|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00191 |
PLN00191 |
enolase |
2-432 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 849.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 2 AVERIHAREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKsRFLGKGVLQAVDHINSTVAPALVGsg 81
Cdd:PLN00191 27 TITKVKARQIIDSRGNPTVEVDLHTSKGMFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALIG-- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 82 LSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHIADLAGNSDLILPVPAFNVINGGSHAGN 161
Cdd:PLN00191 104 MDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKLVLPVPAFNVINGGSHAGN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 162 KLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYTDKIV 241
Cdd:PLN00191 184 KLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKYGQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYTGKIK 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 242 IGMDVAASEFY-RDGKYDLDFKSPD-DPSRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDD 319
Cdd:PLN00191 264 IGMDVAASEFYtKDKKYDLDFKEENnDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSLEDVQIVGDD 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 320 LTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPC 399
Cdd:PLN00191 344 LLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIKTGAPC 423
|
410 420 430
....*....|....*....|....*....|...
gi 543259198 400 RSERLAKYNQLMRIEEELGDEARFAGHNFRNPS 432
Cdd:PLN00191 424 RSERLAKYNQLLRIEEELGDEAVYAGENFRKPV 456
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
5-416 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 792.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 5 RIHAREILDSRGNPTVEVDLYT-HKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGsgLS 83
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTeDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIG--MD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 84 VVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHIADLAgnsDLILPVPAFNVINGGSHAGNKL 163
Cdd:cd03313 79 VTDQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLA---AYVLPVPMFNVINGGAHAGNKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 164 AMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYTD--KIV 241
Cdd:cd03313 156 DFQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGGLLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPgkKIA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 242 IGMDVAASEFYRDGKYDLDfkspDDPSRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQIVGDD 319
Cdd:cd03313 236 IALDVAASEFYDEGKYVYD----SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGdkIQIVGDD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 320 LTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPC 399
Cdd:cd03313 312 LFVTNPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPC 391
|
410
....*....|....*..
gi 543259198 400 RSERLAKYNQLMRIEEE 416
Cdd:cd03313 392 RSERTAKYNQLLRIEEE 408
|
|
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
2-430 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 744.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 2 AVERIHAREILDSRGNPTVEVDLYTHKGMF-RAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGs 80
Cdd:COG0148 3 RIEDVHAREILDSRGNPTVEVEVTLEDGAVgRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 81 gLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHiadLAGNSDLILPVPAFNVINGGSHAG 160
Cdd:COG0148 82 -MDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRY---LGGVNAKTLPVPMMNIINGGAHAD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 161 NKLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKygKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYT--D 238
Cdd:COG0148 158 NNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEK--GLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKpgE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 239 KIVIGMDVAASEFYRDGKYDLDFKSpddpsRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQIV 316
Cdd:COG0148 236 DIALALDVAASEFYKDGKYHLKGEG-----KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGdkVQLV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 317 GDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTG 396
Cdd:COG0148 311 GDDLFVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTG 390
|
410 420 430
....*....|....*....|....*....|....*
gi 543259198 397 APCRSERLAKYNQLMRIEEELGDEARFAGHN-FRN 430
Cdd:COG0148 391 SPSRSERVAKYNQLLRIEEELGDAARYAGRSaFKR 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
3-431 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 622.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 3 VERIHAREILDSRGNPTVEVDLYTHKGMF-RAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGsg 81
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFgRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIG-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 82 LSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHiadLAGNSDLILPVPAFNVINGGSHAGN 161
Cdd:TIGR01060 79 MDATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRY---LGGFNAYVLPVPMMNIINGGAHADN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 162 KLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYgkDATNVGDEGGFAPNILENSEALELLKEAIDKAGYT--DK 239
Cdd:TIGR01060 156 NLDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKG--LATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKpgED 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 240 IVIGMDVAASEFY--RDGKYDLDFKSpddpsRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQI 315
Cdd:TIGR01060 234 VALALDCAASEFYdeEDGKYVYKGEN-----KQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGdkVQI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 316 VGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 395
Cdd:TIGR01060 309 VGDDLFVTNTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKT 388
|
410 420 430
....*....|....*....|....*....|....*.
gi 543259198 396 GAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNP 431
Cdd:TIGR01060 389 GSLSRSERIAKYNQLLRIEEELGDSARYAGKNSFYR 424
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
143-432 |
0e+00 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 520.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 143 LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSE 222
Cdd:pfam00113 2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQSATNVGDEGGFAPNLQSNKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 223 ALELLKEAIDKAGYTDKIVIGMDVAASEFY--RDGKYDLDFKSPD-DPSRYISGDELGDLYQSFVRDYPVVSIEDPFDQD 299
Cdd:pfam00113 82 ALDLIVEAIEKAGYKGKIKIAMDVASSEFYnkKDGKYDLDFKGEKsDKSKKLTSAQLADLYEELVKKYPIVSIEDPFDED 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 300 DWEAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETE 377
Cdd:pfam00113 162 DWEAWKYLTERLGdkVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 543259198 378 DTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPS 432
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00191 |
PLN00191 |
enolase |
2-432 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 849.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 2 AVERIHAREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKsRFLGKGVLQAVDHINSTVAPALVGsg 81
Cdd:PLN00191 27 TITKVKARQIIDSRGNPTVEVDLHTSKGMFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALIG-- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 82 LSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHIADLAGNSDLILPVPAFNVINGGSHAGN 161
Cdd:PLN00191 104 MDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKLVLPVPAFNVINGGSHAGN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 162 KLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYTDKIV 241
Cdd:PLN00191 184 KLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKYGQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYTGKIK 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 242 IGMDVAASEFY-RDGKYDLDFKSPD-DPSRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDD 319
Cdd:PLN00191 264 IGMDVAASEFYtKDKKYDLDFKEENnDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSLEDVQIVGDD 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 320 LTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPC 399
Cdd:PLN00191 344 LLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIKTGAPC 423
|
410 420 430
....*....|....*....|....*....|...
gi 543259198 400 RSERLAKYNQLMRIEEELGDEARFAGHNFRNPS 432
Cdd:PLN00191 424 RSERLAKYNQLLRIEEELGDEAVYAGENFRKPV 456
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-427 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 811.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 1 MAVERIHAREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGs 80
Cdd:PTZ00081 2 STIKSIKAREILDSRGNPTVEVDLTTEKGVFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALIG- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 81 gLSVVDQEKIDNLMLE-MDGTEN-----KSKFGANAILGVSLAVCKAGAAEKDVPLYRHIADLAGN--SDLILPVPAFNV 152
Cdd:PTZ00081 81 -KDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKptDKFVLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 153 INGGSHAGNKLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAID 232
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKYGLDATNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 233 KAGYTDKIVIGMDVAASEFYRDGK--YDLDFKSPDDP-SRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTA 309
Cdd:PTZ00081 240 KAGYEGKVKICMDVAASEFYDKEKkvYDLDFKNPNNDkSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKLTA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 310 NVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVG 387
Cdd:PTZ00081 320 AIGqkVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLVVG 399
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 543259198 388 LCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHN 427
Cdd:PTZ00081 400 LGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAGEN 439
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
5-416 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 792.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 5 RIHAREILDSRGNPTVEVDLYT-HKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGsgLS 83
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTeDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIG--MD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 84 VVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHIADLAgnsDLILPVPAFNVINGGSHAGNKL 163
Cdd:cd03313 79 VTDQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLA---AYVLPVPMFNVINGGAHAGNKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 164 AMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYTD--KIV 241
Cdd:cd03313 156 DFQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGGLLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPgkKIA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 242 IGMDVAASEFYRDGKYDLDfkspDDPSRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQIVGDD 319
Cdd:cd03313 236 IALDVAASEFYDEGKYVYD----SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGdkIQIVGDD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 320 LTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPC 399
Cdd:cd03313 312 LFVTNPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPC 391
|
410
....*....|....*..
gi 543259198 400 RSERLAKYNQLMRIEEE 416
Cdd:cd03313 392 RSERTAKYNQLLRIEEE 408
|
|
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
2-430 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 744.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 2 AVERIHAREILDSRGNPTVEVDLYTHKGMF-RAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGs 80
Cdd:COG0148 3 RIEDVHAREILDSRGNPTVEVEVTLEDGAVgRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 81 gLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHiadLAGNSDLILPVPAFNVINGGSHAG 160
Cdd:COG0148 82 -MDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRY---LGGVNAKTLPVPMMNIINGGAHAD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 161 NKLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKygKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYT--D 238
Cdd:COG0148 158 NNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEK--GLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKpgE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 239 KIVIGMDVAASEFYRDGKYDLDFKSpddpsRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQIV 316
Cdd:COG0148 236 DIALALDVAASEFYKDGKYHLKGEG-----KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGdkVQLV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 317 GDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTG 396
Cdd:COG0148 311 GDDLFVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTG 390
|
410 420 430
....*....|....*....|....*....|....*
gi 543259198 397 APCRSERLAKYNQLMRIEEELGDEARFAGHN-FRN 430
Cdd:COG0148 391 SPSRSERVAKYNQLLRIEEELGDAARYAGRSaFKR 425
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-430 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 719.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 1 MAVERIHAREILDSRGNPTVEVDLYTHKGMF-RAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVG 79
Cdd:PRK00077 2 SKIEDIIAREILDSRGNPTVEVEVTLEDGAFgRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 80 sgLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHiadLAGNSDLILPVPAFNVINGGSHA 159
Cdd:PRK00077 82 --LDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRY---LGGPNAKVLPVPMMNIINGGAHA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 160 GNKLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKyGKdATNVGDEGGFAPNILENSEALELLKEAIDKAGYT-- 237
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEK-GL-STAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKpg 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 238 DKIVIGMDVAASEFYRDGKYDLDFKSpddpsryISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQI 315
Cdd:PRK00077 235 EDIALALDCAASEFYKDGKYVLEGEG-------LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGdkVQL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 316 VGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 395
Cdd:PRK00077 308 VGDDLFVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKT 387
|
410 420 430
....*....|....*....|....*....|....*.
gi 543259198 396 GAPCRSERLAKYNQLMRIEEELGDEARFAGHN-FRN 430
Cdd:PRK00077 388 GSLSRSERIAKYNQLLRIEEELGDAARYAGKKaFKN 423
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
3-431 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 622.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 3 VERIHAREILDSRGNPTVEVDLYTHKGMF-RAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGsg 81
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFgRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIG-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 82 LSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHiadLAGNSDLILPVPAFNVINGGSHAGN 161
Cdd:TIGR01060 79 MDATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRY---LGGFNAYVLPVPMMNIINGGAHADN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 162 KLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYgkDATNVGDEGGFAPNILENSEALELLKEAIDKAGYT--DK 239
Cdd:TIGR01060 156 NLDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKG--LATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKpgED 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 240 IVIGMDVAASEFY--RDGKYDLDFKSpddpsRYISGDELGDLYQSFVRDYPVVSIEDPFDQDDWEAWSKFTANVG--IQI 315
Cdd:TIGR01060 234 VALALDCAASEFYdeEDGKYVYKGEN-----KQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGdkVQI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 316 VGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 395
Cdd:TIGR01060 309 VGDDLFVTNTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKT 388
|
410 420 430
....*....|....*....|....*....|....*.
gi 543259198 396 GAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNP 431
Cdd:TIGR01060 389 GSLSRSERIAKYNQLLRIEEELGDSARYAGKNSFYR 424
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
143-432 |
0e+00 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 520.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 143 LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRIGAEVYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSE 222
Cdd:pfam00113 2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQSATNVGDEGGFAPNLQSNKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 223 ALELLKEAIDKAGYTDKIVIGMDVAASEFY--RDGKYDLDFKSPD-DPSRYISGDELGDLYQSFVRDYPVVSIEDPFDQD 299
Cdd:pfam00113 82 ALDLIVEAIEKAGYKGKIKIAMDVASSEFYnkKDGKYDLDFKGEKsDKSKKLTSAQLADLYEELVKKYPIVSIEDPFDED 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 300 DWEAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETE 377
Cdd:pfam00113 162 DWEAWKYLTERLGdkVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 543259198 378 DTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPS 432
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
3-134 |
8.20e-84 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 252.68 E-value: 8.20e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 3 VERIHAREILDSRGNPTVEVDLYTHKG-MFRAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVDHINSTVAPALVGsg 81
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGtFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIG-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 543259198 82 LSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHI 134
Cdd:pfam03952 79 MDATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
266-388 |
2.18e-21 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 92.39 E-value: 2.18e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 266 DPSRYISGDELGDLYQSfVRDYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDDLTVTNPKRIErAVEEKACNCLLLKVN 345
Cdd:cd00308 100 DANGAWTPKEAIRLIRA-LEKYGLAWIEEPCAPDDLEGYAALRRRTGIPIAADESVTTVDDALE-ALELGAVDILQIKPT 177
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 543259198 346 QIGSVTEAIQACKLAQENGWGVMVSHRSG-ETEDTFIADLVVGL 388
Cdd:cd00308 178 RVGGLTESRRAADLAEAFGIRVMVHGTLEsSIGTAAALHLAAAL 221
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
3-422 |
5.61e-16 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 78.69 E-value: 5.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 3 VERIHAREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRdndksrflgkgvlqAVDHINSTVAPALVGsgL 82
Cdd:PRK08350 4 IENIIGRVAVLRGGKYSVEVDVITDSGFGRFAAPIDENPSLYIAEAHR--------------AVSEVDEIIGPELIG--F 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 83 SVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKDVPLYRHIadlAGNSDLILPVPAFNVINGgshagnk 162
Cdd:PRK08350 68 DASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYI---GGTFTTELPVPILEFAED------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 163 lAMQEFMILpvgaesFRDAMRIGAEVyhnlksvikekygkDATNvgdeggfapNILENSE--ALELLKEAIDKAGytdkI 240
Cdd:PRK08350 138 -ENFEYYVL------VRDLMEITDVV--------------DAVN---------KILENSKevSLEGLSKASEKAG----D 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 241 VIGMDVAASefyrdgkydLDFKSPDDPSRYIsgdelgdlyqSFVRDYPVVSIEDPFDQddwEAWSKFTANV-GIQIVGDD 319
Cdd:PRK08350 184 ELGLEVALG---------IAQKREMETEKVL----------NLVEDNNIAYIKPIGDE---ELFLELIAGThGVFIDGEY 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 320 LTvtnpkRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGL-CTGQIktgap 398
Cdd:PRK08350 242 LF-----RTRNILDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLrCPAML----- 311
|
410 420
....*....|....*....|....
gi 543259198 399 CRSERLAKYNQLMRIEEELGDEAR 422
Cdd:PRK08350 312 IHKDSVEKINELNRIAEDLGERGR 335
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
286-369 |
5.95e-09 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 57.52 E-value: 5.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 286 DYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDDlTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGW 365
Cdd:COG4948 207 DLGLEWIEQPLPAEDLEGLAELRRATPVPIAADE-SLTSRADFRRLIEAGAVDIVNIKLSKVGGLTEALRIAALAEAHGV 285
|
....
gi 543259198 366 GVMV 369
Cdd:COG4948 286 PVMP 289
|
|
| MLE_like |
cd03315 |
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this ... |
284-370 |
4.54e-05 |
|
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and residues that can function as general acid/base catalysts, a Lys-X-Lys motif and another conserved lysine. Despite these conserved residues, the members of the MLE subgroup, like muconate lactonizing enzyme, o-succinylbenzoate synthase (OSBS) and N-acylamino acid racemase (NAAAR), catalyze different reactions.
Pssm-ID: 239431 [Multi-domain] Cd Length: 265 Bit Score: 45.02 E-value: 4.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 284 VRDYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDDlTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQEN 363
Cdd:cd03315 152 LEDLGLDYVEQPLPADDLEGRAALARATDTPIMADE-SAFTPHDAFRELALGAADAVNIKTAKTGGLTKAQRVLAVAEAL 230
|
....*..
gi 543259198 364 GWGVMVS 370
Cdd:cd03315 231 GLPVMVG 237
|
|
| L-Ala-DL-Glu_epimerase |
cd03319 |
L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The ... |
284-369 |
7.04e-05 |
|
L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239435 [Multi-domain] Cd Length: 316 Bit Score: 44.49 E-value: 7.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 284 VRDYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDDlTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQEN 363
Cdd:cd03319 200 LAELGVELIEQPVPAGDDDGLAYLRDKSPLPIMADE-SCFSAADAARLAGGGAYDGINIKLMKTGGLTEALRIADLARAA 278
|
....*.
gi 543259198 364 GWGVMV 369
Cdd:cd03319 279 GLKVMV 284
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
286-367 |
3.73e-03 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 39.14 E-value: 3.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 286 DYPVVSIEDPFDQDDWEAWSKFTANVGIQIVGDDlTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGW 365
Cdd:cd03317 202 EYGLLMIEQPLAADDLIDHAELQKLLKTPICLDE-SIQSAEDARKAIELGACKIINIKPGRVGGLTEALKIHDLCQEHGI 280
|
..
gi 543259198 366 GV 367
Cdd:cd03317 281 PV 282
|
|
| MAL |
cd03314 |
Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the ... |
265-391 |
4.48e-03 |
|
Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the main catabolic pathway for glutamate. MAL belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239430 [Multi-domain] Cd Length: 369 Bit Score: 38.92 E-value: 4.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543259198 265 DDPSRYIsgDELGDLYQSfVRDYPVVsIEDPFD----QDDWEAWSKFTA-----NVGIQIVGDDLTVTnPKRIERAVEEK 335
Cdd:cd03314 209 PDPDRAA--DYLATLEEA-AAPFPLR-IEGPMDagsrEAQIERMAALRAeldrrGVGVRIVADEWCNT-LEDIRDFADAG 283
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 543259198 336 ACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTG 391
Cdd:cd03314 284 AAHMVQIKTPDLGGIDNTIDAVLYCKEHGVGAYLGGSCNETDISARVTVHVALATR 339
|
|
| |
