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Conserved domains on  [gi|564395504|ref|XP_006255544|]
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solute carrier family 12 member 4 isoform X1 [Rattus norvegicus]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
11-1054 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1351.30  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    11 NHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGT 89
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    90 LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGA 169
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   170 VGLCFYLGTTFAAAMYILGAIEILLTyiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 249
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   250 LACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 329
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   330 nvtEIPGIPGAAAGvlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNR 409
Cdd:TIGR00930  271 ---FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANI 302
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   410 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTL 468
Cdd:TIGR00930  303 SGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSL 382
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   469 AWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVA 547
Cdd:TIGR00930  383 VSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIA 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   548 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAE 627
Cdd:TIGR00930  463 PIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPD 542
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   628 KEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 707
Cdd:TIGR00930  543 VNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLEC 618
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   708 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCT 787
Cdd:TIGR00930  619 VKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDA 697
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   788 TAAHLALLVPKNIAFYPSNH--------------------------------------ERYLEGHIDVWWIVHDGGMLML 829
Cdd:TIGR00930  698 FDAHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLL 777
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   830 LPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMR 909
Cdd:TIGR00930  778 LPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFR 852
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   910 LTKTERDREAqlvKDRHsalrleslysdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfrelvhiKPDQSNVRRMH 989
Cdd:TIGR00930  853 LHKTEKDREA---KDPK------------------------MTWTKPWKITD-----------------AELQSNVRKSY 888
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564395504   990 TAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1054
Cdd:TIGR00930  889 RQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
11-1054 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1351.30  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    11 NHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGT 89
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    90 LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGA 169
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   170 VGLCFYLGTTFAAAMYILGAIEILLTyiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 249
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   250 LACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 329
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   330 nvtEIPGIPGAAAGvlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNR 409
Cdd:TIGR00930  271 ---FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANI 302
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   410 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTL 468
Cdd:TIGR00930  303 SGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSL 382
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   469 AWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVA 547
Cdd:TIGR00930  383 VSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIA 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   548 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAE 627
Cdd:TIGR00930  463 PIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPD 542
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   628 KEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 707
Cdd:TIGR00930  543 VNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLEC 618
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   708 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCT 787
Cdd:TIGR00930  619 VKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDA 697
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   788 TAAHLALLVPKNIAFYPSNH--------------------------------------ERYLEGHIDVWWIVHDGGMLML 829
Cdd:TIGR00930  698 FDAHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLL 777
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   830 LPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMR 909
Cdd:TIGR00930  778 LPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFR 852
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   910 LTKTERDREAqlvKDRHsalrleslysdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfrelvhiKPDQSNVRRMH 989
Cdd:TIGR00930  853 LHKTEKDREA---KDPK------------------------MTWTKPWKITD-----------------AELQSNVRKSY 888
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564395504   990 TAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1054
Cdd:TIGR00930  889 RQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
92-664 3.13e-50

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 184.83  E-value: 3.13e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    92 GVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVpAGGSYFMISRSLGPEFGGAVG 171
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   172 L--CFYLGTTFAAAmyiLGAIEILLTYIAPPAAIFYPSGThdmssatlnnmrvyGTIFLTFMTLVVFVGVKYVNKFASLF 249
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDIPYLWVW--------------GAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   250 LACVIISILSIYVGGIKSAFDPpvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 329
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIILLSGG---------------------------------------------------------- 164
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   330 nvteipgipGAAAGVLQENLWSAYLEKgevvekhglpstdtlglkeslslYVVADIATSFTVLVGIFFPSVTGIMAGSNR 409
Cdd:pfam00324  165 ---------NPNDGAIFRYLGDNGGKN-----------------------NFPPGFGKGFISVFVIAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   410 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVV------GTLAWPSpwVIVVGSFFS 483
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTA 290
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   484 TCGAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHGKANGEPTWALLLTALIAELGILIASLdmVAPILSMFFLMCYLFVNL 563
Cdd:pfam00324  291 ALSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGL 366
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   564 ACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR 643
Cdd:pfam00324  367 IVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVL 446
                          570       580
                   ....*....|....*....|.
gi 564395504   644 YALLRLEEGPPHTKNWRPQLL 664
Cdd:pfam00324  447 LFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
100-624 1.61e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 135.02  E-value: 1.61e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  100 NIFGVILFLRLTWMVGTAGvLQALLIVLICCCCTLLTAISMSAIATNgvVP-AGGSYFMISRSLGPEFGGAVGLCFYLGT 178
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLLSY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  179 TFAAAMYILGAIEILltyiappaAIFYPSGTHDmssatlnnmrVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISIL 258
Cdd:COG0531   102 VLAVAAVAVAFGGYL--------SSLFPAGGSV----------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  259 SIYVGGIksafdppvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdPYFLLNNVTEIPGIP 338
Cdd:COG0531   164 LFIVVGL----------------------------------------------------------FAFDPANFTPFLPAG 185
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  339 GAAAGVlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFpSVTGIMAGSNRSGDLRDAQK 418
Cdd:COG0531   186 GGLSGV--------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  419 SIPVGTILAIVTTSLVYFSSVILFGacieGVVLRDKYGDGVSRNLVVGTLAWPSP--WVIVVGSFFSTCGAGLQSLTGAP 496
Cdd:COG0531   221 NIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  497 RLLQAIAKDNIIPflRVFGH-GKANGEPTWALLLTALIAELGILI--ASLDMVAPILSMFFLMCYLFVNLACAVQtLLRT 573
Cdd:COG0531   297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-RRRR 373
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564395504  574 PNWRPRFKYYHWALSFLGMSLCLALMFVS---SWYYALVAMVIAGMIYKYIEYQ 624
Cdd:COG0531   374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
11-1054 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1351.30  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    11 NHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGT 89
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    90 LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGA 169
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   170 VGLCFYLGTTFAAAMYILGAIEILLTyiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 249
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   250 LACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 329
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   330 nvtEIPGIPGAAAGvlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNR 409
Cdd:TIGR00930  271 ---FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANI 302
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   410 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTL 468
Cdd:TIGR00930  303 SGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSL 382
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   469 AWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVA 547
Cdd:TIGR00930  383 VSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIA 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   548 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAE 627
Cdd:TIGR00930  463 PIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPD 542
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   628 KEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 707
Cdd:TIGR00930  543 VNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLEC 618
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   708 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCT 787
Cdd:TIGR00930  619 VKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDA 697
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   788 TAAHLALLVPKNIAFYPSNH--------------------------------------ERYLEGHIDVWWIVHDGGMLML 829
Cdd:TIGR00930  698 FDAHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLL 777
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   830 LPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMR 909
Cdd:TIGR00930  778 LPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFR 852
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   910 LTKTERDREAqlvKDRHsalrleslysdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfrelvhiKPDQSNVRRMH 989
Cdd:TIGR00930  853 LHKTEKDREA---KDPK------------------------MTWTKPWKITD-----------------AELQSNVRKSY 888
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564395504   990 TAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1054
Cdd:TIGR00930  889 RQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
92-664 3.13e-50

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 184.83  E-value: 3.13e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504    92 GVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVpAGGSYFMISRSLGPEFGGAVG 171
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   172 L--CFYLGTTFAAAmyiLGAIEILLTYIAPPAAIFYPSGThdmssatlnnmrvyGTIFLTFMTLVVFVGVKYVNKFASLF 249
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDIPYLWVW--------------GAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   250 LACVIISILSIYVGGIKSAFDPpvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 329
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIILLSGG---------------------------------------------------------- 164
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   330 nvteipgipGAAAGVLQENLWSAYLEKgevvekhglpstdtlglkeslslYVVADIATSFTVLVGIFFPSVTGIMAGSNR 409
Cdd:pfam00324  165 ---------NPNDGAIFRYLGDNGGKN-----------------------NFPPGFGKGFISVFVIAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   410 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVV------GTLAWPSpwVIVVGSFFS 483
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTA 290
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   484 TCGAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHGKANGEPTWALLLTALIAELGILIASLdmVAPILSMFFLMCYLFVNL 563
Cdd:pfam00324  291 ALSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGL 366
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   564 ACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR 643
Cdd:pfam00324  367 IVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVL 446
                          570       580
                   ....*....|....*....|.
gi 564395504   644 YALLRLEEGPPHTKNWRPQLL 664
Cdd:pfam00324  447 LFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
100-624 1.61e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 135.02  E-value: 1.61e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  100 NIFGVILFLRLTWMVGTAGvLQALLIVLICCCCTLLTAISMSAIATNgvVP-AGGSYFMISRSLGPEFGGAVGLCFYLGT 178
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLLSY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  179 TFAAAMYILGAIEILltyiappaAIFYPSGTHDmssatlnnmrVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISIL 258
Cdd:COG0531   102 VLAVAAVAVAFGGYL--------SSLFPAGGSV----------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  259 SIYVGGIksafdppvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdPYFLLNNVTEIPGIP 338
Cdd:COG0531   164 LFIVVGL----------------------------------------------------------FAFDPANFTPFLPAG 185
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  339 GAAAGVlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFpSVTGIMAGSNRSGDLRDAQK 418
Cdd:COG0531   186 GGLSGV--------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  419 SIPVGTILAIVTTSLVYFSSVILFGacieGVVLRDKYGDGVSRNLVVGTLAWPSP--WVIVVGSFFSTCGAGLQSLTGAP 496
Cdd:COG0531   221 NIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504  497 RLLQAIAKDNIIPflRVFGH-GKANGEPTWALLLTALIAELGILI--ASLDMVAPILSMFFLMCYLFVNLACAVQtLLRT 573
Cdd:COG0531   297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-RRRR 373
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564395504  574 PNWRPRFKYYHWALSFLGMSLCLALMFVS---SWYYALVAMVIAGMIYKYIEYQ 624
Cdd:COG0531   374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
678-1054 5.24e-24

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 106.16  E-value: 5.24e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   678 PRLLTFASQLKAGKGLTIVGSVIQGSFleSYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRH 757
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGRL--SQKLRSELQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKP 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   758 NSVVLGWPYGWRQSE----------------------------------------------------------------- 772
Cdd:pfam03522   80 NILLMGYKSDWRTCDkeeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   773 DPRAWKTFIDTVRCTTAAHLALLV--------------------PKNIAFYPSNHERYLE-----------GHIDVWWIV 821
Cdd:pfam03522  160 NSKQDDDKSKLSKKDSNLSLSPDKstknpsgkdssksdklkkksPSIILRTASNEKEILNnitqfqkkqkkGTIDVWWLY 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   822 HDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLE-AEVEVVemhnSDISAYTYERTLMMEQ 900
Cdd:pfam03522  240 DDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDELEEEQRNMASLLSKFRIDySDLTVI----PDITKKPKKETKKFFD 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   901 rsQMLRQMRLTKTErdreaqlvKDRHSALRLeslySDEEDESVtgadkiqmtwtRDKymaepwdpshapdNFRELvhikp 980
Cdd:pfam03522  316 --ELIEPFRLHEDD--------KEEESAEKI----TDSELEAL-----------KEK-------------TNRQL----- 352
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564395504   981 dqsnvrrmhtavKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1054
Cdd:pfam03522  353 ------------RLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease_2 pfam13520
Amino acid permease;
380-621 1.88e-13

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 73.88  E-value: 1.88e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   380 YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRdaQKSIPVGTILAIVTTSLVYFSSVILFGACI--EGVVLRDKYGD 457
Cdd:pfam13520  181 TFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYILVNIAFFGVVpdDEIALSSGLGQ 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   458 GVS---RNLVVGTLAWpspwVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTALIA 534
Cdd:pfam13520  259 VAAllfQAVGGKWGAI----IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILS 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564395504   535 ELGILIASLDMVAPI----LSMFFLMCYLFVNLACAVqtLLRTPNWRPRFKYYHWALSFLGMsLCLALMFVSSWYYALVA 610
Cdd:pfam13520  335 LILLLLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGI-LFSLFLIVALFFPPVGP 411
                          250
                   ....*....|.
gi 564395504   611 MVIAGMIYKYI 621
Cdd:pfam13520  412 ATGSSLNYAII 422
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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