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Conserved domains on  [gi|565388484|ref|XP_006360007|]
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PREDICTED: conserved oligomeric Golgi complex subunit 5 [Solanum tuberosum]

Protein Classification

COG5 family protein( domain architecture ID 367728)

COG5 family protein similar to Arabidopsis thaliana conserved oligomeric Golgi complex subunit 5 (COG5) which is a component of the conserved oligomeric Golgi complex (COG), and is required for normal Golgi function

Gene Ontology:  GO:0015031
SCOP:  4004137

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5 super family cl46990
Golgi transport complex subunit 5; The COG complex, the peripheral membrane oligomeric protein ...
 80-193 1.34e-17

Golgi transport complex subunit 5; The COG complex, the peripheral membrane oligomeric protein complex involved in intra-Golgi protein trafficking, consists of eight subunits arranged in two lobes bridged by Cog1. Cog5 is in the smaller, B lobe, bound in with Cog6-8, and is itself bound to Cog1 as well as, strongly, to Cog7.


The actual alignment was detected with superfamily member pfam10392:

Pssm-ID: 192566  Cd Length: 132  Bit Score: 79.66  E-value: 1.34e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 565388484   80 TRFSSAALSS--------GSTASRIEKLQEGLRLLDHQLRHEVLTRHHDLLNQLTSLRAAESALSTLRSSVSSLQSSLRR 151
Cdd:pfam10392  11 KSFANALLLAtnnnddtpLDLSTPLKRLNYDIQELDRRIRTLITSNHLELLSHLSSIKSASSILSTLKSSLEYLSASYER 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 565388484  152 VRSELSDPHQVIEAKTLQLSNLHSATELLQSTIRTIRLSKKL 193
Cdd:pfam10392  91 LKSDVLEPYERALKLQSALKRLHQTTDLLRALLRFLHLSRQL 132
 
Name Accession Description Interval E-value
COG5 pfam10392
Golgi transport complex subunit 5; The COG complex, the peripheral membrane oligomeric protein ...
 80-193 1.34e-17

Golgi transport complex subunit 5; The COG complex, the peripheral membrane oligomeric protein complex involved in intra-Golgi protein trafficking, consists of eight subunits arranged in two lobes bridged by Cog1. Cog5 is in the smaller, B lobe, bound in with Cog6-8, and is itself bound to Cog1 as well as, strongly, to Cog7.


Pssm-ID: 192566  Cd Length: 132  Bit Score: 79.66  E-value: 1.34e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 565388484   80 TRFSSAALSS--------GSTASRIEKLQEGLRLLDHQLRHEVLTRHHDLLNQLTSLRAAESALSTLRSSVSSLQSSLRR 151
Cdd:pfam10392  11 KSFANALLLAtnnnddtpLDLSTPLKRLNYDIQELDRRIRTLITSNHLELLSHLSSIKSASSILSTLKSSLEYLSASYER 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 565388484  152 VRSELSDPHQVIEAKTLQLSNLHSATELLQSTIRTIRLSKKL 193
Cdd:pfam10392  91 LKSDVLEPYERALKLQSALKRLHQTTDLLRALLRFLHLSRQL 132
 
Name Accession Description Interval E-value
COG5 pfam10392
Golgi transport complex subunit 5; The COG complex, the peripheral membrane oligomeric protein ...
 80-193 1.34e-17

Golgi transport complex subunit 5; The COG complex, the peripheral membrane oligomeric protein complex involved in intra-Golgi protein trafficking, consists of eight subunits arranged in two lobes bridged by Cog1. Cog5 is in the smaller, B lobe, bound in with Cog6-8, and is itself bound to Cog1 as well as, strongly, to Cog7.


Pssm-ID: 192566  Cd Length: 132  Bit Score: 79.66  E-value: 1.34e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 565388484   80 TRFSSAALSS--------GSTASRIEKLQEGLRLLDHQLRHEVLTRHHDLLNQLTSLRAAESALSTLRSSVSSLQSSLRR 151
Cdd:pfam10392  11 KSFANALLLAtnnnddtpLDLSTPLKRLNYDIQELDRRIRTLITSNHLELLSHLSSIKSASSILSTLKSSLEYLSASYER 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 565388484  152 VRSELSDPHQVIEAKTLQLSNLHSATELLQSTIRTIRLSKKL 193
Cdd:pfam10392  91 LKSDVLEPYERALKLQSALKRLHQTTDLLRALLRFLHLSRQL 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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