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Conserved domains on  [gi|568967333|ref|XP_006513601|]
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zinc finger C3H1 domain-containing protein isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1368-1699 7.05e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 7.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1368 WLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPdyQSFWTFLHL 1447
Cdd:COG2956    11 WYFKGLNYLLNGQ------PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDP--DRAEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1448 -ESTFEEKDYvcERMVEFLMGAAKREISDIlsfqllEALLFRVQLHIFTGRCQSALAVLQNALKLANDAIVAEYLktddr 1526
Cdd:COG2956    83 aQDYLKAGLL--DRAEELLEKLLELDPDDA------EALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCE----- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1527 clawLAYIHLiefnslpsklydpsnanpsrivntepfvmpwqaAQDvktNPDLLLAVFEDAVKACTDetltsgerievCL 1606
Cdd:COG2956   150 ----LAELYL---------------------------------EQG---DYDEAIEALEKALKLDPD-----------CA 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1607 PLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYhLCKFFIL 1686
Cdd:COG2956   179 RALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLER 257

                         330
                  ....*....|...
gi 568967333 1687 QDGGDKLLPVLRQ 1699
Cdd:COG2956   258 KEGLEAALALLER 270
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 827-1001 3.52e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  827 TKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMFLKKLQEQIHRVQQR 906
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  907 VTIKKaltlkygEELARAKAVASKeLGKRKLEQDRLGPN------KMMRLDNSpISSPRKHSAELIAMEKRRLQKLEYEY 980
Cdd:COG4942    99 LEAQK-------EELAELLRALYR-LGRQPPLALLLSPEdfldavRRLQYLKY-LAPARREQAEELRADLAELAALRAEL 169

                         170       180
                  ....*....|....*....|.
gi 568967333  981 ALKIQKLKEARALKAKEQQNL 1001
Cdd:COG4942   170 EAERAELEALLAELEEERAAL 190
PTZ00121 super family cl31754
MAEBL; Provisional
 744-1097 7.27e-06

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 7.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  744 EARRTAEQASKPKVPPKseKENDPLRTPEA----LPEEKKMEYRLLKEEIANREKQRLIKSDQLKTSssspANSDVEMDG 819
Cdd:PTZ00121 1388 EEKKKADEAKKKAEEDK--KKADELKKAAAakkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK----AEEAKKAEE 1461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  820 IGRIAMVTKQVADAEAKLKKHKilliKDESVLKNLvlQEAKKK--ESVRNAEAKitKLTEQLQAAEKILSANRmfLKKLQ 897
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAK----KADEAKKKA--EEAKKKadEAKKAAEAK--KKADEAKKAEEAKKADE--AKKAE 1531

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  898 E--QIHRVQQRVTIKKALTLKYGEELARAKAVASKElGKRKLEQDRLGPNK----MMRLDNSPISSPRKHSAELIAMEKR 971
Cdd:PTZ00121 1532 EakKADEAKKAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEEDKNMALRkaeeAKKAEEARIEEVMKLYEEEKKMKAE 1610

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  972 RLQKLEyEYALKIQKLKEARALKAKEQQNLVPVVEEEPEfsvpqpslhdltQDKLTLDTEENDVDDEVLSGASRERRRSF 1051
Cdd:PTZ00121 1611 EAKKAE-EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK------------AEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 568967333 1052 LESNSFTKPNLKHTDTPNKECINKLSKSTVEKPELFLGLKIGELQK 1097
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723
zf-C3H1 pfam10650
Putative zinc-finger domain; This domain is conserved in fungi and might be a zinc-finger ...
 1189-1208 9.33e-06

Putative zinc-finger domain; This domain is conserved in fungi and might be a zinc-finger domain as it contains three conserved Cs and an H in the C-x8-C-x5-C-x3-H conformation typical of a zinc-finger.


:

Pssm-ID: 431418  Cd Length: 22  Bit Score: 43.72  E-value: 9.33e-06
                           10        20
                   ....*....|....*....|.
gi 568967333  1189 FCRFDLTG-TCNDDDCQWQHV 1208
Cdd:pfam10650    1 LCPYELAGgVCNDPSCEFQHF 21
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 201-998 9.47e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member pfam02463:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1161  Bit Score: 47.66  E-value: 9.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   201 RKSSKSFGRSPSRKQNHSSKSENCAEETFEDLLLKYKQIQLELEciNKDEKLALSSKEETAQEdpKTLHLEDQTSTDNAS 280
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKK--LQEEELKLLAKEEEELK--SELLKLERRKVDDEE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   281 ITKDPSKEVAPEEKTQVKTFQAFELKpLRQKLTLPGDKNRVKRGKDGTRQLSLKSSTtdASQGLEDKEQNLTRRLSASDI 360
Cdd:pfam02463  315 KLKESEKEKKKAEKELKKEKEEIEEL-EKELKELEIKREAEEEEEEELEKLQEKLEQ--LEEELLAKKKLESERLSSAAK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   361 VSEKKLGEEEEELSelqlrllALQSASKKWQQKEQQVMKESKEKLTKTKTaQQKAKTSTKAHSAKKVSATAKQALRKQQT 440
Cdd:pfam02463  392 LKEEELELKSEEEK-------EAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLKD 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   441 KAWKKLQQQKEQERQKEEDQRKHAEEEERRKREEEIRKirdLSNQEEQYNRFMKLVGGKRRARSKSSDPDLRRSLEKQSD 520
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   521 SAGGIYQYDNYEEVAMDTDSETsspaAPSPVQPPFFPECSLGYFSSAPSVSLPPPAQVSSVPSLNQPYGEGLCVSLDPLP 600
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEE----RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   601 PLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREEllKSLASKRAFKpeETSSNSDPPSPPVLNNSQPLSRSNLSIVSIN 680
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG--VSLEEGLAEK--SEVKASLSELTKELLEIQELQEKAESELAKE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   681 TV-SQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGG-LESMIKEARRTAEQASKPKVP 758
Cdd:pfam02463  693 EIlRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEeEEKSRLKKEEKEEEKSELSLK 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   759 PKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRLIK------SDQLKTSSSSPANSDVEMDGIGRIAMVTKQVAD 832
Cdd:pfam02463  773 EKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEaelleeEQLLIEQEEKIKEEELEELALELKEEQKLEKLA 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   833 AEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMflkkLQEQIHRVQQRVTIKKA 912
Cdd:pfam02463  853 EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL----LEEKENEIEERIKEEAE 928

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   913 LTLKYGEELARAKAVASKElgKRKLEQDRLGPNKMMRLDNSPISSPRKHSAELIaMEKRRLQKLEYEYALKIQKLKEARA 992
Cdd:pfam02463  929 ILLKYEEEPEELLLEEADE--KEKEENNKEEEEERNKRLLLAKEELGKVNLMAI-EEFEEKEERYNKDELEKERLEEEKK 1005


                   ....*.
gi 568967333   993 LKAKEQ 998
Cdd:pfam02463 1006 KLIRAI 1011
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1368-1699 7.05e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 7.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1368 WLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPdyQSFWTFLHL 1447
Cdd:COG2956    11 WYFKGLNYLLNGQ------PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDP--DRAEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1448 -ESTFEEKDYvcERMVEFLMGAAKREISDIlsfqllEALLFRVQLHIFTGRCQSALAVLQNALKLANDAIVAEYLktddr 1526
Cdd:COG2956    83 aQDYLKAGLL--DRAEELLEKLLELDPDDA------EALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCE----- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1527 clawLAYIHLiefnslpsklydpsnanpsrivntepfvmpwqaAQDvktNPDLLLAVFEDAVKACTDetltsgerievCL 1606
Cdd:COG2956   150 ----LAELYL---------------------------------EQG---DYDEAIEALEKALKLDPD-----------CA 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1607 PLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYhLCKFFIL 1686
Cdd:COG2956   179 RALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLER 257

                         330
                  ....*....|...
gi 568967333 1687 QDGGDKLLPVLRQ 1699
Cdd:COG2956   258 KEGLEAALALLER 270
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 827-1001 3.52e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  827 TKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMFLKKLQEQIHRVQQR 906
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  907 VTIKKaltlkygEELARAKAVASKeLGKRKLEQDRLGPN------KMMRLDNSpISSPRKHSAELIAMEKRRLQKLEYEY 980
Cdd:COG4942    99 LEAQK-------EELAELLRALYR-LGRQPPLALLLSPEdfldavRRLQYLKY-LAPARREQAEELRADLAELAALRAEL 169

                         170       180
                  ....*....|....*....|.
gi 568967333  981 ALKIQKLKEARALKAKEQQNL 1001
Cdd:COG4942   170 EAERAELEALLAELEEERAAL 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 738-1010 3.77e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 3.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   738 LESMIKEARRTAEQASKpkvppKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEM 817
Cdd:TIGR02168  710 LEEELEQLRKELEELSR-----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   818 --------DGIGRIAMVTKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSAN 889
Cdd:TIGR02168  785 eeleaqieQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   890 RMFLKKLQEQIHRVQQRVtikkaltlkygEELARAKAVASKELGKRKLEQDRLGpNKMMRLDNSpisspRKHSAELIAME 969
Cdd:TIGR02168  865 EELIEELESELEALLNER-----------ASLEEALALLRSELEELSEELRELE-SKRSELRRE-----LEELREKLAQL 927

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 568967333   970 KRRLQKLEYEYALKIQKLKEARALKAKEQQNLVPVVEEEPE 1010
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968
PTZ00121 PTZ00121
MAEBL; Provisional
 744-1097 7.27e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 7.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  744 EARRTAEQASKPKVPPKseKENDPLRTPEA----LPEEKKMEYRLLKEEIANREKQRLIKSDQLKTSssspANSDVEMDG 819
Cdd:PTZ00121 1388 EEKKKADEAKKKAEEDK--KKADELKKAAAakkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK----AEEAKKAEE 1461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  820 IGRIAMVTKQVADAEAKLKKHKilliKDESVLKNLvlQEAKKK--ESVRNAEAKitKLTEQLQAAEKILSANRmfLKKLQ 897
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAK----KADEAKKKA--EEAKKKadEAKKAAEAK--KKADEAKKAEEAKKADE--AKKAE 1531

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  898 E--QIHRVQQRVTIKKALTLKYGEELARAKAVASKElGKRKLEQDRLGPNK----MMRLDNSPISSPRKHSAELIAMEKR 971
Cdd:PTZ00121 1532 EakKADEAKKAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEEDKNMALRkaeeAKKAEEARIEEVMKLYEEEKKMKAE 1610

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  972 RLQKLEyEYALKIQKLKEARALKAKEQQNLVPVVEEEPEfsvpqpslhdltQDKLTLDTEENDVDDEVLSGASRERRRSF 1051
Cdd:PTZ00121 1611 EAKKAE-EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK------------AEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 568967333 1052 LESNSFTKPNLKHTDTPNKECINKLSKSTVEKPELFLGLKIGELQK 1097
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723
PTZ00121 PTZ00121
MAEBL; Provisional
 743-1080 7.84e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 7.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  743 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRliKSDQLKTSSSSPANSDVEMDGIGR 822
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK--KADELKKAEELKKAEEKKKAEEAK 1570

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  823 IAMVTKQVADAEAKLKKhKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKlTEQLQAAEKILSANRMFLKKLQEQihr 902
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAK-KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK-AEELKKAEEEKKKVEQLKKKEAEE--- 1645

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  903 vqqrvtIKKALTLKYGEELARAKavasKELGKRKLEQDRLGPNKMMRLDNSpisspRKHSAELIAMEKRRLQKLEYEYAL 982
Cdd:PTZ00121 1646 ------KKKAEELKKAEEENKIK----AAEEAKKAEEDKKKAEEAKKAEED-----EKKAAEALKKEAEEAKKAEELKKK 1710

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  983 KIQKLKEARALKAKEQQNLVPVVEEEPEFSVPQPSLHDLTQDKltldtEENDVDDEVLSGASRERRRSFLESNSFTKPNL 1062
Cdd:PTZ00121 1711 EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDE-----EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785

                         330
                  ....*....|....*...
gi 568967333 1063 KHTDTPNKECINKLSKST 1080
Cdd:PTZ00121 1786 DEEDEKRRMEVDKKIKDI 1803
zf-C3H1 pfam10650
Putative zinc-finger domain; This domain is conserved in fungi and might be a zinc-finger ...
 1189-1208 9.33e-06

Putative zinc-finger domain; This domain is conserved in fungi and might be a zinc-finger domain as it contains three conserved Cs and an H in the C-x8-C-x5-C-x3-H conformation typical of a zinc-finger.


Pssm-ID: 431418  Cd Length: 22  Bit Score: 43.72  E-value: 9.33e-06
                           10        20
                   ....*....|....*....|.
gi 568967333  1189 FCRFDLTG-TCNDDDCQWQHV 1208
Cdd:pfam10650    1 LCPYELAGgVCNDPSCEFQHF 21
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 737-1035 6.15e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.97  E-value: 6.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   737 GLESMIKEARRTAEQaSKPKVPPKSEKENDPLRTPEALPEEKKMeyrLLKEEIANREKQRLIKSDqLKTSSSSPANSDVE 816
Cdd:pfam07888   77 ELESRVAELKEELRQ-SREKHEELEEKYKELSASSEELSEEKDA---LLAQRAAHEARIRELEED-IKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   817 MDGIG-RIAMVTKQVADAEAKLKKHKILLIKDESVLKNLV--LQEAKKKESVRNAEA-----KITKLTEQLQAAEKILSA 888
Cdd:pfam07888  152 LERMKeRAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSkeFQELRNSLAQRDTQVlqlqdTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   889 NRMFLKKL---QEQIHRVQQRVTIkkaltlkYGEELAraKAVASKELGKRKLEQDRLGPNKM----------MRLDNSPI 955
Cdd:pfam07888  232 NEALLEELrslQERLNASERKVEG-------LGEELS--SMAAQRDRTQAELHQARLQAAQLtlqladaslaLREGRARW 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   956 SSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAK--------EQQNLVPVVEEEPEFSVPQPSLHDLTQDKLT 1027
Cdd:pfam07888  303 AQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKlevelgreKDCNRVQLSESRRELQELKASLRVAQKEKEQ 382


                   ....*...
gi 568967333  1028 LDTEENDV 1035
Cdd:pfam07888  383 LQAEKQEL 390
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 201-998 9.47e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.66  E-value: 9.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   201 RKSSKSFGRSPSRKQNHSSKSENCAEETFEDLLLKYKQIQLELEciNKDEKLALSSKEETAQEdpKTLHLEDQTSTDNAS 280
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKK--LQEEELKLLAKEEEELK--SELLKLERRKVDDEE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   281 ITKDPSKEVAPEEKTQVKTFQAFELKpLRQKLTLPGDKNRVKRGKDGTRQLSLKSSTtdASQGLEDKEQNLTRRLSASDI 360
Cdd:pfam02463  315 KLKESEKEKKKAEKELKKEKEEIEEL-EKELKELEIKREAEEEEEEELEKLQEKLEQ--LEEELLAKKKLESERLSSAAK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   361 VSEKKLGEEEEELSelqlrllALQSASKKWQQKEQQVMKESKEKLTKTKTaQQKAKTSTKAHSAKKVSATAKQALRKQQT 440
Cdd:pfam02463  392 LKEEELELKSEEEK-------EAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLKD 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   441 KAWKKLQQQKEQERQKEEDQRKHAEEEERRKREEEIRKirdLSNQEEQYNRFMKLVGGKRRARSKSSDPDLRRSLEKQSD 520
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   521 SAGGIYQYDNYEEVAMDTDSETsspaAPSPVQPPFFPECSLGYFSSAPSVSLPPPAQVSSVPSLNQPYGEGLCVSLDPLP 600
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEE----RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   601 PLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREEllKSLASKRAFKpeETSSNSDPPSPPVLNNSQPLSRSNLSIVSIN 680
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG--VSLEEGLAEK--SEVKASLSELTKELLEIQELQEKAESELAKE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   681 TV-SQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGG-LESMIKEARRTAEQASKPKVP 758
Cdd:pfam02463  693 EIlRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEeEEKSRLKKEEKEEEKSELSLK 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   759 PKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRLIK------SDQLKTSSSSPANSDVEMDGIGRIAMVTKQVAD 832
Cdd:pfam02463  773 EKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEaelleeEQLLIEQEEKIKEEELEELALELKEEQKLEKLA 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   833 AEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMflkkLQEQIHRVQQRVTIKKA 912
Cdd:pfam02463  853 EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL----LEEKENEIEERIKEEAE 928

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   913 LTLKYGEELARAKAVASKElgKRKLEQDRLGPNKMMRLDNSPISSPRKHSAELIaMEKRRLQKLEYEYALKIQKLKEARA 992
Cdd:pfam02463  929 ILLKYEEEPEELLLEEADE--KEKEENNKEEEEERNKRLLLAKEELGKVNLMAI-EEFEEKEERYNKDELEKERLEEEKK 1005


                   ....*.
gi 568967333   993 LKAKEQ 998
Cdd:pfam02463 1006 KLIRAI 1011
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 1621-1671 3.70e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.93  E-value: 3.70e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568967333 1621 RYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNP 1671
Cdd:cd24142    15 NFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1354-1682 4.48e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 4.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1354 LEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVE 1433
Cdd:TIGR02917  556 LEKAAELNPQEIEPALALAQYYLGKGQ------LKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLA 629

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1434 YAPD-----------YQSF------WTFLHLESTFEEKDYVCERMVEFLMGAAKREISDILSFQLLE------ALLFRV- 1489
Cdd:TIGR02917  630 LQPDsalalllladaYAVMknyakaITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQkqhpkaALGFELe 709

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1490 -QLHIFTGRCQSALAVLQNALKLANDAIVAEYL-----------KTDDRCLAWLAyihliefnslpsklyDPSNANPSRI 1557
Cdd:TIGR02917  710 gDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLhrallasgntaEAVKTLEAWLK---------------THPNDAVLRT 774

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1558 VNTEPFVMPWQAAQDVKtnpdlllaVFEDAVKACTDetltsgerievclplytNMIALHQL----LERYE-EAVELCTSL 1632
Cdd:TIGR02917  775 ALAELYLAQKDYDKAIK--------HYQTVVKKAPD-----------------NAVVLNNLawlyLELKDpRALEYAERA 829

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 568967333  1633 LESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCK 1682
Cdd:TIGR02917  830 LKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879
TPR_12 pfam13424
Tetratricopeptide repeat;
1608-1661 6.67e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.37  E-value: 6.67e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568967333  1608 LYTNMIALHQLLERYEEAVELCTSLLESC--------PTNCQLLETLAALYLKTDRYDKARR 1661
Cdd:pfam13424    5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALE 66
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1368-1699 7.05e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 7.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1368 WLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPdyQSFWTFLHL 1447
Cdd:COG2956    11 WYFKGLNYLLNGQ------PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDP--DRAEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1448 -ESTFEEKDYvcERMVEFLMGAAKREISDIlsfqllEALLFRVQLHIFTGRCQSALAVLQNALKLANDAIVAEYLktddr 1526
Cdd:COG2956    83 aQDYLKAGLL--DRAEELLEKLLELDPDDA------EALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCE----- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1527 clawLAYIHLiefnslpsklydpsnanpsrivntepfvmpwqaAQDvktNPDLLLAVFEDAVKACTDetltsgerievCL 1606
Cdd:COG2956   150 ----LAELYL---------------------------------EQG---DYDEAIEALEKALKLDPD-----------CA 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1607 PLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYhLCKFFIL 1686
Cdd:COG2956   179 RALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLER 257

                         330
                  ....*....|...
gi 568967333 1687 QDGGDKLLPVLRQ 1699
Cdd:COG2956   258 KEGLEAALALLER 270
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1351-1445 1.36e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.79  E-value: 1.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG4235     3 IARLRQALAANPNDAEGWLLLGRAYLRLGR------YDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLER 76

                          90
                  ....*....|....*
gi 568967333 1431 AVEYAPDYQSFWTFL 1445
Cdd:COG4235    77 ALALDPDNPEALYLL 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1567-1699 1.01e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.12  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1567 WQAAQDVKTNPDLLLAVFEDAVKACTDETLTSGERIEVCLPLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETL 1646
Cdd:COG5010    15 LLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL 94

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568967333 1647 AALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCKFFILQDGGDKLLPVLRQ 1699
Cdd:COG5010    95 ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1576-1701 1.05e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1576 NPDLLLAVFEDAVKACTDEtltsgerievcLPLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDR 1655
Cdd:COG2956    23 QPDKAIDLLEEALELDPET-----------VEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568967333 1656 YDKARRVWLTAFENNPQNAEIFYHLCKFFILQDGGDKLLPVLRQFV 1701
Cdd:COG2956    92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLL 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1609-1699 2.66e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 2.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1609 YTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCKFFILQD 1688
Cdd:COG0457    79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                          90
                  ....*....|.
gi 568967333 1689 GGDKLLPVLRQ 1699
Cdd:COG0457   159 RYEEALELLEK 169
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1605-1691 4.65e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.00  E-value: 4.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1605 CLPLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCkfF 1684
Cdd:COG3914   111 NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLG--N 188


                  ....*..
gi 568967333 1685 ILQDGGD 1691
Cdd:COG3914   189 ALQDLGR 195
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1606-1691 4.82e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.00  E-value: 4.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1606 LPLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCkfFI 1685
Cdd:COG3914   146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLL--FA 223


                  ....*.
gi 568967333 1686 LQDGGD 1691
Cdd:COG3914   224 LRQACD 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1609-1680 7.43e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 7.43e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568967333 1609 YTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHL 1680
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1605-1699 1.23e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1605 CLPLYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCKFF 1684
Cdd:COG4783     3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                          90
                  ....*....|....*
gi 568967333 1685 ILQDGGDKLLPVLRQ 1699
Cdd:COG4783    83 LKAGDYDEALALLEK 97
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1614-1724 1.28e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.04  E-value: 1.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1614 ALHQLL-ERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCKFFILQDGGDK 1692
Cdd:COG2956    15 GLNYLLnGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110
                  ....*....|....*....|....*....|..
gi 568967333 1693 LLPVLRQFVGsffkpgfEKYSNVDLFRYLLNI 1724
Cdd:COG2956    95 AEELLEKLLE-------LDPDDAEALRLLAEI 119
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1351-1521 1.47e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.04  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG2956    96 EELLEKLLELDPDDAEALRLLAEIYEQEGD------WEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1431 AVEYAPDYQSFWTFL-HLEstFEEKDYvcERMVEFLMGAAKREISDilsfqlLEALLFRVQLHIFTGRCQSALAVLQNAL 1509
Cdd:COG2956   170 ALKLDPDCARALLLLaELY--LEQGDY--EEAIAALERALEQDPDY------LPALPRLAELYEKLGDPEEALELLRKAL 239

                         170
                  ....*....|..
gi 568967333 1510 KLANDAIVAEYL 1521
Cdd:COG2956   240 ELDPSDDLLLAL 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1610-1680 2.35e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 2.35e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568967333 1610 TNMIALHQL------LERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHL 1680
Cdd:COG4783    36 DNPEAFALLgeillqLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRL 112
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1609-1680 2.49e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 2.49e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568967333 1609 YTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHL 1680
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 827-1001 3.52e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  827 TKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMFLKKLQEQIHRVQQR 906
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  907 VTIKKaltlkygEELARAKAVASKeLGKRKLEQDRLGPN------KMMRLDNSpISSPRKHSAELIAMEKRRLQKLEYEY 980
Cdd:COG4942    99 LEAQK-------EELAELLRALYR-LGRQPPLALLLSPEdfldavRRLQYLKY-LAPARREQAEELRADLAELAALRAEL 169

                         170       180
                  ....*....|....*....|.
gi 568967333  981 ALKIQKLKEARALKAKEQQNL 1001
Cdd:COG4942   170 EAERAELEALLAELEEERAAL 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 738-1010 3.77e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 3.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   738 LESMIKEARRTAEQASKpkvppKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEM 817
Cdd:TIGR02168  710 LEEELEQLRKELEELSR-----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   818 --------DGIGRIAMVTKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSAN 889
Cdd:TIGR02168  785 eeleaqieQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   890 RMFLKKLQEQIHRVQQRVtikkaltlkygEELARAKAVASKELGKRKLEQDRLGpNKMMRLDNSpisspRKHSAELIAME 969
Cdd:TIGR02168  865 EELIEELESELEALLNER-----------ASLEEALALLRSELEELSEELRELE-SKRSELRRE-----LEELREKLAQL 927

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 568967333   970 KRRLQKLEYEYALKIQKLKEARALKAKEQQNLVPVVEEEPE 1010
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1351-1536 4.00e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 4.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG0457    62 LADYEQALELDPDDAEALNNLGLALQALGR------YEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1431 AVEYAPDYQSFWT----FLHLESTFEEKDYVCERMVEFLMGAAKREISDILSFQLLEALLFRVQLHIFTGRCQSALAVLQ 1506
Cdd:COG0457   136 ALELDPDDADALYnlgiALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILT 215

                         170       180       190
                  ....*....|....*....|....*....|
gi 568967333 1507 NALKLANDAIVAEYLKTDDRCLAWLAYIHL 1536
Cdd:COG0457   216 LAALAELLLLALALLLALRLAALALYQYRA 245
PTZ00121 PTZ00121
MAEBL; Provisional
 744-1097 7.27e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 7.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  744 EARRTAEQASKPKVPPKseKENDPLRTPEA----LPEEKKMEYRLLKEEIANREKQRLIKSDQLKTSssspANSDVEMDG 819
Cdd:PTZ00121 1388 EEKKKADEAKKKAEEDK--KKADELKKAAAakkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK----AEEAKKAEE 1461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  820 IGRIAMVTKQVADAEAKLKKHKilliKDESVLKNLvlQEAKKK--ESVRNAEAKitKLTEQLQAAEKILSANRmfLKKLQ 897
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAK----KADEAKKKA--EEAKKKadEAKKAAEAK--KKADEAKKAEEAKKADE--AKKAE 1531

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  898 E--QIHRVQQRVTIKKALTLKYGEELARAKAVASKElGKRKLEQDRLGPNK----MMRLDNSPISSPRKHSAELIAMEKR 971
Cdd:PTZ00121 1532 EakKADEAKKAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEEDKNMALRkaeeAKKAEEARIEEVMKLYEEEKKMKAE 1610

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  972 RLQKLEyEYALKIQKLKEARALKAKEQQNLVPVVEEEPEfsvpqpslhdltQDKLTLDTEENDVDDEVLSGASRERRRSF 1051
Cdd:PTZ00121 1611 EAKKAE-EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK------------AEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 568967333 1052 LESNSFTKPNLKHTDTPNKECINKLSKSTVEKPELFLGLKIGELQK 1097
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723
PTZ00121 PTZ00121
MAEBL; Provisional
 743-1080 7.84e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 7.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  743 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRliKSDQLKTSSSSPANSDVEMDGIGR 822
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK--KADELKKAEELKKAEEKKKAEEAK 1570

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  823 IAMVTKQVADAEAKLKKhKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKlTEQLQAAEKILSANRMFLKKLQEQihr 902
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAK-KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK-AEELKKAEEEKKKVEQLKKKEAEE--- 1645

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  903 vqqrvtIKKALTLKYGEELARAKavasKELGKRKLEQDRLGPNKMMRLDNSpisspRKHSAELIAMEKRRLQKLEYEYAL 982
Cdd:PTZ00121 1646 ------KKKAEELKKAEEENKIK----AAEEAKKAEEDKKKAEEAKKAEED-----EKKAAEALKKEAEEAKKAEELKKK 1710

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  983 KIQKLKEARALKAKEQQNLVPVVEEEPEFSVPQPSLHDLTQDKltldtEENDVDDEVLSGASRERRRSFLESNSFTKPNL 1062
Cdd:PTZ00121 1711 EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDE-----EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785

                         330
                  ....*....|....*...
gi 568967333 1063 KHTDTPNKECINKLSKST 1080
Cdd:PTZ00121 1786 DEEDEKRRMEVDKKIKDI 1803
zf-C3H1 pfam10650
Putative zinc-finger domain; This domain is conserved in fungi and might be a zinc-finger ...
 1189-1208 9.33e-06

Putative zinc-finger domain; This domain is conserved in fungi and might be a zinc-finger domain as it contains three conserved Cs and an H in the C-x8-C-x5-C-x3-H conformation typical of a zinc-finger.


Pssm-ID: 431418  Cd Length: 22  Bit Score: 43.72  E-value: 9.33e-06
                           10        20
                   ....*....|....*....|.
gi 568967333  1189 FCRFDLTG-TCNDDDCQWQHV 1208
Cdd:pfam10650    1 LCPYELAGgVCNDPSCEFQHF 21
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1351-1438 1.41e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.72  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG4783    58 IVLLHEALELDPDEPEARLNLGLALLKAGD------YDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEK 131


                  ....*...
gi 568967333 1431 AVEYAPDY 1438
Cdd:COG4783   132 ALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1613-1701 2.63e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 2.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1613 IALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCKFFILQDGGDK 1692
Cdd:COG3914    85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164


                  ....*....
gi 568967333 1693 LLPVLRQFV 1701
Cdd:COG3914   165 AIAALRRAL 173
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1351-1442 2.83e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 2.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG3914    98 LALYRRALALNPDNAEALFNLGNLLLALGR------LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRR 171

                          90
                  ....*....|..
gi 568967333 1431 AVEYAPDYQSFW 1442
Cdd:COG3914   172 ALELDPDNAEAL 183
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1351-1445 2.85e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG4783    24 EALLEKALELDPDNPEAFALLGEILLQLGD------LDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEK 97

                          90
                  ....*....|....*
gi 568967333 1431 AVEYAPDYQSFWTFL 1445
Cdd:COG4783    98 ALKLDPEHPEAYLRL 112
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 833-1049 3.33e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 3.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  833 AEAKLKKHKILLIKDESVLKNLVLQEAKKKEsvrnAEAKITKLTEQLQAAEKILSANRMFLKKLQEQIHRVQQRVTIKKA 912
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEE----LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  913 LTLKYGEELARAKAvASKELGKRKLEQDRLGPNKMMRLDNspissprkHSAELIAMEKrRLQKLEYEYALKIQKLKEARA 992
Cdd:COG1196   296 ELARLEQDIARLEE-RRRELEERLEELEEELAELEEELEE--------LEEELEELEE-ELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568967333  993 LKAKEQQNLVPVVEEepefsvpqpsLHDLTQDKLTLDTEENDVDDEVLSGASRERRR 1049
Cdd:COG1196   366 ALLEAEAELAEAEEE----------LEELAEELLEALRAAAELAAQLEELEEAEEAL 412
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1351-1538 3.36e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.69  E-value: 3.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG0457    28 IEDYEKALELDPDDAEALYNLGLAYLRLGR------YEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1431 AVEYAPDYQSFWTFLHLeSTFEEKDYvcERMVEFLMGAAKREISDIlsfqllEALLFRVQLHIFTGRCQSALAVLQNALK 1510
Cdd:COG0457   102 ALELDPDDAEALYNLGL-ALLELGRY--DEAIEAYERALELDPDDA------DALYNLGIALEKLGRYEEALELLEKLEA 172

                         170       180
                  ....*....|....*....|....*...
gi 568967333 1511 LANDAIVAEYLKTDDRCLAWLAYIHLIE 1538
Cdd:COG0457   173 AALAALLAAALGEAALALAAAEVLLALL 200
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1608-1671 3.53e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.11  E-value: 3.53e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568967333 1608 LYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNP 1671
Cdd:COG5010    90 LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 737-1035 6.15e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.97  E-value: 6.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   737 GLESMIKEARRTAEQaSKPKVPPKSEKENDPLRTPEALPEEKKMeyrLLKEEIANREKQRLIKSDqLKTSSSSPANSDVE 816
Cdd:pfam07888   77 ELESRVAELKEELRQ-SREKHEELEEKYKELSASSEELSEEKDA---LLAQRAAHEARIRELEED-IKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   817 MDGIG-RIAMVTKQVADAEAKLKKHKILLIKDESVLKNLV--LQEAKKKESVRNAEA-----KITKLTEQLQAAEKILSA 888
Cdd:pfam07888  152 LERMKeRAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSkeFQELRNSLAQRDTQVlqlqdTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   889 NRMFLKKL---QEQIHRVQQRVTIkkaltlkYGEELAraKAVASKELGKRKLEQDRLGPNKM----------MRLDNSPI 955
Cdd:pfam07888  232 NEALLEELrslQERLNASERKVEG-------LGEELS--SMAAQRDRTQAELHQARLQAAQLtlqladaslaLREGRARW 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   956 SSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAK--------EQQNLVPVVEEEPEFSVPQPSLHDLTQDKLT 1027
Cdd:pfam07888  303 AQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKlevelgreKDCNRVQLSESRRELQELKASLRVAQKEKEQ 382


                   ....*...
gi 568967333  1028 LDTEENDV 1035
Cdd:pfam07888  383 LQAEKQEL 390
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1351-1436 6.24e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.34  E-value: 6.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG5010    74 LALLEQALQLDPNNPELYYNLALLYSRSGD------KDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                  ....*.
gi 568967333 1431 AVEYAP 1436
Cdd:COG5010   148 ALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1615-1701 6.74e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 6.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1615 LHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRvWLTAFENNPQNAEIFYHLCKFFILQDGGDKLL 1694
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                  ....*..
gi 568967333 1695 PVLRQFV 1701
Cdd:COG3063    80 AYLERAL 86
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 201-998 9.47e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.66  E-value: 9.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   201 RKSSKSFGRSPSRKQNHSSKSENCAEETFEDLLLKYKQIQLELEciNKDEKLALSSKEETAQEdpKTLHLEDQTSTDNAS 280
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKK--LQEEELKLLAKEEEELK--SELLKLERRKVDDEE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   281 ITKDPSKEVAPEEKTQVKTFQAFELKpLRQKLTLPGDKNRVKRGKDGTRQLSLKSSTtdASQGLEDKEQNLTRRLSASDI 360
Cdd:pfam02463  315 KLKESEKEKKKAEKELKKEKEEIEEL-EKELKELEIKREAEEEEEEELEKLQEKLEQ--LEEELLAKKKLESERLSSAAK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   361 VSEKKLGEEEEELSelqlrllALQSASKKWQQKEQQVMKESKEKLTKTKTaQQKAKTSTKAHSAKKVSATAKQALRKQQT 440
Cdd:pfam02463  392 LKEEELELKSEEEK-------EAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLKD 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   441 KAWKKLQQQKEQERQKEEDQRKHAEEEERRKREEEIRKirdLSNQEEQYNRFMKLVGGKRRARSKSSDPDLRRSLEKQSD 520
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   521 SAGGIYQYDNYEEVAMDTDSETsspaAPSPVQPPFFPECSLGYFSSAPSVSLPPPAQVSSVPSLNQPYGEGLCVSLDPLP 600
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEE----RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   601 PLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREEllKSLASKRAFKpeETSSNSDPPSPPVLNNSQPLSRSNLSIVSIN 680
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG--VSLEEGLAEK--SEVKASLSELTKELLEIQELQEKAESELAKE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   681 TV-SQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGG-LESMIKEARRTAEQASKPKVP 758
Cdd:pfam02463  693 EIlRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEeEEKSRLKKEEKEEEKSELSLK 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   759 PKSEKENDPLRTPEALPEEKKMEYRLLKEEIANREKQRLIK------SDQLKTSSSSPANSDVEMDGIGRIAMVTKQVAD 832
Cdd:pfam02463  773 EKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEaelleeEQLLIEQEEKIKEEELEELALELKEEQKLEKLA 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   833 AEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMflkkLQEQIHRVQQRVTIKKA 912
Cdd:pfam02463  853 EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL----LEEKENEIEERIKEEAE 928

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   913 LTLKYGEELARAKAVASKElgKRKLEQDRLGPNKMMRLDNSPISSPRKHSAELIaMEKRRLQKLEYEYALKIQKLKEARA 992
Cdd:pfam02463  929 ILLKYEEEPEELLLEEADE--KEKEENNKEEEEERNKRLLLAKEELGKVNLMAI-EEFEEKEERYNKDELEKERLEEEKK 1005


                   ....*.
gi 568967333   993 LKAKEQ 998
Cdd:pfam02463 1006 KLIRAI 1011
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1609-1671 1.37e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 1.37e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568967333 1609 YTNMIALHQLLERYEEAVELcTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNP 1671
Cdd:COG3063    29 LNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1365-1514 2.18e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 2.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1365 VQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPDYQSFWTF 1444
Cdd:COG4783     4 AEALYALAQALLLAGD------YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLN 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1445 LhLESTFEEKDYvcERMVEFLMGAAKREISDILSFQLLEALLFRvqlhifTGRCQSALAVLQNALKLAND 1514
Cdd:COG4783    78 L-GLALLKAGDY--DEALALLEKALKLDPEHPEAYLRLARAYRA------LGRPDEAIAALEKALELDPD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1351-1437 2.52e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNvLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCET 1430
Cdd:COG3063    12 EEYYEKALELDPDNADALNNLGLLLLEQGR------YDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                  ....*..
gi 568967333 1431 AVEYAPD 1437
Cdd:COG3063    85 ALELDPS 91
PTZ00121 PTZ00121
MAEBL; Provisional
 744-1008 3.60e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 3.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  744 EARRTAEQASKPKVPPKSEKENdplRTPEALPEEKKMEYRLLKEEIANRekqrliKSDQLKTSSSSPANSDVEMDGIGRI 823
Cdd:PTZ00121 1333 AAKKKAEEAKKAAEAAKAEAEA---AADEAEAAEEKAEAAEKKKEEAKK------KADAAKKKAEEKKKADEAKKKAEED 1403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  824 AMVTKQVADAEAKLKKHKILLIKDESVLKnlvLQEAKKK-ESVRNAEAKITKLTEQLQAAEKILSANRMflKKLQEQIHR 902
Cdd:PTZ00121 1404 KKKADELKKAAAAKKKADEAKKKAEEKKK---ADEAKKKaEEAKKADEAKKKAEEAKKAEEAKKKAEEA--KKADEAKKK 1478

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  903 VQQRvtiKKALTLKYGEELARAKA--VASKELGKRKLEQDRLGPNKMMRLDNSPISSPRKHSAELIAMEKRRLQKL---- 976
Cdd:PTZ00121 1479 AEEA---KKADEAKKKAEEAKKKAdeAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELkkae 1555

                         250       260       270
                  ....*....|....*....|....*....|..
gi 568967333  977 EYEYALKIQKLKEARalKAKEQQNLVPVVEEE 1008
Cdd:PTZ00121 1556 ELKKAEEKKKAEEAK--KAEEDKNMALRKAEE 1585
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 1621-1671 3.70e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.93  E-value: 3.70e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568967333 1621 RYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNP 1671
Cdd:cd24142    15 NFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1568-1675 3.88e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.30  E-value: 3.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1568 QAAQDVKTNPD-----LLLAV-------FEDAVKACTDETLTSGERIEVclplYTNMIALHQLLERYEEAVELCTSLLES 1635
Cdd:COG4235     5 RLRQALAANPNdaegwLLLGRaylrlgrYDEALAAYEKALRLDPDNADA----LLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 568967333 1636 CPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAE 1675
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1354-1682 4.48e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 4.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1354 LEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVE 1433
Cdd:TIGR02917  556 LEKAAELNPQEIEPALALAQYYLGKGQ------LKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLA 629

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1434 YAPD-----------YQSF------WTFLHLESTFEEKDYVCERMVEFLMGAAKREISDILSFQLLE------ALLFRV- 1489
Cdd:TIGR02917  630 LQPDsalalllladaYAVMknyakaITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQkqhpkaALGFELe 709

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1490 -QLHIFTGRCQSALAVLQNALKLANDAIVAEYL-----------KTDDRCLAWLAyihliefnslpsklyDPSNANPSRI 1557
Cdd:TIGR02917  710 gDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLhrallasgntaEAVKTLEAWLK---------------THPNDAVLRT 774

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  1558 VNTEPFVMPWQAAQDVKtnpdlllaVFEDAVKACTDetltsgerievclplytNMIALHQL----LERYE-EAVELCTSL 1632
Cdd:TIGR02917  775 ALAELYLAQKDYDKAIK--------HYQTVVKKAPD-----------------NAVVLNNLawlyLELKDpRALEYAERA 829

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 568967333  1633 LESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHLCK 1682
Cdd:TIGR02917  830 LKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 820-1082 5.20e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 5.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   820 IGRIAMVTKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILS---------ANR 890
Cdd:TIGR00618  299 IKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSireiscqqhTLT 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   891 MFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKElgkRKLEQDRLGPNKMMRLDNSPISSPRKHSAELIA--- 967
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAF---RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQcek 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   968 MEKRRLQKLEYEYALKIQKLK----------------EARALKAKEQQNLVPVVEEEPE--------FSVPQPSLHDLTQ 1023
Cdd:TIGR00618  456 LEKIHLQESAQSLKEREQQLQtkeqihlqetrkkavvLARLLELQEEPCPLCGSCIHPNparqdidnPGPLTRRMQRGEQ 535

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568967333  1024 DKLTLDTEENDVDDEVLSgaSRERRRSF-----LESNSFTKpnLKHTDTPNKECINKLSKSTVE 1082
Cdd:TIGR00618  536 TYAQLETSEEDVYHQLTS--ERKQRASLkeqmqEIQQSFSI--LTQCDNRSKEDIPNLQNITVR 595
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1361-1520 5.56e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 5.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1361 NPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPDYqs 1440
Cdd:COG0457     4 DPDDAEAYNNLGLAYRRLGR------YEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333 1441 FWTFLHLESTFEE-KDYvcERMVEFLMGAAKREISDIlsfqllEALLFRVQLHIFTGRCQSALAVLQNALKLANDAIVAE 1519
Cdd:COG0457    76 AEALNNLGLALQAlGRY--EEALEDYDKALELDPDDA------EALYNLGLALLELGRYDEAIEAYERALELDPDDADAL 147


                  .
gi 568967333 1520 Y 1520
Cdd:COG0457   148 Y 148
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 743-1070 5.62e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 5.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   743 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKMEYRLLKEEIA------NREKQRLIKSDQLKTSSSSPANSDVE 816
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKllakeeEELKSELLKLERRKVDDEEKLKESEK 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   817 MDG--IGRIAMVTKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSANRMF-- 892
Cdd:pfam02463  322 EKKkaEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELks 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   893 --LKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKELGKRKLEQDRLGPNKMMRLDNSPISSPRKHSAELIAMEK 970
Cdd:pfam02463  402 eeEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   971 RRLQKLEyeyALKIQKLKEARalkAKEQQNLVPVVEEEPEFSVPQPSLHDLTQDKLTlDTEENDVDDEVLSGASRERRRS 1050
Cdd:pfam02463  482 LQEQLEL---LLSRQKLEERS---QKESKARSGLKVLLALIKDGVGGRIISAHGRLG-DLGVAVENYKVAISTAVIVEVS 554

                          330       340
                   ....*....|....*....|
gi 568967333  1051 FLESNSFTKPNLKHTDTPNK 1070
Cdd:pfam02463  555 ATADEVEERQKLVRALTELP 574
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 777-999 1.08e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  777 EKKMEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEmdgigrIAMVTKQVADAEAKLKKHKILLIKDESVLKNLVL 856
Cdd:COG1196   210 EKAERYRELKEELKELEAELLLLKLRELEAELEELEAELE------ELEAELEELEAELAELEAELEELRLELEELELEL 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  857 QEAKKKEsvRNAEAKITKLTEQLQAAEKILSANRMFLKKLQEQIHRVQQRVtikkaltLKYGEELARAKAVASKELGKRK 936
Cdd:COG1196   284 EEAQAEE--YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL-------EELEEELEELEEELEEAEEELE 354

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568967333  937 LEQDRLgpnkmmrldnspisspRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQ 999
Cdd:COG1196   355 EAEAEL----------------AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401
PRK12704 PRK12704
phosphodiesterase; Provisional
 739-926 2.39e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  739 ESMIKEARRTAEQASKpkvppksekendplrtpEALPEEKKmEYRLLKEEIANREKQRLIKSDQLKtsssspansdvemd 818
Cdd:PRK12704   41 KRILEEAKKEAEAIKK-----------------EALLEAKE-EIHKLRNEFEKELRERRNELQKLE-------------- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333  819 gigriamvtKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKL-TEQLQAAEKI--LS---ANRMF 892
Cdd:PRK12704   89 ---------KRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELiEEQLQELERIsgLTaeeAKEIL 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 568967333  893 LKKLQEQIhRVQQRVTIKKAltlkygEELARAKA 926
Cdd:PRK12704  160 LEKVEEEA-RHEAAVLIKEI------EEEAKEEA 186
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1615-1680 2.60e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 2.60e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967333 1615 LHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEIFYHL 1680
Cdd:COG4235    26 AYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL 91
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 835-993 4.18e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   835 AKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTE-QLQAAEKILSANRMFLKKLQEQIHRVQQRVT----- 908
Cdd:TIGR00618  559 ASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEkLSEAEDMLACEQHALLRKLQPEQDLQDVRLHlqqcs 638

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   909 --IKKALTLKYGEELA------RAKAVASKELGKRKLEQDRLGPNKM--------------------MRLDNSPISSPRK 960
Cdd:TIGR00618  639 qeLALKLTALHALQLTltqervREHALSIRVLPKELLASRQLALQKMqsekeqltywkemlaqcqtlLRELETHIEEYDR 718

                          170       180       190
                   ....*....|....*....|....*....|...
gi 568967333   961 HSAELIAMEKRRLQKLEYEYALKIQKLKEARAL 993
Cdd:TIGR00618  719 EFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1608-1673 4.95e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 4.95e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967333 1608 LYTNMIALHQLLERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQN 1673
Cdd:COG4783    74 ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
1608-1661 6.67e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.37  E-value: 6.67e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568967333  1608 LYTNMIALHQLLERYEEAVELCTSLLESC--------PTNCQLLETLAALYLKTDRYDKARR 1661
Cdd:pfam13424    5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALE 66
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 776-1028 6.93e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 6.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   776 EEKKMEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEMDGIGRiamvTKQVADAEAKLKKHKILLIKDEsvLKNLV 855
Cdd:TIGR02168  284 EELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES----KLDELAEELAELEEKLEELKEE--LESLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   856 LQEAKKKESVRNAEAKITKLTEQLQAAekilsANRMFLKKLQEQIHRVQQRVtikkaltlkYGEELARAKAVASKELGKR 935
Cdd:TIGR02168  358 AELEELEAELEELESRLEELEEQLETL-----RSKVAQLELQIASLNNEIER---------LEARLERLEDRRERLQQEI 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967333   936 KLEQDRLGPNKMMRLdnspissprkhsAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNLVPVVEEEPEFSVPQ 1015
Cdd:TIGR02168  424 EELLKKLEEAELKEL------------QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250
                   ....*....|...
gi 568967333  1016 PSLHDLTQDKLTL 1028
Cdd:TIGR02168  492 DSLERLQENLEGF 504
TPR_19 pfam14559
Tetratricopeptide repeat;
1620-1676 7.39e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.79  E-value: 7.39e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 568967333  1620 ERYEEAVELCTSLLESCPTNCQLLETLAALYLKTDRYDKARRVWLTAFENNPQNAEI 1676
Cdd:pfam14559    2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRY 58
TPR_19 pfam14559
Tetratricopeptide repeat;
1351-1408 7.99e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.79  E-value: 7.99e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568967333  1351 IANLEASVLENPSHVQLWLKLAYKYLNQNEglcsesLDSALNVLARALENNKDNPEIW 1408
Cdd:pfam14559    8 LELLEQALAEDPDNAEARLGLAEALLALGR------LDEAEALLAALPAADPDDPRYA 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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