endothelial differentiation-related factor 1 [Microtus ochrogaster]
EDF1/MBF1 family transcription factor( domain architecture ID 12094462)
EDF1/MBF1 family transcription factor such as vertebrate endothelial differentiation-related factor (EDF1) and multiprotein bridging factor 1 (MBF1), which function as transcriptional coactivators
List of domain hits
Name | Accession | Description | Interval | E-value | ||
MBF1 | pfam08523 | Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 ... |
5-71 | 3.86e-26 | ||
Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif (pfam01381) is found to its C-terminus. : Pssm-ID: 462508 Cd Length: 68 Bit Score: 93.46 E-value: 3.86e-26
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aMBF1 | COG1813 | Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ... |
76-132 | 7.77e-14 | ||
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis]; : Pssm-ID: 441418 [Multi-domain] Cd Length: 70 Bit Score: 62.26 E-value: 7.77e-14
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Name | Accession | Description | Interval | E-value | ||
MBF1 | pfam08523 | Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 ... |
5-71 | 3.86e-26 | ||
Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif (pfam01381) is found to its C-terminus. Pssm-ID: 462508 Cd Length: 68 Bit Score: 93.46 E-value: 3.86e-26
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aMBF1 | COG1813 | Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ... |
76-132 | 7.77e-14 | ||
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis]; Pssm-ID: 441418 [Multi-domain] Cd Length: 70 Bit Score: 62.26 E-value: 7.77e-14
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HTH_XRE | smart00530 | Helix-turn-helix XRE-family like proteins; |
81-133 | 2.66e-10 | ||
Helix-turn-helix XRE-family like proteins; Pssm-ID: 197775 [Multi-domain] Cd Length: 56 Bit Score: 52.52 E-value: 2.66e-10
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HTH_XRE | cd00093 | Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ... |
78-132 | 1.65e-09 | ||
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators. Pssm-ID: 238045 [Multi-domain] Cd Length: 58 Bit Score: 50.63 E-value: 1.65e-09
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HTH_3 | pfam01381 | Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ... |
81-133 | 2.67e-09 | ||
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family. Pssm-ID: 460181 [Multi-domain] Cd Length: 55 Bit Score: 50.23 E-value: 2.67e-09
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Name | Accession | Description | Interval | E-value | ||
MBF1 | pfam08523 | Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 ... |
5-71 | 3.86e-26 | ||
Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif (pfam01381) is found to its C-terminus. Pssm-ID: 462508 Cd Length: 68 Bit Score: 93.46 E-value: 3.86e-26
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aMBF1 | COG1813 | Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ... |
76-132 | 7.77e-14 | ||
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis]; Pssm-ID: 441418 [Multi-domain] Cd Length: 70 Bit Score: 62.26 E-value: 7.77e-14
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HTH_XRE | smart00530 | Helix-turn-helix XRE-family like proteins; |
81-133 | 2.66e-10 | ||
Helix-turn-helix XRE-family like proteins; Pssm-ID: 197775 [Multi-domain] Cd Length: 56 Bit Score: 52.52 E-value: 2.66e-10
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HTH_XRE | cd00093 | Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ... |
78-132 | 1.65e-09 | ||
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators. Pssm-ID: 238045 [Multi-domain] Cd Length: 58 Bit Score: 50.63 E-value: 1.65e-09
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HTH_3 | pfam01381 | Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ... |
81-133 | 2.67e-09 | ||
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family. Pssm-ID: 460181 [Multi-domain] Cd Length: 55 Bit Score: 50.23 E-value: 2.67e-09
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HipB | COG1396 | Transcriptional regulator, contains XRE-family HTH domain [Transcription]; |
71-132 | 2.79e-08 | ||
Transcriptional regulator, contains XRE-family HTH domain [Transcription]; Pssm-ID: 441006 [Multi-domain] Cd Length: 83 Bit Score: 48.07 E-value: 2.79e-08
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XRE | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription]; |
76-132 | 8.65e-07 | ||
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription]; Pssm-ID: 441085 [Multi-domain] Cd Length: 68 Bit Score: 43.68 E-value: 8.65e-07
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COG1709 | COG1709 | Predicted transcriptional regulator,contains XRE-type HTH domain [Transcription]; |
78-128 | 2.17e-05 | ||
Predicted transcriptional regulator,contains XRE-type HTH domain [Transcription]; Pssm-ID: 441315 Cd Length: 234 Bit Score: 42.47 E-value: 2.17e-05
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AF2118 | COG3620 | Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ... |
65-134 | 1.00e-04 | ||
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription]; Pssm-ID: 442838 [Multi-domain] Cd Length: 95 Bit Score: 38.85 E-value: 1.00e-04
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RodZ | COG1426 | Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ... |
75-113 | 2.80e-03 | ||
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 441035 [Multi-domain] Cd Length: 71 Bit Score: 34.39 E-value: 2.80e-03
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YiaG | COG2944 | DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription]; |
81-117 | 9.81e-03 | ||
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription]; Pssm-ID: 442187 [Multi-domain] Cd Length: 64 Bit Score: 32.98 E-value: 9.81e-03
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Blast search parameters | ||||
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