|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02906 |
PLN02906 |
xanthine dehydrogenase |
23-1318 |
0e+00 |
|
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain] Cd Length: 1319 Bit Score: 1702.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 23 ETTLLAYLRrKLRLSGTKLGCGEGGCGACTVMLSKYDRFQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQ 102
Cdd:PLN02906 1 HQTLLEYLR-DLGLTGTKLGCGEGGCGACTVMVSHYDRKTGKCVHYAVNACLAPLYSVEGMHVITVEGIGNRRDGLHPVQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 103 ERIAKSHGSQCGFCTPGIVMSMYTLLRNQPE-PTIEEIENAFQGNLCRCTGYRPILQGFRTFAKD------GGCCGGSRD 175
Cdd:PLN02906 80 EALASMHGSQCGFCTPGFIMSMYALLRSSKTpPTEEQIEECLAGNLCRCTGYRPILDAFRVFAKTddalytGVSSLSLQD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 176 NPNCCLNQKKDCS--------RVILSPSLFNPEEFMPLD----PTQEPIFPPELLRLKDVPQKQLCFKGerVTWIQASTL 243
Cdd:PLN02906 160 GEPICPSTGKPCScgskttsaAGTCKSDRFQPISYSEIDgswyTEKELIFPPELLLRKLTPLKLLGNGG--LTWYRPTSL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 244 KELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISFGAACPLSIVEKTLHDAVNKLPAY 323
Cdd:PLN02906 238 QHLLELKAEYPDAKLVVGNTEVGIEMRFKNAQYPVLISPTHVPELNAIKVKDDGLEIGAAVRLSELQNLFRKVVKERPAH 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 324 KTEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSR-GIKRTVRMDHtFFPGYRKTLLAPE 402
Cdd:PLN02906 318 ETSACKAFIEQLKWFAGTQIRNVASIGGNICTASPISDLNPLWMAAGATFVIISCdGDIRSVPASD-FFLGYRKVDLKPD 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 403 EILLSIEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTAQ--VKELALCYGGMDDRTISALKTTRKQVENLWN 480
Cdd:PLN02906 397 EILLSVFLPWTRPFEYVKEFKQAHRRDDDIAIVNAGMRVKLEEKDGEwiVSDASIAYGGVAPLSVSARKTEEFLIGKPWN 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 481 EDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENCGkLDPTYASATLLFQKDPPANVQL 560
Cdd:PLN02906 477 KETLQDALKVLQKDILIKEDAPGGMVEFRKSLALSFFFKFFLWVSHQLEADGSTIET-FPESHLSAAQPFPRPSSVGMQD 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 561 FQEVPEGQSeedmVGRPLPHLAAAMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFND 640
Cdd:PLN02906 556 YETVKQGTA----VGQPEVHLSAELQVTGEAEYADDIPMPPNTLHAALVLSTKPHARILSIDDSEAKSSPGFAGIFLAKD 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 641 VPGSNKTG-IFNDETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFY-GSELKIEKG 718
Cdd:PLN02906 632 VPGDNMIGpVVHDEELFATDVVTCVGQVIGVVVADTQENAKAAARKVKVEYEELPAILSIEEAIEAGSFHpNTERRLEKG 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 719 ELTKGFS--EADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMG 796
Cdd:PLN02906 712 DVELCFAsgQCDRIIEGEVQMGGQEHFYLEPNSSLVWTSDSGNEVHMISSTQAPQKHQKYVAHVLGLPMSKVVCKTKRIG 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 797 GGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQ 876
Cdd:PLN02906 792 GGFGGKETRSAFIAAAAAVPAYLLNRPVKLTLDRDVDMMITGQRHAFLGKYKVGFTNEGKILALDLEIYNNGGNSLDLSG 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 877 SIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHF 956
Cdd:PLN02906 872 AVLERAMFHSDNVYEIPNVRIVGNVCFTNFPSNTAFRGFGGPQGMLITENWIQRIAVELNKSPEEIREMNFQGEGSVTHY 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 957 NQKLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQAGALIHVYTDGSVLLTHGG 1036
Cdd:PLN02906 952 GQVLQHCTLPQLWDELKVSCDFLKRREEVDEFNAKNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHGG 1031
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1037 TEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWED 1116
Cdd:PLN02906 1032 VEMGQGLHTKVAQVAASAFNIPLSSVFISETSTDKVPNASPTAASASSDMYGAAVLDACEQIKARMEPVASKLNFSSFAE 1111
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1117 WVIDAYENTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQV 1196
Cdd:PLN02906 1112 LVTACYFQRIDLSAHGFYITPDIGFDWKTGKGNPFNYFTYGAAFAEVEIDTLTGDFHTRRVDIVMDLGYSINPAIDIGQI 1191
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1197 EGAFVQGLGLFTLEELHYS-------PEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLAA 1269
Cdd:PLN02906 1192 EGAFVQGLGWVALEELKWGdaahkwiRPGSLFTCGPGTYKIPSVNDIPFKFNVSLLKGAPNPKAIHSSKAVGEPPFFLAA 1271
|
1290 1300 1310 1320
....*....|....*....|....*....|....*....|....*....
gi 545527502 1270 SVFFAIKDAVRAARARNSdcKTKLFRLDSPATPEKIRNACVDEFTTLCV 1318
Cdd:PLN02906 1272 SVFFAIKDAIKAARAEVG--LHGWFPLDTPATPERIRMACGDEITAPFA 1318
|
|
| mam_aldehyde_ox |
TIGR02969 |
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ... |
5-1332 |
0e+00 |
|
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain] Cd Length: 1330 Bit Score: 1535.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 5 ELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDRFQNKIVHFSANACLAPICSLHHVA 84
Cdd:TIGR02969 2 ELLFYVNGRKVVEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPSTKSIRHHPVNACLTPICSLYGAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 85 VTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFA 164
Cdd:TIGR02969 82 VTTVEGIGSTRTRLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 165 KDGGCCGgSRDNPNCCLNQKKDCSRVI-----LSPSLFNPEEFMPLDPTQEPIFPPELLRLKD-VPQKQLCFKGERVTWI 238
Cdd:TIGR02969 162 KTSGCCQ-SKENGVCCLDQGINGLPEFeegdeTSPELFSEEEFLPLDPTQELIFPPELMRMAEkQPQRTRVFYSERMMWI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 239 QASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISFGAACPLSIVEKTLHDAVN 318
Cdd:TIGR02969 241 SPVTLKELLEAKFKYPQAPVVMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHTGDGLTLGAGLSLAQVKDILADVVQ 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 319 KLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTL 398
Cdd:TIGR02969 321 KLPEETTQTYRALLKHLGTLAGSQIRNMASLGGHIISRHLDSDLNPLLAVGNCTLNLLSKEGKRQIPLSEQFLSKCPDAD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 399 LAPEEILLSIEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQVENL 478
Cdd:TIGR02969 401 LKPQEILVSVNIPYSRKWEFVSAFRQAQRQQNALAIVNSGMRVFFGEGDGIIRELSISYGGVGPTTICAKNSCQKLIGRP 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 479 WNEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENCGKLDPTYASATLLFQKDPPANV 558
Cdd:TIGR02969 481 WNEEMLDTACRLILDEVSLAGSAPGGKVEFKRTLIISFLFKFYLEVSQILKRMDPGHYPSLADKYESALEDLHSKHHWST 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 559 QLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSF 638
Cdd:TIGR02969 561 LKHQNVDSMQLPQDPIGHPIMHLSGVKHATGEAIYCDDMPAVDQELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 639 NDVPGSNKTGIfndETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEEL-PAIITIEDAIKNNSFYGSELKIEK 717
Cdd:TIGR02969 641 EHLQDANTFGT---EKLLATDKVHCVGQLVCAVIADSEVQAKQAAKHVKIVYRDLePLILTIEEAIQHKSFFEPERKLEY 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 718 GELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGG 797
Cdd:TIGR02969 718 GNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKYIQDIVAATLKLPVNKVMCHVRRVGG 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 798 GFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQS 877
Cdd:TIGR02969 798 AFGGKVGKTSIMAAITAFAANKHGRAVRCTLERGEDMLITGGRHPYLGKYKAGFMNDGRIVALDVEHYSNGGSSLDESLW 877
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 878 IMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFN 957
Cdd:TIGR02969 878 VIEMGLLKMDNAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAGLITEACITEVAAKCGLSPEKVRTINMYKEIDQTPYK 957
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 958 QKLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQAGALIHVYTDGSVLLTHGGT 1037
Cdd:TIGR02969 958 QEINAKNLFQCWRECMAKSSYSERKVAVEKFNAENYWKKRGLAVIPLKFPVGLGSVAMGQAAALVHIYLDGSVLVTHGGI 1037
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1038 EMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDW 1117
Cdd:TIGR02969 1038 EMGQGVHTKMIQVVSRELKMPMSNVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDW 1117
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1118 VIDAYENTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVE 1197
Cdd:TIGR02969 1118 AQTAFDQSISLSAVGYFRGYESNINWEKGEGHPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGHSINPALDIGQVE 1197
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1198 GAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASVFFAIKD 1277
Cdd:TIGR02969 1198 GAFIQGMGLYTIEELSYSPQGILYSRGPNQYKIPAICDIPTELHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHD 1277
|
1290 1300 1310 1320 1330
....*....|....*....|....*....|....*....|....*....|....*
gi 545527502 1278 AVRAARARNSdcKTKLFRLDSPATPEKIRNACVDEFTTLCVTGIPENCKPWSVRV 1332
Cdd:TIGR02969 1278 AVRAARQERG--LSGPWKLTSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNVPV 1330
|
|
| XdhB |
COG4631 |
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and ... |
574-1309 |
0e+00 |
|
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and metabolism];
Pssm-ID: 443669 [Multi-domain] Cd Length: 769 Bit Score: 1075.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 574 VGRPLPHLAAAMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTG-IFND 652
Cdd:COG4631 14 VGKSLPHESARLHVTGEARYIDDLPEPAGTLHAAPGLSPVAHARILSIDLSAVRAAPGVVAVLTAADIPGENDIGpIIHD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 653 ETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSELKIEKGELTKGFSEADNVVS 732
Cdd:COG4631 94 EPLLADGEVEYVGQPVFAVVAESREAARRAARLAKIEYEELPAILTIEEALAAGSFVLPPHTLRRGDADAALAAAPHRLE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 733 GEVYIGGQEHFYLETHCTIAVPkGEEGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTV 812
Cdd:COG4631 174 GEFEIGGQEHFYLEGQIALAIP-GEDGGMLVHSSTQHPSEVQHLVAHVLGVPMHAVTVEVRRMGGGFGGKESQAALFAAL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 813 VALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKI 892
Cdd:COG4631 253 AALAARKTGRPVKLRLDRDDDMVMTGKRHPFRIDYEVGFDDDGRILGLDITLAARCGWSADLSGPVADRAMFHADNAYYL 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 893 PNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMY--KEGDLTHFNQKLEGFTLSRCWE 970
Cdd:COG4631 333 PAVRITGHRCKTNTQSNTAFRGFGGPQGMLAIERVIDDIARALGLDPLDVRRRNFYgpAERNTTPYGQPVEDNILHELVD 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 971 ECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQV 1050
Cdd:COG4631 413 ELEESSDYAARRAAIAAFNAASPVLKRGLALTPVKFGISFTATHLNQAGALVHVYTDGSVQLNHGGTEMGQGLHTKVAQV 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1051 ASRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPF-------------------KKKNPS 1111
Cdd:COG4631 493 VADELGVPLERVRITATDTDKVPNTSATAASSGSDLNGMAAQDACRQIRERLAAFaaellgvepedvrfadgrvRVGGQS 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1112 GSWEDWVIDAYENTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAI 1191
Cdd:COG4631 573 LSFAELVKAAYLARVSLSATGFYKTPKIHWDRATGQGRPFYYFAYGAAVSEVEIDTLTGEYRVLRVDILHDVGRSLNPAI 652
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1192 DIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASV 1271
Cdd:COG4631 653 DIGQIEGGFVQGMGWLTTEELVWDDKGRLLTHAPSTYKIPAASDRPEDFNVALLERPNREDTIYRSKAVGEPPLMLGISV 732
|
730 740 750
....*....|....*....|....*....|....*...
gi 545527502 1272 FFAIKDAVRAARARNSDcktklFRLDSPATPEKIRNAC 1309
Cdd:COG4631 733 FEALRDAVAAVGDYRVS-----PPLDAPATPERVLMAV 765
|
|
| xanthine_xdhB |
TIGR02965 |
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the ... |
574-1309 |
0e+00 |
|
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the molybdopterin-containing large subunit (or, in, eukaryotes, the molybdopterin-binding domain) of xanthine dehydrogenase, and enzyme that reduces the purine pool by catabolizing xanthine to urate. This model is based primarily on bacterial sequences; it does not manage to include all eukaryotic xanthine dehydrogenases and thereby discriminate them from the closely related enzyme aldehyde dehydrogenase. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274367 [Multi-domain] Cd Length: 758 Bit Score: 882.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 574 VGRPLPHLAAAMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTG-IFND 652
Cdd:TIGR02965 1 VGTSLKHESAHKHVAGTAVYIDDIPEPAGTLHAALGLSTRAHARITSMDLSAVRAAPGVVDVLTAADIPGENDISpIIHD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 653 ETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAI-KNNSFYGSELKIEKGELTKGFSEADNVV 731
Cdd:TIGR02965 81 DPLLADGKVEFVGQPIFAVVATSRDAARRAARLAKIEYEELPAVLDIEEALaAGSRLVTPPLTLERGDAAAALAAAPHRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 732 SGEVYIGGQEHFYLETHCTIAVPkGEEGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVST 811
Cdd:TIGR02965 161 SGTMRIGGQEHFYLEGQIALAVP-GEDGGMHVWSSTQHPSEVQHLVAHVLGVPSHAVTVEVRRMGGGFGGKETQANLFAC 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 812 VVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYK 891
Cdd:TIGR02965 240 LAAVAARKTGRPVKLRPDRDDDMMITGKRHDFRVDYDVGFDDEGRILGVDIDMAARCGFSADLSGPVTDRALFHADNAYF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 892 IPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGD--LTHFNQKLEGFTLSRCW 969
Cdd:TIGR02965 320 LPDVTITSHPLKTNTQSNTAFRGFGGPQGMVAIERIMDEVARALGKDPLEVRKRNFYGKDErnVTPYHQTVEDNIIHEII 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 970 EECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQ 1049
Cdd:TIGR02965 400 EELEASSDYAARRAAIRAFNATSPVLKKGIALTPVKFGISFTVTHLNQAGALVHVYTDGSIHLNHGGTEMGQGLNTKVAQ 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1050 VASRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSG----------------- 1112
Cdd:TIGR02965 480 VVAEEFQVDIDRVKITATDTGKVPNTSATAASSGSDLNGMAAQDAARQIKERLVEFAAEKWQVpeedvrfapnhvrvgeq 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1113 --SWEDWVIDAYENTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPA 1190
Cdd:TIGR02965 560 rvPFAELVQQAYFARVQLSSTGFYKTPKIHWDRAKGRGRPFYYFAYGAACSEVSVDTLTGEYKVLRADILHDVGRSLNPA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1191 IDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKA-IYASKAVGEPPLFLAA 1269
Cdd:TIGR02965 640 IDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPAASDRPKDFNVRLFEWGENREDtIHRSKAVGEPPLMLGI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|
gi 545527502 1270 SVFFAIKDAVrAARARNSDCKtklfRLDSPATPEKIRNAC 1309
Cdd:TIGR02965 720 SVLFAISDAV-ASVADYRVCP----RLDAPATPERVLMAV 754
|
|
| PLN00192 |
PLN00192 |
aldehyde oxidase |
1-1309 |
0e+00 |
|
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain] Cd Length: 1344 Bit Score: 769.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1 MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDRFQNKIVHFSANACLAPICSL 80
Cdd:PLN00192 1 SSNMSLVFAVNGERFELSSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLLSKYDPVLDQVEDFTVSSCLTLLCSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 81 HHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRN-----QPEP-------TIEEIENAFQGNLC 148
Cdd:PLN00192 81 NGCSITTSEGLGNSKDGFHPIHKRFAGFHASQCGFCTPGMCISLFSALVNadktdRPEPpsgfsklTVVEAEKAVSGNLC 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 149 RCTGYRPILQGFRTFAKDggccggsRDNPNCCLNQ--KKDCSRVILSPSLfnPeefmPLDPTQEPIFPPELLrlKDVPQK 226
Cdd:PLN00192 161 RCTGYRPIVDACKSFAAD-------VDIEDLGLNSfwKKGESEEAKLSKL--P----PYNHSDHICTFPEFL--KKEIKS 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 227 QLCFKGERVTWIQASTLKELLDL----KAQHPEAKLVVGNTEIGIemkFKN-RLFPMIVCPAWIPELNAVEHGLEGISFG 301
Cdd:PLN00192 226 SLLLDSSRYRWYTPVSVEELQSLlesnNFDGVSVKLVVGNTGTGY---YKDeELYDKYIDIRHIPELSMIRRDEKGIEIG 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 302 AACPLSIVEKTLHDAVNKlpaykTEVFKGVLEQLRWFAGKQVKSVASIGGNIINAS----PiSDLNPVFMASEAKLTIVS 377
Cdd:PLN00192 303 AVVTISKAIEALREESKS-----EYVFKKIADHMEKIASRFVRNTGSIGGNLVMAQrkqfP-SDIATILLAAGSTVNIQN 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 378 RGIKRTVRMDHtFFpgyRKTLLAPEEILLSIEIPYSREGE------FFSAFKQASR-REDDIAKVTSG-MRVLFHPGTAQ 449
Cdd:PLN00192 377 ASKREKLTLEE-FL---ERPPLDSKSLLLSVEIPSWTSSSgsdtklLFETYRAAPRpLGNALPYLNAAfLAEVSQDASSG 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 450 ---VKELALCYGGM-DDRTISAlkttrKQVENLWNEDLLQNvcAGLAEELKL-----SPDAPGGMVDFRRTLTLSFFFKF 520
Cdd:PLN00192 453 givVNDCRLAFGAYgTKHAIRA-----RKVEEFLTGKVLSD--SVLYEAVRLlkgivVPEDGTSHPEYRSSLAVGFLFDF 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 521 YLTVLQ---KLERGNLENCGKLDPTYASATLLFQKDPPANVQlfQEVPEGQsEEDMVGRPLPHLAAAMQASGEAVYCDDI 597
Cdd:PLN00192 526 LSPLIEsnaKSSNGWLDGGSNTKQNPDQHDDVKKPTLLLSSK--QQVEENN-EYHPVGEPIKKVGAALQASGEAVYVDDI 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 598 PRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVP--GSN--KTGIFNDETIFAEDEVTCIGHIIGAVVT 673
Cdd:PLN00192 603 PSPKNCLYGAFIYSTKPLARVKGIKFKSNLVPQGVLAVITFKDIPkgGQNigSKTIFGPEPLFADEVTRCAGQRIALVVA 682
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 674 DTPEHAQRAAQGVKITY--EEL-PAIITIEDAIKNNSFYG--SELKIEK-GELTKGFSEADN-VVSGEVYIGGQEHFYLE 746
Cdd:PLN00192 683 DTQKHADMAANLAVVEYdtENLePPILTVEDAVKRSSLFEvpPFLYPKPvGDISKGMAEADHkILSAEIKLGSQYYFYME 762
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 747 THCTIAVPKgEEGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRC 826
Cdd:PLN00192 763 TQTALALPD-EDNCIVVYSSTQCPEYVHSVIARCLGIPEHNVRVITRRVGGGFGGKAVKSMPVATACALAAFKLQRPVRM 841
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 827 MLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSqSIMERALFHMDNCYKIPNIRGTGRLCKTNL 906
Cdd:PLN00192 842 YLNRKTDMIMAGGRHPMKITYSVGFKSDGKITALHLDILINAGISPDIS-PIMPRNIIGALKKYDWGALSFDIKVCKTNL 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 907 PSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFNQKLEG----FTLSRCWEECLASSQYHARK 982
Cdd:PLN00192 921 SSRSAMRAPGEVQGSYIAEAIIEHVASTLSMDVDSVRKINLHTYESLKLFYGDSAGepseYTLPSIWDKLASSSEFKQRT 1000
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 983 SEVDKFNEENYWKKRGLCIIPTKFGISftlsfLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRAL---KIPT 1059
Cdd:PLN00192 1001 EMVKEFNRSNKWKKRGISRVPIVHEVM-----LRPTPGKVSILSDGSIAVEVGGIEIGQGLWTKVKQMAAFGLgmiKCDG 1075
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1060 S-----KIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKK----KNPSGSWEDWVIDAYENTVSLSA 1130
Cdd:PLN00192 1076 GedlldKIRVIQSDTLSMIQGGFTAGSTTSESSCEAVRLCCVILVERLKPIKErlqeQMGSVTWDMLISQAYMQSVNLSA 1155
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1131 TGFYrTPNLgysfetnsgNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLE 1210
Cdd:PLN00192 1156 SSYY-TPDP---------SSMEYLNYGAAVSEVEVDLLTGETTILRSDIIYDCGQSLNPAVDLGQIEGAFVQGIGFFMLE 1225
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1211 ELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASVFFAIKDAVRAARAR----N 1286
Cdd:PLN00192 1226 EYTTNSDGLVVTDGTWTYKIPTVDTIPKQFNVEILNSGHHKKRVLSSKASGEPPLLLAASVHCATRAAIREARKQllswG 1305
|
1370 1380
....*....|....*....|....
gi 545527502 1287 SDCKTKL-FRLDSPATPEKIRNAC 1309
Cdd:PLN00192 1306 GIDGSDStFQLPVPATMPVVKELC 1329
|
|
| xanthine_xdhA |
TIGR02963 |
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ... |
6-524 |
8.02e-167 |
|
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274365 [Multi-domain] Cd Length: 467 Bit Score: 506.04 E-value: 8.02e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 6 LVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDRFQnKIVHFSANACLAPICSLHHVAV 85
Cdd:TIGR02963 1 IRFFLNGETVTLSDVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVGELVDGG-KLRYRSVNACIQFLPSLDGKAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 86 TTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRtFAK 165
Cdd:TIGR02963 80 VTVEDLRQPDGRLHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILDAAE-AAF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 166 DGGCCGgsrdnpncclnqkkdcsrvilspslfnpeefmPLDPTQEPIFpPELLRLKDVPQKQLCFKGERVtwIQASTLKE 245
Cdd:TIGR02963 159 DYPCSD--------------------------------PLDADRAPII-ERLRALRAGETVELNFGGERF--IAPTTLDD 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 246 LLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISFGAACPLSIVEKTLHDAVNKLPaykt 325
Cdd:TIGR02963 204 LAALKAAHPDARIVAGSTDVGLWVTKQMRDLPDVIYVGQVAELKRIEETDDGIEIGAAVTLTDAYAALAKRYPELG---- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 326 evfkgvlEQLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDhTFFPGYRKTLLAPEEIL 405
Cdd:TIGR02963 280 -------ELLRRFASLQIRNAGTLGGNIANGSPIGDSPPALIALGARLTLRKGEGRRTLPLE-DFFIDYGKTDRQPGEFV 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 406 LSIEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTaqVKELALCYGGMDDRTISALKTTRKQVENLWNEDLLQ 485
Cdd:TIGR02963 352 EALHVPRPTPGERFRAYKISKRFDDDISAVCAAFNLELDGGV--VAEIRIAFGGMAATPKRAAATEAALLGKPWNEATVE 429
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 545527502 486 NVCAGLAEELK-LSPDAPGGmvDFRRTLTLSFFFKFYLTV 524
Cdd:TIGR02963 430 AAMAALAGDFTpLSDMRASA--EYRLLTAKNLLRRFFLET 467
|
|
| CoxL |
COG1529 |
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ... |
574-1308 |
1.50e-162 |
|
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain] Cd Length: 741 Bit Score: 504.77 E-value: 1.50e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 574 VGRPLPHLAAAMQASGEAVYCDDIpRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKT--GIFN 651
Cdd:COG1529 10 IGKPVPRVDGPAKVTGRARYTDDI-RLPGMLYAAVVRSPHAHARIKSIDTSAALALPGVVAVLTGEDLPGLKFGlpGPDP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 652 DETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFY---------GSELKIEKGELTK 722
Cdd:COG1529 89 DQPPLADDKVRYVGEPVAAVVAETREAARDAAELIKVEYEPLPAVVDPEAALAPGAPLvheelpgnvAAEWRGERGDVDA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 723 GFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEeGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGK 802
Cdd:COG1529 169 AFAEADVVVEATYTTPRLAHAPMEPRAAVAEWDGD-GRLTVWASTQGPHLVRRALARALGLPPEKVRVIAPDVGGGFGGK 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 803 ETrSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERA 882
Cdd:COG1529 248 LD-VYPEEVLAALAARKLGRPVKLVLTREEDFLADTHRHATVQRVRLGADKDGKITALRHDVVADTGAYASFGEAVLPLG 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 883 LFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFNQKLEG 962
Cdd:COG1529 327 ATMATGPYAIPNVRVEARAVYTNTPPTGAYRGPGRPQAAFALESAMDELAEELGMDPVELRLRNLIRPGDFPPTGQPYDS 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 963 FTLSRCWEECLASSQYHARKSEVDKFNEEnywKKRGLciiptkfGISF----TLSFLNQAGALIHVYTDGSVLLTHGGTE 1038
Cdd:COG1529 407 GRLAECLEKAAEAFGWGERRARPAEARAG---KLRGI-------GVAAyiegSGGGGDPESARVRLNPDGSVTVYTGATD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1039 MGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRL---------------- 1102
Cdd:COG1529 477 IGQGHETVLAQIAAEELGVPPEDVRVVLGDTDLTPYGGGTGGSRSTAVGGSAVRKAAEKLREKLlelaahllgadpedle 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1103 ---EPFKKKNPSGSWEDWVIDAYEntVSLSATGFYRTPnlgysfetnsgnPFHYFSYGVACSEVEIDCLTGDHKNLRTDI 1179
Cdd:COG1529 557 fedGRVRVPGRSVSLAELAAAAYY--GGLEATGTYDPP------------TYPTYSFGAHVAEVEVDPETGEVRVLRVVA 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1180 VMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPtEFRVSLLrDCPNKKAIYASKA 1259
Cdd:COG1529 623 VHDCGRVINPLLVEGQVEGGVVQGIGQALYEELVYDEDGQLLNANFADYLVPRAADVP-EIEVIFV-ETPDPTNPLGAKG 700
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 545527502 1260 VGEPPLFLAASvffAIKDAVRAArarnsdckTKLFRLDSPATPEKIRNA 1308
Cdd:COG1529 701 VGEPGTIGVAP---AIANAVYDA--------TGVRIRDLPITPEKVLAA 738
|
|
| MoCoBD_1 |
pfam02738 |
Molybdopterin cofactor-binding domain; |
700-947 |
3.28e-119 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain] Cd Length: 244 Bit Score: 371.02 E-value: 3.28e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 700 EDAIKNNSFygselKIEKGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVAN 779
Cdd:pfam02738 3 EEPPNNVAF-----HREKGDVEAAFAEADHVVEGEYRTGRQEHFYMETRAALAVPDDEDGRLTVYSSTQGPHLVRRLVAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 780 MLGVPINRILVRVKRMGGGFGGKeTRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVA 859
Cdd:pfam02738 78 VLGIPENKVRVIVPRVGGGFGGK-TQSYPEEALAALAARKTGRPVKWVLDREEDMLATGHRHPFLIKYKVGADKDGKILA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 860 LEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPA 939
Cdd:pfam02738 157 LDVDLYADGGAYADLSPAVPERALSHLDGPYKIPNVRVDGRAVYTNTPPNGAFRGFGRPQGMFALERLMDELAEELGMDP 236
|
....*...
gi 545527502 940 EEVRRKNM 947
Cdd:pfam02738 237 LELRRRNL 244
|
|
| MoCoBD_2 |
pfam20256 |
Molybdopterin cofactor-binding domain; |
971-1237 |
1.61e-118 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain] Cd Length: 282 Bit Score: 370.71 E-value: 1.61e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 971 ECLASSQYHARKSEVDKFNEENywKKRGLCIIPTKFGISFTLSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQV 1050
Cdd:pfam20256 1 KALELSDYDERRAEQAEFNRGN--RKRGIGIAPYVEGSGLGPGALNQAGALVRLNPDGSVTVYTGGTEMGQGLETKLAQI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1051 ASRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPF---------------------KKKN 1109
Cdd:pfam20256 79 AAEALGIPPEDVRVVEGDTDTVPNGGGTGASRSTDVGGNAVLLAAEKLRERLLKIaahlleaspedlefedgkvyvKGDP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1110 PSGSWEDWVIDAYENTVSLSATGFYRTPNlgysFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNP 1189
Cdd:pfam20256 159 RSVTFAELAAAAYGEGVGLSATGFYTPPD----DETGQGPPFAYYPYGAHAAEVEVDPETGEVRVLRYVAVHDCGRVINP 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 545527502 1190 AIDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIP 1237
Cdd:pfam20256 235 AIVEGQIEGGFVQGIGLALMEELVYDEDGQLLTASLMDYKIPTAADIP 282
|
|
| XdhA |
COG4630 |
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ... |
8-494 |
2.34e-104 |
|
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];
Pssm-ID: 443668 [Multi-domain] Cd Length: 476 Bit Score: 339.81 E-value: 2.34e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 8 FFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKlgcgeggcgacTVMLSkyDRFQNKIVHFSANACLAPICSLHHVAVTT 87
Cdd:COG4630 3 FLLNGELVELSDVPPTTTLLDWLREDRGLTGTKegcaegdcgacTVVVG--ELDDGGLRYRAVNACILFLPQLDGKALVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 88 VEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRtfakdg 167
Cdd:COG4630 81 VEGLAGPDGALHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIIDAAR------ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 168 gccggsrdnpncclnqkkdcsrvilspSLFNPEEFMPLDPTQEPIfPPELLRLKDVPQKQLCFKGERvtWIQASTLKELL 247
Cdd:COG4630 155 ---------------------------AMAEAPAPDPFAADRAAV-AAALRALADGETVELGAGGSR--FLAPATLDELA 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 248 DLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISFGAACPLSIVEKTLHDAvnkLPAYkTEV 327
Cdd:COG4630 205 ALLAAHPDARLVAGATDVGLWVTKQLRDLPPVIFLGRVAELRRIEETDDGLEIGAAVTLSDAEAALAAH---FPEL-AEL 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 328 fkgvleqLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHtFFPGYRKTLLAPEEILLS 407
Cdd:COG4630 281 -------LRRFASRQIRNAGTLGGNIANGSPIGDSPPALIALGAELVLRSGDGRRTLPLED-FFLGYRKTDLQPGEFVEA 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 408 IEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTaqVKELALCYGGMDDRTISAlkttrKQVENL-----WNED 482
Cdd:COG4630 353 IRIPLPAAGQRLRAYKVSKRFDDDISAVCAAFALTLDDGT--VTEARIAFGGMAATPKRA-----RAAEAAllgqpWTEA 425
|
490
....*....|..
gi 545527502 483 LLQNVCAGLAEE 494
Cdd:COG4630 426 TVAAAAAALAQD 437
|
|
| PRK09970 |
PRK09970 |
xanthine dehydrogenase subunit XdhA; Provisional |
572-1282 |
9.94e-84 |
|
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain] Cd Length: 759 Bit Score: 291.22 E-value: 9.94e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 572 DMVGRPLPHLAAAMQASGEAVYCDDIPRyENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPG-------- 643
Cdd:PRK09970 1 MAIGKSIMRVDAIAKVTGRAKYTDDYVM-AGMLYAKYVRSPIAHGKVKSIDTEEARSLPGVEAVFTWEDVPDipfptagh 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 644 -----SNKTGIfNDETIFAeDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSF-----YGSEL 713
Cdd:PRK09970 80 pwsldPNHRDI-ADRALLT-RHVRHHGDAVAAVVARDELTAEKALKLIKVEYEELPVITDPEAALAEGAPpihngRGNLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 714 K---IEKGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVpKGEEGELELFASTQNTMKTQAFVANMLGVPINRILV 790
Cdd:PRK09970 158 KqstMSTGNVQQTIKAADYQVQGHYETPIVQHCHMENVTSYAY-MEDDGRITIVSSTQIPHIVRRVVGQALGIPWGKVRV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 791 RVKRMGGGFGGKETrstlvSTVVALAAYKT----GRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYS 866
Cdd:PRK09970 237 IKPYVGGGFGNKQD-----VLEEPLAAFLTskvgGRPVKVSLSREECFLATRTRHAFTIDIKMGVNRDGTLKGYSLDVLS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 867 NAGNTLDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKN 946
Cdd:PRK09970 312 NTGAYASHGHSIASAGGNKVAYLYPRCAYKYSSKTVYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEFRLRN 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 947 MYKEGDLTHFNQK-LEGFTLSRCWEECLASSQYHARKSEVDKfneENYWKKRGL-CIIPTKFGISFTLSfLNQAGALIHV 1024
Cdd:PRK09970 392 AAREGDANPLSGKrIYSAGLPECLEKGRKIFEWDKRRAECKN---QQGNLRRGVgVACFSYTSGTWPVG-LEIAGARLLM 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1025 YTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIY-ISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLE 1103
Cdd:PRK09970 468 NQDGTVQVQSGATEIGQGSDTVFSQMVAETVGIPVSDVRvISTQDTDVTPFDPGAYASRQSYVAGPAIRKAALELKEKIL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1104 PFKKKN---PSG-------------------SWEDWVIDAYENTvslsATGFYRTPNLGYSFETNSgnpfhyFSYGVACS 1161
Cdd:PRK09970 548 AHAAVMlhqSAMnldiidghivvkrpgeplmSLEELAMDAYYHP----ERGGQITAESSIKTTTNP------PAFGCTFV 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1162 EVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSpEGSLQTRGPS--TYKIPAFGNIPtE 1239
Cdd:PRK09970 618 DVEVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIID-EKTGVVRNPNllDYKLPTMMDLP-Q 695
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 545527502 1240 FRVSLLRDcPNKKAIYASKAVGEPPlflAASVFFAIKDAVRAA 1282
Cdd:PRK09970 696 LESAFVEI-YEPQSAYGHKSLGEPP---IISPAPAIRNAVLMA 734
|
|
| FAD_binding_5 |
pfam00941 |
FAD binding domain in molybdopterin dehydrogenase; |
234-413 |
2.26e-58 |
|
FAD binding domain in molybdopterin dehydrogenase;
Pssm-ID: 460007 [Multi-domain] Cd Length: 170 Bit Score: 198.54 E-value: 2.26e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 234 RVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISFGAACPLS-IVEKT 312
Cdd:pfam00941 2 KFGYYRPASLAEALELLAAGPDAKLVAGGTSLGPLMKLRLARPDHLIDINGIPELRGIEETDGGLEIGAAVTLSeIAEPL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 313 LHDAVNKLPayktevfkgvlEQLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHtFFP 392
Cdd:pfam00941 82 LREAYPALS-----------EALRKIASPQIRNVGTIGGNIANASPISDLPPALLALDAKVELRSGEGERTVPLED-FFL 149
|
170 180
....*....|....*....|.
gi 545527502 393 GYRKTLLAPEEILLSIEIPYS 413
Cdd:pfam00941 150 GYGKTALEPGELITAVIIPLP 170
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
552-1308 |
1.79e-56 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 213.54 E-value: 1.79e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 552 KDPPANVQLfqeVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDD-IPryENELSLRLVTSTRAHAKIKSIDTSEAEKVP 630
Cdd:PRK09800 153 NNPQATIDI---APTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDrVT--ADACVIKMLRSPHAHALITHLDVSKAEALP 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 631 GFVCFLSFNDVPGSNKTGIFN--------DETIFAEdEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDA 702
Cdd:PRK09800 228 GVVHVITHLNCPDIYYTPGGQsapepsplDRRMFGK-KMRHVGDRVAAVVAESEEIALEALKLIDVEYEVLKPVMSIDEA 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 703 IKNNS--------FY-------------GSELKIEK-----------------------GELTKGFSEADNVVSGEVYIG 738
Cdd:PRK09800 307 MAEDApvvhdepvVYvagapdtleddnsHAAQRGEHmiinfpigsrprkniaasihghiGDMDKGFADADVIIERTYNST 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 739 GQEHFYLETHCTIAVPKGEEgeLELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKEtrSTLVSTVVALAAY 818
Cdd:PRK09800 387 QAQQCPTETHICFTRMDGDR--LVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQ--DILLEEVCAWATC 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 819 KTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRGT 898
Cdd:PRK09800 463 VTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQ 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 899 GRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGD----LTHFNQKLEGFTLSRCWEECLA 974
Cdd:PRK09800 543 VTTYYSNICPNGAYQGYGAPKGNFAITMALAELAEQLQIDQLEIIERNRVHEGQelkiLGAIGEGKAPTSVPSAASCALE 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 975 SSQYHARKS---EVDKFNEENYWKKRGLCIIPTKFGIsftlSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVA 1051
Cdd:PRK09800 623 EILRQGREMiqwSSPKPQNGDWHIGRGVAIIMQKSGI----PDIDQANCMIKLESDGTFIVHSGGADIGTGLDTVVTKLA 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1052 SRALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRL---------EP-----------FKKKNPS 1111
Cdd:PRK09800 699 AEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARLAAENLREKIlfhgaqmlgEPvadvqlatpgvVRGKKGE 778
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1112 GSWEDWVIDAYENT--VSLSATGFYRTPNLGysfetnsgnpfhyFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNP 1189
Cdd:PRK09800 779 VSFGDIAHKGETGTgfGSLVGTGSYITPDFA-------------FPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNP 845
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 1190 AIDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLrdcPNKKAI--YASKAVGEPPLFL 1267
Cdd:PRK09800 846 ELALGQIYGATLRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLV---PSDDKVgpFGAKSISEIGVNG 922
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 545527502 1268 AA-SVFFAIKDAVraararnsdcktKLFRLDSPATPEKIRNA 1308
Cdd:PRK09800 923 AApAIATAIHDAC------------GIWLREWHFTPEKILTA 952
|
|
| Ald_Xan_dh_C |
pfam01315 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; |
588-694 |
9.71e-43 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain] Cd Length: 107 Bit Score: 151.23 E-value: 9.71e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 588 SGEAVYCDDIPRYENELsLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKT-GIFNDETIFAEDEVTCIGH 666
Cdd:pfam01315 1 TGEAVYVDDIPAPGNLY-GAFVRSTIAHAKIVSIDTSAALALPGVVAVITAKDLPGGNYNiGPIPLDPLFATDKVRHVGQ 79
|
90 100
....*....|....*....|....*...
gi 545527502 667 IIGAVVTDTPEHAQRAAQGVKITYEELP 694
Cdd:pfam01315 80 PIAAVVADDEETARRAAKLVKVEYEELP 107
|
|
| Ald_Xan_dh_C |
smart01008 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ... |
588-694 |
3.28e-40 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain] Cd Length: 107 Bit Score: 144.20 E-value: 3.28e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 588 SGEAVYCDDIpRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFN-DETIFAEDEVTCIGH 666
Cdd:smart01008 1 TGEARYGDDI-RLPGMLHAAVVRSPVAHARIKSIDTSAARAMPGVVAVLTAKDVPGLNDFGPLGpDEPVLADDKVRYVGQ 79
|
90 100
....*....|....*....|....*...
gi 545527502 667 IIGAVVTDTPEHAQRAAQGVKITYEELP 694
Cdd:smart01008 80 PVAAVVAETEEAARDAAEAVKVEYEELP 107
|
|
| CutS |
COG2080 |
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ... |
8-165 |
1.16e-37 |
|
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441683 [Multi-domain] Cd Length: 155 Bit Score: 138.69 E-value: 1.16e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 8 FFVNGKKVvEKNADPETTLLAYLRRKLRLSGTKlgcgeggcgactvmlskydrfqnK----------IVHF---SANACL 74
Cdd:COG2080 6 LTVNGKPV-EVDVDPDTPLLDVLRDDLGLTGTK-----------------------FgcghgqcgacTVLVdgkAVRSCL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 75 APICSLHHVAVTTVEGIGSTKsRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYR 154
Cdd:COG2080 62 TLAVQADGKEITTIEGLAEDG-ELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYV 140
|
170
....*....|.
gi 545527502 155 PILQGFRTFAK 165
Cdd:COG2080 141 RIVRAVKRAAA 151
|
|
| CutB |
COG1319 |
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion] ... |
236-512 |
1.79e-34 |
|
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 440930 [Multi-domain] Cd Length: 285 Bit Score: 134.09 E-value: 1.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 236 TWIQASTLKELLDLKAQH-PEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISFGAACPLSIVEKtlH 314
Cdd:COG1319 5 EYHRPTSLEEALALLAEHgPDARVLAGGTDLLPLMKLRLARPEHLVDINRIPELRGIEEEGGGLRIGALVTHAELAA--S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 315 DAVNklpayktEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHtFFPGY 394
Cdd:COG1319 83 PLVR-------ERYPLLAEAARAIASPQIRNRGTIGGNLANADPAADLPPALLALDATVELAGPDGERTIPAAD-FFLGP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 395 RKTLLAPEEILLSIEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTaqVKELALCYGGMDDRTISALKTTRKQ 474
Cdd:COG1319 155 GETALEPGELITAVRLPAPPAGAGSAYLKVGRRASDAIALVSVAVALRLDGGT--IRDARIALGGVAPTPWRAREAEAAL 232
|
250 260 270
....*....|....*....|....*....|....*...
gi 545527502 475 VENLWNEDLLQNVCAGLAEELKLSPDAPGGmVDFRRTL 512
Cdd:COG1319 233 AGKPLSEEAIEAAAEAAAAAADPIDDVRAS-AEYRRHL 269
|
|
| Fer2_2 |
pfam01799 |
[2Fe-2S] binding domain; |
87-158 |
1.01e-33 |
|
[2Fe-2S] binding domain;
Pssm-ID: 460336 [Multi-domain] Cd Length: 73 Bit Score: 124.08 E-value: 1.01e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545527502 87 TVEGIGSTKSrlHPVQERIAKSHGSQCGFCTPGIVMSMYTLL-RNQPEPTIEEIENAFQGNLCRCTGYRPILQ 158
Cdd:pfam01799 1 TIEGLAESGG--EPVQQAFAEAGAVQCGYCTPGMIMSAYALLeRNPPPPTEAEIREALSGNLCRCTGYRRIVD 71
|
|
| glyceraldDH_gamma |
NF041020 |
glyceraldehyde dehydrogenase subunit gamma; |
10-165 |
5.54e-28 |
|
glyceraldehyde dehydrogenase subunit gamma;
Pssm-ID: 468949 [Multi-domain] Cd Length: 162 Bit Score: 111.43 E-value: 5.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 10 VNGKKVvEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYdrfqnkivhfSANACLAPICSLHHVAVTTVE 89
Cdd:NF041020 15 VNGVWY-EAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGK----------SVKSCTVLAVQADGAEITTIE 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545527502 90 GIGStKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAK 165
Cdd:NF041020 84 GLSK-DGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQ 158
|
|
| CO_deh_flav_C |
pfam03450 |
CO dehydrogenase flavoprotein C-terminal domain; |
420-524 |
5.91e-25 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 460921 [Multi-domain] Cd Length: 102 Bit Score: 100.33 E-value: 5.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 420 SAFKQASRREDDIAKVTSGMRVLFHPGTaqVKELALCYGGMDDRTISALKTTRKQVENLWNEDLLQNVCAGLAEELKLsP 499
Cdd:pfam03450 1 AAYKQAKRRDDDIAIVNAAFRVRLDGGT--VEDARIAFGGVAPTPIRATEAEAALIGKPWDEETLEAAAALLLEDLSP-L 77
|
90 100
....*....|....*....|....*
gi 545527502 500 DAPGGMVDFRRTLTLSFFFKFYLTV 524
Cdd:pfam03450 78 SDPRGSAEYRRHLARSLLFRFLLEA 102
|
|
| pucE |
TIGR03198 |
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ... |
5-165 |
3.85e-23 |
|
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.
Pssm-ID: 132242 [Multi-domain] Cd Length: 151 Bit Score: 96.84 E-value: 3.85e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 5 ELVFFVNGKKVvEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSkydrfqNKIvhfsANACLAPICSLHHVA 84
Cdd:TIGR03198 3 QFRFTVNGQAW-EVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLID------GKL----ANACLTMAYQADGHE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 85 VTTVEGIgsTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFA 164
Cdd:TIGR03198 72 ITTIEGI--AENELDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSACRIR 149
|
.
gi 545527502 165 K 165
Cdd:TIGR03198 150 R 150
|
|
| 4hydroxCoAred |
TIGR03193 |
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ... |
10-164 |
6.71e-23 |
|
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.
Pssm-ID: 132237 [Multi-domain] Cd Length: 148 Bit Score: 96.10 E-value: 6.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 10 VNGKKVVEKNADpETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDRFqnkivhfsanAC--LAPICSLHHVAvtT 87
Cdd:TIGR03193 6 VNGRWREDAVAD-NMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRL----------ACstLAHRVAGRKVE--T 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545527502 88 VEGIgSTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFA 164
Cdd:TIGR03193 73 VEGL-ATNGRLSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEAAA 148
|
|
| Se_dep_XDH |
TIGR03311 |
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ... |
8-165 |
8.71e-21 |
|
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 132354 [Multi-domain] Cd Length: 848 Bit Score: 99.15 E-value: 8.71e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 8 FFVNGKKVVeknADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYdrfqnkivhfSANACLAPICSLHHVAVTT 87
Cdd:TIGR03311 3 FIVNGREVD---VNEEKKLLEFLREDLRLTGVKNGCGEGACGACTVIVNGK----------AVRACRFTTAKLAGKEITT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 88 VEGigstksrLHPVQERI-----AKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRT 162
Cdd:TIGR03311 70 VEG-------LTEREKDVyawafAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAVRL 142
|
...
gi 545527502 163 FAK 165
Cdd:TIGR03311 143 AAK 145
|
|
| PRK09971 |
PRK09971 |
xanthine dehydrogenase subunit XdhB; Provisional |
239-458 |
3.45e-20 |
|
xanthine dehydrogenase subunit XdhB; Provisional
Pssm-ID: 182175 [Multi-domain] Cd Length: 291 Bit Score: 92.41 E-value: 3.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 239 QASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEG-ISFGAACPLSIVEKtlHDAV 317
Cdd:PRK09971 9 EAATLEEAIELLADNPQAKLIAGGTDVLIQLHHHNDRYRHLVSIHNIAELRGITLAEDGsIRIGAATTFTQIIE--DPII 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 318 NK-LPAyktevfkgVLEQLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMdHTFFPGYRK 396
Cdd:PRK09971 87 QKhLPA--------LAEAAVSIGGPQIRNVATIGGNICNGATSADSAPPLFALDAKLEIHSPNGVRFVPI-NGFYTGPGK 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545527502 397 TLLAPEEILLSIEI-PYSREGEFFSAFKQASRREDDIAkvTSGMRVLFHPGTAQVKELALCYG 458
Cdd:PRK09971 158 VSLEHDEILVAFIIpPEPYEHAGGAYIKYAMRDAMDIA--TIGCAVLCRLDNGNFEDLRLAFG 218
|
|
| CO_deh_flav_C |
smart01092 |
CO dehydrogenase flavoprotein C-terminal domain; |
421-524 |
6.55e-20 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 215021 [Multi-domain] Cd Length: 102 Bit Score: 86.13 E-value: 6.55e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 421 AFKQASRREDDIAKVTSGMRVLFHPGTaqVKELALCYGGMDDRTISALKTTRKQVENLWNEDLLQNVCAGLAEELKLSPD 500
Cdd:smart01092 1 AYKKSRRRDGDIALVSAAVALTLDGGR--VTEARIALGGVAPTPKRAAEAEAALVGKPLTDEALARAAAAALAQDFTPLS 78
|
90 100
....*....|....*....|....
gi 545527502 501 APGGMVDFRRTLTLSFFFKFYLTV 524
Cdd:smart01092 79 DMRASAEYRRQLAANLLRRALLEA 102
|
|
| PRK11433 |
PRK11433 |
aldehyde oxidoreductase 2Fe-2S subunit; Provisional |
5-158 |
2.09e-17 |
|
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
Pssm-ID: 236910 [Multi-domain] Cd Length: 217 Bit Score: 82.51 E-value: 2.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 5 ELVFFVNGKkVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYdrfqnkivhfSANACLApICSLHH-V 83
Cdd:PRK11433 51 PVTLKVNGK-TEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGR----------RLNACLT-LAVMHQgA 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 84 AVTTVEGIGsTKSRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRN---------------QPEPTIEEIENAFQGNLC 148
Cdd:PRK11433 119 EITTIEGLG-SPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKEikdgipshvtvdltaAPELTADEIRERMSGNIC 197
|
170
....*....|
gi 545527502 149 RCTGYRPILQ 158
Cdd:PRK11433 198 RCGAYSNILE 207
|
|
| PRK09908 |
PRK09908 |
xanthine dehydrogenase iron sulfur-binding subunit XdhC; |
85-158 |
5.97e-16 |
|
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
Pssm-ID: 182139 [Multi-domain] Cd Length: 159 Bit Score: 76.49 E-value: 5.97e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545527502 85 VTTVEGIGSTKSrLHPVQERIAKSHGSQCGFCTPGIVMSMYTLL---RNQPePTIEEIENAFQGNLCRCTGYRPILQ 158
Cdd:PRK09908 76 IRTLEGEAKGGK-LSHVQQAYAKSGAVQCGFCTPGLIMATTAMLakpREKP-LTITEIRRGLAGNLCRCTGYQMIVN 150
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
70-158 |
1.76e-03 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 42.90 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545527502 70 ANACLAPICSLHHVAVTTVEGIGSTKsRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTIEEIENAFQGNLCR 149
Cdd:PRK09800 56 VNASLLIAAQLEKADIRTAESLGKWN-ELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSR 134
|
....*....
gi 545527502 150 CTGYRPILQ 158
Cdd:PRK09800 135 DAGWQQYYQ 143
|
|
| |
