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Conserved domains on  [gi|568916562|ref|XP_006499356|]
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spermine oxidase isoform X12 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02568 super family cl33517
polyamine oxidase
 50-403 8.60e-46

polyamine oxidase


The actual alignment was detected with superfamily member PLN02568:

Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 165.39  E-value: 8.60e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  50 DVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGriSLYSKNGVAcyltNRGC 129
Cdd:PLN02568  35 ELTVVEGGDRIGGRINTSEFGGERIEMGATWIHGIGGSPVYKIAQEAGSLESDEPWECMDG--FPDRPKTVA----EGGF 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 130 RIPKDVVEEFSDLYNEVYNMTQ---------EFFRHGKPVNAESQ-------NSVGVFTREKVRNrIRDDPDDTEATKR- 192
Cdd:PLN02568 109 EVDPSIVESISTLFRGLMDDAQgkliepsevDEVDFVKLAAKAARvcesgggGSVGSFLRRGLDA-YWDSVSADEQIKGy 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 193 -------LKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIH 265
Cdd:PLN02568 188 ggwsrklLEEAIFTMHENTQRTYTSADDLSTLDLAAESEYRMFPGEEITIAKGYLSVIEALASVLPPGTIQLGRKVTRIE 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 266 W-----------------------------------DQASAHPRGP--------------------EIEPR--------- 281
Cdd:PLN02568 268 WqdepvklhfadgstmtadhvivtvslgvlkagigeDSGLFSPPLPdfktdaisrlgfgvvnklfvELSPRpdgspedva 347

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 282 GNPN----------------IP---------------------------------------------------------- 287
Cdd:PLN02568 348 KFPFlqmafhrsdsearhdkIPwwmrrtasicpihknssvllswfagkealeleklsdeeiirgvqttlssflkrrvagl 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 288 --------------------KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPytessktahRSSTEQQPGhl 347
Cdd:PLN02568 428 gsqshplcnggassndgsrwKFVKVLKSKWGTDPLFLGSYSYVAVGSSGDDLDRMAEPLP---------RISDHDQAG-- 496

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568916562 348 lpskCPeqsldpsrgsikPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 403
Cdd:PLN02568 497 ----GP------------PLQLLFAGEATHRTHYSTTHGAYFSGLREANRLLQHYK 536
 
Name Accession Description Interval E-value
PLN02568 PLN02568
polyamine oxidase
 50-403 8.60e-46

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 165.39  E-value: 8.60e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  50 DVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGriSLYSKNGVAcyltNRGC 129
Cdd:PLN02568  35 ELTVVEGGDRIGGRINTSEFGGERIEMGATWIHGIGGSPVYKIAQEAGSLESDEPWECMDG--FPDRPKTVA----EGGF 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 130 RIPKDVVEEFSDLYNEVYNMTQ---------EFFRHGKPVNAESQ-------NSVGVFTREKVRNrIRDDPDDTEATKR- 192
Cdd:PLN02568 109 EVDPSIVESISTLFRGLMDDAQgkliepsevDEVDFVKLAAKAARvcesgggGSVGSFLRRGLDA-YWDSVSADEQIKGy 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 193 -------LKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIH 265
Cdd:PLN02568 188 ggwsrklLEEAIFTMHENTQRTYTSADDLSTLDLAAESEYRMFPGEEITIAKGYLSVIEALASVLPPGTIQLGRKVTRIE 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 266 W-----------------------------------DQASAHPRGP--------------------EIEPR--------- 281
Cdd:PLN02568 268 WqdepvklhfadgstmtadhvivtvslgvlkagigeDSGLFSPPLPdfktdaisrlgfgvvnklfvELSPRpdgspedva 347

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 282 GNPN----------------IP---------------------------------------------------------- 287
Cdd:PLN02568 348 KFPFlqmafhrsdsearhdkIPwwmrrtasicpihknssvllswfagkealeleklsdeeiirgvqttlssflkrrvagl 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 288 --------------------KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPytessktahRSSTEQQPGhl 347
Cdd:PLN02568 428 gsqshplcnggassndgsrwKFVKVLKSKWGTDPLFLGSYSYVAVGSSGDDLDRMAEPLP---------RISDHDQAG-- 496

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568916562 348 lpskCPeqsldpsrgsikPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 403
Cdd:PLN02568 497 ----GP------------PLQLLFAGEATHRTHYSTTHGAYFSGLREANRLLQHYK 536
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 45-399 1.01e-23

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 102.57  E-value: 1.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562   45 EQGFtDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHgNPIYQLAEANGLLEETTDGERSVGRIslyskngvacYL 124
Cdd:pfam01593  12 RAGH-DVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHGAQ-PPLLALLKELGLEDRLVLPDPAPFYT----------VL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  125 TNRGCRIPKDvveeFSDLYNEVynmtQEFFRHGKPVNAES--QNSVGVFTREKVRNRIRDDPDDTEATKRLK-------- 194
Cdd:pfam01593  80 FAGGRRYPGD----FRRVPAGW----EGLLEFGRLLSIPEklRLGLAALASDALDEFDLDDFSLAESLLFLGrrgpgdve 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  195 ----LAMIQQYLKVESCeSSSHSIDEVSLSAFGEW-----TEIPGAHHIIPSGFM-RVVELLAEGIPPHVIQLGKPVRCI 264
Cdd:pfam01593 152 vwdrLIDPELFAALPFA-SGAFAGDPSELSAGLALpllwaLLGEGGSLLLPRGGLgALPDALAAQLLGGDVRLNTRVRSI 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  265 HW-------------------------------------------------------------------DQASAHPRG-- 275
Cdd:pfam01593 231 DRegdgvtvtltdgevieadavivtvplgvlkrilftpplppekarairnlgygpvnkvhlefdrkfwpDLGLLGLLSel 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  276 -------------PEIEPRG--------------------------------------NPNIPKPRRILRSAWGSNPYFR 304
Cdd:pfam01593 311 ltglgtafswltfPNRAPPGkgllllvyvgpgdrareleglsdeellqavlrdlrklfGEEAPEPLRVLVSDWHTDPWPR 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  305 GSYSYTQVGSSGADVEKLAKPLpytessktahrssteqQPGhllpskcpeqsldpsrgsikpmqVLFSGEATHRKYYSTT 384
Cdd:pfam01593 391 GSYSLPQYGPGHDDYRPLARTP----------------DPG-----------------------LFFAGEHTSTGYPGTV 431

                         490
                  ....*....|....*
gi 568916562  385 HGALLSGQREAARLI 399
Cdd:pfam01593 432 EGAIESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
45-400 6.90e-18

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 84.97  E-value: 6.90e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  45 EQGFtDVTVLEASSHIGGRVQSVRLGDT--TFELGATWIHGSHGNpIYQLAEANGLleETTDGERSVGRiSLYSKNGVAC 122
Cdd:COG1231   28 KAGL-DVTVLEARDRVGGRVWTLRFGDDglYAELGAMRIPPSHTN-LLALARELGL--PLEPFPNENGN-ALLYLGGKRV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 123 YLtnrgcRIPKDVVEEFSDLYNE-VYNMTQEFFRHGKPVNAESQNSVGVFtrekvrnrIRDDPDDTEAtkrlkLAMIQQY 201
Cdd:COG1231  103 RA-----GEIAADLRGVAELLAKlLRALAAALDPWAHPAAELDRESLAEW--------LRRNGASPSA-----RRLLGLL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 202 LKVESCESSshsiDEVSLSAF---GEWTEIPGAHHIIPSGFMRVVELLAEGIPPHvIQLGKPVRCIHWD----------- 267
Cdd:COG1231  165 GAGEYGADP----DELSLLDLlryAASAGGGAQQFRIVGGMDQLPRALAAELGDR-IRLGAPVTRIRQDgdgvtvttddg 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 268 -------------------------------QA-------------------------------------------SAHP 273
Cdd:COG1231  240 gtvradavivtvppsvlrriefdpplpaakrAAiqrlpygaaikvflqfdrpfweedglyggisltdlpirqtwypSNGP 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 274 RGP--------------EIEPRG----------------NPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLA 323
Cdd:COG1231  320 DGGagvllgyvggddarALAALSpeervaaaleqlarifGVYAAEPVDYVSTDWGRDPWSRGAYAAAPPGQLTAAGPALA 399

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568916562 324 KPlpytessktAHRssteqqpghllpskcpeqsldpsrgsikpmqVLFSGEATHRKYYSTTHGALLSGQREAARLIE 400
Cdd:COG1231  400 EP---------DGR-------------------------------IHFAGEHTSDEWPGWVEGALESGERAAAEILA 436
 
Name Accession Description Interval E-value
PLN02568 PLN02568
polyamine oxidase
 50-403 8.60e-46

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 165.39  E-value: 8.60e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  50 DVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGriSLYSKNGVAcyltNRGC 129
Cdd:PLN02568  35 ELTVVEGGDRIGGRINTSEFGGERIEMGATWIHGIGGSPVYKIAQEAGSLESDEPWECMDG--FPDRPKTVA----EGGF 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 130 RIPKDVVEEFSDLYNEVYNMTQ---------EFFRHGKPVNAESQ-------NSVGVFTREKVRNrIRDDPDDTEATKR- 192
Cdd:PLN02568 109 EVDPSIVESISTLFRGLMDDAQgkliepsevDEVDFVKLAAKAARvcesgggGSVGSFLRRGLDA-YWDSVSADEQIKGy 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 193 -------LKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIH 265
Cdd:PLN02568 188 ggwsrklLEEAIFTMHENTQRTYTSADDLSTLDLAAESEYRMFPGEEITIAKGYLSVIEALASVLPPGTIQLGRKVTRIE 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 266 W-----------------------------------DQASAHPRGP--------------------EIEPR--------- 281
Cdd:PLN02568 268 WqdepvklhfadgstmtadhvivtvslgvlkagigeDSGLFSPPLPdfktdaisrlgfgvvnklfvELSPRpdgspedva 347

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 282 GNPN----------------IP---------------------------------------------------------- 287
Cdd:PLN02568 348 KFPFlqmafhrsdsearhdkIPwwmrrtasicpihknssvllswfagkealeleklsdeeiirgvqttlssflkrrvagl 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 288 --------------------KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPytessktahRSSTEQQPGhl 347
Cdd:PLN02568 428 gsqshplcnggassndgsrwKFVKVLKSKWGTDPLFLGSYSYVAVGSSGDDLDRMAEPLP---------RISDHDQAG-- 496

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568916562 348 lpskCPeqsldpsrgsikPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 403
Cdd:PLN02568 497 ----GP------------PLQLLFAGEATHRTHYSTTHGAYFSGLREANRLLQHYK 536
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 45-399 1.01e-23

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 102.57  E-value: 1.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562   45 EQGFtDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHgNPIYQLAEANGLLEETTDGERSVGRIslyskngvacYL 124
Cdd:pfam01593  12 RAGH-DVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHGAQ-PPLLALLKELGLEDRLVLPDPAPFYT----------VL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  125 TNRGCRIPKDvveeFSDLYNEVynmtQEFFRHGKPVNAES--QNSVGVFTREKVRNRIRDDPDDTEATKRLK-------- 194
Cdd:pfam01593  80 FAGGRRYPGD----FRRVPAGW----EGLLEFGRLLSIPEklRLGLAALASDALDEFDLDDFSLAESLLFLGrrgpgdve 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  195 ----LAMIQQYLKVESCeSSSHSIDEVSLSAFGEW-----TEIPGAHHIIPSGFM-RVVELLAEGIPPHVIQLGKPVRCI 264
Cdd:pfam01593 152 vwdrLIDPELFAALPFA-SGAFAGDPSELSAGLALpllwaLLGEGGSLLLPRGGLgALPDALAAQLLGGDVRLNTRVRSI 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  265 HW-------------------------------------------------------------------DQASAHPRG-- 275
Cdd:pfam01593 231 DRegdgvtvtltdgevieadavivtvplgvlkrilftpplppekarairnlgygpvnkvhlefdrkfwpDLGLLGLLSel 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  276 -------------PEIEPRG--------------------------------------NPNIPKPRRILRSAWGSNPYFR 304
Cdd:pfam01593 311 ltglgtafswltfPNRAPPGkgllllvyvgpgdrareleglsdeellqavlrdlrklfGEEAPEPLRVLVSDWHTDPWPR 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  305 GSYSYTQVGSSGADVEKLAKPLpytessktahrssteqQPGhllpskcpeqsldpsrgsikpmqVLFSGEATHRKYYSTT 384
Cdd:pfam01593 391 GSYSLPQYGPGHDDYRPLARTP----------------DPG-----------------------LFFAGEHTSTGYPGTV 431

                         490
                  ....*....|....*
gi 568916562  385 HGALLSGQREAARLI 399
Cdd:pfam01593 432 EGAIESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
45-400 6.90e-18

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 84.97  E-value: 6.90e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  45 EQGFtDVTVLEASSHIGGRVQSVRLGDT--TFELGATWIHGSHGNpIYQLAEANGLleETTDGERSVGRiSLYSKNGVAC 122
Cdd:COG1231   28 KAGL-DVTVLEARDRVGGRVWTLRFGDDglYAELGAMRIPPSHTN-LLALARELGL--PLEPFPNENGN-ALLYLGGKRV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 123 YLtnrgcRIPKDVVEEFSDLYNE-VYNMTQEFFRHGKPVNAESQNSVGVFtrekvrnrIRDDPDDTEAtkrlkLAMIQQY 201
Cdd:COG1231  103 RA-----GEIAADLRGVAELLAKlLRALAAALDPWAHPAAELDRESLAEW--------LRRNGASPSA-----RRLLGLL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 202 LKVESCESSshsiDEVSLSAF---GEWTEIPGAHHIIPSGFMRVVELLAEGIPPHvIQLGKPVRCIHWD----------- 267
Cdd:COG1231  165 GAGEYGADP----DELSLLDLlryAASAGGGAQQFRIVGGMDQLPRALAAELGDR-IRLGAPVTRIRQDgdgvtvttddg 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 268 -------------------------------QA-------------------------------------------SAHP 273
Cdd:COG1231  240 gtvradavivtvppsvlrriefdpplpaakrAAiqrlpygaaikvflqfdrpfweedglyggisltdlpirqtwypSNGP 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 274 RGP--------------EIEPRG----------------NPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLA 323
Cdd:COG1231  320 DGGagvllgyvggddarALAALSpeervaaaleqlarifGVYAAEPVDYVSTDWGRDPWSRGAYAAAPPGQLTAAGPALA 399

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568916562 324 KPlpytessktAHRssteqqpghllpskcpeqsldpsrgsikpmqVLFSGEATHRKYYSTTHGALLSGQREAARLIE 400
Cdd:COG1231  400 EP---------DGR-------------------------------IHFAGEHTSDEWPGWVEGALESGERAAAEILA 436
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 272-403 1.45e-12

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 69.25  E-value: 1.45e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 272 HPRGPEIeprgnpniPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKplpytessktahrssteqqpghllpsk 351
Cdd:PLN02328 595 HPKGIVV--------PDPVQAVCTRWGKDCFTYGSYSYVAVGSSGDDYDILAE--------------------------- 639

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568916562 352 cpeqsldpsrgSIKPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 403
Cdd:PLN02328 640 -----------SVGDGRVFFAGEATNKQYPATMHGAFLSGMREAANILRVAR 680
PLN03000 PLN03000
amine oxidase
 279-398 6.56e-12

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 67.35  E-value: 6.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 279 EPRGnPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKplpytessktahrssteqqpghllpskcpeqsld 358
Cdd:PLN03000 539 EPQG-INVPDPLQTVCTRWGGDPFSLGSYSNVAVGASGDDYDILAE---------------------------------- 583

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 568916562 359 psrgSIKPMQVLFSGEATHRKYYSTTHGALLSGQREAARL 398
Cdd:PLN03000 584 ----SVGDGRLFFAGEATTRRYPATMHGAFVTGLREAANM 619
PLN02529 PLN02529
lysine-specific histone demethylase 1
 280-403 2.62e-11

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 65.30  E-value: 2.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 280 PRGnPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAkplpytessktahrsstEQQPGHLlpskcpeqsldp 359
Cdd:PLN02529 516 PKG-INVPDPIQTICTRWGSDPLSYGSYSHVRVQSSGSDYDILA-----------------ESVSGRL------------ 565

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 568916562 360 srgsikpmqvLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 403
Cdd:PLN02529 566 ----------FFAGEATTRQYPATMHGAFLSGLREASRILHVAR 599
PLN02676 PLN02676
polyamine oxidase
 25-400 4.60e-11

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 64.35  E-value: 4.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  25 PRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHG---NPIYQLAEANGLLEE 101
Cdd:PLN02676  27 PSVIIVGAGMSGISAAKTLSEAGIEDILILEATDRIGGRMRKANFAGVSVELGANWVEGVGGpesNPIWELANKLKLRTF 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 102 TTDGERSvgRISLYSKNGVACyltnrgcriPKDVVEEFSDLYNEVYNMTQEFfrhGKPVNAESQNSVGVFTREKVRNRIR 181
Cdd:PLN02676 107 YSDFDNL--SSNIYKQDGGLY---------PKKVVQKSMKVADASDEFGENL---SISLSAKKAVDISILTAQRLFGQVP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 182 DDPddteatkrLKLAMIQQYLKVESCE-----SSSHSIDEVSLSAFGEWTEIPGAhhiiPSGFMRVVELLAEG------- 249
Cdd:PLN02676 173 KTP--------LEMVIDYYNYDYEFAEpprvtSLKNTEPNPTFVDFGEDEYFVAD----PRGYESLVYYLAEQflstksg 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 250 -IPPHVIQLGKPVRCIHW---------DQASAH----------------------------------------------- 272
Cdd:PLN02676 241 kITDPRLKLNKVVREISYskngvtvktEDGSVYrakyvivsvslgvlqsdlikfkpplpdwkieaiyqfdmavytkiflk 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 273 ------PRGPEIE----------------------PRGN-----------------------------------PNIPKP 289
Cdd:PLN02676 321 fpykfwPSGPGTEfflyaherrgyypfwqhleneyPGSNvlfvtvtdeesrrieqqpdsetkaeimevlrkmfgPNIPEA 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 290 RRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLpytessktaHRssteqqpghllpskcpeqsldpsrgsikpmqV 369
Cdd:PLN02676 401 TDILVPRWWSNRFFKGSYSNWPIGVSRYEFDQIRAPV---------GR-------------------------------V 440

                        490       500       510
                 ....*....|....*....|....*....|.
gi 568916562 370 LFSGEATHRKYYSTTHGALLSGQREAARLIE 400
Cdd:PLN02676 441 YFTGEHTSEKYNGYVHGAYLAGIDTANDLLE 471
PLN02976 PLN02976
amine oxidase
 282-403 2.76e-10

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 62.58  E-value: 2.76e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  282 GNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLpytessktahrssteqqpghllpSKCpeqsldpsr 361
Cdd:PLN02976 1105 GEALVPDPVASVVTDWGRDPFSYGAYSYVAIGASGEDYDILGRPV-----------------------ENC--------- 1152

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 568916562  362 gsikpmqVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 403
Cdd:PLN02976 1153 -------LFFAGEATCKEHPDTVGGAMMSGLREAVRIIDILN 1187
PLN02268 PLN02268
probable polyamine oxidase
 25-261 5.20e-09

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 57.78  E-value: 5.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  25 PRVVVIGAGLAGLAAARALLEQGFtDVTVLEASSHIGGRVQSvrlgDTTF----ELGATWIHG-SHGNPIYQLAEANGLL 99
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASF-KVTLLESRDRIGGRVHT----DYSFgfpvDMGASWLHGvCNENPLAPLIGRLGLP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 100 EETTDGERSVgrisLYSKNGVACYLTNR-GCRIPKDVVEEFSDLYNEVYNMTqeffrhgkpvnaesqnsvgvftrEKVRN 178
Cdd:PLN02268  76 LYRTSGDNSV----LYDHDLESYALFDMdGNQVPQELVTKVGETFERILEET-----------------------EKVRD 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 179 RIRDDPDDTEATKR-------LKLA-----MIQQYL-KVESCESSshSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVEL 245
Cdd:PLN02268 129 EHEEDMSLLQAISIvlerhpeLRLEglaheVLQWYLcRMEGWFAA--DADTISLKSWDQEELLEGGHGLMVRGYDPVINT 206

                        250
                 ....*....|....*.
gi 568916562 246 LAEGIPphvIQLGKPV 261
Cdd:PLN02268 207 LAKGLD---IRLNHRV 219
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
45-94 8.19e-08

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 48.68  E-value: 8.19e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 568916562   45 EQGFtDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAE 94
Cdd:pfam13450  17 KRGF-RVLVLEKRDRLGGNAYSYRVPGYVFDYGAHIFHGSDEPNVRDLLD 65
PLN02268 PLN02268
probable polyamine oxidase
 51-391 9.26e-08

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 53.92  E-value: 9.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562  51 VTVLEASSHIGGRVQSvrlgDTTF----ELGATWIHG-SHGNPIYQLAEANGLLEETTDGERSVgrisLYSKNGVACYLT 125
Cdd:PLN02268  26 VTLLESRDRIGGRVHT----DYSFgfpvDMGASWLHGvCNENPLAPLIGRLGLPLYRTSGDNSV----LYDHDLESYALF 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 126 NR-GCRIPKDVVEEFSDLYNEVYNMTqeffrhgkpvnaesqnsvgvftrEKVRNRIRDDPDDTEATKR-------LKLA- 196
Cdd:PLN02268  98 DMdGNQVPQELVTKVGETFERILEET-----------------------EKVRDEHEEDMSLLQAISIvlerhpeLRLEg 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 197 ----MIQQYL-KVESCESSShsIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPphvIQLGKPVRCI------- 264
Cdd:PLN02268 155 laheVLQWYLcRMEGWFAAD--ADTISLKSWDQEELLEGGHGLMVRGYDPVINTLAKGLD---IRLNHRVTKIvrryngv 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 265 --------------------------------------------------------HWDQ-------------------- 268
Cdd:PLN02268 230 kvtvedgttfvadaaiiavplgvlkaniikfepelpewkeeaisdlgvgienkialHFDSvfwpnveflgvvaptsygcs 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916562 269 -------ASAHP---------RGPEIEPRGN---------------PNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGA 317
Cdd:PLN02268 310 yflnlhkATGHPvlvympagrLARDIEKLSDeaaanfamsqlkkmlPDATEPVQYLVSRWGSDPNSLGCYSYDLVGKPHD 389

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568916562 318 DVEKLAKPLPytessktahrssteqqpghllpskcpeqsldpsrgsikpmQVLFSGEATHRKYYSTTHGALLSG 391
Cdd:PLN02268 390 LYERLRAPVD----------------------------------------NLFFAGEATSSDFPGSVHGAYSTG 423
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 50-100 2.71e-05

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 46.00  E-value: 2.71e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568916562  50 DVTVLEASSHIGGRVQSVRLGDTTFELGATWI-HGSHGNPIYQLAEANGLLE 100
Cdd:COG1233   28 RVTVLEKNDTPGGRARTFERPGFRFDVGPSVLtMPGVLERLFRELGLEDYLE 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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