NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|530420667|ref|XP_005261935|]
View 

josephin-1 isoform X1 [Homo sapiens]

Protein Classification

Josephin domain-containing protein( domain architecture ID 10489273)

Josephin domain-containing protein similar to human Josephin-1 that may act as a deubiquitinating enzyme

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Josephin pfam02099
Josephin;
31-173 6.25e-32

Josephin;


:

Pssm-ID: 460444  Cd Length: 154  Bit Score: 113.09  E-value: 6.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530420667   31 QRRELCALHALNNVFQDsNAFTRDTLQEIFQRL-----------SPNTMVTPHK----KSMLGNGNYDVNVIMAALQTKG 95
Cdd:pfam02099   1 QELQLCAQHALNNLLQG-PYFTAVDLADIARQLdeeerslmaegPSADYWTFLSfgssHNVDDSGNFSIQVLEKALEVWG 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530420667   96 YEAVWWDKRRDV-GVIALTNVMGFIMNLpsslcwgplklplkRQHWICVREVGGAYYNLDSKLKMPEWIgGESELRKFL 173
Cdd:pfam02099  80 LELVPWRSPEMQdAKDDPETEVGFICNL--------------SQHWFTIRKFGGQWYNLNSLLKAPELI-SDTYLSAFL 143
 
Name Accession Description Interval E-value
Josephin pfam02099
Josephin;
31-173 6.25e-32

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 113.09  E-value: 6.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530420667   31 QRRELCALHALNNVFQDsNAFTRDTLQEIFQRL-----------SPNTMVTPHK----KSMLGNGNYDVNVIMAALQTKG 95
Cdd:pfam02099   1 QELQLCAQHALNNLLQG-PYFTAVDLADIARQLdeeerslmaegPSADYWTFLSfgssHNVDDSGNFSIQVLEKALEVWG 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530420667   96 YEAVWWDKRRDV-GVIALTNVMGFIMNLpsslcwgplklplkRQHWICVREVGGAYYNLDSKLKMPEWIgGESELRKFL 173
Cdd:pfam02099  80 LELVPWRSPEMQdAKDDPETEVGFICNL--------------SQHWFTIRKFGGQWYNLNSLLKAPELI-SDTYLSAFL 143
 
Name Accession Description Interval E-value
Josephin pfam02099
Josephin;
31-173 6.25e-32

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 113.09  E-value: 6.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530420667   31 QRRELCALHALNNVFQDsNAFTRDTLQEIFQRL-----------SPNTMVTPHK----KSMLGNGNYDVNVIMAALQTKG 95
Cdd:pfam02099   1 QELQLCAQHALNNLLQG-PYFTAVDLADIARQLdeeerslmaegPSADYWTFLSfgssHNVDDSGNFSIQVLEKALEVWG 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530420667   96 YEAVWWDKRRDV-GVIALTNVMGFIMNLpsslcwgplklplkRQHWICVREVGGAYYNLDSKLKMPEWIgGESELRKFL 173
Cdd:pfam02099  80 LELVPWRSPEMQdAKDDPETEVGFICNL--------------SQHWFTIRKFGGQWYNLNSLLKAPELI-SDTYLSAFL 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH