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Conserved domains on  [gi|568937372|ref|XP_006530473|]
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CAP-Gly domain-containing linker protein 1 isoform X3 [Mus musculus]

Protein Classification

CAP_GLY and CLIP1_ZNF domain-containing protein( domain architecture ID 13652084)

protein containing domains CAP_GLY, CCDC14, UPF0242, and CLIP1_ZNF

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.70e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.70e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.36e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.36e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1047-1919 3.52e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.52e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1047 QKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLYAQEANA 1118
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1119 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1198
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1199 ELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkkltaenlvlVKDKDDVIQKLQSAYEELV 1278
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1279 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTclTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1358
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQE--IEELLKKLEEAELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1359 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqllhEKESLAASERTLLAEKEELLSENRII 1438
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1439 TEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGD 1511
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1512 LRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTsmIQAKDN 1588
Cdd:TIGR02168  606 DLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1589 lnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSE 1668
Cdd:TIGR02168  678 ---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1669 QLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL 1748
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1749 TERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDK 1821
Cdd:TIGR02168  831 RRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1822 SKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLEDTKQTNAR-----LQNELDTLKENNLK 1887
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKIEDDEEEARrrlkrLENKIKELGPVNLA 990

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568937372  1888 TVEELNKSKELLSVENQKMEEFKKEIETLKQA 1919
Cdd:TIGR02168  991 AIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 634-1432 1.24e-20

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 100.14  E-value: 1.24e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   634 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 710
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   711 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 790
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   791 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 870
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   871 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   944 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 1009
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1010 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1072
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1073 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1129
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1130 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1208
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1209 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1288
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1289 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1368
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372  1369 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1432
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-905 1.62e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 76.70  E-value: 1.62e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   425 ELLNQLEEE---------KRKVEDLQFrvEEESITKGDLEQKSPISEDPENTQTKLEHARTKELEQSLLFEKTKADKLQR 495
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQF--SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   496 ELEDTRVatvsEKSRIMELEKDLALRAQ------------------EVAELRRRLESSKppgdvDMSLSLLQEISALQEK 557
Cdd:pfam15921  420 ELDDRNM----EVQRLEALLKAMKSECQgqmerqmaaiqgknesleKVSSLTAQLESTK-----EMLRKVVEELTAKKMT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   558 LEAIHTDHQGEMTSLKEHFGAREeAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIAS 632
Cdd:pfam15921  491 LESSERTVSDLTASLQEKERAIE-ATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILRQ 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   633 HQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAV 712
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAV 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   713 KaRLDSAEDQHLVEMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLsavkeklldldalrkansegKLELETL 792
Cdd:pfam15921  649 K-DIKQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKSA 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   793 RQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTR 872
Cdd:pfam15921  705 QSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE 784

                          570       580       590
                   ....*....|....*....|....*....|...
gi 568937372   873 MQDTVNKLHqkeeqfnVLSSELEKLRENLTDME 905
Cdd:pfam15921  785 KNKMAGELE-------VLRSQERRLKEKVANME 810
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2173-2189 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 568937372  2173 RPYCEICEMFGHWATNC 2189
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
1740-2131 4.51e-07

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.47  E-value: 4.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1740 LRLNHEVALTERAEVLQDN--KNLLAEKREMMLRNE----EALKEKEKLEESYFILQ---KEISQLAQTNSHISANLLE- 1809
Cdd:COG5022   832 LRETEEVEFSLKAEVLIQKfgRSLKAKKRFSLLKKEtiylQSAQRVELAERQLQELKidvKSISSLKLVNLELESEIIEl 911

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1810 SQSENRTLRKDKSKLTLKIRELETLHsftaaqtaeDAMQIMEQMTKEKTEtlasledtKQTNARLQNELDTLKENNlKTV 1889
Cdd:COG5022   912 KKSLSSDLIENLEFKTELIARLKKLL---------NNIDLEEGPSIEYVK--------LPELNKLHEVESKLKETS-EEY 973

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1890 EELNKSKELLSVENQKMEEfkkEIETLKQAAAQKSQQLSALQEEnvklAEELGRTRDEVTSHQKleeersvlnnqllemk 1969
Cdd:COG5022   974 EDLLKKSTILVREGNKANS---ELKNFKKELAELSKQYGALQES----TKQLKELPVEVAELQS---------------- 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1970 krESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELq 2048
Cdd:COG5022  1031 --ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2049 lkeNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQS 2128
Cdd:COG5022  1104 ---TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEK 1180


                  ...
gi 568937372 2129 KKK 2131
Cdd:COG5022  1181 RLY 1183
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2133-2150 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 568937372  2133 RLFCDICDCFDlHDTEDC 2150
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.70e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.70e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.36e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.36e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 5.20e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.44  E-value: 5.20e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372    213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.53e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.53e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1047-1919 3.52e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.52e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1047 QKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLYAQEANA 1118
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1119 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1198
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1199 ELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkkltaenlvlVKDKDDVIQKLQSAYEELV 1278
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1279 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTclTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1358
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQE--IEELLKKLEEAELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1359 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqllhEKESLAASERTLLAEKEELLSENRII 1438
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1439 TEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGD 1511
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1512 LRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTsmIQAKDN 1588
Cdd:TIGR02168  606 DLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1589 lnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSE 1668
Cdd:TIGR02168  678 ---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1669 QLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL 1748
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1749 TERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDK 1821
Cdd:TIGR02168  831 RRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1822 SKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLEDTKQTNAR-----LQNELDTLKENNLK 1887
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKIEDDEEEARrrlkrLENKIKELGPVNLA 990

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568937372  1888 TVEELNKSKELLSVENQKMEEFKKEIETLKQA 1919
Cdd:TIGR02168  991 AIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 634-1432 1.24e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 100.14  E-value: 1.24e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   634 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 710
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   711 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 790
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   791 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 870
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   871 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   944 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 1009
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1010 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1072
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1073 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1129
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1130 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1208
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1209 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1288
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1289 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1368
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372  1369 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1432
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 709-1291 1.94e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.94e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  709 LEAVKARLDSAEDqHLVEMEDTLNKLQ-EAEIKVK------ELEVLQAKYteqsevignftsQLSAVKEKLLDLDALRKA 781
Cdd:COG1196   181 LEATEENLERLED-ILGELERQLEPLErQAEKAERyrelkeELKELEAEL------------LLLKLRELEAELEELEAE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  782 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANS-------ITKELQEKELVLTGLQDSLNQVNQVKETLEKELQT 854
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyeLLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  855 LKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 934
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  935 MSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQ--SQQQAARKHEEEKKELEEKLLELEK 1012
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELA 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1013 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQ----KMLADTEDKLKAAQEA------NRDLMQDMEELKTQADKAK 1082
Cdd:COG1196   488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLK 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1083 SLT------YLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1156
Cdd:COG1196   568 AAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1157 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckDKLMAMSE 1236
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER---LEEELEEE 724

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568937372 1237 KARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1291
Cdd:COG1196   725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1052-1663 8.81e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 8.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1052 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1122
Cdd:COG1196   176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1123 KGSLLSKLIEVETKITLLQEDQQKLwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1202
Cdd:COG1196   255 LEELEAELAELEAELEELRLELEEL-------ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1203 MHMENDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQK 1282
Cdd:COG1196   328 LEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1283 ALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1362
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1363 TQLDcASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEK- 1441
Cdd:COG1196   484 EELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAa 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1442 --LSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADResSIKTIGDLRRKYDQE 1519
Cdd:COG1196   563 ieYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1520 ATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELktcccE 1599
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-----E 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372 1600 KNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRL 1663
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-905 1.62e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 76.70  E-value: 1.62e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   425 ELLNQLEEE---------KRKVEDLQFrvEEESITKGDLEQKSPISEDPENTQTKLEHARTKELEQSLLFEKTKADKLQR 495
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQF--SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   496 ELEDTRVatvsEKSRIMELEKDLALRAQ------------------EVAELRRRLESSKppgdvDMSLSLLQEISALQEK 557
Cdd:pfam15921  420 ELDDRNM----EVQRLEALLKAMKSECQgqmerqmaaiqgknesleKVSSLTAQLESTK-----EMLRKVVEELTAKKMT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   558 LEAIHTDHQGEMTSLKEHFGAREeAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIAS 632
Cdd:pfam15921  491 LESSERTVSDLTASLQEKERAIE-ATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILRQ 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   633 HQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAV 712
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAV 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   713 KaRLDSAEDQHLVEMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLsavkeklldldalrkansegKLELETL 792
Cdd:pfam15921  649 K-DIKQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKSA 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   793 RQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTR 872
Cdd:pfam15921  705 QSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE 784

                          570       580       590
                   ....*....|....*....|....*....|...
gi 568937372   873 MQDTVNKLHqkeeqfnVLSSELEKLRENLTDME 905
Cdd:pfam15921  785 KNKMAGELE-------VLRSQERRLKEKVANME 810
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 659-1364 5.82e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.77  E-value: 5.82e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   659 KTQIERLRLDYQHEIESLQSKQDSERSAHAKE-------METMQAKLMKIIKEKeDSLEAVKARLDSAEDQHLVEMEDTL 731
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQkfylrqsVIDLQTKLQEMQMER-DAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   732 NKLQEAE-IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDAL--RKANSEGKLELETLRQQLEGAEKQIKNLET 808
Cdd:pfam15921  152 HELEAAKcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   809 ERNAESSKANSITKELQ--------EKELVLTGLQDslnQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM----QDT 876
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEalksesqnKIELLLQQHQD---RIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQA 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   877 VNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK-DDREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDEL-- 950
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLhk 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   951 RLKERSVEELQLKLTKANENASFLqkSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDlKAKYEK 1030
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQR---------------LEALLKAMKSECQG-QMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1031 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1110
Cdd:pfam15921  451 AAIQGKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1111 LYAQEANALKLEKGSLLSKLIEVET-KITLLQEDQqklwsVNETLHLEKERVSEekqvaekRYQQEHRDRESLVAEREKL 1189
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDK-----VIEILRQQIENMTQ-------LVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1190 LKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARAEKEhlegqVKKLTAENLVLVKDKDDVIQ 1268
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAVKD-----IKQERDQLLNEVKTSRNELN 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1269 KLQSAYEELVKDQKALVQEIEDLTTE-KKSAAEKQMSLDNTCLTLK---------------------AERENLLQTNRDL 1326
Cdd:pfam15921  671 SLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmqkqitAKRGQIDALQSKI 750

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 568937372  1327 QF----------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1364
Cdd:pfam15921  751 QFleeamtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1536-2114 1.73e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.17  E-value: 1.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1536 NIDALKKELQERKKENQELTSSKCDLslllkeaQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRdglnLQEECQ 1615
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENI-------EELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1616 KLNEEIREIQ-QTLILEKEARAKESETSLYEN--NKLHGRVVLLEEEIQRLRVCsEQLQTENFTLTQEKTNSEQKVEEII 1692
Cdd:PRK03918  235 ELKEEIEELEkELESLEGSKRKLEEKIRELEEriEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1693 KEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEV-ALTERAEVLQDN-KNLLAEKREMML 1770
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRlTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1771 rnEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLEsqsenrtLRKDKSKLTLKIRELETLH--SFTAAQTAEdamq 1848
Cdd:PRK03918  394 --EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHrkELLEEYTAE---- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1849 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE--NNLKTVEELNKSKELLSVEN-QKMEEFKKEIETLKQAAAQKSQ 1925
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1926 QLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLL--------EMKKRESEFR---------KDADEEKASLQK 1988
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEelgfesveELEERLKELEpfyneylelKDAEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1989 SISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQ 2066
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 568937372 2067 AEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2114
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 3.12e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 72.03  E-value: 3.12e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937372  211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
340-934 4.61e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 4.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSPISEDPENTQTKLehartKELEQSLLFEKTKADKLQRELED 499
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-----REIEKRLSRLEEEINGIEERIKE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  500 TRvatvSEKSRIMELEKdlalraqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEaihtdhqgemtSLKEHFGAR 579
Cdd:PRK03918  333 LE----EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  580 E-EAFQKEIKALHTATEKLSKENESLRSKldhankensdvialwKSKLETAIASHQQAMEELKVsfskgigtdsaefAEL 658
Cdd:PRK03918  385 TpEKLEKELEELEKAKEEIEEEISKITAR---------------IGELKKEIKELKKAIEELKK-------------AKG 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  659 KTQIERLRLDYQHEIEsLQSKQDSERSAHAKEMETMQAKLMKIIKEKedsleaVKARLDSAEDQHLVEMEDTLNKLQEAE 738
Cdd:PRK03918  437 KCPVCGRELTEEHRKE-LLEEYTAELKRIEKELKEIEEKERKLRKEL------RELEKVLKKESELIKLKELAEQLKELE 509

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  739 IKVKE--LEVLQAKYTEQSEV---IGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAE 813
Cdd:PRK03918  510 EKLKKynLEELEKKAEEYEKLkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEE 589

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  814 SSKANSITKELQEKELVLTGLQDSLnqvnqvkETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNV---- 889
Cdd:PRK03918  590 LEERLKELEPFYNEYLELKDAEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeye 662

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 568937372  890 -LSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 934
Cdd:PRK03918  663 eLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 9.56e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.02  E-value: 9.56e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 335-807 5.65e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 5.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA---RDGHDQHVLELEAKMDQ 411
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAeeeLEEAEAELAEAEEALLE 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  412 LRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKspisEDPENTQTKLEHARTKELEQSLLFEKTKAD 491
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER----LERLEEELEELEEALAELEEEEEEEEEALE 445

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  492 KLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQE-------ISALQEKLEAIHTD 564
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvkAALLLAGLRGLAGA 525

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  565 HQGEMTSLKEHFGAREEAFQKEIKALHTATE----------KLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQ 634
Cdd:COG1196   526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDevaaaaieylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  635 QAMEELKVSFSKGIGTDSAEFAELKTQIERLR----LDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLE 710
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  711 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEgkLELE 790
Cdd:COG1196   686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP--PDLE 763

                         490
                  ....*....|....*..
gi 568937372  791 TLRQQLEGAEKQIKNLE 807
Cdd:COG1196   764 ELERELERLEREIEALG 780
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1387-2056 3.00e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.43  E-value: 3.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1387 SSLTKLLEEIKTCRAITDSEciqlLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGL---NEKITYL 1463
Cdd:pfam05483   81 SKLYKEAEKIKKWKVSIEAE----LKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikeNNATRHL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1464 TSEKEVACQKVAKLKKQQDSLLKEKSALELqngDLLADRESSIKTIGDLRrkydQEATNRRIVMQEKMKL-LGNIDALKK 1542
Cdd:pfam05483  157 CNLLKETCARSAEKTKKYEYEREETRQVYM---DLNNNIEKMILAFEELR----VQAENARLEMHFKLKEdHEKIQHLEE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1543 ELQER--KKENQ---------ELTSSKCDLSLLLKEAQDAKKNLEKEHT-------SMIQAKDNLNAELKTCCCEKNMLL 1604
Cdd:pfam05483  230 EYKKEinDKEKQvsllliqitEKENKMKDLTFLLEESRDKANQLEEKTKlqdenlkELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1605 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEE----EIQRLRVCSEQLQTENFTLtQE 1680
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtEQQRLEKNEDQLKIITMEL-QK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1681 KTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILD-------DLRLNHEVALTERAE 1753
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQarekeihDLEIQLTAIKTSEEH 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1754 VLQDNKNLLAEKREMMLRNEEALKEKEKLeesyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELET 1833
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKL-------LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1834 lhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEI 1913
Cdd:pfam05483  542 ----KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEN 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1914 ETLKQAAAQKSQQLSALQEENVKLAEELGRTRDE----VTSHQKLEEERSVLNNQLLEmkkrESEFRKDADEEKASLQKS 1989
Cdd:pfam05483  618 KALKKKGSAENKQLNAYEIKVNKLELELASAKQKfeeiIDNYQKEIEDKKISEEKLLE----EVEKAKAIADEAVKLQKE 693

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372  1990 ISL-TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2056
Cdd:pfam05483  694 IDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2173-2189 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 568937372  2173 RPYCEICEMFGHWATNC 2189
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1740-2131 4.51e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.47  E-value: 4.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1740 LRLNHEVALTERAEVLQDN--KNLLAEKREMMLRNE----EALKEKEKLEESYFILQ---KEISQLAQTNSHISANLLE- 1809
Cdd:COG5022   832 LRETEEVEFSLKAEVLIQKfgRSLKAKKRFSLLKKEtiylQSAQRVELAERQLQELKidvKSISSLKLVNLELESEIIEl 911

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1810 SQSENRTLRKDKSKLTLKIRELETLHsftaaqtaeDAMQIMEQMTKEKTEtlasledtKQTNARLQNELDTLKENNlKTV 1889
Cdd:COG5022   912 KKSLSSDLIENLEFKTELIARLKKLL---------NNIDLEEGPSIEYVK--------LPELNKLHEVESKLKETS-EEY 973

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1890 EELNKSKELLSVENQKMEEfkkEIETLKQAAAQKSQQLSALQEEnvklAEELGRTRDEVTSHQKleeersvlnnqllemk 1969
Cdd:COG5022   974 EDLLKKSTILVREGNKANS---ELKNFKKELAELSKQYGALQES----TKQLKELPVEVAELQS---------------- 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1970 krESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELq 2048
Cdd:COG5022  1031 --ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2049 lkeNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQS 2128
Cdd:COG5022  1104 ---TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEK 1180


                  ...
gi 568937372 2129 KKK 2131
Cdd:COG5022  1181 RLY 1183
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-849 3.87e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDqhvleleakmdqlrtmV 416
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAG----------------L 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  417 EAADREKVELlnQLEEEKRKVEDLQFRVEEESITKGDLeqkspisedpeNTQTKLEHARTKELEQSLLFEKTKADKLQRE 496
Cdd:PRK02224  305 DDADAEAVEA--RREELEDRDEELRDRLEECRVAAQAH-----------NEEAESLREDADDLEERAEELREEAAELESE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  497 LEDTRVATVSEKSRIMELEKdlalraqEVAELRRRLESSkpPGDVDMSLSLLQEisaLQEKLEAIHTDHQGEMTSLKEHF 576
Cdd:PRK02224  372 LEEAREAVEDRREEIEELEE-------EIEELRERFGDA--PVDLGNAEDFLEE---LREERDELREREAELEATLRTAR 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  577 GAREEAFQ--------------KEIKALHTATEKlSKENESLRSKLDHANKENSDVialwKSKLETA-----IASHQQAM 637
Cdd:PRK02224  440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEED-RERVEELEAELEDLEEEVEEV----EERLERAedlveAEDRIERL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  638 EELKVSFSKGIGTDSAEFAELKTQIERLRldyqHEIESLQSKQDSERSAHAKEMETMQAKLMKiIKEKEDSLEAVKARLD 717
Cdd:PRK02224  515 EERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREE-VAELNSKLAELKERIE 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  718 SAEDqhlveMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN--SEGKLELETLRQQ 795
Cdd:PRK02224  590 SLER-----IRTLLAAIADAE---DEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEY 661

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568937372  796 LEGAEKQIKNLETERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETLE 849
Cdd:PRK02224  662 LEQVEEKLDELREERDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
PRK11281 PRK11281
mechanosensitive channel MscK;
1870-2087 7.41e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.45  E-value: 7.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1870 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1942
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1943 --RTRDEVTSHQKLEEERSVLNNQLLEMKKRESEfrkdADEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENAT 2020
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDLAE----YNSQLVSLQTQPERAQAALYANSQRLQQIRNL---LKGGKVG 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937372 2021 AKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEED---ERAQESQQMIDFLNSVI 2087
Cdd:PRK11281  186 GKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDyltARIQRLEHQLQLLQEAI 250
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2133-2150 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 568937372  2133 RLFCDICDCFDlHDTEDC 2150
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.70e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.70e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.36e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.36e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 5.20e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.44  E-value: 5.20e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372    213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.53e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.53e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1047-1919 3.52e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.52e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1047 QKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLYAQEANA 1118
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1119 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1198
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1199 ELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkkltaenlvlVKDKDDVIQKLQSAYEELV 1278
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1279 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTclTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1358
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQE--IEELLKKLEEAELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1359 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqllhEKESLAASERTLLAEKEELLSENRII 1438
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1439 TEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGD 1511
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1512 LRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTsmIQAKDN 1588
Cdd:TIGR02168  606 DLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1589 lnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSE 1668
Cdd:TIGR02168  678 ---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1669 QLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL 1748
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1749 TERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDK 1821
Cdd:TIGR02168  831 RRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1822 SKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLEDTKQTNAR-----LQNELDTLKENNLK 1887
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKIEDDEEEARrrlkrLENKIKELGPVNLA 990

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568937372  1888 TVEELNKSKELLSVENQKMEEFKKEIETLKQA 1919
Cdd:TIGR02168  991 AIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 634-1432 1.24e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 100.14  E-value: 1.24e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   634 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 710
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   711 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 790
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   791 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 870
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   871 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   944 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 1009
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1010 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1072
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1073 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1129
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1130 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1208
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1209 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1288
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1289 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1368
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372  1369 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1432
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 724-1487 7.88e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.88e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   724 LVEMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKanSEGKLELETLRQQLEGAEKQI 803
Cdd:TIGR02168  181 LERTRENLDRLEDI---LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRL--EELREELEELQEELKEAEEEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   804 KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 883
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   884 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 963
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   964 LTKANENASFLQKSIGEVTLKAEQSQ----QQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSEtKTKH 1039
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAEleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR-LDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1040 EEILQNLQ------KMLADTEDKLKAAQEANRDLMQDMEELKTQADKA--KSLTYLLT----SAKKEIEVMSEELRG--- 1104
Cdd:TIGR02168  495 ERLQENLEgfsegvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAlgGRLQAVVVenlnAAKKAIAFLKQNELGrvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1105 -----LKSEKQLYAQEANALKLEKG--SLLSKLIEVETKITLLQED-------QQKLWSVNETLHLEKER---VSEEKQV 1167
Cdd:TIGR02168  575 flpldSIKGTEIQGNDREILKNIEGflGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAKKLRPGyriVTLDGDL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1168 AEKRY--QQEHRDRESLV----AEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAE 1241
Cdd:TIGR02168  655 VRPGGviTGGSAKTNSSIlerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1242 KEHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQ 1321
Cdd:TIGR02168  735 LARLEAEVEQLEER-----------IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1322 TNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRA 1401
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1402 ITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQ 1481
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963


                   ....*.
gi 568937372  1482 DSLLKE 1487
Cdd:TIGR02168  964 EDDEEE 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 789-1577 1.03e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 1.03e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   789 LETLRQQLEGAEKQIKNLETERNAESS----KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSE 864
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAELRELELAllvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   865 EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLT 944
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   945 KMNDELRLKERSVEELQLKLTKANENASFLQKsigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDL 1024
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1025 KAKYEkassetktKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLtsakkeiEVMSEELRG 1104
Cdd:TIGR02168  439 QAELE--------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-------ERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1105 LKSEKQLYAQEANALKLEKGsLLSKLIEVETKI-----TLLQEDQQKLWSVNETL------HLEKERVSE---------- 1163
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILG-VLSELISVDEGYeaaieAALGGRLQAVVVENLNAakkaiaFLKQNELGRvtflpldsik 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1164 --EKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL-KMHMENDSLEASKVSMQVLIEELRFCKD----------- 1229
Cdd:TIGR02168  583 gtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLgGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvit 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1230 -----KLMAMSEKaRAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMS 1304
Cdd:TIGR02168  663 ggsakTNSSILER-RREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1305 LDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQT 1384
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1385 SNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTL---LAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKIT 1461
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1462 YLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDL--------------RRKYDQEATNRRIVM 1527
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltleeaealenkIEDDEEEARRRLKRL 977

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937372  1528 QEKMKLLG--NIDALkKELQERKKENQELTSSKCDLslllkeaQDAKKNLEK 1577
Cdd:TIGR02168  978 ENKIKELGpvNLAAI-EEYEELKERYDFLTAQKEDL-------TEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 356-1199 3.16e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.16e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   356 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHdqhvLELEAKMDQLRTMVEAADREKVELLNQLEEEKR 435
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----SELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   436 KVEDLQFRVEEESITKGDLEQKSPISEDPENT-QTKLEHARTKELEQSLLFEKTKADKLQRE--LEDTRVATVSEKSRIM 512
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAElEEKLEELKEELESLEAELEELEAELEELEsrLEELEEQLETLRSKVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   513 ELEKDLALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKL-EAIHTDHQGEMTSLKEHFGAREEAFQKEIKALH 591
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLE-----DRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   592 TATEKLSKENESLRSKLDHANKENSDVIALwkskletaiashqQAMEELKVSFSKGIgtdsaefAELKTQIERLRLDYQH 671
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSL-------------ERLQENLEGFSEGV-------KALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   672 EIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVK---------ARLDSAEDQHLVEmeDTLNKLQEAEIKVK 742
Cdd:TIGR02168  525 LSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKqnelgrvtfLPLDSIKGTEIQG--NDREILKNIEGFLG 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   743 ELEVLQAKYTEQSEVIGNFTSQLSAVKekllDLD-ALRKANSEGKLEL-------------------ETLRQQLEGAEKQ 802
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVD----DLDnALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   803 IKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ 882
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   883 KEEQFNVLSSELEKLRENLTDMEAKfkekddredqlvkaKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQL 962
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAE--------------IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   963 KLTKANENASFLQKSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDLKAKYEKASSEtKTKHEEI 1042
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIES---------------LAAEIEELEELIEELESELEALLNE-RASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1043 LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKsltylltSAKKEIEVMSEELRG-LKSEKQLYAQEANALKL 1121
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-------LRLEGLEVRIDNLQErLSEEYSLTLEEAEALEN 961

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372  1122 EKGSLLSKLievETKITLLQEDQQKLWSVNETlhlekerVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEE 1199
Cdd:TIGR02168  962 KIEDDEEEA---RRRLKRLENKIKELGPVNLA-------AIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 652-1322 3.24e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 3.24e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   652 SAEFAELKTQIERLRLdYQHEIESLQSKQDSERSAHAKEMETMQAKLMkIIKEKEDSLEAVKARLDSAEDQHLVEMEDTL 731
Cdd:TIGR02168  259 TAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   732 NKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDA----LRKANSEGKLELETLRQQLEGAEKQIKNLE 807
Cdd:TIGR02168  337 EELAELE---EKLEELKEELESLEAELEELEAELEELESRLEELEEqletLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   808 TERNAESSKANSITKELQEKELVLtgLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 887
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   888 NVLSSELEKLRENLTDMEAKFKEKDDRED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSV 957
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   958 EELQLKLTKANENAsfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE-LEKKMETSYNQCQDLKAKY-------- 1028
Cdd:TIGR02168  572 RVTFLPLDSIKGTE--IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlGGVLVVDDLDNALELAKKLrpgyrivt 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1029 -----------------EKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAK-------- 1082
Cdd:TIGR02168  650 ldgdlvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELeelsrqis 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1083 SLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVS 1162
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1163 EEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELrfckdklmamsekaRAEK 1242
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL--------------ESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1243 EHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQT 1322
Cdd:TIGR02168  876 EALLNERASLEEA-----------LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 352-993 6.36e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 6.36e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   352 LQEALKEKQQHIEQLLAERDLERAEVAKATshvgEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADrekvellNQLE 431
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLN-------NEIE 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   432 EEKRKVEDLQFRVEEESITKGDLEQkspisedpentqtKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRI 511
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLK-------------KLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   512 MELEKDLALRAQEVAELRRRLESSKppgdvdmslSLLQEISALQEKLEAIhTDHQGEMTSLKEHFGAREEAFQKEIKALH 591
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLE---------RLQENLEGFSEGVKAL-LKNQSGLSGILGVLSELISVDEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   592 TATEK-----LSKENESLRSKLDHAnKENSDVIALWkSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERL- 665
Cdd:TIGR02168  541 AALGGrlqavVVENLNAAKKAIAFL-KQNELGRVTF-LPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAl 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   666 --RLDYQHEIESLQSKQDSERSAHAKEMetmqaklmkIIKEKEDSLEAVKARLDSAEDQHLV------EMEDTLNKLQEA 737
Cdd:TIGR02168  619 syLLGGVLVVDDLDNALELAKKLRPGYR---------IVTLDGDLVRPGGVITGGSAKTNSSilerrrEIEELEEKIEEL 689

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   738 EIKVKELEV-LQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSK 816
Cdd:TIGR02168  690 EEKIAELEKaLAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   817 ANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEK 896
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   897 LRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQK 976
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL 929

                          650
                   ....*....|....*..
gi 568937372   977 SIGEVTLKAEQSQQQAA 993
Cdd:TIGR02168  930 RLEGLEVRIDNLQERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 709-1291 1.94e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.94e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  709 LEAVKARLDSAEDqHLVEMEDTLNKLQ-EAEIKVK------ELEVLQAKYteqsevignftsQLSAVKEKLLDLDALRKA 781
Cdd:COG1196   181 LEATEENLERLED-ILGELERQLEPLErQAEKAERyrelkeELKELEAEL------------LLLKLRELEAELEELEAE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  782 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANS-------ITKELQEKELVLTGLQDSLNQVNQVKETLEKELQT 854
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyeLLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  855 LKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 934
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  935 MSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQ--SQQQAARKHEEEKKELEEKLLELEK 1012
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELA 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1013 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQ----KMLADTEDKLKAAQEA------NRDLMQDMEELKTQADKAK 1082
Cdd:COG1196   488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLK 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1083 SLT------YLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1156
Cdd:COG1196   568 AAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1157 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckDKLMAMSE 1236
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER---LEEELEEE 724

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568937372 1237 KARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1291
Cdd:COG1196   725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 513-1307 2.06e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 2.06e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   513 ELEKDL------ALRAQEVAELRRRLEsskppgDVDMSLSLLqEISALQEKLEAIhtdhQGEMTSLKEhfgaREEAFQKE 586
Cdd:TIGR02168  197 ELERQLkslerqAEKAERYKELKAELR------ELELALLVL-RLEELREELEEL----QEELKEAEE----ELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   587 IKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGigtdSAEFAELKTQIERLR 666
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   667 LDY---QHEIESLQSKQDSERSAHAKEMETMQAkLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEIKVKE 743
Cdd:TIGR02168  337 EELaelEEKLEELKEELESLEAELEELEAELEE-LESRLEELEEQLETLRSKVAQLELQ----IASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   744 LEVLQAKYTEQSEVIGNfTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKE 823
Cdd:TIGR02168  412 LEDRRERLQQEIEELLK-KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   824 ---LQEKELVLTGLQDSLNQVNQVKETLEKELQTLKE--KFASTSEEAVSA--QTRMQD-TVNKLHQKEEQFNVLSSELE 895
Cdd:TIGR02168  491 ldsLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAAIEAalGGRLQAvVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   896 --------------KLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMkmSG----DNSSQLTKMNDELRLKERSV 957
Cdd:TIGR02168  571 grvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLL--GGvlvvDDLDNALELAKKLRPGYRIV 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   958 eelqlklTKANE--NASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSET 1035
Cdd:TIGR02168  649 -------TLDGDlvRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1036 KTKHEEIlQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQadkaksltylLTSAKKEIEVMSEELRGLKSEKQLYAQE 1115
Cdd:TIGR02168  722 EELSRQI-SALRKDLARLEAEVEQLEERIAQLSKELTELEAE----------IEELEERLEEAEEELAEAEAEIEELEAQ 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1116 ANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINA 1195
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1196 AQEELlkmhmenDSLEASKVSMQVLIEELRFCKDKLMA----MSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQ 1271
Cdd:TIGR02168  871 LESEL-------EALLNERASLEEALALLRSELEELSEelreLESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 568937372  1272 SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDN 1307
Cdd:TIGR02168  944 RLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 351-969 2.42e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.42e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALArdghDQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL----EQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   431 EEEKRKVEDLQFRVEEesiTKGDLEQKSPISEDPENTQTKLEhARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSR 510
Cdd:TIGR02168  333 DELAEELAELEEKLEE---LKEELESLEAELEELEAELEELE-SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   511 IMELEKDLALRAQEVAELRRRLESSkppgDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQK----- 585
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEA----ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAaerel 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   586 -----EIKALHTATEKLSKENESLRSKLDHANKENSDVIAL---------WKSKLETAIASHQQAME-------ELKVSF 644
Cdd:TIGR02168  485 aqlqaRLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLselisvdegYEAAIEAALGGRLQAVVvenlnaaKKAIAF 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   645 SKGIGTDSAEFAELK----TQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKI-IKEKEDSLEAVKARLDSA 719
Cdd:TIGR02168  565 LKQNELGRVTFLPLDsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlVVDDLDNALELAKKLRPG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   720 E-----DQHLV----------------------EMEDTLNKLQEAEIKVKELEV-LQAKYTEQSEVIGNFTSQLSAVKEK 771
Cdd:TIGR02168  645 YrivtlDGDLVrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKaLAELRKELEELEEELEQLRKELEEL 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   772 LLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKET---- 847
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlrea 804

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   848 ---LEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEK 924
Cdd:TIGR02168  805 ldeLRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 568937372   925 LENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANE 969
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL 929
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-932 6.23e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 6.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDG---HDQHVLELEAKMDQLRTMVEAADREKVELL 427
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELE 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  428 NQLEEEKRKVEDLQFRVEEEsitKGDLEQKSPISEDPENTQTKLEHARtKELEQSLLFEKTKADKLQRELEDTRVATVSE 507
Cdd:COG1196   323 EELAELEEELEELEEELEEL---EEELEEAEEELEEAEAELAEAEEAL-LEAEAELAEAEEELEELAEELLEALRAAAEL 398

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  508 KSRIMELEKDLALRAQEVAELRRRLESSKppGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEI 587
Cdd:COG1196   399 AAQLEELEEAEEALLERLERLEEELEELE--EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  588 KALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAM-EELKVSFSKGIGTDSAEFAELKTQIERLR 666
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVaVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  667 LDYQHEIESLQSKQ---------DSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEA 737
Cdd:COG1196   557 EVAAAAIEYLKAAKagratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  738 EIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSka 817
Cdd:COG1196   637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-- 714

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  818 nsitKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTrMQDTVNKLHQKEEQF---NVLS-SE 893
Cdd:COG1196   715 ----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE-LERELERLEREIEALgpvNLLAiEE 789

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 568937372  894 LEKLRENLTDMEAKfkekddREDqLVKAKEKLENDIAEI 932
Cdd:COG1196   790 YEELEERYDFLSEQ------RED-LEEARETLEEAIEEI 821
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1052-1663 8.81e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 8.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1052 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1122
Cdd:COG1196   176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1123 KGSLLSKLIEVETKITLLQEDQQKLwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1202
Cdd:COG1196   255 LEELEAELAELEAELEELRLELEEL-------ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1203 MHMENDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQK 1282
Cdd:COG1196   328 LEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1283 ALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1362
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1363 TQLDcASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEK- 1441
Cdd:COG1196   484 EELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAa 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1442 --LSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADResSIKTIGDLRRKYDQE 1519
Cdd:COG1196   563 ieYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1520 ATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELktcccE 1599
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-----E 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372 1600 KNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRL 1663
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-905 1.62e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 76.70  E-value: 1.62e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   425 ELLNQLEEE---------KRKVEDLQFrvEEESITKGDLEQKSPISEDPENTQTKLEHARTKELEQSLLFEKTKADKLQR 495
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQF--SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   496 ELEDTRVatvsEKSRIMELEKDLALRAQ------------------EVAELRRRLESSKppgdvDMSLSLLQEISALQEK 557
Cdd:pfam15921  420 ELDDRNM----EVQRLEALLKAMKSECQgqmerqmaaiqgknesleKVSSLTAQLESTK-----EMLRKVVEELTAKKMT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   558 LEAIHTDHQGEMTSLKEHFGAREeAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIAS 632
Cdd:pfam15921  491 LESSERTVSDLTASLQEKERAIE-ATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILRQ 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   633 HQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAV 712
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAV 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   713 KaRLDSAEDQHLVEMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLsavkeklldldalrkansegKLELETL 792
Cdd:pfam15921  649 K-DIKQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKSA 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   793 RQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTR 872
Cdd:pfam15921  705 QSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE 784

                          570       580       590
                   ....*....|....*....|....*....|...
gi 568937372   873 MQDTVNKLHqkeeqfnVLSSELEKLRENLTDME 905
Cdd:pfam15921  785 KNKMAGELE-------VLRSQERRLKEKVANME 810
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1288-1919 3.71e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1288 IEDLTTEKksaaEKQMSldntclTLKAERENLLQtNRDLQFEKDTLRQgqEKLSASLEATLQVKQLLSTEAETLRTQLDC 1367
Cdd:COG1196   191 LEDILGEL----ERQLE------PLERQAEKAER-YRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1368 ASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSE 1447
Cdd:COG1196   258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1448 EVARLEmglnekityltSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVM 1527
Cdd:COG1196   338 ELEELE-----------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1528 QEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmllrdg 1607
Cdd:COG1196   407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL------------ 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1608 lnLQEECQKLNEEIREIQQTLILEKEARAKESETSlyennKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQK 1687
Cdd:COG1196   475 --LEAALAELLEELAEAAARLLLLLEAEADYEGFL-----EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1688 VEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKRE 1767
Cdd:COG1196   548 LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1768 MMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1847
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372 1848 QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELnkskELLSVENQKMEEFKKEIETLKQA 1919
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1414-2077 5.45e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 5.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1414 KESLAASERTLLA----EKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKS 1489
Cdd:TIGR02168  219 KAELRELELALLVlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1490 ALELQNGDLLADRESSIKTIGDLRRkYDQEATNRRIVMQEKMKLLGN-IDALKKELQERKKENQELTSSKCDLSLLLKEA 1568
Cdd:TIGR02168  299 RLEQQKQILRERLANLERQLEELEA-QLEELESKLDELAEELAELEEkLEELKEELESLEAELEELEAELEELESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1569 QDAKKNLEKEHTSMIQAKDNLNAELKtccceknmllrdglNLQEECQKLNEEIREIQQtlilekEARAKESETSLYENNK 1648
Cdd:TIGR02168  378 EEQLETLRSKVAQLELQIASLNNEIE--------------RLEARLERLEDRRERLQQ------EIEELLKKLEEAELKE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1649 LHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAA---NIETLKSDFAALSKSKLE 1725
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqeNLEGFSEGVKALLKNQSG 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1726 LQELHSCLTKILD---DLRLNHEVALTERAEvlqdnkNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNsh 1802
Cdd:TIGR02168  518 LSGILGVLSELISvdeGYEAAIEAALGGRLQ------AVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGN-- 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1803 iSANLLESQSENRTLRKDKSKLTLKIRE-LETLHSFTA-AQTAEDAMQIMEQMTKEktETLASLEDTKQTNARLQNELDT 1880
Cdd:TIGR02168  590 -DREILKNIEGFLGVAKDLVKFDPKLRKaLSYLLGGVLvVDDLDNALELAKKLRPG--YRIVTLDGDLVRPGGVITGGSA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1881 LKENNLktveeLNKSKELLSVEnQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSV 1960
Cdd:TIGR02168  667 KTNSSI-----LERRREIEELE-EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1961 LNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAK----SLHSVVQTLESDKV 2036
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRealdELRAELTLLNEEAA 820

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 568937372  2037 KLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQ 2077
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 659-1364 5.82e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.77  E-value: 5.82e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   659 KTQIERLRLDYQHEIESLQSKQDSERSAHAKE-------METMQAKLMKIIKEKeDSLEAVKARLDSAEDQHLVEMEDTL 731
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQkfylrqsVIDLQTKLQEMQMER-DAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   732 NKLQEAE-IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDAL--RKANSEGKLELETLRQQLEGAEKQIKNLET 808
Cdd:pfam15921  152 HELEAAKcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   809 ERNAESSKANSITKELQ--------EKELVLTGLQDslnQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM----QDT 876
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEalksesqnKIELLLQQHQD---RIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQA 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   877 VNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK-DDREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDEL-- 950
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLhk 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   951 RLKERSVEELQLKLTKANENASFLqkSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDlKAKYEK 1030
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQR---------------LEALLKAMKSECQG-QMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1031 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1110
Cdd:pfam15921  451 AAIQGKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1111 LYAQEANALKLEKGSLLSKLIEVET-KITLLQEDQqklwsVNETLHLEKERVSEekqvaekRYQQEHRDRESLVAEREKL 1189
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDK-----VIEILRQQIENMTQ-------LVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1190 LKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARAEKEhlegqVKKLTAENLVLVKDKDDVIQ 1268
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAVKD-----IKQERDQLLNEVKTSRNELN 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1269 KLQSAYEELVKDQKALVQEIEDLTTE-KKSAAEKQMSLDNTCLTLK---------------------AERENLLQTNRDL 1326
Cdd:pfam15921  671 SLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmqkqitAKRGQIDALQSKI 750

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 568937372  1327 QF----------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1364
Cdd:pfam15921  751 QFleeamtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1536-2114 1.73e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.17  E-value: 1.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1536 NIDALKKELQERKKENQELTSSKCDLslllkeaQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRdglnLQEECQ 1615
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENI-------EELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1616 KLNEEIREIQ-QTLILEKEARAKESETSLYEN--NKLHGRVVLLEEEIQRLRVCsEQLQTENFTLTQEKTNSEQKVEEII 1692
Cdd:PRK03918  235 ELKEEIEELEkELESLEGSKRKLEEKIRELEEriEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1693 KEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEV-ALTERAEVLQDN-KNLLAEKREMML 1770
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRlTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1771 rnEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLEsqsenrtLRKDKSKLTLKIRELETLH--SFTAAQTAEdamq 1848
Cdd:PRK03918  394 --EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHrkELLEEYTAE---- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1849 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE--NNLKTVEELNKSKELLSVEN-QKMEEFKKEIETLKQAAAQKSQ 1925
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1926 QLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLL--------EMKKRESEFR---------KDADEEKASLQK 1988
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEelgfesveELEERLKELEpfyneylelKDAEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1989 SISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQ 2066
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 568937372 2067 AEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2114
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1359-2081 2.02e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 2.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1359 ETLRTQLDCASKALR-KAELDMRQLQTSNSSLTKLLEEIKTCRAITDseciqllhEKESLAASERTLLAEKEELLSENRI 1437
Cdd:TIGR02168  203 KSLERQAEKAERYKElKAELRELELALLVLRLEELREELEELQEELK--------EAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1438 ITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYD 1517
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1518 ---QEATNRRIVMQEkmkLLGNIDALKKELQERKKE----NQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNL- 1589
Cdd:TIGR02168  355 sleAELEELEAELEE---LESRLEELEEQLETLRSKvaqlELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLe 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1590 NAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQ 1669
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1670 LQTEN-----FTLTQEKTNSEQKVEEIIkEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNH 1744
Cdd:TIGR02168  512 LKNQSglsgiLGVLSELISVDEGYEAAI-EAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1745 EVALTERAEVLQDNKNLLAEKREMM---------------LRNEEALKEKEKLEESYFILQKEI----SQLAQTNSHISA 1805
Cdd:TIGR02168  591 REILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddLDNALELAKKLRPGYRIVTLDGDLvrpgGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1806 NLLESQSENRTLRKDKSKLTLKIRELET-----LHSFTAAQTA-EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1879
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKalaelRKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1880 TLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVtsHQKLEEERS 1959
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA--ANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1960 VLNNqlLEMKKRESEfrkDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLhsvVQTLESDKVKLE 2039
Cdd:TIGR02168  829 LERR--IAATERRLE---DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA---LALLRSELEELS 900

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 568937372  2040 LKVKNLELQLKENKRQLSSSsgnTDAQAEEDERAQESQQMID 2081
Cdd:TIGR02168  901 EELRELESKRSELRRELEEL---REKLAQLELRLEGLEVRID 939
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 3.12e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 72.03  E-value: 3.12e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937372  211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1093-1917 4.05e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 4.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1093 KEIEVMSEELRGLKSEK--QLYAQEANALKLEK-GSLLSKLIEVETKITLlqedqqklwsvNETLHLEKERVSEEKQVAE 1169
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKrqQLERLRREREKAERyQALLKEKREYEGYELL-----------KEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1170 KRYQQEHR-----DRESLVAEREKLLKEINA-----AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKAR 1239
Cdd:TIGR02169  249 LEEELEKLteeisELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1240 AEKEHLEGQVKKLTAENLVLVKDKDdviqKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1319
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRD----KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1320 LQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTC 1399
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1400 RAITDSECIQLLHEKESLAASERTLLAEKEELLSENR----IITEKLSKQSEEVARLEMGLNEKITYLTSEKE-VACQKV 1474
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDaVAKEAI 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1475 AKLKKQQDS----LLKEKSALELQNGDLLAdRESSIKTIGDLRRKYDQEATNRRIVMQEKMkLLGNIDALKKELQERK-- 1548
Cdd:TIGR02169  565 ELLKRRKAGratfLPLNKMRDERRDLSILS-EDGVIGFAVDLVEFDPKYEPAFKYVFGDTL-VVEDIEAARRLMGKYRmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1549 ---KENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmllrdglnlqeecqkLNEEIREIQ 1625
Cdd:TIGR02169  643 tleGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSS---------------------LQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1626 QtLILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQL 1705
Cdd:TIGR02169  702 N-RLDELSQELSDASRKIGEIEK---EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1706 AANIETLK-----SDFAALSKSKLELQELHSCLTKILDDL------RLNHEVALTERAEVLQDNKNLLAEKREMMLRNEE 1774
Cdd:TIGR02169  778 EEALNDLEarlshSRIPEIQAELSKLEEEVSRIEARLREIeqklnrLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1775 ALK-EKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME-- 1851
Cdd:TIGR02169  858 NLNgKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEie 937

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372  1852 ---QMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEE----------LNKSKELLSVENQKMEEFKKEIETLK 1917
Cdd:TIGR02169  938 dpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEyeevlkrldeLKEKRAKLEEERKAILERIEEYEKKK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 779-1453 4.11e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 4.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  779 RKANSEGKLE--------LETLRQQLEgaeKQIKNLETERN-AEssKANSITKELQEKELVLTGLQDslnqvnqvkETLE 849
Cdd:COG1196   173 RKEEAERKLEateenlerLEDILGELE---RQLEPLERQAEkAE--RYRELKEELKELEAELLLLKL---------RELE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  850 KELQTLKEKFASTSEEAVSAQTRMQDtvnklhqkeeqfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDI 929
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAE--------------LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  930 AEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 1009
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1010 LEKKME--TSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1087
Cdd:COG1196   385 AEELLEalRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1088 LTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVetKITLLQEDQQKLW-SVNETLHLEKERVSEEKQ 1166
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAgAVAVLIGVEAAYEAALEA 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1167 VAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckdklmamsekaraekehle 1246
Cdd:COG1196   543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV--------------------- 601

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1247 gqvkkltaenlvlvkdkdDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDL 1326
Cdd:COG1196   602 ------------------DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1327 QFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEiktcraitdse 1406
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA----------- 732

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 568937372 1407 ciqllhEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLE 1453
Cdd:COG1196   733 ------EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 725-1622 4.44e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 4.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   725 VEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEvignftsQLSAVKEKLLDLDALRKanSEGKLELETLRQQLEGAEKQIK 804
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLE-------RLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   805 NLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN-QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 883
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   884 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimkmsgdnssqltkmnDELRLKERSVEELQLK 963
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK---------------------EELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   964 LTKANENASFLQKSIGEVTLKAEQSQQQAARKheeekkeleekllelekkmetsynqcqdlkakyekasSETKTKHEEIL 1043
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRL-------------------------------------QEELQRLSEEL 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1044 QNLQKMLADTEDKLKAAQEANRDLmqdMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEK 1123
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDK---ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1124 GSLLSKLIEVETKITLLQEDQQKLW-SVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1202
Cdd:TIGR02169  500 RASEERVRGGRAVEEVLKASIQGVHgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLP 579

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1203 MH-MENDSLEASKVSMQVLIE---ELRFCKDK-------------LMAMSEKARAekehLEGQVKKLTAENLVLvkDKDD 1265
Cdd:TIGR02169  580 LNkMRDERRDLSILSEDGVIGfavDLVEFDPKyepafkyvfgdtlVVEDIEAARR----LMGKYRMVTLEGELF--EKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1266 VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaekqmsldntcltLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLE 1345
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1346 ATLQVKQLLSTEAETLRtqldcaskalRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLL 1425
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK----------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1426 AEKEellsenRIITEKLSKQSEEVARLEMGLNE---KITYLTSEKEVACQKVAKLKKQQDsllkeksALELQNGDLLADR 1502
Cdd:TIGR02169  790 HSRI------PEIQAELSKLEEEVSRIEARLREieqKLNRLTLEKEYLEKEIQELQEQRI-------DLKEQIKSIEKEI 856

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1503 ESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM 1582
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 568937372  1583 IQAKDNLNAElktccCEKNMLLRDglnLQEECQKLNEEIR 1622
Cdd:TIGR02169  937 EDPKGEDEEI-----PEEELSLED---VQAELQRVEEEIR 968
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 416-1206 5.92e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 5.92e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   416 VEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQK--------SPISEDPENT-QTKLE--HARTKELEQSLL 484
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLleelnkkiKDLGEEEQLRvKEKIGelEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   485 FEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdmslsllQEISALQEKLEAIHTD 564
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK------------EELEDLRAELEEVDKE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   565 HQgemTSLKEHFGARE--EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDV---IALWKSKLETAIASHQQAMEE 639
Cdd:TIGR02169  380 FA---ETRDELKDYREklEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIeakINELEEEKEDKALEIKKQEWK 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   640 LKvSFSKGIGTDSAEFAELKTQIERLrldyQHEIESLQSKQDsERSAHAKEMETMQAKLMKIIKEKEDSLEAVK---ARL 716
Cdd:TIGR02169  457 LE-QLAADLSKYEQELYDLKEEYDRV----EKELSKLQRELA-EAEAQARASEERVRGGRAVEEVLKASIQGVHgtvAQL 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   717 DSAEDQHLVEMEDTL-NKLQEAeikVKELEVLQAKYTE--QSEVIGNFTS-QLSAVKEKLLDLDALRKANSEG-KLELET 791
Cdd:TIGR02169  531 GSVGERYATAIEVAAgNRLNNV---VVEDDAVAKEAIEllKRRKAGRATFlPLNKMRDERRDLSILSEDGVIGfAVDLVE 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   792 LRQQLEGAEKQI-------KNLETERNAESS-KANSITKELQEKELVLTG--------------LQDSLNQVNQVKETLE 849
Cdd:TIGR02169  608 FDPKYEPAFKYVfgdtlvvEDIEAARRLMGKyRMVTLEGELFEKSGAMTGgsraprggilfsrsEPAELQRLRERLEGLK 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   850 KELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDdredqlvkakEKLENDI 929
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE----------QEIENVK 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   930 AEimkmsgdnssqLTKMNDELRLKERSVEELQLKLT--KANENASFLQKSIGEVT-LKAEQSQQQAARKH-EEEKKELEE 1005
Cdd:TIGR02169  758 SE-----------LKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSkLEEEVSRIEARLREiEQKLNRLTL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1006 KLLELEKKMETSYNQCQDLKAKyekassetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKslt 1085
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQ--------IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE--- 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1086 ylltsakKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVnETLHLEKERVSEEK 1165
Cdd:TIGR02169  896 -------AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEI 967

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568937372  1166 QV--------------AEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHME 1206
Cdd:TIGR02169  968 RAlepvnmlaiqeyeeVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-932 6.77e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 6.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  351 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELALAR---DGHDQHVLELEAKMDQLRTMVEAADREKVELL 427
Cdd:COG1196   217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELEELEaelAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  428 NQLEEEKRKVEDLQFRVEEESITKGDLEQkspiSEDPENTQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSE 507
Cdd:COG1196   295 AELARLEQDIARLEERRRELEERLEELEE----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  508 KSRIMELEKDLALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEI 587
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELA-----AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  588 KALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIAS----HQQAMEELKVSFSKGIGtdsaefaeLKTQIE 663
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAarllLLLEAEADYEGFLEGVK--------AALLLA 517

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  664 RLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDS-AEDQHLVEMEDTLNKLQEAEIKVK 742
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGrATFLPLDKIRARAALAAALARGAI 597

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  743 ELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITK 822
Cdd:COG1196   598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  823 ELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQtrmqdtvnKLHQKEEQFNVLSSELEKLRENLT 902
Cdd:COG1196   678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA--------LEEQLEAEREELLEELLEEEELLE 749

                         570       580       590
                  ....*....|....*....|....*....|
gi 568937372  903 DMEAKFKEKDDREDQLVKAKEKLENDIAEI 932
Cdd:COG1196   750 EEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 623-1194 1.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 1.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  623 KSKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKlmKII 702
Cdd:COG1196   241 LEELEAELEELEAELEELE-----------AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI--ARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  703 KEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELE-VLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKA 781
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEeELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  782 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFAS 861
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  862 TSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDRE-----DQLVKAKEKLENDIAEIMKMS 936
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavAVLIGVEAAYEAALEAALAAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  937 G-----DNSSQLTKMNDEL-RLKERSVEELQL---KLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKL 1007
Cdd:COG1196   548 LqnivvEDDEVAAAAIEYLkAAKAGRATFLPLdkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1008 LELEKKMETSYN------------QCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELK 1075
Cdd:COG1196   628 VAARLEAALRRAvtlagrlrevtlEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1076 TQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNetlh 1155
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVN---- 783

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 568937372 1156 lekERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEIN 1194
Cdd:COG1196   784 ---LLAIEEYEELEERYDFLSEQREDLEEARETLEEAIE 819
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 406-1164 2.63e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.38  E-value: 2.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   406 EAKMDQLRTMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitKGDLEQKSPISEDPENTQTKLEHARTKelEQSLLF 485
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN--ELHEKQKFYLRQSVIDLQTKLQEMQME--RDAMAD 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   486 EKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQ-EVAELRRRLESSKppgdvdmslSLLQEISALQEKLEAIHTD 564
Cdd:pfam15921  132 IRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNtQIEQLRKMMLSHE---------GVLQEIRSILVDFEEASGK 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   565 HQGEMTSLKE-HFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENsdvialwKSKLETAIASHQQAMEELKVS 643
Cdd:pfam15921  203 KIYEHDSMSTmHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSES-------QNKIELLLQQHQDRIEQLISE 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   644 FSKGIGTDSAEFAELKTQIERLrldyQHEIESLQSKQDSERSAHakemetmqaklMKIIKEKEDSLEAVKARLDSAEDQH 723
Cdd:pfam15921  276 HEVEITGLTEKASSARSQANSI----QSQLEIIQEQARNQNSMY-----------MRQLSDLESTVSQLRSELREAKRMY 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   724 LVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSeviGNFTSQLSAV------KEKLLDLDA-----LRKANSEGKLELETL 792
Cdd:pfam15921  341 EDKIEELEKQLVLANSELTEARTERDQFSQES---GNLDDQLQKLladlhkREKELSLEKeqnkrLWDRDTGNSITIDHL 417

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   793 RQQLEGAEKQIKNLETERNAESSKANSitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLK---EKFASTSEEAVSA 869
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQG---QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRkvvEELTAKKMTLESS 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   870 QTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLE---------NDIAEIMKMSGDNS 940
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmaekDKVIEILRQQIENM 574

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   941 SQLT-------------KMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQ-QAARKHEEEKKELEEK 1006
Cdd:pfam15921  575 TQLVgqhgrtagamqveKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvNAGSERLRAVKDIKQE 654

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1007 LLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMladtEDKLKAAQ---EANRDLMQDMEELKTQADK-AK 1082
Cdd:pfam15921  655 RDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKL----KMQLKSAQselEQTRNTLKSMEGSDGHAMKvAM 730

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1083 SLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETkitllqeDQQKLWSVNETLHLEKERVS 1162
Cdd:pfam15921  731 GMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAT-------EKNKMAGELEVLRSQERRLK 803


                   ..
gi 568937372  1163 EE 1164
Cdd:pfam15921  804 EK 805
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 925-1834 3.26e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 3.26e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   925 LENDIAEIMKMSG--------------DNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSigevTLKAEQSQQ 990
Cdd:TIGR02169  140 LQGDVTDFISMSPverrkiideiagvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERYQA 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   991 QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKakyekassETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQD 1070
Cdd:TIGR02169  216 LLKEKREYEGYELLKEKEALERQKEAIERQLASLE--------EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1071 mEELKTQADKAkSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSV 1150
Cdd:TIGR02169  288 -EQLRVKEKIG-ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1151 NETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASkvsmqvlIEELRFCKDK 1230
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA-------IAGIEAKINE 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1231 LMAMSEKARAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCL 1310
Cdd:TIGR02169  439 LEEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1311 TLKAERENLLQTNRDL-QFEKDTLRQGQEKLSASLEATLQVKQLLSTEAetlrTQLDCASKALRKAELDMRQLQTSNSSL 1389
Cdd:TIGR02169  515 VLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDAVAKEA----IELLKRRKAGRATFLPLNKMRDERRDL 590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1390 TKLLEEIKTCRAITDSECIQlLHEKESLAASERTLLAEKEE----LLSENRIIT---EKLSKQSEEV--ARLEMGLNEKI 1460
Cdd:TIGR02169  591 SILSEDGVIGFAVDLVEFDP-KYEPAFKYVFGDTLVVEDIEaarrLMGKYRMVTlegELFEKSGAMTggSRAPRGGILFS 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1461 TYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDAL 1540
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1541 KKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKehtsmiqakdnlnaelktccceknMLLRDGL-NLQEECQKLNE 1619
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA------------------------RLSHSRIpEIQAELSKLEE 805

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1620 EIREIqqtlilekEARAKESETSLyenNKLHGRVVLLEEEIQrlrvcseQLQTENFTLTQEKTNSEQKVEEIIKEKELLS 1699
Cdd:TIGR02169  806 EVSRI--------EARLREIEQKL---NRLTLEKEYLEKEIQ-------ELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1700 AETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVA------LTERAEVLQDNKNLLAEKREMMLRNE 1773
Cdd:TIGR02169  868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKrkrlseLKAKLEALEEELSEIEDPKGEDEEIP 947

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372  1774 EALKEKEKLEESYFILQKEISQLAQTN-------SHISANLLESQSENRTLRKDKSKLTLKIRELETL 1834
Cdd:TIGR02169  948 EEELSLEDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 352-1198 4.53e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 4.53e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   352 LQEALKEKQQHIEQLLAERD--------LERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRTMVEAADREK 423
Cdd:TIGR02169  189 LDLIIDEKRQQLERLRREREkaeryqalLKEKREYEGYELLKEKEALERQKEAIERQ-LASLEEELEKLTEEISELEKRL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   424 VELLNQLEEEKRKVEDL----QFRVEEE-SITKGDLEQKSPISEDPENTQTKLEhARTKELEQSLLFEKTKADKLQRELE 498
Cdd:TIGR02169  268 EEIEQLLEELNKKIKDLgeeeQLRVKEKiGELEAEIASLERSIAEKERELEDAE-ERLAKLEAEIDKLLAEIEELEREIE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   499 DTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEaihtDHQGEMTSLKEhfga 578
Cdd:TIGR02169  347 EERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR-----DELKDYREKLEKLKREIN----ELKRELDRLQE---- 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   579 reeafqkEIKALHTATEKLSKENESLRSKldhankensdvIALWKSKLETAIASHQQAMEELKvSFSKGIGTDSAEFAEL 658
Cdd:TIGR02169  414 -------ELQRLSEELADLNAAIAGIEAK-----------INELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQELYDL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   659 KTQIERLrldyQHEIESLQSKQDsERSAHAKEMETMQAKLMKIIKEKEDSLEAVK---ARLDSAEDQHLVEMEDTL-NKL 734
Cdd:TIGR02169  475 KEEYDRV----EKELSKLQRELA-EAEAQARASEERVRGGRAVEEVLKASIQGVHgtvAQLGSVGERYATAIEVAAgNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   735 QEAeikVKELEVLQAKYTE--QSEVIGNFTS-QLSAVKEKLLDLDALRKANSEG-KLELETLRQQLEGAEKQI------- 803
Cdd:TIGR02169  550 NNV---VVEDDAVAKEAIEllKRRKAGRATFlPLNKMRDERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVfgdtlvv 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   804 KNLETERNAESS-KANSITKELQEKELVLTG--------------LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVS 868
Cdd:TIGR02169  627 EDIEAARRLMGKyRMVTLEGELFEKSGAMTGgsraprggilfsrsEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   869 AQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDdredqlvkakEKLENDIAEimkmsgdnssqLTKMND 948
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE----------QEIENVKSE-----------LKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   949 ELRLKERSVEELQLKLT--KANENASFLQKSIGEVT-LKAEQSQQQAARKH-EEEKKELEEKLLELEKKMETSYNQCQDL 1024
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSkLEEEVSRIEARLREiEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1025 KAKyekassetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKaksltylltsAKKEIEVMSEELRG 1104
Cdd:TIGR02169  846 KEQ--------IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE----------LEAQLRELERKIEE 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1105 LKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVnETLHLEKERVSEEKQ-------VAEKRYQQEHR 1177
Cdd:TIGR02169  908 LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRalepvnmLAIQEYEEVLK 986

                          890       900
                   ....*....|....*....|.
gi 568937372  1178 DRESLVAEREKLLKEINAAQE 1198
Cdd:TIGR02169  987 RLDELKEKRAKLEEERKAILE 1007
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
340-934 4.61e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 4.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSPISEDPENTQTKLehartKELEQSLLFEKTKADKLQRELED 499
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-----REIEKRLSRLEEEINGIEERIKE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  500 TRvatvSEKSRIMELEKdlalraqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEaihtdhqgemtSLKEHFGAR 579
Cdd:PRK03918  333 LE----EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  580 E-EAFQKEIKALHTATEKLSKENESLRSKldhankensdvialwKSKLETAIASHQQAMEELKVsfskgigtdsaefAEL 658
Cdd:PRK03918  385 TpEKLEKELEELEKAKEEIEEEISKITAR---------------IGELKKEIKELKKAIEELKK-------------AKG 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  659 KTQIERLRLDYQHEIEsLQSKQDSERSAHAKEMETMQAKLMKIIKEKedsleaVKARLDSAEDQHLVEMEDTLNKLQEAE 738
Cdd:PRK03918  437 KCPVCGRELTEEHRKE-LLEEYTAELKRIEKELKEIEEKERKLRKEL------RELEKVLKKESELIKLKELAEQLKELE 509

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  739 IKVKE--LEVLQAKYTEQSEV---IGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAE 813
Cdd:PRK03918  510 EKLKKynLEELEKKAEEYEKLkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEE 589

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  814 SSKANSITKELQEKELVLTGLQDSLnqvnqvkETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNV---- 889
Cdd:PRK03918  590 LEERLKELEPFYNEYLELKDAEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeye 662

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 568937372  890 -LSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 934
Cdd:PRK03918  663 eLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 9.56e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.02  E-value: 9.56e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1331-2097 1.17e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1331 DTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdcaSKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQL 1410
Cdd:TIGR02169  194 DEKRQQLERLRREREKAERYQALLKEKREYEGYEL---LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1411 LHEKESLAASERTLLAEkeellsENRIITEKLSKQSEEVARLEMGLNEKitylTSEKEVACQKVAKLKKQQDSLLKEKSA 1490
Cdd:TIGR02169  271 EQLLEELNKKIKDLGEE------EQLRVKEKIGELEAEIASLERSIAEK----ERELEDAEERLAKLEAEIDKLLAEIEE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1491 LELQNGDLLADRESSIKTIGDLRRKYD-------QEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSL 1563
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELEdlraeleEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1564 LLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDG-------LNLQEECQKLNEEIREIQQTLIlEKEARA 1636
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLskyeqelYDLKEEYDRVEKELSKLQRELA-EAEAQA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1637 KESETSLYENNKLhgrVVLLEEEIQRLRVCSEQL-QTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSD 1715
Cdd:TIGR02169  500 RASEERVRGGRAV---EEVLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1716 FAALSKskleLQELHSCLTKILDDLRLNHEVALTERAE--------VLQDNK--NLLAEKREMMLRNEEALKEKEKLEES 1785
Cdd:TIGR02169  577 FLPLNK----MRDERRDLSILSEDGVIGFAVDLVEFDPkyepafkyVFGDTLvvEDIEAARRLMGKYRMVTLEGELFEKS 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1786 YFIlqkeisqlaqTNSHISANLLESQSenrtlRKDKSKLTLKIRELETLHsftaaQTAEDAMQIMEQMTKEKTETLASLE 1865
Cdd:TIGR02169  653 GAM----------TGGSRAPRGGILFS-----RSEPAELQRLRERLEGLK-----RELSSLQSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1866 DTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTR 1945
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1946 -DEVTSH-QKLEEERSVLNNQLLEMKKRES-----------------EFRKDADEEKASLQKSISLTSALLTEKDAELEK 2006
Cdd:TIGR02169  793 iPEIQAElSKLEEEVSRIEARLREIEQKLNrltlekeylekeiqelqEQRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  2007 LRNEVTVLRGENATAKS----LHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMIDF 2082
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKerdeLEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952

                          810
                   ....*....|....*
gi 568937372  2083 LNSVIVDLQRKNQDL 2097
Cdd:TIGR02169  953 LEDVQAELQRVEEEI 967
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 883-1779 1.22e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.22e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   883 KEEQFNVLSSELEklrenltdmEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQL 962
Cdd:TIGR02169  209 KAERYQALLKEKR---------EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   963 KLTKANENASF-LQKSIGEVTLKAEQSQQQAARKheeekkeleekllelEKKMETSYNQCQDLKAKYEKASSEtKTKHEE 1041
Cdd:TIGR02169  280 KIKDLGEEEQLrVKEKIGELEAEIASLERSIAEK---------------ERELEDAEERLAKLEAEIDKLLAE-IEELER 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1042 ILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLtylLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKL 1121
Cdd:TIGR02169  344 EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE---LKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1122 EKGSLLSKLIEVETKITLLQEdqqklwsvnetlhlEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL 1201
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEE--------------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1202 KMHMENDSLEASKvsmQVLIEELRFCKdklmAMSEKARAEKEHLEGQVKKL----------------TAENLVLVKDKDD 1265
Cdd:TIGR02169  487 KLQRELAEAEAQA---RASEERVRGGR----AVEEVLKASIQGVHGTVAQLgsvgeryataievaagNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1266 VIQKLqsayeELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAereNLLQTnrDLQFEK-------DTLrqgqe 1338
Cdd:TIGR02169  560 AKEAI-----ELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAV---DLVEF--DPKYEPafkyvfgDTL----- 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1339 kLSASLEAT---LQVKQLLSTEAETLRTQ--LDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHE 1413
Cdd:TIGR02169  625 -VVEDIEAArrlMGKYRMVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1414 KESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALEL 1493
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE----EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1494 QNGDLLAD-RESSIKTIGDLRRKydQEATNRRIVmqekmkllGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAK 1572
Cdd:TIGR02169  780 ALNDLEARlSHSRIPEIQAELSK--LEEEVSRIE--------ARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1573 KNLEKEHTSMIQAKDNLNAELKtcccEKNMLLRDglnLQEECQKLNEEIREIQQTLileKEARAKESEtslyennklhgr 1652
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELE----ELEAALRD---LESRLGDLKKERDELEAQL---RELERKIEE------------ 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1653 vvlLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKE-KELLSAEtaQLAANIETLKSDFAALSKSKLELQELHS 1731
Cdd:TIGR02169  908 ---LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpEEELSLE--DVQAELQRVEEEIRALEPVNMLAIQEYE 982

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 568937372  1732 CLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEK 1779
Cdd:TIGR02169  983 EVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEAINEN 1030
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 788-1301 2.20e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.20  E-value: 2.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   788 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQdslnQVNQVKETLEKELQTLKEKFASTSEEAV 867
Cdd:TIGR04523  160 KYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLK----KKIQKNKSLESQISELKKQNNQLKDNIE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   868 SAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQltKMN 947
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK--ELK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   948 DELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAE--------QSQQQAARKHEEEKKELEEKLLELEKKMETSYN 1019
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQ--LKKEltnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLES 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1020 QCQDLKAKYEKASSETKTKHEEI--LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKA-KSLTYLLTSAKKEIE 1096
Cdd:TIGR04523  392 QINDLESKIQNQEKLNQQKDEQIkkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiKNLDNTRESLETQLK 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1097 VMSEELRGLKS-------EKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSvnETLHLEKERVSEEKQVAE 1169
Cdd:TIGR04523  472 VLSRSINKIKQnleqkqkELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES--EKKEKESKISDLEDELNK 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1170 KRYqqehrdreslVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQV 1249
Cdd:TIGR04523  550 DDF----------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937372  1250 KKLTAENlvlvKDKDDVIQKLQSAYEELVKDQKAlVQEIEDLTTEKKSAAEK 1301
Cdd:TIGR04523  620 EKAKKEN----EKLSSIIKNIKSKKNKLKQEVKQ-IKETIKEIRNKWPEIIK 666
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
692-1319 4.31e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 4.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  692 ETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemedtlNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEK 771
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIE--------ELIKEKE---KELEEVLREINEISSELPELREELEKLEKE 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  772 LLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLET---ERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETL 848
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEErieELKKEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  849 EKELQTLKEKFASTSEEAVSAQTRMQDTVNKlhqkeeqfnvlSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENd 928
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEERIKELEEK-----------EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE- 373

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  929 IAEIMKMSGDNSsqLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtlkaeqsqqqaarkheeekkeleekll 1008
Cdd:PRK03918  374 LERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE---------------------------- 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1009 elekkMETSYNQCQDLKAKYEKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1087
Cdd:PRK03918  424 -----LKKAIEELKKAKGKCPVCGRELTEEHRkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1088 LTSAkKEIEVMSEELRGLKSEKqlyaQEANALKLEKgsLLSKLIEVETKITLLQEDQQKLwsvnETLHLEKERVSEEKQV 1167
Cdd:PRK03918  499 KELA-EQLKELEEKLKKYNLEE----LEKKAEEYEK--LKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDE 567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1168 AEKRYQQEHRDRESLVAEReklLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLmamsEKARAEKEHLEG 1247
Cdd:PRK03918  568 LEEELAELLKELEELGFES---VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL----DKAFEELAETEK 640

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372 1248 QVKKLTAENLVLVKDKDDviqklqSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1319
Cdd:PRK03918  641 RLEELRKELEELEKKYSE------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 335-807 5.65e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 5.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA---RDGHDQHVLELEAKMDQ 411
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAeeeLEEAEAELAEAEEALLE 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  412 LRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKspisEDPENTQTKLEHARTKELEQSLLFEKTKAD 491
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER----LERLEEELEELEEALAELEEEEEEEEEALE 445

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  492 KLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQE-------ISALQEKLEAIHTD 564
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvkAALLLAGLRGLAGA 525

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  565 HQGEMTSLKEHFGAREEAFQKEIKALHTATE----------KLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQ 634
Cdd:COG1196   526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDevaaaaieylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  635 QAMEELKVSFSKGIGTDSAEFAELKTQIERLR----LDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLE 710
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  711 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEgkLELE 790
Cdd:COG1196   686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP--PDLE 763

                         490
                  ....*....|....*..
gi 568937372  791 TLRQQLEGAEKQIKNLE 807
Cdd:COG1196   764 ELERELERLEREIEALG 780
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
701-1241 1.20e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 1.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  701 IIKEKEDSLEAVKARLDSAEDQHLVEmedtlnKLQEAEIKVKELEvlqakyteqsEVIGNFTSQLSAVKEKLLDLDALRK 780
Cdd:PRK02224  181 VLSDQRGSLDQLKAQIEEKEEKDLHE------RLNGLESELAELD----------EEIERYEEQREQARETRDEADEVLE 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  781 ANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFA 860
Cdd:PRK02224  245 EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  861 STSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNS 940
Cdd:PRK02224  325 ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  941 SQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSI--GEVTLKA----EQSQQQAARKHEEEKKELEEKLLELEKKM 1014
Cdd:PRK02224  405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVeeAEALLEAgkcpECGQPVEGSPHVETIEEDRERVEELEAEL 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1015 ETSYNQCQDLKAKYEKASSETKT-----KHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllT 1089
Cdd:PRK02224  485 EDLEEEVEEVEERLERAEDLVEAedrieRLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA---A 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1090 SAKKEIEVMSEELRGLKSEKQLYAQEANAL-KLEkgSLLSKLIEVETKITLLQEDQQKLWSVN----ETLHLEKERVSE- 1163
Cdd:PRK02224  562 EAEEEAEEAREEVAELNSKLAELKERIESLeRIR--TLLAAIADAEDEIERLREKREALAELNderrERLAEKRERKREl 639

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1164 --------------EKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQ---EELLKMHMENDSLEASKVSMQVLIEELrf 1226
Cdd:PRK02224  640 eaefdearieeareDKERAEEYLEQVEEKLDELREERDDLQAEIGAVEnelEELEELRERREALENRVEALEALYDEA-- 717

                         570
                  ....*....|....*
gi 568937372 1227 ckDKLMAMSEKARAE 1241
Cdd:PRK02224  718 --EELESMYGDLRAE 730
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1441-2006 1.35e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.50  E-value: 1.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1441 KLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQngdlLADRESSIKTIGDLRRKYDQEA 1520
Cdd:TIGR04523  128 KLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKE----KLNIQKNIDKIKNKLLKLELLL 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1521 TNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEK 1600
Cdd:TIGR04523  204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKI 283

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1601 NMLLRDGLNLQEECQKLN----EEIREIQQTLILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQTENFT 1676
Cdd:TIGR04523  284 KELEKQLNQLKSEISDLNnqkeQDWNKELKSELKNQEKKLEEIQNQISQNNK---IISQLNEQISQLKKELTNSESENSE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1677 LTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQ 1756
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1757 DNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHS 1836
Cdd:TIGR04523  441 EIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1837 F--TAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA------RLQNELDTLKENNLKTVEELNKSKELLSVENQKMEE 1908
Cdd:TIGR04523  521 SlkEKIEKLESEKKEKESKISDLEDELNKDDFELKKENlekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1909 FKKEIETLKQAAAQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQK 1988
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSII---KNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677

                          570
                   ....*....|....*...
gi 568937372  1989 SISLTSALLTEKDAELEK 2006
Cdd:TIGR04523  678 IIELMKDWLKELSLHYKK 695
PTZ00121 PTZ00121
MAEBL; Provisional
 368-966 1.51e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  368 AERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEE 447
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED 1403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  448 SITKGDLEQKSPISEDPENTQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVA----TVSEKSRIMELEKDLALRAQ 523
Cdd:PTZ00121 1404 KKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAeeakKKAEEAKKADEAKKKAEEAK 1483

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  524 EVAELRRRLESSKPPGD----VDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKalhtATEKLSK 599
Cdd:PTZ00121 1484 KADEAKKKAEEAKKKADeakkAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK----KAEELKK 1559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  600 ENEslRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKV----SFSKGIGTDSAEFAELKTQIERLRLDYQHEIES 675
Cdd:PTZ00121 1560 AEE--KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLyeeeKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  676 LQSKQDSE-RSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQ 754
Cdd:PTZ00121 1638 LKKKEAEEkKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  755 SEVIGNftsqlsAVKEKLLDLDALRKANSEGKLELETLRQQlEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGL 834
Cdd:PTZ00121 1718 AEELKK------AEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDE 1790

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  835 QDSLNQVNQVKETLEKE-------------LQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSElEKLRENL 901
Cdd:PTZ00121 1791 KRRMEVDKKIKDIFDNFaniieggkegnlvINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGE-DGNKEAD 1869

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372  902 TDMEAKFKEKDDREDQLVKAKEKLENDIAEIM----KMSGDNSSQLTKMNDELRLKERSVEELQLKLTK 966
Cdd:PTZ00121 1870 FNKEKDLKEDDEEEIEEADEIEKIDKDDIEREipnnNMAGKNNDIIDDKLDKDEYIKRDAEETREEIIK 1938
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 454-1307 1.74e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 1.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   454 LEQKSPISEDPENTQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRrrle 533
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI---- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   534 sskppgdvdmsLSLLQEISALQEKLEAIHTDHQGEMtslkehfgaREEAFQKEIKALHTATEKLSKENESLRSKLDHANK 613
Cdd:pfam02463  254 -----------ESSKQEIEKEEEKLAQVLKENKEEE---------KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   614 ENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMET 693
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   694 MQAKLMKIIKEKEDSLEAVKAR--------LDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQL 765
Cdd:pfam02463  394 EEELELKSEEEKEAQLLLELARqledllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   766 SAVKEKLLDLDALRKANSEGKLELETLRQQ-LEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQV 844
Cdd:pfam02463  474 LKETQLVKLQEQLELLLSRQKLEERSQKESkARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   845 KETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEK 924
Cdd:pfam02463  554 SATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   925 LENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASfLQKSIGEVTLKAEQSQQQAARKHEEEKKELE 1004
Cdd:pfam02463  634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL-QEKAESELAKEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1005 EKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSL 1084
Cdd:pfam02463  713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1085 TYLLTSAKKEIEVMSEElrgLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEE 1164
Cdd:pfam02463  793 EEKLKAQEEELRALEEE---LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1165 KQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEH 1244
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937372  1245 LEGQVKKLTAENLVLVKDKDD----VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDN 1307
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEelgkVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1589-2078 2.84e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 2.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1589 LNAELKTCccEKNMLLRDGLNLQEECQKLNEEIREIQQTLI-LEKEARAKESEtslyennklhgrVVLLEEEIQRLRVCS 1667
Cdd:COG1196   218 LKEELKEL--EAELLLLKLRELEAELEELEAELEELEAELEeLEAELAELEAE------------LEELRLELEELELEL 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1668 EQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVA 1747
Cdd:COG1196   284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1748 LTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLK 1827
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1828 IRELETLHSfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKM- 1906
Cdd:COG1196   444 LEEAAEEEA-ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGl 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1907 ---------EEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRK 1977
Cdd:COG1196   523 agavavligVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1978 DADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLS 2057
Cdd:COG1196   603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                         490       500
                  ....*....|....*....|.
gi 568937372 2058 SSSGNTDAQAEEDERAQESQQ 2078
Cdd:COG1196   683 ELAERLAEEELELEEALLAEE 703
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1387-2056 3.00e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.43  E-value: 3.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1387 SSLTKLLEEIKTCRAITDSEciqlLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGL---NEKITYL 1463
Cdd:pfam05483   81 SKLYKEAEKIKKWKVSIEAE----LKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikeNNATRHL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1464 TSEKEVACQKVAKLKKQQDSLLKEKSALELqngDLLADRESSIKTIGDLRrkydQEATNRRIVMQEKMKL-LGNIDALKK 1542
Cdd:pfam05483  157 CNLLKETCARSAEKTKKYEYEREETRQVYM---DLNNNIEKMILAFEELR----VQAENARLEMHFKLKEdHEKIQHLEE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1543 ELQER--KKENQ---------ELTSSKCDLSLLLKEAQDAKKNLEKEHT-------SMIQAKDNLNAELKTCCCEKNMLL 1604
Cdd:pfam05483  230 EYKKEinDKEKQvsllliqitEKENKMKDLTFLLEESRDKANQLEEKTKlqdenlkELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1605 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEE----EIQRLRVCSEQLQTENFTLtQE 1680
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtEQQRLEKNEDQLKIITMEL-QK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1681 KTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILD-------DLRLNHEVALTERAE 1753
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQarekeihDLEIQLTAIKTSEEH 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1754 VLQDNKNLLAEKREMMLRNEEALKEKEKLeesyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELET 1833
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKL-------LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1834 lhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEI 1913
Cdd:pfam05483  542 ----KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEN 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1914 ETLKQAAAQKSQQLSALQEENVKLAEELGRTRDE----VTSHQKLEEERSVLNNQLLEmkkrESEFRKDADEEKASLQKS 1989
Cdd:pfam05483  618 KALKKKGSAENKQLNAYEIKVNKLELELASAKQKfeeiIDNYQKEIEDKKISEEKLLE----EVEKAKAIADEAVKLQKE 693

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372  1990 ISL-TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2056
Cdd:pfam05483  694 IDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 821-1885 3.92e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.11  E-value: 3.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   821 TKELQEK-ELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLH-------QKEEQFNVLSS 892
Cdd:pfam01576   17 VKERQQKaESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHelesrleEEEERSQQLQN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   893 ELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 972
Cdd:pfam01576   97 EKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAK 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   973 FLQK---------SIGEVTLKAEQSQQQAARKHEEEKKELEEKLLElekkmetsynQCQDLKAKYEKASSETKTKHEEiL 1043
Cdd:pfam01576  177 SLSKlknkheamiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQE----------QIAELQAQIAELRAQLAKKEEE-L 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1044 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQ------LYAQEAN 1117
Cdd:pfam01576  246 QAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR---NKAEKQRRDLGEELEALKTELEdtldttAAQQELR 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1118 ALKLEKGSLLSKLIEVETKI--TLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKryqqehrDRESLVAEREKLLKEINA 1195
Cdd:pfam01576  323 SKREQEVTELKKALEEETRSheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK-------AKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1196 AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYE 1275
Cdd:pfam01576  396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1276 ELVKDQKALVQeiedLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLS 1355
Cdd:pfam01576  476 LLQEETRQKLN----LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1356 TEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTklleeiktcraitdsecIQLLHEKESLAASERTlLAEKEELLSEN 1435
Cdd:pfam01576  552 RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL-----------------VDLDHQRQLVSNLEKK-QKKFDQMLAEE 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1436 RIITeklSKQSEEVARLEMGLNEKITyltsekevacqKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDL--- 1512
Cdd:pfam01576  614 KAIS---ARYAEERDRAEAEAREKET-----------RALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgkn 679

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1513 -------RRKYDQEATNRRIVMQE-----------KMKLLGNIDALK----KELQERKKENQEltsskcDLSLLLKEAQD 1570
Cdd:pfam01576  680 vhelersKRALEQQVEEMKTQLEEledelqatedaKLRLEVNMQALKaqfeRDLQARDEQGEE------KRRQLVKQVRE 753

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1571 AKKNLEKEHTSMIQA---KDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEAR------AKESET 1641
Cdd:pfam01576  754 LEAELEDERKQRAQAvaaKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRdeilaqSKESEK 833

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1642 SLyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSK 1721
Cdd:pfam01576  834 KL---KNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLND 910

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1722 SKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMmlrnEEALKEKEKLEESYFilqkeISQLAQTNS 1801
Cdd:pfam01576  911 RLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEM----EGTVKSKFKSSIAAL-----EAKIAQLEE 981

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1802 HISANLLESQSENRTLRKDKSKL--TLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1879
Cdd:pfam01576  982 QLEQESRERQAANKLVRRTEKKLkeVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELD 1061


                   ....*.
gi 568937372  1880 TLKENN 1885
Cdd:pfam01576 1062 DATESN 1067
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1159-1798 4.60e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 4.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1159 ERVSEEKQVAEK----RYQQEHRDRESLVAEREKLLKEINAAQEELlkmhmendsleaskvsmqvlieelrfckDKLMAM 1234
Cdd:COG1196   203 EPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAEL----------------------------EELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1235 SEKARAEKEHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKA 1314
Cdd:COG1196   255 LEELEAELAELEAELEELRLE-----------LEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1315 ERENLLQTNRDLQFEKDTLRQGQEKLSASLEAT-LQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLL 1393
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAeAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1394 EEIKTCRAITDsECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQK 1473
Cdd:COG1196   404 ELEEAEEALLE-RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1474 VAKLKKQQDSLLKEKSALELQNGDLLADREssIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERkkenqe 1553
Cdd:COG1196   483 LEELAEAAARLLLLLEAEADYEGFLEGVKA--ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE------ 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1554 ltsskcDLSLLLKEAQDAKKNLEKEHTSMIQAKdnlnaelktccceknMLLRDGLNLQEECQKLNEEIREIQQTLILEKE 1633
Cdd:COG1196   555 ------DDEVAAAAIEYLKAAKAGRATFLPLDK---------------IRARAALAAALARGAIGAAVDLVASDLREADA 613

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1634 ARAKESETSL---YENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIE 1710
Cdd:COG1196   614 RYYVLGDTLLgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1711 TLKSDFAALSKSKLELQELhscltkiLDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQ 1790
Cdd:COG1196   694 ELEEALLAEEEEERELAEA-------EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                  ....*...
gi 568937372 1791 KEISQLAQ 1798
Cdd:COG1196   767 RELERLER 774
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1267-1857 6.06e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 6.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1267 IQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEkqmsLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEA 1346
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1347 TLQVKQLLsteaETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKtcraitdsECIQLLHEKESLAASERTLLA 1426
Cdd:PRK03918  233 LEELKEEI----EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--------EKVKELKELKEKAEEYIKLSE 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1427 EKEELLSENRIITEKLSKQSEEVArlemGLNEKITYLTSEKEvacqKVAKLKKQQDSLLKEKSALE-----LQNGDLLAD 1501
Cdd:PRK03918  301 FYEEYLDELREIEKRLSRLEEEIN----GIEERIKELEEKEE----RLEELKKKLKELEKRLEELEerhelYEEAKAKKE 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1502 RESSIK------TIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSK-----CDLSL------- 1563
Cdd:PRK03918  373 ELERLKkrltglTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvCGRELteehrke 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1564 LLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEK-EARAKESETS 1642
Cdd:PRK03918  453 LLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLKKYNLEElEKKAEEYEKL 530

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1643 LYENNKLHGRVVLLEEEIQRLrvcsEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAET-AQLAANIETLKS---DFAA 1718
Cdd:PRK03918  531 KEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELEPfynEYLE 606

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1719 LSKSKLELQELHscltKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLR-----NEEALKEKEKLEESYFILQKEI 1793
Cdd:PRK03918  607 LKDAEKELEREE----KELKKLEEELDKAFEELAETEKRLEELRKELEELEKKyseeeYEELREEYLELSRELAGLRAEL 682

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372 1794 SQLAQTNSHISANLLESQSENRTLRKDKSKLTL-------------KIRELETLHSFTA-AQTAEDAMQIMEQMTKEK 1857
Cdd:PRK03918  683 EELEKRREEIKKTLEKLKEELEEREKAKKELEKlekalerveelreKVKKYKALLKERAlSKVGEIASEIFEELTEGK 760
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 344-960 7.87e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   344 RKISGTTALQEALKEKQQHIEQLLAE-----RDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE------------ 406
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEElnkkiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEdaeerlakleae 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   407 -----AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSpisedpENTQTKLEHArTKELEQ 481
Cdd:TIGR02169  331 idkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL------KDYREKLEKL-KREINE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   482 SLLFEKTKADKLQR---ELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLES-SKPPGDVDMSLSLLQ-------- 549
Cdd:TIGR02169  404 LKRELDRLQEELQRlseELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQlAADLSKYEQELYDLKeeydrvek 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   550 EISALQEKLEAIHTDHQGEMTSLKEHFgAREEAFQKEIKALHTATEKLSKENE--------SLRSKLDHANKENSDV--- 618
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARASEERVRGGR-AVEEVLKASIQGVHGTVAQLGSVGEryataievAAGNRLNNVVVEDDAVake 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   619 -IALWKSKLE--------TAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQI-----------ERLRLDYQHEIE---- 674
Cdd:TIGR02169  563 aIELLKRRKAgratflplNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfkyvfgdtlvvEDIEAARRLMGKyrmv 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   675 ----------------SLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAE 738
Cdd:TIGR02169  643 tlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   739 ikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEgklELETLRQQLEGAEKQIKNLETERNAE----- 813
Cdd:TIGR02169  723 ---KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEA---RIEELEEDLHKLEEALNDLEARLSHSripei 796

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   814 SSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQT-------LKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ 886
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQElqeqridLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372   887 FNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEEL 960
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 355-1108 9.80e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 9.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   355 ALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:TIGR02169  215 ALLKEKREYEGyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   433 EKRKVEdlqfrvEEESITKGDLEQKSPISEDPENTQTKLEHARTK------ELEQSLLFEKTKADKLQRELEDTRVATVS 506
Cdd:TIGR02169  295 KIGELE------AEIASLERSIAEKERELEDAEERLAKLEAEIDKllaeieELEREIEEERKRRDKLTEEYAELKEELED 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   507 EKSRIMELEKDLALRAQEVAELRRRLESSKPPGDvdmslSLLQEISALQEKLEAIHT---DHQGEMTSLKE---HFGARE 580
Cdd:TIGR02169  369 LRAELEEVDKEFAETRDELKDYREKLEKLKREIN-----ELKRELDRLQEELQRLSEelaDLNAAIAGIEAkinELEEEK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   581 EAFQKEIKA----LHTATEKLSKENESL---RSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSFS--KGIGTD 651
Cdd:TIGR02169  444 EDKALEIKKqewkLEQLAADLSKYEQELydlKEEYDRVEKELSKL----QRELAEAEAQARASEERVRGGRAveEVLKAS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   652 SAEFAELKTQIERLRLDYQHEIESLQSK-------QDSERSAHA----KEMETMQAKLMKIIKEKEDSLEAVKARLDSAE 720
Cdd:TIGR02169  520 IQGVHGTVAQLGSVGERYATAIEVAAGNrlnnvvvEDDAVAKEAiellKRRKAGRATFLPLNKMRDERRDLSILSEDGVI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   721 DQ--HLVEMEDtlnKLQEAEIKVKELEVLQAKYTEQSEVIGNFtsQLSAVKEKLLD--------LDALRKANS---EGKL 787
Cdd:TIGR02169  600 GFavDLVEFDP---KYEPAFKYVFGDTLVVEDIEAARRLMGKY--RMVTLEGELFEksgamtggSRAPRGGILfsrSEPA 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   788 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAV 867
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   868 SAQTRMQDTVNKLHQKEEQFNVLSSELEKL--------------------------RENLTDMEAKFKEKDDREDQLVKA 921
Cdd:TIGR02169  755 NVKSELKELEARIEELEEDLHKLEEALNDLearlshsripeiqaelskleeevsriEARLREIEQKLNRLTLEKEYLEKE 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   922 KEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAEQSQQQaaRKHEEEKK 1001
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE--LEAQLRELE--RKIEELEA 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1002 ELEEKLLELEKKMETSYNQCQDLKAkYEKASSETKTKHEEI--LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQAD 1079
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSE-IEDPKGEDEEIPEEElsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLD 989

                          810       820
                   ....*....|....*....|....*....
gi 568937372  1080 KAKSLTYLLTSAKKEIEVMSEELRGLKSE 1108
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 870-1719 1.93e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   870 QTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEA------KFKEKDDREDQL-----VKAKEKLENDIAEIMKMSGD 938
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELERQLKSLERqaekaeRYKELKAELRELelallVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   939 NSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEkkeleekllelekkmetsy 1018
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL------------------- 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1019 nqcQDLKAKYEKAssetktkhEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVM 1098
Cdd:TIGR02168  312 ---ANLERQLEEL--------EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1099 SEELRglksekqlyaQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEK---QVAEKRYQQE 1175
Cdd:TIGR02168  381 LETLR----------SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqaELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1176 H--RDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFcKDKLMAMSEKARAEKEHLEGQVKKL- 1252
Cdd:TIGR02168  451 ElqEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG-FSEGVKALLKNQSGLSGILGVLSELi 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1253 -------TAENLVLVKDKDDViqklqsayeeLVKDQKALVQEIEDLtteKKSAAEKQMSL---DNTCLTLKAERENLLQT 1322
Cdd:TIGR02168  530 svdegyeAAIEAALGGRLQAV----------VVENLNAAKKAIAFL---KQNELGRVTFLpldSIKGTEIQGNDREILKN 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1323 NRDLQFEKDTLRQGQEKLSASLEATLQvkqlLSTEAETLRTQLDCASK---ALRKAELDMRQLQTS----------NSSL 1389
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKLRKALSYLLG----GVLVVDDLDNALELAKKlrpGYRIVTLDGDLVRPGgvitggsaktNSSI 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1390 TKLLEEIKTCRaitdseciQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEV 1469
Cdd:TIGR02168  673 LERRREIEELE--------EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1470 ACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQeaTNRRIVMQEKMkllgnIDALKKELQERKK 1549
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ--LKEELKALREA-----LDELRAELTLLNE 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1550 ENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNmllrdglNLQEECQKLNEEIREIQQTLI 1629
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE-------ELESELEALLNERASLEEALA 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1630 LEKEARAKESEtslyENNKLHGRVVLLEEEIQRLRVCSEQLQTE------NFTLTQEKTNSEQKV--EEIIKEKELLSAE 1701
Cdd:TIGR02168  891 LLRSELEELSE----ELRELESKRSELRRELEELREKLAQLELRleglevRIDNLQERLSEEYSLtlEEAEALENKIEDD 966

                          890
                   ....*....|....*...
gi 568937372  1702 TAQLAANIETLKSDFAAL 1719
Cdd:TIGR02168  967 EEEARRRLKRLENKIKEL 984
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1161-2012 2.99e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 2.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1161 VSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLkmhMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARA 1240
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKE---QAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1241 EKEhlegqvkkltaENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDlttEKKSAAEKQMSLDNTCLTLKAERENLL 1320
Cdd:pfam02463  241 LLQ-----------ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK---EKKLQEEELKLLAKEEEELKSELLKLE 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1321 QTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTE---AETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIK 1397
Cdd:pfam02463  307 RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKElkeLEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1398 TCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKL 1477
Cdd:pfam02463  387 SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1478 KKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSS 1557
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIS 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1558 KCDLSLLLKEAQ--DAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEAR 1635
Cdd:pfam02463  547 TAVIVEVSATADevEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1636 AKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSD 1715
Cdd:pfam02463  627 GILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1716 FAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQ 1795
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1796 LAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQ 1875
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1876 NELDTLKENNLKTVEELNKSKELLSVENQKMEefKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVT------ 1949
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEE--KKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEelllee 944

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937372  1950 --------SHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVT 2012
Cdd:pfam02463  945 adekekeeNNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 354-1206 5.44e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.44  E-value: 5.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   434 KRKVEDLQFRVEEESITKGDLEQKspisedpENTQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIME 513
Cdd:pfam02463  253 IESSKQEIEKEEEKLAQVLKENKE-------EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   514 LEKDLALRAQEVAELRRRLESSKPPGDVDmsLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTA 593
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAE--EEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   594 TEKLSKENESLRSKLDHA----NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDY 669
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLkeekKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   670 QHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKAR----------LDSAEDQHLVEMEDTLNKLQEAEI 739
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGrlgdlgvaveNYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   740 KVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANS 819
Cdd:pfam02463  564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   820 ITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRE 899
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   900 NLTDMEAKFKEKDDREDQLVKAKEKLENDIaeimKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIG 979
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEE----KSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   980 EVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKA 1059
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1060 AQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLyaQEANALKLEKGSLLSKLIEVETKITL 1139
Cdd:pfam02463  880 EEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILL--KYEEEPEELLLEEADEKEKEENNKEE 957

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937372  1140 LQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHME 1206
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLE 1024
PTZ00121 PTZ00121
MAEBL; Provisional
 1394-2100 6.27e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 6.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1394 EEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNE-----KITYLTSEKE 1468
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKaeeakKADEAKKKAE 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1469 VACQKVAKLKKQQDSLlKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERK 1548
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEA-KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1549 KENQELTSSKCDLslllKEAQDAKKNLEKEHTSmiqakdnlnAELKTCCCEKNMllrdglnlQEECQKLNEEIREIQQTL 1628
Cdd:PTZ00121 1405 KKADELKKAAAAK----KKADEAKKKAEEKKKA---------DEAKKKAEEAKK--------ADEAKKKAEEAKKAEEAK 1463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1629 ILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQtenftltqEKTNSEQKVEEIIKEKELLSAETAQLAAn 1708
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEEAK---KADEAKKKAEEAKKKADEAK--------KAAEAKKKADEAKKAEEAKKADEAKKAE- 1531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1709 iETLKSDFAALSKSKLELQELhscltKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEA-LKEKEKLEESYF 1787
Cdd:PTZ00121 1532 -EAKKADEAKKAEEKKKADEL-----KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArIEEVMKLYEEEK 1605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1788 ILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDA-MQIMEQMTKEKTETLASLED 1866
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAeEAKKAEEDKKKAEEAKKAEE 1685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1867 TKQTNArlqnELDTLKENNLKTVEELNKSKEllsVENQKMEEFKKEIETLKQaaaqKSQQLSALQEENVKLAEELGRTRD 1946
Cdd:PTZ00121 1686 DEKKAA----EALKKEAEEAKKAEELKKKEA---EEKKKAEELKKAEEENKI----KAEEAKKEAEEDKKKAEEAKKDEE 1754

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1947 EVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQ-----KSISLTSALLTEKDAELEKLRNEVTVLRGENATA 2021
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEvdkkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKE 1834

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2022 KSLHSVVQTLESDKVKlelkvknlelQLKENKRQLSSSSGNTDAQA-------EEDERAQESQQMIDFLNSVIVDLQRKN 2094
Cdd:PTZ00121 1835 VADSKNMQLEEADAFE----------KHKFNKNNENGEDGNKEADFnkekdlkEDDEEEIEEADEIEKIDKDDIEREIPN 1904


                  ....*.
gi 568937372 2095 QDLKMK 2100
Cdd:PTZ00121 1905 NNMAGK 1910
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1046-1628 8.00e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 8.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1046 LQKMLADTEDKLKAAQEANRDLMQDM-----EELKTQADKAKSLTYLLTSAKKEIEVMSEELRglkSEKQLYAQEANALK 1120
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDRIEQLiseheVEITGLTEKASSARSQANSIQSQLEIIQEQAR---NQNSMYMRQLSDLE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1121 LEKGSLLSKLIEVETkitlLQEDQQKlwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRES--LVAEREKLLKEINAAQE 1198
Cdd:pfam15921  324 STVSQLRSELREAKR----MYEDKIE--------ELEKQLVLANSELTEARTERDQFSQESgnLDDQLQKLLADLHKREK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1199 ELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELV 1278
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1279 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQfekdtlrqgqeKLSASLEATLQVKQLLSTEA 1358
Cdd:pfam15921  472 STKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-----------KLRSRVDLKLQELQHLKNEG 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1359 ETLR-TQLDCASKALRKAELD--MRQLQTSNSSLTKLLEEIKTCRAITDSECIQLlhEKEslaASERTLLAEKEELLSEN 1435
Cdd:pfam15921  541 DHLRnVQTECEALKLQMAEKDkvIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL--EKE---INDRRLELQEFKILKDK 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1436 RiiTEKLSKQSEEVARLEMglnEKITYLTSEKEvACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKtigDLRRK 1515
Cdd:pfam15921  616 K--DAKIRELEARVSDLEL---EKVKLVNAGSE-RLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR---NFRNK 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1516 YDQ-EATNRRIVMQEKmKLLGNIDALKKELQERKKEN-----------QELTSSKCDLSLLLKEAQ---DAKKNLEKEHT 1580
Cdd:pfam15921  687 SEEmETTTNKLKMQLK-SAQSELEQTRNTLKSMEGSDghamkvamgmqKQITAKRGQIDALQSKIQfleEAMTNANKEKH 765

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 568937372  1581 SMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTL 1628
Cdd:pfam15921  766 FLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
354-899 1.14e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:COG4913   255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  433 EK-RKVEDLQFRVEEESITKGDLEQKSpisEDPENTQTKLEHARTKELEQsllFEKTKA------DKLQRELEDTRVATV 505
Cdd:COG4913   335 NGgDRLEQLEREIERLERELEERERRR---ARLEALLAALGLPLPASAEE---FAALRAeaaallEALEEELEALEEALA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  506 SEKSRIMELEKDLALRAQEVAELRRRlESSKPPGDVDMSLSLLQEISALQEKLEAIhtdhqGEMTSLKEhfgaREEAFQK 585
Cdd:COG4913   409 EAEAALRDLRRELRELEAEIASLERR-KSNIPARLLALRDALAEALGLDEAELPFV-----GELIEVRP----EEERWRG 478

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  586 EI-KALHT--------------ATEKLskENESLRSKLDhankenSDVIALWKSKLETAIASHQQAMEELKVSfskgigt 650
Cdd:COG4913   479 AIeRVLGGfaltllvppehyaaALRWV--NRLHLRGRLV------YERVRTGLPDPERPRLDPDSLAGKLDFK------- 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  651 DSAEFAELKTQIERlRLDYqHEIESLQSKQDSERS------------AHAKEMETMQAKLMKIIKEKEDSLEAVKARLDS 718
Cdd:COG4913   544 PHPFRAWLEAELGR-RFDY-VCVDSPEELRRHPRAitragqvkgngtRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAE 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  719 AEDQhlvemedtlnkLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETL 792
Cdd:COG4913   622 LEEE-----------LAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAAL 690

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  793 RQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTR 872
Cdd:COG4913   691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR 768

                         570       580
                  ....*....|....*....|....*..
gi 568937372  873 mQDTVNKLHQKEEQFNVLSSELEKLRE 899
Cdd:COG4913   769 -ENLEERIDALRARLNRAEEELERAMR 794
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
659-1255 1.34e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.97  E-value: 1.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  659 KTQIERLRLDYQHEIESLQS----KQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKL 734
Cdd:PRK02224  175 RLGVERVLSDQRGSLDQLKAqieeKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREEL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  735 QEAEikvKELEVLQAKYTEqsevignftsqlsAVKEKlldlDALRKansegklELETLRQQLEGAEKQIKNLETERNAES 814
Cdd:PRK02224  254 ETLE---AEIEDLRETIAE-------------TERER----EELAE-------EVRDLRERLEELEEERDDLLAEAGLDD 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  815 SKANSITKELQEKELVLTGLQDSLNQV-------NQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 887
Cdd:PRK02224  307 ADAEAVEARREELEDRDEELRDRLEECrvaaqahNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  888 NVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAeimkmsgdnssqltkmndELRLKERSVEElqlkltKA 967
Cdd:PRK02224  387 EELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREA------------------ELEATLRTARE------RV 442

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  968 NENASFLqksigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-----KHEEI 1042
Cdd:PRK02224  443 EEAEALL-----EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrieRLEER 517

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1043 LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQLYAQEANAL-KL 1121
Cdd:PRK02224  518 REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA---AEAEEEAEEAREEVAELNSKLAELKERIESLeRI 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1122 EkgSLLSKLIEVETKITLLQEDQQKLWSVN----ETLHLEKERVSE-EKQVAEKRYQQEHRDRESLVAEREKLLKEINAA 1196
Cdd:PRK02224  595 R--TLLAAIADAEDEIERLREKREALAELNderrERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDEL 672

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372 1197 QEellkmhmENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARA------EKEHLEGQVKKLTAE 1255
Cdd:PRK02224  673 RE-------ERDDLQAEIGAVENELEELEELRERREALENRVEAlealydEAEELESMYGDLRAE 730
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 779-1533 1.41e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 56.90  E-value: 1.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   779 RKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTglqdslnqvnQVKETLEKELQTLKEk 858
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYH----------ERKQVLEKELKHLRE- 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   859 fastseeavsAQTRMQDTVNKLHQKEEQFNvlssELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEND-----IAEIM 933
Cdd:TIGR00618  234 ----------ALQQTQQSHAYLTQKREAQE----EQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHI 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   934 KMSGDNSSQLTKMNDELRLKERSVE-ELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEK 1012
Cdd:TIGR00618  300 KAVTQIEQQAQRIHTELQSKMRSRAkLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQ 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1013 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLK-AAQEANRDLMQDMEELKTQAdkaksLTYLLTSA 1091
Cdd:TIGR00618  380 HIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQlAHAKKQQELQQRYAELCAAA-----ITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1092 KKEIEVMSEELRGLKSEKQLYAQEANALKLEKgsllSKLIEVETKITLLQEDQQKLwsVNETLHLEKE------------ 1159
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQET----RKKAVVLARLLELQEEPCPL--CGSCIHPNPArqdidnpgpltr 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1160 RVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKAR 1239
Cdd:TIGR00618  529 RMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1240 AEKEHLEGQVKKLTAEnlvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaEKQMSLDNTCLTLKAERENL 1319
Cdd:TIGR00618  609 MLACEQHALLRKLQPE-----QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR--EHALSIRVLPKELLASRQLA 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1320 LQT----NRDLQFEKDTLRQGQEKLSASLEATL-------QVKQLLSTEAETLRTQLDCASKALRKAELDMR---QLQTS 1385
Cdd:TIGR00618  682 LQKmqseKEQLTYWKEMLAQCQTLLRELETHIEeydrefnEIENASSSLGSDLAAREDALNQSLKELMHQARtvlKARTE 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1386 NSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENR--IITEKLSKQSEEVARLEMGLN--EKIT 1461
Cdd:TIGR00618  762 AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIpsDEDILNLQCETLVQEEEQFLSrlEEKS 841

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372  1462 YLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKL 1533
Cdd:TIGR00618  842 ATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSE 913
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
846-1375 1.58e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  846 ETLEkELQTLKEKFASTSEEAvsAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 925
Cdd:COG4913   252 ELLE-PIRELAERYAAARERL--AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  926 ENDIAEImkmSGDNSSQLtkmndelrlkERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 1005
Cdd:COG4913   329 EAQIRGN---GGDRLEQL----------EREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1006 KLLELEKKMETSYnqcqDLKAKYEKASSETKTKHEEIL----------QNLQKMLADTEDKLKAAQEANR---DLMQDME 1072
Cdd:COG4913   396 LEEELEALEEALA----EAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEALGLDEAELPfvgELIEVRP 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1073 E-----------LKTQAdkakslTYLLTSAKKEIEV--------MSEELRGLKSEKQLyaQEANALKLEKGSLLSKLIEV 1133
Cdd:COG4913   472 EeerwrgaiervLGGFA------LTLLVPPEHYAAAlrwvnrlhLRGRLVYERVRTGL--PDPERPRLDPDSLAGKLDFK 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1134 ETKIT--LLQE--DQQKLWSVN--ETLHLEKERVSEEKQVAEKRYQQEHRDR-----------------ESLVAEREKLL 1190
Cdd:COG4913   544 PHPFRawLEAElgRRFDYVCVDspEELRRHPRAITRAGQVKGNGTRHEKDDRrrirsryvlgfdnraklAALEAELAELE 623

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1191 KEINAAQEELLKMHMENDSLEASKVSMQVLiEELRFCKDKLMAmsekARAEKEHLEGQVKKLTAENlvlvkdkdDVIQKL 1270
Cdd:COG4913   624 EELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVAS----AEREIAELEAELERLDASS--------DDLAAL 690

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1271 QSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEatlQV 1350
Cdd:COG4913   691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER---EL 767

                         570       580
                  ....*....|....*....|....*
gi 568937372 1351 KQLLSTEAETLRTQLDCASKALRKA 1375
Cdd:COG4913   768 RENLEERIDALRARLNRAEEELERA 792
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2173-2189 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 568937372  2173 RPYCEICEMFGHWATNC 2189
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 690-1143 1.77e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.57  E-value: 1.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   690 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQLSAVK 769
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ----LNQLKDEQNKI---KKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   770 EKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQ--------------IKNLETERNAESSKANSITKELQEKELVLTG 833
Cdd:TIGR04523  295 SEISDLNNQKEQDwnKELKSELKNQEKKLEEIQNQisqnnkiisqlneqISQLKKELTNSESENSEKQRELEEKQNEIEK 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   834 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 913
Cdd:TIGR04523  375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   914 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAA 993
Cdd:TIGR04523  455 IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKK 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   994 RKHEeekkeleekllelekkmETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKmLADTEDKLKAAQEANRDLMQDME- 1072
Cdd:TIGR04523  535 EKES-----------------KISDLEDELNKDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEk 596

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372  1073 -------ELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQED 1143
Cdd:TIGR04523  597 ekkdlikEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTK 674
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 754-972 2.08e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  754 QSEVIGNFTSQLSAVKEKLL----DLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKEL 829
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAelekELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  830 VLTGLQDSLNQVNQvkeTLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 909
Cdd:COG4942    98 ELEAQKEELAELLR---ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937372  910 EKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 972
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 949-1786 2.44e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 2.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   949 ELRLKERSVEELqLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKheeekkeLEEKLLELEKKMETSYNQCQDLKAKY 1028
Cdd:pfam02463  164 GSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLN 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1029 EKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTylltsakKEIEVMSEELRGLKSE 1108
Cdd:pfam02463  236 EERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA-------KEEEELKSELLKLERR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1109 KQLYAQEANALKLEKGSLLSKLIEVETKITllqEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREK 1188
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIE---ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1189 LLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKL-TAENLVLVKDKDDVI 1267
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEkEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1268 QKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEAT 1347
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1348 LQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQlLHEKESLAASERTLLAE 1427
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ-LDKATLEADEDDKRAKV 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1428 KEELLSENRIITEKLSK-----QSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADR 1502
Cdd:pfam02463  625 VEGILKDTELTKLKESAkakesGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1503 ESSIKTIgdLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSK------CDLSLLLKEAQDAKKNLE 1576
Cdd:pfam02463  705 EQREKEE--LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKkeekeeEKSELSLKEKELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1577 KEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVV-L 1655
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEeE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1656 LEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAalsKSKLELQELHSCLTK 1735
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK---EEAEILLKYEEEPEE 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 568937372  1736 ILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESY 1786
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1740-2131 4.51e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.47  E-value: 4.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1740 LRLNHEVALTERAEVLQDN--KNLLAEKREMMLRNE----EALKEKEKLEESYFILQ---KEISQLAQTNSHISANLLE- 1809
Cdd:COG5022   832 LRETEEVEFSLKAEVLIQKfgRSLKAKKRFSLLKKEtiylQSAQRVELAERQLQELKidvKSISSLKLVNLELESEIIEl 911

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1810 SQSENRTLRKDKSKLTLKIRELETLHsftaaqtaeDAMQIMEQMTKEKTEtlasledtKQTNARLQNELDTLKENNlKTV 1889
Cdd:COG5022   912 KKSLSSDLIENLEFKTELIARLKKLL---------NNIDLEEGPSIEYVK--------LPELNKLHEVESKLKETS-EEY 973

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1890 EELNKSKELLSVENQKMEEfkkEIETLKQAAAQKSQQLSALQEEnvklAEELGRTRDEVTSHQKleeersvlnnqllemk 1969
Cdd:COG5022   974 EDLLKKSTILVREGNKANS---ELKNFKKELAELSKQYGALQES----TKQLKELPVEVAELQS---------------- 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1970 krESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELq 2048
Cdd:COG5022  1031 --ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2049 lkeNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQS 2128
Cdd:COG5022  1104 ---TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEK 1180


                  ...
gi 568937372 2129 KKK 2131
Cdd:COG5022  1181 RLY 1183
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1353-1919 5.28e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 55.13  E-value: 5.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1353 LLSTEAETLRTQLDCASKalRKAELDMRqlqtsnsslTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELL 1432
Cdd:pfam05557   31 ELEKKASALKRQLDRESD--RNQELQKR---------IRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1433 SENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNgDLLADRESSIKtigDL 1512
Cdd:pfam05557  100 ADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQ-SSLAEAEQRIK---EL 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1513 RRKYDQEATNRRIVMQEKMKLLgNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQA------K 1586
Cdd:pfam05557  176 EFEIQSQEQDSEIVKNSKSELA-RIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREEKYREEAatleleK 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1587 DNLNAELKTCcceKNMLLRDGLNLQEEcQKLNEEIREIQQTLILEKEarakESETSLYENNKLHGRVVLLEEEIQRLRVC 1666
Cdd:pfam05557  255 EKLEQELQSW---VKLAQDTGLNLRSP-EDLSRRIEQLQQREIVLKE----ENSSLTSSARQLEKARRELEQELAQYLKK 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1667 SEQLQTENftltqeKTNSEQKvEEIIKEKELLSAETAQLAANIETLKSDFaALSKSKLELQELHSCLTKILDDLRlNHEV 1746
Cdd:pfam05557  327 IEDLNKKL------KRHKALV-RRLQRRVLLLTKERDGYRAILESYDKEL-TMSNYSPQLLERIEEAEDMTQKMQ-AHNE 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1747 ALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFIlQKEISQLAQTNSHISA---------NLLESQSENRTL 1817
Cdd:pfam05557  398 EMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYS-KEEVDSLRRKLETLELerqrlreqkNELEMELERRCL 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1818 RKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLkenNLKTVEELNKSKE 1897
Cdd:pfam05557  477 QGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTM---NFKEVLDLRKELE 553

                          570       580
                   ....*....|....*....|...
gi 568937372  1898 LLSVENQKMEE-FKKEIETLKQA 1919
Cdd:pfam05557  554 SAELKNQRLKEvFQAKIQEFRDV 576
PTZ00121 PTZ00121
MAEBL; Provisional
 1611-2107 9.97e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 9.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1611 QEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQ--KV 1688
Cdd:PTZ00121 1117 AEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEElrKA 1196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1689 EEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREM 1768
Cdd:PTZ00121 1197 EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE 1276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1769 MLRNEEALK--EKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDA 1846
Cdd:PTZ00121 1277 ARKADELKKaeEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1847 MQIMEQMTKEKTETLASLEDTKQTNA--------RLQNELDTLKENNLKTVEELNKSKELL---------SVENQKMEEF 1909
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKKADAakkkaeekKKADEAKKKAEEDKKKADELKKAAAAKkkadeakkkAEEKKKADEA 1436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1910 KKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKaslqKS 1989
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK----KA 1512

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1990 ISLTSALLTEKDAELEKLrnEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEE 2069
Cdd:PTZ00121 1513 DEAKKAEEAKKADEAKKA--EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 568937372 2070 DERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEA 2107
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA 1628
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1736-2069 1.01e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 1.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1736 ILDDLRLNHEVALTERAEVLQdNKNLLAEKREmmLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENR 1815
Cdd:TIGR02169  192 IIDEKRQQLERLRREREKAER-YQALLKEKRE--YEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1816 TLRKDKSKLTLKIRELetlhsftaaqTAEDAMQIMEQMTkektETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKS 1895
Cdd:TIGR02169  269 EIEQLLEELNKKIKDL----------GEEEQLRVKEKIG----ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1896 KELLSVENQKMEEFKKEIETLKQAAAQKSQQLSAL----QEENVKLAEELGRTRDEVTSHQKLEEERSVLN---NQLLEM 1968
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEKLKREINELKrelDRLQEE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1969 KKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTlESDKVKLELKVKNLELQ 2048
Cdd:TIGR02169  415 LQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE-EYDRVEKELSKLQRELA 493

                          330       340
                   ....*....|....*....|.
gi 568937372  2049 LKENKRQLSSSSGNTDAQAEE 2069
Cdd:TIGR02169  494 EAEAQARASEERVRGGRAVEE 514
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 843-1710 1.16e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.28  E-value: 1.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   843 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLT---DMEAKFKEKDDREDQLV 919
Cdd:TIGR00606  203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSkimKLDNEIKALKSRKKQME 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   920 KAKEKLENDIAEIMKMSGDNSSQLTKMND-ELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEE 998
Cdd:TIGR00606  283 KDNSELELKMEKVFQGTDEQLNDLYHNHQrTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   999 EKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEA-----------NRDL 1067
Cdd:TIGR00606  363 IRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQadeirdekkglGRTI 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1068 MQDMEELKTQADKAKSLTYL---LTSAKKEIEVMSEELRglKSEKQLYAQEANA----LKLEKGSLLSKLIEVETKITLL 1140
Cdd:TIGR00606  443 ELKKEILEKKQEELKFVIKElqqLEGSSDRILELDQELR--KAERELSKAEKNSltetLKKEVKSLQNEKADLDRKLRKL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1141 QEDQQKL----WSVNETLHLEKERVSEEKQVAEKRYQQEHR---------DRESLVAEREKLLKEINAAQEELLKMHMEN 1207
Cdd:TIGR00606  521 DQEMEQLnhhtTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEltsllgyfpNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1208 DSLEASK----VSMQVLIEELRFCKDKLMAM--SEKARAEKEHLEGQVKKLTAENLVL----------VKDKDDVIQKLQ 1271
Cdd:TIGR00606  601 ASLEQNKnhinNELESKEEQLSSYEDKLFDVcgSQDEESDLERLKEEIEKSSKQRAMLagatavysqfITQLTDENQSCC 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1272 SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVK 1351
Cdd:TIGR00606  681 PVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1352 QLLSTEAETLRTQLDCASKALRKAELdmrqLQTSNSSLTKLLEEIKTCRAITDSECIQLlhEKESLAASERTLLAEKEEL 1431
Cdd:TIGR00606  761 QRLKNDIEEQETLLGTIMPEEESAKV----CLTDVTIMERFQMELKDVERKIAQQAAKL--QGSDLDRTVQQVNQEKQEK 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1432 LSENRIITEKLskqsEEVARLEMGLNEKITYLTSEkevaCQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGD 1511
Cdd:TIGR00606  835 QHELDTVVSKI----ELNRKLIQDQQEQIQHLKSK----TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKD 906

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1512 LRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKE-NQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIqakDNLN 1590
Cdd:TIGR00606  907 AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETEL---NTVN 983

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1591 AELKTCCCEKNMLLRDGLNLQE--ECQKLNEEIREIQQTL-ILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCS 1667
Cdd:TIGR00606  984 AQLEECEKHQEKINEDMRLMRQdiDTQKIQERWLQDNLTLrKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENI 1063

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 568937372  1668 EQL-QTENFTLTQEKTNSEQKV--EEIIKEKELLSAETAQLAANIE 1710
Cdd:TIGR00606 1064 DLIkRNHVLALGRQKGYEKEIKhfKKELREPQFRDAEEKYREMMIV 1109
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1026-1599 1.20e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.07  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1026 AKYEKASSETKTKHEEiLQNLQKMLADTE----DKLKAAQEANRDLMQDMEELKTQ-ADKAKSLTYLLTSAKKEIEVMSE 1100
Cdd:pfam12128  244 TKLQQEFNTLESAELR-LSHLHFGYKSDEtliaSRQEERQETSAELNQLLRTLDDQwKEKRDELNGELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1101 ELRGLKSEKQLYAQ---EANALKLEK-GSLLSKLIEVETKITLLQEDQQKLWSVNETLhlEKERVSEEKQVAEKRYQQEH 1176
Cdd:pfam12128  323 ELEALEDQHGAFLDadiETAAADQEQlPSWQSELENLEERLKALTGKHQDVTAKYNRR--RSKIKEQNNRDIAGIKDKLA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1177 RDREslvaEREKLLKEINA---AQEELLKMHMENDSLEASKVSMQVL--IEELRFCKDKLMAMSE-------------KA 1238
Cdd:pfam12128  401 KIRE----ARDRQLAVAEDdlqALESELREQLEAGKLEFNEEEYRLKsrLGELKLRLNQATATPElllqlenfderieRA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1239 RAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQE-----------IEDLTTEKKSAAEKQMSLDN 1307
Cdd:pfam12128  477 REEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELelqlfpqagtlLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1308 TCLTLK------------AERENLLQTNRDLQ--------FEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDC 1367
Cdd:pfam12128  557 PELLHRtdldpevwdgsvGGELNLYGVKLDLKridvpewaASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1368 ASK-------ALRKAELDMRQLQTSNSSLT-KLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRiiT 1439
Cdd:pfam12128  637 ASReetfartALKNARLDLRRLFDEKQSEKdKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREAR--T 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1440 EKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKyDQE 1519
Cdd:pfam12128  715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVR-RQE 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1520 ATNRRIVMQEKMKLlgNIDALKKELQERKKENQELtssKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCE 1599
Cdd:pfam12128  794 VLRYFDWYQETWLQ--RRPRLATQLSNIERAISEL---QQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE 868
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1421-2110 1.35e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 1.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1421 ERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLA 1500
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1501 DRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHT 1580
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1581 SMIQAKDNLNAELKTccCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLhgrvvLLEEEI 1660
Cdd:pfam02463  332 KEKEEIEELEKELKE--LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-----LKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1661 QRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELhscltkilddl 1740
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL----------- 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1741 rlnhEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKD 1820
Cdd:pfam02463  474 ----LKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1821 KSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEN--NLKTVEELNKSKEL 1898
Cdd:pfam02463  550 IVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLeaDEDDKRAKVVEGIL 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1899 LSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKD 1978
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1979 ADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSS 2058
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937372  2059 SSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALN 2110
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALE 841
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
427-956 1.39e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  427 LNQLEEEKRKVEDLQFRVEE-ESITKGDLEQKSPISEDPENTQTkleHARTKELEQsllfektKADKLQRELEDTRvatv 505
Cdd:PRK02224  161 LGKLEEYRERASDARLGVERvLSDQRGSLDQLKAQIEEKEEKDL---HERLNGLES-------ELAELDEEIERYE---- 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  506 SEKSRIMELEKDLALRAQEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDhqgemtslkehfgarEEAFQK 585
Cdd:PRK02224  227 EQREQARETRDEADEVLEEHEERREELET------------LEAEIEDLRETIAETERE---------------REELAE 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  586 EIKALHTATEKLSKENESLRSKLDHANKEnSDVIALWKSKLETAIASHQQAMEELKVSFSkgigtdsaefaELKTQIERL 665
Cdd:PRK02224  280 EVRDLRERLEELEEERDDLLAEAGLDDAD-AEAVEARREELEDRDEELRDRLEECRVAAQ-----------AHNEEAESL 347

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  666 RldyqHEIESLQSKQDSERSAhAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEikvKELE 745
Cdd:PRK02224  348 R----EDADDLEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRER----FGDAPVDLGNAE---DFLE 415

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  746 VLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKA-----------NSEGKLELETLRQQLEGAEKQIKNLETERNAES 814
Cdd:PRK02224  416 ELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEEVE 495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  815 SKANSItKELQEKElvltglqDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSEL 894
Cdd:PRK02224  496 ERLERA-EDLVEAE-------DRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA 567

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372  895 EKLRENLTDMEAKFKEKDDREDQLVKAKEKLE--NDIAEIMKMSGDNSSQLTKMNDELR--LKERS 956
Cdd:PRK02224  568 EEAREEVAELNSKLAELKERIESLERIRTLLAaiADAEDEIERLREKREALAELNDERRerLAEKR 633
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 334-975 1.60e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.57  E-value: 1.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   334 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDqlr 413
Cdd:pfam05483  159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   414 tmVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKspisedpentqTKLEHARTKELEQsllfektKADKL 493
Cdd:pfam05483  235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEK-----------TKLQDENLKELIE-------KKDHL 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   494 QRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSkppgdvdmslslLQEISALQEKLEAIHTDHQGEMTSLK 573
Cdd:pfam05483  295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQ------------MEELNKAKAAHSFVVTEFEATTCSLE 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   574 EHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIASHQQAMEELKVSFSKGI 648
Cdd:pfam05483  363 ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaEDEKLLDEKKQFEKIAEELKGKEQELI 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   649 G---TDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlv 725
Cdd:pfam05483  443 FllqAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ--- 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   726 emEDTLNKLQEAEIKVKELEVLQAKYT----EQSEVIGNFTSQLSAVKEKL---------LDLDALRKANSEGKLELE-- 790
Cdd:pfam05483  520 --EDIINCKKQEERMLKQIENLEEKEMnlrdELESVREEFIQKGDEVKCKLdkseenarsIEYEVLKKEKQMKILENKcn 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   791 TLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQ----VKETLEKELQTLKEKFASTSEEA 866
Cdd:pfam05483  598 NLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQkfeeIIDNYQKEIEDKKISEEKLLEEV 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   867 VSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDN-SSQLTK 945
Cdd:pfam05483  678 EKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNiKAELLS 757

                          650       660       670
                   ....*....|....*....|....*....|
gi 568937372   946 MNDELRLKERSVEELQLkltKANENASFLQ 975
Cdd:pfam05483  758 LKKQLEIEKEEKEKLKM---EAKENTAILK 784
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1031-2101 1.74e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.58  E-value: 1.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1031 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMeelKTQADKAKSLTYLLTSAKKEIEVMSEELRGlKSEKQ 1110
Cdd:pfam15921  128 AMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDS---NTQIEQLRKMMLSHEGVLQEIRSILVDFEE-ASGKK 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1111 LYAQEANALKLEK--GSLLSKLI-EVETKITLLQedqQKLWSVNETLhlekERVSEEKQVAEKRYQQEHRDR-ESLVAER 1186
Cdd:pfam15921  204 IYEHDSMSTMHFRslGSAISKILrELDTEISYLK---GRIFPVEDQL----EALKSESQNKIELLLQQHQDRiEQLISEH 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1187 EKllkEINAAQEELLKMHMENDSLEAskvsmqvlieelrfckdKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDV 1266
Cdd:pfam15921  277 EV---EITGLTEKASSARSQANSIQS-----------------QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1267 IQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAErenLLQTNRDLQFEKD-TLRQGQEKLSASLE 1345
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD---LHKREKELSLEKEqNKRLWDRDTGNSIT 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1346 ATLQVKQLLSTEAETLRtqLDCASKALR-----KAELDMRQLQTSNSSLTKLleeiktcraitDSECIQLLHEKESLAAS 1420
Cdd:pfam15921  414 IDHLRRELDDRNMEVQR--LEALLKAMKsecqgQMERQMAAIQGKNESLEKV-----------SSLTAQLESTKEMLRKV 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1421 ERTLLAEKEELLSENRIITEkLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLK---EKSALELQNGD 1497
Cdd:pfam15921  481 VEELTAKKMTLESSERTVSD-LTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQMAE 559

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1498 LLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLlgnidalKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEK 1577
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL-------EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLEL 632

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1578 EHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIReiqqtlILEKEARAKESETSLyENNKLhgrvvlle 1657
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE------VLKRNFRNKSEEMET-TTNKL-------- 697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1658 eEIQRLRVCSEQLQTENfTLTQEKTNSEQKVEEIIKEKELLSAETAQ---LAANIETLKSDFAALSKSKLELQELHSclt 1734
Cdd:pfam15921  698 -KMQLKSAQSELEQTRN-TLKSMEGSDGHAMKVAMGMQKQITAKRGQidaLQSKIQFLEEAMTNANKEKHFLKEEKN--- 772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1735 kilddlrlnhevALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEEsyFILQKEISQLAQTNSHIsanllesQSEN 1814
Cdd:pfam15921  773 ------------KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME--VALDKASLQFAECQDII-------QRQE 831

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1815 RTLRKDKSKLTLKIRELETlhsftAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQN---ELDTLKENNLKTVEE 1891
Cdd:pfam15921  832 QESVRLKLQHTLDVKELQG-----PGYTSNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHhsrKTNALKEDPTRDLKQ 906

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1892 LnkSKELLSVENQKMEEFKKEIETLKQAAAqksqqLSALQEenvklaeelgRTRDEVTSHQKLEEERSVLNNQLLEMKKR 1971
Cdd:pfam15921  907 L--LQELRSVINEEPTVQLSKAEDKGRAPS-----LGALDD----------RVRDCIIESSLRSDICHSSSNSLQTEGSK 969

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1972 ESE--FRKDADEEKASLQKSisltSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNlelql 2049
Cdd:pfam15921  970 SSEtcSREPVLLHAGELEDP----SSCFTFPSTASPSVKNSASRSFHSSPKKSPVHSLLTSSAEGSIGSSSQYRS----- 1040

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372  2050 kenKRQLSSSSGNTDAQAEEDERAQES----QQMIDFLNSVIVDLQRKNQDLKMKV 2101
Cdd:pfam15921 1041 ---AKTIHSPDSVKDSQSLPIETTGKTcrklQNRLESLQTLVEDLQLKNQAMSSMI 1093
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 788-994 1.88e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  788 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAV 867
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  868 SAQTRMQDTVNKLHQKEEQ----FNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:COG4942   101 AQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568937372  944 TKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAAR 994
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1235-2041 2.72e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 2.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1235 SEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKA 1314
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1315 ERENLLQTNRDLQFEKDTL-----RQGQEKLsasLEATLQVKQLLSTEAETLRTQLDcASKALRKAELDMRQLQTSNSSL 1389
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLgeeeqLRVKEKI---GELEAEIASLERSIAEKERELED-AEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1390 TKLLEEIKTCRAitdseciQLLHEKESLAASERTLLA----------------------------EKEELLSENRIITEK 1441
Cdd:TIGR02169  342 EREIEEERKRRD-------KLTEEYAELKEELEDLRAeleevdkefaetrdelkdyrekleklkrEINELKRELDRLQEE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1442 LSKQSEEVARLEM---GLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQ 1518
Cdd:TIGR02169  415 LQRLSEELADLNAaiaGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1519 EATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEA-------------QDAKKNLE--KEHTSMI 1583
Cdd:TIGR02169  495 AEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAagnrlnnvvveddAVAKEAIEllKRRKAGR 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1584 QAKDNLNaELKTCCCEKNMLLRDG-----LNLQEECQKLNEEIREI-QQTLILEKEARAKES---------ETSLYE--- 1645
Cdd:TIGR02169  575 ATFLPLN-KMRDERRDLSILSEDGvigfaVDLVEFDPKYEPAFKYVfGDTLVVEDIEAARRLmgkyrmvtlEGELFEksg 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1646 --------NNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDfa 1717
Cdd:TIGR02169  654 amtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE-- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1718 aLSKSKLELQELHSCLTKIlddlrlnhEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEK--LEESYFILQKEISQ 1795
Cdd:TIGR02169  732 -EEKLKERLEELEEDLSSL--------EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlSHSRIPEIQAELSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1796 LAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQImEQMTKEKTETLASLEDTKQTNARLQ 1875
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI-ENLNGKKEELEEELEELEAALRDLE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1876 NELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRT---RDEVTSHQ 1952
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQ 961

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1953 KLEEERSVL---NNQLLEMKKRESEFRKDADEEKASLQKSisltSALLTEKDAELEKLRNEVtVLRGENATAKSLHSVVQ 2029
Cdd:TIGR02169  962 RVEEEIRALepvNMLAIQEYEEVLKRLDELKEKRAKLEEE----RKAILERIEEYEKKKREV-FMEAFEAINENFNEIFA 1036

                          890
                   ....*....|..
gi 568937372  2030 TLESDKVKLELK 2041
Cdd:TIGR02169 1037 ELSGGTGELILE 1048
PTZ00121 PTZ00121
MAEBL; Provisional
 782-1592 3.46e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.84  E-value: 3.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  782 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFAS 861
Cdd:PTZ00121 1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEAR 1134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  862 TSEEAVSAQ-TRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNS 940
Cdd:PTZ00121 1135 KAEDARKAEeARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKA 1214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  941 SQLTKMNDELRLKE-RSVEELQLK---LTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKME- 1015
Cdd:PTZ00121 1215 EEARKAEDAKKAEAvKKAEEAKKDaeeAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADe 1294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1016 ----TSYNQCQDLKAKYEKA--SSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLT 1089
Cdd:PTZ00121 1295 akkaEEKKKADEAKKKAEEAkkADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1090 SAKKEIEVMSEelrglKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAE 1169
Cdd:PTZ00121 1375 EAKKKADAAKK-----KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1170 KRYQQEHRDRESLV--AEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVL--IEELRFCKDKLMAMSEKARAEKEHL 1245
Cdd:PTZ00121 1450 KKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkAAEAKKKADEAKKAEEAKKADEAKK 1529

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1246 EGQVKKLTAENLVLVKDKDDVIQKLqsayEELVKdqkalVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRD 1325
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKA----EELKK-----AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1326 LQFEKdtlRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDS 1405
Cdd:PTZ00121 1601 YEEEK---KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1406 ECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDsll 1485
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE--- 1754

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1486 KEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKllgNIDALKKELQERKKENQE-LTSSKCDLSLL 1564
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLvINDSKEMEDSA 1831

                         810       820
                  ....*....|....*....|....*...
gi 568937372 1565 LKEAQDAKKNLEKEHTSMIQAKDNLNAE 1592
Cdd:PTZ00121 1832 IKEVADSKNMQLEEADAFEKHKFNKNNE 1859
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1122-1866 3.52e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 3.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1122 EKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL 1201
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1202 KMHMENDSLEASKVSMQVLIEELRFCKDklmAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQ 1281
Cdd:TIGR00618  244 YLTQKREAQEEQLKKQQLLKQLRARIEE---LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1282 KALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQF-----EKDTLRQGQEKLSASLEATLQVKQLLST 1356
Cdd:TIGR00618  321 RSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIreiscQQHTLTQHIHTLQQQKTTLTQKLQSLCK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1357 EAETLRTQLDCASkALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENR 1436
Cdd:TIGR00618  401 ELDILQREQATID-TRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1437 IITEKLSKQSEEVARLEMGLNEKityltsEKEVACQKVAKLKKQQDSLLKEKSALELQNGDllaDRESSIKTIGDLRRKY 1516
Cdd:TIGR00618  480 QIHLQETRKKAVVLARLLELQEE------PCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE---QTYAQLETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1517 DQEATNRRIVMQEKMKLlgnidalkkELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKehtsmiqakdnlNAELKTC 1596
Cdd:TIGR00618  551 LTSERKQRASLKEQMQE---------IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK------------LSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1597 CCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVV--LLEEEIQRLRVCSEQLQTEN 1674
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIrvLPKELLASRQLALQKMQSEK 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1675 FTLTQEKtnseqkvEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEV 1754
Cdd:TIGR00618  690 EQLTYWK-------EMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1755 lQDNKNLLAEKREMMLRNEEALK-EKEKLEESYFILQKEISQL-AQTNSHISANLLESQSENRTLRKDKSKLTLKIREL- 1831
Cdd:TIGR00618  763 -HFNNNEEVTAALQTGAELSHLAaEIQFFNRLREEDTHLLKTLeAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKs 841

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 568937372  1832 ETLHSFTAAQTA-EDAMQIMEQMTKEKTETLASLED 1866
Cdd:TIGR00618  842 ATLGEITHQLLKyEECSKQLAQLTQEQAKIIQLSDK 877
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-849 3.87e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDqhvleleakmdqlrtmV 416
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAG----------------L 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  417 EAADREKVELlnQLEEEKRKVEDLQFRVEEESITKGDLeqkspisedpeNTQTKLEHARTKELEQSLLFEKTKADKLQRE 496
Cdd:PRK02224  305 DDADAEAVEA--RREELEDRDEELRDRLEECRVAAQAH-----------NEEAESLREDADDLEERAEELREEAAELESE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  497 LEDTRVATVSEKSRIMELEKdlalraqEVAELRRRLESSkpPGDVDMSLSLLQEisaLQEKLEAIHTDHQGEMTSLKEHF 576
Cdd:PRK02224  372 LEEAREAVEDRREEIEELEE-------EIEELRERFGDA--PVDLGNAEDFLEE---LREERDELREREAELEATLRTAR 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  577 GAREEAFQ--------------KEIKALHTATEKlSKENESLRSKLDHANKENSDVialwKSKLETA-----IASHQQAM 637
Cdd:PRK02224  440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEED-RERVEELEAELEDLEEEVEEV----EERLERAedlveAEDRIERL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  638 EELKVSFSKGIGTDSAEFAELKTQIERLRldyqHEIESLQSKQDSERSAHAKEMETMQAKLMKiIKEKEDSLEAVKARLD 717
Cdd:PRK02224  515 EERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREE-VAELNSKLAELKERIE 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  718 SAEDqhlveMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN--SEGKLELETLRQQ 795
Cdd:PRK02224  590 SLER-----IRTLLAAIADAE---DEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEY 661

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568937372  796 LEGAEKQIKNLETERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETLE 849
Cdd:PRK02224  662 LEQVEEKLDELREERDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
PRK11281 PRK11281
mechanosensitive channel MscK;
786-993 4.32e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.22  E-value: 4.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  786 KLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKeLVLTGLQDSLNQVNQvketlekELQTLKEKFASTSEE 865
Cdd:PRK11281   79 KEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLST-LSLRQLESRLAQTLD-------QLQNAQNDLAEYNSQ 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  866 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimKMSGDNSSQLTk 945
Cdd:PRK11281  151 LVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-------RKSLEGNTQLQ- 222

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 568937372  946 mndELRLKERsvEELQLKLTKANENASFLQKSIGEVTLkaEQSQQQAA 993
Cdd:PRK11281  223 ---DLLQKQR--DYLTARIQRLEHQLQLLQEAINSKRL--TLSEKTVQ 263
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
711-932 4.66e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  711 AVKARLDSAEDQ--HLVEMEDTLNKLQEaeiKVKELEVLQAKYTEqsevignftsqLSAVKEKLLDLDALRKAnsegkLE 788
Cdd:COG4913   222 DTFEAADALVEHfdDLERAHEALEDARE---QIELLEPIRELAER-----------YAAARERLAELEYLRAA-----LR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  789 LETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQV-NQVKETLEKELQTLKEKFastsEEAV 867
Cdd:COG4913   283 LWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLEREL----EERE 358

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937372  868 SAQTRMQDTVNKLHQK----EEQFNVLSSELEKLRENLTDMEAKFKEK----DDREDQLVKAKEKLENDIAEI 932
Cdd:COG4913   359 RRRARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEAlaeaEAALRDLRRELRELEAEIASL 431
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1565-2059 4.85e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 4.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1565 LKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTL------ILEKEARAKE 1638
Cdd:TIGR04523   49 LKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIkndkeqKNKLEVELNK 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1639 SETSLYENNKLHGRVVlleEEIQRLRVCSEQLQTENFTLTQEKTNSEqkveeiiKEKELLSAETAQLAANIETLKSDFAA 1718
Cdd:TIGR04523  129 LEKQKKENKKNIDKFL---TEIKKKEKELEKLNNKYNDLKKQKEELE-------NELNLLEKEKLNIQKNIDKIKNKLLK 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1719 LSKSKLELQ---ELHSCLTKILDDLRlNHEVALTERAEVLQDNKNllaEKREMMLRNEEALKE-KEKLEESYFILQKEIS 1794
Cdd:TIGR04523  199 LELLLSNLKkkiQKNKSLESQISELK-KQNNQLKDNIEKKQQEIN---EKTTEISNTQTQLNQlKDEQNKIKKQLSEKQK 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1795 QLAQTNSHIS---ANLLESQSENRTLRKDKSKLTLKireleTLHSFTAAQTAEdamqiMEQMTKEKTETLASLEDTKQTN 1871
Cdd:TIGR04523  275 ELEQNNKKIKeleKQLNQLKSEISDLNNQKEQDWNK-----ELKSELKNQEKK-----LEEIQNQISQNNKIISQLNEQI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1872 ARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL--------------KQAAAQKSQQLSALQEENVKL 1937
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLesqindleskiqnqEKLNQQKDEQIKKLQQEKELL 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1938 AEELGRTRDEVTSHQK----LEEERSVLNNQLLEMKKRESEFRKDADEEKAS---LQKSISLTSALLTEKDAELEKLRNE 2010
Cdd:TIGR04523  425 EKEIERLKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkIKQNLEQKQKELKSKEKELKKLNEE 504

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 568937372  2011 VTVLRGENATAK----SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 2059
Cdd:TIGR04523  505 KKELEEKVKDLTkkisSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE 557
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1677-1929 5.48e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 51.83  E-value: 5.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1677 LTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEvalTERAEVLQ 1756
Cdd:PLN02939  147 LNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGA---TEGLCVHS 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1757 DNKNLLAEKRE-MMLRNE-EALKEK----EKLEESYFILQKEISQLAQTNSHISANLLESQSenrtlrkDKSKL-TLKI- 1828
Cdd:PLN02939  224 LSKELDVLKEEnMLLKDDiQFLKAElievAETEERVFKLEKERSLLDASLRELESKFIVAQE-------DVSKLsPLQYd 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1829 ---RELETLHSF--TAAQTAEDAMQIMEQMT--KEKTETL-ASLEDTKQTnaRLQNELDTLKENNLKTVEE-LNKS-KEL 1898
Cdd:PLN02939  297 cwwEKVENLQDLldRATNQVEKAALVLDQNQdlRDKVDKLeASLKEANVS--KFSSYKVELLQQKLKLLEErLQASdHEI 374

                         250       260       270
                  ....*....|....*....|....*....|....
gi 568937372 1899 LS---VENQKMEEFKKEIETLKQAAAQKSQQLSA 1929
Cdd:PLN02939  375 HSyiqLYQESIKEFQDTLSKLKEESKKRSLEHPA 408
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 775-931 6.72e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 6.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  775 LDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKE--TLEKEL 852
Cdd:COG1579    19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKEI 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372  853 QTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLtdmEAKFKEKDDREDQLVKAKEKLENDIAE 931
Cdd:COG1579    99 ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL---DEELAELEAELEELEAEREELAAKIPP 174
PRK11281 PRK11281
mechanosensitive channel MscK;
1870-2087 7.41e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.45  E-value: 7.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1870 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1942
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1943 --RTRDEVTSHQKLEEERSVLNNQLLEMKKRESEfrkdADEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENAT 2020
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDLAE----YNSQLVSLQTQPERAQAALYANSQRLQQIRNL---LKGGKVG 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937372 2021 AKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEED---ERAQESQQMIDFLNSVI 2087
Cdd:PRK11281  186 GKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDyltARIQRLEHQLQLLQEAI 250
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1077-1301 7.51e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1077 QADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1156
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1157 EKERVSEE-KQVAEKRYQQEHRDRESLV---------AEREKLLKEINAAQEELLkmhmenDSLEASKVSMQVLIEELRF 1226
Cdd:COG4942    98 ELEAQKEElAELLRALYRLGRQPPLALLlspedfldaVRRLQYLKYLAPARREQA------EELRADLAELAALRAELEA 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372 1227 CKDKLMAMSEKARAEKEHLEgqvkKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEK 1301
Cdd:COG4942   172 ERAELEALLAELEEERAALE----ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
479-1070 8.71e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 8.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  479 LEQSLLFEKtkADKLQ---RELEDTRVATVSEKSRIMELE--KDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISA 553
Cdd:COG4913   218 LEEPDTFEA--ADALVehfDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  554 LQEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALHTATEKLSKEN-ESLRSKLDHANKEnsdvialwKSKLETAIAS 632
Cdd:COG4913   296 ELEELRAELARLEAELERLE----ARLDALREELDELEAQIRGNGGDRlEQLEREIERLERE--------LEERERRRAR 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  633 HQQAMEELKVSFSkgigTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKemetmqakLMKIIKEKEDSLEAV 712
Cdd:COG4913   364 LEALLAALGLPLP----ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD--------LRRELRELEAEIASL 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  713 KARlDSAEDQHLVEMEDTLNklQEAEIKVKEL----EVLQAKYTEQS-----E-VIGNFTSQLsAVKEKLLDlDALRKAN 782
Cdd:COG4913   432 ERR-KSNIPARLLALRDALA--EALGLDEAELpfvgELIEVRPEEERwrgaiErVLGGFALTL-LVPPEHYA-AALRWVN 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  783 SEgKLELetlRQQLEGAEKQIKNLETERnaesSKANSITKELQEKELVLTG-LQDSLNQVNQVK--ETLEkELQtlKEKF 859
Cdd:COG4913   507 RL-HLRG---RLVYERVRTGLPDPERPR----LDPDSLAGKLDFKPHPFRAwLEAELGRRFDYVcvDSPE-ELR--RHPR 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  860 ASTseeaVSAQTRMQDTvnkLHQK----------------EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKE 923
Cdd:COG4913   576 AIT----RAGQVKGNGT---RHEKddrrrirsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  924 KLEN---------DIAEIMKMSGDNSSQLTKM---NDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQ 991
Cdd:COG4913   649 ALQRlaeyswdeiDVASAEREIAELEAELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372  992 AARKHEEEKKELEEKLLELEkkmetsynqcQDLKAKYEKASSETKTKheEILQNLQKMLADTEDKLKAAQEANRDLMQD 1070
Cdd:COG4913   729 LDELQDRLEAAEDLARLELR----------ALLEERFAAALGDAVER--ELRENLEERIDALRARLNRAEEELERAMRA 795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1604-2008 1.21e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1604 LRDGLN-LQEECQKLNEEIREIQQTLILEKEARAKESETsLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKT 1682
Cdd:PRK02224  204 LHERLNgLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREELETLEAEIEDLRETIAETEREREELAEEVR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1683 NSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQElhSCLTKILDDLRLNHEV-ALTERAEVLQD-NKN 1760
Cdd:PRK02224  283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD--RLEECRVAAQAHNEEAeSLREDADDLEErAEE 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1761 LLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSfTAA 1840
Cdd:PRK02224  361 LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR-TAR 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1841 QTAEDAMQIMEQ-------MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQ------KME 1907
Cdd:PRK02224  440 ERVEEAEALLEAgkcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRierleeRRE 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1908 EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTS-HQKLEEERSVLNNqlLEMKKRESEFRKDADEEKASL 1986
Cdd:PRK02224  520 DLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEaEEEAEEAREEVAE--LNSKLAELKERIESLERIRTL 597

                         410       420
                  ....*....|....*....|..
gi 568937372 1987 QksisltsALLTEKDAELEKLR 2008
Cdd:PRK02224  598 L-------AAIADAEDEIERLR 612
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 690-1490 1.67e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 1.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   690 EMETMQAKLMKIIKEKEDSLEAVKARLDSAED---QHLVEMEDTLNKLQEAEIKVKELEVLQAKYteqsevignftsQLS 766
Cdd:pfam01576   58 EAEEMRARLAARKQELEEILHELESRLEEEEErsqQLQNEKKKMQQHIQDLEEQLDEEEAARQKL------------QLE 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   767 AV----KEKLLDLDALRKANSEGKLELEtlRQQLEgaeKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN 842
Cdd:pfam01576  126 KVtteaKIKKLEEDILLLEDQNSKLSKE--RKLLE---ERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   843 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAK 922
Cdd:pfam01576  201 KGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE---LQAALARLEEETAQKNNALKKIRELEAQISELQ 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   923 EKLENDIA---EIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEE 999
Cdd:pfam01576  278 EDLESERAarnKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1000 KKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-------------KHEEILQNLQKMLADTE-------DKLKA 1059
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTlqqakqdsehkrkKLEGQLQELQARLSESErqraelaEKLSK 437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1060 AQEANRDLMQDMEELKTQADK-AKSLTYLLTSAKKEIEVMSEELRglksEKQLYAQEANALKLEKGSLLSKLIEVETKit 1138
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKlSKDVSSLESQLQDTQELLQEETR----QKLNLSTRLRQLEDERNSLQEQLEEEEEA-- 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1139 lLQEDQQKLWSVNETLHLEKERVSEEKQVAE------KRYQQE----HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1208
Cdd:pfam01576  512 -KRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkKRLQRElealTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLD 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1209 S-------LEASKVSMQVLIEELRFCKDKLMAMSEKARAE---------------------KEHLEGQVKKLTAENLVLV 1260
Cdd:pfam01576  591 HqrqlvsnLEKKQKKFDQMLAEEKAISARYAEERDRAEAEareketralslaraleealeaKEELERTNKQLRAEMEDLV 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1261 KDKDDV------IQKLQSAYEELVKDQKALVQEIEDlttEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLR 1334
Cdd:pfam01576  671 SSKDDVgknvheLERSKRALEQQVEEMKTQLEELED---ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQL 747

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1335 QGQ-EKLSASLE-------ATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRA---IT 1403
Cdd:pfam01576  748 VKQvRELEAELEderkqraQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDeilAQ 827

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1404 DSEC--------IQLLHEKESLAASER---TLLAEKEELLSENRIITEKLSKQSEEVARLE---MGLNEKITYLTSEKEV 1469
Cdd:pfam01576  828 SKESekklknleAELLQLQEDLAASERarrQAQQERDELADEIASGASGKSALQDEKRRLEariAQLEEELEEEQSNTEL 907

                          890       900
                   ....*....|....*....|.
gi 568937372  1470 ACQKVAKLKKQQDSLLKEKSA 1490
Cdd:pfam01576  908 LNDRLRKSTLQVEQLTTELAA 928
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 834-1085 1.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  834 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 913
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  914 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMndeLRLKERSVEELQLKLTKanenasfLQKSIGEVTLKAEQSQQQAA 993
Cdd:COG4942   105 ELAELLRALYRLGRQPPLALLLSPEDFLDAVRR---LQYLKYLAPARREQAEE-------LRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  994 RKheeekkeleekllelekkmETSYNQCQDLKAKYEKAssetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEE 1073
Cdd:COG4942   175 EL-------------------EALLAELEEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|..
gi 568937372 1074 LKTQADKAKSLT 1085
Cdd:COG4942   232 LEAEAAAAAERT 243
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1764-2016 1.86e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1764 EKREMMLRNEEALKEKEKLEESYFILQKEISQLAQtnshisanLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1843
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIEL--------LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1844 EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveelnkskELLSVENQKMEEFKKEIETLKQAAAQK 1923
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEA-------------QIRGNGGDRLEQLEREIERLERELEER 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1924 SQQLSALQEENVKLAEELGRTRDEvtshqkleeersvlnnqLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAE 2003
Cdd:COG4913   358 ERRRARLEALLAALGLPLPASAEE-----------------FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                         250
                  ....*....|...
gi 568937372 2004 LEKLRNEVTVLRG 2016
Cdd:COG4913   421 LRELEAEIASLER 433
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1750-1977 2.37e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1750 ERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIR 1829
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1830 ELetlhsftaaqtaEDAMQIMEQMTKEKteTLASLEDTKQTNARLQNeLDTLKENNLKTVEELNKSKELLSVENQKMEEF 1909
Cdd:COG4942   108 EL------------LRALYRLGRQPPLA--LLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937372 1910 KKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSH-QKLEEERSVLNNQLLEMKKRESEFRK 1977
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAElAELQQEAEELEALIARLEAEAAAAAE 241
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 735-1236 2.58e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 49.36  E-value: 2.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   735 QEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAES 814
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   815 SKANSITKElqEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSEL 894
Cdd:pfam07111  143 EEIQRLHQE--QLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   895 EKLRENLTDM---EAKFKEKDDREDQLVKAKEKLENDIAEI---MKMSGDNSSQLTKM----NDELRLKERSVEELQLKL 964
Cdd:pfam07111  221 ESLRKYVGEQvppEVHSQTWELERQELLDTMQHLQEDRADLqatVELLQVRVQSLTHMlalqEEELTRKIQPSDSLEPEF 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   965 TKANEN--ASFLQKSIG-EVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQC-QDLKAKYEKASSETKT--- 1037
Cdd:pfam07111  301 PKKCRSllNRWREKVFAlMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRAlQDKAAEVEVERMSAKGlqm 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1038 ---KHEEILQNLQKMLADTEDKLK----AAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVmseeLRGLKSEKQ 1110
Cdd:pfam07111  381 elsRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHT----IKGLMARKV 456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1111 LYAQeanaLKLEKGSLLSKLIEVETKITLLQEDqqklwsvnetLHLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKL 1189
Cdd:pfam07111  457 ALAQ----LRQESCPPPPPAPPVDADLSLELEQ----------LREERNRLDAELQLSAHLIQQEvGRAREQGEAERQQL 522

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568937372  1190 LK-------EINAAQEELLKMHMEndsLEASKVSMQVLIEELRFCKDKLMAMSE 1236
Cdd:pfam07111  523 SEvaqqleqELQRAQESLASVGQQ---LEVARQGQQESTEEAASLRQELTQQQE 573
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1129-2056 3.06e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.66  E-value: 3.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1129 KLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAeKRYQQEhrdreslVAEREKLLKEINAAQEELLKMHMEND 1208
Cdd:TIGR00606  201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIV-KSYENE-------LDPLKNRLKEIEHNLSKIMKLDNEIK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1209 SLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKddvIQKLQSAYEELVKDQKALVQEI 1288
Cdd:TIGR00606  273 ALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRE---LEKLNKERRLLNQEKTELLVEQ 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1289 EDLTTEKKSAAEKQMSLDNTCLTLkAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCA 1368
Cdd:TIGR00606  350 GRLQLQADRHQEHIRARDSLIQSL-ATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQA 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1369 SKALRKAELDMRQLQTSNSSLTKLLEEIKTCRaitdseciqllHEKESLAASERTLLAEKEELLSENRiiteKLSKQSEe 1448
Cdd:TIGR00606  429 DEIRDEKKGLGRTIELKKEILEKKQEELKFVI-----------KELQQLEGSSDRILELDQELRKAER----ELSKAEK- 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1449 varlemglnekitylTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQ 1528
Cdd:TIGR00606  493 ---------------NSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1529 EKMKLLG------NIDALKKELQERKKEnqeltsskcdlsllLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknm 1602
Cdd:TIGR00606  558 HSDELTSllgyfpNKKQLEDWLHSKSKE--------------INQTRDRLAKLNKELASLEQNKNHINNELES------- 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1603 llrdglnLQEECQKLNEEIREI--QQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIqrlrvcsEQLQTENFT---L 1677
Cdd:TIGR00606  617 -------KEEQLSSYEDKLFDVcgSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFI-------TQLTDENQSccpV 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1678 TQEKTNSEQKVEEIIKEkelLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLrlnhEVALTERAEVLQD 1757
Cdd:TIGR00606  683 CQRVFQTEAELQEFISD---LQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLK----EKEIPELRNKLQK 755

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1758 NKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANllESQSENRTLRKDKSKLTLKIRELEtlhsf 1837
Cdd:TIGR00606  756 VNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDV--ERKIAQQAAKLQGSDLDRTVQQVN----- 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1838 taaQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLK 1917
Cdd:TIGR00606  829 ---QEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1918 QAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQ-KLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSAL 1996
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQdKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1997 LTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTlESDKVKLELKVKNLELQLKENKRQL 2056
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQDIDTQKIQERWLQD-NLTLRKRENELKEVEEELKQHLKEM 1044
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1602-2032 3.57e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 3.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1602 MLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEK 1681
Cdd:COG4717    46 MLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1682 TNSE--QKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL----TERAEVL 1755
Cdd:COG4717   126 QLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELqdlaEELEELQ 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1756 QDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQ-----KEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRE 1830
Cdd:COG4717   206 QRLAELEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1831 LETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEdtkqtnarLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFK 1910
Cdd:COG4717   286 LALLFLLLAREKASLGKEAEELQALPALEELEEEE--------LEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1911 KEIETLKQAAAQKSQQlSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEkaSLQKSI 1990
Cdd:COG4717   358 ELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--ELEEEL 434

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568937372 1991 SLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLE 2032
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 817-1398 4.04e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 4.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   817 ANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEK 896
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   897 LRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQK 976
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   977 SIGEVTLKAEQSQQ-----QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLA 1051
Cdd:TIGR04523  188 NIDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1052 DTEDKLKAAQEANRDLMQDMEELKT------------QADKAKSLTYLLTSAKKEIEVMSEELRG-------LKSEKQLY 1112
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQlkseisdlnnqkEQDWNKELKSELKNQEKKLEEIQNQISQnnkiisqLNEQISQL 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1113 AQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKE 1192
Cdd:TIGR04523  348 KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1193 INAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKD----KLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQ 1268
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTREsletQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1269 kLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAE--RENLLQTNRDLQFEKDTLRQGQEKLSASLEA 1346
Cdd:TIGR04523  508 -LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372  1347 TLQVKQLLSTE--------------AETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKT 1398
Cdd:TIGR04523  587 KQELIDQKEKEkkdlikeieekekkISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1536-2054 4.28e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 4.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1536 NIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCcceknmllrdgLNLQEECQ 1615
Cdd:PRK01156  184 NIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNEL-----------SSLEDMKN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1616 KLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLqtENFTLTQEKTNSE-QKVEEIIKE 1694
Cdd:PRK01156  253 RYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDI--ENKKQILSNIDAEiNKYHAIIKK 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1695 KELLSAETAQLaaniETLKSDFAALSKSKLELQELHS----------CLTKILDDLRLNHEVALTERAEVLqdnKNLLAE 1764
Cdd:PRK01156  331 LSVLQKDYNDY----IKKKSRYDDLNNQILELEGYEMdynsylksieSLKKKIEEYSKNIERMSAFISEIL---KIQEID 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1765 KREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHIS--ANLLESQS------------ENRTLRK----DKSKLTL 1826
Cdd:PRK01156  404 PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSrnMEMLNGQSvcpvcgttlgeeKSNHIINhyneKKSRLEE 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1827 KIRELETLHSfTAAQTAEDAMQIMEQMTKEKTETLAS----LEDTKQTNARLQNELDTLKENNLKTVEELNKSKEL-LSV 1901
Cdd:PRK01156  484 KIREIEIEVK-DIDEKIVDLKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLkLED 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1902 ENQKMEEFKK--------EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSH-QKLEEERSVLNNQ---LLEMK 1969
Cdd:PRK01156  563 LDSKRTSWLNalavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKyneIQENK 642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1970 KRESEFRKDADE------EKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENATAKSLHSVVQTLESDKVKLELKVK 2043
Cdd:PRK01156  643 ILIEKLRGKIDNykkqiaEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINELSDRIN 719

                         570
                  ....*....|.
gi 568937372 2044 NLELQLKENKR 2054
Cdd:PRK01156  720 DINETLESMKK 730
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 601-1918 4.93e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.89  E-value: 4.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   601 NESLRSKLDHANKENSDVIALWKsKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQ---IERLRLDYQHEIESLQ 677
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWK-KLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEiiyINKLKLELKEKIKNIS 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   678 SKQDSERSAhakemetmqAKLMKIIKEKEDSLEAVkARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSev 757
Cdd:TIGR01612  614 DKNEYIKKA---------IDLKKIIENNNAYIDEL-AKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELS-- 681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   758 ignftsqlSAVKEKLLDldalrkaNSEGKLELETLRQQLEGAEKQIKNLETE------RNAESSKANSITKELQEKELVL 831
Cdd:TIGR01612  682 --------SIVKENAID-------NTEDKAKLDDLKSKIDKEYDKIQNMETAtvelhlSNIENKKNELLDIIVEIKKHIH 746

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   832 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNklhQKEEQFNVLSSELEKLRENLTDMEAKFKEK 911
Cdd:TIGR01612  747 GEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKN---HYNDQINIDNIKDEDAKQNYDKSKEYIKTI 823

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   912 DDREDQLVKAKEKLENDIAEIMK-----MSGDNS---------SQLTKMNDELRlKERSVEELQLKLTKANENASFLQ-- 975
Cdd:TIGR01612  824 SIKEDEIFKIINEMKFMKDDFLNkvdkfINFENNckekidsehEQFAELTNKIK-AEISDDKLNDYEKKFNDSKSLINei 902

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   976 -KSIGEV------------TLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEI 1042
Cdd:TIGR01612  903 nKSIEEEyqnintlkkvdeYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKA 982

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1043 LQNLQkmLADTEDKlkaaqeaNRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEanalkle 1122
Cdd:TIGR01612  983 FKDAS--LNDYEAK-------NNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIE------- 1046

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1123 kgsllsklIEVETKITLLQEDQQKLWSVN-ETLHLE--KERVSEEKQVAEKRYQQEHRDRESLVAERE-KLLKEINAAQE 1198
Cdd:TIGR01612 1047 --------IAIHTSIYNIIDEIEKEIGKNiELLNKEilEEAEINITNFNEIKEKLKHYNFDDFGKEENiKYADEINKIKD 1118

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1199 ELLKMHMEND----SLEASKVSMQVLIEELRFCKDKLMAMSEKArAEKEHLEGQVKKLtaENLVLVKDKD----DVIQKL 1270
Cdd:TIGR01612 1119 DIKNLDQKIDhhikALEEIKKKSENYIDEIKAQINDLEDVADKA-ISNDDPEEIEKKI--ENIVTKIDKKkniyDEIKKL 1195

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1271 QSAYEELVKDQ------------------------------------KALVQEIEDLTTEKKSAAEKQMSLdNTCLTLKA 1314
Cdd:TIGR01612 1196 LNEIAEIEKDKtsleevkginlsygknlgklflekideekkksehmiKAMEAYIEDLDEIKEKSPEIENEM-GIEMDIKA 1274

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1315 ERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAEtlrtqLDCASKALRKAELDMrqlQTSNSSLTKLLE 1394
Cdd:TIGR01612 1275 EMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESD-----INDIKKELQKNLLDA---QKHNSDINLYLN 1346

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1395 EIKTCRAITDSECIQLLHE--KESLAASERTLLAEKEELLSenriiTEKLSKQSEEVARLEMgLNEKITYLTSEKEVAcQ 1472
Cdd:TIGR01612 1347 EIANIYNILKLNKIKKIIDevKEYTKEIEENNKNIKDELDK-----SEKLIKKIKDDINLEE-CKSKIESTLDDKDID-E 1419

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1473 KVAKLKKQQDSLLKEKSalelQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQ-EKMKLLGNIDALKKELQERKKEn 1551
Cdd:TIGR01612 1420 CIKKIKELKNHILSEES----NIDTYFKNADENNENVLLLFKNIEMADNKSQHILKiKKDNATNDHDFNINELKEHIDK- 1494

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1552 qeltSSKCDlslllKEAQDAKKNLEKEHTSMIQAKDNLNAELKTcccEKNMLLRDGLN-LQEECQKLNEEIREIQQTLIL 1630
Cdd:TIGR01612 1495 ----SKGCK-----DEADKNAKAIEKNKELFEQYKKDVTELLNK---YSALAIKNKFAkTKKDSEIIIKEIKDAHKKFIL 1562

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1631 ekearakESETSLYENNKLHGRVVLLEEEIQRLRVCSE-----QLQTENFTLTQEK-TNSEQKVEEIIKEKELLSAETAQ 1704
Cdd:TIGR01612 1563 -------EAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKaaidiQLSLENFENKFLKiSDIKKKINDCLKETESIEKKISS 1635

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1705 LAAN-------------------IETLKSDFAALSKSKLELQELHSCLTKILDDL---RLNHEVALTERAevlqdnknll 1762
Cdd:TIGR01612 1636 FSIDsqdtelkengdnlnslqefLESLKDQKKNIEDKKKELDELDSEIEKIEIDVdqhKKNYEIGIIEKI---------- 1705

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1763 aekremmlrNEEALKEKEKLEESYFILQKEISQLAqtnSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAqt 1842
Cdd:TIGR01612 1706 ---------KEIAIANKEEIESIKELIEPTIENLI---SSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAG-- 1771

                         1370      1380      1390      1400      1410      1420      1430
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372  1843 aedamqIMEQMTKEKTetlaSLEDTKQTNARLQNELdtlkennLKTVEELNKSKELLsvENQKMEEFKKEIETLKQ 1918
Cdd:TIGR01612 1772 ------CLETVSKEPI----TYDEIKNTRINAQNEF-------LKIIEIEKKSKSYL--DDIEAKEFDRIINHFKK 1828
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 402-1291 6.76e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 6.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   402 VLELEAKMDQLRTMVEA--ADREKVELLNQLEEEK--RKVEDLQFRVeeesitkgDLEQKSPISEDPENTQTKLEHArtk 477
Cdd:pfam12128  188 MHSKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQveHWIRDIQAIA--------GIMKIRPEFTKLQQEFNTLESA--- 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   478 ELEQSLLFEKTKADKLQRELEDTRVATVSE--KSRIMELEKDLAlraQEVAELRRRLESSKppgdvdmslsllQEISALQ 555
Cdd:pfam12128  257 ELRLSHLHFGYKSDETLIASRQEERQETSAelNQLLRTLDDQWK---EKRDELNGELSAAD------------AAVAKDR 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   556 EKLEAIHTDH----QGEMTSLKEH------FGAREEAFQKEIKALHTATEKLSKENESLRSKLDhanKENSDVIALWKSK 625
Cdd:pfam12128  322 SELEALEDQHgaflDADIETAAADqeqlpsWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   626 LE----------TAIASHQQAME-ELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhaKEMETM 694
Cdd:pfam12128  399 LAkireardrqlAVAEDDLQALEsELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD--ERIERA 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   695 QAKLMKIIKEKEDsLEAVKARLDSAEDQHLVemedtlnKLQEAEIKVKELEvlqakyteqsevignftSQLSAVKEKLLD 774
Cdd:pfam12128  477 REEQEAANAEVER-LQSELRQARKRRDQASE-------ALRQASRRLEERQ-----------------SALDELELQLFP 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   775 ldalrkanSEGKLeLETLRQQLEGAEKQI-KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVnQVKETLEKElQ 853
Cdd:pfam12128  532 --------QAGTL-LHFLRKEAPDWEQSIgKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRI-DVPEWAASE-E 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   854 TLKEKFASTSEEAVSAQTRMQdtvnklhQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIM 933
Cdd:pfam12128  601 ELRERLDKAEEALQSAREKQA-------AAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAL 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   934 KmsgdnssqltkmnDELRLKERSVEELqlkltkanenasflqksigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKK 1013
Cdd:pfam12128  674 A-------------ERKDSANERLNSL-------------------EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQ 721

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1014 METSYNQCQDLKAKYEKASSETKTKHEeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAksltylltsAKK 1093
Cdd:pfam12128  722 VVEGALDAQLALLKAAIAARRSGAKAE--LKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERI---------AVR 790

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1094 EIEVMSEElrglKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSvnetlHLEKERVSEEKqvaekryq 1173
Cdd:pfam12128  791 RQEVLRYF----DWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRA-----KLEMERKASEK-------- 853

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1174 QEHRDRESLVAEREkLLKEINAaqeelLKMHMENDSLEASKVSMQVLIEELrfcKDKLMAMSEKARAEKEHLEGQVKKLT 1253
Cdd:pfam12128  854 QQVRLSENLRGLRC-EMSKLAT-----LKEDANSEQAQGSIGERLAQLEDL---KLKRDYLSESVKKYVEHFKNVIADHS 924

                          890       900       910
                   ....*....|....*....|....*....|....*...
gi 568937372  1254 AENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1291
Cdd:pfam12128  925 GSGLAETWESLREEDHYQNDKGIRLLDYRKLVPYLEQW 962
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 466-991 8.17e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 8.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   466 NTQTKLEHARTKELEQSLLFEKTKADKL----------------------------QRELEDTRVATVSEKSRIMELEKD 517
Cdd:TIGR04523   74 NNKIKILEQQIKDLNDKLKKNKDKINKLnsdlskinseikndkeqknklevelnklEKQKKENKKNIDKFLTEIKKKEKE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   518 LALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHqgemtSLKEHFGAREEAFQKEIKALHTATEKL 597
Cdd:TIGR04523  154 LEKLNNKYNDLKKQKEELE-----NELNLLEKEKLNIQKNIDKIKNKL-----LKLELLLSNLKKKIQKNKSLESQISEL 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   598 SKENESLRSKLDHANKENSD---VIALWKSKLETAIASHQQAMEELK------VSFSKGIGTDSAEFAELKTQIERLRLD 668
Cdd:TIGR04523  224 KKQNNQLKDNIEKKQQEINEkttEISNTQTQLNQLKDEQNKIKKQLSekqkelEQNNKKIKELEKQLNQLKSEISDLNNQ 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   669 YQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDqhlvemeDTLNKLQEAEIKVKELEVLQ 748
Cdd:TIGR04523  304 KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSES-------ENSEKQRELEEKQNEIEKLK 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   749 AKYTEQSEVIGNFTSQLSAVKEKLLDLDalrKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKE 828
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESKIQNQE---KLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKE 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   829 LVLTGLQDSLNQVNQVKETLEKELQTLKekfastseeavsaqtrmqdtvNKLHQKEEQFNVLSSELEKLRENLTDMEAKF 908
Cdd:TIGR04523  454 LIIKNLDNTRESLETQLKVLSRSINKIK---------------------QNLEQKQKELKSKEKELKKLNEEKKELEEKV 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   909 KEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELR--LKERSVEELQLKLTKANENASFLQKSIGEVTLKAE 986
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592


                   ....*
gi 568937372   987 QSQQQ 991
Cdd:TIGR04523  593 QKEKE 597
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 427-981 9.20e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 9.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   427 LNQLEEEKRKVEDLQFRVEEESITK-GDLEQKSPISEDPENTQTKLEHARTKELEQSLLFEKT--KADKLQRELEDTRVA 503
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKeKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNidKIKNKLLKLELLLSN 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   504 TVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdmslsllQEISALQEKLEAIHTDHQgEMTSLKEHFGAREEAF 583
Cdd:TIGR04523  206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQ------------QEINEKTTEISNTQTQLN-QLKDEQNKIKKQLSEK 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   584 QKEIKALHTATEKLSKENESLRSKLDHANKENSDVialWKSKLETAIASHQQAMEELKVSFSKGIGTDSaefaELKTQIE 663
Cdd:TIGR04523  273 QKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQD---WNKELKSELKNQEKKLEEIQNQISQNNKIIS----QLNEQIS 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   664 RLRLDYQHeieslqskQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVK----------ARLDSAEDQHLVEMEDTLNK 733
Cdd:TIGR04523  346 QLKKELTN--------SESENSEKQRELEEKQNEIEKLKKENQSYKQEIKnlesqindleSKIQNQEKLNQQKDEQIKKL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   734 LQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN----SEGKLELETLRQQLEGAEKQIKnletE 809
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLetqlKVLSRSINKIKQNLEQKQKELK----S 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   810 RNAESSKANSITKELQEKELVLTGLQDSLN----QVNQVKETLEKELQTLKEKFAStseeavsaqtrmQDTVNKLHQKEE 885
Cdd:TIGR04523  494 KEKELKKLNEEKKELEEKVKDLTKKISSLKekieKLESEKKEKESKISDLEDELNK------------DDFELKKENLEK 561

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   886 QFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLT 965
Cdd:TIGR04523  562 EIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641

                          570
                   ....*....|....*.
gi 568937372   966 KANENASFLQKSIGEV 981
Cdd:TIGR04523  642 KLKQEVKQIKETIKEI 657
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1833-2058 1.05e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1833 TLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveELNKSKELLSVENQKMEEFKKE 1912
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-------RIAALARRIRALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1913 IETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISL 1992
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937372 1993 TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQLSS 2058
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAERqKLLARLEKELAELAAELAELQQEAEELEALIAR 231
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1360-2063 1.17e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.77  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1360 TLRTQLDCASKALRKAeldmRQLQTSNSSLTKLLEEIKTCRAItdseciqllHEKESLAASE-----RTLLAEKEELlsE 1434
Cdd:COG5022   759 YLRRRYLQALKRIKKI----QVIQHGFRLRRLVDYELKWRLFI---------KLQPLLSLLGsrkeyRSYLACIIKL--Q 823

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1435 NRIITEKLSKQSEEVARLEMGLNEKITYLTSEKevacqkvakLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRR 1514
Cdd:COG5022   824 KTIKREKKLRETEEVEFSLKAEVLIQKFGRSLK---------AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSI 894

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1515 KY--------DQEAT----NRRIVMQEKMKLLGNIDA-LKKELQERKKENQ---ELTSSKCDLSLL-----LKEAQDAKK 1573
Cdd:COG5022   895 SSlklvnlelESEIIelkkSLSSDLIENLEFKTELIArLKKLLNNIDLEEGpsiEYVKLPELNKLHeveskLKETSEEYE 974

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1574 NLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlILEKEARAKESETSLYENNKLHGRV 1653
Cdd:COG5022   975 DLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAE--LQSASKIISSESTELSILKPLQKLK 1052

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1654 VLLEEEIQRLRVCSEQLQTEN--------FTLTQEKTNSEQKVeeiIKEKELLSAETaQLAANIETLKSDFAALSKSKLE 1725
Cdd:COG5022  1053 GLLLLENNQLQARYKALKLRRensllddkQLYQLESTENLLKT---INVKDLEVTNR-NLVKPANVLQFIVAQMIKLNLL 1128

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1726 LQELHSCLTKILDdlrlnhevalteraevLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAqtNSHISA 1805
Cdd:COG5022  1129 QEISKFLSQLVNT----------------LEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQ--SALYDE 1190

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1806 NLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEdAMQIMEQMTKEKTETLASLEDTKQTNarlqneldtlkENN 1885
Cdd:COG5022  1191 KSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISE-GWVPTEYSTSLKGFNNLNKKFDTPAS-----------MSN 1258

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1886 LKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENV--KLAEELGRTRDEVtSHQKLEEERSVLNN 1963
Cdd:COG5022  1259 EKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLrwKSATEVNYNSEEL-DDWCREFEISDVDE 1337

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1964 QLLEMKKRESEFRKDadeeKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKslhSVVQTLESDKVKLELKVK 2043
Cdd:COG5022  1338 ELEELIQAVKVLQLL----KDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLPK---EILKKIEALLIKQELQLS 1410

                         730       740
                  ....*....|....*....|
gi 568937372 2044 NLELQLKENKRQLSSSSGNT 2063
Cdd:COG5022  1411 LEGKDETEVHLSEIFSEEKS 1430
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-535 1.17e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRT 414
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSPISEDP-------ENTQTKLEHARTKELEQSLLFEK 487
Cdd:COG4913   700 ELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAlleerfaAALGDAVERELRENLEERIDALR 779

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 568937372  488 TKADKLQRELEDTRVATVSE-KSRIMELEKDLAlRAQEVAELRRRLESS 535
Cdd:COG4913   780 ARLNRAEEELERAMRAFNREwPAETADLDADLE-SLPEYLALLDRLEED 827
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1157-1376 1.64e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1157 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckdklmamsE 1236
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR----------A 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1237 KARAEKEHLEGQVKKL----TAENLVLVKDKDDVIQKLQSA--YEELVKDQKalvQEIEDLTTEKKSAAEKQMSLDNTCL 1310
Cdd:COG4942    98 ELEAQKEELAELLRALyrlgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARR---EQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372 1311 TLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAE 1376
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 492-955 1.77e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  492 KLQRELEDTRVATVSEKSRIMELEKDLAlraqEVAELRRRLESskppgDVDMS---LSLLQEISALQEKLEAIHTDhQGE 568
Cdd:COG3096   289 ELRRELFGARRQLAEEQYRLVEMARELE----ELSARESDLEQ-----DYQAAsdhLNLVQTALRQQEKIERYQED-LEE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  569 MTS-LKEHFGAREEAfQKEIKALHTATEKLSKENESLRSKLdhankensdvialwkskletaiASHQQAMEELkvsfskg 647
Cdd:COG3096   359 LTErLEEQEEVVEEA-AEQLAEAEARLEAAEEEVDSLKSQL----------------------ADYQQALDVQ------- 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  648 igtdsaefaelktqiERLRLDYQheiESLQSKQDSERSAHAKEMETMQAklmkiikekEDSLEAVKARLDSAeDQHLVEM 727
Cdd:COG3096   409 ---------------QTRAIQYQ---QAVQALEKARALCGLPDLTPENA---------EDYLAAFRAKEQQA-TEEVLEL 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  728 EDTLNKLQEAEI---KVKELEVLQAKYTEQSEVIGNFTSQLSAVKEklLDLDALRKANSEGKL-ELETLRQQLEGAEKQI 803
Cdd:COG3096   461 EQKLSVADAARRqfeKAYELVCKIAGEVERSQAWQTARELLRRYRS--QQALAQRLQQLRAQLaELEQRLRQQQNAERLL 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  804 KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEA---VSAQTRMQDTVNKL 880
Cdd:COG3096   539 EEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARApawLAAQDALERLREQS 618

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372  881 HQKEEQFNVLSSELEKLRENLTDMEAKfkekddrEDQLVKAKEKLENDIAEIMKMSGDNSSQLtkmndeLRLKER 955
Cdd:COG3096   619 GEALADSQEVTAAMQQLLEREREATVE-------RDELAARKQALESQIERLSQPGGAEDPRL------LALAER 680
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2133-2150 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 568937372  2133 RLFCDICDCFDlHDTEDC 2150
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 584-1263 3.13e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.87  E-value: 3.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   584 QKEIKALHTATEKLSKENESLRSKLDHANKENSDVIA------LWKSKLETAIAS----------HQQAMEELKVSFSKG 647
Cdd:pfam05483  112 RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNN 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   648 IGTDSAEFAELKTQIERLRLDYQHEIeslqsKQDSERSAHAKEmetmqaKLMKIIKEKEDSLEAVKARLDSAEDQhlveM 727
Cdd:pfam05483  192 IEKMILAFEELRVQAENARLEMHFKL-----KEDHEKIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----M 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   728 EDTLNKLQEAEIKVKELEvlqAKYTEQSEVIGNFTSQLSAVKEKLLDLD-ALRKANSEGKleleTLRQQLEGAEKQIKNL 806
Cdd:pfam05483  257 KDLTFLLEESRDKANQLE---EKTKLQDENLKELIEKKDHLTKELEDIKmSLQRSMSTQK----ALEEDLQIATKTICQL 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   807 ETERNAESSKANsitKELQEKELVLTGLQDSLNqvnqvkeTLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ 886
Cdd:pfam05483  330 TEEKEAQMEELN---KAKAAHSFVVTEFEATTC-------SLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   887 FNVLSSELEKLRENLTDMEAKFKEKDDRE---DQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 963
Cdd:pfam05483  400 KNNKEVELEELKKILAEDEKLLDEKKQFEkiaEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   964 LTKANENASFLQKSIGEVTLKAEQSQQQAArKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEIL 1043
Cdd:pfam05483  480 LEKEKLKNIELTAHCDKLLLENKELTQEAS-DMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFI 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1044 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSE-----KQLYAQE--A 1116
Cdd:pfam05483  559 QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKgsaenKQLNAYEikV 638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1117 NALKLEKGSLLSKLIEV----ETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKE 1192
Cdd:pfam05483  639 NKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDK 718

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372  1193 INAAQEELLKMHMENDSLEAS-KVSMQVlieELRFCKDKLMAMSEKARAEKEHLEgQVKKLTAENLVLVKDK 1263
Cdd:pfam05483  719 IIEERDSELGLYKNKEQEQSSaKAALEI---ELSNIKAELLSLKKQLEIEKEEKE-KLKMEAKENTAILKDK 786
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1619-2046 3.17e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 3.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1619 EEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELL 1698
Cdd:PRK02224  289 EELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAEL 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1699 SAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEA--L 1776
Cdd:PRK02224  369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAeaL 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1777 KEKEKLEESYFILqkEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTA--------AQTAEDAMQ 1848
Cdd:PRK02224  449 LEAGKCPECGQPV--EGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDrierleerREDLEELIA 526

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1849 IMEQMTKEKTETLASLEDTKQtnaRLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQ------AAAQ 1922
Cdd:PRK02224  527 ERRETIEEKRERAEELRERAA---ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtllaAIAD 603

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1923 KSQQLSALQEENVKLAE--ELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRK----------DADEEKASLQKSI 1990
Cdd:PRK02224  604 AEDEIERLREKREALAElnDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEyleqveekldELREERDDLQAEI 683

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372 1991 sltsALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLES--DKVKLELKVKNLE 2046
Cdd:PRK02224  684 ----GAVENELEELEELRERREALENRVEALEALYDEAEELESmyGDLRAELRQRNVE 737
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1267-1730 4.61e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1267 IQKLQSAYEELVKDQ----KALVQEIEDLTTEKKSAAEKQmsldntcltlkAERENLLQTNRDLQFEKDTLRQGQEKLSA 1342
Cdd:COG4717    48 LERLEKEADELFKPQgrkpELNLKELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELRE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1343 SLEATLQVKQLLST--EAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKEslaAS 1420
Cdd:COG4717   117 ELEKLEKLLQLLPLyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EE 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1421 ERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEVAcQKVAKLKKQQDSLLKEKSALELQ-NGDLL 1499
Cdd:COG4717   194 LQDLAEELEELQQRLAELEEELEEAQEELEELE----EELEQLENELEAA-ALEERLKEARLLLLIAAALLALLgLGGSL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1500 ADRESSIKTIGDL-------------RRKYDQEATNRRIVMQEKMKLLGNIDaLKKELQERKKENQELTSSKCDLSLLLK 1566
Cdd:COG4717   269 LSLILTIAGVLFLvlgllallflllaREKASLGKEAEELQALPALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIE 347

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1567 EAQDAKKNLEKEHTSM--IQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLY 1644
Cdd:COG4717   348 ELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE 427

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1645 ENnkLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTN--SEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKS 1722
Cdd:COG4717   428 EE--LEEELEELEEELEELEEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAEEWAALKLALELLEEA 505


                  ....*...
gi 568937372 1723 KLELQELH 1730
Cdd:COG4717   506 REEYREER 513
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1749-2102 4.64e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 4.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1749 TERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKI 1828
Cdd:PRK02224  213 SELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1829 RELETLHSFTAAQT------AEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVE------------ 1890
Cdd:PRK02224  289 EELEEERDDLLAEAglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEEraeelreeaael 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1891 --ELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQ-KLEEERSVL--NNQL 1965
Cdd:PRK02224  369 esELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVeeAEAL 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1966 LEMKKRESEFRKDADEEKASlqkSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNL 2045
Cdd:PRK02224  449 LEAGKCPECGQPVEGSPHVE---TIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELI 525

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372 2046 ELQ---LKENKRQLSSS---SGNTDAQAEE-DERAQESQQMIDFLNSVIVDLQRKNQDLKMKVE 2102
Cdd:PRK02224  526 AERretIEEKRERAEELrerAAELEAEAEEkREAAAEAEEEAEEAREEVAELNSKLAELKERIE 589
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1610-2102 4.83e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1610 LQEECQKLNEEIREIQQTLILEKEARAKESETslyennklhgRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVE 1689
Cdd:COG4913   257 IRELAERYAAARERLAELEYLRAALRLWFAQR----------RLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1690 EIikEKELLSAETAQlaanIETLKSDFAALSKSKLELQELHSCLTKILDDLRL---NHEVALTERAEVLQDNKNLLAEKR 1766
Cdd:COG4913   327 EL--EAQIRGNGGDR----LEQLEREIERLERELEERERRRARLEALLAALGLplpASAEEFAALRAEAAALLEALEEEL 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1767 EmMLRNE--EALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSE-NRTLRKDKSKLT-----LKIRELE------ 1832
Cdd:COG4913   401 E-ALEEAlaEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAlAEALGLDEAELPfvgelIEVRPEEerwrga 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1833 ---TLHSF-----------TAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAR-LQNELDTlKENNLKT--VEELNKS 1895
Cdd:COG4913   480 ierVLGGFaltllvppehyAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDsLAGKLDF-KPHPFRAwlEAELGRR 558

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1896 KELLSVENQkmEEFKKE--------------------------------------IETLKQAAAQKSQQLSALQEENVKL 1937
Cdd:COG4913   559 FDYVCVDSP--EELRRHpraitragqvkgngtrhekddrrrirsryvlgfdnrakLAALEAELAELEEELAEAEERLEAL 636

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1938 AEELGRTRDEVTSHQKLEEersvLNNQLLEMKKRESEFRkDADEEKASLQKSisltSALLTEKDAELEKLRNEVTVLRGE 2017
Cdd:COG4913   637 EAELDALQERREALQRLAE----YSWDEIDVASAEREIA-ELEAELERLDAS----SDDLAALEEQLEELEAELEELEEE 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2018 natakslhsvVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEE--DERAQE------SQQMIDFLNSVIVD 2089
Cdd:COG4913   708 ----------LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAllEERFAAalgdavERELRENLEERIDA 777

                         570
                  ....*....|...
gi 568937372 2090 LQRKNQDLKMKVE 2102
Cdd:COG4913   778 LRARLNRAEEELE 790
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
915-1352 5.02e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 5.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  915 EDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGE----VTLKAEQSQQ 990
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEElreeLEKLEKLLQL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  991 QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQD 1070
Cdd:COG4717   128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1071 MEELKTQADKAKSltyLLTSAKKEIEVMSEELRGLKSEKQLYAQEAN--------ALKLEKGSLLSKLIEVETKITLLQE 1142
Cdd:COG4717   208 LAELEEELEEAQE---ELEELEEELEQLENELEAAALEERLKEARLLlliaaallALLGLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1143 DQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSM--QVL 1220
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1221 IEELRFCKDKLMAMS------------------EKARAEKEHLEGQVKKLTAENLVLVKDKDDviQKLQSAYEELVKDQK 1282
Cdd:COG4717   365 LEELEQEIAALLAEAgvedeeelraaleqaeeyQELKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELE 442

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372 1283 ALVQEIEDLTTEKKSAAE--KQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQ 1352
Cdd:COG4717   443 ELEEELEELREELAELEAelEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
846-964 7.43e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 7.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  846 ETLEKELQTLKEKfaSTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDR----EDQLVKA 921
Cdd:COG2433   376 LSIEEALEELIEK--ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERierlERELSEA 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568937372  922 KEKLENDI---AEIMKMSGDNsSQLTKmndELRLKERSVEELQLKL 964
Cdd:COG2433   454 RSEERREIrkdREISRLDREI-ERLER---ELEEERERIEELKRKL 495
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 404-1629 8.36e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.04  E-value: 8.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   404 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV------------EEESITKGDLEQKSP---ISEDPENTQ 468
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIkdlfdkyleiddEIIYINKLKLELKEKiknISDKNEYIK 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   469 TKLEHARTKELEQSLLFEKTKADKLQ----RELEDTRVATV-SEKSRIME-----LEKDLALRAQEVA----ELRRRLES 534
Cdd:TIGR01612  621 KAIDLKKIIENNNAYIDELAKISPYQvpehLKNKDKIYSTIkSELSKIYEddidaLYNELSSIVKENAidntEDKAKLDD 700

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   535 SKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEhfgAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKE 614
Cdd:TIGR01612  701 LKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVE---IKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKE 777

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   615 NsDVIALWKSKLetaiashqqamEELKVSFSKGIGTDSAEFAELKTQIERLRldyqHEIESLQSKQDsERSAHAKEMETM 694
Cdd:TIGR01612  778 K-DELNKYKSKI-----------SEIKNHYNDQINIDNIKDEDAKQNYDKSK----EYIKTISIKED-EIFKIINEMKFM 840

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   695 QAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQeAEIKVKELEVLQAKYTEQSEVIGNFTsqlSAVKEKLLD 774
Cdd:TIGR01612  841 KDDFLNKVDKFINFENNCKEKIDSEHEQ----FAELTNKIK-AEISDDKLNDYEKKFNDSKSLINEIN---KSIEEEYQN 912

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   775 LDALRKANSEGKL------ELETLR-QQLEGAEKQIKNLETERNAESSKA-------NSITKELQEKELVLTGLqdSLNQ 840
Cdd:TIGR01612  913 INTLKKVDEYIKIcentkeSIEKFHnKQNILKEILNKNIDTIKESNLIEKsykdkfdNTLIDKINELDKAFKDA--SLND 990

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   841 VNQVKETLEKELQTLKEKFASTSEEAVSAQtrmqdtvnkLHQKEEQFNVLSSELEKLRENLTDME-----AKFKEKDDRE 915
Cdd:TIGR01612  991 YEAKNNELIKYFNDLKANLGKNKENMLYHQ---------FDEKEKATNDIEQKIEDANKNIPNIEiaihtSIYNIIDEIE 1061

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   916 DQLVKAKEKLENdiaEIMKMSGDNSSQLTKMNDELRLKERS--VEELQLKLTkanENASFLQKSIGEVtlkaeqsqQQAA 993
Cdd:TIGR01612 1062 KEIGKNIELLNK---EILEEAEINITNFNEIKEKLKHYNFDdfGKEENIKYA---DEINKIKDDIKNL--------DQKI 1127

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   994 RKHEEEKKELEEKLLELEKKMETSYNQCQDL--KAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrdlMQDM 1071
Cdd:TIGR01612 1128 DHHIKALEEIKKKSENYIDEIKAQINDLEDVadKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNE-----IAEI 1202

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1072 EELKTQADKAK--SLTYLLTSAKKEIEVMSEELRglKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWS 1149
Cdd:TIGR01612 1203 EKDKTSLEEVKgiNLSYGKNLGKLFLEKIDEEKK--KSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFN 1280

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1150 VNETLHlekervseekqvaEKRYQQEHRDRESLVAEREKLLK---------EINAAQEELLK------MHMENDSLEASK 1214
Cdd:TIGR01612 1281 ISHDDD-------------KDHHIISKKHDENISDIREKSLKiiedfseesDINDIKKELQKnlldaqKHNSDINLYLNE 1347

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1215 VSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTE 1294
Cdd:TIGR01612 1348 IANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDIDECIKKIKEL 1427

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1295 KKSAAEKQMSLDNTCLTLKAEREN--LLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLST--EAETLRTQLDCASK 1370
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNADENNENvlLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHidKSKGCKDEADKNAK 1507

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1371 ALRKAELDMRQLQtsnSSLTKLLE-----EIKTCRAITDSECIQLLHEKESlAASERTLLAEKEElLSENRIITEKLSKQ 1445
Cdd:TIGR01612 1508 AIEKNKELFEQYK---KDVTELLNkysalAIKNKFAKTKKDSEIIIKEIKD-AHKKFILEAEKSE-QKIKEIKKEKFRIE 1582

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1446 sEEVARLEMGLNEKITYLTSEK--EVACQKVAKLKKQQDSLLKEKSALELQNGDLLAD-RESSIKTIGDLR---RKYDQE 1519
Cdd:TIGR01612 1583 -DDAAKNDKSNKAAIDIQLSLEnfENKFLKISDIKKKINDCLKETESIEKKISSFSIDsQDTELKENGDNLnslQEFLES 1661

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1520 ATNRRIVMQEKMKLLGNIDALKKELQ---ERKKENQEltsskcdLSLLLKEAQDAKKNLEKEHTSmiqaKDNLNAELKTC 1596
Cdd:TIGR01612 1662 LKDQKKNIEDKKKELDELDSEIEKIEidvDQHKKNYE-------IGIIEKIKEIAIANKEEIESI----KELIEPTIENL 1730

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 568937372  1597 CCEKNMLLRDGLNLQEECQKLNEEIREIQQTLI 1629
Cdd:TIGR01612 1731 ISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFI 1763
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1037-1569 8.42e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 8.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1037 TKHEEILQNLQKMLADTEDKLKAAQEANRdlMQDmEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEA 1116
Cdd:pfam05483  250 TEKENKMKDLTFLLEESRDKANQLEEKTK--LQD-ENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTI 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1117 NALKLEKGSLLSKLIEVETKITLL-QEDQQKLWSVNETLHLEKERVsEEKQVAEKRYQQEHRDRESLVAEREKLLKEINA 1195
Cdd:pfam05483  327 CQLTEEKEAQMEELNKAKAAHSFVvTEFEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEV 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1196 AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQ---- 1271
Cdd:pfam05483  406 ELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEkekl 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1272 ------SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLE 1345
Cdd:pfam05483  486 knieltAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVK 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1346 ATLQVKQLLSTEAETLRTQLDCASKALRKAELDMR-QLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTL 1424
Cdd:pfam05483  566 CKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKkQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELEL 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1425 LAEKEELLSenriITEKLSKQSEEVARLEMGLNEKItyltSEKEVACQKVAKLKKQQDSLLKEKSALEL--------QNG 1496
Cdd:pfam05483  646 ASAKQKFEE----IIDNYQKEIEDKKISEEKLLEEV----EKAKAIADEAVKLQKEIDKRCQHKIAEMValmekhkhQYD 717

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937372  1497 DLLADRESSIktigDLRRKYDQEATNRRIVMQEKMKLLGN-IDALKKELQERKKENQELTSSKCDLSLLLKEAQ 1569
Cdd:pfam05483  718 KIIEERDSEL----GLYKNKEQEQSSAKAALEIELSNIKAeLLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1156-1366 8.73e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 8.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1156 LEKERVSEEKQVAEKRYQQEHRDRESLVAEREK--LLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFckDKLMA 1233
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQieLLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL--ELLEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1234 MSEKARAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKA-LVQEIEDLTTEKKSAAEKQMSLDNTC--- 1309
Cdd:COG4913   296 ELEELRAELARLEAELERLEAR----LDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARLEALLaal 371

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372 1310 -LTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLD 1366
Cdd:COG4913   372 gLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA 429
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1609-1946 1.00e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.12  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1609 NLQEECQKlneEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKV 1688
Cdd:pfam07888   34 NRLEECLQ---ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1689 EEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQelhscltkilddlrlnhevalTERAEVLQDNKNLLAEKREM 1768
Cdd:pfam07888  111 EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERE---------------------TELERMKERAKKAGAQRKEE 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1769 MLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHS-FTAAQTAEDAM 1847
Cdd:pfam07888  170 EAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEeLRSLQERLNAS 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1848 QIMEQMTKEKTETLASLEDTKQTN---ARLQNELDTLK--ENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQ 1922
Cdd:pfam07888  250 ERKVEGLGEELSSMAAQRDRTQAElhqARLQAAQLTLQlaDASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQR 329

                          330       340
                   ....*....|....*....|....
gi 568937372  1923 KSQQLSALQEENVKLAEELGRTRD 1946
Cdd:pfam07888  330 LEERLQEERMEREKLEVELGREKD 353
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
816-1175 1.18e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  816 KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELE 895
Cdd:COG4372    11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  896 KLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQ 975
Cdd:COG4372    91 AAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  976 KSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTED 1055
Cdd:COG4372   171 QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1056 KLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVET 1135
Cdd:COG4372   251 LLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLEL 330

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 568937372 1136 KITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQE 1175
Cdd:COG4372   331 ALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1142-1454 1.25e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1142 EDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEEllkmhmendsleaskvsmqVLI 1221
Cdd:PLN02939  114 EQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGK-------------------INI 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1222 EELRFCK-DKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAE 1300
Cdd:PLN02939  175 LEMRLSEtDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAE 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1301 KqmslDNTCLTLKAERENLLQTNRDLQFekdTLRQGQEKLSASleATLQVKQLLStEAETLRTQLDCASKALRKAELDMR 1380
Cdd:PLN02939  255 T----EERVFKLEKERSLLDASLRELES---KFIVAQEDVSKL--SPLQYDCWWE-KVENLQDLLDRATNQVEKAALVLD 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1381 QLQTSNSSLTKL---LEEIKTCRaiTDSECIQLLHEKesLAASERTLLAEKEELLSENRI-------ITEKLSKQSEEVA 1450
Cdd:PLN02939  325 QNQDLRDKVDKLeasLKEANVSK--FSSYKVELLQQK--LKLLEERLQASDHEIHSYIQLyqesikeFQDTLSKLKEESK 400


                  ....
gi 568937372 1451 RLEM 1454
Cdd:PLN02939  401 KRSL 404
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 689-1173 1.34e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   689 KEMETMQAKLMKIIKEKEDSLEAVKARLDSAED---QHLVEMEDTlnklQEAEIKVKELEVLQAKYTEQSEVIGNFTSQ- 764
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlqGQLAHAKKQ----QELQQRYAELCAAAITCTAQCEKLEKIHLQe 463

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   765 ----LSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANsitkELQEKELVLTGLQDSLNQ 840
Cdd:TIGR00618  464 saqsLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID----NPGPLTRRMQRGEQTYAQ 539

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   841 VNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREnLTDMEAKFKEKDDREDQLVK 920
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD-LTEKLSEAEDMLACEQHALL 618

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   921 AKEKLENDIAEImkmsgdnSSQLTKMNDELRLKERSVEELQLKLTKANENASFL--------QKSIGEVTLKAEQSQQQA 992
Cdd:TIGR00618  619 RKLQPEQDLQDV-------RLHLQQCSQELALKLTALHALQLTLTQERVREHALsirvlpkeLLASRQLALQKMQSEKEQ 691

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   993 ARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDME 1072
Cdd:TIGR00618  692 LTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1073 ELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKliEVETKITLLQEDQQKLWSVNE 1152
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQ--EEEQFLSRLEEKSATLGEITH 849

                          490       500
                   ....*....|....*....|.
gi 568937372  1153 TLHLEKERVSEEKQVAEKRYQ 1173
Cdd:TIGR00618  850 QLLKYEECSKQLAQLTQEQAK 870
COG5022 COG5022
Myosin heavy chain [General function prediction only];
794-1159 1.39e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.91  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  794 QQLEGAEKQIKNLETErNAESSKANSITKELQEKELVLT-GLQDSLNQVNQVKETLEKELQTLKEKfaSTSEEAVSAQTR 872
Cdd:COG5022   875 QRVELAERQLQELKID-VKSISSLKLVNLELESEIIELKkSLSSDLIENLEFKTELIARLKKLLNN--IDLEEGPSIEYV 951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  873 MQDTVNKLHQKEeqfnvlsSELEKLRENLTDMeakFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSqLTKMNDELRL 952
Cdd:COG5022   952 KLPELNKLHEVE-------SKLKETSEEYEDL---LKKSTILVREGNKANSELKNFKKELAELSKQYGA-LQESTKQLKE 1020

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  953 KERSVEELQLKLTKANENASFL------QKSIGEVTLKAEQSQQQAarKHEEEKKELEEKLLELEKKMETSYNQCQDLKA 1026
Cdd:COG5022  1021 LPVEVAELQSASKIISSESTELsilkplQKLKGLLLLENNQLQARY--KALKLRRENSLLDDKQLYQLESTENLLKTINV 1098

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1027 KYEKASSETKTKHEEILQNLQKMLADTeDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLK 1106
Cdd:COG5022  1099 KDLEVTNRNLVKPANVLQFIVAQMIKL-NLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAAL 1177

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568937372 1107 SEKQLYaqEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVN-ETLHLEKE 1159
Cdd:COG5022  1178 SEKRLY--QSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGdKLKKLISE 1229
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1872-2017 1.46e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1872 ARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRD--EVT 1949
Cdd:COG1579    13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEYE 92

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937372 1950 SHQK----LEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 2017
Cdd:COG1579    93 ALQKeiesLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
766-1096 1.55e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  766 SAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVK 845
Cdd:COG4372    31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  846 ETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREdqLVKAKEKL 925
Cdd:COG4372   111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE--AEQALDEL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  926 ENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 1005
Cdd:COG4372   189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1006 KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLT 1085
Cdd:COG4372   269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348

                         330
                  ....*....|.
gi 568937372 1086 YLLTSAKKEIE 1096
Cdd:COG4372   349 GLLDNDVLELL 359
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1678-1940 1.60e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1678 TQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHScltkilddlrlnhevALTERAEVLQD 1757
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR---------------ALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1758 NKNLLAEKREMMLRNEEALKEKekleesyfiLQKEISQLAQTNSHISANLLESQSENRTLrkdkskltlkIRELETLHSF 1837
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEE---------LAELLRALYRLGRQPPLALLLSPEDFLDA----------VRRLQYLKYL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1838 TAAQtaedaMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLK 1917
Cdd:COG4942   145 APAR-----REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219

                         250       260
                  ....*....|....*....|...
gi 568937372 1918 QAAAQKSQQLSALQEENVKLAEE 1940
Cdd:COG4942   220 QEAEELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1024-1493 1.62e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1024 LKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKaksltylLTSAKKEIEVMSEELR 1103
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEE-------LEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1104 GLKSEKQLYA--QEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQ----VAEKRYQQEHR 1177
Cdd:COG4717   120 KLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAE 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1178 DRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQvLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENL 1257
Cdd:COG4717   200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA-LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1258 VLVkdkddVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQ 1337
Cdd:COG4717   279 LFL-----VLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1338 EKLsASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQtsnssltKLLEEIKTCRAITDSECIQLLHEKEsl 1417
Cdd:COG4717   354 REA-EELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQ-------ELKEELEELEEQLEELLGELEELLE-- 423

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372 1418 AASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEV--ACQKVAKLKKQQDSLLKEKSALEL 1493
Cdd:COG4717   424 ALDEEELEEELEELEEELEELEEELEELREELAELE----AELEQLEEDGELaeLLQELEELKAELRELAEEWAALKL 497
PRK01156 PRK01156
chromosome segregation protein; Provisional
 743-1319 1.71e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.74  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  743 ELEVLQAKYTEQSEVIGNFTSQLSavkekllDLDALRKANSEGKLELETLRQQLEGAE-------KQIKNLETERNAESS 815
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEIS-------NIDYLEEKLKSSNLELENIKKQIADDEkshsitlKEIERLSIEYNNAMD 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  816 KANSITKELQEkelvLTGLQDSLNQVNQVKETLEKELQTLKEKFAS-----------TSEEAVSAQTRMQDTVNKLHQKE 884
Cdd:PRK01156  233 DYNNLKSALNE----LSSLEDMKNRYESEIKTAESDLSMELEKNNYykeleerhmkiINDPVYKNRNYINDYFKYKNDIE 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  885 EQFNVLS---SELEKLREN---LTDMEA---KFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKER 955
Cdd:PRK01156  309 NKKQILSnidAEINKYHAIikkLSVLQKdynDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIER 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  956 SVEELQLKLTKANENASFLQKSIGEVTLKAEQ-SQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSE 1034
Cdd:PRK01156  389 MSAFISEILKIQEIDPDAIKKELNEINVKLQDiSSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSN 468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1035 TKTKH-EEILQNLQKMLADTEDKLKAAQEANRDLMQdMEELKTQADKAKSLTY--LLTSAKKEIEVMSEELRGLKSEKQL 1111
Cdd:PRK01156  469 HIINHyNEKKSRLEEKIREIEIEVKDIDEKIVDLKK-RKEYLESEEINKSINEynKIESARADLEDIKIKINELKDKHDK 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1112 YaqeaNALKLEKGSLlsKLIEVETKITLLQEDQQKLWSVN-ETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLL 1190
Cdd:PRK01156  548 Y----EEIKNRYKSL--KLEDLDSKRTSWLNALAVISLIDiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSI 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1191 KEInaaQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEhLEGQVKKLTaENLVLVKDKDDVIQKL 1270
Cdd:PRK01156  622 REI---ENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKE-ITSRINDIE-DNLKKSRKALDDAKAN 696

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 568937372 1271 QSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1319
Cdd:PRK01156  697 RARLESTIEILRTRINELSDRINDINETLESMKKIKKAIGDLKRLREAF 745
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
354-812 1.75e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHvlELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:COG4717    81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  434 KRKVEDLQFRVEEESITKGDLEQKspISEDPENTQTKLEHARTK--ELEQSLLFEKTKADKLQRELEDTRVAtvseksri 511
Cdd:COG4717   159 RELEEELEELEAELAELQEELEEL--LEQLSLATEEELQDLAEEleELQQRLAELEEELEEAQEELEELEEE-------- 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  512 MELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALH 591
Cdd:COG4717   229 LEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  592 TATEKLSKENESLRSKLDHANKENSDVIALWKSKLETaIASHQQAMEELKvsfskgigtdsaefaelKTQIERLRLDYQH 671
Cdd:COG4717   309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDR-IEELQELLREAE-----------------ELEEELQLEELEQ 370

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  672 EIESLQSKqdsersAHAKEMETMQAKLMKiiKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKvKELEVLQAKY 751
Cdd:COG4717   371 EIAALLAE------AGVEDEEELRAALEQ--AEEYQELKEELEELEEQLEELLGELEELLEALDEEELE-EELEELEEEL 441

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937372  752 TEQSEVIGNFTSQLSAVKEKLLDLdalrkansEGKLELETLRQQLEGAEKQIKNLETERNA 812
Cdd:COG4717   442 EELEEELEELREELAELEAELEQL--------EEDGELAELLQELEELKAELRELAEEWAA 494
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1165-1458 1.89e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1165 KQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEH 1244
Cdd:pfam07888   54 NRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRE 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1245 LEGQVKKLTAENLvlvkDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLdntCLTLKAERENLLQTNR 1324
Cdd:pfam07888  134 LEEDIKTLTQRVL----ERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSL---SKEFQELRNSLAQRDT 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1325 DLQFEKDTLRQGQEKLSASLEATLQVKQLLsteaETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITD 1404
Cdd:pfam07888  207 QVLQLQDTITTLTQKLTTAHRKEAENEALL----EELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAA 282

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568937372  1405 SECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNE 1458
Cdd:pfam07888  283 QLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQE 336
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
355-498 1.91e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.31  E-value: 1.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  355 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD 420
Cdd:COG2433   347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372  421 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdlEQKSPISEDPEntQTKLEhARTKELEQSLLFEKTKADKLQRELE 498
Cdd:COG2433   427 AEVEELEAELEEKDERIERLERELSEARS-----EERREIRKDRE--ISRLD-REIERLERELEEERERIEELKRKLE 496
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 690-862 2.29e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  690 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNftsqlsaVK 769
Cdd:COG1579    21 RLEHRLKELPAELAELEDELAALEARLEAAKTEL----EDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-------NK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  770 EklldLDALRKansegklELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLE 849
Cdd:COG1579    90 E----YEALQK-------EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAEL 158

                         170
                  ....*....|...
gi 568937372  850 KELQTLKEKFAST 862
Cdd:COG1579   159 EELEAEREELAAK 171
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 375-1122 2.45e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   375 AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVE---AADREKVELLNQLEEEKRKVEDLQFRVEEESITK 451
Cdd:pfam01576   12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETElcaEAEEMRARLAARKQELEEILHELESRLEEEEERS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   452 GDLEQkspisedpentQTKLEHARTKELEQSLLFEKTKADKLQREledtrvaTVSEKSRIMELEKDLALRAQEVAELRRr 531
Cdd:pfam01576   92 QQLQN-----------EKKKMQQHIQDLEEQLDEEEAARQKLQLE-------KVTTEAKIKKLEEDILLLEDQNSKLSK- 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   532 lESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLkehfgarEEAFQKEikalhtatEKLSKENESLRSKLDHA 611
Cdd:pfam01576  153 -ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDL-------EERLKKE--------EKGRQELEKAKRKLEGE 216

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   612 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKgigtdSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEM 691
Cdd:pfam01576  217 STDLQEQIAELQAQIAELRAQLAKKEEELQAALAR-----LEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAE 291

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   692 ET---MQAKLMKIIKEKEDSLE--AVKARLDSAEDQHLVEMEDTLnklqEAEIKVKELEVLQAKyTEQSEVIGNFTSQLS 766
Cdd:pfam01576  292 KQrrdLGEELEALKTELEDTLDttAAQQELRSKREQEVTELKKAL----EEETRSHEAQLQEMR-QKHTQALEELTEQLE 366

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   767 AVKEKLLDLD----ALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN 842
Cdd:pfam01576  367 QAKRNKANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVS 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   843 QVKETLEKELQTLkekfastSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAK 922
Cdd:pfam01576  447 SLLNEAEGKNIKL-------SKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQL 519

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   923 EKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQS--QQQAARKHEEEK 1000
Cdd:pfam01576  520 STLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvDLDHQRQLVSNL 599

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1001 KELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLadteDKLKAAQEANRDLMQDMEELKTQADK 1080
Cdd:pfam01576  600 EKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEAL----EAKEELERTNKQLRAEMEDLVSSKDD 675

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 568937372  1081 AKSLTYLLTSAKKEIEVMSEELRGL--KSEKQLYAQEANALKLE 1122
Cdd:pfam01576  676 VGKNVHELERSKRALEQQVEEMKTQleELEDELQATEDAKLRLE 719
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1229-1979 2.55e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1229 DKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALV------QEIEDLTTEKKSAAEKQ 1302
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLRealqqtQQSHAYLTQKREAQEEQ 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1303 MSLDNTCLTLKAERENL--LQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMR 1380
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELraQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1381 Q---LQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASE--RTLLAEKEELLSENRIITEKLSKQSEEVArlemg 1455
Cdd:TIGR00618  336 QqssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQSLCKELDILQREQA----- 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1456 lneKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYD----QEATNRRIVMQEKM 1531
Cdd:TIGR00618  411 ---TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKereqQLQTKEQIHLQETR 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1532 KllgnidalKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEhTSMIQAKDNLNAELKTcccEKNMLLRDGLNLQ 1611
Cdd:TIGR00618  488 K--------KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL-TRRMQRGEQTYAQLET---SEEDVYHQLTSER 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1612 EECQKLNEEIREIQQTLILEKEARAKESEtslyENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLtQEKTNSEQKVEEI 1691
Cdd:TIGR00618  556 KQRASLKEQMQEIQQSFSILTQCDNRSKE----DIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL-LRKLQPEQDLQDV 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1692 IKEKELLSAETAQLAANIETLKSDFAAlsksklELQELHSCLTKILDDLRLNHEVALTERaevLQDNKNLLAEKREMMLR 1771
Cdd:TIGR00618  631 RLHLQQCSQELALKLTALHALQLTLTQ------ERVREHALSIRVLPKELLASRQLALQK---MQSEKEQLTYWKEMLAQ 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1772 NEEALKEKEKLEESYFILQKEISQLaqtnshisanlleSQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME 1851
Cdd:TIGR00618  702 CQTLLRELETHIEEYDREFNEIENA-------------SSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1852 QMTKEkTETLASLEDTKQTNARLQNELDTLkennlktveeLNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQ 1931
Cdd:TIGR00618  769 EVTAA-LQTGAELSHLAAEIQFFNRLREED----------THLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL 837

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 568937372  1932 EENvklaeelGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDA 1979
Cdd:TIGR00618  838 EEK-------SATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 684-929 2.71e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 42.71  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   684 RSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTS 763
Cdd:pfam05667  231 LASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGLTKGSRFTHTEKLQFTN 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   764 QLSAVKEKLL----DLDALRKANSEgklELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLN 839
Cdd:pfam05667  311 EAPAATSSPPtkveTEEELQQQREE---ELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   840 ------------QVNQVKetLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ----KEEQFNVLSSELEKLRENLTD 903
Cdd:pfam05667  388 vkkktldllpdaEENIAK--LQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEaksnKEDESQRKLEEIKELREKIKE 465

                          250       260
                   ....*....|....*....|....*.
gi 568937372   904 MEAKFKEKDDREDQLVKAKEKLENDI 929
Cdd:pfam05667  466 VAEEAKQKEELYKQLVAEYERLPKDV 491
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1534-1971 2.74e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1534 LGNIDALKKELQERKKENQELTSSKCDLSLL---LKEAQDAKKNLEKEHTSMIQAKDN---------LNAELKTCCCEKN 1601
Cdd:COG4717    70 LKELKELEEELKEAEEKEEEYAELQEELEELeeeLEELEAELEELREELEKLEKLLQLlplyqeleaLEAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1602 ML---LRDGLNLQEECQKLNEEIREIQQTLILEKE----ARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTEn 1674
Cdd:COG4717   150 ELeerLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE- 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1675 FTLTQEKTNSEQKVEEIIKEKELLSAETAQLAanIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEV 1754
Cdd:COG4717   229 LEQLENELEAAALEERLKEARLLLLIAAALLA--LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1755 LQdnknllAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHIsanllesQSENRTLRKDKSKLTLKIRELETL 1834
Cdd:COG4717   307 LQ------ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL-------QELLREAEELEEELQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1835 HSFTAAQTAEDamqimeqmtkektETLASLEDTKQTNARLQNELDTLKENnlktVEELNKSKELLSVENQKmEEFKKEIE 1914
Cdd:COG4717   374 ALLAEAGVEDE-------------EELRAALEQAEEYQELKEELEELEEQ----LEELLGELEELLEALDE-EELEEELE 435

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568937372 1915 TLKQAAAQKSQQLSALQEENVKLAEELGRTRDEvTSHQKLEEERSVLNNQLLEMKKR 1971
Cdd:COG4717   436 ELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAELRELAEE 491
mukB PRK04863
chromosome partition protein MukB;
863-1254 2.80e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  863 SEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREdQLVKAKEKLENDIAeimKMSGDnssq 942
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIE---RYQAD---- 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  943 LTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAEQSQQQAArkheeekkeleekllelEKKMETSYNQCQ 1022
Cdd:PRK04863  357 LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDE--LKSQLADYQQA-----------------LDVQQTRAIQYQ 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1023 DLKAKYEKASSETKTKHEEiLQNLQKMLADTEDKLKAAQEANRDLMQDM---EELKTQADKAKSltyLLTSAKKEIE--- 1096
Cdd:PRK04863  418 QAVQALERAKQLCGLPDLT-ADNAEDWLEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQ---LVRKIAGEVSrse 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1097 ---VMSEELRGLKSEKQLyAQEANALKLEKGSLLSKLIEVETKITLLQEDQQK----------LWSVNETLHLEKERVSE 1163
Cdd:PRK04863  494 awdVARELLRRLREQRHL-AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRlgknlddedeLEQLQEELEARLESLSE 572

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1164 EKQVAEKRYQQEHRDRESLVAEREKLLK---EINAAQEEL--LKMHMENDSLEASKVS--MQVLIEELRfckdKLMAMSE 1236
Cdd:PRK04863  573 SVSEARERRMALRQQLEQLQARIQRLAArapAWLAAQDALarLREQSGEEFEDSQDVTeyMQQLLERER----ELTVERD 648

                         410
                  ....*....|....*...
gi 568937372 1237 KARAEKEHLEGQVKKLTA 1254
Cdd:PRK04863  649 ELAARKQALDEEIERLSQ 666
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1409-2131 2.89e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1409 QLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEvacqKVAKLKKQQDSLLKEK 1488
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDN----EIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1489 SALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKmkllgnIDALKKELQERKKENQELTSSKCDLSLLLK-- 1566
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRE------LEKLNKERRLLNQEKTELLVEQGRLQLQADrh 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1567 EAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYEN 1646
Cdd:TIGR00606  360 QEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLG 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1647 NKLHGRVVLLEEEIQRLRVCSEQLQTenftLTQEKTNSEQKVEEIIKEKELLSaeTAQLAANIETLKSDFAALSKSKLEL 1726
Cdd:TIGR00606  440 RTIELKKEILEKKQEELKFVIKELQQ----LEGSSDRILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADL 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1727 QELHSCLTKILDDLRlNHEVALTERAEVLQDNKNLLAEKREMMLRNEEAL---------------------KEKEKLEES 1785
Cdd:TIGR00606  514 DRKLRKLDQEMEQLN-HHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELtsllgyfpnkkqledwlhsksKEINQTRDR 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1786 YFILQKEISQLAQTNSHISaNLLESQSENRTLRKDK-----------SKLTLKIRELETLHSFTAAQTAEDAM--QIMEQ 1852
Cdd:TIGR00606  593 LAKLNKELASLEQNKNHIN-NELESKEEQLSSYEDKlfdvcgsqdeeSDLERLKEEIEKSSKQRAMLAGATAVysQFITQ 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1853 MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQE 1932
Cdd:TIGR00606  672 LTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1933 ENVKLAEELGRTRDEVTSHQKLEE--------------ERSVLNNQLLEMKKRESEFRKDADEEKAS-LQKSISLTSALL 1997
Cdd:TIGR00606  752 KLQKVNRDIQRLKNDIEEQETLLGtimpeeesakvcltDVTIMERFQMELKDVERKIAQQAAKLQGSdLDRTVQQVNQEK 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1998 TEKDAELEKLRNEVTVLRG----ENATAKSLHSVVQTLESDKVKLELKVKNLElQLKENKRQLSS--SSGNTDAQAEEDE 2071
Cdd:TIGR00606  832 QEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ-QFEEQLVELSTevQSLIREIKDAKEQ 910

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372  2072 RAQESQQMIDFLNSVIVDLQRKNQDLK---MKVEMMSEAALN--GNGEDLNSYDSDDQEKQSKKK 2131
Cdd:TIGR00606  911 DSPLETFLEKDQQEKEELISSKETSNKkaqDKVNDIKEKVKNihGYMKDIENKIQDGKDDYLKQK 975
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 786-955 3.26e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 3.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  786 KLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKelvltgLQDSLNQvnqvketLEKELQTLKEKFastsEE 865
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAE------LRDELAE-------LEEELEALKARW----EA 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  866 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDredqlvkakeklENDIAEIM---------KMS 936
Cdd:COG0542   466 EKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVT------------EEDIAEVVsrwtgipvgKLL 533

                         170
                  ....*....|....*....
gi 568937372  937 GDNSSQLTKMNDElrLKER 955
Cdd:COG0542   534 EGEREKLLNLEEE--LHER 550
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1509-2017 3.27e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1509 IGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDN 1588
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1589 LNAELKTCcceknmllRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYE----NNKLHGRVVLLEEEIQRLR 1664
Cdd:pfam01576  157 LEERISEF--------TSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQElekaKRKLEGESTDLQEQIAELQ 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1665 VCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAA--LSKSKLELQ------ELHSCLTKI 1736
Cdd:pfam01576  229 AQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESerAARNKAEKQrrdlgeELEALKTEL 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1737 LD---------DLRLNHEVALTERAEVLQDN-KNLLAEKREMMLRNEEALKE-KEKLEESY---FILQKEISQLAQTNSH 1802
Cdd:pfam01576  309 EDtldttaaqqELRSKREQEVTELKKALEEEtRSHEAQLQEMRQKHTQALEElTEQLEQAKrnkANLEKAKQALESENAE 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1803 ISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEdAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLK 1882
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAE-LAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLE 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1883 EnnlktveELNKSKELLSVENQkmeefkkeietlkqAAAQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLN 1962
Cdd:pfam01576  468 S-------QLQDTQELLQEETR--------------QKLNLSTRLRQLEDERNSLQEQL---EEEEEAKRNVERQLSTLQ 523

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372  1963 NQLLEMKKRESEFR---KDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 2017
Cdd:pfam01576  524 AQLSDMKKKLEEDAgtlEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE 581
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1130-2077 3.32e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1130 LIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDS 1209
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1210 LEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQsayeelvKDQKALVQEIE 1289
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLL----EDQNSKLS-------KERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1290 DLTTEKKSAAEKQMSLDNtcltlkaerenllqtnrdlqfekdtLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCAS 1369
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSK-------------------------LKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGES 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1370 KALRKAELDMR-QLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSEnRIITEKLSKQ--- 1445
Cdd:pfam01576  218 TDLQEQIAELQaQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQrrd 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1446 -SEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLladRESSIKTIGDLRRKYDQEATNRR 1524
Cdd:pfam01576  297 lGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEM---RQKHTQALEELTEQLEQAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1525 IVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLL 1604
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAE 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1605 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTenftLTQEKTNS 1684
Cdd:pfam01576  454 GKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLST----LQAQLSDM 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1685 EQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDL--RLNHEVALTERAEVLQDN-KNL 1761
Cdd:pfam01576  530 KKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvDLDHQRQLVSNLEKKQKKfDQM 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1762 LAEKREMMLRN-------------------------EEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRT 1816
Cdd:pfam01576  610 LAEEKAISARYaeerdraeaeareketralslaralEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1817 LRKDKSKLTLKIRELETlhSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQ-----NELDTLKENNLKTVEE 1891
Cdd:pfam01576  690 LEQQVEEMKTQLEELED--ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQlvkqvRELEAELEDERKQRAQ 767

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1892 LNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNN----QLLE 1967
Cdd:pfam01576  768 AVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEaellQLQE 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1968 MKKRESEFRKDADEEKASLQKSI----SLTSALLTEK-------------------DAELEKLRNEVTVLRGENATAK-- 2022
Cdd:pfam01576  848 DLAASERARRQAQQERDELADEIasgaSGKSALQDEKrrleariaqleeeleeeqsNTELLNDRLRKSTLQVEQLTTEla 927

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568937372  2023 SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQ 2077
Cdd:pfam01576  928 AERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQ 982
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1472-1721 3.45e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1472 QKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKEn 1551
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1552 qeltsskcdLSLLLKEAQdakKNLEKEHTSMIQAKDNLNAelktccceknmLLRDGLNLQEECQKLNEEIREIQQTLile 1631
Cdd:COG4942   106 ---------LAELLRALY---RLGRQPPLALLLSPEDFLD-----------AVRRLQYLKYLAPARREQAEELRADL--- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1632 kearakesetslyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIET 1711
Cdd:COG4942   160 ---------------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224

                         250
                  ....*....|
gi 568937372 1712 LKSDFAALSK 1721
Cdd:COG4942   225 LEALIARLEA 234
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1170-1626 3.57e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1170 KRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSE--KARAEKEHLEG 1247
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1248 QVKKLtaenlvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSldntclTLKAERENLLQTNRDLQ 1327
Cdd:COG4717   147 RLEEL--------EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ------DLAEELEELQQRLAELE 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1328 FEKDTLRQGQEKLSASLEAtLQVKQLLSTEAETLRTQldcasKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSEC 1407
Cdd:COG4717   213 EELEEAQEELEELEEELEQ-LENELEAAALEERLKEA-----RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1408 IQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKE 1487
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1488 KSALELQNgdLLAdrESSIKTIGDLRRKYDQEatnrrivmQEKMKLLGNIDALKKELQERKKENQEL--TSSKCDLSLLL 1565
Cdd:COG4717   367 ELEQEIAA--LLA--EAGVEDEEELRAALEQA--------EEYQELKEELEELEEQLEELLGELEELleALDEEELEEEL 434

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937372 1566 KEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmLLRDGL--NLQEECQKLNEEIREIQQ 1626
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQ-------LEEDGElaELLQELEELKAELRELAE 490
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 435-1582 3.58e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 3.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   435 RKVEDLQFRVEEESITKGDLEQKSPISEDPENTQTKLEHartkelEQSLLFEKTKAD-KLQRELEDTRVATVSEKSRIME 513
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCE------EKNALQEQLQAEtELCAEAEEMRARLAARKQELEE 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   514 LEKDLALRAQEVAELRRRLESSKPpgdvdmslSLLQEISALQEKLEAIHTDHQgEMTSLKEHFGAREEAFQKEIKALHTA 593
Cdd:pfam01576   76 ILHELESRLEEEEERSQQLQNEKK--------KMQQHIQDLEEQLDEEEAARQ-KLQLEKVTTEAKIKKLEEDILLLEDQ 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   594 TEKLSKENESLRSKL----DHANKENSDVIALWKSKLEtaiasHQQAMEELKVSFSKGIGTdSAEFAELKTQIERLRLDY 669
Cdd:pfam01576  147 NSKLSKERKLLEERIseftSNLAEEEEKAKSLSKLKNK-----HEAMISDLEERLKKEEKG-RQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   670 QHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKArldsaedqhLVEMEDTLNKLQEaeikvkELEVLQA 749
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKK---------IRELEAQISELQE------DLESERA 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   750 KYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGA-EKQIKNLETERNAESSKANSITKELQEKe 828
Cdd:pfam01576  286 ARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQ- 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   829 lvltglqdsLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfnvlsseLEKLRENLTDMEakf 908
Cdd:pfam01576  365 ---------LEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQ-------LQELQARLSESE--- 425

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   909 KEKDDREDQLVKAKEKLENdIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGE--VTLKAE 986
Cdd:pfam01576  426 RQRAELAEKLSKLQSELES-VSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDerNSLQEQ 504

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   987 QSQQQAARKheeekkeleekllELEKKMETSYNQCQDLKAKYEKASS------ETKTKHEEILQNLQKMLADTEDKLKAA 1060
Cdd:pfam01576  505 LEEEEEAKR-------------NVERQLSTLQAQLSDMKKKLEEDAGtlealeEGKKRLQRELEALTQQLEEKAAAYDKL 571

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1061 QEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGL---------KSEKQLYAQEANALKLEKG--SLLSK 1129
Cdd:pfam01576  572 EKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAIsaryaeerdRAEAEAREKETRALSLARAleEALEA 651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1130 LIEVETKITLLQEDQQKLWS----VNETLH-LEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEIN----AAQEEl 1200
Cdd:pfam01576  652 KEELERTNKQLRAEMEDLVSskddVGKNVHeLERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNmqalKAQFE- 730

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1201 LKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQ---KLQSAYEEL 1277
Cdd:pfam01576  731 RDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKqlkKLQAQMKDL 810

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1278 VKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLrqgQEKLSASLEAtlqvKQLLSTE 1357
Cdd:pfam01576  811 QRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDEL---ADEIASGASG----KSALQDE 883

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1358 AETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRi 1437
Cdd:pfam01576  884 KRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVK- 962

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1438 iteklSKQSEEVARLEmglnekityltsekevacQKVAKLKKQQDSLLKEKSAlelqNGDLLADRESSIKtigDLRRKYD 1517
Cdd:pfam01576  963 -----SKFKSSIAALE------------------AKIAQLEEQLEQESRERQA----ANKLVRRTEKKLK---EVLLQVE 1012

                         1130      1140      1150      1160      1170      1180
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372  1518 QEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM 1582
Cdd:pfam01576 1013 DERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTL 1077
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 351-534 3.77e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARdghdQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  431 EEEKRKVEDL---QFRVEEESITKGDLEQKSP------------ISEDPENTQTKLEHART--KELEQSLLFEKTKADKL 493
Cdd:COG4942   100 EAQKEELAELlraLYRLGRQPPLALLLSPEDFldavrrlqylkyLAPARREQAEELRADLAelAALRAELEAERAELEAL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 568937372  494 QRELEDTRVATVSEKSR----IMELEKDLALRAQEVAELRRRLES 534
Cdd:COG4942   180 LAELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEE 224
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1656-1843 3.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1656 LEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTK 1735
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1736 ILDDLRLNHEVAL------------------------TERAEVLQDNKNLLAEKREMMLRNEEALKE-KEKLEESYFILQ 1790
Cdd:COG4942   112 ALYRLGRQPPLALllspedfldavrrlqylkylaparREQAEELRADLAELAALRAELEAERAELEAlLAELEEERAALE 191

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568937372 1791 KEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1843
Cdd:COG4942   192 ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 410-1042 4.05e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 4.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   410 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSPISEDpentQTKLEHARTKELEQSLLFEKTK 489
Cdd:TIGR00606  419 SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR----ILELDQELRKAERELSKAEKNS 494

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   490 AdklqreLEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdMSLSLLQEISALQEKLEAIHTDHQGEM 569
Cdd:TIGR00606  495 L------TETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT------QMEMLTKDKMDKDEQIRKIKSRHSDEL 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   570 TSLKEHFGAREE------AFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIA---------------------LW 622
Cdd:TIGR00606  563 TSLLGYFPNKKQledwlhSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEqlssyedklfdvcgsqdeesdLE 642

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   623 KSKLETAIASHQQAMEELKVSFSKGIGTDS------------------AEFAELKTQIE---RLRLDYQHEIESLQSKQD 681
Cdd:TIGR00606  643 RLKEEIEKSSKQRAMLAGATAVYSQFITQLtdenqsccpvcqrvfqteAELQEFISDLQsklRLAPDKLKSTESELKKKE 722

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   682 SERSAHAKEMETMQAKLMKIIKE------KEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQS 755
Cdd:TIGR00606  723 KRRDEMLGLAPGRQSIIDLKEKEipelrnKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELK 802

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   756 EVIGNFTSQLSAVKEKLLDL--DALRKANSEGKLELETLRQQLE-------GAEKQIKNLETERNAESSKANSITKELQ- 825
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSDLDRtvQQVNQEKQEKQHELDTVVSKIElnrkliqDQQEQIQHLKSKTNELKSEKLQIGTNLQr 882

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   826 -------------EKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSS 892
Cdd:TIGR00606  883 rqqfeeqlvelstEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIEN 962

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   893 ELEKLREN-LTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENA 971
Cdd:TIGR00606  963 KIQDGKDDyLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLK 1042

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372   972 SFLQKSIGEVTL---KAEQSQQQAARKHEEEKKELEE-KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEI 1042
Cdd:TIGR00606 1043 EMGQMQVLQMKQehqKLEENIDLIKRNHVLALGRQKGyEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTELVN 1117
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1883-2131 4.18e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.25  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1883 ENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAA----AQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEER 1958
Cdd:COG5185   232 EEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKlgenAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKAT 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1959 SVLNNQLLEMKKrESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKS---LHSVVQTLESDK 2035
Cdd:COG5185   312 ESLEEQLAAAEA-EQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSseeLDSFKDTIESTK 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2036 VKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQqmidfLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGED 2115
Cdd:COG5185   391 ESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQA-----TSSNEEVSKLLNELISELNKVMREADEESQSRL 465

                         250
                  ....*....|....*.
gi 568937372 2116 LNSYDSDDQEKQSKKK 2131
Cdd:COG5185   466 EEAYDEINRSVRSKKE 481
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 913-1122 4.44e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  913 DREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLK-AEQSQQQ 991
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEiAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  992 AARKHEEEKKELEEKLLELEKKMETSYNQCQDLKA----KYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDL 1067
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372 1068 MQDMEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1122
Cdd:COG4942   180 LAELEEERAALEALKAeRQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 461-688 4.44e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  461 SEDPENTQTKLE--HARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPP 538
Cdd:COG4942    19 ADAAAEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  539 -----GDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANK 613
Cdd:COG4942    99 leaqkEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937372  614 ENSDVIALwKSKLETAIASHQQAMEELKVSFSKgigtDSAEFAELKTQIERLrldyQHEIESLQSKQDSERSAHA 688
Cdd:COG4942   179 LLAELEEE-RAALEALKAERQKLLARLEKELAE----LAAELAELQQEAEEL----EALIARLEAEAAAAAERTP 244
46 PHA02562
endonuclease subunit; Provisional
 672-937 4.52e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 4.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  672 EIESLQSKQDsersaHAKEMETMQAKLMKIIKEKEDsleAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKY 751
Cdd:PHA02562  182 QIQTLDMKID-----HIQQQIKTYNKNIEEQRKKNG---ENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  752 TEQSEVIGNFTSQLSAvkeKLLDLDALRKANSEGKlELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkelvL 831
Cdd:PHA02562  254 SAALNKLNTAAAKIKS---KIEQFQKVIKMYEKGG-VCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDE----L 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  832 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQdtvnklhQKEEQFNVLSSELEKLRENLTDmeaKFKEK 911
Cdd:PHA02562  326 EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQDELDK---IVKTK 395

                         250       260
                  ....*....|....*....|....*..
gi 568937372  912 DDredqlvKAKEKLENDIA-EIMKMSG 937
Cdd:PHA02562  396 SE------LVKEKYHRGIVtDLLKDSG 416
PTZ00121 PTZ00121
MAEBL; Provisional
 1743-2131 4.84e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 4.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1743 NHEVALTERAEVLQDNKNLLAEKRemmlrNEEALKEKEKLEESYFILQKEISQLAQTNSHISANllESQSENRTLRKDKS 1822
Cdd:PTZ00121 1055 NHEGKAEAKAHVGQDEGLKPSYKD-----FDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEE--ARKAEEAKKKAEDA 1127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1823 KLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKE---KTETLASLEDTKQTNA-----RLQNELDTLKENNLKTVEELNK 1894
Cdd:PTZ00121 1128 RKAEEARKAEDARKAEEARKAEDAKRVEIARKAEdarKAEEARKAEDAKKAEAarkaeEVRKAEELRKAEDARKAEAARK 1207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1895 SKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSH-------QKLEEERSVLNNQLLE 1967
Cdd:PTZ00121 1208 AEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHfarrqaaIKAEEARKADELKKAE 1287

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1968 MKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLEL 2047
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 2048 QLKENKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQ 2127
Cdd:PTZ00121 1368 AAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAD 1447


                  ....
gi 568937372 2128 SKKK 2131
Cdd:PTZ00121 1448 EAKK 1451
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 788-995 5.02e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 5.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  788 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLN----QVNQVKETLEKELQTLKEKFASTS 863
Cdd:COG3883    24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaeaEIEERREELGERARALYRSGGSVS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  864 E-EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQ 942
Cdd:COG3883   104 YlDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568937372  943 LTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARK 995
Cdd:COG3883   184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 670-911 5.10e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 5.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  670 QHEIESLQSKQDSERSAhAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKLQeaeikvKELEVLQA 749
Cdd:COG4942    26 EAELEQLQQEIAELEKE-LAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEAELAELE------KEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  750 KYTEQSEVIGNFtsqlsavkeklldLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkel 829
Cdd:COG4942    98 ELEAQKEELAEL-------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE--- 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  830 vLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 909
Cdd:COG4942   162 -LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 568937372  910 EK 911
Cdd:COG4942   241 ER 242
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
658-843 5.11e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 5.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  658 LKTQIERLR---LDYQHEIESLQSKQ-----DSERSAHAKEMETMQAKLMKI---IKEKEDSLEAVKARLDSAEDQHLVE 726
Cdd:COG3206   180 LEEQLPELRkelEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEAraeLAEAEARLAALRAQLGSGPDALPEL 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  727 MEDT-----LNKLQEAEIkvkELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLD-----LDALRKANSEGKLELETLRQQL 796
Cdd:COG3206   260 LQSPviqqlRAQLAELEA---ELAELSARYTPNHPDVIALRAQIAALRAQLQQeaqriLASLEAELEALQAREASLQAQL 336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 568937372  797 EGAEKQIKNLeterNAESSKANSITKELQEKELVLTGLQDSLNQVNQ 843
Cdd:COG3206   337 AQLEARLAEL----PELEAELRRLEREVEVARELYESLLQRLEEARL 379
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
400-995 5.35e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 5.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  400 QHVLELEAKMDQLRTMVEAADrEKVELLNQLEEEKRKVEDLQfrveeesitkgdleqksPISEDPENTQTKLEHARTKEL 479
Cdd:COG4913   215 EYMLEEPDTFEAADALVEHFD-DLERAHEALEDAREQIELLE-----------------PIRELAERYAAARERLAELEY 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  480 EQSLL---FEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSkppgDVDMSLSLLQEISALQE 556
Cdd:COG4913   277 LRAALrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGN----GGDRLEQLEREIERLER 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  557 KLEAIhtdhqgemtslkehfGAREEAFQKEIKALHTATEKLSKENESLRSKLDHAnkensdvialwKSKLETAIASHQQA 636
Cdd:COG4913   353 ELEER---------------ERRRARLEALLAALGLPLPASAEEFAALRAEAAAL-----------LEALEEELEALEEA 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  637 MEELKvsfskgigtdsAEFAELKTQIERLrldyQHEIESLQSKqdseRSAHAKEMETMQAKLMKIIKEKEDSL----EAV 712
Cdd:COG4913   407 LAEAE-----------AALRDLRRELREL----EAEIASLERR----KSNIPARLLALRDALAEALGLDEAELpfvgELI 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  713 KARLDSA-------------------EDQHL------VEMEDTLNKLQEAEIKVKELEVLQAKYTEQS---EVIGNFTSQ 764
Cdd:COG4913   468 EVRPEEErwrgaiervlggfaltllvPPEHYaaalrwVNRLHLRGRLVYERVRTGLPDPERPRLDPDSlagKLDFKPHPF 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  765 LSAVKEKLLDLDALRKANSEGKLELETLRQQLEG--------------------------AEKQIKNLETERNAesskan 818
Cdd:COG4913   548 RAWLEAELGRRFDYVCVDSPEELRRHPRAITRAGqvkgngtrhekddrrrirsryvlgfdNRAKLAALEAELAE------ 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  819 sitkelqekelvltgLQDSLNQVNQVKETLEKELQTLKEKFA--STSEEAVSAQTRMQDTVNKLHQKEEQFNVL---SSE 893
Cdd:COG4913   622 ---------------LEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLdasSDD 686

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  894 LEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASF 973
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766

                         650       660
                  ....*....|....*....|..
gi 568937372  974 LQKSIGEVTLKAEQSQQQAARK 995
Cdd:COG4913   767 LRENLEERIDALRARLNRAEEE 788
mukB PRK04863
chromosome partition protein MukB;
578-979 5.49e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 5.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  578 ARE---EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALW-KSKLETAIASHQQAMEELkvsfskgigtdSA 653
Cdd:PRK04863  783 AREkriEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfEADPEAELRQLNRRRVEL-----------ER 851

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  654 EFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAvkARLDSAEDQHLVEMEDTLNK 733
Cdd:PRK04863  852 ALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEA--KRFVQQHGNALAQLEPIVSV 929

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  734 LQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLE-----LETLRQQLEGAEKQIKNLET 808
Cdd:PRK04863  930 LQSDP---EQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAknsdlNEKLRQRLEQAEQERTRARE 1006

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  809 E-RNAESskansitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQtrmQDTVNK-LHQKEEQ 886
Cdd:PRK04863 1007 QlRQAQA--------QLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR---RDELHArLSANRSR 1075

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  887 FNVLSSELEKLRENLTDMEAKFK--EKD--DREDQLVKAKekleNDIAEIMKMSGDNSsqltkmnDELRLKERSVEELql 962
Cdd:PRK04863 1076 RNQLEKQLTFCEAEMDNLTKKLRklERDyhEMREQVVNAK----AGWCAVLRLVKDNG-------VERRLHRRELAYL-- 1142

                         410
                  ....*....|....*..
gi 568937372  963 kltKANENASFLQKSIG 979
Cdd:PRK04863 1143 ---SADELRSMSDKALG 1156
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1224-1753 5.95e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1224 LRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQM 1303
Cdd:COG4717    40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1304 SLdntcltlkaerENLLQTNRDLQfekdtlrqgqeklsasleatlqvkqllstEAETLRTQLDCASKALRKAELDMRQLQ 1383
Cdd:COG4717   120 KL-----------EKLLQLLPLYQ-----------------------------ELEALEAELAELPERLEELEERLEELR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1384 TSNSSLTKLLEEIKTCRAITDSECIQLLHEKEslaASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYL 1463
Cdd:COG4717   160 ELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELE----EELEQL 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1464 TSEKEVAcQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGDL-------------RRKYDQEATNRRIVMQE 1529
Cdd:COG4717   233 ENELEAA-ALEERLKEARLLLLIAAALLALLgLGGSLLSLILTIAGVLFLvlgllallflllaREKASLGKEAEELQALP 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1530 KMKLLGNIDaLKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM--IQAKDNLNAELKTCCCEKNMLLRDG 1607
Cdd:COG4717   312 ALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAA 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1608 LNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENnklhgrvvlLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQK 1687
Cdd:COG4717   391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE---------LEEELEELEEELEELEEELEELREELAELEAE 461

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372 1688 VEEIIKEKELlsaetAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAE 1753
Cdd:COG4717   462 LEQLEEDGEL-----AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 581-871 6.07e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.48  E-value: 6.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  581 EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAE----FA 656
Cdd:COG5185   242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  657 ELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEdsLEAVKARLDSAEDQHLVEMEDTLNKLQE 736
Cdd:COG5185   322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  737 AEIKVKE-LEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESS 815
Cdd:COG5185   400 QRGYAQEiLATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSK 479

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937372  816 KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQT 871
Cdd:COG5185   480 KEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGY 535
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1020-1206 7.44e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 7.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1020 QCQDLKAKYEKASSETKT--KHEEILQNLQKmLADTEDKLKAAQEANRDLMQDMEElktqadkaksltylLTSAKKEIEV 1097
Cdd:COG4913   625 ELAEAEERLEALEAELDAlqERREALQRLAE-YSWDEIDVASAEREIAELEAELER--------------LDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1098 MSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQklwsvnetlHLEKERVSEEKQVAEKRYQQEHR 1177
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE---------AAEDLARLELRALLEERFAAALG 760

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568937372 1178 D------RESLVAEREKLLKEINAAQEELLKMHME 1206
Cdd:COG4913   761 DaverelRENLEERIDALRARLNRAEEELERAMRA 795
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 552-1391 8.36e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.57  E-value: 8.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   552 SALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENS------DVIALWKSK 625
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGrlqlqaDRHQEHIRA 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   626 LETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQ--------IERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAK 697
Cdd:TIGR00606  366 RDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIErqedeaktAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELK 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   698 LMKIIKEKEDsLEAVKARLDSAE---------DQHLVEMEDTLNKLQE---AEIKVKELEVLQA--------------KY 751
Cdd:TIGR00606  446 KEILEKKQEE-LKFVIKELQQLEgssdrilelDQELRKAERELSKAEKnslTETLKKEVKSLQNekadldrklrkldqEM 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   752 TEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETlrqqLEGAEKQIKNLETERNAESSKANSITKELQEKELVL 831
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTS----LLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   832 TGLQDSLNQVNQVKETLEKELQTLKEKF--ASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 909
Cdd:TIGR00606  601 ASLEQNKNHINNELESKEEQLSSYEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCC 680

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   910 EKDDREdqlVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQ 989
Cdd:TIGR00606  681 PVCQRV---FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVN 757

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372   990 QQAARKHEEEKKELEEKLLELEKkmETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMlaDTEDKLKAAQEANRDLMQ 1069
Cdd:TIGR00606  758 RDIQRLKNDIEEQETLLGTIMPE--EESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL--QGSDLDRTVQQVNQEKQE 833

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1070 DMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEK-QLYAQEANALKLEKgsllskliEVETKITLLQEdqqklw 1148
Cdd:TIGR00606  834 KQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKlQIGTNLQRRQQFEE--------QLVELSTEVQS------ 899

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1149 sVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEAskvsmQVLIEELRFCK 1228
Cdd:TIGR00606  900 -LIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIEN-----KIQDGKDDYLK 973

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1229 DKLMAMSeKARAEKEHLEGQVKKLTAENLVLVKDKDDviqklQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNT 1308
Cdd:TIGR00606  974 QKETELN-TVNAQLEECEKHQEKINEDMRLMRQDIDT-----QKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQM 1047

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  1309 CLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSAsleatlqvKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSS 1388
Cdd:TIGR00606 1048 QVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYE--------KEIKHFKKELREPQFRDAEEKYREMMIVMRTTELVNKD 1119


                   ...
gi 568937372  1389 LTK 1391
Cdd:TIGR00606 1120 LDI 1122
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1321-1550 8.56e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1321 QTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRK-------AELDMRQLQTSNSSLTKLL 1393
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAleqelaaLEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372 1394 EEIKTCRAitdseciqllhekESLAASERTLLAEKEELLSENRIITEkLSKQSEEVARLEMGLNEKITYLTSEKEVACQK 1473
Cdd:COG4942   100 EAQKEELA-------------ELLRALYRLGRQPPLALLLSPEDFLD-AVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937372 1474 VAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKE 1550
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 623-840 9.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 9.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  623 KSKLETAIASHQQAMEELKvsfsKGIGTDSAEFAELKTQIERLrldyqheiESLQSKQDSERSAHAKEMETMQAKLMKII 702
Cdd:COG4942    29 LEQLQQEIAELEKELAALK----KEEKALLKQLAALERRIAAL--------ARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937372  703 KEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN 782
Cdd:COG4942    97 AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937372  783 SEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQ 840
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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