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Conserved domains on  [gi|568943184|ref|XP_006506822|]
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protein KRBA1 isoform X3 [Mus musculus]

Protein Classification

PHA03247 and KRBA1 domain-containing protein( domain architecture ID 10633813)

PHA03247 and KRBA1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 250-293 2.17e-08

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


:

Pssm-ID: 464615  Cd Length: 44  Bit Score: 51.26  E-value: 2.17e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 568943184   250 GSMGTGTLPENSPLQGLINCLKEILVPRPQHRGTAPDLPPSLPG 293
Cdd:pfam15287    1 GPMAQGASPGSSPLQGLINCLKEILVPGPQHPQPATSLSPPPQP 44
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 424-467 8.99e-07

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


:

Pssm-ID: 464615  Cd Length: 44  Bit Score: 46.64  E-value: 8.99e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 568943184   424 GPMTLASRASSSPLEALEACLKGIPPGGSSPLQsLAISWSRSPQ 467
Cdd:pfam15287    1 GPMAQGASPGSSPLQGLINCLKEILVPGPQHPQ-PATSLSPPPQ 43
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 758-875 5.20e-04

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 44.30  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568943184  758 SAGRAEEKPH-PPRREDGAERTRQPGPvtnaegkgAAAGHPSPAPQLEEKPE-PKGTEDSRDLEPGHRPPSAaaRTQGKL 835
Cdd:PTZ00449  537 SKESDEPKEGgKPGETKEGEVGKKPGP--------AKEHKPSKIPTLSKKPEfPKDPKHPKDPEEPKKPKRP--RSAQRP 606

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 568943184  836 LSGDPPESPSKSPLPTTVLSKWSPTSLQPPCPCGRSLQQE 875
Cdd:PTZ00449  607 TRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPE 646
KRBA1 super family cl21135
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 546-577 5.44e-04

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


The actual alignment was detected with superfamily member pfam15287:

Pssm-ID: 464615  Cd Length: 44  Bit Score: 38.55  E-value: 5.44e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 568943184   546 GYLPGNSPLQGLENCLREIPIPRPQAAWPCSS 577
Cdd:pfam15287    6 GASPGSSPLQGLINCLKEILVPGPQHPQPATS 37
 
Name Accession Description Interval E-value
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 250-293 2.17e-08

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


Pssm-ID: 464615  Cd Length: 44  Bit Score: 51.26  E-value: 2.17e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 568943184   250 GSMGTGTLPENSPLQGLINCLKEILVPRPQHRGTAPDLPPSLPG 293
Cdd:pfam15287    1 GPMAQGASPGSSPLQGLINCLKEILVPGPQHPQPATSLSPPPQP 44
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 424-467 8.99e-07

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


Pssm-ID: 464615  Cd Length: 44  Bit Score: 46.64  E-value: 8.99e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 568943184   424 GPMTLASRASSSPLEALEACLKGIPPGGSSPLQsLAISWSRSPQ 467
Cdd:pfam15287    1 GPMAQGASPGSSPLQGLINCLKEILVPGPQHPQ-PATSLSPPPQ 43
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 758-875 5.20e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 44.30  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568943184  758 SAGRAEEKPH-PPRREDGAERTRQPGPvtnaegkgAAAGHPSPAPQLEEKPE-PKGTEDSRDLEPGHRPPSAaaRTQGKL 835
Cdd:PTZ00449  537 SKESDEPKEGgKPGETKEGEVGKKPGP--------AKEHKPSKIPTLSKKPEfPKDPKHPKDPEEPKKPKRP--RSAQRP 606

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 568943184  836 LSGDPPESPSKSPLPTTVLSKWSPTSLQPPCPCGRSLQQE 875
Cdd:PTZ00449  607 TRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPE 646
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 546-577 5.44e-04

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


Pssm-ID: 464615  Cd Length: 44  Bit Score: 38.55  E-value: 5.44e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 568943184   546 GYLPGNSPLQGLENCLREIPIPRPQAAWPCSS 577
Cdd:pfam15287    6 GASPGSSPLQGLINCLKEILVPGPQHPQPATS 37
 
Name Accession Description Interval E-value
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 250-293 2.17e-08

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


Pssm-ID: 464615  Cd Length: 44  Bit Score: 51.26  E-value: 2.17e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 568943184   250 GSMGTGTLPENSPLQGLINCLKEILVPRPQHRGTAPDLPPSLPG 293
Cdd:pfam15287    1 GPMAQGASPGSSPLQGLINCLKEILVPGPQHPQPATSLSPPPQP 44
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 424-467 8.99e-07

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


Pssm-ID: 464615  Cd Length: 44  Bit Score: 46.64  E-value: 8.99e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 568943184   424 GPMTLASRASSSPLEALEACLKGIPPGGSSPLQsLAISWSRSPQ 467
Cdd:pfam15287    1 GPMAQGASPGSSPLQGLINCLKEILVPGPQHPQ-PATSLSPPPQ 43
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 758-875 5.20e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 44.30  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568943184  758 SAGRAEEKPH-PPRREDGAERTRQPGPvtnaegkgAAAGHPSPAPQLEEKPE-PKGTEDSRDLEPGHRPPSAaaRTQGKL 835
Cdd:PTZ00449  537 SKESDEPKEGgKPGETKEGEVGKKPGP--------AKEHKPSKIPTLSKKPEfPKDPKHPKDPEEPKKPKRP--RSAQRP 606

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 568943184  836 LSGDPPESPSKSPLPTTVLSKWSPTSLQPPCPCGRSLQQE 875
Cdd:PTZ00449  607 TRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPE 646
KRBA1 pfam15287
KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is ...
 546-577 5.44e-04

KRBA1 family repeat; KRBA1 is a short repeating motif found in mammalian proteins. It is characterized by a highly conserved sequence of residues, SSPLxxLxxCLK. The function of the repeat, which can be present in up to seven copies, is unknown as is the function of the full length proteins.


Pssm-ID: 464615  Cd Length: 44  Bit Score: 38.55  E-value: 5.44e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 568943184   546 GYLPGNSPLQGLENCLREIPIPRPQAAWPCSS 577
Cdd:pfam15287    6 GASPGSSPLQGLINCLKEILVPGPQHPQPATS 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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