvk 874
Cdd:pfam15921  669 LNSLSE----DYEVLKRNFRNKSEE-------METTTNKLKM---QLKSAQSELEQTRNTLKSMEGS------------- 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   875 akeklendIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQ----KSIGEVTLKAEQSQQQAA--- 947
Cdd:pfam15921  722 --------DGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKeeknKLSQELSTVATEKNKMAGele 793

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382   948 --RKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQ 1001
Cdd:pfam15921  794 vlRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 344-1160 4.35e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 4.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   344 RKISGTTALQEALKEKQQH---IEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAK----MDQLRTMV 416
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALerqKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeQLRVKEKI 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   417 EAADREKVELLNQLEEEKRKVEDLQFRVEEesitkgdLEVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvd 496
Cdd:TIGR02169  297 GELEAEIASLERSIAEKERELEDAEERLAK-------LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK------ 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   497 mslsllQEISALQEKLEAIHTDHQgemTSLKEHFGARE--EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDV-- 572
Cdd:TIGR02169  364 ------EELEDLRAELEEVDKEFA---ETRDELKDYREklEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIea 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   573 -IALWKSKLETAIASHQQAMEELKvSFSKGIGTDSAEFAELKTQIERLrldyQHEIESLQSKQDsERSAHAKEMETMQAK 651
Cdd:TIGR02169  435 kINELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQELYDLKEEYDRV----EKELSKLQRELA-EAEAQARASEERVRG 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   652 LMKIIKEKEDSLEAVK---ARLDSAEDQHLVEMEDTL-NKLQEAeikVKELEVLQAKYTE--QSEVIGNFTS-QLSAVKE 724
Cdd:TIGR02169  509 GRAVEEVLKASIQGVHgtvAQLGSVGERYATAIEVAAgNRLNNV---VVEDDAVAKEAIEllKRRKAGRATFlPLNKMRD 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   725 KLLDLDALRKANSEG-KLELETLRQQLEGAEKQI-------KNLETERNAESS-KANSITKELQEKELVLTG-------- 787
Cdd:TIGR02169  586 ERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARRLMGKyRMVTLEGELFEKSGAMTGgsraprgg 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   788 ------LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAK 861
Cdd:TIGR02169  666 ilfsrsEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   862 FKEKDdredqlvkakEKLENDIAEimkmsgdnssqLTKMNDELRLKERSVEELQLKLT--KANENASFLQKSIGEVT-LK 938
Cdd:TIGR02169  746 LSSLE----------QEIENVKSE-----------LKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSkLE 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   939 AEQSQQQAARKH-EEEKKELEEKLLELEKKMETSYNQCQDLKAKyekassetKTKHEEILQNLQKMLADTEDKLKAAQEA 1017
Cdd:TIGR02169  805 EEVSRIEARLREiEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ--------IKSIEKEIENLNGKKEELEEELEELEAA 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1018 NRDLMQDMEELKTQADKAKsltylltsakKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQED 1097
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELE----------AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI 946

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382  1098 QQKLWSVnETLHLEKERVSEEKQV--------------AEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHME 1160
Cdd:TIGR02169  947 PEEELSL-EDVQAELQRVEEEIRAlepvnmlaiqeyeeVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 577-1148 8.92e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 8.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  577 KSKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKlmKII 656
Cdd:COG1196   241 LEELEAELEELEAELEELE-----------AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI--ARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  657 KEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELE-VLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKA 735
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEeELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  736 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFAS 815
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  816 TSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDRE-----DQLVKAKEKLENDIAEIMKMS 890
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavAVLIGVEAAYEAALEAALAAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  891 G-----DNSSQLTKMNDEL-RLKERSVEELQL---KLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKL 961
Cdd:COG1196   548 LqnivvEDDEVAAAAIEYLkAAKAGRATFLPLdkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  962 LELEKKMETSYN------------QCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELK 1029
Cdd:COG1196   628 VAARLEAALRRAvtlagrlrevtlEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1030 TQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNetlh 1109
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVN---- 783

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 568937382 1110 lekERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEIN 1148
Cdd:COG1196   784 ---LLAIEEYEELEERYDFLSEQREDLEEARETLEEAIE 819
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 879-1788 1.72e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.10  E-value: 1.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   879 LENDIAEIMKMSG--------------DNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSigevTLKAEQSQQ 944
Cdd:TIGR02169  140 LQGDVTDFISMSPverrkiideiagvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERYQA 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   945 QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKakyekassETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQD 1024
Cdd:TIGR02169  216 LLKEKREYEGYELLKEKEALERQKEAIERQLASLE--------EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1025 mEELKTQADKAkSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSV 1104
Cdd:TIGR02169  288 -EQLRVKEKIG-ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1105 NETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASkvsmqvlIEELRFCKDK 1184
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA-------IAGIEAKINE 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1185 LMAMSEKARAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCL 1264
Cdd:TIGR02169  439 LEEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1265 TLKAERENLLQTNRDL-QFEKDTLRQGQEKLSASLEATLQVKQLLSTEAetlrTQLDCASKALRKAELDMRQLQTSNSSL 1343
Cdd:TIGR02169  515 VLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDAVAKEA----IELLKRRKAGRATFLPLNKMRDERRDL 590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1344 TKLLEEIKTCRAITDSECIQlLHEKESLAASERTLLAEKEE----LLSENRIIT---EKLSKQSEEV--ARLEMGLNEKI 1414
Cdd:TIGR02169  591 SILSEDGVIGFAVDLVEFDP-KYEPAFKYVFGDTLVVEDIEaarrLMGKYRMVTlegELFEKSGAMTggSRAPRGGILFS 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1415 TYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDAL 1494
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1495 KKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKehtsmiqakdnlnaelktccceknMLLRDGL-NLQEECQKLNE 1573
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA------------------------RLSHSRIpEIQAELSKLEE 805

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1574 EIREIqqtlilekEARAKESETSLyenNKLHGRVVLLEEEIQrlrvcseQLQTENFTLTQEKTNSEQKVEEIIKEKELLS 1653
Cdd:TIGR02169  806 EVSRI--------EARLREIEQKL---NRLTLEKEYLEKEIQ-------ELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1654 AETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVA------LTERAEVLQDNKNLLAEKREMMLRNE 1727
Cdd:TIGR02169  868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKrkrlseLKAKLEALEEELSEIEDPKGEDEEIP 947

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382  1728 EALKEKEKLEESYFILQKEISQLAQTN-------SHISANLLESQSENRTLRKDKSKLTLKIRELETL 1788
Cdd:TIGR02169  948 EEELSLEDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 352-1152 1.72e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.10  E-value: 1.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   352 LQEALKEKQQHIEQLLAERD--------LERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRTMVEAADREK 423
Cdd:TIGR02169  189 LDLIIDEKRQQLERLRREREkaeryqalLKEKREYEGYELLKEKEALERQKEAIERQ-LASLEEELEKLTEEISELEKRL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   424 VELLNQLEEEKRKVEDLqfrveeesitkGDLEVATVSEKSRIMELEKDLALRAQEVAELR-RRLESSKPPGDVDMSlSLL 502
Cdd:TIGR02169  268 EEIEQLLEELNKKIKDL-----------GEEEQLRVKEKIGELEAEIASLERSIAEKERElEDAEERLAKLEAEID-KLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   503 QEISALQEKLEaihtDHQGEMTSLKEHFGARE---EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSK 579
Cdd:TIGR02169  336 AEIEELEREIE----EERKRRDKLTEEYAELKeelEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   580 LETAIASHQQaMEELKVSFsKGIGTDSAEF-AELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETmQAKLMKIIKE 658
Cdd:TIGR02169  412 QEELQRLSEE-LADLNAAI-AGIEAKINELeEEKEDKALEIKKQEW-KLEQLAADLSKYEQELYDLKEE-YDRVEKELSK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   659 KEDSLEAVKARLDSAEDQHL--VEMEDTLNK-------LQEAEIKVKE-----LEV-----LQAKYTEQSEV-------- 711
Cdd:TIGR02169  488 LQRELAEAEAQARASEERVRggRAVEEVLKAsiqgvhgTVAQLGSVGEryataIEVaagnrLNNVVVEDDAVakeaiell 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   712 ----IGNFTS-QLSAVKEKLLDLDALRKANSEG-KLELETLRQQLEGAEKQI-------KNLETERN-AESSKANSITKE 777
Cdd:TIGR02169  568 krrkAGRATFlPLNKMRDERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARRlMGKYRMVTLEGE 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   778 LQEKELVLTG--------------LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNV 843
Cdd:TIGR02169  648 LFEKSGAMTGgsraprggilfsrsEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   844 LSSELEKLRENLTDMEAKFKEKDdredqlvkakEKLENDIAEimkmsgdnssqLTKMNDELRLKERSVEELQLKLT--KA 921
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLE----------QEIENVKSE-----------LKELEARIEELEEDLHKLEEALNdlEA 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   922 NENASFLQKSIGEVT-LKAEQSQQQAARKH-EEEKKELEEKLLELEKKMETSYNQCQDLKAKyekassetKTKHEEILQN 999
Cdd:TIGR02169  787 RLSHSRIPEIQAELSkLEEEVSRIEARLREiEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ--------IKSIEKEIEN 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1000 LQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKaksltylltsAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGS 1079
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDE----------LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1080 LLSKLIEVETKITLLQEDQQKLWSVnETLHLEKERVSEEKQ-------VAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1152
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRalepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 406-1118 2.66e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.38  E-value: 2.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   406 EAKMDQLRTMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESITKGDLE------VATVSEKSRIMELEKDLAL----- 474
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESNELHEKQKfylrqsVIDLQTKLQEMQMERDAMAdirrr 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   475 RAQEVAELRRRLESSKPPGDVDMSLS--LLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEI----------- 541
Cdd:pfam15921  136 ESQSQEDLRNQLQNTVHELEAAKCLKedMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIyehdsmstmhf 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   542 KALHTATEKLSKENESLRSKLdhankenSDVIALWKSKLETAIASHQQAMEELkvsfskgigtdsaeFAELKTQIERLRL 621
Cdd:pfam15921  216 RSLGSAISKILRELDTEISYL-------KGRIFPVEDQLEALKSESQNKIELL--------------LQQHQDRIEQLIS 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   622 DYQHEIESLQSKQDSERS---AHAKEMETMQ-------AKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEA 691
Cdd:pfam15921  275 EHEVEITGLTEKASSARSqanSIQSQLEIIQeqarnqnSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLA 354

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   692 EIKVKELEVLQAKYTEQSeviGNFTSQLSAV------KEKLLDLDA-----LRKANSEGKLELETLRQQLEGAEKQIKNL 760
Cdd:pfam15921  355 NSELTEARTERDQFSQES---GNLDDQLQKLladlhkREKELSLEKeqnkrLWDRDTGNSITIDHLRRELDDRNMEVQRL 431

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   761 ETERNAESSKANSitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLK---EKFASTSEEAVSAQTRMQDTVNKLHQK 837
Cdd:pfam15921  432 EALLKAMKSECQG---QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRkvvEELTAKKMTLESSERTVSDLTASLQEK 508

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   838 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLE---------NDIAEIMKMSGDNSSQLT---------- 898
Cdd:pfam15921  509 ERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmaekDKVIEILRQQIENMTQLVgqhgrtagam 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   899 ---KMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQ-QAARKHEEEKKELEEKLLELEKKMETSYNQ 974
Cdd:pfam15921  589 qveKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   975 CQDLKAKYEKASSETKTKHEEILQNLQKMladtEDKLKAAQ---EANRDLMQDMEELKTQADK-AKSLTYLLTSAKKEIE 1050
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTNKL----KMQLKSAQselEQTRNTLKSMEGSDGHAMKvAMGMQKQITAKRGQID 744

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382  1051 VMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETkitllqeDQQKLWSVNETLHLEKERVSEE 1118
Cdd:pfam15921  745 ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAT-------EKNKMAGELEVLRSQERRLKEK 805
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-915 3.73e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 3.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  351 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELALARdghdQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:COG1196   217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELEELE----AELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  431 EEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPpgDVDMSLSLLQEISALQE 510
Cdd:COG1196   291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE--ELEEAEAELAEAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  511 KLEAIHTDHQGEMTSLKEhfgaREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQA 590
Cdd:COG1196   369 EAEAELAEAEEELEELAE----ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  591 MEELKvsfskgigtDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEmETMQAKLMKIIKEKEDSLEAVKARL 670
Cdd:COG1196   445 EEAAE---------EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA-AARLLLLLEAEADYEGFLEGVKAAL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  671 DSAEDQHL---VEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVignftsqlsavkekLLDLDALRKANSEGKLELETLR 747
Cdd:COG1196   515 LLAGLRGLagaVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV--------------AAAAIEYLKAAKAGRATFLPLD 580

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  748 QQlegAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM 827
Cdd:COG1196   581 KI---RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGS 657

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  828 QDTVNKLHQKEEQfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLK 907
Cdd:COG1196   658 AGGSLTGGSRREL---LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734


                  ....*...
gi 568937382  908 ERSVEELQ 915
Cdd:COG1196   735 EELLEELL 742
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 837-1733 6.22e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 6.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   837 KEEQFNVLSSELEklrenltdmEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQL 916
Cdd:TIGR02169  209 KAERYQALLKEKR---------EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   917 KLTKANENASF-LQKSIGEVTLKAEQSQQQAARKheeekkeleekllelEKKMETSYNQCQDLKAKYEKASSEtKTKHEE 995
Cdd:TIGR02169  280 KIKDLGEEEQLrVKEKIGELEAEIASLERSIAEK---------------ERELEDAEERLAKLEAEIDKLLAE-IEELER 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   996 ILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLtylLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKL 1075
Cdd:TIGR02169  344 EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE---LKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1076 EKGSLLSKLIEVETKITLLQEdqqklwsvnetlhlEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL 1155
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEE--------------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1156 KMHMENDSLEASKvsmQVLIEELRFCKdklmAMSEKARAEKEHLEGQVKKL----------------TAENLVLVKDKDD 1219
Cdd:TIGR02169  487 KLQRELAEAEAQA---RASEERVRGGR----AVEEVLKASIQGVHGTVAQLgsvgeryataievaagNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1220 VIQKLqsayeELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAereNLLQTnrDLQFEK-------DTLrqgqe 1292
Cdd:TIGR02169  560 AKEAI-----ELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAV---DLVEF--DPKYEPafkyvfgDTL----- 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1293 kLSASLEAT---LQVKQLLSTEAETLRTQ--LDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHE 1367
Cdd:TIGR02169  625 -VVEDIEAArrlMGKYRMVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1368 KESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALEL 1447
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE----EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1448 QNGDLLAD-RESSIKTIGDLRRKydQEATNRRIVmqekmkllGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAK 1526
Cdd:TIGR02169  780 ALNDLEARlSHSRIPEIQAELSK--LEEEVSRIE--------ARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1527 KNLEKEHTSMIQAKDNLNAELKtcccEKNMLLRDglnLQEECQKLNEEIREIQQTLileKEARAKESEtslyennklhgr 1606
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELE----ELEAALRD---LESRLGDLKKERDELEAQL---RELERKIEE------------ 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1607 vvlLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKE-KELLSAEtaQLAANIETLKSDFAALSKSKLELQELHS 1685
Cdd:TIGR02169  908 ---LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpEEELSLE--DVQAELQRVEEEIRALEPVNMLAIQEYE 982

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 568937382  1686 CLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEK 1733
Cdd:TIGR02169  983 EVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEAINEN 1030
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 7.50e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.40  E-value: 7.50e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 335-886 8.25e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 8.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGH---DQHVLELEAKMDQ 411
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRrelEERLEELEEELAE 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  412 LRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLEsskp 491
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE---- 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  492 pgdvdmslSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSD 571
Cdd:COG1196   404 --------ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  572 VIALWKSKLETAIAS----HQQAMEELKVSFSKGIGtdsaefaeLKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMET 647
Cdd:COG1196   476 EAALAELLEELAEAAarllLLLEAEADYEGFLEGVK--------AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  648 MQAKLMKIIKEKEDSLEAVKARLDS-AEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKL 726
Cdd:COG1196   548 LQNIVVEDDEVAAAAIEYLKAAKAGrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  727 LDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKEL 806
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  807 QTLKEKFASTSEEAVSAQtrmqdtvnKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEI 886
Cdd:COG1196   708 ELAEAEEERLEEELEEEA--------LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 344-886 1.25e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  344 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREK 423
Cdd:COG1196   295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  424 VELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppGDVDMSLSLLQ 503
Cdd:COG1196   375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--EALEEAAEEEA 452

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  504 EISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETA 583
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  584 IASHQQAMEELKVSFSKGIGTDSAEfaELKTQIERLRLDYQHEIESLQSkqDSERSAHAKEMETMQAKLMKIIKEKEDSL 663
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDE--VAAAAIEYLKAAKAGRATFLPL--DKIRARAALAAALARGAIGAAVDLVASDL 608

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  664 EAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLEL 743
Cdd:COG1196   609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  744 ETLRQQLEGAEKQIKNLETERNAESSkansitKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSA 823
Cdd:COG1196   689 AEEELELEEALLAEEEEERELAEAEE------ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382  824 QTrMQDTVNKLHQKEEQF---NVLS-SELEKLRENLTDMEAKfkekddREDqLVKAKEKLENDIAEI 886
Cdd:COG1196   763 EE-LERELERLEREIEALgpvNLLAiEEYEELEERYDFLSEQ------RED-LEEARETLEEAIEEI 821
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 742-1255 1.26e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.97  E-value: 1.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   742 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQdslnQVNQVKETLEKELQTLKEKFASTSEEAV 821
Cdd:TIGR04523  160 KYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLK----KKIQKNKSLESQISELKKQNNQLKDNIE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   822 SAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQltKMN 901
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK--ELK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   902 DELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAE--------QSQQQAARKHEEEKKELEEKLLELEKKMETSYN 973
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQ--LKKEltnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLES 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   974 QCQDLKAKYEKASSETKTKHEEI--LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKA-KSLTYLLTSAKKEIE 1050
Cdd:TIGR04523  392 QINDLESKIQNQEKLNQQKDEQIkkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiKNLDNTRESLETQLK 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1051 VMSEELRGLKS-------EKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSvnETLHLEKERVSEEKQVAE 1123
Cdd:TIGR04523  472 VLSRSINKIKQnleqkqkELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES--EKKEKESKISDLEDELNK 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1124 KRYqqehrdreslVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQV 1203
Cdd:TIGR04523  550 DDF----------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937382  1204 KKLTAENlvlvKDKDDVIQKLQSAYEELVKDQKaLVQEIEDLTTEKKSAAEK 1255
Cdd:TIGR04523  620 EKAKKEN----EKLSSIIKNIKSKKNKLKQEVK-QIKETIKEIRNKWPEIIK 666
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
646-1273 1.99e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.24  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  646 ETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemedtlNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEK 725
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIE--------ELIKEKE---KELEEVLREINEISSELPELREELEKLEKE 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  726 LLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLET---ERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETL 802
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEErieELKKEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  803 EKELQTLKEKFASTSEEAVSAQTRMQDTVNKlhqkeeqfnvlSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENd 882
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEERIKELEEK-----------EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE- 373

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  883 IAEIMKMSGDNSsqLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtlkaeqsqqqaarkheeekkeleekll 962
Cdd:PRK03918  374 LERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE---------------------------- 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  963 elekkMETSYNQCQDLKAKYEKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1041
Cdd:PRK03918  424 -----LKKAIEELKKAKGKCPVCGRELTEEHRkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1042 LTSAkKEIEVMSEELRGLKSEKqlyaQEANALKLEKgsLLSKLIEVETKITLLQEDQQKLwsvnETLHLEKERVSEEKQV 1121
Cdd:PRK03918  499 KELA-EQLKELEEKLKKYNLEE----LEKKAEEYEK--LKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDE 567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1122 AEKRYQQEHRDRESLVAEReklLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLmamsEKARAEKEHLEG 1201
Cdd:PRK03918  568 LEEELAELLKELEELGFES---VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL----DKAFEELAETEK 640

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382 1202 QVKKLTAENLVLVKDKDDviqklqSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1273
Cdd:PRK03918  641 RLEELRKELEELEKKYSE------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 412-1261 2.55e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.15  E-value: 2.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   412 LRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVsEKSRIMELEKDLALRAQEVAELRRRLESSKp 491
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE-EYLLYLDYLKLNEERIDLLQELLRDEQEEI- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   492 pgdvdmsLSLLQEISALQEKLEAIHTDHQGEMtslkehfgaREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSD 571
Cdd:pfam02463  254 -------ESSKQEIEKEEEKLAQVLKENKEEE---------KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLK 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   572 VIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAK 651
Cdd:pfam02463  318 ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   652 LMKIIKEKEDSLEAVKAR--------LDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVK 723
Cdd:pfam02463  398 ELKSEEEKEAQLLLELARqledllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKET 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   724 EKLLDLDALRKANSEGKLELETLRQQ-LEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETL 802
Cdd:pfam02463  478 QLVKLQEQLELLLSRQKLEERSQKESkARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   803 EKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEND 882
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   883 IAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLL 962
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL-QEKAESELAKEEILRRQLEIKKKEQREKEELKKLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   963 ELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLL 1042
Cdd:pfam02463  717 LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1043 TSAKKEIEVMSEElrgLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVA 1122
Cdd:pfam02463  797 KAQEEELRALEEE---LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1123 EKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQ 1202
Cdd:pfam02463  874 LKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEEN 953

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937382  1203 VKKLTAENLVLVKDKDD----VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDN 1261
Cdd:pfam02463  954 NKEEEEERNKRLLLAKEelgkVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1543-2070 3.04e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 3.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1543 LNAELKTCccEKNMLLRDGLNLQEECQKLNEEIREIQQTLI-LEKEARAKESEtslyennklhgrVVLLEEEIQRLRVCS 1621
Cdd:COG1196   218 LKEELKEL--EAELLLLKLRELEAELEELEAELEELEAELEeLEAELAELEAE------------LEELRLELEELELEL 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1622 EQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVA 1701
Cdd:COG1196   284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1702 LTERAEVLQDNKNLLAEKREmmLRNEEALKEKEKLEEsyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLK 1781
Cdd:COG1196   364 EEALLEAEAELAEAEEELEE--LAEELLEALRAAAEL-----AAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1782 IRELEtlhsftaaQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlKTVEELNKSKELLSVENQKME 1861
Cdd:COG1196   437 EEEEE--------EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE---ELAEAAARLLLLLEAEADYEG 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1862 EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKS-------LPSNTLRES 1934
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIRAR 585

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1935 EFRKDADEEKASLQKSISLTSALltekDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENK 2014
Cdd:COG1196   586 AALAAALARGAIGAAVDLVASDL----READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS 661

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382 2015 RQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAAL 2070
Cdd:COG1196   662 LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1341-2017 5.08e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 64.74  E-value: 5.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1341 SSLTKLLEEIKTCRAITDSEciqlLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGL---NEKITYL 1417
Cdd:pfam05483   81 SKLYKEAEKIKKWKVSIEAE----LKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikeNNATRHL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1418 TSEKEVACQKVAKLKKQQDSLLKEKSALELqngDLLADRESSIKTIGDLRrkydQEATNRRIVMQEKMKL-LGNIDALKK 1496
Cdd:pfam05483  157 CNLLKETCARSAEKTKKYEYEREETRQVYM---DLNNNIEKMILAFEELR----VQAENARLEMHFKLKEdHEKIQHLEE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1497 ELQER--KKENQ---------ELTSSKCDLSLLLKEAQDAKKNLEKEHT-------SMIQAKDNLNAELKTCCCEKNMLL 1558
Cdd:pfam05483  230 EYKKEinDKEKQvsllliqitEKENKMKDLTFLLEESRDKANQLEEKTKlqdenlkELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1559 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEE----EIQRLRVCSEQLQTENFTLtQE 1634
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtEQQRLEKNEDQLKIITMEL-QK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1635 KTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILD-------DLRLNHEVALTERAE 1707
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQarekeihDLEIQLTAIKTSEEH 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1708 VLQDNKNLLAEKREMMLRNEEALKEKEKLeesyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELET 1787
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKL-------LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1788 lhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEI 1867
Cdd:pfam05483  542 ----KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEN 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1868 ETLKQAAAQKSQQLSALQEENVKLAEELGRTRdevtshQKLEEERSVLNNQlLEMKKSLPSNTLRESEFRKDADEEKASL 1947
Cdd:pfam05483  618 KALKKKGSAENKQLNAYEIKVNKLELELASAK------QKFEEIIDNYQKE-IEDKKISEEKLLEEVEKAKAIADEAVKL 690

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382  1948 QKSISL-TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2017
Cdd:pfam05483  691 QKEIDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
655-1195 7.64e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.29  E-value: 7.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  655 IIKEKEDSLEAVKARLDSAEDQHLVEmedtlnKLQEAEIKVKELEvlqakyteqsEVIGNFTSQLSAVKEKLLDLDALRK 734
Cdd:PRK02224  181 VLSDQRGSLDQLKAQIEEKEEKDLHE------RLNGLESELAELD----------EEIERYEEQREQARETRDEADEVLE 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  735 ANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFA 814
Cdd:PRK02224  245 EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  815 STSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK----DDREDQLvkakEKLENDIAEIMKMS 890
Cdd:PRK02224  325 ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreavEDRREEI----EELEEEIEELRERF 400

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  891 GDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSI--GEVTLKA----EQSQQQAARKHEEEKKELEEKLLEL 964
Cdd:PRK02224  401 GDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVeeAEALLEAgkcpECGQPVEGSPHVETIEEDRERVEEL 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  965 EKKMETSYNQCQDLKAKYEKASSETKT-----KHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLT 1039
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEDLVEAedrieRLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1040 yllTSAKKEIEVMSEELRGLKSEKQLYAQEANAL-KLEkgSLLSKLIEVETKITLLQEDQQKLWSVN----ETLHLEKER 1114
Cdd:PRK02224  561 ---AEAEEEAEEAREEVAELNSKLAELKERIESLeRIR--TLLAAIADAEDEIERLREKREALAELNderrERLAEKRER 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1115 VSE---------------EKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQ---EELLKMHMENDSLEASKVSMQVLIE 1176
Cdd:PRK02224  636 KREleaefdearieeareDKERAEEYLEQVEEKLDELREERDDLQAEIGAVEnelEELEELRERREALENRVEALEALYD 715

                         570
                  ....*....|....*....
gi 568937382 1177 ELrfckDKLMAMSEKARAE 1195
Cdd:PRK02224  716 EA----EELESMYGDLRAE 730
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 775-1839 1.71e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 63.27  E-value: 1.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   775 TKELQEK-ELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLH-------QKEEQFNVLSS 846
Cdd:pfam01576   17 VKERQQKaESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHelesrleEEEERSQQLQN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   847 ELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 926
Cdd:pfam01576   97 EKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAK 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   927 FLQK---------SIGEVTLKAEQSQQQAARKHEEEKKELEEKLLElekkmetsynQCQDLKAKYEKASSETKTKHEEiL 997
Cdd:pfam01576  177 SLSKlknkheamiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQE----------QIAELQAQIAELRAQLAKKEEE-L 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   998 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQ------LYAQEAN 1071
Cdd:pfam01576  246 QAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR---NKAEKQRRDLGEELEALKTELEdtldttAAQQELR 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1072 ALKLEKGSLLSKLIEVETKI--TLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKryqqehrDRESLVAEREKLLKEINA 1149
Cdd:pfam01576  323 SKREQEVTELKKALEEETRSheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK-------AKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1150 AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYE 1229
Cdd:pfam01576  396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1230 ELVKDQKALVQeiedLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLS 1309
Cdd:pfam01576  476 LLQEETRQKLN----LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1310 TEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTklleeiktcraitdsecIQLLHEKESLAASERTlLAEKEELLSEN 1389
Cdd:pfam01576  552 RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL-----------------VDLDHQRQLVSNLEKK-QKKFDQMLAEE 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1390 RIITeklSKQSEEVARLEMGLNEKITyltsekevacqKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDL--- 1466
Cdd:pfam01576  614 KAIS---ARYAEERDRAEAEAREKET-----------RALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgkn 679

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1467 -------RRKYDQEATNRRIVMQE-----------KMKLLGNIDALK----KELQERKKENQEltsskcDLSLLLKEAQD 1524
Cdd:pfam01576  680 vhelersKRALEQQVEEMKTQLEEledelqatedaKLRLEVNMQALKaqfeRDLQARDEQGEE------KRRQLVKQVRE 753

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1525 AKKNLEKEHTSMIQA---KDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEAR------AKESET 1595
Cdd:pfam01576  754 LEAELEDERKQRAQAvaaKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRdeilaqSKESEK 833

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1596 SLyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSK 1675
Cdd:pfam01576  834 KL---KNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLND 910

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1676 SKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMmlrnEEALKEKEKLEESYFilqkeISQLAQTNS 1755
Cdd:pfam01576  911 RLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEM----EGTVKSKFKSSIAAL-----EAKIAQLEE 981

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1756 HISANLLESQSENRTLRKDKSKL--TLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1833
Cdd:pfam01576  982 QLEQESRERQAANKLVRRTEKKLkeVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELD 1061


                   ....*.
gi 568937382  1834 TLKENN 1839
Cdd:pfam01576 1062 DATESN 1067
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1113-1752 2.93e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 2.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1113 ERVSEEKQVAEK----RYQQEHRDRESLVAEREKLLKEINAAQEELlkmhmendsleaskvsmqvlieelrfckDKLMAM 1188
Cdd:COG1196   203 EPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAEL----------------------------EELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1189 SEKARAEKEHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKA 1268
Cdd:COG1196   255 LEELEAELAELEAELEELRLE-----------LEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1269 ERENLLQTNRDLQFEKDTLRQGQEKLSASLEAT-LQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLL 1347
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAeAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1348 EEIKTCRAITDsECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQK 1427
Cdd:COG1196   404 ELEEAEEALLE-RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1428 VAKLKKQQDSLLKEKSALELQNGDLLADREssIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERkkenqe 1507
Cdd:COG1196   483 LEELAEAAARLLLLLEAEADYEGFLEGVKA--ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE------ 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1508 ltsskcDLSLLLKEAQDAKKNLEKEHTSMIQAKdnlnaelktccceknMLLRDGLNLQEECQKLNEEIREIQQTLILEKE 1587
Cdd:COG1196   555 ------DDEVAAAAIEYLKAAKAGRATFLPLDK---------------IRARAALAAALARGAIGAAVDLVASDLREADA 613

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1588 ARAKESETSL---YENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIE 1664
Cdd:COG1196   614 RYYVLGDTLLgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1665 TLKSDFAALSKSKLELQELhscltkiLDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQ 1744
Cdd:COG1196   694 ELEEALLAEEEEERELAEA-------EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                  ....*...
gi 568937382 1745 KEISQLAQ 1752
Cdd:COG1196   767 RELERLER 774
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1221-1811 3.09e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1221 IQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEkqmsLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEA 1300
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1301 TLQVKQLLsteaETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKtcraitdsECIQLLHEKESLAASERTLLA 1380
Cdd:PRK03918  233 LEELKEEI----EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--------EKVKELKELKEKAEEYIKLSE 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1381 EKEELLSENRIITEKLSKQSEEVArlemGLNEKITYLTSEKEvacqKVAKLKKQQDSLLKEKSALE-----LQNGDLLAD 1455
Cdd:PRK03918  301 FYEEYLDELREIEKRLSRLEEEIN----GIEERIKELEEKEE----RLEELKKKLKELEKRLEELEerhelYEEAKAKKE 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1456 RESSIK------TIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSK-----CDLSL------- 1517
Cdd:PRK03918  373 ELERLKkrltglTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvCGRELteehrke 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1518 LLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEK-EARAKESETS 1596
Cdd:PRK03918  453 LLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLKKYNLEElEKKAEEYEKL 530

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1597 LYENNKLHGRVVLLEEEIQRLrvcsEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAET-AQLAANIETLKS---DFAA 1672
Cdd:PRK03918  531 KEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELEPfynEYLE 606

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1673 LSKSKLELQELHscltKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLR-----NEEALKEKEKLEESYFILQKEI 1747
Cdd:PRK03918  607 LKDAEKELEREE----KELKKLEEELDKAFEELAETEKRLEELRKELEELEKKyseeeYEELREEYLELSRELAGLRAEL 682

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382 1748 SQLAQTNSHISANLLESQSENRTLRKDKSKLTL-------------KIRELETLHSFTA-AQTAEDAMQIMEQMTKEK 1811
Cdd:PRK03918  683 EELEKRREEIKKTLEKLKEELEEREKAKKELEKlekalerveelreKVKKYKALLKERAlSKVGEIASEIFEELTEGK 760
PTZ00121 PTZ00121
MAEBL; Provisional
 1348-2061 3.14e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 3.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1348 EEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNE-----KITYLTSEKE 1422
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKaeeakKADEAKKKAE 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1423 VACQKVAKLKKQQDSLlKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERK 1502
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEA-KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1503 KENQELTSSKCDLslllKEAQDAKKNLEKEHTSmiqakdnlnAELKTCCCEKNMllrdglnlQEECQKLNEEIREIQQTL 1582
Cdd:PTZ00121 1405 KKADELKKAAAAK----KKADEAKKKAEEKKKA---------DEAKKKAEEAKK--------ADEAKKKAEEAKKAEEAK 1463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1583 ILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQtenftltqEKTNSEQKVEEIIKEKELLSAETAQLAAn 1662
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEEAK---KADEAKKKAEEAKKKADEAK--------KAAEAKKKADEAKKAEEAKKADEAKKAE- 1531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1663 iETLKSDFAALSKSKLELQELhscltKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEA-LKEKEKLEESYF 1741
Cdd:PTZ00121 1532 -EAKKADEAKKAEEKKKADEL-----KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArIEEVMKLYEEEK 1605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1742 ILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDA-MQIMEQMTKEKTETLASLED 1820
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAeEAKKAEEDKKKAEEAKKAEE 1685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1821 TKQTNArlqnELDTLKENNLKTVEELNKSKEllsVENQKMEEFKKEIETLKQaaaqKSQQLSALQEENVKLAEELGRTRD 1900
Cdd:PTZ00121 1686 DEKKAA----EALKKEAEEAKKAEELKKKEA---EEKKKAEELKKAEEENKI----KAEEAKKEAEEDKKKAEEAKKDEE 1754

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1901 EVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASlqKSISLTSALLTEKDAELEKLRNEVTVLRGENA 1980
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI--KDIFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1981 TAKSLHSVVQTLESDKVKlelkvknlelQLKENKRQLSSSSGNTDAQA-------EEDERAQESQQMIDFLNSVIVDLQR 2053
Cdd:PTZ00121 1833 KEVADSKNMQLEEADAFE----------KHKFNKNNENGEDGNKEADFnkekdlkEDDEEEIEEADEIEKIDKDDIEREI 1902


                  ....*...
gi 568937382 2054 KNQDLKMK 2061
Cdd:PTZ00121 1903 PNNNMAGK 1910
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 416-1252 3.37e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   416 VEAADREKVELLNQLEEEKRKVEDLQFRVEEesitkgdlevatVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdv 495
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDE------------KRQQLERLRREREKAERYQALLKEKREYEGYE----- 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   496 dmslsLLQEISALQEKLEAIhtdhQGEMTSLKEHFgareEAFQKEIkalhtatEKLSKENESLRSKLDHANKENSDvial 575
Cdd:TIGR02169  228 -----LLKEKEALERQKEAI----ERQLASLEEEL----EKLTEEI-------SELEKRLEEIEQLLEELNKKIKD---- 283

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   576 wksKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRldyqhEIESLQSKQDSERSAHAKEMETMQ---AKL 652
Cdd:TIGR02169  284 ---LGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA-----KLEAEIDKLLAEIEELEREIEEERkrrDKL 355

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   653 MKIIKEKEDSLEAVKARLDSAE----------DQHLVEMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAV 722
Cdd:TIGR02169  356 TEEYAELKEELEDLRAELEEVDkefaetrdelKDYREKLEKLKREINELK---RELDRLQEELQRLSEELADLNAAIAGI 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   723 KEKLLDLDA----LRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQV 798
Cdd:TIGR02169  433 EAKINELEEekedKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAV 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   799 KETLEK----------ELQTLKEKFASTSEEAVSAqtRMQDTV---------------------------NKLHQKEeqf 841
Cdd:TIGR02169  513 EEVLKAsiqgvhgtvaQLGSVGERYATAIEVAAGN--RLNNVVveddavakeaiellkrrkagratflplNKMRDER--- 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   842 nvlsSELEKLREN-LTDMEAKFKEKDDREDQLVK--------------AKE--------KLENDIAE------------- 885
Cdd:TIGR02169  588 ----RDLSILSEDgVIGFAVDLVEFDPKYEPAFKyvfgdtlvvedieaARRlmgkyrmvTLEGELFEksgamtggsrapr 663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   886 -IMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTK-------ANENASFLQKSIGEVTLKAEQSQQQAArKHEEEKKEL 957
Cdd:TIGR02169  664 gGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRienrldeLSQELSDASRKIGEIEKEIEQLEQEEE-KLKERLEEL 742

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   958 EEKLLELEKKMETSYNQCQDLKAKYEkASSETKTKHEEILQNLQKMLADTE-DKLKAAQEANRDLMQDMEELKTQADKA- 1035
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIE-ELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKl 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1036 KSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSvnetlhlEKERV 1115
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK-------ERDEL 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1116 SEEKQVAEKRYQQEHRDREslvaEREKLLKEINAAQEELLKmhmENDSLEASKVSMQVLIEELrfckdklmAMSEKARAE 1195
Cdd:TIGR02169  895 EAQLRELERKIEELEAQIE----KKRKRLSELKAKLEALEE---ELSEIEDPKGEDEEIPEEE--------LSLEDVQAE 959

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1196 KEHLEGQVKKLTAENLVLVKDKDDVIQK---LQSAYEELVKDQKALVQEIEDLTTEKKSA 1252
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEVLKRldeLKEKRAKLEEERKAILERIEEYEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1518-1879 3.53e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 3.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1518 LLKEAQDAKKNLEKEHTSMIQAKDnLNAELKTCccEKNMLLRDGLNLQEECQKLNEEIREiQQTLILEKEARAKESETSL 1597
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKE-LKAELREL--ELALLVLRLEELREELEELQEELKE-AEEELEELTAELQELEEKL 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1598 YENNKLHGRvvlLEEEIqrlrvcsEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSdfaalskSK 1677
Cdd:TIGR02168  270 EELRLEVSE---LEEEI-------EELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES-------KL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1678 LELQElhscltkILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHI 1757
Cdd:TIGR02168  333 DELAE-------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1758 SANLLESQSENRTLRKDKSKLTLKIREletlhsftaAQTAEDAMQImEQMTKEKTETLASLEDTKQTNARLQNELDTLKE 1837
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEE---------AELKELQAEL-EELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 568937382  1838 NNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQ 1879
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG 517
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 355-1160 9.06e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 9.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   355 ALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKvELLNQLEEEK 434
Cdd:pfam02463  228 YLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEE-ELKSELLKLE 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   435 RKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLEsskppgdvDMSLSLLQEISALQEKLEA 514
Cdd:pfam02463  307 RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE--------ELEKLQEKLEQLEEELLAK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   515 IHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEEL 594
Cdd:pfam02463  379 KKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQEL 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   595 KvsfsKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKAR----- 669
Cdd:pfam02463  459 K----LLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGrlgdl 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   670 -----LDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELE 744
Cdd:pfam02463  535 gvaveNYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLE 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   745 TLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 824
Cdd:pfam02463  615 ADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEI 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   825 TRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIaeimKMSGDNSSQLTKMNDEL 904
Cdd:pfam02463  695 LRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEE----KSRLKKEEKEEEKSELS 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   905 RLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEK 984
Cdd:pfam02463  771 LKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEK 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   985 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1064
Cdd:pfam02463  851 LAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL 930

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1065 LyaQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLL 1144
Cdd:pfam02463  931 L--KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLI 1008

                          810
                   ....*....|....*.
gi 568937382  1145 KEINAAQEELLKMHME 1160
Cdd:pfam02463 1009 RAIIEETCQRLKEFLE 1024
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1395-1927 1.88e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.65  E-value: 1.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1395 KLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQngdlLADRESSIKTIGDLRRKYDQEA 1474
Cdd:TIGR04523  128 KLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKE----KLNIQKNIDKIKNKLLKLELLL 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1475 TNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEK 1554
Cdd:TIGR04523  204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKI 283

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1555 NMLLRDGLNLQEECQKLN----EEIREIQQTLILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQTENFT 1630
Cdd:TIGR04523  284 KELEKQLNQLKSEISDLNnqkeQDWNKELKSELKNQEKKLEEIQNQISQNNK---IISQLNEQISQLKKELTNSESENSE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1631 LTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQ 1710
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1711 DNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHS 1790
Cdd:TIGR04523  441 EIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1791 F--TAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA------RLQNELDTLKENNLKTVEELNKSKELLSVENQKMEE 1862
Cdd:TIGR04523  521 SlkEKIEKLESEKKEKESKISDLEDELNKDDFELKKENlekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382  1863 FKKEIETLKQAAAQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKSLP 1927
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSII---KNIKSKKNKLKQEVKQIKETIKEIRNKWP 662
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
421-888 2.13e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 2.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  421 REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELR---RRLESSKPPGDVDM 497
Cdd:PRK03918  217 PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvKELKELKEKAEEYI 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  498 SLS-----LLQEISALQEKLEAIHTDHQG------EMTSLKEHFGAREEAFqKEIKALHTATEKLSKENESLRSKLDHAN 566
Cdd:PRK03918  297 KLSefyeeYLDELREIEKRLSRLEEEINGieerikELEEKEERLEELKKKL-KELEKRLEELEERHELYEEAKAKKEELE 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  567 KENSDVIALWKSKLETAIASHQQAMEELKVSFSK---GIGTDSAEFAELKTQIERL-----------RLDYQHEIESLQS 632
Cdd:PRK03918  376 RLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKitaRIGELKKEIKELKKAIEELkkakgkcpvcgRELTEEHRKELLE 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  633 KQDSERSAHAKEMETMQAKLMKIIKEKedsleaVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKE--LEVLQAKYTEQSE 710
Cdd:PRK03918  456 EYTAELKRIEKELKEIEEKERKLRKEL------RELEKVLKKESELIKLKELAEQLKELEEKLKKynLEELEKKAEEYEK 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  711 V---IGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTG 787
Cdd:PRK03918  530 LkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKD 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  788 LQDSLnqvnqvkETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNV-----LSSELEKLRENLTDMEAKF 862
Cdd:PRK03918  610 AEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeyeeLREEYLELSRELAGLRAEL 682

                         490       500
                  ....*....|....*....|....*.
gi 568937382  863 KEKDDREDQLVKAKEKLENDIAEIMK 888
Cdd:PRK03918  683 EELEKRREEIKKTLEKLKEELEEREK 708
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
353-853 2.96e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 2.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  353 QEALKEKQQhIEQLLAERDLeRAEVAKATSHVGEIEQELALARDGHDQHVLEL-EAKMDQLRTMVEAADREKVELLNQLE 431
Cdd:COG4913   242 EALEDAREQ-IELLEPIREL-AERYAAARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLEAELERLEARLD 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  432 EEKRKVEDLQFRVEEES-ITKGDLEvatvsekSRIMELEKDLALRAQEVAELRRRLES--SKPPGDVDMSLSLLQEISAL 508
Cdd:COG4913   320 ALREELDELEAQIRGNGgDRLEQLE-------REIERLERELEERERRRARLEALLAAlgLPLPASAEEFAALRAEAAAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  509 QEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALhtateklSKENESLRSkldhaNKEN--SDVIALwKSKLETAIAS 586
Cdd:COG4913   393 LEALEEELEALEEALAEAE----AALRDLRRELREL-------EAEIASLER-----RKSNipARLLAL-RDALAEALGL 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  587 HQQAM----EELKVSFSKGIGTDSAE----------------FAELKTQIERL----RLDYQH-------------EIES 629
Cdd:COG4913   456 DEAELpfvgELIEVRPEEERWRGAIErvlggfaltllvppehYAAALRWVNRLhlrgRLVYERvrtglpdperprlDPDS 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  630 LQSKQDSERSAHAKEMETMQAKLMKIIK-EKEDSLE----AV-------------------------------KARLDSA 673
Cdd:COG4913   536 LAGKLDFKPHPFRAWLEAELGRRFDYVCvDSPEELRrhprAItragqvkgngtrhekddrrrirsryvlgfdnRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  674 EDQhLVEMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETLR 747
Cdd:COG4913   616 EAE-LAELEEELAEAEER---LEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  748 QQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTRm 827
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR- 768

                         570       580
                  ....*....|....*....|....*.
gi 568937382  828 QDTVNKLHQKEEQFNVLSSELEKLRE 853
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMR 794
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1000-1582 3.57e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.98  E-value: 3.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1000 LQKMLADTEDKLKAAQEANRDLMQDM-----EELKTQADKAKSLTYLLTSAKKEIEVMSEELRglkSEKQLYAQEANALK 1074
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDRIEQLiseheVEITGLTEKASSARSQANSIQSQLEIIQEQAR---NQNSMYMRQLSDLE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1075 LEKGSLLSKLIEVETkitlLQEDQQKlwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRES--LVAEREKLLKEINAAQE 1152
Cdd:pfam15921  324 STVSQLRSELREAKR----MYEDKIE--------ELEKQLVLANSELTEARTERDQFSQESgnLDDQLQKLLADLHKREK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1153 ELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELV 1232
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1233 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQfekdtlrqgqeKLSASLEATLQVKQLLSTEA 1312
Cdd:pfam15921  472 STKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-----------KLRSRVDLKLQELQHLKNEG 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1313 ETLR-TQLDCASKALRKAELD--MRQLQTSNSSLTKLLEEIKTCRAITDSECIQLlhEKEslaASERTLLAEKEELLSEN 1389
Cdd:pfam15921  541 DHLRnVQTECEALKLQMAEKDkvIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL--EKE---INDRRLELQEFKILKDK 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1390 RiiTEKLSKQSEEVARLEMglnEKITYLTSEKEvACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKtigDLRRK 1469
Cdd:pfam15921  616 K--DAKIRELEARVSDLEL---EKVKLVNAGSE-RLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR---NFRNK 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1470 YDQ-EATNRRIVMQEKmKLLGNIDALKKELQERKKEN-----------QELTSSKCDLSLLLKEAQ---DAKKNLEKEHT 1534
Cdd:pfam15921  687 SEEmETTTNKLKMQLK-SAQSELEQTRNTLKSMEGSDghamkvamgmqKQITAKRGQIDALQSKIQfleEAMTNANKEKH 765

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 568937382  1535 SMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTL 1582
Cdd:pfam15921  766 FLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
PTZ00121 PTZ00121
MAEBL; Provisional
 368-920 4.32e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 4.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  368 AERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEE 447
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED 1403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  448 SitKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPPGDVDmslsllqeiSALQEKLEAIHTDHQGEMTSLK 527
Cdd:PTZ00121 1404 K--KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK---------KKAEEAKKAEEAKKKAEEAKKA 1472

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  528 EHFGAREEAFQKeikalhtaTEKLSKENESLRSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSFSKGiGTDSA 607
Cdd:PTZ00121 1473 DEAKKKAEEAKK--------ADEAKKKAEEAKKKADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAK-KADEA 1539

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  608 EFAELKTQIERLRldYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEmedTLNK 687
Cdd:PTZ00121 1540 KKAEEKKKADELK--KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE---EAKK 1614

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  688 LQEAEIKVKELEvlqakytEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAE 767
Cdd:PTZ00121 1615 AEEAKIKAEELK-------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  768 SSKANSITKELQEKELVLTGLQDSLNQVNQVKEtLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSE 847
Cdd:PTZ00121 1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE-LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937382  848 LEKLRENLTDMEAKFKEKDDREDqlvkakEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTK 920
Cdd:PTZ00121 1767 EKKAEEIRKEKEAVIEEELDEED------EKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK 1833
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 733-1487 6.85e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 58.06  E-value: 6.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   733 RKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTglqdslnqvnQVKETLEKELQTLKEk 812
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYH----------ERKQVLEKELKHLRE- 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   813 fastseeavsAQTRMQDTVNKLHQKEEQFNvlssELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEND-----IAEIM 887
Cdd:TIGR00618  234 ----------ALQQTQQSHAYLTQKREAQE----EQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHI 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   888 KMSGDNSSQLTKMNDELRLKERSVE-ELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEK 966
Cdd:TIGR00618  300 KAVTQIEQQAQRIHTELQSKMRSRAkLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQ 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   967 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLK-AAQEANRDLMQDMEELKTQAdkaksLTYLLTSA 1045
Cdd:TIGR00618  380 HIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQlAHAKKQQELQQRYAELCAAA-----ITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1046 KKEIEVMSEELRGLKSEKQLYAQEANALKLEKgsllSKLIEVETKITLLQEDQQKLwsVNETLHLEKERV-SEEKQVAEK 1124
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQET----RKKAVVLARLLELQEEPCPL--CGSCIHPNPARQdIDNPGPLTR 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1125 RYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVK 1204
Cdd:TIGR00618  529 RMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1205 KLTAENLVLVK------DKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaEKQMSLDNTCLTLKAERENLLQT-- 1276
Cdd:TIGR00618  609 MLACEQHALLRklqpeqDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR--EHALSIRVLPKELLASRQLALQKmq 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1277 --NRDLQFEKDTLRQGQEKLSASLEATL-------QVKQLLSTEAETLRTQLDCASKALRKAELDMR---QLQTSNSSLT 1344
Cdd:TIGR00618  687 seKEQLTYWKEMLAQCQTLLRELETHIEeydrefnEIENASSSLGSDLAAREDALNQSLKELMHQARtvlKARTEAHFNN 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1345 KLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENR--IITEKLSKQSEEVARLEMGLN--EKITYLTSE 1420
Cdd:TIGR00618  767 NEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIpsDEDILNLQCETLVQEEEQFLSrlEEKSATLGE 846

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382  1421 KEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKL 1487
Cdd:TIGR00618  847 ITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSE 913
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
613-1209 7.85e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  613 KTQIERLRLDYQHEIESLQS----KQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKL 688
Cdd:PRK02224  175 RLGVERVLSDQRGSLDQLKAqieeKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREEL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  689 QEAEikvKELEVLQAKYTEqsevignftsqlsAVKEKlldlDALRKansegklELETLRQQLEGAEKQIKNLETERNAES 768
Cdd:PRK02224  254 ETLE---AEIEDLRETIAE-------------TERER----EELAE-------EVRDLRERLEELEEERDDLLAEAGLDD 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  769 SKANSITKELQEKELVLTGLQDSLNQV-------NQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 841
Cdd:PRK02224  307 ADAEAVEARREELEDRDEELRDRLEECrvaaqahNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  842 NVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAeimkmsgdnssqltkmndELRLKERSVEElqlkltKA 921
Cdd:PRK02224  387 EELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREA------------------ELEATLRTARE------RV 442

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  922 NENASFLqksigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-----KHEEI 996
Cdd:PRK02224  443 EEAEALL-----EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrieRLEER 517

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  997 LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQLYAQEANAL-KL 1075
Cdd:PRK02224  518 REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA---AEAEEEAEEAREEVAELNSKLAELKERIESLeRI 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1076 EkgSLLSKLIEVETKITLLQEDQQKLWSVN----ETLHLEKERVSE-EKQVAEKRYQQEHRDRESLVAEREKLLKEINAA 1150
Cdd:PRK02224  595 R--TLLAAIADAEDEIERLREKREALAELNderrERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDEL 672

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382 1151 QEellkmhmENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARA------EKEHLEGQVKKLTAE 1209
Cdd:PRK02224  673 RE-------ERDDLQAEIGAVENELEELEELRERREALENRVEAlealydEAEELESMYGDLRAE 730
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 644-1097 1.04e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   644 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQLSAVK 723
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ----LNQLKDEQNKI---KKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   724 EKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQ--------------IKNLETERNAESSKANSITKELQEKELVLTG 787
Cdd:TIGR04523  295 SEISDLNNQKEQDwnKELKSELKNQEKKLEEIQNQisqnnkiisqlneqISQLKKELTNSESENSEKQRELEEKQNEIEK 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   788 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 867
Cdd:TIGR04523  375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   868 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAA 947
Cdd:TIGR04523  455 IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKK 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   948 RKHEeekkeleekllelekkmETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKmLADTEDKLKAAQEANRDLMQDME- 1026
Cdd:TIGR04523  535 EKES-----------------KISDLEDELNKDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEk 596

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382  1027 -------ELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQED 1097
Cdd:TIGR04523  597 ekkdlikEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTK 674
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
800-1329 1.12e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  800 ETLEkELQTLKEKFASTSEEAvsAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 879
Cdd:COG4913   252 ELLE-PIRELAERYAAARERL--AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  880 ENDIAEImkmSGDNSSQLtkmndelrlkERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 959
Cdd:COG4913   329 EAQIRGN---GGDRLEQL----------EREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  960 KLLELEKKMETSYnqcqDLKAKYEKASSETKTKHEEIL----------QNLQKMLADTEDKLKAAQEANR---DLMQDME 1026
Cdd:COG4913   396 LEEELEALEEALA----EAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEALGLDEAELPfvgELIEVRP 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1027 E-----------LKTQAdkakslTYLLTSAKKEIEV--------MSEELRGLKSEKQLyaQEANALKLEKGSLLSKLIEV 1087
Cdd:COG4913   472 EeerwrgaiervLGGFA------LTLLVPPEHYAAAlrwvnrlhLRGRLVYERVRTGL--PDPERPRLDPDSLAGKLDFK 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1088 ETKIT--LLQE--DQQKLWSVN--ETLHLEKERVSEEKQVAEKRYQQEHRDR-----------------ESLVAEREKLL 1144
Cdd:COG4913   544 PHPFRawLEAElgRRFDYVCVDspEELRRHPRAITRAGQVKGNGTRHEKDDRrrirsryvlgfdnraklAALEAELAELE 623

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1145 KEINAAQEELLKMHMENDSLEASKVSMQVLiEELRFCKDKLMAmsekARAEKEHLEGQVKKLTAENlvlvkdkdDVIQKL 1224
Cdd:COG4913   624 EELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVAS----AEREIAELEAELERLDASS--------DDLAAL 690

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1225 QSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEatlQV 1304
Cdd:COG4913   691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER---EL 767

                         570       580
                  ....*....|....*....|....*
gi 568937382 1305 KQLLSTEAETLRTQLDCASKALRKA 1329
Cdd:COG4913   768 RENLEERIDALRARLNRAEEELERA 792
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 903-1740 1.28e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.29  E-value: 1.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   903 ELRLKERSVEELqLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKheeekkeLEEKLLELEKKMETSYNQCQDLKAKY 982
Cdd:pfam02463  164 GSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLN 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   983 EKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTylltsakKEIEVMSEELRGLKSE 1062
Cdd:pfam02463  236 EERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA-------KEEEELKSELLKLERR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1063 KQLYAQEANALKLEKGSLLSKLIEVETKITllqEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREK 1142
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIE---ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1143 LLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKL-TAENLVLVKDKDDVI 1221
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEkEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1222 QKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEAT 1301
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1302 LQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQlLHEKESLAASERTLLAE 1381
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ-LDKATLEADEDDKRAKV 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1382 KEELLSENRIITEKLSK-----QSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADR 1456
Cdd:pfam02463  625 VEGILKDTELTKLKESAkakesGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1457 ESSIKTIgdLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSK------CDLSLLLKEAQDAKKNLE 1530
Cdd:pfam02463  705 EQREKEE--LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKkeekeeEKSELSLKEKELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1531 KEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVV-L 1609
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEeE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1610 LEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAalsKSKLELQELHSCLTK 1689
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK---EEAEILLKYEEEPEE 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 568937382  1690 ILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESY 1740
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2134-2150 1.56e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.56e-07
                           10
                   ....*....|....*..
gi 568937382  2134 RPYCEICEMFGHWATNC 2150
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 708-926 1.80e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 1.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  708 QSEVIGNFTSQLSAVKEKLL----DLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKEL 783
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAelekELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  784 VLTGLQDSLNQVNQvkeTLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 863
Cdd:COG4942    98 ELEAQKEELAELLR---ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937382  864 EKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 926
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1716-2092 2.71e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1716 LAEKREMMLRNEEALKEKEKLEESYFILQkeiSQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1795
Cdd:COG5022   805 LLGSRKEYRSYLACIIKLQKTIKREKKLR---ETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELA- 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1796 taedamqimEQMTKEKTETLASLEDTKQTNARLQNEL---------DTLKENNLKTvEELNKSKELL---SVENQKMEEF 1863
Cdd:COG5022   881 ---------ERQLQELKIDVKSISSLKLVNLELESEIielkkslssDLIENLEFKT-ELIARLKKLLnniDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1864 KK-----EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLR------ 1932
Cdd:COG5022   951 VKlpelnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEvaelqs 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1933 ESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlk 2011
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV--- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 2012 eNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKK 2091
Cdd:COG5022  1104 -TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRL 1182


                  .
gi 568937382 2092 K 2092
Cdd:COG5022  1183 Y 1183
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1307-1873 3.06e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 55.52  E-value: 3.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1307 LLSTEAETLRTQLDCASKalRKAELDMRqlqtsnsslTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELL 1386
Cdd:pfam05557   31 ELEKKASALKRQLDRESD--RNQELQKR---------IRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1387 SENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNgDLLADRESSIKtigDL 1466
Cdd:pfam05557  100 ADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQ-SSLAEAEQRIK---EL 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1467 RRKYDQEATNRRIVMQEKMKLLgNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQA------K 1540
Cdd:pfam05557  176 EFEIQSQEQDSEIVKNSKSELA-RIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREEKYREEAatleleK 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1541 DNLNAELKTCcceKNMLLRDGLNLQEEcQKLNEEIREIQQTLILEKEarakESETSLYENNKLHGRVVLLEEEIQRLRVC 1620
Cdd:pfam05557  255 EKLEQELQSW---VKLAQDTGLNLRSP-EDLSRRIEQLQQREIVLKE----ENSSLTSSARQLEKARRELEQELAQYLKK 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1621 SEQLQTENftltqeKTNSEQKvEEIIKEKELLSAETAQLAANIETLKSDFaALSKSKLELQELHSCLTKILDDLRlNHEV 1700
Cdd:pfam05557  327 IEDLNKKL------KRHKALV-RRLQRRVLLLTKERDGYRAILESYDKEL-TMSNYSPQLLERIEEAEDMTQKMQ-AHNE 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1701 ALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFIlQKEISQLAQTNSHISA---------NLLESQSENRTL 1771
Cdd:pfam05557  398 EMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYS-KEEVDSLRRKLETLELerqrlreqkNELEMELERRCL 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1772 RKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLkenNLKTVEELNKSKE 1851
Cdd:pfam05557  477 QGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTM---NFKEVLDLRKELE 553

                          570       580
                   ....*....|....*....|...
gi 568937382  1852 LLSVENQKMEE-FKKEIETLKQA 1873
Cdd:pfam05557  554 SAELKNQRLKEvFQAKIQEFRDV 576
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
409-910 4.34e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 4.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  409 MDQLRTMVEA-ADREKVELLNQLEEEKRKVEDLQFRVEEEsitkgdlevatvseKSRIMELEKDLALRAQEVAELRRRLE 487
Cdd:PRK02224  189 LDQLKAQIEEkEEKDLHERLNGLESELAELDEEIERYEEQ--------------REQARETRDEADEVLEEHEERREELE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  488 SskppgdvdmslsLLQEISALQEKLEAIHTDhqgemtslkehfgarEEAFQKEIKALHTATEKLSKENESLRSKLDHANK 567
Cdd:PRK02224  255 T------------LEAEIEDLRETIAETERE---------------REELAEEVRDLRERLEELEEERDDLLAEAGLDDA 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  568 EnSDVIALWKSKLETAIASHQQAMEELKVSFSkgigtdsaefaELKTQIERLRldyqHEIESLQSKQDSERSAhAKEMET 647
Cdd:PRK02224  308 D-AEAVEARREELEDRDEELRDRLEECRVAAQ-----------AHNEEAESLR----EDADDLEERAEELREE-AAELES 370

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  648 MQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLL 727
Cdd:PRK02224  371 ELEEAREAVEDRREEIEELEEEIEELRER----FGDAPVDLGNAE---DFLEELREERDELREREAELEATLRTARERVE 443

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  728 DLDALRKA-----------NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSItKELQEKElvltglqDSLNQVN 796
Cdd:PRK02224  444 EAEALLEAgkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAE-------DRIERLE 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  797 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAK 876
Cdd:PRK02224  516 ERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIR 595

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 568937382  877 EKLEnDIAEIMKMSG---DNSSQLTKMNDELR--LKERS 910
Cdd:PRK02224  596 TLLA-AIADAEDEIErlrEKREALAELNDERRerLAEKR 633
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 985-2062 4.98e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.12  E-value: 4.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   985 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMeelKTQADKAKSLTYLLTSAKKEIEVMSEELRGlKSEKQ 1064
Cdd:pfam15921  128 AMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDS---NTQIEQLRKMMLSHEGVLQEIRSILVDFEE-ASGKK 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1065 LYAQEANALKLEK--GSLLSKLI-EVETKITLLQedqQKLWSVNETLhlekERVSEEKQVAEKRYQQEHRDR-ESLVAER 1140
Cdd:pfam15921  204 IYEHDSMSTMHFRslGSAISKILrELDTEISYLK---GRIFPVEDQL----EALKSESQNKIELLLQQHQDRiEQLISEH 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1141 EKllkEINAAQEELLKMHMENDSLEAskvsmqvlieelrfckdKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDV 1220
Cdd:pfam15921  277 EV---EITGLTEKASSARSQANSIQS-----------------QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1221 IQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAErenLLQTNRDLQFEKD-TLRQGQEKLSASLE 1299
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD---LHKREKELSLEKEqNKRLWDRDTGNSIT 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1300 ATLQVKQLLSTEAETLRtqLDCASKALR-----KAELDMRQLQTSNSSLTKLleeiktcraitDSECIQLLHEKESLAAS 1374
Cdd:pfam15921  414 IDHLRRELDDRNMEVQR--LEALLKAMKsecqgQMERQMAAIQGKNESLEKV-----------SSLTAQLESTKEMLRKV 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1375 ERTLLAEKEELLSENRIITEkLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLK---EKSALELQNGD 1451
Cdd:pfam15921  481 VEELTAKKMTLESSERTVSD-LTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQMAE 559

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1452 LLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLlgnidalKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEK 1531
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL-------EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLEL 632

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1532 EHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIReiqqtlILEKEARAKESETSLyENNKLhgrvvlle 1611
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE------VLKRNFRNKSEEMET-TTNKL-------- 697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1612 eEIQRLRVCSEQLQTENfTLTQEKTNSEQKVEEIIKEKELLSAETAQ---LAANIETLKSDFAALSKSKLELQELHSclt 1688
Cdd:pfam15921  698 -KMQLKSAQSELEQTRN-TLKSMEGSDGHAMKVAMGMQKQITAKRGQidaLQSKIQFLEEAMTNANKEKHFLKEEKN--- 772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1689 kilddlrlnhevALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEEsyFILQKEISQLAQTNSHIsanllesQSEN 1768
Cdd:pfam15921  773 ------------KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME--VALDKASLQFAECQDII-------QRQE 831

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1769 RTLRKDKSKLTLKIRELETlhsftAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQN---ELDTLKENNLKTVEE 1845
Cdd:pfam15921  832 QESVRLKLQHTLDVKELQG-----PGYTSNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHhsrKTNALKEDPTRDLKQ 906

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1846 LnkSKELLSVENQkmeefkkeietlkqaaaQKSQQLSALQEENVklAEELGRTRDEVTS---HQKLEEERSVLNNQLLEM 1922
Cdd:pfam15921  907 L--LQELRSVINE-----------------EPTVQLSKAEDKGR--APSLGALDDRVRDciiESSLRSDICHSSSNSLQT 965

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1923 KKSLPSNTLRESEFRKDADEekaslqksISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELK 2002
Cdd:pfam15921  966 EGSKSSETCSREPVLLHAGE--------LEDPSSCFTFPSTASPSVKNSASRSFHSSPKKSPVHSLLTSSAEGSIGSSSQ 1037

                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937382  2003 VKNlelqlkenKRQLSSSSGNTDAQAEEDERAQES----QQMIDFLNSVIVDLQRKNQDLKMKV 2062
Cdd:pfam15921 1038 YRS--------AKTIHSPDSVKDSQSLPIETTGKTcrklQNRLESLQTLVEDLQLKNQAMSSMI 1093
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1189-2002 5.37e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 5.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1189 SEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKA 1268
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1269 ERENLLQTNRDLQFEKDTL-----RQGQEKLsasLEATLQVKQLLSTEAETLRTQLDcASKALRKAELDMRQLQTSNSSL 1343
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLgeeeqLRVKEKI---GELEAEIASLERSIAEKERELED-AEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1344 TKLLEEIKTCRAitdseciQLLHEKESLAASERTLLA----------------------------EKEELLSENRIITEK 1395
Cdd:TIGR02169  342 EREIEEERKRRD-------KLTEEYAELKEELEDLRAeleevdkefaetrdelkdyrekleklkrEINELKRELDRLQEE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1396 LSKQSEEVARLEM---GLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQ 1472
Cdd:TIGR02169  415 LQRLSEELADLNAaiaGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1473 EATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEA-------------QDAKKNLE--KEHTSMI 1537
Cdd:TIGR02169  495 AEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAagnrlnnvvveddAVAKEAIEllKRRKAGR 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1538 QAKDNLNaELKTCCCEKNMLLRDG-----LNLQEECQKLNEEIREI-QQTLILEKEARAKES---------ETSLYE--- 1599
Cdd:TIGR02169  575 ATFLPLN-KMRDERRDLSILSEDGvigfaVDLVEFDPKYEPAFKYVfGDTLVVEDIEAARRLmgkyrmvtlEGELFEksg 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1600 --------NNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDfa 1671
Cdd:TIGR02169  654 amtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE-- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1672 aLSKSKLELQELHSCLTKIlddlrlnhEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEK--LEESYFILQKEISQ 1749
Cdd:TIGR02169  732 -EEKLKERLEELEEDLSSL--------EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlSHSRIPEIQAELSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1750 LAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKektetlasLEDTKQTNARLQ 1829
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK--------KEELEEELEELE 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1830 NELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLE 1909
Cdd:TIGR02169  875 AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLE 954

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1910 EERSVLNNQLLEMKKSLPSNTLRESEFR---KDADEEKASLQKSISLTSALLtEKDAELEKLRNEVtVLRGENATAKSLH 1986
Cdd:TIGR02169  955 DVQAELQRVEEEIRALEPVNMLAIQEYEevlKRLDELKEKRAKLEEERKAIL-ERIEEYEKKKREV-FMEAFEAINENFN 1032

                          890
                   ....*....|....*.
gi 568937382  1987 SVVQTLESDKVKLELK 2002
Cdd:TIGR02169 1033 EIFAELSGGTGELILE 1048
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 427-945 6.64e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 6.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   427 LNQLEEEKRKVEDLQFRVEEEsitkgdlevatvseksrIMELEKDLALRAQEVAELRRRLESSKppgdvDMSLSLLQEIS 506
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTE-----------------IKKKEKELEKLNNKYNDLKKQKEELE-----NELNLLEKEKL 183

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   507 ALQEKLEAIHTDHqgemtSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSD---VIALWKSKLETA 583
Cdd:TIGR04523  184 NIQKNIDKIKNKL-----LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEkttEISNTQTQLNQL 258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   584 IASHQQAMEELK------VSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIK 657
Cdd:TIGR04523  259 KDEQNKIKKQLSekqkelEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   658 EKEDSLEAVKARLDSAEDqhlvemeDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDalrKANS 737
Cdd:TIGR04523  339 QLNEQISQLKKELTNSES-------ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQE---KLNQ 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   738 EGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKekfasts 817
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIK------- 481

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   818 eeavsaqtrmqdtvNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 897
Cdd:TIGR04523  482 --------------QNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDEL 547

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 568937382   898 TKMNDELR--LKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQ 945
Cdd:TIGR04523  548 NKDDFELKkeNLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 797-1664 8.07e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 8.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   797 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLT---DMEAKFKEKDDREDQLV 873
Cdd:TIGR00606  203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSkimKLDNEIKALKSRKKQME 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   874 KAKEKLENDIAEIMKMSGDNSSQLTKMND-ELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEE 952
Cdd:TIGR00606  283 KDNSELELKMEKVFQGTDEQLNDLYHNHQrTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   953 EKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEA-----------NRDL 1021
Cdd:TIGR00606  363 IRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQadeirdekkglGRTI 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1022 MQDMEELKTQADKAKSLTYL---LTSAKKEIEVMSEELRglKSEKQLYAQEANA----LKLEKGSLLSKLIEVETKITLL 1094
Cdd:TIGR00606  443 ELKKEILEKKQEELKFVIKElqqLEGSSDRILELDQELR--KAERELSKAEKNSltetLKKEVKSLQNEKADLDRKLRKL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1095 QEDQQKL----WSVNETLHLEKERVSEEKQVAEKRYQQEHR---------DRESLVAEREKLLKEINAAQEELLKMHMEN 1161
Cdd:TIGR00606  521 DQEMEQLnhhtTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEltsllgyfpNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1162 DSLEASK----VSMQVLIEELRFCKDKLMAM--SEKARAEKEHLEGQVKKLTAENLVL----------VKDKDDVIQKLQ 1225
Cdd:TIGR00606  601 ASLEQNKnhinNELESKEEQLSSYEDKLFDVcgSQDEESDLERLKEEIEKSSKQRAMLagatavysqfITQLTDENQSCC 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1226 SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVK 1305
Cdd:TIGR00606  681 PVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1306 QLLSTEAETLRTQLDCASKALRKAELdmrqLQTSNSSLTKLLEEIKTCRAITDSECIQLlhEKESLAASERTLLAEKEEL 1385
Cdd:TIGR00606  761 QRLKNDIEEQETLLGTIMPEEESAKV----CLTDVTIMERFQMELKDVERKIAQQAAKL--QGSDLDRTVQQVNQEKQEK 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1386 LSENRIITEKLskqsEEVARLEMGLNEKITYLTSEkevaCQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGD 1465
Cdd:TIGR00606  835 QHELDTVVSKI----ELNRKLIQDQQEQIQHLKSK----TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKD 906

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1466 LRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKE-NQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIqakDNLN 1544
Cdd:TIGR00606  907 AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETEL---NTVN 983

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1545 AELKTCCCEKNMLLRDGLNLQE--ECQKLNEEIREIQQTL-ILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCS 1621
Cdd:TIGR00606  984 AQLEECEKHQEKINEDMRLMRQdiDTQKIQERWLQDNLTLrKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENI 1063

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 568937382  1622 EQL-QTENFTLTQEKTNSEQKV--EEIIKEKELLSAETAQLAANIE 1664
Cdd:TIGR00606 1064 DLIkRNHVLALGRQKGYEKEIKhfKKELREPQFRDAEEKYREMMIV 1109
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 980-1553 8.25e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.46  E-value: 8.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   980 AKYEKASSETKTKHEEiLQNLQKMLADTE----DKLKAAQEANRDLMQDMEELKTQ-ADKAKSLTYLLTSAKKEIEVMSE 1054
Cdd:pfam12128  244 TKLQQEFNTLESAELR-LSHLHFGYKSDEtliaSRQEERQETSAELNQLLRTLDDQwKEKRDELNGELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1055 ELRGLKSEKQLYAQ---EANALKLEK-GSLLSKLIEVETKITLLQEDQQKLWSVNETLhlEKERVSEEKQVAEKRYQQEH 1130
Cdd:pfam12128  323 ELEALEDQHGAFLDadiETAAADQEQlPSWQSELENLEERLKALTGKHQDVTAKYNRR--RSKIKEQNNRDIAGIKDKLA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1131 RDREslvaEREKLLKEINA---AQEELLKMHMENDSLEASKVSMQVL--IEELRFCKDKLMAMSE-------------KA 1192
Cdd:pfam12128  401 KIRE----ARDRQLAVAEDdlqALESELREQLEAGKLEFNEEEYRLKsrLGELKLRLNQATATPElllqlenfderieRA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1193 RAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQE-----------IEDLTTEKKSAAEKQMSLDN 1261
Cdd:pfam12128  477 REEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELelqlfpqagtlLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1262 TCLTLK------------AERENLLQTNRDLQ--------FEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDC 1321
Cdd:pfam12128  557 PELLHRtdldpevwdgsvGGELNLYGVKLDLKridvpewaASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1322 ASK-------ALRKAELDMRQLQTSNSSLT-KLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRiiT 1393
Cdd:pfam12128  637 ASReetfartALKNARLDLRRLFDEKQSEKdKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREAR--T 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1394 EKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKyDQE 1473
Cdd:pfam12128  715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVR-RQE 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1474 ATNRRIVMQEKMKLlgNIDALKKELQERKKENQELtssKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCE 1553
Cdd:pfam12128  794 VLRYFDWYQETWLQ--RRPRLATQLSNIERAISEL---QQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE 868
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1076-1820 1.70e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1076 EKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL 1155
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1156 KMHMENDSLEASKVSMQVLIEELRFCKDklmAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQ 1235
Cdd:TIGR00618  244 YLTQKREAQEEQLKKQQLLKQLRARIEE---LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1236 KALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQF-----EKDTLRQGQEKLSASLEATLQVKQLLST 1310
Cdd:TIGR00618  321 RSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIreiscQQHTLTQHIHTLQQQKTTLTQKLQSLCK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1311 EAETLRTQLDCASkALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENR 1390
Cdd:TIGR00618  401 ELDILQREQATID-TRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1391 IITEKLSKQSEEVARLEMGLNEKityltsEKEVACQKVAKLKKQQDSLLKEKSALELQNGDllaDRESSIKTIGDLRRKY 1470
Cdd:TIGR00618  480 QIHLQETRKKAVVLARLLELQEE------PCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE---QTYAQLETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1471 DQEATNRRIVMQEKMKLlgnidalkkELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKehtsmiqakdnlNAELKTC 1550
Cdd:TIGR00618  551 LTSERKQRASLKEQMQE---------IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK------------LSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1551 CCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVV--LLEEEIQRLRVCSEQLQTEN 1628
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIrvLPKELLASRQLALQKMQSEK 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1629 FTLTQEKtnseqkvEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEV 1708
Cdd:TIGR00618  690 EQLTYWK-------EMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1709 lQDNKNLLAEKREMMLRNEEALK-EKEKLEESYFILQKEISQL-AQTNSHISANLLESQSENRTLRKDKSKLTLKIREL- 1785
Cdd:TIGR00618  763 -HFNNNEEVTAALQTGAELSHLAaEIQFFNRLREEDTHLLKTLeAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKs 841

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 568937382  1786 ETLHSFTAAQTA-EDAMQIMEQMTKEKTETLASLED 1820
Cdd:TIGR00618  842 ATLGEITHQLLKyEECSKQLAQLTQEQAKIIQLSDK 877
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 742-948 1.72e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  742 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAV 821
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  822 SAQTRMQDTVNKLHQKEEQ----FNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 897
Cdd:COG4942   101 AQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568937382  898 TKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAAR 948
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PTZ00121 PTZ00121
MAEBL; Provisional
 736-1546 2.21e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  736 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFAS 815
Cdd:PTZ00121 1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEAR 1134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  816 TSEEAVSAQ-TRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNS 894
Cdd:PTZ00121 1135 KAEDARKAEeARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKA 1214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  895 SQLTKMNDELRLKE-RSVEELQLK---LTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKME- 969
Cdd:PTZ00121 1215 EEARKAEDAKKAEAvKKAEEAKKDaeeAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADe 1294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  970 ----TSYNQCQDLKAKYEKA--SSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLT 1043
Cdd:PTZ00121 1295 akkaEEKKKADEAKKKAEEAkkADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1044 SAKKEIEVMSEelrglKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAE 1123
Cdd:PTZ00121 1375 EAKKKADAAKK-----KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1124 KRYQQEHRDRESLV--AEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVL--IEELRFCKDKLMAMSEKARAEKEHL 1199
Cdd:PTZ00121 1450 KKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkAAEAKKKADEAKKAEEAKKADEAKK 1529

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1200 EGQVKKLTAENLVLVKDKDDVIQKLqsayEELVKdqkalVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRD 1279
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKA----EELKK-----AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1280 LQFEKdtlRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDS 1359
Cdd:PTZ00121 1601 YEEEK---KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1360 ECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDsll 1439
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE--- 1754

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1440 KEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKllgNIDALKKELQERKKENQE-LTSSKCDLSLL 1518
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLvINDSKEMEDSA 1831

                         810       820
                  ....*....|....*....|....*...
gi 568937382 1519 LKEAQDAKKNLEKEHTSMIQAKDNLNAE 1546
Cdd:PTZ00121 1832 IKEVADSKNMQLEEADAFEKHKFNKNNE 1859
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-803 3.39e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHD----------QHVLELE 406
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeaveARREELE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  407 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRL 486
Cdd:PRK02224  321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERF 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  487 ESSkpPGDVDMSLSLLQEisaLQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ-----------KEIK-ALHTAT------ 548
Cdd:PRK02224  401 GDA--PVDLGNAEDFLEE---LREERDELREREAELEATLRTARERVEEAEAlleagkcpecgQPVEgSPHVETieedre 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  549 --EKLSKENESLRSKLDHANKENSDVIALwkSKLETAIASHQQAMEELkvsfSKGIGTDSAEFAELKTQIERLRldyqHE 626
Cdd:PRK02224  476 rvEELEAELEDLEEEVEEVEERLERAEDL--VEAEDRIERLEERREDL----EELIAERRETIEEKRERAEELR----ER 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  627 IESLQSKQDSERSAHAKEMETMQAKLMKiIKEKEDSLEAVKARLDSAEDqhlveMEDTLNKLQEAEikvKELEVLQAKYT 706
Cdd:PRK02224  546 AAELEAEAEEKREAAAEAEEEAEEAREE-VAELNSKLAELKERIESLER-----IRTLLAAIADAE---DEIERLREKRE 616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  707 EQSEVIGNFTSQLSAVKEKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkelv 784
Cdd:PRK02224  617 ALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEE---- 692

                         490
                  ....*....|....*....
gi 568937382  785 LTGLQDSLNQVNQVKETLE 803
Cdd:PRK02224  693 LEELRERREALENRVEALE 711
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
665-886 3.96e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 3.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  665 AVKARLDSAEDQ--HLVEMEDTLNKLQEaeiKVKELEVLQAKYTEqsevignftsqLSAVKEKLLDLDALRKAnsegkLE 742
Cdd:COG4913   222 DTFEAADALVEHfdDLERAHEALEDARE---QIELLEPIRELAER-----------YAAARERLAELEYLRAA-----LR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  743 LETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQV-NQVKETLEKELQTLKEKFastsEEAV 821
Cdd:COG4913   283 LWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLEREL----EERE 358

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937382  822 SAQTRMQDTVNKLHQK----EEQFNVLSSELEKLRENLTDMEAKFKEK----DDREDQLVKAKEKLENDIAEI 886
Cdd:COG4913   359 RRRARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEAlaeaEAALRDLRRELRELEAEIASL 431
PRK11281 PRK11281
mechanosensitive channel MscK;
740-947 4.13e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.22  E-value: 4.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  740 KLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKeLVLTGLQDSLNQVNQvketlekELQTLKEKFASTSEE 819
Cdd:PRK11281   79 KEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLST-LSLRQLESRLAQTLD-------QLQNAQNDLAEYNSQ 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  820 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimKMSGDNSSQLTk 899
Cdd:PRK11281  151 LVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-------RKSLEGNTQLQ- 222

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 568937382  900 mndELRLKERsvEELQLKLTKANENASFLQKSIGEVTLkaEQSQQQAA 947
Cdd:PRK11281  223 ---DLLQKQR--DYLTARIQRLEHQLQLLQEAINSKRL--TLSEKTVQ 263
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1558-2012 4.23e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 4.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1558 LRDGLN-LQEECQKLNEEIREIQQTLILEKEARAKESETsLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKT 1636
Cdd:PRK02224  204 LHERLNgLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREELETLEAEIEDLRETIAETEREREELAEEVR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1637 NSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQElhSCLTKILDDLRLNHEV-ALTERAEVLQD-NKN 1714
Cdd:PRK02224  283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD--RLEECRVAAQAHNEEAeSLREDADDLEErAEE 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1715 LLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSfTAA 1794
Cdd:PRK02224  361 LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR-TAR 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1795 QTAEDAMQIMEQ-------MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQ------KME 1861
Cdd:PRK02224  440 ERVEEAEALLEAgkcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRierleeRRE 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1862 EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTS-HQKLEEERSV---LNNQLLEMKKSLPS-NTLRES-E 1935
Cdd:PRK02224  520 DLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEaEEEAEEAREEvaeLNSKLAELKERIESlERIRTLlA 599

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382 1936 FRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKslhsvVQTLESDKVKLELKVKNLELQLKE 2012
Cdd:PRK02224  600 AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAR-----IEEAREDKERAEEYLEQVEEKLDE 671
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1631-1883 4.90e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 51.83  E-value: 4.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1631 LTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEvalTERAEVLQ 1710
Cdd:PLN02939  147 LNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGA---TEGLCVHS 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1711 DNKNLLAEKRE-MMLRNE-EALKEK----EKLEESYFILQKEISQLAQTNSHISANLLESQSenrtlrkDKSKL-TLKI- 1782
Cdd:PLN02939  224 LSKELDVLKEEnMLLKDDiQFLKAElievAETEERVFKLEKERSLLDASLRELESKFIVAQE-------DVSKLsPLQYd 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1783 ---RELETLHSF--TAAQTAEDAMQIMEQMT--KEKTETL-ASLEDTKQTnaRLQNELDTLKENNLKTVEE-LNKS-KEL 1852
Cdd:PLN02939  297 cwwEKVENLQDLldRATNQVEKAALVLDQNQdlRDKVDKLeASLKEANVS--KFSSYKVELLQQKLKLLEErLQASdHEI 374

                         250       260       270
                  ....*....|....*....|....*....|....
gi 568937382 1853 LS---VENQKMEEFKKEIETLKQAAAQKSQQLSA 1883
Cdd:PLN02939  375 HSyiqLYQESIKEFQDTLSKLKEESKKRSLEHPA 408
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1519-2020 5.31e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 5.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1519 LKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTL------ILEKEARAKE 1592
Cdd:TIGR04523   49 LKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIkndkeqKNKLEVELNK 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1593 SETSLYENNKLHGRVVlleEEIQRLRVCSEQLQTENFTLTQEKTNSEqkveeiiKEKELLSAETAQLAANIETLKSDFAA 1672
Cdd:TIGR04523  129 LEKQKKENKKNIDKFL---TEIKKKEKELEKLNNKYNDLKKQKEELE-------NELNLLEKEKLNIQKNIDKIKNKLLK 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1673 LSKSKLELQ---ELHSCLTKILDDLRlNHEVALTERAEVLQDNKNllaEKREMMLRNEEALKE-KEKLEESYFILQKEIS 1748
Cdd:TIGR04523  199 LELLLSNLKkkiQKNKSLESQISELK-KQNNQLKDNIEKKQQEIN---EKTTEISNTQTQLNQlKDEQNKIKKQLSEKQK 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1749 QLAQTNSHIS---ANLLESQSENRTLRKDKSKLTLKireleTLHSFTAAQTAEdamqiMEQMTKEKTETLASLEDTKQTN 1825
Cdd:TIGR04523  275 ELEQNNKKIKeleKQLNQLKSEISDLNNQKEQDWNK-----ELKSELKNQEKK-----LEEIQNQISQNNKIISQLNEQI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1826 ARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL--------------KQAAAQKSQQLSALQEENVKL 1891
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLesqindleskiqnqEKLNQQKDEQIKKLQQEKELL 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1892 AEELGRTRDEVTSHQK----LEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKsislTSALLTEKDAELEK 1967
Cdd:TIGR04523  425 EKEIERLKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ----KQKELKSKEKELKK 500

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382  1968 LRNEVTVLRGENATAK----SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 2020
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTkkisSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE 557
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 729-885 5.38e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 5.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  729 LDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKE--TLEKEL 806
Cdd:COG1579    19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKEI 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937382  807 QTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLtdmEAKFKEKDDREDQLVKAKEKLENDIAE 885
Cdd:COG1579    99 ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL---DEELAELEAELEELEAEREELAAKIPP 174
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1031-1255 5.92e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1031 QADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1110
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1111 EKERVSEE-KQVAEKRYQQEHRDRESLV---------AEREKLLKEINAAQEELLkmhmenDSLEASKVSMQVLIEELRF 1180
Cdd:COG4942    98 ELEAQKEElAELLRALYRLGRQPPLALLlspedfldaVRRLQYLKYLAPARREQA------EELRADLAELAALRAELEA 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382 1181 CKDKLMAMSEKARAEKEHLEgqvkKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEK 1255
Cdd:COG4942   172 ERAELEALLAELEEERAALE----ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 644-1444 7.36e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.33  E-value: 7.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   644 EMETMQAKLMKIIKEKEDSLEAVKARLDSAED---QHLVEMEDTLNKLQEAEIKVKELEVLQAKYteqsevignftsQLS 720
Cdd:pfam01576   58 EAEEMRARLAARKQELEEILHELESRLEEEEErsqQLQNEKKKMQQHIQDLEEQLDEEEAARQKL------------QLE 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   721 AV----KEKLLDLDALRKANSEGKLELEtlRQQLEgaeKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN 796
Cdd:pfam01576  126 KVtteaKIKKLEEDILLLEDQNSKLSKE--RKLLE---ERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   797 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAK 876
Cdd:pfam01576  201 KGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE---LQAALARLEEETAQKNNALKKIRELEAQISELQ 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   877 EKLENDIA---EIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEE 953
Cdd:pfam01576  278 EDLESERAarnKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   954 KKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-------------KHEEILQNLQKMLADTE-------DKLKA 1013
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTlqqakqdsehkrkKLEGQLQELQARLSESErqraelaEKLSK 437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1014 AQEANRDLMQDMEELKTQADK-AKSLTYLLTSAKKEIEVMSEELRglksEKQLYAQEANALKLEKGSLLSKLIEVETKit 1092
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKlSKDVSSLESQLQDTQELLQEETR----QKLNLSTRLRQLEDERNSLQEQLEEEEEA-- 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1093 lLQEDQQKLWSVNETLHLEKERVSEEKQVAE------KRYQQE----HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1162
Cdd:pfam01576  512 -KRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkKRLQRElealTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLD 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1163 S-------LEASKVSMQVLIEELRFCKDKLMAMSEKARAE---------------------KEHLEGQVKKLTAENLVLV 1214
Cdd:pfam01576  591 HqrqlvsnLEKKQKKFDQMLAEEKAISARYAEERDRAEAEareketralslaraleealeaKEELERTNKQLRAEMEDLV 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1215 KDKDDV------IQKLQSAYEELVKDQKALVQEIEDlttEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLR 1288
Cdd:pfam01576  671 SSKDDVgknvheLERSKRALEQQVEEMKTQLEELED---ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQL 747

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1289 QGQ-EKLSASLE-------ATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRA---IT 1357
Cdd:pfam01576  748 VKQvRELEAELEderkqraQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDeilAQ 827

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1358 DSEC--------IQLLHEKESLAASER---TLLAEKEELLSENRIITEKLSKQSEEVARLE---MGLNEKITYLTSEKEV 1423
Cdd:pfam01576  828 SKESekklknleAELLQLQEDLAASERarrQAQQERDELADEIASGASGKSALQDEKRRLEariAQLEEELEEEQSNTEL 907

                          890       900
                   ....*....|....*....|.
gi 568937382  1424 ACQKVAKLKKQQDSLLKEKSA 1444
Cdd:pfam01576  908 LNDRLRKSTLQVEQLTTELAA 928
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
409-1024 8.75e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 8.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  409 MDQLRTMVEAAD--REKVELLNQLEEEKRKVEDLQfrveeESITKGDLEVATVseksRIMELEKDLALRAQEVAELRRRL 486
Cdd:COG4913   234 FDDLERAHEALEdaREQIELLEPIRELAERYAAAR-----ERLAELEYLRAAL----RLWFAQRRLELLEAELEELRAEL 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  487 ESskppgdvdmslsLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKAlhtateklskenesLRSKLDhan 566
Cdd:COG4913   305 AR------------LEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIER--------------LERELE--- 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  567 kensdvialwksKLETAIASHQQAMEELKVSFSkgigTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHakeme 646
Cdd:COG4913   356 ------------ERERRRARLEALLAALGLPLP----ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAL----- 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  647 tmqAKLMKIIKEKEDSLEAVKARlDSAEDQHLVEMEDTLNklQEAEIKVKEL----EVLQAKYTEQS-----E-VIGNFT 716
Cdd:COG4913   415 ---RDLRRELRELEAEIASLERR-KSNIPARLLALRDALA--EALGLDEAELpfvgELIEVRPEEERwrgaiErVLGGFA 488

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  717 SQLsAVKEKLLDlDALRKANSEgKLEletLRQQLEGAEKQIKNLETERnaesSKANSITKELQEKELVLTG-LQDSLNQV 795
Cdd:COG4913   489 LTL-LVPPEHYA-AALRWVNRL-HLR---GRLVYERVRTGLPDPERPR----LDPDSLAGKLDFKPHPFRAwLEAELGRR 558

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  796 NQVK--ETLEkELQtlKEKFASTSEEAVSAQTRM----------------QDTVNKLHQKEEQFNVLSSELEKLRENLTD 857
Cdd:COG4913   559 FDYVcvDSPE-ELR--RHPRAITRAGQVKGNGTRhekddrrrirsryvlgFDNRAKLAALEAELAELEEELAEAEERLEA 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  858 MEAKFKEKDDREDQLVKAKEKL--ENDIAEIMKMSGDNSSQLTKM---NDELRLKERSVEELQLKLTKANENASFLQKSI 932
Cdd:COG4913   636 LEAELDALQERREALQRLAEYSwdEIDVASAEREIAELEAELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEI 715

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  933 GEVTLKAEQSQQQAARKHEEEKKELEEKLLELEkkmetsynqcQDLKAKYEKASSETKTKheEILQNLQKMLADTEDKLK 1012
Cdd:COG4913   716 GRLEKELEQAEEELDELQDRLEAAEDLARLELR----------ALLEERFAAALGDAVER--ELRENLEERIDALRARLN 783

                         650
                  ....*....|..
gi 568937382 1013 AAQEANRDLMQD 1024
Cdd:COG4913   784 RAEEELERAMRA 795
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1375-2080 9.48e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 9.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1375 ERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLA 1454
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1455 DRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHT 1534
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1535 SMIQAKDNLNAELKTccCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLhgrvvLLEEEI 1614
Cdd:pfam02463  332 KEKEEIEELEKELKE--LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-----LKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1615 QRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKS---------KLELQELHS 1685
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELElkksedllkETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1686 CLTKILDDLRLNHEVALTERAE--------------------------------------------VLQDNKNLLAEKRE 1721
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARsglkvllalikdgvggriisahgrlgdlgvavenykvaistaviVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1722 MMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1801
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1802 QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQL 1881
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1882 SALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKSISLTSALLTEK 1961
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1962 DAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMI 2041
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 568937382  2042 DFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSY 2080
Cdd:pfam02463  885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1490-2015 1.09e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1490 NIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCcceknmllrdgLNLQEECQ 1569
Cdd:PRK01156  184 NIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNEL-----------SSLEDMKN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1570 KLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLqtENFTLTQEKTNSE-QKVEEIIKE 1648
Cdd:PRK01156  253 RYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDI--ENKKQILSNIDAEiNKYHAIIKK 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1649 KELLSAETAQLaaniETLKSDFAALSKSKLELQELHS----------CLTKILDDLRLNHEVALTERAEVLqdnKNLLAE 1718
Cdd:PRK01156  331 LSVLQKDYNDY----IKKKSRYDDLNNQILELEGYEMdynsylksieSLKKKIEEYSKNIERMSAFISEIL---KIQEID 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1719 KREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHIS--ANLLESQS------------ENRTLRK----DKSKLTL 1780
Cdd:PRK01156  404 PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSrnMEMLNGQSvcpvcgttlgeeKSNHIINhyneKKSRLEE 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1781 KIRELETLHSfTAAQTAEDAMQIMEQMTKEKTETLAS----LEDTKQTNARLQNELDTLKENNLKTVEELNKSKEL-LSV 1855
Cdd:PRK01156  484 KIREIEIEVK-DIDEKIVDLKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLkLED 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1856 ENQKMEEFKK--------EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSH-QKLEEERSVLNNQ--LLEMKK 1924
Cdd:PRK01156  563 LDSKRTSWLNalavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKynEIQENK 642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1925 SLPSNTLRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENATAKSLHSVVQTLESDKVKLELKVK 2004
Cdd:PRK01156  643 ILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINELSDRIN 719

                         570
                  ....*....|.
gi 568937382 2005 NLELQLKENKR 2015
Cdd:PRK01156  720 DINETLESMKK 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 788-1039 1.44e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  788 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 867
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  868 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMndeLRLKERSVEELQLKLTKanenasfLQKSIGEVTLKAEQSQQQAA 947
Cdd:COG4942   105 ELAELLRALYRLGRQPPLALLLSPEDFLDAVRR---LQYLKYLAPARREQAEE-------LRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  948 RKheeekkeleekllelekkmETSYNQCQDLKAKYEKAssetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEE 1027
Cdd:COG4942   175 EL-------------------EALLAELEEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|..
gi 568937382 1028 LKTQADKAKSLT 1039
Cdd:COG4942   232 LEAEAAAAAERT 243
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1690-2030 1.94e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1690 ILDDLRLNHEVALTERAEVLQdNKNLLAEKREmmLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENR 1769
Cdd:TIGR02169  192 IIDEKRQQLERLRREREKAER-YQALLKEKRE--YEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1770 TLRKDKSKLTLKIRELetlhsftaaqTAEDAMQIMEQMTkektETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKS 1849
Cdd:TIGR02169  269 EIEQLLEELNKKIKDL----------GEEEQLRVKEKIG----ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1850 KELLSVENQKMEEFKKEIETLKQAAAQKSQQLSAL----QEENVKLAEELGRTRDEVTSHQKLEEERsvlnNQLLEMKKS 1925
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEKLKREI----NELKRELDR 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1926 LPSNTLRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTlESDKVKLELKVKN 2005
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE-EYDRVEKELSKLQ 489

                          330       340
                   ....*....|....*....|....*
gi 568937382  2006 LELQLKENKRQLSSSSGNTDAQAEE 2030
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEE 514
PRK11281 PRK11281
mechanosensitive channel MscK;
1824-2048 2.09e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.91  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1824 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1896
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1897 --RTRDEVTSHQKLEEERSVLNNQLLEMKKSLpsntlresefrKDADEEKASLQKSISLTSALLTEKDAELEKLRNEvtv 1974
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDL-----------AEYNSQLVSLQTQPERAQAALYANSQRLQQIRNL--- 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382 1975 LRGENATAKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEED---ERAQESQQMIDFLNSVI 2048
Cdd:PRK11281  179 LKGGKVGGKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDyltARIQRLEHQLQLLQEAI 250
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 689-1190 2.19e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 49.75  E-value: 2.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   689 QEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAES 768
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   769 SKANSITKElqEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSEL 848
Cdd:pfam07111  143 EEIQRLHQE--QLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   849 EKLRENLTDM---EAKFKEKDDREDQLVKAKEKLENDIAEI---MKMSGDNSSQLTKM----NDELRLKERSVEELQLKL 918
Cdd:pfam07111  221 ESLRKYVGEQvppEVHSQTWELERQELLDTMQHLQEDRADLqatVELLQVRVQSLTHMlalqEEELTRKIQPSDSLEPEF 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   919 TKANEN--ASFLQKSIG-EVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQC-QDLKAKYEKASSETKT--- 991
Cdd:pfam07111  301 PKKCRSllNRWREKVFAlMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRAlQDKAAEVEVERMSAKGlqm 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   992 ---KHEEILQNLQKMLADTEDKLK----AAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVmseeLRGLKSEKQ 1064
Cdd:pfam07111  381 elsRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHT----IKGLMARKV 456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1065 LYAQeanaLKLEKGSLLSKLIEVETKITLLQEDqqklwsvnetLHLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKL 1143
Cdd:pfam07111  457 ALAQ----LRQESCPPPPPAPPVDADLSLELEQ----------LREERNRLDAELQLSAHLIQQEvGRAREQGEAERQQL 522

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568937382  1144 LK-------EINAAQEELLKMHMEndsLEASKVSMQVLIEELRFCKDKLMAMSE 1190
Cdd:pfam07111  523 SEvaqqleqELQRAQESLASVGQQ---LEVARQGQQESTEEAASLRQELTQQQE 573
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
355-528 2.74e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.47  E-value: 2.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  355 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD 420
Cdd:COG2433   347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  421 REKVELLNQLEEEKRKVEDLQFRVEEESitkgdlevatvSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdmsls 500
Cdd:COG2433   427 AEVEELEAELEEKDERIERLERELSEAR-----------SEERREIRKDREISRLDREIERLERELEEER---------- 485

                         170       180       190
                  ....*....|....*....|....*....|..
gi 568937382  501 llQEISALQEKLE----AIHTDHQGEMTSLKE 528
Cdd:COG2433   486 --ERIEELKRKLErlkeLWKLEHSGELVPVKV 515
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 771-1352 3.02e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.25  E-value: 3.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   771 ANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEK 850
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   851 LRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQK 930
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   931 SIGEVTLKAEQSQQ-----QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLA 1005
Cdd:TIGR04523  188 NIDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1006 DTEDKLKAAQEANRDLMQDMEELKT------------QADKAKSLTYLLTSAKKEIEVMSEELRG-------LKSEKQLY 1066
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQlkseisdlnnqkEQDWNKELKSELKNQEKKLEEIQNQISQnnkiisqLNEQISQL 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1067 AQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKE 1146
Cdd:TIGR04523  348 KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1147 INAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKD----KLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQ 1222
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTREsletQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1223 kLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAE--RENLLQTNRDLQFEKDTLRQGQEKLSASLEA 1300
Cdd:TIGR04523  508 -LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382  1301 TLQVKQLLSTE--------------AETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKT 1352
Cdd:TIGR04523  587 KQELIDQKEKEkkdlikeieekekkISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 404-1076 3.20e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.40  E-value: 3.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   404 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELR 483
Cdd:pfam01576   72 ELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLS 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   484 RrlESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLkehfgarEEAFQKEikalhtatEKLSKENESLRSKLD 563
Cdd:pfam01576  152 K--ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDL-------EERLKKE--------EKGRQELEKAKRKLE 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   564 HANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKgigtdSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAK 643
Cdd:pfam01576  215 GESTDLQEQIAELQAQIAELRAQLAKKEEELQAALAR-----LEEETAQKNNALKKIRELEAQISELQEDLESERAARNK 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   644 EMET---MQAKLMKIIKEKEDSLE--AVKARLDSAEDQHLVEMEDTLnklqEAEIKVKELEVLQAKyTEQSEVIGNFTSQ 718
Cdd:pfam01576  290 AEKQrrdLGEELEALKTELEDTLDttAAQQELRSKREQEVTELKKAL----EEETRSHEAQLQEMR-QKHTQALEELTEQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   719 LSAVKEKLLDLD----ALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQ 794
Cdd:pfam01576  365 LEQAKRNKANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELES 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   795 VNQVKETLEKELQTLkekfastSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVK 874
Cdd:pfam01576  445 VSSLLNEAEGKNIKL-------SKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVER 517

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   875 AKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQS--QQQAARKHEE 952
Cdd:pfam01576  518 QLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvDLDHQRQLVS 597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   953 EKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLadteDKLKAAQEANRDLMQDMEELKTQA 1032
Cdd:pfam01576  598 NLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEAL----EAKEELERTNKQLRAEMEDLVSSK 673

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*.
gi 568937382  1033 DKAKSLTYLLTSAKKEIEVMSEELRGL--KSEKQLYAQEANALKLE 1076
Cdd:pfam01576  674 DDVGKNVHELERSKRALEQQVEEMKTQleELEDELQATEDAKLRLE 719
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1704-1897 3.31e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1704 ERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIR 1783
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1784 E-------------LETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSK 1850
Cdd:COG4942   108 EllralyrlgrqppLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 568937382 1851 ELLSvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGR 1897
Cdd:COG4942   188 AALE---ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 351-568 3.52e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARdghdQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  431 EEEKRKVEDL---QFRVEEESITKGDLEVATVSEKSRIMELEKDLA-LRAQEVAELRRRLESSKppgdvdmslSLLQEIS 506
Cdd:COG4942   100 EAQKEELAELlraLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLApARREQAEELRADLAELA---------ALRAELE 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382  507 ALQEKLEAIHTDHQGEMTSLKEHFGAREEA---FQKEIKALHTATEKLSKENESLRSKLDHANKE 568
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLlarLEKELAELAAELAELQQEAEELEALIARLEAE 235
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 555-1872 3.96e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 49.28  E-value: 3.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   555 NESLRSKLDHANKENSDVIALWKsKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQ---IERLRLDYQHEIESLQ 631
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWK-KLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEiiyINKLKLELKEKIKNIS 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   632 SKQDSERSAhakemetmqAKLMKIIKEKEDSLEAVkARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSev 711
Cdd:TIGR01612  614 DKNEYIKKA---------IDLKKIIENNNAYIDEL-AKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELS-- 681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   712 ignftsqlSAVKEKLLDldalrkaNSEGKLELETLRQQLEGAEKQIKNLETE------RNAESSKANSITKELQEKELVL 785
Cdd:TIGR01612  682 --------SIVKENAID-------NTEDKAKLDDLKSKIDKEYDKIQNMETAtvelhlSNIENKKNELLDIIVEIKKHIH 746

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   786 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNklhQKEEQFNVLSSELEKLRENLTDMEAKFKEK 865
Cdd:TIGR01612  747 GEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKN---HYNDQINIDNIKDEDAKQNYDKSKEYIKTI 823

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   866 DDREDQLVKAKEKLENDIAEIMK-----MSGDNS---------SQLTKMNDELRlKERSVEELQLKLTKANENASFLQ-- 929
Cdd:TIGR01612  824 SIKEDEIFKIINEMKFMKDDFLNkvdkfINFENNckekidsehEQFAELTNKIK-AEISDDKLNDYEKKFNDSKSLINei 902

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   930 -KSIGEV------------TLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEI 996
Cdd:TIGR01612  903 nKSIEEEyqnintlkkvdeYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKA 982

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   997 LQNLQkmLADTEDKlkaaqeaNRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEanalkle 1076
Cdd:TIGR01612  983 FKDAS--LNDYEAK-------NNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIE------- 1046

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1077 kgsllsklIEVETKITLLQEDQQKLWSVN-ETLHLE--KERVSEEKQVAEKRYQQEHRDRESLVAERE-KLLKEINAAQE 1152
Cdd:TIGR01612 1047 --------IAIHTSIYNIIDEIEKEIGKNiELLNKEilEEAEINITNFNEIKEKLKHYNFDDFGKEENiKYADEINKIKD 1118

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1153 ELLKMHMEND----SLEASKVSMQVLIEELRFCKDKLMAMSEKArAEKEHLEGQVKKLtaENLVLVKDKD----DVIQKL 1224
Cdd:TIGR01612 1119 DIKNLDQKIDhhikALEEIKKKSENYIDEIKAQINDLEDVADKA-ISNDDPEEIEKKI--ENIVTKIDKKkniyDEIKKL 1195

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1225 QSAYEELVKDQ------------------------------------KALVQEIEDLTTEKKSAAEKQMSLdNTCLTLKA 1268
Cdd:TIGR01612 1196 LNEIAEIEKDKtsleevkginlsygknlgklflekideekkksehmiKAMEAYIEDLDEIKEKSPEIENEM-GIEMDIKA 1274

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1269 ERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAEtlrtqLDCASKALRKAELDMrqlQTSNSSLTKLLE 1348
Cdd:TIGR01612 1275 EMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESD-----INDIKKELQKNLLDA---QKHNSDINLYLN 1346

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1349 EIKTCRAITDSECIQLLHE--KESLAASERTLLAEKEELLSenriiTEKLSKQSEEVARLEMgLNEKITYLTSEKEV-AC 1425
Cdd:TIGR01612 1347 EIANIYNILKLNKIKKIIDevKEYTKEIEENNKNIKDELDK-----SEKLIKKIKDDINLEE-CKSKIESTLDDKDIdEC 1420

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1426 qkVAKLKKQQDSLLKEKSalelQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQ-EKMKLLGNIDALKKELQERKKE 1504
Cdd:TIGR01612 1421 --IKKIKELKNHILSEES----NIDTYFKNADENNENVLLLFKNIEMADNKSQHILKiKKDNATNDHDFNINELKEHIDK 1494

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1505 nqeltSSKCDlslllKEAQDAKKNLEKEHTSMIQAKDNLNAELKTcccEKNMLLRDGLN-LQEECQKLNEEIREIQQTLI 1583
Cdd:TIGR01612 1495 -----SKGCK-----DEADKNAKAIEKNKELFEQYKKDVTELLNK---YSALAIKNKFAkTKKDSEIIIKEIKDAHKKFI 1561

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1584 LekearakESETSLYENNKLHGRVVLLEEEIQRLRVCSE-----QLQTENFTLTQEK-TNSEQKVEEIIKEKELLSAETA 1657
Cdd:TIGR01612 1562 L-------EAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKaaidiQLSLENFENKFLKiSDIKKKINDCLKETESIEKKIS 1634

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1658 QLAAN-------------------IETLKSDFAALSKSKLELQELHSCLTKILDDL---RLNHEVALTERAevlqdnknl 1715
Cdd:TIGR01612 1635 SFSIDsqdtelkengdnlnslqefLESLKDQKKNIEDKKKELDELDSEIEKIEIDVdqhKKNYEIGIIEKI--------- 1705

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1716 laekremmlrNEEALKEKEKLEESYFILQKEISQLAqtnSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1795
Cdd:TIGR01612 1706 ----------KEIAIANKEEIESIKELIEPTIENLI---SSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAG- 1771

                         1370      1380      1390      1400      1410      1420      1430
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382  1796 taedamqIMEQMTKEKTetlaSLEDTKQTNARLQNELdtlkennLKTVEELNKSKELLsvENQKMEEFKKEIETLKQ 1872
Cdd:TIGR01612 1772 -------CLETVSKEPI----TYDEIKNTRINAQNEF-------LKIIEIEKKSKSYL--DDIEAKEFDRIINHFKK 1828
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 496-1178 6.04e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   496 DMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEhfgaREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL 575
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHE----RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   576 WK-----SKLETAIASHQQAMEELKVSFSKgigtdsAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQA 650
Cdd:TIGR00618  263 KQlrariEELRAQEAVLEETQERINRARKA------APLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQ 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   651 KLMkiIKEKEDSLEAVKARLDSAEDQHLVEM--EDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLD 728
Cdd:TIGR00618  337 QSS--IEEQRRLLQTLHSQEIHIRDAHEVATsiREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDT 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   729 LDA--------LRKANSEGKLELETLRQQLEGAEKQIKnLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKE 800
Cdd:TIGR00618  415 RTSafrdlqgqLAHAKKQQELQQRYAELCAAAITCTAQ-CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   801 TLEKELQTLKEKF-ASTSEEAVSAQ---------TRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDRED 870
Cdd:TIGR00618  494 ARLLELQEEPCPLcGSCIHPNPARQdidnpgpltRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFS 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   871 QLVKAKEKLENDIAEIMKMSgDNSSQLTKMNDELRLKERsvEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAA--R 948
Cdd:TIGR00618  574 ILTQCDNRSKEDIPNLQNIT-VRLQDLTEKLSEAEDMLA--CEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTAlhA 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   949 KHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKaaqEANRDLMQDMEEL 1028
Cdd:TIGR00618  651 LQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIE---EYDREFNEIENAS 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1029 KTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLI-EVETKITLLQEDQQKLWSVNET 1107
Cdd:TIGR00618  728 SSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAaEIQFFNRLREEDTHLLKTLEAE 807

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937382  1108 LHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEEL 1178
Cdd:TIGR00618  808 IGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 402-1245 7.45e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 7.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   402 VLELEAKMDQLRTMVEA--ADREKVELLNQLEEEK--RKVEDLQF------------RVEEESITKGDLEVATVSEKSRI 465
Cdd:pfam12128  188 MHSKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQveHWIRDIQAiagimkirpeftKLQQEFNTLESAELRLSHLHFGY 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   466 MELEKDLALRAQEVAELRRRLESSKPPGDVDMSLS---LLQEISAL-------QEKLEAIHTDH----QGEMTSLKEH-- 529
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrdeLNGELSAAdaavakdRSELEALEDQHgaflDADIETAAADqe 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   530 ----FGAREEAFQKEIKALHTATEKLSKENESLRSKLDhanKENSDVIALWKSKLE----------TAIASHQQAME-EL 594
Cdd:pfam12128  348 qlpsWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDKLAkireardrqlAVAEDDLQALEsEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   595 KVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhaKEMETMQAKLMKIIKEKEDsLEAVKARLDSAE 674
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD--ERIERAREEQEAANAEVER-LQSELRQARKRR 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   675 DQHLVemedtlnKLQEAEIKVKELEvlqakyteqsevignftSQLSAVKEKLLDldalrkanSEGKLeLETLRQQLEGAE 754
Cdd:pfam12128  502 DQASE-------ALRQASRRLEERQ-----------------SALDELELQLFP--------QAGTL-LHFLRKEAPDWE 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   755 KQI-KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVnQVKETLEKElQTLKEKFASTSEEAVSAQTRMQdtvnk 833
Cdd:pfam12128  549 QSIgKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRI-DVPEWAASE-EELRERLDKAEEALQSAREKQA----- 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   834 lhQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKmsgdnssqltkmnDELRLKERSVEE 913
Cdd:pfam12128  622 --AAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALA-------------ERKDSANERLNS 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   914 LqlkltkanenasflqksigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKH 993
Cdd:pfam12128  687 L-------------------EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKA 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   994 EeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAksltylltsAKKEIEVMSEElrglKSEKQLYAQEANAL 1073
Cdd:pfam12128  748 E--LKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERI---------AVRRQEVLRYF----DWYQETWLQRRPRL 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1074 KLEKGSLLSKLIEVETKITLLQEDQQKLWSvnetlHLEKERVSEEKqvaekryqQEHRDRESLVAEREkLLKEINAaqee 1153
Cdd:pfam12128  813 ATQLSNIERAISELQQQLARLIADTKLRRA-----KLEMERKASEK--------QQVRLSENLRGLRC-EMSKLAT---- 874

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1154 lLKMHMENDSLEASKVSMQVLIEELrfcKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVK 1233
Cdd:pfam12128  875 -LKEDANSEQAQGSIGERLAQLEDL---KLKRDYLSESVKKYVEHFKNVIADHSGSGLAETWESLREEDHYQNDKGIRLL 950

                          890
                   ....*....|..
gi 568937382  1234 DQKALVQEIEDL 1245
Cdd:pfam12128  951 DYRKLVPYLEQW 962
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-594 8.77e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 8.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRT 414
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLEsskppgd 494
Cdd:COG4913   700 ELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLE------- 772

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  495 vdmslsllQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSK-ENESL---RSKLDHANKENS 570
Cdd:COG4913   773 --------ERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRlEEDGLpeyEERFKELLNENS 844

                         250       260
                  ....*....|....*....|....*
gi 568937382  571 DV-IALWKSKLETAIASHQQAMEEL 594
Cdd:COG4913   845 IEfVADLLSKLRRAIREIKERIDPL 869
PTZ00121 PTZ00121
MAEBL; Provisional
 1567-2069 1.04e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1567 ECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQ--KVEE 1644
Cdd:PTZ00121 1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEakKAEE 1300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1645 IIKEKELlsAETAQLAANIETLKSDfAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMML 1724
Cdd:PTZ00121 1301 KKKADEA--KKKAEEAKKADEAKKK-AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1725 RNEEALKEKEKLEESYFILQKEISQLAQTNSHI---------SANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQ 1795
Cdd:PTZ00121 1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELkkaaaakkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1796 TAEDAMQIMEQM-----TKEKTETLASLEDTKQTNARLQNELDTLKE--------NNLKTVEELNKSKELLSVEN-QKME 1861
Cdd:PTZ00121 1458 KAEEAKKKAEEAkkadeAKKKAEEAKKADEAKKKAEEAKKKADEAKKaaeakkkaDEAKKAEEAKKADEAKKAEEaKKAD 1537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1862 EFKKEIETLKQAAAQKSQQLSalQEENVKLAEELGRT-RDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDA 1940
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKAEELK--KAEEKKKAEEAKKAeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1941 DEEKAslqKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 2020
Cdd:PTZ00121 1616 EEAKI---KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 568937382 2021 SgnTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAA 2069
Cdd:PTZ00121 1693 A--LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1718-1977 1.34e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1718 EKREMMLRNEEALKEKEKLEESYFILQKEISQLAQtnshisanLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1797
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIEL--------LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1798 EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveelnkskELLSVENQKMEEFKKEIETLKQAAAQK 1877
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEA-------------QIRGNGGDRLEQLEREIERLERELEER 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1878 SQQLSALQEenvkLAEELGrtrdevtshQKLEEERSVLNNQLLEMKkslpsntlresEFRKDADEEKASLQKSISLTSAL 1957
Cdd:COG4913   358 ERRRARLEA----LLAALG---------LPLPASAEEFAALRAEAA-----------ALLEALEEELEALEEALAEAEAA 413

                         250       260
                  ....*....|....*....|
gi 568937382 1958 LTEKDAELEKLRNEVTVLRG 1977
Cdd:COG4913   414 LRDLRRELRELEAEIASLER 433
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1111-1330 1.44e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1111 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckdklmamsE 1190
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR----------A 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1191 KARAEKEHLEGQVKKL----TAENLVLVKDKDDVIQKLQSA--YEELVKDQKalvQEIEDLTTEKKSAAEKQMSLDNTCL 1264
Cdd:COG4942    98 ELEAQKEELAELLRALyrlgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARR---EQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382 1265 TLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAE 1330
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 538-1217 1.63e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   538 QKEIKALHTATEKLSKENESLRSKLDHANKENSDVIA------LWKSKLETAIAS----------HQQAMEELKVSFSKG 601
Cdd:pfam05483  112 RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNN 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   602 IGTDSAEFAELKTQIERLRLDYQHEIeslqsKQDSERSAHAKEmetmqaKLMKIIKEKEDSLEAVKARLDSAEDQhlveM 681
Cdd:pfam05483  192 IEKMILAFEELRVQAENARLEMHFKL-----KEDHEKIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----M 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   682 EDTLNKLQEAEIKVKELEvlqAKYTEQSEVIGNFTSQLSAVKEKLLDLD-ALRKANSEGKleleTLRQQLEGAEKQIKNL 760
Cdd:pfam05483  257 KDLTFLLEESRDKANQLE---EKTKLQDENLKELIEKKDHLTKELEDIKmSLQRSMSTQK----ALEEDLQIATKTICQL 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   761 ETERNAESSKANsitKELQEKELVLTGLQDSLNqvnqvkeTLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ 840
Cdd:pfam05483  330 TEEKEAQMEELN---KAKAAHSFVVTEFEATTC-------SLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   841 FNVLSSELEKLRENLTDMEAKFKEKDDRE---DQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 917
Cdd:pfam05483  400 KNNKEVELEELKKILAEDEKLLDEKKQFEkiaEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   918 LTKANENASFLQKSIGEVTLKAEQSQQQAArKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEIL 997
Cdd:pfam05483  480 LEKEKLKNIELTAHCDKLLLENKELTQEAS-DMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFI 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   998 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSE-----KQLYAQE--A 1070
Cdd:pfam05483  559 QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKgsaenKQLNAYEikV 638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1071 NALKLEKGSLLSKLIEV----ETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKE 1146
Cdd:pfam05483  639 NKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDK 718

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382  1147 INAAQEELLKMHMENDSLEAS-KVSMQVlieELRFCKDKLMAMSEKARAEKEHLEgQVKKLTAENLVLVKDK 1217
Cdd:pfam05483  719 IIEERDSELGLYKNKEQEQSSaKAALEI---ELSNIKAELLSLKKQLEIEKEEKE-KLKMEAKENTAILKDK 786
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2094-2111 1.87e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.87e-04
                           10
                   ....*....|....*...
gi 568937382  2094 RLFCDICDCFDlHDTEDC 2111
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1611-1978 1.92e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 1.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1611 EEEIQRLRVCSEQLQTENFTLTQEKtnsEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKI 1690
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRRER---EKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1691 LDDLRLNHEVALTERAEVlqdnknllaEKREMMLRNEEALKEKEKLEESYfilqkeiSQLAQTNSHISANLLESQSENRT 1770
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEEL---------NKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1771 LRKDKSKLTLKIRELETLHsftaaqtaedamQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSK 1850
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELE------------REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1851 EllsvenqKMEEFKKEIETLKQaaaqksqQLSALQEENVKLAEELGRTRDEVTS----HQKLEEERSVLNNQLLEMKKSL 1926
Cdd:TIGR02169  392 E-------KLEKLKREINELKR-------ELDRLQEELQRLSEELADLNAAIAGieakINELEEEKEDKALEIKKQEWKL 457

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937382  1927 PSNtlreSEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 1978
Cdd:TIGR02169  458 EQL----AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1563-1969 2.00e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.43  E-value: 2.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1563 NLQEECQKlneEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKV 1642
Cdd:pfam07888   34 NRLEECLQ---ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1643 EEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQelhscltkilddlrlnhevalTERAEVLQDNKNLLAEKREm 1722
Cdd:pfam07888  111 EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERE---------------------TELERMKERAKKAGAQRKE- 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1723 mlrnEEAlkEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKireLETLHSFTAAqtaedamq 1802
Cdd:pfam07888  169 ----EEA--ERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQK---LTTAHRKEAE-------- 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1803 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSK-ELLSVENQKMEEFKKeietLKQAAAQKSQQL 1881
Cdd:pfam07888  232 -NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARlQAAQLTLQLADASLA----LREGRARWAQER 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1882 SALQEENVKLAEELGRTRDEVTSHQK-LEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKSISLTSALLTE 1960
Cdd:pfam07888  307 ETLQQSAEADKDRIEKLSAELQRLEErLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386


                   ....*....
gi 568937382  1961 KDAELEKLR 1969
Cdd:pfam07888  387 KQELLEYIR 395
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1727-1910 2.16e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1727 EEALKEKEKLEESYFILQKEISQLAQtnshisanllesqsENRTLRKDKSKLTLKIRELETLHsftAAQTAEDAMQIMEQ 1806
Cdd:COG4717    77 EEELKEAEEKEEEYAELQEELEELEE--------------ELEELEAELEELREELEKLEKLL---QLLPLYQELEALEA 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1807 MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQK-MEEFKKEIETLKQAAAQKSQQLSALQ 1885
Cdd:COG4717   140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQ 219

                         170       180
                  ....*....|....*....|....*
gi 568937382 1886 EENVKLAEELGRTRDEVTSHQKLEE 1910
Cdd:COG4717   220 EELEELEEELEQLENELEAAALEER 244
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1084-2038 2.84e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1084 LIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDS 1163
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1164 LEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQsayeelvKDQKALVQEIE 1243
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLL----EDQNSKLS-------KERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1244 DLTTEKKSAAEKQMSLDNtcltlkaerenllqtnrdlqfekdtLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCAS 1323
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSK-------------------------LKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGES 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1324 KALRKAELDMR-QLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSEnRIITEKLSKQ--- 1399
Cdd:pfam01576  218 TDLQEQIAELQaQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQrrd 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1400 -SEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLladRESSIKTIGDLRRKYDQEATNRR 1478
Cdd:pfam01576  297 lGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEM---RQKHTQALEELTEQLEQAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1479 IVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLL 1558
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAE 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1559 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTenftLTQEKTNS 1638
Cdd:pfam01576  454 GKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLST----LQAQLSDM 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1639 EQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDL--RLNHEVALTERAEVLQDN-KNL 1715
Cdd:pfam01576  530 KKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvDLDHQRQLVSNLEKKQKKfDQM 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1716 LAEKREMMLRN-------------------------EEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRT 1770
Cdd:pfam01576  610 LAEEKAISARYaeerdraeaeareketralslaralEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1771 LRKDKSKLTLKIRELETlhSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQ-----NELDTLKENNLKTVEE 1845
Cdd:pfam01576  690 LEQQVEEMKTQLEELED--ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQlvkqvRELEAELEDERKQRAQ 767

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1846 LNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERS-VLNNQLLEMKK 1924
Cdd:pfam01576  768 AVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLkNLEAELLQLQE 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1925 SLPSNTLRESEFRKDADEEKASLQKSISLTSALLTEK-------------------DAELEKLRNEVTVLRGENATAK-- 1983
Cdd:pfam01576  848 DLAASERARRQAQQERDELADEIASGASGKSALQDEKrrleariaqleeeleeeqsNTELLNDRLRKSTLQVEQLTTEla 927

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568937382  1984 SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQ 2038
Cdd:pfam01576  928 AERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQ 982
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1221-1684 3.08e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 3.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1221 IQKLQSAYEELVKDQ----KALVQEIEDLTTEKKSAAEKQmsldntcltlkAERENLLQTNRDLQFEKDTLRQGQEKLSA 1296
Cdd:COG4717    48 LERLEKEADELFKPQgrkpELNLKELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELRE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1297 SLEATLQVKQLLST--EAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKEslaAS 1374
Cdd:COG4717   117 ELEKLEKLLQLLPLyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EE 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1375 ERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEVAcQKVAKLKKQQDSLLKEKSALELQ-NGDLL 1453
Cdd:COG4717   194 LQDLAEELEELQQRLAELEEELEEAQEELEELE----EELEQLENELEAA-ALEERLKEARLLLLIAAALLALLgLGGSL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1454 ADRESSIKTIGDL-------------RRKYDQEATNRRIVMQEKMKLLGNIDaLKKELQERKKENQELTSSKCDLSLLLK 1520
Cdd:COG4717   269 LSLILTIAGVLFLvlgllallflllaREKASLGKEAEELQALPALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIE 347

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1521 EAQDAKKNLEKEHTSM--IQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLY 1598
Cdd:COG4717   348 ELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE 427

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1599 ENnkLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTN--SEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKS 1676
Cdd:COG4717   428 EE--LEEELEELEEELEELEEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAEEWAALKLALELLEEA 505


                  ....*...
gi 568937382 1677 KLELQELH 1684
Cdd:COG4717   506 REEYREER 513
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1556-1986 3.47e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 3.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1556 MLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEK 1635
Cdd:COG4717    46 MLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1636 TNSE--QKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL----TERAEVL 1709
Cdd:COG4717   126 QLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELqdlaEELEELQ 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1710 QDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQ-----KEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRE 1784
Cdd:COG4717   206 QRLAELEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1785 LETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEdtkqtnarLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFK 1864
Cdd:COG4717   286 LALLFLLLAREKASLGKEAEELQALPALEELEEEE--------LEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1865 KEIETLKQAAAQKSQQlSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLpsNTLRESEFRKDADEEK 1944
Cdd:COG4717   358 ELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL--EELLEALDEEELEEEL 434

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568937382 1945 ASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLH 1986
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1314-2024 3.60e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 3.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1314 TLRTQLDCASKALRKAeldmRQLQTSNSSLTKLLEEIKTCRAItdseciqllHEKESLAASE-----RTLLAEKEELlsE 1388
Cdd:COG5022   759 YLRRRYLQALKRIKKI----QVIQHGFRLRRLVDYELKWRLFI---------KLQPLLSLLGsrkeyRSYLACIIKL--Q 823

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1389 NRIITEKLSKQSEEVARLEMGLNEKITYLTSEKevacqkvakLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRR 1468
Cdd:COG5022   824 KTIKREKKLRETEEVEFSLKAEVLIQKFGRSLK---------AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSI 894

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1469 KY--------DQEAT----NRRIVMQEKMKLLGNIDA-LKKELQERKKENQ---ELTSSKCDLSLL-----LKEAQDAKK 1527
Cdd:COG5022   895 SSlklvnlelESEIIelkkSLSSDLIENLEFKTELIArLKKLLNNIDLEEGpsiEYVKLPELNKLHeveskLKETSEEYE 974

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1528 NLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlILEKEARAKESETSLYENNKLHGRV 1607
Cdd:COG5022   975 DLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAE--LQSASKIISSESTELSILKPLQKLK 1052

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1608 VLLEEEIQRLRVCSEQLQTEN--------FTLTQEKTNSEQKVeeiIKEKELLSAETaQLAANIETLKSDFAALSKSKLE 1679
Cdd:COG5022  1053 GLLLLENNQLQARYKALKLRRensllddkQLYQLESTENLLKT---INVKDLEVTNR-NLVKPANVLQFIVAQMIKLNLL 1128

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1680 LQELHSCLTKILDdlrlnhevalteraevLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAqtNSHISA 1759
Cdd:COG5022  1129 QEISKFLSQLVNT----------------LEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQ--SALYDE 1190

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1760 NLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEdAMQIMEQMTKEKTETLASLEDTKQTNarlqneldtlkENN 1839
Cdd:COG5022  1191 KSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISE-GWVPTEYSTSLKGFNNLNKKFDTPAS-----------MSN 1258

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1840 LKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENV--KLAEELGRTRDEVtSHQKLEEERSVLNN 1917
Cdd:COG5022  1259 EKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLrwKSATEVNYNSEEL-DDWCREFEISDVDE 1337

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1918 QLLEMKKSLPSNTLRESEfrkdadeekasLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKslhSVVQTLESDKV 1997
Cdd:COG5022  1338 ELEELIQAVKVLQLLKDD-----------LNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLPK---EILKKIEALLI 1403

                         730       740
                  ....*....|....*....|....*..
gi 568937382 1998 KLELKVKNLELQLKENKRQLSSSSGNT 2024
Cdd:COG5022  1404 KQELQLSLEGKDETEVHLSEIFSEEKS 1430
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1573-2007 4.08e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 4.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1573 EEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELL 1652
Cdd:PRK02224  289 EELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAEL 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1653 SAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEA--L 1730
Cdd:PRK02224  369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAeaL 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1731 KEKEKLEESYFILqkEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTA--------AQTAEDAMQ 1802
Cdd:PRK02224  449 LEAGKCPECGQPV--EGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDrierleerREDLEELIA 526

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1803 IMEQMTKEKTETLASLEDTKQtnaRLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQ------AAAQ 1876
Cdd:PRK02224  527 ERRETIEEKRERAEELRERAA---ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtllaAIAD 603

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1877 KSQQLSALQEENVKLAEELGRTRDEVTS----HQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDA-DEEKASLQKSI 1951
Cdd:PRK02224  604 AEDEIERLREKREALAELNDERRERLAEkrerKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDElREERDDLQAEI 683

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382 1952 sltsALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLES--DKVKLELKVKNLE 2007
Cdd:PRK02224  684 ----GAVENELEELEELRERREALENRVEALEALYDEAEELESmyGDLRAELRQRNVE 737
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
869-1306 4.15e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  869 EDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGE----VTLKAEQSQQ 944
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEElreeLEKLEKLLQL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  945 QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQD 1024
Cdd:COG4717   128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1025 MEELKTQADKAKSltyLLTSAKKEIEVMSEELRGLKSEKQLYAQEAN--------ALKLEKGSLLSKLIEVETKITLLQE 1096
Cdd:COG4717   208 LAELEEELEEAQE---ELEELEEELEQLENELEAAALEERLKEARLLlliaaallALLGLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1097 DQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSM--QVL 1174
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1175 IEELRFCKDKLMAMS------------------EKARAEKEHLEGQVKKLTAENLVLVKDKDDviQKLQSAYEELVKDQK 1236
Cdd:COG4717   365 LEELEQEIAALLAEAgvedeeelraaleqaeeyQELKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELE 442

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382 1237 ALVQEIEDLTTEKKSAAE--KQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQ 1306
Cdd:COG4717   443 ELEEELEELREELAELEAelEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 607-909 4.65e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 4.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  607 AEFAELKTQIErlrlDYQHEIESLQSKQDSERSA-HAKEMETMQAKLMKI-IKEKEDSLEAVKARLDSAeDQHLVEMEDT 684
Cdd:COG3096   389 EEVDSLKSQLA----DYQQALDVQQTRAIQYQQAvQALEKARALCGLPDLtPENAEDYLAAFRAKEQQA-TEEVLELEQK 463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  685 LNKLQEAEI---KVKELEVLQAKYTEQSEVIGNFTSQLSAVKEklLDLDALRKANSEGKL-ELETLRQQLEGAEKQIKNL 760
Cdd:COG3096   464 LSVADAARRqfeKAYELVCKIAGEVERSQAWQTARELLRRYRS--QQALAQRLQQLRAQLaELEQRLRQQQNAERLLEEF 541

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  761 ETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEA---VSAQTRMQDTVNKLHQK 837
Cdd:COG3096   542 CQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARApawLAAQDALERLREQSGEA 621

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937382  838 EEQFNVLSSELEKLRENLTDMEAKfkekddrEDQLVKAKEKLENDIAEIMKMSGDNSSQLtkmndeLRLKER 909
Cdd:COG3096   622 LADSQEVTAAMQQLLEREREATVE-------RDELAARKQALESQIERLSQPGGAEDPRL------LALAER 680
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 991-1523 5.06e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.48  E-value: 5.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   991 TKHEEILQNLQKMLADTEDKLKAAQEANRdlMQDmEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEA 1070
Cdd:pfam05483  250 TEKENKMKDLTFLLEESRDKANQLEEKTK--LQD-ENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTI 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1071 NALKLEKGSLLSKLIEVETKITLL-QEDQQKLWSVNETLHLEKERVsEEKQVAEKRYQQEHRDRESLVAEREKLLKEINA 1149
Cdd:pfam05483  327 CQLTEEKEAQMEELNKAKAAHSFVvTEFEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEV 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1150 AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQ---- 1225
Cdd:pfam05483  406 ELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEkekl 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1226 ------SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLE 1299
Cdd:pfam05483  486 knieltAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVK 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1300 ATLQVKQLLSTEAETLRTQLDCASKALRKAELDMR-QLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTL 1378
Cdd:pfam05483  566 CKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKkQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELEL 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1379 LAEKEELLSenriITEKLSKQSEEVARLEMGLNEKItyltSEKEVACQKVAKLKKQQDSLLKEKSALEL--------QNG 1450
Cdd:pfam05483  646 ASAKQKFEE----IIDNYQKEIEDKKISEEKLLEEV----EKAKAIADEAVKLQKEIDKRCQHKIAEMValmekhkhQYD 717

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937382  1451 DLLADRESSIktigDLRRKYDQEATNRRIVMQEKMKLLGN-IDALKKELQERKKENQELTSSKCDLSLLLKEAQ 1523
Cdd:pfam05483  718 KIIEERDSEL----GLYKNKEQEQSSAKAALEIELSNIKAeLLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1820-2096 6.28e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.07  E-value: 6.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1820 DTKQTNARLQNELDTLKENNLKTVEELNKSKELLSvenqkmEEFKKEIETLKQAAAQKSQQLSALQEENVKLAE-ELGRT 1898
Cdd:COG5022   814 SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLI------QKFGRSLKAKKRFSLLKKETIYLQSAQRVELAErQLQEL 887

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1899 RDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKSISLTSALLTE--KDAELEKLRNEVTVLR 1976
Cdd:COG5022   888 KIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEyvKLPELNKLHEVESKLK 967

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1977 GENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQ 2056
Cdd:COG5022   968 ETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKP 1047

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 568937382 2057 DLKMKVEMMSEA-ALNGNGEDL-----NSYDSDDQEKQSKKKPRLF 2096
Cdd:COG5022  1048 LQKLKGLLLLENnQLQARYKALklrreNSLLDDKQLYQLESTENLL 1093
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
800-918 6.47e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 6.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  800 ETLEKELQTLKEKfaSTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDR----EDQLVKA 875
Cdd:COG2433   376 LSIEEALEELIEK--ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERierlERELSEA 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568937382  876 KEKLENDI---AEIMKMSGDNsSQLTKmndELRLKERSVEELQLKL 918
Cdd:COG2433   454 RSEERREIrkdREISRLDREI-ERLER---ELEEERERIEELKRKL 495
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1703-2063 6.60e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1703 TERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKI 1782
Cdd:PRK02224  213 SELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1783 RELETLHSFTAAQT------AEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVE------------ 1844
Cdd:PRK02224  289 EELEEERDDLLAEAglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEEraeelreeaael 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1845 --ELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQ-KLEEERSVL--NNQL 1919
Cdd:PRK02224  369 esELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVeeAEAL 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1920 LEMKKSLPSNTLRESEFRKDADEEKaslqksisltSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL 1999
Cdd:PRK02224  449 LEAGKCPECGQPVEGSPHVETIEED----------RERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERR 518

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937382 2000 ELKVKNLELQ---LKENKRQLSSS---SGNTDAQAEE-DERAQESQQMIDFLNSVIVDLQRKNQDLKMKVE 2063
Cdd:PRK02224  519 EDLEELIAERretIEEKRERAEELrerAAELEAEAEEkREAAAEAEEEAEEAREEVAELNSKLAELKERIE 589
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1564-1763 7.35e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 7.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1564 LQEECQKLNEEIREIQQTLILEKEARAKESETslyennklhgRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVE 1643
Cdd:COG4913   257 IRELAERYAAARERLAELEYLRAALRLWFAQR----------RLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1644 EIikEKELLSAETAQlaanIETLKSDFAALSKSKLELQELHSCLTKILDDLRL---NHEVALTERAEVLQDNKNLLAEKR 1720
Cdd:COG4913   327 EL--EAQIRGNGGDR----LEQLEREIERLERELEERERRRARLEALLAALGLplpASAEEFAALRAEAAALLEALEEEL 400

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 568937382 1721 EmMLRNE--EALKEKEKLEESYFILQKEISQLAQTNSHISANLLE 1763
Cdd:COG4913   401 E-ALEEAlaEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA 444
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1110-1320 7.86e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 7.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1110 LEKERVSEEKQVAEKRYQQEHRDRESLVAEREK--LLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFckDKLMA 1187
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQieLLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL--ELLEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1188 MSEKARAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKA-LVQEIEDLTTEKKSAAEKQMSLDNTC--- 1263
Cdd:COG4913   296 ELEELRAELARLEAELERLEAR----LDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARLEALLaal 371

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382 1264 -LTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLD 1320
Cdd:COG4913   372 gLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA 429
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1096-1408 1.10e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1096 EDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEEllkmhmendsleaskvsmqVLI 1175
Cdd:PLN02939  114 EQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGK-------------------INI 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1176 EELRFCK-DKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAE 1254
Cdd:PLN02939  175 LEMRLSEtDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAE 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1255 KqmslDNTCLTLKAERENLLQTNRDLQFekdTLRQGQEKLSASleATLQVKQLLStEAETLRTQLDCASKALRKAELDMR 1334
Cdd:PLN02939  255 T----EERVFKLEKERSLLDASLRELES---KFIVAQEDVSKL--SPLQYDCWWE-KVENLQDLLDRATNQVEKAALVLD 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1335 QLQTSNSSLTKL---LEEIKTCRaiTDSECIQLLHEKesLAASERTLLAEKEELLSENRI-------ITEKLSKQSEEVA 1404
Cdd:PLN02939  325 QNQDLRDKVDKLeasLKEANVSK--FSSYKVELLQQK--LKLLEERLQASDHEIHSYIQLyqesikeFQDTLSKLKEESK 400


                  ....
gi 568937382 1405 RLEM 1408
Cdd:PLN02939  401 KRSL 404
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
770-1129 1.15e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  770 KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELE 849
Cdd:COG4372    11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  850 KLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQ 929
Cdd:COG4372    91 AAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  930 KSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTED 1009
Cdd:COG4372   171 QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1010 KLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVET 1089
Cdd:COG4372   251 LLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLEL 330

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 568937382 1090 KITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQE 1129
Cdd:COG4372   331 ALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
COG5022 COG5022
Myosin heavy chain [General function prediction only];
748-1113 1.21e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  748 QQLEGAEKQIKNLETErNAESSKANSITKELQEKELVLT-GLQDSLNQVNQVKETLEKELQTLKEKfaSTSEEAVSAQTR 826
Cdd:COG5022   875 QRVELAERQLQELKID-VKSISSLKLVNLELESEIIELKkSLSSDLIENLEFKTELIARLKKLLNN--IDLEEGPSIEYV 951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  827 MQDTVNKLHQKEeqfnvlsSELEKLRENLTDMeakFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSqLTKMNDELRL 906
Cdd:COG5022   952 KLPELNKLHEVE-------SKLKETSEEYEDL---LKKSTILVREGNKANSELKNFKKELAELSKQYGA-LQESTKQLKE 1020

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  907 KERSVEELQLKLTKANENASFL------QKSIGEVTLKAEQSQQQAarKHEEEKKELEEKLLELEKKMETSYNQCQDLKA 980
Cdd:COG5022  1021 LPVEVAELQSASKIISSESTELsilkplQKLKGLLLLENNQLQARY--KALKLRRENSLLDDKQLYQLESTENLLKTINV 1098

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  981 KYEKASSETKTKHEEILQNLQKMLADTeDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLK 1060
Cdd:COG5022  1099 KDLEVTNRNLVKPANVLQFIVAQMIKL-NLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAAL 1177

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568937382 1061 SEKQLYaqEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVN-ETLHLEKE 1113
Cdd:COG5022  1178 SEKRLY--QSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGdKLKKLISE 1229
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
978-1447 1.23e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  978 LKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKaksltylLTSAKKEIEVMSEELR 1057
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEE-------LEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1058 GLKSEKQLYA--QEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQ----VAEKRYQQEHR 1131
Cdd:COG4717   120 KLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAE 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1132 DRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQvLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENL 1211
Cdd:COG4717   200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA-LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1212 VLVkdkddVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQ 1291
Cdd:COG4717   279 LFL-----VLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1292 EKLsASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQtsnssltKLLEEIKTCRAITDSECIQLLHEKEsl 1371
Cdd:COG4717   354 REA-EELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQ-------ELKEELEELEEQLEELLGELEELLE-- 423

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382 1372 AASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEV--ACQKVAKLKKQQDSLLKEKSALEL 1447
Cdd:COG4717   424 ALDEEELEEELEELEEELEELEEELEELREELAELE----AELEQLEEDGELaeLLQELEELKAELRELAEEWAALKL 497
PRK01156 PRK01156
chromosome segregation protein; Provisional
 697-1273 1.32e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  697 ELEVLQAKYTEQSEVIGNFTSQLSavkekllDLDALRKANSEGKLELETLRQQLEGAE-------KQIKNLETERNAESS 769
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEIS-------NIDYLEEKLKSSNLELENIKKQIADDEkshsitlKEIERLSIEYNNAMD 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  770 KANSITKELQEkelvLTGLQDSLNQVNQVKETLEKELQTLKEKFAS-----------TSEEAVSAQTRMQDTVNKLHQKE 838
Cdd:PRK01156  233 DYNNLKSALNE----LSSLEDMKNRYESEIKTAESDLSMELEKNNYykeleerhmkiINDPVYKNRNYINDYFKYKNDIE 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  839 EQFNVLS---SELEKLREN---LTDMEA---KFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKER 909
Cdd:PRK01156  309 NKKQILSnidAEINKYHAIikkLSVLQKdynDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIER 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  910 SVEELQLKLTKANENASFLQKSIGEVTLKAEQ-SQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSE 988
Cdd:PRK01156  389 MSAFISEILKIQEIDPDAIKKELNEINVKLQDiSSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSN 468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  989 TKTKH-EEILQNLQKMLADTEDKLKAAQEANRDLMQdMEELKTQADKAKSLTY--LLTSAKKEIEVMSEELRGLKSEKQL 1065
Cdd:PRK01156  469 HIINHyNEKKSRLEEKIREIEIEVKDIDEKIVDLKK-RKEYLESEEINKSINEynKIESARADLEDIKIKINELKDKHDK 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1066 YaqeaNALKLEKGSLlsKLIEVETKITLLQEDQQKLWSVN-ETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLL 1144
Cdd:PRK01156  548 Y----EEIKNRYKSL--KLEDLDSKRTSWLNALAVISLIDiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSI 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1145 KEInaaQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEhLEGQVKKLTaENLVLVKDKDDVIQKL 1224
Cdd:PRK01156  622 REI---ENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKE-ITSRINDIE-DNLKKSRKALDDAKAN 696

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 568937382 1225 QSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1273
Cdd:PRK01156  697 RARLESTIEILRTRINELSDRINDINETLESMKKIKKAIGDLKRLREAF 745
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1632-1894 1.45e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1632 TQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHScltkilddlrlnhevALTERAEVLQD 1711
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR---------------ALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1712 NKNLLAEKREMMLRNEEALKEKekleesyfiLQKEISQLAQTNSHISANLLESQSENRTLrkdkskltlkIRELETLHSF 1791
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEE---------LAELLRALYRLGRQPPLALLLSPEDFLDA----------VRRLQYLKYL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1792 TAAQtaedaMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLK 1871
Cdd:COG4942   145 APAR-----REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219

                         250       260
                  ....*....|....*....|...
gi 568937382 1872 QAAAQKSQQLSALQEENVKLAEE 1894
Cdd:COG4942   220 QEAEELEALIARLEAEAAAAAER 242
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
720-1050 1.52e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  720 SAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVK 799
Cdd:COG4372    31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  800 ETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREdqLVKAKEKL 879
Cdd:COG4372   111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE--AEQALDEL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  880 ENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 959
Cdd:COG4372   189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  960 KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLT 1039
Cdd:COG4372   269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348

                         330
                  ....*....|.
gi 568937382 1040 YLLTSAKKEIE 1050
Cdd:COG4372   349 GLLDNDVLELL 359
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1119-1412 1.52e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1119 KQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEH 1198
Cdd:pfam07888   54 NRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRE 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1199 LEGQVKKLTAENLvlvkDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLdntCLTLKAERENLLQTNR 1278
Cdd:pfam07888  134 LEEDIKTLTQRVL----ERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSL---SKEFQELRNSLAQRDT 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1279 DLQFEKDTLRQGQEKLSASLEATLQVKQLLsteaETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITD 1358
Cdd:pfam07888  207 QVLQLQDTITTLTQKLTTAHRKEAENEALL----EELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAA 282

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568937382  1359 SECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNE 1412
Cdd:pfam07888  283 QLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQE 336
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 644-816 1.82e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  644 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNftsqlsaVK 723
Cdd:COG1579    21 RLEHRLKELPAELAELEDELAALEARLEAAKTEL----EDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-------NK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  724 EklldLDALRKansegklELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLE 803
Cdd:COG1579    90 E----YEALQK-------EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAEL 158

                         170
                  ....*....|...
gi 568937382  804 KELQTLKEKFAST 816
Cdd:COG1579   159 EELEAEREELAAK 171
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 1804-1986 2.00e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 42.44  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1804 MEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNkskellsvenQKMEEFKKEIETLKQAAAQKSQQLSA 1883
Cdd:pfam09787   49 LEELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEEAESSR----------EQLQELEEQLATERSARREAEAELER 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1884 LQEENVKLAEELGRTRDE-VTSHQKLEEERSVLNNQLleMKKSLPSNTLRESEFRKDADEEkaSLQKSISLTSALLTEKD 1962
Cdd:pfam09787  119 LQEELRYLEEELRRSKATlQSRIKDREAEIEKLRNQL--TSKSQSSSSQSELENRLHQLTE--TLIQKQTMLEALSTEKN 194

                          170       180
                   ....*....|....*....|....*..
gi 568937382  1963 A---ELEKLRNEVTVLRGENATAKSLH 1986
Cdd:pfam09787  195 SlvlQLERMEQQIKELQGEGSNGTSIN 221
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1787-2021 2.20e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1787 TLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveELNKSKELLSVENQKMEEFKKE 1866
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-------RIAALARRIRALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1867 IETLKQAAAQKSQQLSALQEENVKLAEELGRTRDE------VTSHQKLEEERSV-----LNNQLLEMKKSLPSNTLRESE 1935
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAELLRALYRLGRQpplallLSPEDFLDAVRRLqylkyLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1936 FRKDADEEKASLQKSIsltsALLTEKDAELEKLRNEV-TVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENK 2014
Cdd:COG4942   165 LRAELEAERAELEALL----AELEEERAALEALKAERqKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                  ....*..
gi 568937382 2015 RQLSSSS 2021
Cdd:COG4942   241 ERTPAAG 247
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 638-883 2.20e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 43.09  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   638 RSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTS 717
Cdd:pfam05667  231 LASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGLTKGSRFTHTEKLQFTN 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   718 QLSAVKEKLL----DLDALRKANSEgklELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLN 793
Cdd:pfam05667  311 EAPAATSSPPtkveTEEELQQQREE---ELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   794 ------------QVNQVKetLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ----KEEQFNVLSSELEKLRENLTD 857
Cdd:pfam05667  388 vkkktldllpdaEENIAK--LQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEaksnKEDESQRKLEEIKELREKIKE 465

                          250       260
                   ....*....|....*....|....*.
gi 568937382   858 MEAKFKEKDDREDQLVKAKEKLENDI 883
Cdd:pfam05667  466 VAEEAKQKEELYKQLVAEYERLPKDV 491
mukB PRK04863
chromosome partition protein MukB;
817-1208 2.22e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  817 SEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREdQLVKA----KEKLENDIAEIMKMsgd 892
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTalrqQEKIERYQADLEEL--- 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  893 nSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVtlkaeqsqQQAarkheeekkeleekllelEKKMETSY 972
Cdd:PRK04863  361 -EERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADY--------QQA------------------LDVQQTRA 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  973 NQCQDLKAKYEKASSETKTKHEEiLQNLQKMLADTEDKLKAAQEANRDLMQDM---EELKTQADKAKSltyLLTSAKKEI 1049
Cdd:PRK04863  414 IQYQQAVQALERAKQLCGLPDLT-ADNAEDWLEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQ---LVRKIAGEV 489

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1050 E------VMSEELRGLKSEKQLyAQEANALKLEKGSLLSKLIEVETKITLLQEDQQK----------LWSVNETLHLEKE 1113
Cdd:PRK04863  490 SrseawdVARELLRRLREQRHL-AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRlgknlddedeLEQLQEELEARLE 568

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1114 RVSEEKQVAEKRYQQEHRDRESLVAEREKLLK---EINAAQEEL--LKMHMENDSLEASKVS--MQVLIEELRfckdKLM 1186
Cdd:PRK04863  569 SLSESVSEARERRMALRQQLEQLQARIQRLAArapAWLAAQDALarLREQSGEEFEDSQDVTeyMQQLLERER----ELT 644

                         410       420
                  ....*....|....*....|..
gi 568937382 1187 AMSEKARAEKEHLEGQVKKLTA 1208
Cdd:PRK04863  645 VERDELAARKQALDEEIERLSQ 666
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1124-1580 2.45e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1124 KRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSE--KARAEKEHLEG 1201
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1202 QVKKLtaenlvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSldntclTLKAERENLLQTNRDLQ 1281
Cdd:COG4717   147 RLEEL--------EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ------DLAEELEELQQRLAELE 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1282 FEKDTLRQGQEKLSASLEAtLQVKQLLSTEAETLRTQldcasKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSEC 1361
Cdd:COG4717   213 EELEEAQEELEELEEELEQ-LENELEAAALEERLKEA-----RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1362 IQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKE 1441
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1442 KSALELQNgdLLAdrESSIKTIGDLRRKYDQEatnrrivmQEKMKLLGNIDALKKELQERKKENQEL--TSSKCDLSLLL 1519
Cdd:COG4717   367 ELEQEIAA--LLA--EAGVEDEEELRAALEQA--------EEYQELKEELEELEEQLEELLGELEELleALDEEELEEEL 434

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937382 1520 KEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmLLRDGL--NLQEECQKLNEEIREIQQ 1580
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQ-------LEEDGElaELLQELEELKAELRELAE 490
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 740-909 2.94e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  740 KLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKelvltgLQDSLNQvnqvketLEKELQTLKEKFastsEE 819
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAE------LRDELAE-------LEEELEALKARW----EA 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  820 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDredqlvkakeklENDIAEIM---------KMS 890
Cdd:COG0542   466 EKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVT------------EEDIAEVVsrwtgipvgKLL 533

                         170
                  ....*....|....*....
gi 568937382  891 GDNSSQLTKMNDElrLKER 909
Cdd:COG0542   534 EGEREKLLNLEEE--LHER 550
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1426-1675 3.05e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1426 QKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKEn 1505
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1506 qeltsskcdLSLLLKEAQdakKNLEKEHTSMIQAKDNLNAelktccceknmLLRDGLNLQEECQKLNEEIREIQQTLile 1585
Cdd:COG4942   106 ---------LAELLRALY---RLGRQPPLALLLSPEDFLD-----------AVRRLQYLKYLAPARREQAEELRADL--- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1586 kearakesetslyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIET 1665
Cdd:COG4942   160 ---------------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224

                         250
                  ....*....|
gi 568937382 1666 LKSDFAALSK 1675
Cdd:COG4942   225 LEALIARLEA 234
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 623-2006 3.11e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.12  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   623 YQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKvkelevlq 702
Cdd:TIGR01612  472 FEEEWGSYDIKKDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKAKLYKEIE-------- 543

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   703 akyteqsevignftsqlSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNL---ETERNAESSKANSITKELQ 779
Cdd:TIGR01612  544 -----------------AGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLfdkYLEIDDEIIYINKLKLELK 606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   780 EKELVLTGLQDSLNQVNQVKETLEKELQTLKEkFASTSEEAVSAQTRMQDTVnklhqkeeqFNVLSSELEKLRENltDME 859
Cdd:TIGR01612  607 EKIKNISDKNEYIKKAIDLKKIIENNNAYIDE-LAKISPYQVPEHLKNKDKI---------YSTIKSELSKIYED--DID 674

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   860 AKFKE-----KDDREDQlVKAKEKLEndiaeimkmsgDNSSQLTKMNDELRLKERSVEELQLKLTKANENasflqkSIGE 934
Cdd:TIGR01612  675 ALYNElssivKENAIDN-TEDKAKLD-----------DLKSKIDKEYDKIQNMETATVELHLSNIENKKN------ELLD 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   935 VTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHeeilqNLQKMLADTEDklkaa 1014
Cdd:TIGR01612  737 IIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHY-----NDQINIDNIKD----- 806

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1015 qeanrdlmqdmEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLK----SEKQLYAQEANALKLEKGSLLSKLIEVETK 1090
Cdd:TIGR01612  807 -----------EDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKddflNKVDKFINFENNCKEKIDSEHEQFAELTNK 875

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1091 ITLLQEDQQkLWSVNETLHLEKERVSEEKQVAEKRYQQEHRdreslVAEREKLLKEINAAQEELLKMHMENDSLEA---- 1166
Cdd:TIGR01612  876 IKAEISDDK-LNDYEKKFNDSKSLINEINKSIEEEYQNINT-----LKKVDEYIKICENTKESIEKFHNKQNILKEilnk 949

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1167 --SKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKL-----QSAYEELVKDQKALV 1239
Cdd:TIGR01612  950 niDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNNELIKYFNDLKANLgknkeNMLYHQFDEKEKATN 1029

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1240 QEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLqFEKDTLRQGQEKLSASLEATLQVKqlLSTEAETLRTQL 1319
Cdd:TIGR01612 1030 DIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIEL-LNKEILEEAEINITNFNEIKEKLK--HYNFDDFGKEEN 1106

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1320 DCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAasERTLLAEK-EELLSENRIITEKLSK 1398
Cdd:TIGR01612 1107 IKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVA--DKAISNDDpEEIEKKIENIVTKIDK 1184

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1399 QSEevarlemgLNEKITYLTSEkevacqkVAKLKKQQDSLLKEKSaLELQNGdlladressiKTIGDL-RRKYDQEATNR 1477
Cdd:TIGR01612 1185 KKN--------IYDEIKKLLNE-------IAEIEKDKTSLEEVKG-INLSYG----------KNLGKLfLEKIDEEKKKS 1238

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1478 RIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLlkeaqDAKKNLEKEHTSMIQAKDNLNAELKtcccEKNML 1557
Cdd:TIGR01612 1239 EHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETF-----NISHDDDKDHHIISKKHDENISDIR----EKSLK 1309

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1558 LRDGLNlqeECQKLNEEIREIQQTLIlekEARAKESETSLYENNKLHGRVVL----LEEEIQRLRVCSEQLQTENFTLTQ 1633
Cdd:TIGR01612 1310 IIEDFS---EESDINDIKKELQKNLL---DAQKHNSDINLYLNEIANIYNILklnkIKKIIDEVKEYTKEIEENNKNIKD 1383

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1634 EKTNSEQKVEEIIKEkellsaetaqlaANIETLKSDFaalsKSKLELQELHSCLTKILDdlrlnhevaltERAEVLQDNK 1713
Cdd:TIGR01612 1384 ELDKSEKLIKKIKDD------------INLEECKSKI----ESTLDDKDIDECIKKIKE-----------LKNHILSEES 1436

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1714 NllaekremmlrNEEALKEKEKLEESYFILQKEISQLAQTNSHIsanlLESQSENRTLRKDKSKLTLKIRELETLHSFTA 1793
Cdd:TIGR01612 1437 N-----------IDTYFKNADENNENVLLLFKNIEMADNKSQHI----LKIKKDNATNDHDFNINELKEHIDKSKGCKDE 1501

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1794 A----QTAEDAMQIMEQMTKEKTETLasledTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVE----NQKMEEFKK 1865
Cdd:TIGR01612 1502 AdknaKAIEKNKELFEQYKKDVTELL-----NKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEaeksEQKIKEIKK 1576

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1866 EIETLKQAAAQKSQ--------QLSALQEEN--VKLAEELGRTRDEVTSHQKLEEERSVL--NNQLLEMKKSLPS-NTLR 1932
Cdd:TIGR01612 1577 EKFRIEDDAAKNDKsnkaaidiQLSLENFENkfLKISDIKKKINDCLKETESIEKKISSFsiDSQDTELKENGDNlNSLQ 1656

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1933 esEFRKDADEEKaslqKSISLTSALLTEKDAELEKLRN---------EVTVLRGENATAKSLHsvvQTLESDKVKLELKV 2003
Cdd:TIGR01612 1657 --EFLESLKDQK----KNIEDKKKELDELDSEIEKIEIdvdqhkknyEIGIIEKIKEIAIANK---EEIESIKELIEPTI 1727


                   ...
gi 568937382  2004 KNL 2006
Cdd:TIGR01612 1728 ENL 1730
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1363-2092 3.47e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1363 QLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEvacqKVAKLKKQQDSLLKEK 1442
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDN----EIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1443 SALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKmkllgnIDALKKELQERKKENQELTSSKCDLSLLLK-- 1520
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRE------LEKLNKERRLLNQEKTELLVEQGRLQLQADrh 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1521 EAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYEN 1600
Cdd:TIGR00606  360 QEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLG 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1601 NKLHGRVVLLEEEIQRLRVCSEQLQTenftLTQEKTNSEQKVEEIIKEKELLSaeTAQLAANIETLKSDFAALSKSKLEL 1680
Cdd:TIGR00606  440 RTIELKKEILEKKQEELKFVIKELQQ----LEGSSDRILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADL 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1681 QELHSCLTKILDDLRlNHEVALTERAEVLQDNKNLLAEKREMMLRNEEAL---------------------KEKEKLEES 1739
Cdd:TIGR00606  514 DRKLRKLDQEMEQLN-HHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELtsllgyfpnkkqledwlhsksKEINQTRDR 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1740 YFILQKEISQLAQTNSHISaNLLESQSENRTLRKDK-----------SKLTLKIRELETLHSFTAAQTAEDAM--QIMEQ 1806
Cdd:TIGR00606  593 LAKLNKELASLEQNKNHIN-NELESKEEQLSSYEDKlfdvcgsqdeeSDLERLKEEIEKSSKQRAMLAGATAVysQFITQ 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1807 MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQE 1886
Cdd:TIGR00606  672 LTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1887 ENVKLAEELGRTRDEVTSHQKL-------EEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKAS-LQKSISLTSALL 1958
Cdd:TIGR00606  752 KLQKVNRDIQRLKNDIEEQETLlgtimpeEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSdLDRTVQQVNQEK 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1959 TEKDAELEKLRNEVTVLRG----ENATAKSLHSVVQTLESDKVKLELKVKNLElQLKENKRQLSS--SSGNTDAQAEEDE 2032
Cdd:TIGR00606  832 QEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ-QFEEQLVELSTevQSLIREIKDAKEQ 910

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937382  2033 RAQESQQMIDFLNSVIVDLQRKNQDLK---MKVEMMSEAALNGNG--EDLNSYDSDDQEKQSKKK 2092
Cdd:TIGR00606  911 DSPLETFLEKDQQEKEELISSKETSNKkaqDKVNDIKEKVKNIHGymKDIENKIQDGKDDYLKQK 975
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1488-1916 3.56e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1488 LGNIDALKKELQERKKENQELTSSKCDLSLL---LKEAQDAKKNLEKEHTSMIQAKDN---------LNAELKTCCCEKN 1555
Cdd:COG4717    70 LKELKELEEELKEAEEKEEEYAELQEELEELeeeLEELEAELEELREELEKLEKLLQLlplyqeleaLEAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1556 ML---LRDGLNLQEECQKLNEEIREIQQTLILEKE----ARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTEn 1628
Cdd:COG4717   150 ELeerLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE- 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1629 FTLTQEKTNSEQKVEEIIKEKELLSAETAQLAanIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEV 1708
Cdd:COG4717   229 LEQLENELEAAALEERLKEARLLLLIAAALLA--LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1709 LQdnknllAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHIsanllesQSENRTLRKDKSKLTLKIRELETL 1788
Cdd:COG4717   307 LQ------ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL-------QELLREAEELEEELQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1789 HSFTAAQTAEDamqimeqmtkektETLASLEDTKQTNARLQNELDTLKENnlktVEELNKSKELLSVENQKmEEFKKEIE 1868
Cdd:COG4717   374 ALLAEAGVEDE-------------EELRAALEQAEEYQELKEELEELEEQ----LEELLGELEELLEALDE-EELEEELE 435

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 568937382 1869 TLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLN 1916
Cdd:COG4717   436 ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKA 483
46 PHA02562
endonuclease subunit; Provisional
 626-891 3.61e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 3.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  626 EIESLQSKQDsersaHAKEMETMQAKLMKIIKEKEDsleAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKY 705
Cdd:PHA02562  182 QIQTLDMKID-----HIQQQIKTYNKNIEEQRKKNG---ENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  706 TEQSEVIGNFTSQLSAvkeKLLDLDALRKANSEGKlELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkelvL 785
Cdd:PHA02562  254 SAALNKLNTAAAKIKS---KIEQFQKVIKMYEKGG-VCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDE----L 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  786 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQdtvnklhQKEEQFNVLSSELEKLRENLTDmeaKFKEK 865
Cdd:PHA02562  326 EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQDELDK---IVKTK 395

                         250       260
                  ....*....|....*....|....*..
gi 568937382  866 DDredqlvKAKEKLENDIA-EIMKMSG 891
Cdd:PHA02562  396 SE------LVKEKYHRGIVtDLLKDSG 416
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1178-1707 3.62e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1178 LRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQM 1257
Cdd:COG4717    40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1258 SLdntcltlkaerENLLQTNRDLQfekdtlrqgqeklsasleatlqvkqllstEAETLRTQLDCASKALRKAELDMRQLQ 1337
Cdd:COG4717   120 KL-----------EKLLQLLPLYQ-----------------------------ELEALEAELAELPERLEELEERLEELR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1338 TSNSSLTKLLEEIKTCRAITDSECIQLLHEKEslaASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYL 1417
Cdd:COG4717   160 ELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELE----EELEQL 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1418 TSEKEVAcQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGDL-------------RRKYDQEATNRRIVMQE 1483
Cdd:COG4717   233 ENELEAA-ALEERLKEARLLLLIAAALLALLgLGGSLLSLILTIAGVLFLvlgllallflllaREKASLGKEAEELQALP 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1484 KMKLLGNIDaLKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM--IQAKDNLNAELKTCCCEKNMLLRDG 1561
Cdd:COG4717   312 ALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAA 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1562 LNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENnklhgrvvlLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQK 1641
Cdd:COG4717   391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE---------LEEELEELEEELEELEEELEELREELAELEAE 461

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382 1642 VEEIIKEKELlsaetAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAE 1707
Cdd:COG4717   462 LEQLEEDGEL-----AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1610-1797 3.66e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1610 LEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTK 1689
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1690 ILDDLRLNHEVAL------------------------TERAEVLQDNKNLLAEKREMMLRNEEALKE-KEKLEESYFILQ 1744
Cdd:COG4942   112 ALYRLGRQPPLALllspedfldavrrlqylkylaparREQAEELRADLAELAALRAELEAERAELEAlLAELEEERAALE 191

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568937382 1745 KEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1797
Cdd:COG4942   192 ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
386-815 3.72e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  386 EIEQELALARDGHDQHvLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKgdlevatvsEKSRI 465
Cdd:COG4717    75 ELEEELKEAEEKEEEY-AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEA---------ELAEL 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  466 MELEKDLALRAQEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALH 545
Cdd:COG4717   145 PERLEELEERLEELRELEEELEE------------LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELE 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  546 TATEKLSKENESLRSKLD-------HANKENSDVIALWKSKLETAIASHQQAMEELKVSFSK---------GIGTDSAEF 609
Cdd:COG4717   213 EELEEAQEELEELEEELEqleneleAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlGLLALLFLL 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  610 AELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQH----LVEMEDTL 685
Cdd:COG4717   293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeelqLEELEQEI 372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  686 NKLQeAEIKVKELEVLQAKYTEQSEVIgNFTSQLSAVKEKLLDLDALRKANSEgKLELETLRQQLEGAEKQIKNLETERN 765
Cdd:COG4717   373 AALL-AEAGVEDEEELRAALEQAEEYQ-ELKEELEELEEQLEELLGELEELLE-ALDEEELEEELEELEEELEELEEELE 449

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 568937382  766 AESSKANSITKELQEKElvltgLQDSLNQVNQVKETLEKELQTLKEKFAS 815
Cdd:COG4717   450 ELREELAELEAELEQLE-----EDGELAELLQELEELKAELRELAEEWAA 494
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1183-1926 3.97e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 3.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1183 DKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALV------QEIEDLTTEKKSAAEKQ 1256
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLRealqqtQQSHAYLTQKREAQEEQ 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1257 MSLDNTCLTLKAERENL--LQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMR 1334
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELraQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1335 Q---LQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASE--RTLLAEKEELLSENRIITEKLSKQSEEVArlemg 1409
Cdd:TIGR00618  336 QqssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQSLCKELDILQREQA----- 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1410 lneKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYD----QEATNRRIVMQEKM 1485
Cdd:TIGR00618  411 ---TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKereqQLQTKEQIHLQETR 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1486 KllgnidalKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEhTSMIQAKDNLNAELKTcccEKNMLLRDGLNLQ 1565
Cdd:TIGR00618  488 K--------KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL-TRRMQRGEQTYAQLET---SEEDVYHQLTSER 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1566 EECQKLNEEIREIQQTLILEKEARAKESEtslyENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLtQEKTNSEQKVEEI 1645
Cdd:TIGR00618  556 KQRASLKEQMQEIQQSFSILTQCDNRSKE----DIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL-LRKLQPEQDLQDV 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1646 IKEKELLSAETAQLAANIETLKSDFAAlsksklELQELHSCLTKILDDLRLNHEVALTERAevlQDNKNLLAEKREMMLR 1725
Cdd:TIGR00618  631 RLHLQQCSQELALKLTALHALQLTLTQ------ERVREHALSIRVLPKELLASRQLALQKM---QSEKEQLTYWKEMLAQ 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1726 NEEALKEKEKLEESYFILQKEISQLaqtnshisanlleSQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME 1805
Cdd:TIGR00618  702 CQTLLRELETHIEEYDREFNEIENA-------------SSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1806 QMTKEkTETLASLEDTKQTNARLQNELDTLkennlktveeLNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQ 1885
Cdd:TIGR00618  769 EVTAA-LQTGAELSHLAAEIQFFNRLREED----------THLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL 837

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 568937382  1886 EENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSL 1926
Cdd:TIGR00618  838 EEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 381-763 4.00e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  381 TSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEesiTKGDLEVA-- 457
Cdd:PRK04778   78 TNSLPDIEEQLFEAEELNDKfRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQ---LKDLYRELrk 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  458 TVSEKS-----RIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAI-------HTDHQGEMTS 525
Cdd:PRK04778  155 SLLANRfsfgpALDELEKQLENLEEEFSQFVELTESGDYVEAREILDQLEEELAALEQIMEEIpellkelQTELPDQLQE 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  526 LK--------EHFGAREEAFQKEIKALHTATEKLSKENESLrsKLDHANKENSDV---IALWKSKLETAIASHQQAMEEL 594
Cdd:PRK04778  235 LKagyrelveEGYHLDHLDIEKEIQDLKEQIDENLALLEEL--DLDEAEEKNEEIqerIDQLYDILEREVKARKYVEKNS 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  595 KVsFSKGIGTDSAEFAELKTQIERLRLDYQ---HEIESLQSkqdsersaHAKEMETMQAKLMKIIK----------EKED 661
Cdd:PRK04778  313 DT-LPDFLEHAKEQNKELKEEIDRVKQSYTlneSELESVRQ--------LEKQLESLEKQYDEITEriaeqeiaysELQE 383

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  662 SLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKVKE-LEVLQAK------YTEQSEVIGNFTSQLSAVKEKLLDLDALRK 734
Cdd:PRK04778  384 ELEEILKQLEEIEKEQ-EKLSEMLQGLRKDELEAREkLERYRNKlheikrYLEKSNLPGLPEDYLEMFFEVSDEIEALAE 462

                         410       420
                  ....*....|....*....|....*....
gi 568937382  735 ANSEGKLELETLRQQLEGAEKQIKNLETE 763
Cdd:PRK04778  463 ELEEKPINMEAVNRLLEEATEDVETLEEE 491
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 867-1076 4.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  867 DREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLK-AEQSQQQ 945
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEiAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  946 AARKHEEEKKELEEKLLELEKKMETSYNQCQDLKA----KYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDL 1021
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382 1022 MQDMEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1076
Cdd:COG4942   180 LAELEEERAALEALKAeRQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 624-865 4.35e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  624 QHEIESLQSKQDSERSAhAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKLQeaeikvKELEVLQA 703
Cdd:COG4942    26 EAELEQLQQEIAELEKE-LAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEAELAELE------KEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  704 KYTEQSEVIGNFtsqlsavkeklldLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkel 783
Cdd:COG4942    98 ELEAQKEELAEL-------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE--- 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  784 vLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 863
Cdd:COG4942   162 -LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 568937382  864 EK 865
Cdd:COG4942   241 ER 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 742-949 4.44e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  742 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLN----QVNQVKETLEKELQTLKEKFASTS 817
Cdd:COG3883    24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaeaEIEERREELGERARALYRSGGSVS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  818 E-EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQ 896
Cdd:COG3883   104 YlDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568937382  897 LTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARK 949
Cdd:COG3883   184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
mukB PRK04863
chromosome partition protein MukB;
532-933 4.47e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  532 ARE---EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALW-KSKLETAIASHQQAMEELkvsfskgigtdSA 607
Cdd:PRK04863  783 AREkriEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfEADPEAELRQLNRRRVEL-----------ER 851

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  608 EFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAvkARLDSAEDQHLVEMEDTLNK 687
Cdd:PRK04863  852 ALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEA--KRFVQQHGNALAQLEPIVSV 929

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  688 LQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLE-----LETLRQQLEGAEKQIKNLET 762
Cdd:PRK04863  930 LQSDP---EQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAknsdlNEKLRQRLEQAEQERTRARE 1006

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  763 E-RNAESskansitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQtrmQDTVNK-LHQKEEQ 840
Cdd:PRK04863 1007 QlRQAQA--------QLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR---RDELHArLSANRSR 1075

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  841 FNVLSSELEKLRENLTDMEAKFK--EKD--DREDQLVKAKekleNDIAEIMKMSGDNSsqltkmnDELRLKERSVEELql 916
Cdd:PRK04863 1076 RNQLEKQLTFCEAEMDNLTKKLRklERDyhEMREQVVNAK----AGWCAVLRLVKDNG-------VERRLHRRELAYL-- 1142

                         410
                  ....*....|....*..
gi 568937382  917 kltKANENASFLQKSIG 933
Cdd:PRK04863 1143 ---SADELRSMSDKALG 1156
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 535-825 4.73e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.87  E-value: 4.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  535 EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAE----FA 610
Cdd:COG5185   242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  611 ELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEdsLEAVKARLDSAEDQHLVEMEDTLNKLQE 690
Cdd:COG5185   322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  691 AEIKVKE-LEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESS 769
Cdd:COG5185   400 QRGYAQEiLATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSK 479

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937382  770 KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQT 825
Cdd:COG5185   480 KEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGY 535
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
612-797 4.89e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 4.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  612 LKTQIERLR---LDYQHEIESLQSKQ-----DSERSAHAKEMETMQAKLMKI---IKEKEDSLEAVKARLDSAEDQHLVE 680
Cdd:COG3206   180 LEEQLPELRkelEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEAraeLAEAEARLAALRAQLGSGPDALPEL 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  681 MEDT-----LNKLQEAEIkvkELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLD-----LDALRKANSEGKLELETLRQQL 750
Cdd:COG3206   260 LQSPviqqlRAQLAELEA---ELAELSARYTPNHPDVIALRAQIAALRAQLQQeaqriLASLEAELEALQAREASLQAQL 336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 568937382  751 EGAEKQIKNLeterNAESSKANSITKELQEKELVLTGLQDSLNQVNQ 797
Cdd:COG3206   337 AQLEARLAEL----PELEAELRRLEREVEVARELYESLLQRLEEARL 379
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 404-996 5.76e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.96  E-value: 5.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   404 ELEAKMDQLRTMVEAADRekvelLNQLEEEKRKVEDLQFRVEEESITKgDLEVATVSEKSRIMELEKDLALRAQEVAELR 483
Cdd:TIGR00606  455 ELKFVIKELQQLEGSSDR-----ILELDQELRKAERELSKAEKNSLTE-TLKKEVKSLQNEKADLDRKLRKLDQEMEQLN 528

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   484 RRLESSKppgdvdMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREE------AFQKEIKALHTATEKLSKENES 557
Cdd:TIGR00606  529 HHTTTRT------QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQledwlhSKSKEINQTRDRLAKLNKELAS 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   558 LRSKLDHANKENSDVIA---------------------LWKSKLETAIASHQQAMEELKVSFSKGIGTDS---------- 606
Cdd:TIGR00606  603 LEQNKNHINNELESKEEqlssyedklfdvcgsqdeesdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLtdenqsccpv 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   607 --------AEFAELKTQIE---RLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKE------KEDSLEAVKAR 669
Cdd:TIGR00606  683 cqrvfqteAELQEFISDLQsklRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEipelrnKLQKVNRDIQR 762

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   670 LDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDA--LRKANSEGKLELETLR 747
Cdd:TIGR00606  763 LKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVqqVNQEKQEKQHELDTVV 842

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   748 QQLE-------GAEKQIKNLETERNAESSKANSITKELQ--------------EKELVLTGLQDSLNQVNQVKETLEKEL 806
Cdd:TIGR00606  843 SKIElnrkliqDQQEQIQHLKSKTNELKSEKLQIGTNLQrrqqfeeqlvelstEVQSLIREIKDAKEQDSPLETFLEKDQ 922

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   807 QTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREN-LTDMEAKFKEKDDREDQLVKAKEKLENDIAE 885
Cdd:TIGR00606  923 QEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDyLKQKETELNTVNAQLEECEKHQEKINEDMRL 1002

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   886 IMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTL---KAEQSQQQAARKHEEEKKELEE-KL 961
Cdd:TIGR00606 1003 MRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQehqKLEENIDLIKRNHVLALGRQKGyEK 1082

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 568937382   962 LELEKKMETSYNQCQDLKAKYEKASSETKTKHEEI 996
Cdd:TIGR00606 1083 EIKHFKKELREPQFRDAEEKYREMMIVMRTTELVN 1117
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1837-2092 5.76e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.87  E-value: 5.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1837 ENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSA-LQEENVKLAEELGRTRDEVTSHQKLEEERSVL 1915
Cdd:COG5185   232 EEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKrLNENANNLIKQFENTKEKIAEYTKSIDIKKAT 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1916 NNQLLEMKKSLPSNTL--RESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGEnataKSLHSVVQTLE 1993
Cdd:COG5185   312 ESLEEQLAAAEAEQELeeSKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSS----EELDSFKDTIE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1994 SDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAqesqqmIDFLNSVIVDLQRKNQDL-KMKVEMMSEAALNG 2072
Cdd:COG5185   388 STKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQ------IEQATSSNEEVSKLLNELiSELNKVMREADEES 461

                         250       260
                  ....*....|....*....|
gi 568937382 2073 NGEDLNSYDSDDQEKQSKKK 2092
Cdd:COG5185   462 QSRLEEAYDEINRSVRSKKE 481
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
974-1160 5.86e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 5.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  974 QCQDLKAKYEKASSETKT--KHEEILQNLQKmLADTEDKLKAAQEANRDLMQDMEElktqadkaksltylLTSAKKEIEV 1051
Cdd:COG4913   625 ELAEAEERLEALEAELDAlqERREALQRLAE-YSWDEIDVASAEREIAELEAELER--------------LDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1052 MSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQklwsvnetlHLEKERVSEEKQVAEKRYQQEHR 1131
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE---------AAEDLARLELRALLEERFAAALG 760

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568937382 1132 D------RESLVAEREKLLKEINAAQEELLKMHME 1160
Cdd:COG4913   761 DaverelRENLEERIDALRARLNRAEEELERAMRA 795
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 506-1345 6.21e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.96  E-value: 6.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   506 SALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENS------DVIALWKSK 579
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGrlqlqaDRHQEHIRA 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   580 LETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQ--------IERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAK 651
Cdd:TIGR00606  366 RDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIErqedeaktAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELK 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   652 LMKIIKEKEDsLEAVKARLDSAE---------DQHLVEMEDTLNKLQE---AEIKVKELEVLQA--------------KY 705
Cdd:TIGR00606  446 KEILEKKQEE-LKFVIKELQQLEgssdrilelDQELRKAERELSKAEKnslTETLKKEVKSLQNekadldrklrkldqEM 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   706 TEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETlrqqLEGAEKQIKNLETERNAESSKANSITKELQEKELVL 785
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTS----LLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   786 TGLQDSLNQVNQVKETLEKELQTLKEKF--ASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 863
Cdd:TIGR00606  601 ASLEQNKNHINNELESKEEQLSSYEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCC 680

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   864 EKDDREdqlVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQ 943
Cdd:TIGR00606  681 PVCQRV---FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVN 757

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   944 QQAARKHEEEKKELEEKLLELEKkmETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMlaDTEDKLKAAQEANRDLMQ 1023
Cdd:TIGR00606  758 RDIQRLKNDIEEQETLLGTIMPE--EESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL--QGSDLDRTVQQVNQEKQE 833

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1024 DMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEK-QLYAQEANALKLEKgsllskliEVETKITLLQEdqqklw 1102
Cdd:TIGR00606  834 KQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKlQIGTNLQRRQQFEE--------QLVELSTEVQS------ 899

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1103 sVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEAskvsmQVLIEELRFCK 1182
Cdd:TIGR00606  900 -LIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIEN-----KIQDGKDDYLK 973

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1183 DKLMAMSeKARAEKEHLEGQVKKLTAENLVLVKDKDDviqklQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNT 1262
Cdd:TIGR00606  974 QKETELN-TVNAQLEECEKHQEKINEDMRLMRQDIDT-----QKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQM 1047

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1263 CLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSAsleatlqvKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSS 1342
Cdd:TIGR00606 1048 QVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYE--------KEIKHFKKELREPQFRDAEEKYREMMIVMRTTELVNKD 1119


                   ...
gi 568937382  1343 LTK 1345
Cdd:TIGR00606 1120 LDI 1122
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1275-1504 7.38e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1275 QTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRK-------AELDMRQLQTSNSSLTKLL 1347
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAleqelaaLEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382 1348 EEIKTCRAitdseciqllhekESLAASERTLLAEKEELLSENRIITEkLSKQSEEVARLEMGLNEKITYLTSEKEVACQK 1427
Cdd:COG4942   100 EAQKEELA-------------ELLRALYRLGRQPPLALLLSPEDFLD-AVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937382 1428 VAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKE 1504
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 577-794 7.70e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  577 KSKLETAIASHQQAMEELKvsfsKGIGTDSAEFAELKTQIERLrldyqheiESLQSKQDSERSAHAKEMETMQAKLMKII 656
Cdd:COG4942    29 LEQLQQEIAELEKELAALK----KEEKALLKQLAALERRIAAL--------ARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  657 KEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN 736
Cdd:COG4942    97 AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382  737 SEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQ 794
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 331-683 7.72e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   331 RTGLLTETSSRYARKISGTTALQEA---LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlardghdqhvlELEA 407
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDAsrkIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE-----------NVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   408 KMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSekSRIMELEKDLALRaqevaELRRRLE 487
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIE--ARLREIEQKLNRL-----TLEKEYL 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   488 SSKPPGDVDMSLSLLQEISALQEKLEAIHTDhqgemtslKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANK 567
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGK--------KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382   568 EnsdvialwKSKLETAIASHQQAMEELKVsfskgigTDSAEFAELKtQIERLRLDYQHEIESLQSKQD--SERSAHAKEM 645
Cdd:TIGR02169  904 K--------IEELEAQIEKKRKRLSELKA-------KLEALEEELS-EIEDPKGEDEEIPEEELSLEDvqAELQRVEEEI 967

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 568937382   646 ETMQAKLMKIIKEKEDsleaVKARLDSAEDQHLVEMED 683
Cdd:TIGR02169  968 RALEPVNMLAIQEYEE----VLKRLDELKEKRAKLEEE 1001
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1075-1835 8.52e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.36  E-value: 8.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1075 LEKGSLLSKLIEVETKITLLQEDQQKLwsvnETLHLEKERVSeekqvaekryqQEHRDRESLVAEREKLLKEINAAQEEL 1154
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTL----ESAELRLSHLH-----------FGYKSDETLIASRQEERQETSAELNQL 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1155 LkmhmenDSLEASkvsMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKD 1234
Cdd:pfam12128  292 L------RTLDDQ---WKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEER 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1235 QKALVQEIEDLTtEKKSAAEKQMSLDNtcltlKAEREnllqtnrDLQFEKDTLRQGQEKLSASLEATLQ-VKQLLSTEAE 1313
Cdd:pfam12128  363 LKALTGKHQDVT-AKYNRRRSKIKEQN-----NRDIA-------GIKDKLAKIREARDRQLAVAEDDLQaLESELREQLE 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1314 TLRTQLDCASK--ALRKAELDMRQLQTSNSSLTKLLEEIKTCRA-ITDSECIQLLHEKESLAASERTLLAEKEELLSENR 1390
Cdd:pfam12128  430 AGKLEFNEEEYrlKSRLGELKLRLNQATATPELLLQLENFDERIeRAREEQEAANAEVERLQSELRQARKRRDQASEALR 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1391 IITEKLSKQSEEVARLEMGLNEK----ITYLTSEKEVACQKVAKL-------------------KKQQDSLLKEKSALEL 1447
Cdd:pfam12128  510 QASRRLEERQSALDELELQLFPQagtlLHFLRKEAPDWEQSIGKVispellhrtdldpevwdgsVGGELNLYGVKLDLKR 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1448 QNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLL-GNIDALKKELQERKkenQELTSSKCDLSLLLKEAQDAK 1526
Cdd:pfam12128  590 IDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAnGELEKASREETFAR---TALKNARLDLRRLFDEKQSEK 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1527 KNLEKEHTSmiqAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILE-------KEARAKESETSLYE 1599
Cdd:pfam12128  667 DKKNKALAE---RKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVvegaldaQLALLKAAIAARRS 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1600 NNKLH-------------------GRVVLLEEEIQRL------------------RVCSEQLQTENFTLTQEKTNSEQKV 1642
Cdd:pfam12128  744 GAKAElkaletwykrdlaslgvdpDVIAKLKREIRTLerkieriavrrqevlryfDWYQETWLQRRPRLATQLSNIERAI 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1643 EEIIKEKELLSAETAQLAANIETlksDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEvlQDNKNLLAEKREM 1722
Cdd:pfam12128  824 SELQQQLARLIADTKLRRAKLEM---ERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQ--GSIGERLAQLEDL 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1723 MLRNEEALKEKEKLEESY--FILQKEISQLAQTNSHISANlLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDA 1800
Cdd:pfam12128  899 KLKRDYLSESVKKYVEHFknVIADHSGSGLAETWESLREE-DHYQNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLREQ 977

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 568937382  1801 MQIMEQMTKEKTETLASLED-TKQTNARLQNELDTL 1835
Cdd:pfam12128  978 VSILGVDLTEFYDVLADFDRrIASFSRELQREVGEE 1013
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1491-1870 8.84e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.16  E-value: 8.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1491 IDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEhtsmiqakdnlnaeLKTCCCEKNMLLRDGLNLQEECQK 1570
Cdd:TIGR04523  372 IEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ--------------IKKLQQEKELLEKEIERLKETIIK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1571 LNEEIREiqqtliLEKEARAKESETslyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKE 1650
Cdd:TIGR04523  438 NNSEIKD------LTNQDSVKELII-----KNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKK 506

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1651 LLSAETAQLAANIETLKSDFAALSKSKLEL-QELHSCLTKIL-DDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEE 1728
Cdd:TIGR04523  507 ELEEKVKDLTKKISSLKEKIEKLESEKKEKeSKISDLEDELNkDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1729 ALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAaQTAEDAMQIMEQMT 1808
Cdd:TIGR04523  587 KQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK-ETIKEIRNKWPEII 665

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937382  1809 KEKTETLASLEDTKQTNARLQNELDTLKENNLKT------VEELNKSKELLSVENQKMEEFKKEIETL 1870
Cdd:TIGR04523  666 KKIKESKTKIDDIIELMKDWLKELSLHYKKYITRmirikdLPKLEEKYKEIEKELKKLDEFSKELENI 733
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1040-1436 9.63e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 9.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1040 YLLTSAKKEIEVMSEELRGLKSEkqlYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKlwsvNETLHLEKERVSEEK 1119
Cdd:pfam17380  233 YEKMERRKESFNLAEDVTTMTPE---YTVRYNGQTMTENEFLNQLLHIVQHQKAVSERQQQ----EKFEKMEQERLRQEK 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1120 QVAEKRYQQEHRDRESLVAEREKLLKE--INAAQEellKMHMENDSlEASKVSMQVLIEELRFCKDKLMAMSEKARAEKE 1197
Cdd:pfam17380  306 EEKAREVERRRKLEEAEKARQAEMDRQaaIYAEQE---RMAMERER-ELERIRQEERKRELERIRQEEIAMEISRMRELE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1198 HLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSldntclTLKAERENLLQTN 1277
Cdd:pfam17380  382 RLQMERQQKNER----VRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVR------RLEEERAREMERV 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1278 RDLQFEKDTlrqgqeklsasleatlQVKQLLSTEAETLRTQLDCASKALRKAELDmrqlQTSNSSLTKLLEEIKtcRAIT 1357
Cdd:pfam17380  452 RLEEQERQQ----------------QVERLRQQEEERKRKKLELEKEKRDRKRAE----EQRRKILEKELEERK--QAMI 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937382  1358 DSECIQLLHEKE------SLAASERTLLAE----KEELLSENRIITEKLSKQSEEVARLEMglnekityLTSEKEVACQK 1427
Cdd:pfam17380  510 EEERKRKLLEKEmeerqkAIYEEERRREAEeerrKQQEMEERRRIQEQMRKATEERSRLEA--------MEREREMMRQI 581


                   ....*....
gi 568937382  1428 VAKLKKQQD 1436
Cdd:pfam17380  582 VESEKARAE 590
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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