NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|552848129|ref|XP_005852031|]
View 

hypothetical protein CHLNCDRAFT_132994 [Chlorella variabilis]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 10045852)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

CATH:  2.60.40.10
Gene Ontology:  GO:0005515
PubMed:  19576999|9837732|8981327

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 34-127 3.67e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.11  E-value: 3.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129  34 PKPKALSAAATSDTAVSLTWQA-GDGGSPATcgGYLIAIFKDGQPAGSG-KSFASSVPAAIISGLSRGATYTVQVRALSR 111
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPpEDDGGPIT--GYVVEYREKGSGDWKEvEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                         90
                 ....*....|....*.
gi 552848129 112 LGLaaSEPAQLTGVAT 127
Cdd:cd00063   80 GGE--SPPSESVTVTT 93
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 34-127 3.67e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.11  E-value: 3.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129  34 PKPKALSAAATSDTAVSLTWQA-GDGGSPATcgGYLIAIFKDGQPAGSG-KSFASSVPAAIISGLSRGATYTVQVRALSR 111
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPpEDDGGPIT--GYVVEYREKGSGDWKEvEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                         90
                 ....*....|....*.
gi 552848129 112 LGLaaSEPAQLTGVAT 127
Cdd:cd00063   80 GGE--SPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 34-113 1.31e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 45.30  E-value: 1.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129    34 PKPKALSAAATSDTAVSLTWQAGDGGSPatcGGYLIAIFKDGQPAGSGKSFASSVPA---AIISGLSRGATYTVQVRALS 110
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPPPDDGI---TGYIVGYRVEYREEGSEWKEVNVTPSstsYTLTGLKPGTEYEFRVRAVN 78


                   ...
gi 552848129   111 RLG 113
Cdd:smart00060  79 GAG 81
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
34-171 1.34e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 48.85  E-value: 1.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129  34 PKPKALSAAATSDTAVSLTWQAGDGGSPAtcgGYLI--AIFKDGQPAGSGKSfaSSVPAAIISGLSRGATYTVQVRALSR 111
Cdd:COG3401  328 AAPSGLTATAVGSSSITLSWTASSDADVT---GYNVyrSTSGGGTYTKIAET--VTTTSYTDTGLTPGTTYYYKVTAVDA 402

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 552848129 112 LGL--AASEPAQLTGVATSVPSPAASSAAAGASGSAAEDAWACVAAQGYPVCAAGSAGLCTP 171
Cdd:COG3401  403 AGNesAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDT 464
fn3 pfam00041
Fibronectin type III domain;
34-113 6.51e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.17  E-value: 6.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129   34 PKPKALSAAATSDTAVSLTWQAG-DGGSPATcgGYLIAIFKDGQPaGSGKSF--ASSVPAAIISGLSRGATYTVQVRALS 110
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPpDGNGPIT--GYEVEYRPKNSG-EPWNEItvPGTTTSVTLTGLKPGTEYEVRVQAVN 77


                  ...
gi 552848129  111 RLG 113
Cdd:pfam00041  78 GGG 80
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 34-127 3.67e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.11  E-value: 3.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129  34 PKPKALSAAATSDTAVSLTWQA-GDGGSPATcgGYLIAIFKDGQPAGSG-KSFASSVPAAIISGLSRGATYTVQVRALSR 111
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPpEDDGGPIT--GYVVEYREKGSGDWKEvEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                         90
                 ....*....|....*.
gi 552848129 112 LGLaaSEPAQLTGVAT 127
Cdd:cd00063   80 GGE--SPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 34-113 1.31e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 45.30  E-value: 1.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129    34 PKPKALSAAATSDTAVSLTWQAGDGGSPatcGGYLIAIFKDGQPAGSGKSFASSVPA---AIISGLSRGATYTVQVRALS 110
Cdd:smart00060   2 SPPSNLRVTDVTSTSVTLSWEPPPDDGI---TGYIVGYRVEYREEGSEWKEVNVTPSstsYTLTGLKPGTEYEFRVRAVN 78


                   ...
gi 552848129   111 RLG 113
Cdd:smart00060  79 GAG 81
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
34-171 1.34e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 48.85  E-value: 1.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129  34 PKPKALSAAATSDTAVSLTWQAGDGGSPAtcgGYLI--AIFKDGQPAGSGKSfaSSVPAAIISGLSRGATYTVQVRALSR 111
Cdd:COG3401  328 AAPSGLTATAVGSSSITLSWTASSDADVT---GYNVyrSTSGGGTYTKIAET--VTTTSYTDTGLTPGTTYYYKVTAVDA 402

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 552848129 112 LGL--AASEPAQLTGVATSVPSPAASSAAAGASGSAAEDAWACVAAQGYPVCAAGSAGLCTP 171
Cdd:COG3401  403 AGNesAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDT 464
fn3 pfam00041
Fibronectin type III domain;
34-113 6.51e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.17  E-value: 6.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129   34 PKPKALSAAATSDTAVSLTWQAG-DGGSPATcgGYLIAIFKDGQPaGSGKSF--ASSVPAAIISGLSRGATYTVQVRALS 110
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPpDGNGPIT--GYEVEYRPKNSG-EPWNEItvPGTTTSVTLTGLKPGTEYEVRVQAVN 77


                  ...
gi 552848129  111 RLG 113
Cdd:pfam00041  78 GGG 80
SusE pfam14292
SusE outer membrane protein; This family includes the SusE outer membrane protein from ...
 39-122 5.07e-05

SusE outer membrane protein; This family includes the SusE outer membrane protein from Bacteroides thetaiotaomicron. This protein has a role in starch utilization, but is not essential for growth on starch.


Pssm-ID: 433843  Cd Length: 106  Bit Score: 41.22  E-value: 5.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129   39 LSAAATSDTAVSLTWQAGDGGSPAtcggyliAIFKDGQPAGSGKSFASsvPAAIISGLSRGATYTVQV--RALSRLGLAA 116
Cdd:pfam14292  25 LDLENASADAVTFTWTAADYGYPA-------AVTYTVQFDKDGGDFSS--PVDLGGTTSTSLSITVEElnTLLLNLGLEP 95


                  ....*.
gi 552848129  117 SEPAQL 122
Cdd:pfam14292  96 GETGEL 101
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
36-108 3.27e-04

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 41.30  E-value: 3.27e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 552848129  36 PKALSAAATSDTAVSLTWQAgdggSPATCGGYLIAIFKDGQPAGSgksfASSVPAAIISGLSRGATYTVQVRA 108
Cdd:COG3979    6 PTGLTASNVTSSSVSLSWDA----STDNVGVTGYDVYRGGDQVAT----VTGLTAWTVTGLTPGTEYTFTVGA 70
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
35-123 2.86e-03

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 38.83  E-value: 2.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552848129  35 KPKALSAAATSDTAVSLTWQAGDGGSpATcgGYliAIFKDGQPAGSGKSFAS-SVPAAIISGLSRGATYTVQVRALSRLG 113
Cdd:COG3401  235 APTGLTATADTPGSVTLSWDPVTESD-AT--GY--RVYRSNSGDGPFTKVATvTTTSYTDTGLTNGTTYYYRVTAVDAAG 309

                         90
                 ....*....|..
gi 552848129 114 L--AASEPAQLT 123
Cdd:COG3401  310 NesAPSNVVSVT 321
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH