|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
364-582 |
5.66e-123 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
:
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 364.58 E-value: 5.66e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 364 LRASHVRDAVAVIRYLVWLEKNVPQG-TVDEFSGAEQLEKLRGEEEFFSGSSFETISASGLNAALAHYSPTKELHRKLSS 442
Cdd:cd01085 2 MRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKISP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 443 DEIYLVDSGGQYWDGTTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVFPAATSGRMVEAFARKALWDVGLNYGHGTG 522
Cdd:cd01085 82 DGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGTG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2148433572 523 HGIGNFLCVHEWPVG--FQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVALVVEAKTKYPG 582
Cdd:cd01085 162 HGVGSFLNVHEGPQSisPAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFG 223
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
194-360 |
1.10e-63 |
|
Creatinase/Prolidase N-terminal domain;
:
Pssm-ID: 465053 Cd Length: 159 Bit Score: 208.11 E-value: 1.10e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 194 ERPPVPSEPIYALQEAFTGSTWQEKVAGIRSQMQEHHkaPTAVLLSALDETAWLFNLRGSDIPYNPFFYSYTLLTDSSIR 273
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKG--ADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEAT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 274 LFANKSRFSSETLQYLNSSctgplCVQVEDYGQVRDSVQAYtSGDVKVWIGTSYTSYGLYEVIPKEKLLEDTYSPVMVTK 353
Cdd:pfam16189 79 LFVDPEKLSDEVRAHLEEN-----GVEIRPYDDIYEDLAAL-AAGKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLMK 152
|
....*..
gi 2148433572 354 AVKNSKE 360
Cdd:pfam16189 153 AVKNETE 159
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
583-647 |
4.19e-23 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
:
Pssm-ID: 465052 Cd Length: 63 Bit Score: 92.86 E-value: 4.19e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2148433572 583 TYLTFEVVSLVPYDRNLIDVSLLSPEQLQYLNRYYQIIREKVGPELQRRqlQEEFSWLQRHTEPL 647
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEE--EDALEWLKRATRPI 63
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
52-183 |
1.20e-14 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
:
Pssm-ID: 460159 Cd Length: 128 Bit Score: 70.80 E-value: 1.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 52 RLTALRQQMYTQNLSAYIVPDTDahmseyigeydqRRAWITGFTGSAGVA-VVTMGKASLWTD-SRYWTQAeRQMDCNWE 129
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTSPE------------NLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAA-AESAPDFD 67
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2148433572 130 LHKEVGTTPIVTWLLTEIPVGARVGVDPFLFSINSWESYDKALqdSDRELVSIT 183
Cdd:pfam01321 68 VVPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEAL--PGAELVDVS 119
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
364-582 |
5.66e-123 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 364.58 E-value: 5.66e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 364 LRASHVRDAVAVIRYLVWLEKNVPQG-TVDEFSGAEQLEKLRGEEEFFSGSSFETISASGLNAALAHYSPTKELHRKLSS 442
Cdd:cd01085 2 MRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKISP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 443 DEIYLVDSGGQYWDGTTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVFPAATSGRMVEAFARKALWDVGLNYGHGTG 522
Cdd:cd01085 82 DGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGTG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2148433572 523 HGIGNFLCVHEWPVG--FQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVALVVEAKTKYPG 582
Cdd:cd01085 162 HGVGSFLNVHEGPQSisPAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFG 223
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
194-360 |
1.10e-63 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 208.11 E-value: 1.10e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 194 ERPPVPSEPIYALQEAFTGSTWQEKVAGIRSQMQEHHkaPTAVLLSALDETAWLFNLRGSDIPYNPFFYSYTLLTDSSIR 273
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKG--ADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEAT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 274 LFANKSRFSSETLQYLNSSctgplCVQVEDYGQVRDSVQAYtSGDVKVWIGTSYTSYGLYEVIPKEKLLEDTYSPVMVTK 353
Cdd:pfam16189 79 LFVDPEKLSDEVRAHLEEN-----GVEIRPYDDIYEDLAAL-AAGKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLMK 152
|
....*..
gi 2148433572 354 AVKNSKE 360
Cdd:pfam16189 153 AVKNETE 159
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
339-581 |
1.12e-56 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 194.27 E-value: 1.12e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 339 EKLLEDTYSPVMVTKAVKNSKEQTLLRASHVRDAVAVIRYLVWLEKNVPQGTVdefsgAEQLEKLRGEEEFfSGSSFETI 418
Cdd:COG0006 57 ERELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRPGVTEREV-----AAELEAAMRRRGA-EGPSFDTI 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 419 SASGLNAALAHYSPTkelHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVfPAATS 498
Cdd:COG0006 131 VASGENAAIPHYTPT---DRPLKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDEQREIYEAVLEAQEAAIAAL-KPGVT 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 499 GRMVEAFARKALWDVGL--NYGHGTGHGIGnfLCVHEWPVGFQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVALVVEA 576
Cdd:COG0006 207 GGEVDAAARDVLAEAGYgeYFPHGTGHGVG--LDVHEGPQISPGNDRPLEPGMVFTIEPGIYIPGIGGVRIEDTVLVTED 284
|
....*....
gi 2148433572 577 K----TKYP 581
Cdd:COG0006 285 GaevlTRLP 293
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
363-575 |
1.33e-48 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 169.34 E-value: 1.33e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 363 LLRASHVRDAVAVIRYLVWLEKNVpqgtvDEFSGAEQLEKLRGEEEFFSGSSFETISASGLNAALAHYSPTKelhRKLSS 442
Cdd:pfam00557 2 LMRKAARIAAAALEAALAAIRPGV-----TERELAAELEAARLRRGGARGPAFPPIVASGPNAAIPHYIPND---RVLKP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 443 DEIYLVDSGGQYWDG-TTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVFPAATsGRMVEAFARKALWDVGL--NYGH 519
Cdd:pfam00557 74 GDLVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVT-GGDVDAAAREVLEEAGLgeYFPH 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2148433572 520 GTGHGIGnfLCVHEWP-VGFQSSNIAMAKGMFTSIEPGYY-LDGEFGIRLEDVALVVE 575
Cdd:pfam00557 153 GLGHGIG--LEVHEGPyISRGGDDRVLEPGMVFTIEPGIYfIPGWGGVRIEDTVLVTE 208
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
583-647 |
4.19e-23 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 92.86 E-value: 4.19e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2148433572 583 TYLTFEVVSLVPYDRNLIDVSLLSPEQLQYLNRYYQIIREKVGPELQRRqlQEEFSWLQRHTEPL 647
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEE--EDALEWLKRATRPI 63
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
397-575 |
1.14e-16 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 82.29 E-value: 1.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 397 AEQLE---KLRGEEEffsgSSFETISASGLNAALAHyspTKELHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWGTPSAF 473
Cdd:PRK09795 164 AAELEwfmRQQGAEK----ASFDTIVASGWRGALPH---GKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVS 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 474 QKE-----AYTRVLIGNIDLSRLVFPAaTSGRMVEAFARKALWDVGLN--YGHGTGHGIGnfLCVHEWPVGFQSSNIAMA 546
Cdd:PRK09795 237 AEShplfnVYQIVLQAQLAAISAIRPG-VRCQQVDDAARRVITEAGYGdyFGHNTGHAIG--IEVHEDPRFSPRDTTTLQ 313
|
170 180
....*....|....*....|....*....
gi 2148433572 547 KGMFTSIEPGYYLDGEFGIRLEDVALVVE 575
Cdd:PRK09795 314 PGMLLTVEPGIYLPGQGGVRIEDVVLVTP 342
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
52-183 |
1.20e-14 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 70.80 E-value: 1.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 52 RLTALRQQMYTQNLSAYIVPDTDahmseyigeydqRRAWITGFTGSAGVA-VVTMGKASLWTD-SRYWTQAeRQMDCNWE 129
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTSPE------------NLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAA-AESAPDFD 67
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2148433572 130 LHKEVGTTPIVTWLLTEIPVGARVGVDPFLFSINSWESYDKALqdSDRELVSIT 183
Cdd:pfam01321 68 VVPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEAL--PGAELVDVS 119
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
364-582 |
5.66e-123 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 364.58 E-value: 5.66e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 364 LRASHVRDAVAVIRYLVWLEKNVPQG-TVDEFSGAEQLEKLRGEEEFFSGSSFETISASGLNAALAHYSPTKELHRKLSS 442
Cdd:cd01085 2 MRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKISP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 443 DEIYLVDSGGQYWDGTTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVFPAATSGRMVEAFARKALWDVGLNYGHGTG 522
Cdd:cd01085 82 DGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGTG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2148433572 523 HGIGNFLCVHEWPVG--FQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVALVVEAKTKYPG 582
Cdd:cd01085 162 HGVGSFLNVHEGPQSisPAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFG 223
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
194-360 |
1.10e-63 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 208.11 E-value: 1.10e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 194 ERPPVPSEPIYALQEAFTGSTWQEKVAGIRSQMQEHHkaPTAVLLSALDETAWLFNLRGSDIPYNPFFYSYTLLTDSSIR 273
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKG--ADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEAT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 274 LFANKSRFSSETLQYLNSSctgplCVQVEDYGQVRDSVQAYtSGDVKVWIGTSYTSYGLYEVIPKEKLLEDTYSPVMVTK 353
Cdd:pfam16189 79 LFVDPEKLSDEVRAHLEEN-----GVEIRPYDDIYEDLAAL-AAGKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLMK 152
|
....*..
gi 2148433572 354 AVKNSKE 360
Cdd:pfam16189 153 AVKNETE 159
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
339-581 |
1.12e-56 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 194.27 E-value: 1.12e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 339 EKLLEDTYSPVMVTKAVKNSKEQTLLRASHVRDAVAVIRYLVWLEKNVPQGTVdefsgAEQLEKLRGEEEFfSGSSFETI 418
Cdd:COG0006 57 ERELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRPGVTEREV-----AAELEAAMRRRGA-EGPSFDTI 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 419 SASGLNAALAHYSPTkelHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVfPAATS 498
Cdd:COG0006 131 VASGENAAIPHYTPT---DRPLKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDEQREIYEAVLEAQEAAIAAL-KPGVT 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 499 GRMVEAFARKALWDVGL--NYGHGTGHGIGnfLCVHEWPVGFQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVALVVEA 576
Cdd:COG0006 207 GGEVDAAARDVLAEAGYgeYFPHGTGHGVG--LDVHEGPQISPGNDRPLEPGMVFTIEPGIYIPGIGGVRIEDTVLVTED 284
|
....*....
gi 2148433572 577 K----TKYP 581
Cdd:COG0006 285 GaevlTRLP 293
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
363-575 |
1.33e-48 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 169.34 E-value: 1.33e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 363 LLRASHVRDAVAVIRYLVWLEKNVpqgtvDEFSGAEQLEKLRGEEEFFSGSSFETISASGLNAALAHYSPTKelhRKLSS 442
Cdd:pfam00557 2 LMRKAARIAAAALEAALAAIRPGV-----TERELAAELEAARLRRGGARGPAFPPIVASGPNAAIPHYIPND---RVLKP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 443 DEIYLVDSGGQYWDG-TTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVFPAATsGRMVEAFARKALWDVGL--NYGH 519
Cdd:pfam00557 74 GDLVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVT-GGDVDAAAREVLEEAGLgeYFPH 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2148433572 520 GTGHGIGnfLCVHEWP-VGFQSSNIAMAKGMFTSIEPGYY-LDGEFGIRLEDVALVVE 575
Cdd:pfam00557 153 GLGHGIG--LEVHEGPyISRGGDDRVLEPGMVFTIEPGIYfIPGWGGVRIEDTVLVTE 208
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
411-575 |
2.51e-35 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 132.63 E-value: 2.51e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 411 SGSSFETISASGLNAALAHYSPTKelhRKLSSDEIYLVDSGGqYWDG-TTDVTRTVHWGTPSAFQKEAYTRVLIGN---I 486
Cdd:cd01092 45 EGPSFDTIVASGPNSALPHGVPSD---RKIEEGDLVLIDFGA-IYDGyCSDITRTVAVGEPSDELKEIYEIVLEAQqaaI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 487 DLSRlvfPAATsGRMVEAFARKALWDVGL--NYGHGTGHGIGnfLCVHEWPVGFQSSNIAMAKGMFTSIEPGYYLDGEFG 564
Cdd:cd01092 121 KAVK---PGVT-AKEVDKAARDVIEEAGYgeYFIHRTGHGVG--LEVHEAPYISPGSDDVLEEGMVFTIEPGIYIPGKGG 194
|
170
....*....|.
gi 2148433572 565 IRLEDVALVVE 575
Cdd:cd01092 195 VRIEDDVLVTE 205
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
414-578 |
1.68e-28 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 113.32 E-value: 1.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 414 SFETISASGLNAALAHYSPTkelHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVF 493
Cdd:cd01066 47 AGPTIVGSGARTALPHYRPD---DRRLQEGDLVLVDLGGVYDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALAALR 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 494 PAATsGRMVEAFARKAL--WDVGLNYGHGTGHGIGnfLCVHEWPVGFQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVA 571
Cdd:cd01066 124 PGVT-AEEVDAAAREVLeeHGLGPNFGHRTGHGIG--LEIHEPPVLKAGDDTVLEPGMVFAVEPGLYLPGGGGVRIEDTV 200
|
....*..
gi 2148433572 572 LVVEAKT 578
Cdd:cd01066 201 LVTEDGP 207
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
583-647 |
4.19e-23 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 92.86 E-value: 4.19e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2148433572 583 TYLTFEVVSLVPYDRNLIDVSLLSPEQLQYLNRYYQIIREKVGPELQRRqlQEEFSWLQRHTEPL 647
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEE--EDALEWLKRATRPI 63
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
397-575 |
1.14e-16 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 82.29 E-value: 1.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 397 AEQLE---KLRGEEEffsgSSFETISASGLNAALAHyspTKELHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWGTPSAF 473
Cdd:PRK09795 164 AAELEwfmRQQGAEK----ASFDTIVASGWRGALPH---GKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVS 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 474 QKE-----AYTRVLIGNIDLSRLVFPAaTSGRMVEAFARKALWDVGLN--YGHGTGHGIGnfLCVHEWPVGFQSSNIAMA 546
Cdd:PRK09795 237 AEShplfnVYQIVLQAQLAAISAIRPG-VRCQQVDDAARRVITEAGYGdyFGHNTGHAIG--IEVHEDPRFSPRDTTTLQ 313
|
170 180
....*....|....*....|....*....
gi 2148433572 547 KGMFTSIEPGYYLDGEFGIRLEDVALVVE 575
Cdd:PRK09795 314 PGMLLTVEPGIYLPGQGGVRIEDVVLVTP 342
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
52-183 |
1.20e-14 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 70.80 E-value: 1.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 52 RLTALRQQMYTQNLSAYIVPDTDahmseyigeydqRRAWITGFTGSAGVA-VVTMGKASLWTD-SRYWTQAeRQMDCNWE 129
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTSPE------------NLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAA-AESAPDFD 67
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2148433572 130 LHKEVGTTPIVTWLLTEIPVGARVGVDPFLFSINSWESYDKALqdSDRELVSIT 183
Cdd:pfam01321 68 VVPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEAL--PGAELVDVS 119
|
|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
414-575 |
8.29e-14 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 71.45 E-value: 8.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 414 SFETISASGLNAALAHYSptkELHRKLSSDEIYLVDSGGQYWDGTTDVTRTvhW---GTPSAFQKEAYTRVLIGNIDLSR 490
Cdd:cd01087 47 AYSYIVAAGSNAAILHYV---HNDQPLKDGDLVLIDAGAEYGGYASDITRT--FpvnGKFTDEQRELYEAVLAAQKAAIA 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 491 LVFPAATSGRMVEAFAR---KALWDVGLNYG----------------HGTGHGIGnfLCVHEWPVGFQSS--NIAMAKGM 549
Cdd:cd01087 122 ACKPGVSYEDIHLLAHRvlaEGLKELGILKGdvdeivesgayakffpHGLGHYLG--LDVHDVGGYLRYLrrARPLEPGM 199
|
170 180 190
....*....|....*....|....*....|....*.
gi 2148433572 550 FTSIEPGYYLDGEF----------GIRLEDVALVVE 575
Cdd:cd01087 200 VITIEPGIYFIPDLldvpeyfrggGIRIEDDVLVTE 235
|
|
| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
414-576 |
1.73e-06 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 50.88 E-value: 1.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 414 SFETISASGLNAALAHYSptkELHRKLSSDEIYLVDSGGQYWDGTTDVTRT--VHwGTPSAFQKEAYTRVLiGNIDLSRL 491
Cdd:PRK10879 226 SYNTIVGSGENGCILHYT---ENESEMRDGDLVLIDAGCEYKGYAGDITRTfpVN-GKFTPAQREIYDIVL-ESLETSLR 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 492 VFPAATSGRMV-EAFAR---KALWDVGLNYG----------------HGTGHGIGnfLCVHEwpVGF--QSSNIAMAKGM 549
Cdd:PRK10879 301 LYRPGTSIREVtGEVVRimvSGLVKLGILKGdvdqliaenahrpffmHGLSHWLG--LDVHD--VGVygQDRSRILEPGM 376
|
170 180 190
....*....|....*....|....*....|....*.
gi 2148433572 550 FTSIEPGYYL--DGE-------FGIRLEDVALVVEA 576
Cdd:PRK10879 377 VLTVEPGLYIapDADvpeqyrgIGIRIEDDIVITET 412
|
|
| PRK15173 |
PRK15173 |
peptidase; Provisional |
390-587 |
3.02e-04 |
|
peptidase; Provisional
Pssm-ID: 185095 [Multi-domain] Cd Length: 323 Bit Score: 43.55 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 390 TVDEFSGAEQLEKLRGEEEFFSgsSFETISASglnaalAHYSPTK-ELHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWG 468
Cdd:PRK15173 127 TSAELTAAYKAAVMSKSETHFS--RFHLISVG------ADFSPKLiPSNTKACSGDLIKFDCGVDVDGYGADIARTFVVG 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 469 TPSAFQKEAYTRVLIGNIDLSRLVFPAAtsgRMVEAF--ARKALWDVGL-NYGHG-TGHGIGNFLCVHEWPVGFQSSNIA 544
Cdd:PRK15173 199 EPPEITRKIYQTIRTGHEHMLSMVAPGV---KMKDVFdsTMEVIKKSGLpNYNRGhLGHGNGVFLGLEESPFVSTHATES 275
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2148433572 545 MAKGMFTSIEPGYYLDGEFGIRLEDVALV----VEAKTKYPGTYLTF 587
Cdd:PRK15173 276 FTSGMVLSLETPYYGYNLGSIMIEDMILInkegIEFLSKLPRDLVSF 322
|
|
| PRK14575 |
PRK14575 |
putative peptidase; Provisional |
390-587 |
4.99e-04 |
|
putative peptidase; Provisional
Pssm-ID: 173039 [Multi-domain] Cd Length: 406 Bit Score: 43.16 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 390 TVDEFSGAEQLEKLRGEEEFFSgsSFETISASglnaalAHYSPTK-ELHRKLSSDEIYLVDSGGQYWDGTTDVTRTVHWG 468
Cdd:PRK14575 210 TSAELTAAYKAAVMSKSETHFS--RFHLISVG------ADFSPKLiPSNTKACSGDLIKFDCGVDVDGYGADIARTFVVG 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 469 TPSAFQKEAYTRVLIGNIDLSRLVFPAAtsgRMVEAF--ARKALWDVGL-NYGHG-TGHGIGNFLCVHEWPVGFQSSNIA 544
Cdd:PRK14575 282 EPPEITRKIYQTIRTGHEHMLSMVAPGV---KMKDVFdsTMEVIKKSGLpNYNRGhLGHGNGVFLGLEESPFVSTHATES 358
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2148433572 545 MAKGMFTSIEPGYYLDGEFGIRLEDVALV----VEAKTKYPGTYLTF 587
Cdd:PRK14575 359 FTSGMVLSLETPYYGYNLGSIMIEDMILInkegIEFLSKLPRDLVSF 405
|
|
| PRK14576 |
PRK14576 |
putative endopeptidase; Provisional |
460-575 |
3.03e-03 |
|
putative endopeptidase; Provisional
Pssm-ID: 173040 [Multi-domain] Cd Length: 405 Bit Score: 40.38 E-value: 3.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2148433572 460 DVTRTVHWGTPSAFQKEAYTRVLIGNIDLSRLVFPAATSGRMVEAfARKALWDVGL---NYGHgTGHGIGNFLCVHEWPV 536
Cdd:PRK14576 272 DLARTFVLGEPDKLTQQIYDTIRTGHEHMLSMVAPGVKLKAVFDS-TMAVIKTSGLphyNRGH-LGHGDGVFLGLEEVPF 349
|
90 100 110
....*....|....*....|....*....|....*....
gi 2148433572 537 GFQSSNIAMAKGMFTSIEPGYYLDGEFGIRLEDVALVVE 575
Cdd:PRK14576 350 VSTQATETFCPGMVLSLETPYYGIGVGSIMLEDMILITD 388
|
|
| |
