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Conserved domains on  [gi|568961728|ref|XP_006511350|]
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GPI mannosyltransferase 3 isoform X3 [Mus musculus]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 51-254 5.38e-61

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member pfam03901:

Pssm-ID: 473917  Cd Length: 414  Bit Score: 202.59  E-value: 5.38e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728   51 YLVLFTIALRILNCFLVQTSfVPDEYWQSLEVAHRMVFSYGYLTWEWTER--LRGYTYPLIFASIYKVLHLLGKDSVQFL 128
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWSPKygIRSYLYPLLFALPYYLLARLFGDSKYLV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728  129 IWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSV--- 205
Cdd:pfam03901  80 FYAPRLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTSVsny 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568961728  206 -NSVKYSLLVALACVVRPTALIPWVPLLFRHFYQE-QRKLHLTLHHFLPVG 254
Cdd:pfam03901 160 kYLKAVLLIAALAILGRPTSALLWLPLVLYLLLRLrGKRLKLFLFLAISLG 210
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 51-254 5.38e-61

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 202.59  E-value: 5.38e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728   51 YLVLFTIALRILNCFLVQTSfVPDEYWQSLEVAHRMVFSYGYLTWEWTER--LRGYTYPLIFASIYKVLHLLGKDSVQFL 128
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWSPKygIRSYLYPLLFALPYYLLARLFGDSKYLV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728  129 IWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSV--- 205
Cdd:pfam03901  80 FYAPRLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTSVsny 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568961728  206 -NSVKYSLLVALACVVRPTALIPWVPLLFRHFYQE-QRKLHLTLHHFLPVG 254
Cdd:pfam03901 160 kYLKAVLLIAALAILGRPTSALLWLPLVLYLLLRLrGKRLKLFLFLAISLG 210
PLN02816 PLN02816
mannosyltransferase
 39-254 5.36e-51

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 179.46  E-value: 5.36e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728  39 RSPRRgllgentyLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLH 118
Cdd:PLN02816  36 GSPRR--------IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQ 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728 119 LLGKDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYP 198
Cdd:PLN02816 108 VTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWP 187

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728 199 LEGSRSVN---SVKYSLLV-ALACVVRPTALIPWVPLLFRHFYQEQRKLHLTLHHFLPVG 254
Cdd:PLN02816 188 CIRDSSIDypvNRKWGLVIaALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIG 247
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 51-254 5.38e-61

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 202.59  E-value: 5.38e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728   51 YLVLFTIALRILNCFLVQTSfVPDEYWQSLEVAHRMVFSYGYLTWEWTER--LRGYTYPLIFASIYKVLHLLGKDSVQFL 128
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWSPKygIRSYLYPLLFALPYYLLARLFGDSKYLV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728  129 IWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSV--- 205
Cdd:pfam03901  80 FYAPRLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTSVsny 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568961728  206 -NSVKYSLLVALACVVRPTALIPWVPLLFRHFYQE-QRKLHLTLHHFLPVG 254
Cdd:pfam03901 160 kYLKAVLLIAALAILGRPTSALLWLPLVLYLLLRLrGKRLKLFLFLAISLG 210
PLN02816 PLN02816
mannosyltransferase
 39-254 5.36e-51

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 179.46  E-value: 5.36e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728  39 RSPRRgllgentyLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLH 118
Cdd:PLN02816  36 GSPRR--------IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQ 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728 119 LLGKDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYP 198
Cdd:PLN02816 108 VTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWP 187

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961728 199 LEGSRSVN---SVKYSLLV-ALACVVRPTALIPWVPLLFRHFYQEQRKLHLTLHHFLPVG 254
Cdd:PLN02816 188 CIRDSSIDypvNRKWGLVIaALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIG 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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