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hypothetical protein CHLNCDRAFT_57427 [Chlorella variabilis]
Protein Classification
2-oxoglutarate dehydrogenase component E1 family protein ( domain architecture ID 1562477 )
2-oxoglutarate dehydrogenase component E1 family protein may catalyzes the decarboxylation of 2-oxoglutarate and the formation of TPP-hydroxysuccinate or the conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2).
List of domain hits
Name
Accession
Description
Interval
E-value
SucA super family
cl43187 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes ...
41-839
0e+00
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes is part of the Pathway/BioSystem: TCA cycle
COG0567 :Pssm-ID: 440333 [Multi-domain]
Cd Length: 935
Bit Score: 1020.39
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 41 LKD SFL D G TSST Y L EEL E E R Y RAN P R SVD K SW AS FF HSMDMG ----- VPAESVA E AYDAFERGEVTSPLT AAA IS n QTIQ 115
Cdd:COG0567 7 DRS SFL S G ANAA Y I EEL Y E Q Y LED P D SVD P SW RA FF DGLPDV pgard FAHSPIR E EFRKLAKNGAGAAAS AAA DP - EAAR 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 116 ESM R L L LMVR A FQ V M GH YA A Q LDPLG ID ERP R V K ELDPA Y YG F TE K DL NRE F YL G twnke GFM ae G RQVR TL G EI LDR L R 195
Cdd:COG0567 86 KQV R V L QLIN A YR V R GH LF A K LDPLG LR ERP Y V P ELDPA F YG L TE A DL DTV F NT G ----- SLL -- G LETA TL R EI IAA L K 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 196 ETYC S SIG Y EYMHI P D S E RCN W LRA R I E TAE - R QEY S Q EEK L RIL DR LT WS E M FE S FL AN KY TAA KRF G LEG C E A LIP GM 274
Cdd:COG0567 159 ETYC G SIG V EYMHI S D P E EKR W IQE R L E STR n R PSF S A EEK K RIL EK LT AA E G FE K FL HT KY VGQ KRF S LEG G E S LIP AL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 275 KA LI DS A ADQ GV SSV VIGM P HRGRLNVL A N VMR KP MEAV FSEF A G RKP skggdtsg DTYM GSGDVKYHLG T S Y D RP T --- 351
Cdd:COG0567 239 DE LI ER A GEL GV KEI VIGM A HRGRLNVL V N ILG KP PRDI FSEF E G KSA -------- EDVL GSGDVKYHLG F S S D VE T pgg 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 352 ------------------------------------------------- IS GQG I VYE S L D MSQL PD Y TV GGTIH L V V -- 380
Cdd:COG0567 311 kvhlslafnpshleivnpvvegsvrarqdrrgdtdrdkvlpilihgdaa FA GQG V VYE T L N MSQL RG Y RT GGTIH I V I nn 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 381 -- A FTT D P KKS RSS P YCTDVAK ALAC P V FHVN A DD A EAVV R V FE LA AEW RQ TWHG DVVIDL IG YRR Y GHNE I DEP M FTQP 458
Cdd:COG0567 391 qi G FTT S P RDA RSS T YCTDVAK MVQA P I FHVN G DD P EAVV F V AR LA LDY RQ KFKK DVVIDL VC YRR H GHNE G DEP A FTQP 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 459 I MY QA IK R H KNALQV Y QE KL LKD G S I SKDQIRQIA D KVQKQ L HDA FE GA KEYKP K K G DWL SSY W AGF - MSPHQHSRIRN T 537
Cdd:COG0567 471 L MY KK IK K H PTTREI Y AD KL VAE G V I TAEEADEMV D EYRAA L DEG FE VV KEYKP N K A DWL EGD W SPY r RLGEDWDDPVD T 550
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 538 GVP V E L L R E V G YAI T R LPEGF TP H RQIA K VY E A RR H M VDSGEG LDWGMAEALA FGT LL A EG ------------------- 598
Cdd:COG0567 551 GVP L E K L K E L G EKL T T LPEGF KL H PKVE K IL E D RR K M AEGEKP LDWGMAEALA YAS LL D EG ypvrlsgqdsgrgtfshrh 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 599 --------------- NH I -------------------------------------------------- IF DQF V SSGE A K 613
Cdd:COG0567 631 avlhdqktgetyvpl NH L segqarfevynsllseeavlgfeygyalaepntlviweaqfgdfangaqv VI DQF I SSGE S K 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 614 W L R QT GL TV LLPHGY D GQGPEHSSAR M ERFLQ MVD ED pyqlptideskwfigghlgsqiqsc N W QV V N C TTPA N YFH V LR 693
Cdd:COG0567 711 W G R LS GL VM LLPHGY E GQGPEHSSAR L ERFLQ LCA ED ------------------------- N M QV C N P TTPA Q YFH L LR 765
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 694 RQ LH R Q FRKPLI LFA PK N LLRH P LA K S P L A E FS E S aldkdiqgv R F KR VI m D ES stdrsf D PPKQEGF KR M V F CSGKV -- 771
Cdd:COG0567 766 RQ MK R P FRKPLI VMT PK S LLRH K LA V S S L E E LA E G --------- S F QE VI - D DT ------ D ELDPKKV KR V V L CSGKV yy 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ------------------------------------------- M W T QEEP M NMGA YLHV Q P R FQRCMEAMG R evpma VK Y 808
Cdd:COG0567 830 dlleerrergrddvaivrieqlypfpeeelaaelakypnakev V W C QEEP K NMGA WYFI Q H R LEEVLPKGQ R ----- LR Y 904
970 980 990
....*....|....*....|....*....|.
gi 552837515 809 S GRP SM AS T ATG FGE VH AQ EQ AD L INK AL DL 839
Cdd:COG0567 905 A GRP AS AS P ATG YMS VH KA EQ KA L VEE AL GI 935
Name
Accession
Description
Interval
E-value
SucA
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes ...
41-839
0e+00
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440333 [Multi-domain]
Cd Length: 935
Bit Score: 1020.39
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 41 LKD SFL D G TSST Y L EEL E E R Y RAN P R SVD K SW AS FF HSMDMG ----- VPAESVA E AYDAFERGEVTSPLT AAA IS n QTIQ 115
Cdd:COG0567 7 DRS SFL S G ANAA Y I EEL Y E Q Y LED P D SVD P SW RA FF DGLPDV pgard FAHSPIR E EFRKLAKNGAGAAAS AAA DP - EAAR 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 116 ESM R L L LMVR A FQ V M GH YA A Q LDPLG ID ERP R V K ELDPA Y YG F TE K DL NRE F YL G twnke GFM ae G RQVR TL G EI LDR L R 195
Cdd:COG0567 86 KQV R V L QLIN A YR V R GH LF A K LDPLG LR ERP Y V P ELDPA F YG L TE A DL DTV F NT G ----- SLL -- G LETA TL R EI IAA L K 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 196 ETYC S SIG Y EYMHI P D S E RCN W LRA R I E TAE - R QEY S Q EEK L RIL DR LT WS E M FE S FL AN KY TAA KRF G LEG C E A LIP GM 274
Cdd:COG0567 159 ETYC G SIG V EYMHI S D P E EKR W IQE R L E STR n R PSF S A EEK K RIL EK LT AA E G FE K FL HT KY VGQ KRF S LEG G E S LIP AL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 275 KA LI DS A ADQ GV SSV VIGM P HRGRLNVL A N VMR KP MEAV FSEF A G RKP skggdtsg DTYM GSGDVKYHLG T S Y D RP T --- 351
Cdd:COG0567 239 DE LI ER A GEL GV KEI VIGM A HRGRLNVL V N ILG KP PRDI FSEF E G KSA -------- EDVL GSGDVKYHLG F S S D VE T pgg 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 352 ------------------------------------------------- IS GQG I VYE S L D MSQL PD Y TV GGTIH L V V -- 380
Cdd:COG0567 311 kvhlslafnpshleivnpvvegsvrarqdrrgdtdrdkvlpilihgdaa FA GQG V VYE T L N MSQL RG Y RT GGTIH I V I nn 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 381 -- A FTT D P KKS RSS P YCTDVAK ALAC P V FHVN A DD A EAVV R V FE LA AEW RQ TWHG DVVIDL IG YRR Y GHNE I DEP M FTQP 458
Cdd:COG0567 391 qi G FTT S P RDA RSS T YCTDVAK MVQA P I FHVN G DD P EAVV F V AR LA LDY RQ KFKK DVVIDL VC YRR H GHNE G DEP A FTQP 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 459 I MY QA IK R H KNALQV Y QE KL LKD G S I SKDQIRQIA D KVQKQ L HDA FE GA KEYKP K K G DWL SSY W AGF - MSPHQHSRIRN T 537
Cdd:COG0567 471 L MY KK IK K H PTTREI Y AD KL VAE G V I TAEEADEMV D EYRAA L DEG FE VV KEYKP N K A DWL EGD W SPY r RLGEDWDDPVD T 550
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 538 GVP V E L L R E V G YAI T R LPEGF TP H RQIA K VY E A RR H M VDSGEG LDWGMAEALA FGT LL A EG ------------------- 598
Cdd:COG0567 551 GVP L E K L K E L G EKL T T LPEGF KL H PKVE K IL E D RR K M AEGEKP LDWGMAEALA YAS LL D EG ypvrlsgqdsgrgtfshrh 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 599 --------------- NH I -------------------------------------------------- IF DQF V SSGE A K 613
Cdd:COG0567 631 avlhdqktgetyvpl NH L segqarfevynsllseeavlgfeygyalaepntlviweaqfgdfangaqv VI DQF I SSGE S K 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 614 W L R QT GL TV LLPHGY D GQGPEHSSAR M ERFLQ MVD ED pyqlptideskwfigghlgsqiqsc N W QV V N C TTPA N YFH V LR 693
Cdd:COG0567 711 W G R LS GL VM LLPHGY E GQGPEHSSAR L ERFLQ LCA ED ------------------------- N M QV C N P TTPA Q YFH L LR 765
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 694 RQ LH R Q FRKPLI LFA PK N LLRH P LA K S P L A E FS E S aldkdiqgv R F KR VI m D ES stdrsf D PPKQEGF KR M V F CSGKV -- 771
Cdd:COG0567 766 RQ MK R P FRKPLI VMT PK S LLRH K LA V S S L E E LA E G --------- S F QE VI - D DT ------ D ELDPKKV KR V V L CSGKV yy 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ------------------------------------------- M W T QEEP M NMGA YLHV Q P R FQRCMEAMG R evpma VK Y 808
Cdd:COG0567 830 dlleerrergrddvaivrieqlypfpeeelaaelakypnakev V W C QEEP K NMGA WYFI Q H R LEEVLPKGQ R ----- LR Y 904
970 980 990
....*....|....*....|....*....|.
gi 552837515 809 S GRP SM AS T ATG FGE VH AQ EQ AD L INK AL DL 839
Cdd:COG0567 905 A GRP AS AS P ATG YMS VH KA EQ KA L VEE AL GI 935
sucA
PRK09404 2-oxoglutarate dehydrogenase E1 component; Reviewed
41-838
0e+00
2-oxoglutarate dehydrogenase E1 component; Reviewed
Pssm-ID: 236499 [Multi-domain]
Cd Length: 924
Bit Score: 987.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 41 L KD SFL D G TSST Y L EEL E E R Y RAN P R SVD KS W AS FF HSMDMGV P AESVAEAYDA F E R gevts PLTA A AI S NQTIQESMRL 120
Cdd:PRK09404 9 L DS SFL F G ANAA Y I EEL Y E Q Y LKD P D SVD EE W RA FF DGLPGVA P DVAHSAVRES F R R ----- LAKP A RV S SAVSDPQVKV 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 121 L LMVR A FQVM GH Y AA Q LDPLG IDE RP R V K ELDPA Y YG F TE K DL N R E F YL G TWNK egfmae G RQVR TL G EI LDR L RE TYC S 200
Cdd:PRK09404 84 L QLIN A YRFR GH L AA N LDPLG LWK RP D V P ELDPA F YG L TE A DL D R T F NT G SLAL ------ G KETA TL R EI IEA L KK TYC G 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 201 SIG Y EYMHI P D S E RCN WL RA RIE T a E R QEY S Q EEK LR IL D RLT WS E M FE S FL AN K YTAA KRF G LEG C E A LIP GMKAL I DS 280
Cdd:PRK09404 158 SIG V EYMHI S D P E ERR WL QQ RIE S - G R PSF S A EEK KA IL E RLT AA E G FE R FL HT K FVGQ KRF S LEG G E S LIP MLDEI I RR 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 281 A ADQ GV SSV VIGM P HRGRLNVL A NV MR KP MEAV F S EF A G RKPSKG gdtsgdt YM GSGDVKYHLG T S Y DR P T --------- 351
Cdd:PRK09404 237 A GKL GV KEI VIGM A HRGRLNVL V NV LG KP PRDL F A EF E G KHGPDE ------- VL GSGDVKYHLG F S S DR E T dggevhlsl 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 352 -------------------------------------------- IS GQG I V Y E S L DM SQL PD Y TV GGTIH L V V ---- A FT 383
Cdd:PRK09404 310 afnpshleivnpvvegsvrarqdrrgdgqdrkkvlpilihgdaa FA GQG V V A E T L NL SQL RG Y RT GGTIH I V I nnqi G FT 389
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 384 T D P KKS RS S PYCTDVAK ALAC P V FHVN A DD A EAVV RVFE LA A E W RQ TWHG DVVIDL IG YRR Y GHNE I DEP M FTQP I MY QA 463
Cdd:PRK09404 390 T S P PDD RS T PYCTDVAK MVQA P I FHVN G DD P EAVV FATR LA L E Y RQ KFKK DVVIDL VC YRR H GHNE G DEP S FTQP L MY KK 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 464 IK R H KNALQV Y QE KL LKD G S I SKDQIRQIADKVQKQ L HDA FE GA KE YK P K kg DWL SSY W AGFM s P H QHSRIRN TGVP V E L 543
Cdd:PRK09404 470 IK K H PTTREL Y AD KL VAE G V I TEEEADEMVNEYRDA L DAG FE VV KE WR P A -- DWL AGD W SPYL - G H EWDDPVD TGVP L E R 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 544 L R E VGYAI T RL PEGF TP H RQIA K VY E A RR H M VDSGEGL DWGMAEALAF GT LL A EG ------------------------- 598
Cdd:PRK09404 547 L K E LAEKL T TV PEGF KV H PKVK K IL E D RR E M AEGEKPI DWGMAEALAF AS LL D EG ypvrlsgqdsgrgtfshrhavlhdq 626
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 599 --------- NH I -------------------------------------------------- IF DQF V SSGE A KW L R QT G 619
Cdd:PRK09404 627 ktgetyipl NH L segqasfevydsplseeavlgfeygystaepntlviweaqfgdfangaqv VI DQF I SSGE Q KW G R LS G 706
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 620 L TV LLPHGY D GQGPEHSSAR M ERFLQ MVD ED pyqlptideskwfigghlgsqiqsc N W QV V N C TTPA N YFH V LRRQ LH R Q 699
Cdd:PRK09404 707 L VM LLPHGY E GQGPEHSSAR L ERFLQ LCA ED ------------------------- N M QV C N P TTPA Q YFH L LRRQ AL R P 761
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 700 FRKPL ILFA PK N LLRHPLA K S P L A E FS E S aldkdiqgv R F KR VI M D ESST D R sfdppkq EGF KR M V F CSGKV -------- 771
Cdd:PRK09404 762 FRKPL VVMT PK S LLRHPLA V S S L E E LA E G --------- S F QP VI G D IDEL D P ------- KKV KR V V L CSGKV yydllear 825
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ------------------------------------- M W T QEEP M N M GA YLHV Q PRFQRCMEAMGR evpma VK Y S GRP SM 814
Cdd:PRK09404 826 rkrgiddvaivrieqlypfpheelaaelakypnakev V W C QEEP K N Q GA WYFI Q HHLEEVLPEGQK ----- LR Y A GRP AS 900
970 980
....*....|....*....|....
gi 552837515 815 AS T A T G FGEV H AQE Q AD L INK AL D 838
Cdd:PRK09404 901 AS P A V G YMSL H KKQ Q EA L VED AL G 924
2oxo_dh_E1
TIGR00239 2-oxoglutarate dehydrogenase, E1 component; The 2-oxoglutarate dehydrogenase complex consists ...
45-837
0e+00
2-oxoglutarate dehydrogenase, E1 component; The 2-oxoglutarate dehydrogenase complex consists of this thiamine pyrophosphate-binding subunit (E1), dihydrolipoamide succinyltransferase (E2), and lipoamide dehydrogenase (E3). The E1 ortholog from Corynebacterium glutamicum is unusual in having an N-terminal extension that resembles the dihydrolipoamide succinyltransferase (E2) component of 2-oxoglutarate dehydrogenase. [Energy metabolism, TCA cycle]
Pssm-ID: 161785 [Multi-domain]
Cd Length: 929
Bit Score: 737.83
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 45 F L D G TSST Y L EEL E E R Y RAN P R SVD K SW A S F F HSMDMGV PA ESV -- AEAYDA F E R GEVTSPL - TAAAISNQ T IQESMRL L 121
Cdd:TIGR00239 1 Y L S G ANQS Y I EEL Y E D Y LTD P D SVD A SW R S T F DQLPGPG PA PDQ fh SPTRSY F R R LAKDASR g SVTISDPD T NVSQVKV L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 122 LMV RA FQVM GH YA A Q LDPLG IDERPR V K ELD PAY YG F TE K DL NRE F YL G TW -- N K EGF M AEG rqvrt LG E I L DR L RE TYC 199
Cdd:TIGR00239 81 QLI RA YRFR GH LH A N LDPLG LKQQDK V P ELD LSF YG L TE A DL QET F NI G SF vs G K DAT M KLS ----- NL E L L QA L KQ TYC 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 200 S SIG Y EYMHI PDS E RCN WL RA RIE TA ER QEYSQ EEK L R I L D RLT WS E M FE S FL AN K YTA AKRF G LEG CE AL I P GM K AL I D 279
Cdd:TIGR00239 156 G SIG A EYMHI TST E EKR WL QQ RIE SG ER AQFNS EEK K R F L S RLT AA E G FE R FL GA K FPG AKRF S LEG LD AL V P ML K EI I R 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 280 SAADQ G VSS VV I GM P HRGRLNVL A NV MR KP M E AV FSEFAG RKP S kggdtsg DTYM G S GDVKYH L G TSYDRP T IS ------ 353
Cdd:TIGR00239 236 HSVNS G TRD VV L GM A HRGRLNVL V NV LG KP P E DI FSEFAG KHK S ------- HLPD G T GDVKYH M G RFSSDF T TD gklvhl 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 354 ------------------------------------------------ GQG I V Y E S L D MS Q L PD Y T VGGTIH LV ---- VA 381
Cdd:TIGR00239 309 alafnpshleivspvvigstrarldrlndspestkvlailihgdaafa GQG V V Q E T L N MS K L RG Y S VGGTIH II innq IG 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 382 FTT D P KKS RS S PYC T D V AK ALAC P V FHVNADD A EAV VRVFE LA A E W R Q T WHG DV V IDL I GYRR Y GHNE I DEP MF TQP I MY 461
Cdd:TIGR00239 389 FTT N P LDA RS T PYC S D L AK MIQA P I FHVNADD P EAV AFATR LA V E Y R N T FKR DV F IDL V GYRR H GHNE A DEP SA TQP L MY 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 462 Q A IK R H KNALQ VY QE KL LKD G SISKDQIRQIADKVQ kqlh DA F E G A KEYK P KKGDWLSSYWAGFMS - P H QHSRIRNTG V P 540
Cdd:TIGR00239 469 Q K IK K H PTPRK VY AD KL VSE G VATEEDVTEMVNLYR ---- DA L E A A DCVV P SWREMNTASFTWSPE l N H EWDEEYPNK V E 544
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 541 VEL L R E VGYA I TRL PEG FTP H RQI AK V Y EA R RHMVDS GE G L - DWG M AE A LAF G TL LAE G N -------------------- 599
Cdd:TIGR00239 545 MKR L Q E LAKR I SEV PEG VEM H SRV AK I Y FD R TKAMAA GE K L f DWG G AE N LAF A TL VDD G I pvrlsgedsergtffqrhav 624
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 600 ---------------------------------------------------------------- HIIF DQF V SSGE A KW L 615
Cdd:TIGR00239 625 lhdqsngstytplqhlhngqgafrvwnsvlseesvlgfeygyattsprtlviweaqfgdfanga QVVI DQF I SSGE Q KW G 704
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 616 RQT GL TV LLPHGY D GQGPEHSS A R M ERFLQ MVD E D pyqlptideskwfigghlgsqiqsc N W QV VNC TTPA NY FH V LRRQ 695
Cdd:TIGR00239 705 QMS GL VM LLPHGY E GQGPEHSS G R L ERFLQ LAA E Q ------------------------- N M QV CVP TTPA QV FH I LRRQ 759
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 696 LH R QF R K PL ILFA PK N LLRHPLA K S P L A E FS E S aldkdiqgv R F KR VI MDESSTDR S F DP pkq EG F KR M V F CSGKV ---- 771
Cdd:TIGR00239 760 AL R GM R R PL VVMS PK S LLRHPLA V S S L E E LA E G --------- T F QP VI GEIEESGL S L DP --- EG V KR L V L CSGKV yydl 827
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ----------------------------------------- M W T QEEP M NMGA YLHV QP RFQ rcm E AMGRE V pm A V K Y S G 810
Cdd:TIGR00239 828 heqrrkngqkdvaivrieqlypfphkavkevlqqypnlkei V W C QEEP L NMGA WYYS QP HLR --- E VIPEG V -- S V R Y A G 902
970 980
....*....|....*....|....*..
gi 552837515 811 RP SM AS T A T G FGEV H AQE Q A DL I N K AL 837
Cdd:TIGR00239 903 RP AS AS P A V G YMSL H QKQ Q Q DL L N D AL 929
TPP_E1_OGDC_like
cd02016 Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed ...
248-461
1.29e-122
Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of 2-oxoglutarate to succinyl-CoA and carbon dioxide, a key reaction of the tricarboxylic acid cycle.
Pssm-ID: 238974 [Multi-domain]
Cd Length: 265
Bit Score: 369.94
E-value: 1.29e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 248 FE S FLA N K YTAA KRFGLEG C E A LIP GMKA LID S AA DQ GV SS VVIGM P HRGRLNVLANV MR KP M E AV FSEF agrkps K G GD 327
Cdd:cd02016 1 FE Q FLA T K FPGQ KRFGLEG A E S LIP ALDE LID R AA EL GV EE VVIGM A HRGRLNVLANV LG KP L E QI FSEF ------ E G KS 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 328 TSGDTYM GSGDVKYHLG T S Y DR P T ----------------------------------------------------- IS G 354
Cdd:cd02016 75 EFPEDDE GSGDVKYHLG Y S S DR K T psgkkvhlslapnpshleavnpvvmgktrakqdyrgdgerdkvlpilihgdaa FA G 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 355 QG I VYE S L DM S Q LP D YT V GGTIH L VV ---- A FTTDP KK SRSSPYCTDVAK ALAC P V FHVN A DD A EAVVR VFE LA A E W RQ T 430
Cdd:cd02016 155 QG V VYE T L NL S N LP G YT T GGTIH I VV nnqi G FTTDP RD SRSSPYCTDVAK MIGA P I FHVN G DD P EAVVR ATR LA L E Y RQ K 234
250 260 270
....*....|....*....|....*....|.
gi 552837515 431 WHG DVVIDL IG YRR Y GHNE I DEP M FTQP I MY 461
Cdd:cd02016 235 FKK DVVIDL VC YRR H GHNE L DEP S FTQP L MY 265
E1_dh
pfam00676 Dehydrogenase E1 component; This family uses thiamine pyrophosphate as a cofactor. This family ...
248-512
6.32e-45
Dehydrogenase E1 component; This family uses thiamine pyrophosphate as a cofactor. This family includes pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase and 2-oxoisovalerate dehydrogenase.
Pssm-ID: 395548 [Multi-domain]
Cd Length: 300
Bit Score: 163.65
E-value: 6.32e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 248 F E SFLANK Y TAAKRF G LEGCE A LIPGMKAL I DS A ADQ G vs SVV I GM p H R GRL N V LA NVM rk PM E AV F S E FA GR KPS - KGG 326
Cdd:pfam00676 9 M E DARDAL Y KRQGIR G FYHLY A GQEAAQVG I AA A LEP G -- DYI I PG - Y R DHG N L LA RGL -- SL E EI F A E LY GR VAK g KGG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 327 DTS G ------- DT Y M G S G DV kyhl G TSY --------------- DRPT I ------- SG QG IVY E S L DMSQ L PDYT V ggt I H 377
Cdd:pfam00676 84 SMH G yygakgn RF Y G G N G IL ---- G AQV plgagialaakyrgk KEVA I tlygdga AN QG DFF E G L NFAA L WKLP V --- I F 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 378 LVV ---- AFT T DPKKSRS S PYCT D V A KALAC P VF HV NAD D AE AV VRVFEL AAE WRQ T WH G DVV I D L IG YR RY GH NEI D E P 453
Cdd:pfam00676 157 VCE nnqy GIS T PAERASA S TTYA D R A RGYGI P GL HV DGM D PL AV YQASKF AAE RAR T GK G PFL I E L VT YR YG GH SMS D D P 236
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 454 MFTQ - PIM Y QAIKRH K NAL Q VYQ E K L LKD G SI S KDQIRQ I ADK V Q K QLHD AF EG A KEYKP 512
Cdd:pfam00676 237 STYR t RDE Y EEVRKK K DPI Q RFK E H L VSK G VW S EEELKA I EKE V R K EVEE AF KK A ESAPE 296
Name
Accession
Description
Interval
E-value
SucA
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes ...
41-839
0e+00
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440333 [Multi-domain]
Cd Length: 935
Bit Score: 1020.39
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 41 LKD SFL D G TSST Y L EEL E E R Y RAN P R SVD K SW AS FF HSMDMG ----- VPAESVA E AYDAFERGEVTSPLT AAA IS n QTIQ 115
Cdd:COG0567 7 DRS SFL S G ANAA Y I EEL Y E Q Y LED P D SVD P SW RA FF DGLPDV pgard FAHSPIR E EFRKLAKNGAGAAAS AAA DP - EAAR 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 116 ESM R L L LMVR A FQ V M GH YA A Q LDPLG ID ERP R V K ELDPA Y YG F TE K DL NRE F YL G twnke GFM ae G RQVR TL G EI LDR L R 195
Cdd:COG0567 86 KQV R V L QLIN A YR V R GH LF A K LDPLG LR ERP Y V P ELDPA F YG L TE A DL DTV F NT G ----- SLL -- G LETA TL R EI IAA L K 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 196 ETYC S SIG Y EYMHI P D S E RCN W LRA R I E TAE - R QEY S Q EEK L RIL DR LT WS E M FE S FL AN KY TAA KRF G LEG C E A LIP GM 274
Cdd:COG0567 159 ETYC G SIG V EYMHI S D P E EKR W IQE R L E STR n R PSF S A EEK K RIL EK LT AA E G FE K FL HT KY VGQ KRF S LEG G E S LIP AL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 275 KA LI DS A ADQ GV SSV VIGM P HRGRLNVL A N VMR KP MEAV FSEF A G RKP skggdtsg DTYM GSGDVKYHLG T S Y D RP T --- 351
Cdd:COG0567 239 DE LI ER A GEL GV KEI VIGM A HRGRLNVL V N ILG KP PRDI FSEF E G KSA -------- EDVL GSGDVKYHLG F S S D VE T pgg 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 352 ------------------------------------------------- IS GQG I VYE S L D MSQL PD Y TV GGTIH L V V -- 380
Cdd:COG0567 311 kvhlslafnpshleivnpvvegsvrarqdrrgdtdrdkvlpilihgdaa FA GQG V VYE T L N MSQL RG Y RT GGTIH I V I nn 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 381 -- A FTT D P KKS RSS P YCTDVAK ALAC P V FHVN A DD A EAVV R V FE LA AEW RQ TWHG DVVIDL IG YRR Y GHNE I DEP M FTQP 458
Cdd:COG0567 391 qi G FTT S P RDA RSS T YCTDVAK MVQA P I FHVN G DD P EAVV F V AR LA LDY RQ KFKK DVVIDL VC YRR H GHNE G DEP A FTQP 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 459 I MY QA IK R H KNALQV Y QE KL LKD G S I SKDQIRQIA D KVQKQ L HDA FE GA KEYKP K K G DWL SSY W AGF - MSPHQHSRIRN T 537
Cdd:COG0567 471 L MY KK IK K H PTTREI Y AD KL VAE G V I TAEEADEMV D EYRAA L DEG FE VV KEYKP N K A DWL EGD W SPY r RLGEDWDDPVD T 550
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 538 GVP V E L L R E V G YAI T R LPEGF TP H RQIA K VY E A RR H M VDSGEG LDWGMAEALA FGT LL A EG ------------------- 598
Cdd:COG0567 551 GVP L E K L K E L G EKL T T LPEGF KL H PKVE K IL E D RR K M AEGEKP LDWGMAEALA YAS LL D EG ypvrlsgqdsgrgtfshrh 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 599 --------------- NH I -------------------------------------------------- IF DQF V SSGE A K 613
Cdd:COG0567 631 avlhdqktgetyvpl NH L segqarfevynsllseeavlgfeygyalaepntlviweaqfgdfangaqv VI DQF I SSGE S K 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 614 W L R QT GL TV LLPHGY D GQGPEHSSAR M ERFLQ MVD ED pyqlptideskwfigghlgsqiqsc N W QV V N C TTPA N YFH V LR 693
Cdd:COG0567 711 W G R LS GL VM LLPHGY E GQGPEHSSAR L ERFLQ LCA ED ------------------------- N M QV C N P TTPA Q YFH L LR 765
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 694 RQ LH R Q FRKPLI LFA PK N LLRH P LA K S P L A E FS E S aldkdiqgv R F KR VI m D ES stdrsf D PPKQEGF KR M V F CSGKV -- 771
Cdd:COG0567 766 RQ MK R P FRKPLI VMT PK S LLRH K LA V S S L E E LA E G --------- S F QE VI - D DT ------ D ELDPKKV KR V V L CSGKV yy 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ------------------------------------------- M W T QEEP M NMGA YLHV Q P R FQRCMEAMG R evpma VK Y 808
Cdd:COG0567 830 dlleerrergrddvaivrieqlypfpeeelaaelakypnakev V W C QEEP K NMGA WYFI Q H R LEEVLPKGQ R ----- LR Y 904
970 980 990
....*....|....*....|....*....|.
gi 552837515 809 S GRP SM AS T ATG FGE VH AQ EQ AD L INK AL DL 839
Cdd:COG0567 905 A GRP AS AS P ATG YMS VH KA EQ KA L VEE AL GI 935
sucA
PRK09404 2-oxoglutarate dehydrogenase E1 component; Reviewed
41-838
0e+00
2-oxoglutarate dehydrogenase E1 component; Reviewed
Pssm-ID: 236499 [Multi-domain]
Cd Length: 924
Bit Score: 987.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 41 L KD SFL D G TSST Y L EEL E E R Y RAN P R SVD KS W AS FF HSMDMGV P AESVAEAYDA F E R gevts PLTA A AI S NQTIQESMRL 120
Cdd:PRK09404 9 L DS SFL F G ANAA Y I EEL Y E Q Y LKD P D SVD EE W RA FF DGLPGVA P DVAHSAVRES F R R ----- LAKP A RV S SAVSDPQVKV 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 121 L LMVR A FQVM GH Y AA Q LDPLG IDE RP R V K ELDPA Y YG F TE K DL N R E F YL G TWNK egfmae G RQVR TL G EI LDR L RE TYC S 200
Cdd:PRK09404 84 L QLIN A YRFR GH L AA N LDPLG LWK RP D V P ELDPA F YG L TE A DL D R T F NT G SLAL ------ G KETA TL R EI IEA L KK TYC G 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 201 SIG Y EYMHI P D S E RCN WL RA RIE T a E R QEY S Q EEK LR IL D RLT WS E M FE S FL AN K YTAA KRF G LEG C E A LIP GMKAL I DS 280
Cdd:PRK09404 158 SIG V EYMHI S D P E ERR WL QQ RIE S - G R PSF S A EEK KA IL E RLT AA E G FE R FL HT K FVGQ KRF S LEG G E S LIP MLDEI I RR 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 281 A ADQ GV SSV VIGM P HRGRLNVL A NV MR KP MEAV F S EF A G RKPSKG gdtsgdt YM GSGDVKYHLG T S Y DR P T --------- 351
Cdd:PRK09404 237 A GKL GV KEI VIGM A HRGRLNVL V NV LG KP PRDL F A EF E G KHGPDE ------- VL GSGDVKYHLG F S S DR E T dggevhlsl 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 352 -------------------------------------------- IS GQG I V Y E S L DM SQL PD Y TV GGTIH L V V ---- A FT 383
Cdd:PRK09404 310 afnpshleivnpvvegsvrarqdrrgdgqdrkkvlpilihgdaa FA GQG V V A E T L NL SQL RG Y RT GGTIH I V I nnqi G FT 389
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 384 T D P KKS RS S PYCTDVAK ALAC P V FHVN A DD A EAVV RVFE LA A E W RQ TWHG DVVIDL IG YRR Y GHNE I DEP M FTQP I MY QA 463
Cdd:PRK09404 390 T S P PDD RS T PYCTDVAK MVQA P I FHVN G DD P EAVV FATR LA L E Y RQ KFKK DVVIDL VC YRR H GHNE G DEP S FTQP L MY KK 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 464 IK R H KNALQV Y QE KL LKD G S I SKDQIRQIADKVQKQ L HDA FE GA KE YK P K kg DWL SSY W AGFM s P H QHSRIRN TGVP V E L 543
Cdd:PRK09404 470 IK K H PTTREL Y AD KL VAE G V I TEEEADEMVNEYRDA L DAG FE VV KE WR P A -- DWL AGD W SPYL - G H EWDDPVD TGVP L E R 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 544 L R E VGYAI T RL PEGF TP H RQIA K VY E A RR H M VDSGEGL DWGMAEALAF GT LL A EG ------------------------- 598
Cdd:PRK09404 547 L K E LAEKL T TV PEGF KV H PKVK K IL E D RR E M AEGEKPI DWGMAEALAF AS LL D EG ypvrlsgqdsgrgtfshrhavlhdq 626
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 599 --------- NH I -------------------------------------------------- IF DQF V SSGE A KW L R QT G 619
Cdd:PRK09404 627 ktgetyipl NH L segqasfevydsplseeavlgfeygystaepntlviweaqfgdfangaqv VI DQF I SSGE Q KW G R LS G 706
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 620 L TV LLPHGY D GQGPEHSSAR M ERFLQ MVD ED pyqlptideskwfigghlgsqiqsc N W QV V N C TTPA N YFH V LRRQ LH R Q 699
Cdd:PRK09404 707 L VM LLPHGY E GQGPEHSSAR L ERFLQ LCA ED ------------------------- N M QV C N P TTPA Q YFH L LRRQ AL R P 761
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 700 FRKPL ILFA PK N LLRHPLA K S P L A E FS E S aldkdiqgv R F KR VI M D ESST D R sfdppkq EGF KR M V F CSGKV -------- 771
Cdd:PRK09404 762 FRKPL VVMT PK S LLRHPLA V S S L E E LA E G --------- S F QP VI G D IDEL D P ------- KKV KR V V L CSGKV yydllear 825
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ------------------------------------- M W T QEEP M N M GA YLHV Q PRFQRCMEAMGR evpma VK Y S GRP SM 814
Cdd:PRK09404 826 rkrgiddvaivrieqlypfpheelaaelakypnakev V W C QEEP K N Q GA WYFI Q HHLEEVLPEGQK ----- LR Y A GRP AS 900
970 980
....*....|....*....|....
gi 552837515 815 AS T A T G FGEV H AQE Q AD L INK AL D 838
Cdd:PRK09404 901 AS P A V G YMSL H KKQ Q EA L VED AL G 924
2oxo_dh_E1
TIGR00239 2-oxoglutarate dehydrogenase, E1 component; The 2-oxoglutarate dehydrogenase complex consists ...
45-837
0e+00
2-oxoglutarate dehydrogenase, E1 component; The 2-oxoglutarate dehydrogenase complex consists of this thiamine pyrophosphate-binding subunit (E1), dihydrolipoamide succinyltransferase (E2), and lipoamide dehydrogenase (E3). The E1 ortholog from Corynebacterium glutamicum is unusual in having an N-terminal extension that resembles the dihydrolipoamide succinyltransferase (E2) component of 2-oxoglutarate dehydrogenase. [Energy metabolism, TCA cycle]
Pssm-ID: 161785 [Multi-domain]
Cd Length: 929
Bit Score: 737.83
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 45 F L D G TSST Y L EEL E E R Y RAN P R SVD K SW A S F F HSMDMGV PA ESV -- AEAYDA F E R GEVTSPL - TAAAISNQ T IQESMRL L 121
Cdd:TIGR00239 1 Y L S G ANQS Y I EEL Y E D Y LTD P D SVD A SW R S T F DQLPGPG PA PDQ fh SPTRSY F R R LAKDASR g SVTISDPD T NVSQVKV L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 122 LMV RA FQVM GH YA A Q LDPLG IDERPR V K ELD PAY YG F TE K DL NRE F YL G TW -- N K EGF M AEG rqvrt LG E I L DR L RE TYC 199
Cdd:TIGR00239 81 QLI RA YRFR GH LH A N LDPLG LKQQDK V P ELD LSF YG L TE A DL QET F NI G SF vs G K DAT M KLS ----- NL E L L QA L KQ TYC 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 200 S SIG Y EYMHI PDS E RCN WL RA RIE TA ER QEYSQ EEK L R I L D RLT WS E M FE S FL AN K YTA AKRF G LEG CE AL I P GM K AL I D 279
Cdd:TIGR00239 156 G SIG A EYMHI TST E EKR WL QQ RIE SG ER AQFNS EEK K R F L S RLT AA E G FE R FL GA K FPG AKRF S LEG LD AL V P ML K EI I R 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 280 SAADQ G VSS VV I GM P HRGRLNVL A NV MR KP M E AV FSEFAG RKP S kggdtsg DTYM G S GDVKYH L G TSYDRP T IS ------ 353
Cdd:TIGR00239 236 HSVNS G TRD VV L GM A HRGRLNVL V NV LG KP P E DI FSEFAG KHK S ------- HLPD G T GDVKYH M G RFSSDF T TD gklvhl 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 354 ------------------------------------------------ GQG I V Y E S L D MS Q L PD Y T VGGTIH LV ---- VA 381
Cdd:TIGR00239 309 alafnpshleivspvvigstrarldrlndspestkvlailihgdaafa GQG V V Q E T L N MS K L RG Y S VGGTIH II innq IG 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 382 FTT D P KKS RS S PYC T D V AK ALAC P V FHVNADD A EAV VRVFE LA A E W R Q T WHG DV V IDL I GYRR Y GHNE I DEP MF TQP I MY 461
Cdd:TIGR00239 389 FTT N P LDA RS T PYC S D L AK MIQA P I FHVNADD P EAV AFATR LA V E Y R N T FKR DV F IDL V GYRR H GHNE A DEP SA TQP L MY 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 462 Q A IK R H KNALQ VY QE KL LKD G SISKDQIRQIADKVQ kqlh DA F E G A KEYK P KKGDWLSSYWAGFMS - P H QHSRIRNTG V P 540
Cdd:TIGR00239 469 Q K IK K H PTPRK VY AD KL VSE G VATEEDVTEMVNLYR ---- DA L E A A DCVV P SWREMNTASFTWSPE l N H EWDEEYPNK V E 544
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 541 VEL L R E VGYA I TRL PEG FTP H RQI AK V Y EA R RHMVDS GE G L - DWG M AE A LAF G TL LAE G N -------------------- 599
Cdd:TIGR00239 545 MKR L Q E LAKR I SEV PEG VEM H SRV AK I Y FD R TKAMAA GE K L f DWG G AE N LAF A TL VDD G I pvrlsgedsergtffqrhav 624
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 600 ---------------------------------------------------------------- HIIF DQF V SSGE A KW L 615
Cdd:TIGR00239 625 lhdqsngstytplqhlhngqgafrvwnsvlseesvlgfeygyattsprtlviweaqfgdfanga QVVI DQF I SSGE Q KW G 704
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 616 RQT GL TV LLPHGY D GQGPEHSS A R M ERFLQ MVD E D pyqlptideskwfigghlgsqiqsc N W QV VNC TTPA NY FH V LRRQ 695
Cdd:TIGR00239 705 QMS GL VM LLPHGY E GQGPEHSS G R L ERFLQ LAA E Q ------------------------- N M QV CVP TTPA QV FH I LRRQ 759
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 696 LH R QF R K PL ILFA PK N LLRHPLA K S P L A E FS E S aldkdiqgv R F KR VI MDESSTDR S F DP pkq EG F KR M V F CSGKV ---- 771
Cdd:TIGR00239 760 AL R GM R R PL VVMS PK S LLRHPLA V S S L E E LA E G --------- T F QP VI GEIEESGL S L DP --- EG V KR L V L CSGKV yydl 827
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ----------------------------------------- M W T QEEP M NMGA YLHV QP RFQ rcm E AMGRE V pm A V K Y S G 810
Cdd:TIGR00239 828 heqrrkngqkdvaivrieqlypfphkavkevlqqypnlkei V W C QEEP L NMGA WYYS QP HLR --- E VIPEG V -- S V R Y A G 902
970 980
....*....|....*....|....*..
gi 552837515 811 RP SM AS T A T G FGEV H AQE Q A DL I N K AL 837
Cdd:TIGR00239 903 RP AS AS P A V G YMSL H QKQ Q Q DL L N D AL 929
kgd
PRK12270 multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
80-839
0e+00
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain]
Cd Length: 1228
Bit Score: 721.29
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 80 DMGV P A E S V AE A Y D A fergevtsplta A A ISNQTIQESM R LLLMVR A FQ V M GH YA A QL DPL GIDE R p RVKE LD PAYY G F T 159
Cdd:PRK12270 361 SLRI P Y E P V RW A T D I ------------ P A DHEDEVDKNA R VMELIH A YR V R GH LM A DT DPL EYRQ R - SHPD LD VLTH G L T 427
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 160 EK DL N REF YL G twnke GF ma E G RQVRT L GE IL DR LR ET YC SSI G Y EYMHI P D S E RCN WL RA R I E t AERQEYSQ EE KL RIL 239
Cdd:PRK12270 428 LW DL D REF PV G ----- GF -- G G KERMK L RD IL GV LR DS YC RTV G I EYMHI Q D P E QRR WL QE R V E - RPHEKPTR EE QK RIL 499
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 240 DR L TWS E M FE S FL AN KY TAA KRF G LEG C E A LIP GMK A LI D S AA DQ G VSS VVIGM P HRGRLNVLAN VMR KP MEAV F S EF A G 319
Cdd:PRK12270 500 SK L NAA E A FE T FL QT KY VGQ KRF S LEG G E S LIP LLD A VL D Q AA EH G LDE VVIGM A HRGRLNVLAN IVG KP YSQI F R EF E G 579
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 320 R - K P S kggdtsgd TYM GSGDVKYHLG ----- T SYDRPT I S ---------------------------------------- 353
Cdd:PRK12270 580 N l D P R -------- SAQ GSGDVKYHLG aegtf T QMFGDE I K vslaanpshleavdpvlegivrakqdrldkgeegftvlpi 651
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 354 --------- GQG I V Y E S L DM SQL PD Y TV GGTIH L VV ---- A FTT D P KK SRSS P Y C TDVAK ALAC P V FHVN A DD A EAVVRV 420
Cdd:PRK12270 652 llhgdaafa GQG V V A E T L NL SQL RG Y RT GGTIH I VV nnqv G FTT A P ES SRSS E Y A TDVAK MIQA P I FHVN G DD P EAVVRV 731
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 421 FE LA A E W RQ TW H G DVVIDL IG YRR Y GHNE I D E P MF TQP I MY QA I KRHKNALQV Y Q E K L LKD G S I SKDQIR Q IADKV Q K QL 500
Cdd:PRK12270 732 AR LA F E Y RQ RF H K DVVIDL VC YRR R GHNE G D D P SM TQP L MY DL I DAKRSVRKL Y T E A L IGR G D I TVEEAE Q ALRDY Q G QL 811
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 501 HDA F EGAK E YKP K KGDWLS S YWAGFMS P HQHS rirn T G V PV E L L REV G Y A ITR LPEGFT P H RQIAKVY E A RR H M VDS G e G 580
Cdd:PRK12270 812 ERV F NEVR E AEK K PPEPPE S VESDQGP P AGVD ---- T A V SA E V L ERI G D A HVN LPEGFT V H PKLKPLL E K RR E M ARE G - G 886
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 581 L DW GMA E A LAFG T LL A EG NHI ----------------------------------------------------------- 601
Cdd:PRK12270 887 I DW AFG E L LAFG S LL L EG TPV rlsgqdsrrgtfsqrhavlidretgeeytplqnlsddqgkflvydsllseyaamgfeyg 966
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 602 ------------------------- I F D Q F V SSGEAKW LRQT G LTV LLPHGY D GQGP E HSSAR M ERFLQ MVD E D pyqlpt 656
Cdd:PRK12270 967 ysverpdalvlweaqfgdfangaqt I I D E F I SSGEAKW GQRS G VVL LLPHGY E GQGP D HSSAR I ERFLQ LCA E G ------ 1040
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 657 ideskwfigghlgsqiqsc N WQ V VNCT TPANYFH V LRRQ LHRQF R K PL IL F A PK NL LR HPL A K S PLAE F S E S aldkdiqg 736
Cdd:PRK12270 1041 ------------------- N MT V AQPS TPANYFH L LRRQ ALSGP R R PL VV F T PK SM LR LKA A V S DVED F T E G -------- 1093
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 737 v R F KR VI M D ESST D rsfdppk QEGFK R MVF CSGK --------------------------------------------- V 771
Cdd:PRK12270 1094 - K F RP VI D D PTVD D ------- GAKVR R VLL CSGK lyydlaarrekdgrddtaivrveqlyplpraelrealarypnate V 1165
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 552837515 772 M W T QEEP M N M GA YLHVQPRF qrc M E AMGREVPM av KYSG RP SM AS T ATG FGE VHA Q EQ AD L INK A LDL 839
Cdd:PRK12270 1166 V W V QEEP A N Q GA WPFMALNL --- P E LLPDGRRL -- RRVS RP AS AS P ATG SAK VHA V EQ QE L LDE A FAR 1228
TPP_E1_OGDC_like
cd02016 Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed ...
248-461
1.29e-122
Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of 2-oxoglutarate to succinyl-CoA and carbon dioxide, a key reaction of the tricarboxylic acid cycle.
Pssm-ID: 238974 [Multi-domain]
Cd Length: 265
Bit Score: 369.94
E-value: 1.29e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 248 FE S FLA N K YTAA KRFGLEG C E A LIP GMKA LID S AA DQ GV SS VVIGM P HRGRLNVLANV MR KP M E AV FSEF agrkps K G GD 327
Cdd:cd02016 1 FE Q FLA T K FPGQ KRFGLEG A E S LIP ALDE LID R AA EL GV EE VVIGM A HRGRLNVLANV LG KP L E QI FSEF ------ E G KS 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 328 TSGDTYM GSGDVKYHLG T S Y DR P T ----------------------------------------------------- IS G 354
Cdd:cd02016 75 EFPEDDE GSGDVKYHLG Y S S DR K T psgkkvhlslapnpshleavnpvvmgktrakqdyrgdgerdkvlpilihgdaa FA G 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 355 QG I VYE S L DM S Q LP D YT V GGTIH L VV ---- A FTTDP KK SRSSPYCTDVAK ALAC P V FHVN A DD A EAVVR VFE LA A E W RQ T 430
Cdd:cd02016 155 QG V VYE T L NL S N LP G YT T GGTIH I VV nnqi G FTTDP RD SRSSPYCTDVAK MIGA P I FHVN G DD P EAVVR ATR LA L E Y RQ K 234
250 260 270
....*....|....*....|....*....|.
gi 552837515 431 WHG DVVIDL IG YRR Y GHNE I DEP M FTQP I MY 461
Cdd:cd02016 235 FKK DVVIDL VC YRR H GHNE L DEP S FTQP L MY 265
E1_dh
pfam00676 Dehydrogenase E1 component; This family uses thiamine pyrophosphate as a cofactor. This family ...
248-512
6.32e-45
Dehydrogenase E1 component; This family uses thiamine pyrophosphate as a cofactor. This family includes pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase and 2-oxoisovalerate dehydrogenase.
Pssm-ID: 395548 [Multi-domain]
Cd Length: 300
Bit Score: 163.65
E-value: 6.32e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 248 F E SFLANK Y TAAKRF G LEGCE A LIPGMKAL I DS A ADQ G vs SVV I GM p H R GRL N V LA NVM rk PM E AV F S E FA GR KPS - KGG 326
Cdd:pfam00676 9 M E DARDAL Y KRQGIR G FYHLY A GQEAAQVG I AA A LEP G -- DYI I PG - Y R DHG N L LA RGL -- SL E EI F A E LY GR VAK g KGG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 327 DTS G ------- DT Y M G S G DV kyhl G TSY --------------- DRPT I ------- SG QG IVY E S L DMSQ L PDYT V ggt I H 377
Cdd:pfam00676 84 SMH G yygakgn RF Y G G N G IL ---- G AQV plgagialaakyrgk KEVA I tlygdga AN QG DFF E G L NFAA L WKLP V --- I F 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 378 LVV ---- AFT T DPKKSRS S PYCT D V A KALAC P VF HV NAD D AE AV VRVFEL AAE WRQ T WH G DVV I D L IG YR RY GH NEI D E P 453
Cdd:pfam00676 157 VCE nnqy GIS T PAERASA S TTYA D R A RGYGI P GL HV DGM D PL AV YQASKF AAE RAR T GK G PFL I E L VT YR YG GH SMS D D P 236
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 454 MFTQ - PIM Y QAIKRH K NAL Q VYQ E K L LKD G SI S KDQIRQ I ADK V Q K QLHD AF EG A KEYKP 512
Cdd:pfam00676 237 STYR t RDE Y EEVRKK K DPI Q RFK E H L VSK G VW S EEELKA I EKE V R K EVEE AF KK A ESAPE 296
OxoGdeHyase_C
pfam16870 2-oxoglutarate dehydrogenase C-terminal; OxoGdeHyase_C is a family found immediately ...
719-837
3.17e-26
2-oxoglutarate dehydrogenase C-terminal; OxoGdeHyase_C is a family found immediately C-terminal to Transket_pyr, pfam02779. It is found at the C-terminus of 2-oxoglutarate dehydrogenase.
Pssm-ID: 465289 [Multi-domain]
Cd Length: 147
Bit Score: 104.83
E-value: 3.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 719 K S P L A EF SE saldkdiq G VR F K RVI M D ess TDRSF DP pkq E GF KR M V F CSGKV --------------------------- 771
Cdd:pfam16870 1 R S S L E EF TP -------- G TH F Q RVI P D --- PEPLV DP --- E KV KR V V L CSGKV yydllkereerggikdvaivrieqlyp 66
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 772 ------------------- M W T QEEP M N M GA YLH VQPR FQRCMEAM G REV pmav K Y S GRP SM AS T ATG FGE VH AQ EQ AD L 832
Cdd:pfam16870 67 fpfdllkeeldkypnaaei V W C QEEP K N Q GA WSF VQPR LETVLNET G HRL ---- R Y A GRP PS AS P ATG SKS VH LA EQ EA L 142
....*
gi 552837515 833 INK A L 837
Cdd:pfam16870 143 LDD A F 147
Transket_pyr
pfam02779 Transketolase, pyrimidine binding domain; This family includes transketolase enzymes, pyruvate ...
570-714
3.59e-23
Transketolase, pyrimidine binding domain; This family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases.
Pssm-ID: 460692 [Multi-domain]
Cd Length: 174
Bit Score: 97.24
E-value: 3.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 570 ARR H MVDS G EGL D W G M AE ---- AL A F G TL L AEGNHIIF ----------- D QFVSS G E A KWLRQTG - LTVLL P H G YDGQ GP 633
Cdd:pfam02779 40 GLL H PQGA G RVI D T G I AE qamv GF A N G MA L HGPLLPPV eatfsdflnra D DAIRH G A A LGKLPVP f VVTRD P I G VGED GP 119
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 634 E H S S ARMER FL QMVD edpyqlptideskwfigghlgsqiqsc NWQ VV NCTTP A NYFHV LR RQLH R QF RKP LI L FA P KN LL 713
Cdd:pfam02779 120 T H Q S VEDLA FL RAIP --------------------------- GLK VV RPSDA A ETKGL LR AAIR R DG RKP VV L RL P RQ LL 172
.
gi 552837515 714 R 714
Cdd:pfam02779 173 R 173
2-oxogl_dehyd_N
pfam16078 2-oxoglutarate dehydrogenase N-terminus; This domain is found at the N-terminus of ...
43-83
1.32e-13
2-oxoglutarate dehydrogenase N-terminus; This domain is found at the N-terminus of 2-oxoglutarate dehydrogenases.
Pssm-ID: 465008 [Multi-domain]
Cd Length: 41
Bit Score: 65.24
E-value: 1.32e-13
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 552837515 43 DSFL D G TSST Y L EEL E E R Y RAN P R SVD K SW ASF F HSM D M G V 83
Cdd:pfam16078 1 DSFL S G ANAA Y I EEL Y E Q Y LKD P S SVD P SW RAY F DNL D D G E 41
kgd
PRK12270 multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
53-108
3.26e-04
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain]
Cd Length: 1228
Bit Score: 44.50
E-value: 3.26e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 552837515 53 YL EE LEER Y R A N P R SVD K SW AS FF HSMDM G VP A ESV A E A YD A FERGEVTSPLT AA A 108
Cdd:PRK12270 10 LV EE MYQQ Y L A D P N SVD P SW RE FF ADYGP G ST A APT A A A AA A AAAASAPAAAP AA K 65
TPP_E1_PDC_ADC_BCADC
cd02000 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; ...
309-505
1.72e-03
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).
Pssm-ID: 238958 [Multi-domain]
Cd Length: 293
Bit Score: 41.33
E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 309 PMEAVFS E FA G RK -- P S KG GDT S G dt YM G SGDVKYHL G TS ------------------ YDRPTI --------- SGQ G IVY 359
Cdd:cd02000 67 DLKEMLA E LF G KE tg P C KG RGG S M -- HI G DKEKNFFG G NG ivggqvplaagaalalky RGEDRV avcffgdga TNE G DFH 144
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 360 E S L DMS --- Q LP dytvggtihl V VAFTTDPKKSR S S P Y ----- C T DV A - K A L A C -- P VFH V NAD D AE AV VRVFEL A A E W - 427
Cdd:cd02000 145 E A L NFA alw K LP ---------- V IFVCENNGYAI S T P T srqta G T SI A d R A A A Y gi P GIR V DGN D VL AV YEAAKE A V E R a 214
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552837515 428 R QT w H G DVV I DLIG YR RY GH NEI D E P M ftqpi M Y ------ QAI K R h KNALQVYQEK L LKD G SISKDQIRQ I ADK V QKQLH 501
Cdd:cd02000 215 R AG - G G PTL I EAVT YR LG GH STS D D P S ----- R Y rtkeev EEW K K - RDPILRLRKY L IEA G ILTEEELAA I EAE V KAEVE 287
....
gi 552837515 502 D A F E 505
Cdd:cd02000 288 E A V E 291
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
