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Conserved domains on  [gi|530380269|ref|XP_005272195|]
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synphilin-1 isoform X4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
322-509 2.14e-22

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 98.49  E-value: 2.14e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 322 ILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLmGEDcLNERNTEKLTPAGLAIKNGQLECV 401
Cdd:COG0666   59 LAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGETPLHLAAYNGNLEIV 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 402 RWMVsetEAIAEL-SCSKDFPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYG 480
Cdd:COG0666  137 KLLL---EAGADVnAQDNDGNTPLHLAAANGNLEIVKLLL----EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209

                        170       180
                 ....*....|....*....|....*....
gi 530380269 481 ANVTMQNHAGEKPSQSAERQGHTLCSRYL 509
Cdd:COG0666  210 ADVNAKDNDGKTALDLAAENGNLEIVKLL 238
SNCAIP_SNCA_bd super family cl25051
Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is ...
 512-555 1.61e-14

Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is responsible for binding to alpha-Synuclein.


The actual alignment was detected with superfamily member pfam16700:

Pssm-ID: 435527  Cd Length: 45  Bit Score: 68.22  E-value: 1.61e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 530380269  512 VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGK 555
Cdd:pfam16700   1 VETCMSLASQVVKLTKQLHEQTAARIAIQKHLQLLFDPQDAEGR 44
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
322-509 2.14e-22

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 98.49  E-value: 2.14e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 322 ILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLmGEDcLNERNTEKLTPAGLAIKNGQLECV 401
Cdd:COG0666   59 LAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGETPLHLAAYNGNLEIV 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 402 RWMVsetEAIAEL-SCSKDFPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYG 480
Cdd:COG0666  137 KLLL---EAGADVnAQDNDGNTPLHLAAANGNLEIVKLLL----EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209

                        170       180
                 ....*....|....*....|....*....
gi 530380269 481 ANVTMQNHAGEKPSQSAERQGHTLCSRYL 509
Cdd:COG0666  210 ADVNAKDNDGKTALDLAAENGNLEIVKLL 238
SNCAIP_SNCA_bd pfam16700
Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is ...
 512-555 1.61e-14

Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is responsible for binding to alpha-Synuclein.


Pssm-ID: 435527  Cd Length: 45  Bit Score: 68.22  E-value: 1.61e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 530380269  512 VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGK 555
Cdd:pfam16700   1 VETCMSLASQVVKLTKQLHEQTAARIAIQKHLQLLFDPQDAEGR 44
Ank_2 pfam12796
Ankyrin repeats (3 copies);
354-487 2.11e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.90  E-value: 2.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269  354 LHIAASQGHAECLQHLTSLMGEdcLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAiaelscskdfpslihyagcygqe 433
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD--ANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV----------------------- 55

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 530380269  434 killwllqfmqeqgisldEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQN 487
Cdd:pfam12796  56 ------------------NLKDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 422-510 3.62e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 44.18  E-value: 3.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 422 SLIHYAGCYGQEKILLWLLQFMQEQGISldevDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQG 501
Cdd:PHA02874 126 TFLHYAIKKGDLESIKMLFEYGADVNIE----DDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYG 201


                 ....*....
gi 530380269 502 HTLCSRYLV 510
Cdd:PHA02874 202 DYACIKLLI 210
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 456-485 1.62e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 36.80  E-value: 1.62e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 530380269   456 DGNSAVHVASQHGYLGCIQTLVEYGANVTM 485
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
322-509 2.14e-22

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 98.49  E-value: 2.14e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 322 ILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLmGEDcLNERNTEKLTPAGLAIKNGQLECV 401
Cdd:COG0666   59 LAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGETPLHLAAYNGNLEIV 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 402 RWMVsetEAIAEL-SCSKDFPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYG 480
Cdd:COG0666  137 KLLL---EAGADVnAQDNDGNTPLHLAAANGNLEIVKLLL----EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209

                        170       180
                 ....*....|....*....|....*....
gi 530380269 481 ANVTMQNHAGEKPSQSAERQGHTLCSRYL 509
Cdd:COG0666  210 ADVNAKDNDGKTALDLAAENGNLEIVKLL 238
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
322-510 1.58e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 81.15  E-value: 1.58e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 322 ILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLtsLMGEDCLNERNTEKLTPAGLAIKNGQLECV 401
Cdd:COG0666   26 LAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLL--LAAGADINAKDDGGNTLLHAAARNGDLEIV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 402 RWMVsetEAIAEL-SCSKDFPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYG 480
Cdd:COG0666  104 KLLL---EAGADVnARDKDGETPLHLAAYNGNLEIVKLLL----EAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAG 176

                        170       180       190
                 ....*....|....*....|....*....|
gi 530380269 481 ANVTMQNHAGEKPSQSAERQGHTLCSRYLV 510
Cdd:COG0666  177 ADVNARDNDGETPLHLAAENGHLEIVKLLL 206
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
322-509 6.34e-15

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 76.53  E-value: 6.34e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 322 ILNIVKEGQISLLPHLAADNLD-KIHDENGNNLLHIAASQGHAECLQHLTSLmGEDcLNERNTEKLTPAGLAIKNGQLEC 400
Cdd:COG0666   91 LHAAARNGDLEIVKLLLEAGADvNARDKDGETPLHLAAYNGNLEIVKLLLEA-GAD-VNAQDNDGNTPLHLAAANGNLEI 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 401 VRWMVsetEAIAEL-SCSKDFPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEY 479
Cdd:COG0666  169 VKLLL---EAGADVnARDNDGETPLHLAAENGHLEIVKLLL----EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241

                        170       180       190
                 ....*....|....*....|....*....|
gi 530380269 480 GANVTMQNHAGEKPSQSAERQGHTLCSRYL 509
Cdd:COG0666  242 GADLNAKDKDGLTALLLAAAAGAALIVKLL 271
SNCAIP_SNCA_bd pfam16700
Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is ...
 512-555 1.61e-14

Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is responsible for binding to alpha-Synuclein.


Pssm-ID: 435527  Cd Length: 45  Bit Score: 68.22  E-value: 1.61e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 530380269  512 VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGK 555
Cdd:pfam16700   1 VETCMSLASQVVKLTKQLHEQTAARIAIQKHLQLLFDPQDAEGR 44
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
337-510 1.59e-11

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 66.13  E-value: 1.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 337 LAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLMGEDCLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSc 416
Cdd:COG0666    6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKD- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 417 sKDFPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQS 496
Cdd:COG0666   85 -DGGNTLLHAAARNGDLEIVKLLL----EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHL 159

                        170
                 ....*....|....
gi 530380269 497 AERQGHTLCSRYLV 510
Cdd:COG0666  160 AAANGNLEIVKLLL 173
Ank_2 pfam12796
Ankyrin repeats (3 copies);
354-487 2.11e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.90  E-value: 2.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269  354 LHIAASQGHAECLQHLTSLMGEdcLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAiaelscskdfpslihyagcygqe 433
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD--ANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV----------------------- 55

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 530380269  434 killwllqfmqeqgisldEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQN 487
Cdd:pfam12796  56 ------------------NLKDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
Ank_2 pfam12796
Ankyrin repeats (3 copies);
326-406 4.63e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 51.66  E-value: 4.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269  326 VKEGQISLLPHLAADNLDK-IHDENGNNLLHIAASQGHAECLQHLTSLMGEDClnerNTEKLTPAGLAIKNGQLECVRWM 404
Cdd:pfam12796   5 AKNGNLELVKLLLENGADAnLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNL----KDNGRTALHYAARSGHLEIVKLL 80


                  ..
gi 530380269  405 VS 406
Cdd:pfam12796  81 LE 82
Ank_4 pfam13637
Ankyrin repeats (many copies);
422-477 9.01e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 43.80  E-value: 9.01e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530380269  422 SLIHYAGCYGQEKILLWLLQFmqeqGISLDEVDQDGNSAVHVASQHGYLGCIQTLV 477
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEK----GADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_4 pfam13637
Ankyrin repeats (many copies);
457-510 1.27e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 40.72  E-value: 1.27e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 530380269  457 GNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLV 510
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 422-510 3.62e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 44.18  E-value: 3.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 422 SLIHYAGCYGQEKILLWLLQFMQEQGISldevDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQG 501
Cdd:PHA02874 126 TFLHYAIKKGDLESIKMLFEYGADVNIE----DDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYG 201


                 ....*....
gi 530380269 502 HTLCSRYLV 510
Cdd:PHA02874 202 DYACIKLLI 210
Ank_4 pfam13637
Ankyrin repeats (many copies);
350-405 5.38e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 38.79  E-value: 5.38e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530380269  350 GNNLLHIAASQGHAECLQHLTSLmGEDClNERNTEKLTPAGLAIKNGQLECVRWMV 405
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEK-GADI-NAVDGNGETALHFAASNGNVEVLKLLL 54
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 445-501 8.66e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 43.35  E-value: 8.66e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530380269 445 EQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQG 501
Cdd:PTZ00322 103 TGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 317-497 1.16e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 42.64  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 317 KKVKSILNI-VKEGQISLLPHLAADNLD-KIHDENGNNLLHIAASQGHAECLQHLtsLMGEDCLNERNTEKLTPAGLAIK 394
Cdd:PHA02874 122 AELKTFLHYaIKKGDLESIKMLFEYGADvNIEDDNGCYPIHIAIKHNFFDIIKLL--LEKGAYANVKDNNGESPLHNAAE 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 395 NGQLECVRWMVSETEAIAeLSCSKDFPSLiHYAGCYGQEKILLWLlqfmqeQGISLDEVDQDGNSAVHVASQHG-YLGCI 473
Cdd:PHA02874 200 YGDYACIKLLIDHGNHIM-NKCKNGFTPL-HNAIIHNRSAIELLI------NNASINDQDIDGSTPLHHAINPPcDIDII 271

                        170       180
                 ....*....|....*....|....
gi 530380269 474 QTLVEYGANVTMQNHAGEKPSQSA 497
Cdd:PHA02874 272 DILLYHKADISIKDNKGENPIDTA 295
Ank_2 pfam12796
Ankyrin repeats (3 copies);
462-510 1.24e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 38.94  E-value: 1.24e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 530380269  462 HVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLV 510
Cdd:pfam12796   2 HLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL 50
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 456-485 1.62e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 36.80  E-value: 1.62e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 530380269   456 DGNSAVHVASQHGYLGCIQTLVEYGANVTM 485
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 378-497 3.95e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 40.72  E-value: 3.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530380269 378 LNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPslIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDG 457
Cdd:PHA02874 117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYP--IHIAIKHNFFDIIKLLL----EKGAYANVKDNNG 190

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 530380269 458 NSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSA 497
Cdd:PHA02874 191 ESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNA 230
Ank_5 pfam13857
Ankyrin repeats (many copies);
347-392 7.11e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 35.79  E-value: 7.11e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 530380269  347 DENGNNLLHIAASQGHAECLQHLtSLMGEDClNERNTEKLTPAGLA 392
Cdd:pfam13857  13 DGEGYTPLHVAAKYGALEIVRVL-LAYGVDL-NLKDEEGLTALDLA 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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