|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
6-961 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1207.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 6 TAREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPMAKLSRAANTQKCIRAGGKHNDL 85
Cdd:PLN02900 12 PGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 86 DDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAagLEPDLECRQIWQNLgLDEAK 165
Cdd:PLN02900 92 DDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEER 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 166 ILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLE 245
Cdd:PLN02900 169 VLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDTGMGLE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 246 RLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDTDGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLR 325
Cdd:PLN02900 249 RLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVLR 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 326 RILRRAVRYSHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDC-- 403
Cdd:PLN02900 329 RLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAAKANgg 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 404 QTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQ--GKGAGGEDLIMlDIYAIEELRAKGLEAT 481
Cdd:PLN02900 409 PVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRaaHLKAGGGAIEL-AAEATSWLQKQGVAAT 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 482 DDSPKYNYHSDSSgsyvfectvATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVkvddsSEDKTEF 561
Cdd:PLN02900 488 DDFLKYDWLSDHE---------AVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLE-----GSGGAVV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 562 TVKNAQVRGGYVLHIGTIY-GNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGD-ADQKGSLVAPDRLRFDFT 639
Cdd:PLN02900 554 EVSDVQKAGGFVLHIGTVTeGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDhVDQKGSLVAFEKLRFDFS 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 640 AKGAMSTEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGvpvsellddpsgpaGSLtS 719
Cdd:PLN02900 634 HGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVSVG--------------GVY-S 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 720 VEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAmevkvkAQSAPNKDVQKEIADLG 799
Cdd:PLN02900 699 MELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDS------ALKVEGSDLEKKVASLK 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 800 EVLATAVIPQWQKDEQRETLKSL-KKVMDDLDRASKADVQKrVLEKTKQLIDS--NPNQPLVILEMESGASAKALNEAL- 875
Cdd:PLN02900 773 SRVDAAVIPAAKKEEIRARVSALqKELRAAQKEAAALRAKL-AVAKATELASKalSAGKSVLVARLDVGVDAAALKEAAe 851
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 876 KLFKTHsPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATGKNVGCLQEALQLA 955
Cdd:PLN02900 852 KVIAKL-GDPAAVVLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKA 930
|
....*.
gi 564395732 956 TSFAQL 961
Cdd:PLN02900 931 RAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
5-963 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1018.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 5 LTAREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPmaklsRAANTQKCIRAGGKHND 84
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYP-----RATTSQKCVRTGGKHND 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 85 LDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGD-EAAglepdlecrQIWQNL-GLD 162
Cdd:COG0013 77 LENVGYTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDdEAY---------DIWKKEiGVP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 163 EAKILPGNMKDNFWEMGDTGPCGPCSEIHYDR----IGGRDAahLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSI 238
Cdd:COG0013 148 EERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeyGGGPPG--SPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNI 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 239 DTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGArpytgKVGAEDTDgiDMAYRVLADHARTITVALADGGRPDNT 318
Cdd:COG0013 226 DTGMGLERIAAVLQGVHSNYETDLFRPLIEAAAELTGV-----KYGADEED--DVSLRVIADHIRAVAFLIADGVLPSNE 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 319 GRGYVLRRILRRAVRYSHeKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQ 398
Cdd:COG0013 299 GRGYVLRRILRRAVRHGR-LLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIA 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 399 SLGDC--QTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEE----RKLAQLKSQGKGAGGEDLImldiyaIEE 472
Cdd:COG0013 378 KLKAAggKVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAmeeqRERARAAAKFSGDAAVDGV------WRE 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 473 LRAKGLEatddspkynyhSDSSGsYVFECTVATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVKvd 552
Cdd:COG0013 452 LLEEGGP-----------TEFVG-YDTLEAEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEG-- 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 553 dsseDKTEFTVKNAQ-VRGGYVLHIGTI-YGNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGD-ADQKGSLV 629
Cdd:COG0013 518 ----DGGVFEVTDTQkPPGGLIVHIGKVeEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEhVTQAGSLV 593
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 630 APDRLRFDFTAKGAMSTEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAiQGLRAVFDETYPDPVRVVSIGvPVSelldd 709
Cdd:COG0013 594 APDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG-DFS----- 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 710 psgpagsltsVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAMeVKVKAQSAPNK 789
Cdd:COG0013 667 ----------RELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLREQEALLKELAEL-LKAPPEELPER 735
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 790 dvqkeIADLgevlatavipqwqKDEQRETLKSLKKVMDDLDRASKADVQKRVLEktkqlIDsnpNQPLVILEMEsGASAK 869
Cdd:COG0013 736 -----VEAL-------------LEELKELEKELEQLKAKLASAAADDLLAQAEE-----IG---GVKVLAARVE-GVDAK 788
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 870 ALNEALKLFKTHSPQTSAMLFTVDNeaGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGK-DMsAQATGKNVGCL 948
Cdd:COG0013 789 DLRDLADDLKDKLGSGVVVLASVAD--GKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRpDM-AQAGGKDPSKL 865
|
970
....*....|....*
gi 564395732 949 QEALQLATSFAQLRL 963
Cdd:COG0013 866 DEALAAVKEWLAEKL 880
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
9-597 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 835.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 9 EIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDpshpMAKLSRAANTQKCIRAGgkhnDLDDV 88
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVA----KPPYNRATNSQKCIRAG----DLENV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 89 GKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEaaglepdlECRQIWQNL-GLDEAKIL 167
Cdd:pfam01411 73 GRTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERIL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 168 PGNMKDNFWEMGDTGPCGPCSEIHYDR---IGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGL 244
Cdd:pfam01411 145 RFGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 245 ERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTgkvgaedTDGIDMAYRVLADHARTITVALADGGRPDNTGRGYVL 324
Cdd:pfam01411 225 ERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 325 RRILRRAVRYSHeKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDC- 403
Cdd:pfam01411 298 RRILRRAVRHAK-KLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKGk 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 404 QTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDliMLDIYAIEELRakgleATDD 483
Cdd:pfam01411 377 KTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGE--KLDVSALKELP-----ATTE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 484 SPKYNYHSDSsgsyvfectvATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVKvddsseDKTEFTV 563
Cdd:pfam01411 450 FLGYDDLESE----------AKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIG------DGGEFRV 513
|
570 580 590
....*....|....*....|....*....|....*
gi 564395732 564 KNAQVRGGYVLHIGTI-YGNLRVGDQVRLFIDEPR 597
Cdd:pfam01411 514 TDVQKYGGVVVHKGKLeSGKLKVGDKVIAVIDEDR 548
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
9-942 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 822.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 9 EIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPmaklsRAANTQKCIRAggkhNDLDDV 88
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSN-----RLTNAQPCIRL----NDLENV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 89 GKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAAGLepdlecrqIWQNLGLDEAKILP 168
Cdd:TIGR00344 72 GRTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYK--------IWEKIGIPADRIIK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 169 GNMKDNFWEMGDtGPCGPCSEIHYDRIGGRDAAHLVnqDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLERLV 248
Cdd:TIGR00344 144 CDAKDNFWDMGD-GPCGPCTEIYYDFVGGKPGEPLE--ENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 249 SVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDTDGID--MAYRVLADHARTITVALADGGRPDNTGRGYVLRR 326
Cdd:TIGR00344 221 AVLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRR 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 327 ILRRAVRYSHeKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDcQTI 406
Cdd:TIGR00344 301 LIRRALRHGK-KLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGK-KEL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 407 PGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLdiyaieelrakgLEATDDSPK 486
Cdd:TIGR00344 379 DGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIAL------------VNVYPATEF 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 487 YNYHSdssgsyvFECTvATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVKvddsseDKTEFTVKNA 566
Cdd:TIGR00344 447 LGYDD-------LEFE-AKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA------NDGKFRVVDV 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 567 QVRGGYVLHIGTIY-GNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGD-ADQKGSLVAPDRLRFDFTAKGAM 644
Cdd:TIGR00344 513 QKPNGVVFHFGEVEgGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNhVWQAGSLVSFKKLRFDFSHFRAL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 645 STEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIQGLRAvFDETYP--DPVRVVSIGvpvsellDdpsgpagslTSVEF 722
Cdd:TIGR00344 593 TREELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFAL-FGEKYVpgEKVRVVSVG-------D---------FSVEL 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 723 CGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRK--------SETLKKSLSAMEVKVKAQSAPNKDVQKE 794
Cdd:TIGR00344 656 CGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEqedklkelADILKVTPNELPKKVERFFEEWKALQKE 735
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 795 IADLGEVLATAVIPQWQKdeQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLidsnpnqplvilemesGASAKALnea 874
Cdd:TIGR00344 736 LESLKLKIADQKIDELKD--KAETINGVKVLVEVVDAKDMKSLKTMADRLKSKL----------------GSAIYVL--- 794
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564395732 875 lklfkthspqtsamlftVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATG 942
Cdd:TIGR00344 795 -----------------ASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
7-254 |
9.49e-137 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 409.06 E-value: 9.49e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 7 AREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPmaklsRAANTQKCIRAGGKHNdld 86
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPAN-----RLVNSQKCIRAGDIDN--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 87 dVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDeaaglepDLECRQIWQNLGLDEAKI 166
Cdd:cd00673 73 -VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 167 LPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLER 246
Cdd:cd00673 145 ERIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLER 224
|
....*...
gi 564395732 247 LVSVLQNK 254
Cdd:cd00673 225 LVWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
694-752 |
1.12e-11 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 60.09 E-value: 1.12e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 564395732 694 VRVVSIGVpvsellddpsgpagslTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRI 752
Cdd:smart00863 1 VRVVSIGD----------------FSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
6-961 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1207.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 6 TAREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPMAKLSRAANTQKCIRAGGKHNDL 85
Cdd:PLN02900 12 PGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 86 DDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAagLEPDLECRQIWQNLgLDEAK 165
Cdd:PLN02900 92 DDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEER 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 166 ILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLE 245
Cdd:PLN02900 169 VLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDTGMGLE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 246 RLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDTDGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLR 325
Cdd:PLN02900 249 RLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVLR 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 326 RILRRAVRYSHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDC-- 403
Cdd:PLN02900 329 RLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAAKANgg 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 404 QTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQ--GKGAGGEDLIMlDIYAIEELRAKGLEAT 481
Cdd:PLN02900 409 PVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRaaHLKAGGGAIEL-AAEATSWLQKQGVAAT 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 482 DDSPKYNYHSDSSgsyvfectvATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVkvddsSEDKTEF 561
Cdd:PLN02900 488 DDFLKYDWLSDHE---------AVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLE-----GSGGAVV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 562 TVKNAQVRGGYVLHIGTIY-GNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGD-ADQKGSLVAPDRLRFDFT 639
Cdd:PLN02900 554 EVSDVQKAGGFVLHIGTVTeGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDhVDQKGSLVAFEKLRFDFS 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 640 AKGAMSTEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGvpvsellddpsgpaGSLtS 719
Cdd:PLN02900 634 HGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVSVG--------------GVY-S 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 720 VEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAmevkvkAQSAPNKDVQKEIADLG 799
Cdd:PLN02900 699 MELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDS------ALKVEGSDLEKKVASLK 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 800 EVLATAVIPQWQKDEQRETLKSL-KKVMDDLDRASKADVQKrVLEKTKQLIDS--NPNQPLVILEMESGASAKALNEAL- 875
Cdd:PLN02900 773 SRVDAAVIPAAKKEEIRARVSALqKELRAAQKEAAALRAKL-AVAKATELASKalSAGKSVLVARLDVGVDAAALKEAAe 851
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 876 KLFKTHsPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATGKNVGCLQEALQLA 955
Cdd:PLN02900 852 KVIAKL-GDPAAVVLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKA 930
|
....*.
gi 564395732 956 TSFAQL 961
Cdd:PLN02900 931 RAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
5-963 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1018.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 5 LTAREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPmaklsRAANTQKCIRAGGKHND 84
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYP-----RATTSQKCVRTGGKHND 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 85 LDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGD-EAAglepdlecrQIWQNL-GLD 162
Cdd:COG0013 77 LENVGYTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDdEAY---------DIWKKEiGVP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 163 EAKILPGNMKDNFWEMGDTGPCGPCSEIHYDR----IGGRDAahLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSI 238
Cdd:COG0013 148 EERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeyGGGPPG--SPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNI 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 239 DTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGArpytgKVGAEDTDgiDMAYRVLADHARTITVALADGGRPDNT 318
Cdd:COG0013 226 DTGMGLERIAAVLQGVHSNYETDLFRPLIEAAAELTGV-----KYGADEED--DVSLRVIADHIRAVAFLIADGVLPSNE 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 319 GRGYVLRRILRRAVRYSHeKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQ 398
Cdd:COG0013 299 GRGYVLRRILRRAVRHGR-LLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIA 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 399 SLGDC--QTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEE----RKLAQLKSQGKGAGGEDLImldiyaIEE 472
Cdd:COG0013 378 KLKAAggKVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAmeeqRERARAAAKFSGDAAVDGV------WRE 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 473 LRAKGLEatddspkynyhSDSSGsYVFECTVATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVKvd 552
Cdd:COG0013 452 LLEEGGP-----------TEFVG-YDTLEAEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEG-- 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 553 dsseDKTEFTVKNAQ-VRGGYVLHIGTI-YGNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGD-ADQKGSLV 629
Cdd:COG0013 518 ----DGGVFEVTDTQkPPGGLIVHIGKVeEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEhVTQAGSLV 593
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 630 APDRLRFDFTAKGAMSTEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAiQGLRAVFDETYPDPVRVVSIGvPVSelldd 709
Cdd:COG0013 594 APDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG-DFS----- 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 710 psgpagsltsVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAMeVKVKAQSAPNK 789
Cdd:COG0013 667 ----------RELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLREQEALLKELAEL-LKAPPEELPER 735
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 790 dvqkeIADLgevlatavipqwqKDEQRETLKSLKKVMDDLDRASKADVQKRVLEktkqlIDsnpNQPLVILEMEsGASAK 869
Cdd:COG0013 736 -----VEAL-------------LEELKELEKELEQLKAKLASAAADDLLAQAEE-----IG---GVKVLAARVE-GVDAK 788
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 870 ALNEALKLFKTHSPQTSAMLFTVDNeaGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGK-DMsAQATGKNVGCL 948
Cdd:COG0013 789 DLRDLADDLKDKLGSGVVVLASVAD--GKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRpDM-AQAGGKDPSKL 865
|
970
....*....|....*
gi 564395732 949 QEALQLATSFAQLRL 963
Cdd:COG0013 866 DEALAAVKEWLAEKL 880
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
9-597 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 835.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 9 EIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDpshpMAKLSRAANTQKCIRAGgkhnDLDDV 88
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVA----KPPYNRATNSQKCIRAG----DLENV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 89 GKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEaaglepdlECRQIWQNL-GLDEAKIL 167
Cdd:pfam01411 73 GRTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERIL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 168 PGNMKDNFWEMGDTGPCGPCSEIHYDR---IGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGL 244
Cdd:pfam01411 145 RFGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 245 ERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTgkvgaedTDGIDMAYRVLADHARTITVALADGGRPDNTGRGYVL 324
Cdd:pfam01411 225 ERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 325 RRILRRAVRYSHeKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDC- 403
Cdd:pfam01411 298 RRILRRAVRHAK-KLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKGk 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 404 QTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDliMLDIYAIEELRakgleATDD 483
Cdd:pfam01411 377 KTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGE--KLDVSALKELP-----ATTE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 484 SPKYNYHSDSsgsyvfectvATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVKvddsseDKTEFTV 563
Cdd:pfam01411 450 FLGYDDLESE----------AKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIG------DGGEFRV 513
|
570 580 590
....*....|....*....|....*....|....*
gi 564395732 564 KNAQVRGGYVLHIGTI-YGNLRVGDQVRLFIDEPR 597
Cdd:pfam01411 514 TDVQKYGGVVVHKGKLeSGKLKVGDKVIAVIDEDR 548
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
9-942 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 822.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 9 EIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPmaklsRAANTQKCIRAggkhNDLDDV 88
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSN-----RLTNAQPCIRL----NDLENV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 89 GKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAAGLepdlecrqIWQNLGLDEAKILP 168
Cdd:TIGR00344 72 GRTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYK--------IWEKIGIPADRIIK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 169 GNMKDNFWEMGDtGPCGPCSEIHYDRIGGRDAAHLVnqDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLERLV 248
Cdd:TIGR00344 144 CDAKDNFWDMGD-GPCGPCTEIYYDFVGGKPGEPLE--ENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 249 SVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDTDGID--MAYRVLADHARTITVALADGGRPDNTGRGYVLRR 326
Cdd:TIGR00344 221 AVLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRR 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 327 ILRRAVRYSHeKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDcQTI 406
Cdd:TIGR00344 301 LIRRALRHGK-KLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGK-KEL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 407 PGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLdiyaieelrakgLEATDDSPK 486
Cdd:TIGR00344 379 DGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIAL------------VNVYPATEF 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 487 YNYHSdssgsyvFECTvATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIFDEGYLVKvddsseDKTEFTVKNA 566
Cdd:TIGR00344 447 LGYDD-------LEFE-AKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA------NDGKFRVVDV 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 567 QVRGGYVLHIGTIY-GNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGD-ADQKGSLVAPDRLRFDFTAKGAM 644
Cdd:TIGR00344 513 QKPNGVVFHFGEVEgGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNhVWQAGSLVSFKKLRFDFSHFRAL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 645 STEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIQGLRAvFDETYP--DPVRVVSIGvpvsellDdpsgpagslTSVEF 722
Cdd:TIGR00344 593 TREELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFAL-FGEKYVpgEKVRVVSVG-------D---------FSVEL 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 723 CGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRK--------SETLKKSLSAMEVKVKAQSAPNKDVQKE 794
Cdd:TIGR00344 656 CGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEqedklkelADILKVTPNELPKKVERFFEEWKALQKE 735
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 795 IADLGEVLATAVIPQWQKdeQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLidsnpnqplvilemesGASAKALnea 874
Cdd:TIGR00344 736 LESLKLKIADQKIDELKD--KAETINGVKVLVEVVDAKDMKSLKTMADRLKSKL----------------GSAIYVL--- 794
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564395732 875 lklfkthspqtsamlftVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATG 942
Cdd:TIGR00344 795 -----------------ASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
5-755 |
4.27e-146 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 446.91 E-value: 4.27e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 5 LTAREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHpmaklSRAANTQKCIRAGgkhnD 84
Cdd:PRK01584 1 MTLDELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSG-----TRLVDVQKCLRTG----D 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 85 LDDVGkDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQE--FGIPVERLYVTYFGGDEAAglEPDLECRQIWQNLGLD 162
Cdd:PRK01584 72 IDEVG-DLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTSPdyLNIPKDKLYVTVFEGDEEI--PRDEETASVWESLGIP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 163 EAKILPGNMKDNFW-EMGDTGPCGPCSEIHYDRigGRDAAHlvNQDDPNV-----LEIWNLVFIQYNRESDGVLKPLPKK 236
Cdd:PRK01584 149 KDRIFYLSREHNWWgPVGETGPCGPDTEIFVDT--GKPKCS--VNCRPTCscgkyFEIWNNVFMQYNKDEDGNYEELKRK 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 237 SIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARpyTGKVGAEDTdgidmAYRVLADHARTITVALAD--GGR 314
Cdd:PRK01584 225 CVDTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEKISGKI--YGQNEEDDR-----SIRIIADHIRAACFILGDpfVVL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 315 PDNTGRGYVLRRILRRAVRYShEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILD 394
Cdd:PRK01584 298 PSNVGQGYVLRRLIRRSIRHA-KKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFI 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 395 RKIQSLGDCQTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQgKGAggedlimldiyaieelr 474
Cdd:PRK01584 377 KLIPNLGSSKIIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSK-KGA----------------- 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 475 akgleatddspkynyhsdssgsyvfectvatvlalrrEKMFvdevvtgqecgvvldktcfyaeQGGqifdegylvkVDDS 554
Cdd:PRK01584 439 -------------------------------------DKVF----------------------KGG----------LADH 449
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 555 SEDKTEFtvknaqvrggyvlhigtiygnlrvgdqvrlfideprrrpvmsnHTATHILNFALRSVLGD-ADQKGSLVAPDR 633
Cdd:PRK01584 450 SYETTKL-------------------------------------------HTATHLLHKALRLVLGDhVRQKGSNITAER 486
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 634 LRFDFTAKGAMSTEQIKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIqGLRAVFDETYPDPVRVVSIGVpvsellddpsgp 713
Cdd:PRK01584 487 LRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVKKEVMSLEEAREK-GAMALFGEKYEDIVKVYEIDG------------ 553
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 564395732 714 agslTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAV 755
Cdd:PRK01584 554 ----FSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAI 591
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
7-254 |
9.49e-137 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 409.06 E-value: 9.49e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 7 AREIRERFINYFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTVDPSHPmaklsRAANTQKCIRAGGKHNdld 86
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPAN-----RLVNSQKCIRAGDIDN--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 87 dVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDeaaglepDLECRQIWQNLGLDEAKI 166
Cdd:cd00673 73 -VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 167 LPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLER 246
Cdd:cd00673 145 ERIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLER 224
|
....*...
gi 564395732 247 LVSVLQNK 254
Cdd:cd00673 225 LVWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
489-753 |
3.27e-34 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 131.47 E-value: 3.27e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 489 YHSDSsgsYVFECTvATVLALRrekmfvdevvtgQECGVVLDKTCFYAEQGGQIFDEGYLVKvddsseDKTEFTVKNAQV 568
Cdd:COG2872 6 YLEDS---YLKEFE-ATVTAVT------------EEGGVVLDRTAFYPTGGGQPGDTGTLVW------DGKEIRVVDVRK 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 569 RGGYVLHIGTIYGNLRVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGdADQKGSLVAPDRLRFDFtAKGAMSTEQ 648
Cdd:COG2872 64 EDGEIVHVLEGAPLPEVGDEVTGEIDWERRYRHMRLHTALHLLSAVVYREYG-APVTGGQIGEDRARIDF-DLPEFDEED 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 649 IKKTEEIVNGMIEAAKPVYTLDCPLAAAKAIQGL-RAVFDETYP--DPVRVVSI-GVPVSellddPsgpagsltsvefCG 724
Cdd:COG2872 142 LEEIEAEANELIAADLPVRIYWITREELEAIPGLvRTMSVLPPPgvGRVRIVEIgGVDLQ-----P------------CG 204
|
250 260
....*....|....*....|....*....
gi 564395732 725 GTHLRNSSHAGAFVIVTEEAIAKGIRRIV 753
Cdd:COG2872 205 GTHVANTGEIGRIKITKIEKKGKGNRRVY 233
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
813-959 |
1.49e-18 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 82.87 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 813 DEQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLIdsnpNQPLVILEMESGASAKALNEALKLFKTHSPQTSAMLFTV 892
Cdd:pfam02272 2 ESLNEELKELEKELEELKEALALLKAKELLEKAEEIN----GVKVLVAEVGEGWDAGALGIAADRLKKKLGDPVIVLVAK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564395732 893 DNEaGKITCLCQVPQNaanRGLKASEWVQQVSGLMDGKGGGKDMsAQATGKNVGCLQEALQLATSFA 959
Cdd:pfam02272 78 EDG-DKVKVSARSSKD---KGVDAGELLKEVAAILGGGGGGHDL-AAGAGIDAEKLDEALELLEEAI 139
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
525-753 |
8.17e-13 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 68.96 E-value: 8.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 525 CGVVLDKTCFYAEQGGQIFDEGYLVkvddSSEDKTEFTVKNAQVRGGYVLHIGTIYGN-------LRVGDQVRLFIDEPR 597
Cdd:PLN02961 3 IALVLDRTIFHPQGGGQPSDTGRIV----ISGGDTKFSVQDVRRKDGVVYHYGVFEGSnpesaspFEAGDEVTVTVDESR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 598 RRPVMSNHTATHILNFALRSVlgdadQKGSLVAPDRLRFDFTA----KGAMSTEQIKKT----EEIVNGMIEAAKPVYTL 669
Cdd:PLN02961 79 RKLHSRLHSAGHLLDVCMARV-----GLGPLEPGKGYHFPDGPfveyKGKIPQGELDSKqdelEAEANELIAEGGKVSAA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395732 670 DCPLAAAKAIQGLRA---VFDETYPdpvRVVSIGvpvsellDDPSGPagsltsvefCGGTHLRNSSHAGAfVIVTEEAIA 746
Cdd:PLN02961 154 VLPYDEAAELCGGSLpdyIAKDSTP---RIVKIG-------DSPGCP---------CGGTHVADVSEITS-VKVTQIRVK 213
|
....*..
gi 564395732 747 KGIRRIV 753
Cdd:PLN02961 214 KGVTRVS 220
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
694-752 |
3.01e-12 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 61.69 E-value: 3.01e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 564395732 694 VRVVSIGVpvsellddpsgpagslTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRI 752
Cdd:pfam07973 1 VRVVSIGD----------------FDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
694-752 |
1.12e-11 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 60.09 E-value: 1.12e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 564395732 694 VRVVSIGVpvsellddpsgpagslTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRI 752
Cdd:smart00863 1 VRVVSIGD----------------FSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| mtIF2_IVc |
cd03692 |
C2 subdomain of domain IV in mitochondrial translation initiation factor 2; This model ... |
495-531 |
1.93e-03 |
|
C2 subdomain of domain IV in mitochondrial translation initiation factor 2; This model represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor EF-Tu. The C-terminal part of mtIF2 contains the entire fMet-tRNAfmet binding site of IF-2 and is resistant to proteolysis. This C-terminal portion consists of two domains, IF2 C1 and IF2 C2. IF2 C2 has been shown to contain all molecular determinants necessary and sufficient for the recognition and binding of fMet-tRNAfMet. Like IF2 from certain prokaryotes such as Thermus thermophilus, mtIF2lacks domain II which is thought to be involved in binding of E.coli IF-2 to 30S subunits.
Pssm-ID: 293893 [Multi-domain] Cd Length: 84 Bit Score: 38.24 E-value: 1.93e-03
10 20 30
....*....|....*....|....*....|....*..
gi 564395732 495 GSYVFECTVATvlaLRREKMFVDEVVTGQECGVVLDK 531
Cdd:cd03692 39 GEVIYEGKISS---LKRFKDDVKEVKKGYECGITLEN 72
|
|
| |
