F-box only protein 40 isoform X1 [Mus musculus]
F-box protein( domain architecture ID 11240040)
F-box protein containing a TRAF-like zinc-finger, may function as the substrate-recognition component of a SCF(Skp1-cullin-F-box) E3 ubiquitin ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins
List of domain hits
Name | Accession | Description | Interval | E-value | |||
F-box_4 | pfam15966 | F-box; |
571-686 | 4.27e-67 | |||
F-box; : Pssm-ID: 464958 Cd Length: 116 Bit Score: 216.00 E-value: 4.27e-67
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zf-TRAF_2 | pfam15965 | TRAF-like zinc-finger; |
12-103 | 3.33e-58 | |||
TRAF-like zinc-finger; : Pssm-ID: 464957 Cd Length: 92 Bit Score: 191.39 E-value: 3.33e-58
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Name | Accession | Description | Interval | E-value | |||
F-box_4 | pfam15966 | F-box; |
571-686 | 4.27e-67 | |||
F-box; Pssm-ID: 464958 Cd Length: 116 Bit Score: 216.00 E-value: 4.27e-67
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zf-TRAF_2 | pfam15965 | TRAF-like zinc-finger; |
12-103 | 3.33e-58 | |||
TRAF-like zinc-finger; Pssm-ID: 464957 Cd Length: 92 Bit Score: 191.39 E-value: 3.33e-58
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F-box_FBXO40 | cd22175 | F-box domain found in F-box only protein 40 (FBXO40) and similar proteins; FBXO40, also called ... |
575-623 | 1.64e-24 | |||
F-box domain found in F-box only protein 40 (FBXO40) and similar proteins; FBXO40, also called FBX40, or muscle disease-related protein, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438946 Cd Length: 49 Bit Score: 96.50 E-value: 1.64e-24
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Name | Accession | Description | Interval | E-value | |||
F-box_4 | pfam15966 | F-box; |
571-686 | 4.27e-67 | |||
F-box; Pssm-ID: 464958 Cd Length: 116 Bit Score: 216.00 E-value: 4.27e-67
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zf-TRAF_2 | pfam15965 | TRAF-like zinc-finger; |
12-103 | 3.33e-58 | |||
TRAF-like zinc-finger; Pssm-ID: 464957 Cd Length: 92 Bit Score: 191.39 E-value: 3.33e-58
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F-box_FBXO40 | cd22175 | F-box domain found in F-box only protein 40 (FBXO40) and similar proteins; FBXO40, also called ... |
575-623 | 1.64e-24 | |||
F-box domain found in F-box only protein 40 (FBXO40) and similar proteins; FBXO40, also called FBX40, or muscle disease-related protein, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438946 Cd Length: 49 Bit Score: 96.50 E-value: 1.64e-24
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F-box_FBXO30-like | cd22101 | F-box domain found in F-box only protein 30 (FBXO30), F-box only protein 40 (FBXO40) and ... |
575-619 | 4.81e-19 | |||
F-box domain found in F-box only protein 30 (FBXO30), F-box only protein 40 (FBXO40) and similar proteins; FBXO30, also called FBX30, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is required for muscle atrophy following denervation. FBXO30 regulates mammopoiesis by targeting the bipolar mitotic kinesin Eg5. FBXO40, also called FBX40, or muscle disease-related protein, is a probable substrate-recognition component of an SCF-type E3 ubiquitin ligase complex that may function in myogenesis. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438873 Cd Length: 45 Bit Score: 80.88 E-value: 4.81e-19
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F-box_FBXO30 | cd22174 | F-box domain found in F-box only protein 30 (FBXO30) and similar proteins; FBXO30, also called ... |
575-623 | 6.43e-17 | |||
F-box domain found in F-box only protein 30 (FBXO30) and similar proteins; FBXO30, also called FBX30, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is required for muscle atrophy following denervation. FBXO30 regulates mammopoiesis by targeting the bipolar mitotic kinesin Eg5. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438945 Cd Length: 49 Bit Score: 74.92 E-value: 6.43e-17
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F-box_SF | cd09917 | F-box domain superfamily; This short domain is commonly found at the N-terminus of various ... |
576-609 | 3.98e-04 | |||
F-box domain superfamily; This short domain is commonly found at the N-terminus of various proteins, and typically co-occurs with one or more other conserved domains or motifs, such as leucine rich repeats, WD40 repeats, kelch, tub, spry, and others. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. One of the best researched roles of F-box proteins is their participation in SCF (Skp1-Cul1-F-box protein), a multi-protein complex that functions as a ubiquitin E3 ligase, where the role of the F-box protein is to recruit target substrates. Gene families containing the F-box are found greatly expanded in narrow taxonomic lineages, such as flowering plants and nematodes. In this hierarchical classification, many of the subfamilies are named according to their domain architectures. Pssm-ID: 438852 Cd Length: 35 Bit Score: 38.19 E-value: 3.98e-04
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F-box_FBXL4 | cd22117 | F-box domain found in F-box/LRR-repeat protein 4 (FBXL4) and similar proteins; FBXL4, also ... |
578-614 | 4.22e-04 | |||
F-box domain found in F-box/LRR-repeat protein 4 (FBXL4) and similar proteins; FBXL4, also called F-box and leucine-rich repeat protein 4, or F-box protein FBL4/FBL5, is part of an SCF (SKP1-cullin-F-box) protein ligase complex. It serves as a clock output molecule that regulates sleep through promotion of rhythmic degradation of the GABA(A) receptor. Biallelic pathogenic variants in FBXL4 are associated with an encephalopathic mtDNA maintenance defect syndrome that is a multi-system disease characterized by lactic acidemia, developmental delay, and hypotonia. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438889 Cd Length: 47 Bit Score: 38.37 E-value: 4.22e-04
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Blast search parameters | ||||
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