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Conserved domains on  [gi|568908635|ref|XP_006529440|]
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neuron navigator 1 isoform X8 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 27-277 1.67e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 1.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   27 ASRPHYASSIPVPRASSQTRIHTPGASPQLRPRQQAdlalSPQRGASPRRG--KAAVSSRNSSPKAYRGRGTPRAAGPAR 104
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP----APGRVSRPRRArrLGRAAQASSPPQRPRRRAARPTVGSLT 2696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  105 ELA-----GSVESLPSSPWNSPRVTPKTALSSQAGSRRAGETQSTQRKKTQEGIPVRHTRGRSPPQSScygetqipGPPE 179
Cdd:PHA03247 2697 SLAdppppPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTA--------GPPA 2768

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  180 GRMPpgcqgkdqRNIISKPPRCLEPDEGeASGTSSPVCSPVQSMRSSATPGVISFSSAHPQSQPITATVAPFQYRLQTDQ 259
Cdd:PHA03247 2769 PAPP--------AAPAAGPPRRLTRPAV-ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP 2839

                         250
                  ....*....|....*....
gi 568908635  260 EPGPVP-QESWVLDGYTSP 277
Cdd:PHA03247 2840 PPPPGPpPPSLPLGGSVAP 2858
IS21_help_AAA super family cl41901
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 1742-1895 3.49e-05

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


The actual alignment was detected with superfamily member NF038214:

Pssm-ID: 439516  Cd Length: 232  Bit Score: 47.47  E-value: 3.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1742 RRGVNNISVALK--GLK-EKCVDSLVFETL--IPKPMMQHYISL--LLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGR 1814
Cdd:NF038214   41 ERENRRIERRLKraRFPaAKTLEDFDFTAApgLDKAQIRELATLdfIERAENVLLLGPPGTGKTHLAIALGYAACRQGYR 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1815 evtdgiVSTFNMHqqsckDL--QLYLSNLANQIDRE-TGIGDVPLVIlLDDL-------SEAGSISELVNgaltCKYHKC 1884
Cdd:NF038214  121 ------VRFTTAA-----DLveQLAQARADGRLGRLlRRLARYDLLI-IDELgylpfsrEGANLLFELIA----DRYERG 184

                         170
                  ....*....|.
gi 568908635 1885 PYIIgTTNQPV 1895
Cdd:NF038214  185 STII-TSNLPF 194
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1315-1396 3.48e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  1315 QIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQ 1394
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932


                   ..
gi 568908635  1395 GA 1396
Cdd:TIGR02168  933 GL 934
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-277 1.67e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 1.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   27 ASRPHYASSIPVPRASSQTRIHTPGASPQLRPRQQAdlalSPQRGASPRRG--KAAVSSRNSSPKAYRGRGTPRAAGPAR 104
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP----APGRVSRPRRArrLGRAAQASSPPQRPRRRAARPTVGSLT 2696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  105 ELA-----GSVESLPSSPWNSPRVTPKTALSSQAGSRRAGETQSTQRKKTQEGIPVRHTRGRSPPQSScygetqipGPPE 179
Cdd:PHA03247 2697 SLAdppppPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTA--------GPPA 2768

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  180 GRMPpgcqgkdqRNIISKPPRCLEPDEGeASGTSSPVCSPVQSMRSSATPGVISFSSAHPQSQPITATVAPFQYRLQTDQ 259
Cdd:PHA03247 2769 PAPP--------AAPAAGPPRRLTRPAV-ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP 2839

                         250
                  ....*....|....*....
gi 568908635  260 EPGPVP-QESWVLDGYTSP 277
Cdd:PHA03247 2840 PPPPGPpPPSLPLGGSVAP 2858
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 1742-1895 3.49e-05

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 47.47  E-value: 3.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1742 RRGVNNISVALK--GLK-EKCVDSLVFETL--IPKPMMQHYISL--LLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGR 1814
Cdd:NF038214   41 ERENRRIERRLKraRFPaAKTLEDFDFTAApgLDKAQIRELATLdfIERAENVLLLGPPGTGKTHLAIALGYAACRQGYR 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1815 evtdgiVSTFNMHqqsckDL--QLYLSNLANQIDRE-TGIGDVPLVIlLDDL-------SEAGSISELVNgaltCKYHKC 1884
Cdd:NF038214  121 ------VRFTTAA-----DLveQLAQARADGRLGRLlRRLARYDLLI-IDELgylpfsrEGANLLFELIA----DRYERG 184

                         170
                  ....*....|.
gi 568908635 1885 PYIIgTTNQPV 1895
Cdd:NF038214  185 STII-TSNLPF 194
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 1783-1894 1.42e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 44.29  E-value: 1.42e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   1783 KHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTdgIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDV-------- 1854
Cdd:smart00382    1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY--IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLAlalarklk 78

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|....*....
gi 568908635   1855 PLVILLDDLSEAGS---------ISELVNGALTCKYHKCPyIIGTTNQP 1894
Cdd:smart00382   79 PDVLILDEITSLLDaeqeallllLEELRLLLLLKSEKNLT-VILTTNDE 126
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1315-1396 3.48e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  1315 QIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQ 1394
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932


                   ..
gi 568908635  1395 GA 1396
Cdd:TIGR02168  933 GL 934
McrB COG1401
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ...
 1778-1808 4.71e-04

5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];


Pssm-ID: 441011 [Multi-domain]  Cd Length: 477  Bit Score: 45.15  E-value: 4.71e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 568908635 1778 ISLLLKHRRLV-LSGPSGTGKTYLTNRLAEYL 1808
Cdd:COG1401   214 FLAALKTKKNViLAGPPGTGKTYLARRLAEAL 245
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 1787-1894 5.99e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 42.52  E-value: 5.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1787 LVLSGPSGTGKTYLTNRLAEYLVERSGRevtdgiVSTFNMHQqscKDLQLYLSNLANQIDRETGIGDV----PLVILLDd 1862
Cdd:cd00009    22 LLLYGPPGTGKTTLARAIANELFRPGAP------FLYLNASD---LLEGLVVAELFGHFLVRLLFELAekakPGVLFID- 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 568908635 1863 lsEAGSISELVNGAL----------TCKYHKCPyIIGTTNQP 1894
Cdd:cd00009    92 --EIDSLSRGAQNALlrvletlndlRIDRENVR-VIGATNRP 130
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1315-1412 7.42e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 7.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1315 QIRKLRRELESSQEKVATLTSQLSANANL---------VAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKK 1385
Cdd:COG1579    60 EIKRLELEIEEVEARIKKYEEQLGNVRNNkeyealqkeIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE 139

                          90       100
                  ....*....|....*....|....*..
gi 568908635 1386 NSEAQAVIQGALNASEATPKELRIKRQ 1412
Cdd:COG1579   140 LEEKKAELDEELAELEAELEELEAERE 166
AAA_28 pfam13521
AAA domain;
1786-1818 5.30e-03

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 39.94  E-value: 5.30e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 568908635  1786 RLVLSGPSGTGKTYLTNRLAEYL----VERSGREVTD 1818
Cdd:pfam13521    1 RIVITGGPSTGKTTLAEALAARFgypvVPEAAREILE 37
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
52-237 9.35e-03

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 40.83  E-value: 9.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635    52 ASPQLRPRQQADLALSPQRGASPRRGKAAVSSRNSSPKAYRGRGTPRAAGPARELAGSveSLPSSPWNSPRvtPKTALSS 131
Cdd:pfam03546  245 APAAATPAQAKPALKTPQTKASPRKGTPITPTSAKVPPVRVGTPAPWKAGTVTSPACA--SSPAVARGAQR--PEEDSSS 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   132 QAGSRRAGETQ----STQRKKTQEGIPVrhtRGRSPPQSSCYGETQIPGPPEGRMPPGCQGKDQRNIISKPPRcLEPDEG 207
Cdd:pfam03546  321 SEESESEEETApaaaVGQAKSVGKGLQG---KAASAPTKGPSGQGTAPVPPGKTGPAVAQVKAEAQEDSESSE-EESDSE 396

                          170       180       190
                   ....*....|....*....|....*....|
gi 568908635   208 EASGTSSPVCSPVQSMRSSATPGVISFSSA 237
Cdd:pfam03546  397 EAAATPAQVKASGKTPQAKANPAPTKASSA 426
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-277 1.67e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 1.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   27 ASRPHYASSIPVPRASSQTRIHTPGASPQLRPRQQAdlalSPQRGASPRRG--KAAVSSRNSSPKAYRGRGTPRAAGPAR 104
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP----APGRVSRPRRArrLGRAAQASSPPQRPRRRAARPTVGSLT 2696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  105 ELA-----GSVESLPSSPWNSPRVTPKTALSSQAGSRRAGETQSTQRKKTQEGIPVRHTRGRSPPQSScygetqipGPPE 179
Cdd:PHA03247 2697 SLAdppppPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTA--------GPPA 2768

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  180 GRMPpgcqgkdqRNIISKPPRCLEPDEGeASGTSSPVCSPVQSMRSSATPGVISFSSAHPQSQPITATVAPFQYRLQTDQ 259
Cdd:PHA03247 2769 PAPP--------AAPAAGPPRRLTRPAV-ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP 2839

                         250
                  ....*....|....*....
gi 568908635  260 EPGPVP-QESWVLDGYTSP 277
Cdd:PHA03247 2840 PPPPGPpPPSLPLGGSVAP 2858
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 1742-1895 3.49e-05

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 47.47  E-value: 3.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1742 RRGVNNISVALK--GLK-EKCVDSLVFETL--IPKPMMQHYISL--LLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGR 1814
Cdd:NF038214   41 ERENRRIERRLKraRFPaAKTLEDFDFTAApgLDKAQIRELATLdfIERAENVLLLGPPGTGKTHLAIALGYAACRQGYR 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1815 evtdgiVSTFNMHqqsckDL--QLYLSNLANQIDRE-TGIGDVPLVIlLDDL-------SEAGSISELVNgaltCKYHKC 1884
Cdd:NF038214  121 ------VRFTTAA-----DLveQLAQARADGRLGRLlRRLARYDLLI-IDELgylpfsrEGANLLFELIA----DRYERG 184

                         170
                  ....*....|.
gi 568908635 1885 PYIIgTTNQPV 1895
Cdd:NF038214  185 STII-TSNLPF 194
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 1783-1894 1.42e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 44.29  E-value: 1.42e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   1783 KHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTdgIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDV-------- 1854
Cdd:smart00382    1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY--IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLAlalarklk 78

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|....*....
gi 568908635   1855 PLVILLDDLSEAGS---------ISELVNGALTCKYHKCPyIIGTTNQP 1894
Cdd:smart00382   79 PDVLILDEITSLLDaeqeallllLEELRLLLLLKSEKNLT-VILTTNDE 126
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1315-1396 3.48e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  1315 QIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQ 1394
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932


                   ..
gi 568908635  1395 GA 1396
Cdd:TIGR02168  933 GL 934
PHA03247 PHA03247
large tegument protein UL36; Provisional
 8-286 3.90e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 3.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635    8 PSAALPLLLTMSGMANVNSASRPHYASSIP--VPRASSQTRIHTPGASPQL-----RPRQQADLALSPQRGASPRRGKAA 80
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQASPALPAAPAPpaVPAGPATPGGPARPARPPTtagppAPAPPAAPAAGPPRRLTRPAVASL 2791

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   81 VSSRNSSPKAY-----------RGRGTPRAAGPARELAGSVESLPSSPWNSPRVTPKT-----ALSSQAGSRRAGETQST 144
Cdd:PHA03247 2792 SESRESLPSPWdpadppaavlaPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggSVAPGGDVRRRPPSRSP 2871

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  145 QRKKTQEGIPVRHTRGRSPPQSSCYGETQIPGPPEGRMPPGCQGKDQrniiskPPRCLEPDEGEASGTSSPVCSPVQSMR 224
Cdd:PHA03247 2872 AAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQ------PQPQPPPPPQPQPPPPPPPRPQPPLAP 2945

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568908635  225 SSATPGVISFSSAHPqsQPITATVAPFQYRLQTDQEPGPVPQeswVLDGYTSPPSRTEDSFS 286
Cdd:PHA03247 2946 TTDPAGAGEPSGAVP--QPWLGALVPGRVAVPRFRVPQPAPS---REAPASSTPPLTGHSLS 3002
PHA03378 PHA03378
EBNA-3B; Provisional
 22-253 4.14e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 45.44  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   22 ANVNSASRPHYASSIPVPRASSQTRIHTPGASPQLRPRQQADLALSPQRGASPRRGK--AAVSSRNSSPKAYRGRGTPRA 99
Cdd:PHA03378  679 TGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARppAAAPGRARPPAAAPGRARPPA 758

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  100 AGPARELAGSVESLPSSPWNSPRVTPKTALSSQAGSrraGETQSTQRKKTQEGIPVRHTRGRSPPQSSCYGETQIPGPPE 179
Cdd:PHA03378  759 AAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAP---TPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGGVKR 835

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  180 GRMPPGCQGKDQRniisKPPRCLEPDEGeaSGTSS----------PVCSPVQSMRSSATPGVISFSsahpqsqpiTATVA 249
Cdd:PHA03378  836 GRPSLKKPAALER----QAAAGPTPSPG--SGTSDkivqapvfypPVLQPIQVMRQLGSVRAAAAS---------TVTQA 900


                  ....
gi 568908635  250 PFQY 253
Cdd:PHA03378  901 PTEY 904
McrB COG1401
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ...
 1778-1808 4.71e-04

5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];


Pssm-ID: 441011 [Multi-domain]  Cd Length: 477  Bit Score: 45.15  E-value: 4.71e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 568908635 1778 ISLLLKHRRLV-LSGPSGTGKTYLTNRLAEYL 1808
Cdd:COG1401   214 FLAALKTKKNViLAGPPGTGKTYLARRLAEAL 245
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 1787-1894 5.99e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 42.52  E-value: 5.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1787 LVLSGPSGTGKTYLTNRLAEYLVERSGRevtdgiVSTFNMHQqscKDLQLYLSNLANQIDRETGIGDV----PLVILLDd 1862
Cdd:cd00009    22 LLLYGPPGTGKTTLARAIANELFRPGAP------FLYLNASD---LLEGLVVAELFGHFLVRLLFELAekakPGVLFID- 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 568908635 1863 lsEAGSISELVNGAL----------TCKYHKCPyIIGTTNQP 1894
Cdd:cd00009    92 --EIDSLSRGAQNALlrvletlndlRIDRENVR-VIGATNRP 130
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1315-1412 7.42e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 7.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1315 QIRKLRRELESSQEKVATLTSQLSANANL---------VAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKK 1385
Cdd:COG1579    60 EIKRLELEIEEVEARIKKYEEQLGNVRNNkeyealqkeIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE 139

                          90       100
                  ....*....|....*....|....*..
gi 568908635 1386 NSEAQAVIQGALNASEATPKELRIKRQ 1412
Cdd:COG1579   140 LEEKKAELDEELAELEAELEELEAERE 166
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1315-1412 3.24e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 3.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1315 QIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETidflKKKNSEAQAVIQ 1394
Cdd:COG4372    67 ELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQ----RKQLEAQIAELQ 142

                          90
                  ....*....|....*...
gi 568908635 1395 GALNASEATPKELRIKRQ 1412
Cdd:COG4372   143 SEIAEREEELKELEEQLE 160
AAA_28 pfam13521
AAA domain;
1786-1818 5.30e-03

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 39.94  E-value: 5.30e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 568908635  1786 RLVLSGPSGTGKTYLTNRLAEYL----VERSGREVTD 1818
Cdd:pfam13521    1 RIVITGGPSTGKTTLAEALAARFgypvVPEAAREILE 37
PHA03247 PHA03247
large tegument protein UL36; Provisional
 24-278 5.92e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   24 VNSASRPHYASSIP---VPRA--------SSQTRIHTPGASPQLRPR-----------QQADLALSPQRGASP------- 74
Cdd:PHA03247 2667 ARRLGRAAQASSPPqrpRRRAarptvgslTSLADPPPPPPTPEPAPHalvsatplppgPAAARQASPALPAAPappavpa 2746

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   75 ---------RRGKAAVSSRNSSPKAYRGR-GTPRAAGPARELAGSVESLPSSPWNSPRVTPKTALSSQAGSRRAGETQST 144
Cdd:PHA03247 2747 gpatpggpaRPARPPTTAGPPAPAPPAAPaAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  145 QRKKTQEGIPVRHTRGRSPPQSSCygetqipgPPEGRMPPGcqGKDQRNIISKPPrclepdegeASGTSSPVCSPVQSM- 223
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGPPPPSL--------PLGGSVAPG--GDVRRRPPSRSP---------AAKPAAPARPPVRRLa 2887

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568908635  224 RSSATPGVISFSSAHPQSQPITATVAPFQYRLQTDQEPGPVPQESWVLDGYTSPP 278
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
PHA03247 PHA03247
large tegument protein UL36; Provisional
 49-265 7.55e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 7.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   49 TPGASPQLRPrQQADLALSPQRGAsPRRGKAAVSSRNSSPKAYRGRGTPRAAG-PARELAGSVESLPSSPWNSPRVTPKT 127
Cdd:PHA03247 2552 PPPLPPAAPP-AAPDRSVPPPRPA-PRPSEPAVTSRARRPDAPPQSARPRAPVdDRGDPRGPAPPSPLPPDTHAPDPPPP 2629

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  128 ALSSQAGSRRAGETQSTQRKKTQEGIPV-----RHTRGRSPPQSscygeTQIPGPPEGRMPPGCQGK--DQRNIISKPPR 200
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPApgrvsRPRRARRLGRA-----AQASSPPQRPRRRAARPTvgSLTSLADPPPP 2704

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568908635  201 CLEPDEGEASGTSS-PVCSPVQSMRSSATPGVISFSSAHPQSQPIT-ATVAPFQYRLQTDQEPGPVP 265
Cdd:PHA03247 2705 PPTPEPAPHALVSAtPLPPGPAAARQASPALPAAPAPPAVPAGPATpGGPARPARPPTTAGPPAPAP 2771
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1315-1408 8.79e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 8.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635 1315 QIRKLRRELESSQEKVATLTSQLSANANL--VAAFEQSLVNMTSRLRHLaetaEEKDTELLDLRETIDFLKKKNSEAQAV 1392
Cdd:COG4717   103 ELEELEAELEELREELEKLEKLLQLLPLYqeLEALEAELAELPERLEEL----EERLEELRELEEELEELEAELAELQEE 178

                          90
                  ....*....|....*..
gi 568908635 1393 IQGALN-ASEATPKELR 1408
Cdd:COG4717   179 LEELLEqLSLATEEELQ 195
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
52-237 9.35e-03

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 40.83  E-value: 9.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635    52 ASPQLRPRQQADLALSPQRGASPRRGKAAVSSRNSSPKAYRGRGTPRAAGPARELAGSveSLPSSPWNSPRvtPKTALSS 131
Cdd:pfam03546  245 APAAATPAQAKPALKTPQTKASPRKGTPITPTSAKVPPVRVGTPAPWKAGTVTSPACA--SSPAVARGAQR--PEEDSSS 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   132 QAGSRRAGETQ----STQRKKTQEGIPVrhtRGRSPPQSSCYGETQIPGPPEGRMPPGCQGKDQRNIISKPPRcLEPDEG 207
Cdd:pfam03546  321 SEESESEEETApaaaVGQAKSVGKGLQG---KAASAPTKGPSGQGTAPVPPGKTGPAVAQVKAEAQEDSESSE-EESDSE 396

                          170       180       190
                   ....*....|....*....|....*....|
gi 568908635   208 EASGTSSPVCSPVQSMRSSATPGVISFSSA 237
Cdd:pfam03546  397 EAAATPAQVKASGKTPQAKANPAPTKASSA 426
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 5-277 9.40e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 9.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635    5 TQDPSAALPLLLTMSGMANVNSASRPHYASSIPVPRASSQTRIHTPGASPQLRPR----QQADLALSPQRGASPRRGKAA 80
Cdd:PHA03307  155 AGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRsspiSASASSPAPAPGRSAADDAGA 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635   81 VSSRNSSPKAYRGRGTPRAAGPaRELAGSVESLPS----SPWNSPRVTPKTALSSQAGSRRAGETQSTQRKKTQEGIPVR 156
Cdd:PHA03307  235 SSSDSSSSESSGCGWGPENECP-LPRPAPITLPTRiweaSGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908635  157 HTRGRSPPQSSCYGETQIPGPPEGRMPPGcqgkdqrniiSKPPRCLEPDEGEASGtSSPVCSPVQSMRSSATPGVISFSS 236
Cdd:PHA03307  314 ASSSSSSSRESSSSSTSSSSESSRGAAVS----------PGPSPSRSPSPSRPPP-PADPSSPRKRPRPSRAPSSPAASA 382

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 568908635  237 AHPQSQPITATVAPFQYRLQ-TDQEPGPVPQESWVLDGYTSP 277
Cdd:PHA03307  383 GRPTRRRARAAVAGRARRRDaTGRFPAGRPRPSPLDAGAASG 424
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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