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Conserved domains on  [gi|568958628|ref|XP_006509964|]
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alpha-1,2-mannosyltransferase ALG9 isoform X1 [Mus musculus]

Protein Classification

Glyco_transf_22 domain-containing protein( domain architecture ID 10511211)

Glyco_transf_22 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
60-482 9.57e-141

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


:

Pssm-ID: 281842  Cd Length: 414  Bit Score: 413.68  E-value: 9.57e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628   60 TAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVF 139
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTSDPDEHFQSWEPLHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGDSKYLVF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  140 YFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTGW--------YMDK 211
Cdd:pfam03901  81 YAPRLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLleygntsvSNYK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  212 TPIAVLGVAAGAILGWPFSAALGLPIAFDLL--ARKHRWKSFL--LWSLVALALFLVP--VVVIDSYYYGKLVVAPLNIV 285
Cdd:pfam03901 161 YLKAVLLIAALAILGRPTSALLWLPLVLYLLlrLRGKRLKLFLflAISLGLLVALLVLgaVILIDSYFYGRFVFTPLNFL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  286 LYNVFtSHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQrfhvqnlghpYWLTLAPMYIWFIIFFIQP 365
Cdd:pfam03901 241 KYNVL-SNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVSR----------LSQLLAPILIWLFIYSLQP 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  366 HKEERFLFPVYPLICLCGAVALSALQkcyhfvfQRYRLEHYTVTSNWLalgtvFLFGLLSFSRSVALFRGYHGPLDLYPE 445
Cdd:pfam03901 310 HKEERFLYPVYPLILLSAAIALTRLS-------RRSWKVRKKLSLLFL-----LLFFNVSLARLFGLVHQYGAPLAVYDV 377
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 568958628  446 FYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLP 482
Cdd:pfam03901 378 MSFLNETPRENRNPAGPPVNVCIGMECYSTPSSFFLH 414
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
60-482 9.57e-141

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 413.68  E-value: 9.57e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628   60 TAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVF 139
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTSDPDEHFQSWEPLHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGDSKYLVF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  140 YFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTGW--------YMDK 211
Cdd:pfam03901  81 YAPRLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLleygntsvSNYK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  212 TPIAVLGVAAGAILGWPFSAALGLPIAFDLL--ARKHRWKSFL--LWSLVALALFLVP--VVVIDSYYYGKLVVAPLNIV 285
Cdd:pfam03901 161 YLKAVLLIAALAILGRPTSALLWLPLVLYLLlrLRGKRLKLFLflAISLGLLVALLVLgaVILIDSYFYGRFVFTPLNFL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  286 LYNVFtSHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQrfhvqnlghpYWLTLAPMYIWFIIFFIQP 365
Cdd:pfam03901 241 KYNVL-SNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVSR----------LSQLLAPILIWLFIYSLQP 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  366 HKEERFLFPVYPLICLCGAVALSALQkcyhfvfQRYRLEHYTVTSNWLalgtvFLFGLLSFSRSVALFRGYHGPLDLYPE 445
Cdd:pfam03901 310 HKEERFLYPVYPLILLSAAIALTRLS-------RRSWKVRKKLSLLFL-----LLFFNVSLARLFGLVHQYGAPLAVYDV 377
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 568958628  446 FYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLP 482
Cdd:pfam03901 378 MSFLNETPRENRNPAGPPVNVCIGMECYSTPSSFFLH 414
PLN02816 PLN02816
mannosyltransferase
64-391 2.76e-16

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 82.00  E-value: 2.76e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  64 CLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSpvYAIRSYayllLHAWPAAFHARILQTNKILVFYFL- 142
Cdd:PLN02816  45 CLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMi 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 143 ---RCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLaFLVLSTGM--FCSSSAFlpsSFCMYTTLIAMTGWYMD------- 210
Cdd:PLN02816 119 kapRLMQSIFSAIGDLYLYKLSDALYGGNVATWSL-FCQMANWFifFCLNRTF---SNCLETVLTIMGLYYWPcirdssi 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 211 KTPIA---VLGVAAGAILGWPFSAALGLPIA-FDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVL 286
Cdd:PLN02816 195 DYPVNrkwGLVIAALACAIRPTSAVIWLYVGmLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLK 274
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 287 YNvFTSHGPDLYGTEPWYFYLINGFLnfnvafalallvlpltfLMEYLLQRFHVQNLGHPYWLTLAPMYIWFI-IFFIQP 365
Cdd:PLN02816 275 FN-FLSSGGDYYGTHPWHWYFTQGFL-----------------VMLFTFTPFSIAGIIKSKNQKLSALILWVLaIYSILG 336
                        330       340
                 ....*....|....*....|....*.
gi 568958628 366 HKEERFLFPVYPLICLCGAVALSALQ 391
Cdd:PLN02816 337 HKEFRFVLPVLPIALIFSGYAFAQME 362
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
60-482 9.57e-141

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 413.68  E-value: 9.57e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628   60 TAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVF 139
Cdd:pfam03901   1 WIFLLLLALRLLLALLVQTSDPDEHFQSWEPLHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGDSKYLVF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  140 YFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTGW--------YMDK 211
Cdd:pfam03901  81 YAPRLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLleygntsvSNYK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  212 TPIAVLGVAAGAILGWPFSAALGLPIAFDLL--ARKHRWKSFL--LWSLVALALFLVP--VVVIDSYYYGKLVVAPLNIV 285
Cdd:pfam03901 161 YLKAVLLIAALAILGRPTSALLWLPLVLYLLlrLRGKRLKLFLflAISLGLLVALLVLgaVILIDSYFYGRFVFTPLNFL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  286 LYNVFtSHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQrfhvqnlghpYWLTLAPMYIWFIIFFIQP 365
Cdd:pfam03901 241 KYNVL-SNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVSR----------LSQLLAPILIWLFIYSLQP 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  366 HKEERFLFPVYPLICLCGAVALSALQkcyhfvfQRYRLEHYTVTSNWLalgtvFLFGLLSFSRSVALFRGYHGPLDLYPE 445
Cdd:pfam03901 310 HKEERFLYPVYPLILLSAAIALTRLS-------RRSWKVRKKLSLLFL-----LLFFNVSLARLFGLVHQYGAPLAVYDV 377
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 568958628  446 FYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLP 482
Cdd:pfam03901 378 MSFLNETPRENRNPAGPPVNVCIGMECYSTPSSFFLH 414
PLN02816 PLN02816
mannosyltransferase
64-391 2.76e-16

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 82.00  E-value: 2.76e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628  64 CLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSpvYAIRSYayllLHAWPAAFHARILQTNKILVFYFL- 142
Cdd:PLN02816  45 CLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMi 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 143 ---RCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLaFLVLSTGM--FCSSSAFlpsSFCMYTTLIAMTGWYMD------- 210
Cdd:PLN02816 119 kapRLMQSIFSAIGDLYLYKLSDALYGGNVATWSL-FCQMANWFifFCLNRTF---SNCLETVLTIMGLYYWPcirdssi 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 211 KTPIA---VLGVAAGAILGWPFSAALGLPIA-FDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVL 286
Cdd:PLN02816 195 DYPVNrkwGLVIAALACAIRPTSAVIWLYVGmLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLK 274
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 287 YNvFTSHGPDLYGTEPWYFYLINGFLnfnvafalallvlpltfLMEYLLQRFHVQNLGHPYWLTLAPMYIWFI-IFFIQP 365
Cdd:PLN02816 275 FN-FLSSGGDYYGTHPWHWYFTQGFL-----------------VMLFTFTPFSIAGIIKSKNQKLSALILWVLaIYSILG 336
                        330       340
                 ....*....|....*....|....*.
gi 568958628 366 HKEERFLFPVYPLICLCGAVALSALQ 391
Cdd:PLN02816 337 HKEFRFVLPVLPIALIFSGYAFAQME 362
PRK07668 PRK07668
hypothetical protein; Validated
224-370 3.61e-03

hypothetical protein; Validated


Pssm-ID: 181074  Cd Length: 254  Bit Score: 39.60  E-value: 3.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 224 ILGWPFS---AALGLPIAFDLLARKHRW--KSFLLWSLVALALFLVPVVVIdsyyygklvvaplnivLYNVFtshgpdlY 298
Cdd:PRK07668 110 LIGYPISlilTIIGLIFLLRMASFKSKLteKWFLIIYLVILIPMLLIVAIM----------------FLNKW-------Y 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568958628 299 GTEPWYF-----YLINGF-------LNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPH 366
Cdd:PRK07668 167 GTPMLQFtqmqsYILAGLiflitviINIYFLGWFGLLYLIIPLSIMFLFKYFNSEDVVPMIFQIIILYGSLYVLMFIEIK 246

                 ....
gi 568958628 367 KEER 370
Cdd:PRK07668 247 REKN 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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