|
Name |
Accession |
Description |
Interval |
E-value |
| CH_GAS2L3 |
cd21269 |
calponin homology (CH) domain found in growth arrest-specific protein 2-like 3; Growth ... |
46-174 |
5.59e-89 |
|
calponin homology (CH) domain found in growth arrest-specific protein 2-like 3; Growth arrest-specific protein 2-like 3 (GAS2L3), also called GAS2-like protein 3, is a cytoskeletal linker protein that may promote and stabilize the formation of the actin and microtubule network. It contains a single copy of the CH domain at the N-terminus. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409118 Cd Length: 130 Bit Score: 273.25 E-value: 5.59e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 46 EATLLPMQEDLSIWLSGLLGFEIKAEKLLDELDNGVLLCQLIDVLQNKVKTCNSEEA-GNFPLRKVPCKKDATSGSFFAR 124
Cdd:cd21269 1 EATLVPMQEDLSIWLSGMLGKEVKAERFMEELDNGVLLCQLIGVLQSKIKECCSTEElKHFPMRKVPCKKDAPSGSFFAR 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 512965415 125 DNTANFLHWCRGIGVDQTYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYG 174
Cdd:cd21269 81 DNTANFLSWCRAIGVDETYLFESEGLVLHKDPRQVCLCLLEIGRIVSRYG 130
|
|
| CH_GAS2 |
cd21267 |
calponin homology (CH) domain found in growth arrest-specific protein 2; Growth ... |
45-177 |
1.22e-64 |
|
calponin homology (CH) domain found in growth arrest-specific protein 2; Growth arrest-specific protein 2 (GAS-2) may play a role in apoptosis by acting as a cell death substrate for caspases. It contains a single copy of the CH domain at the N-terminal region. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409116 Cd Length: 136 Bit Score: 209.80 E-value: 1.22e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 45 HEATLLPMQEDLSIWLSGLLGFEIKAEKLLDELDNGVLLCQLIDVLQNKVKTCNSEE---AGNFPLRKVPCKKDATSGSF 121
Cdd:cd21267 1 HEASLLPMKEDLALWLTNLLGKEITAESFMEKLDNGALLCQLAETLQEKFKENSADAnkpGKSLPVRKIPCRANAPSGSF 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 512965415 122 FARDNTANFLHWCRGIGVDQTYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEP 177
Cdd:cd21267 81 FARDNTANFLSWCRDVGVGDTCLFESEGLVLHKQPREVCLCLLELGRIAARFGVEP 136
|
|
| CH_GAS2-like |
cd21204 |
calponin homology (CH) domain found in the growth arrest-specific protein 2 family; The growth ... |
46-174 |
2.39e-61 |
|
calponin homology (CH) domain found in the growth arrest-specific protein 2 family; The growth arrest-specific protein 2 (GAS-2) family includes GAS-2, and GAS-2 like proteins, GAS2L1-3. GAS-2 may play a role in apoptosis by acting as a cell death substrate for caspases. GAS2L1 (also called GAS2-related protein on chromosome 22 or growth arrest-specific protein 2-like 1) and GAS2L2 (also called GAS2-related protein on chromosome 17 or growth arrest-specific protein 2-like 2) may be involved in the cross-linking of microtubules and microfilaments. GAS2L3, also called GAS2-like protein 3, is a cytoskeletal linker protein that may promote and stabilize the formation of the actin and microtubule network. Members of this family contain a single copy of the CH domain at the N-terminal region. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409053 Cd Length: 131 Bit Score: 200.57 E-value: 2.39e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 46 EATLLPMQEDLSIWLSGLLGFEIKAEKLLDELDNGVLLCQLIDVLQNKVKTCNSEEAGNFPL--RKVPCKKDATSGSFFA 123
Cdd:cd21204 1 EEALLPMKEDLAEWLNDLLGDDLTPDNFLDELRNGVVLCQLAQKIQEAAEKAREAGKKNGPPpsYKLKCNENAKPGSFFA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 512965415 124 RDNTANFLHWCRGIGVDQTYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYG 174
Cdd:cd21204 81 RDNVANFLRWCRKLGVDEVLLFESEDLVLHKNPRQVLLCLLELARIAARYG 131
|
|
| CH_GAS2L1_2 |
cd21268 |
calponin homology (CH) domain found in GAS2-like protein 1 (GAS2L1), GAS2L2, and similar ... |
46-175 |
1.02e-31 |
|
calponin homology (CH) domain found in GAS2-like protein 1 (GAS2L1), GAS2L2, and similar proteins; This subfamily includes GAS2L1 (also called GAS2-related protein on chromosome 22 or growth arrest-specific protein 2-like 1) and GAS2L2 (also called GAS2-related protein on chromosome 17 or growth arrest-specific protein 2-like 2). They may be involved in the cross-linking of microtubules and microfilaments. Members of this subfamily contain a single copy of the CH domain at the N-terminus. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409117 Cd Length: 142 Bit Score: 120.11 E-value: 1.02e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 46 EATLLPMQEDLSIWLSGLLGFEIKAEKLLDELDNGVLLCQLIDVLQNKVKTCNSEEAGNFPLRKVP------CKKDATSG 119
Cdd:cd21268 6 EEYLYAMKEDLAEWLNTLYNLDITADNFFEKLETGVLLCKHANNVTRAAREFQAQHPERASPLKLPprevifYRPSAKPG 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 512965415 120 SFFARDNTANFLHWCRG-IGVDQTYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGV 175
Cdd:cd21268 86 SFQARDNVSNFINWCRQlLGIPEVLLFETDDLVLRKNEKNFVLCLLEVARRGAKFGM 142
|
|
| GAS2 |
pfam02187 |
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members ... |
215-284 |
1.55e-30 |
|
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members and Gas2 family members. The GAR domain comprises around 57 amino acids and has been shown to bind to microtubules.
Pssm-ID: 460480 Cd Length: 69 Bit Score: 114.23 E-value: 1.55e-30
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512965415 215 LHEAVKHIAEDppCSCSHRFSIEYLSEGRYRLGD--KILFIRMLHgKHVMVRVGGGWDTLQGFLLKYDPCRV 284
Cdd:pfam02187 1 LDDEVRRIVAQ--CTCPTKFPVEKVGEGKYRFGDsqKLVFVRILR-SHVMVRVGGGWDTLEEYLLKHDPCRA 69
|
|
| GAS2 |
smart00243 |
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain |
213-286 |
5.14e-28 |
|
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain
Pssm-ID: 128539 Cd Length: 73 Bit Score: 107.15 E-value: 5.14e-28
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 512965415 213 EELHEAVKHIAEDppCSCSHRFSIEYLSEGRYRLGD-KILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRVLQ 286
Cdd:smart00243 1 DKIDDEVKRIVED--CKCPTKFQVEKISEGKYRFGDsQILRLVRILRSTVMVRVGGGWETLDEYLLKHDPCRAKG 73
|
|
| CH_SF |
cd00014 |
calponin homology (CH) domain superfamily; CH domains are actin filament (F-actin) binding ... |
53-168 |
6.65e-16 |
|
calponin homology (CH) domain superfamily; CH domains are actin filament (F-actin) binding motifs, which may be present as a single copy or in tandem repeats (which increase binding affinity). They either function as autonomous actin binding motifs or serve a regulatory function. CH domains are found in cytoskeletal and signal transduction proteins, including actin-binding proteins like spectrin, alpha-actinin, dystrophin, utrophin, and fimbrin, as well as proteins essential for regulation of cell shape (cortexillins), and signaling proteins (Vav).
Pssm-ID: 409031 [Multi-domain] Cd Length: 103 Bit Score: 73.53 E-value: 6.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 53 QEDLSIWLSGLLGFEI--KAEKLLDELDNGVLLCQLIDVLQNKvktcnseeagnfplrKVPCKKDATSGSFFARDNTANF 130
Cdd:cd00014 1 EEELLKWINEVLGEELpvSITDLFESLRDGVLLCKLINKLSPG---------------SIPKINKKPKSPFKKRENINLF 65
|
90 100 110
....*....|....*....|....*....|....*...
gi 512965415 131 LHWCRGIGVDQTYLFESEGLVLHKDPRQVYLCLLEIGR 168
Cdd:cd00014 66 LNACKKLGLPELDLFEPEDLYEKGNLKKVLGTLWALAL 103
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
306-601 |
1.25e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 1.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 306 VPDSPAGTPQPPEM----NPLSAVDRFQKQSLRPGAPLGARSGKEKQARPlRGRPGPAPVGPKFPASRAAPAgpklAPPQ 381
Cdd:PHA03247 2520 LPDEPVGEPVHPRMltwiRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP-PPRPAPRPSEPAVTSRARRPD----APPQ 2594
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 382 GAAP---------SPASSSLAPLHPACKTPASLTFSRSSPSPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPPSPGKRP 452
Cdd:PHA03247 2595 SARPrapvddrgdPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAA 2674
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 453 GSTEPLS--RSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAV-LTPSRKLIPAGK 529
Cdd:PHA03247 2675 QASSPPQrpRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPpAVPAGPATPGGP 2754
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512965415 530 VKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGRTPLSSVSVPQTCARAQSAPKS 601
Cdd:PHA03247 2755 ARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
307-643 |
3.34e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.43 E-value: 3.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPGPAP--VGPKFPASRAAPAGPKLAPPQGAA 384
Cdd:PHA03247 2605 RGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrVSRPRRARRLGRAAQASSPPQRPR 2684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 385 PSPASSSLAPL------HPACKTPAS--LTFSRSSPSPSETLGKCGAAPSRPQAPAL-LTQTPRAPAAAPPSPGKRPGST 455
Cdd:PHA03247 2685 RRAARPTVGSLtsladpPPPPPTPEPapHALVSATPLPPGPAAARQASPALPAAPAPpAVPAGPATPGGPARPARPPTTA 2764
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 456 EPLSRSPVS-------RRRDAPVGSSSKCPRE--PRPKSPLQSSAKMTKPRSHTPATGRGAP--PPGGASQAVLTPSRKL 524
Cdd:PHA03247 2765 GPPAPAPPAapaagppRRLTRPAVASLSESREslPSPWDPADPPAAVLAPAAALPPAASPAGplPPPTSAQPTAPPPPPG 2844
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 525 IPAGKVKQPGSVASAFP-ARAAPGRKETAAVSAARKPPQDKSARPGTGPgSSRPPGRTPLSSVSVPQTCARAQSAPKSAQ 603
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDvRRRPPSRSPAAKPAAPARPPVRRLARPAVSR-STESFALPPDQPERPPQPQAPPPPQPQPQP 2923
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 512965415 604 RAAKGQHWAPGPARGGRSPAAARKPPSPPSPPSPAAGAER 643
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
301-587 |
7.88e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 65.73 E-value: 7.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 301 VSNESVPDSPAGTPQPPEMNPLSAVdrfqkqslrPGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKL--- 377
Cdd:PHA03247 2695 LTSLADPPPPPPTPEPAPHALVSAT---------PLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTtag 2765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 378 -----------APPQGAAPSPASSSLAPLH---PACKTPASLTFSRSSPSPSETLGKCGA------------APSRPQAP 431
Cdd:PHA03247 2766 ppapappaapaAGPPRRLTRPAVASLSESReslPSPWDPADPPAAVLAPAAALPPAASPAgplppptsaqptAPPPPPGP 2845
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 432 ALLTQTPRAPAAAPPSPGKRPGSTEPL------SRSPVSRRRDAPVGSSSKC-----PREPRPKSPLQSSAKMTKPRSHT 500
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDVRRRPPSRSPAakpaapARPPVRRLARPAVSRSTESfalppDQPERPPQPQAPPPPQPQPQPPP 2925
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 501 PATGRGAPPPGGASQAVLTPSRKliPAGKVKQPGSVASAFPARAAPGRKETaavsAARKPPQDKSARPGTGPgSSRPPGR 580
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPPLAPTTD--PAGAGEPSGAVPQPWLGALVPGRVAV----PRFRVPQPAPSREAPAS-STPPLTG 2998
|
....*..
gi 512965415 581 TPLSSVS 587
Cdd:PHA03247 2999 HSLSRVS 3005
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
303-644 |
2.36e-10 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 64.04 E-value: 2.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 303 NESVPDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPgPAPVGPKFPASRAAPAGPKLAPPQG 382
Cdd:PHA03307 65 FEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPP-PTPPPASPPPSPAPDLSEMLRPVGS 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 383 AAPSPASSSLAPLHPACKTPASLTFSRSSPSPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPPSPGK--RPGSTEPLSR 460
Cdd:PHA03307 144 PGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSpiSASASSPAPA 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 461 SPVSRRRDAPVGSSSKC----------PREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAVLTPSRKLIPAGKV 530
Cdd:PHA03307 224 PGRSAADDAGASSSDSSssessgcgwgPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 531 KQPGSVASAFPARAAPGRKE--TAAVSAARKPPQDKSARPGTGPGSSRPPGRTPLSSV---------SVPQTCARAQSAP 599
Cdd:PHA03307 304 GSGPAPSSPRASSSSSSSREssSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADpssprkrprPSRAPSSPAASAG 383
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 512965415 600 KSAQRAAKGQ--HWAPGPARGGRSPAAARKPPSPPSPPSPAAGAERG 644
Cdd:PHA03307 384 RPTRRRARAAvaGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARY 430
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
335-622 |
3.76e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 63.33 E-value: 3.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 335 PGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAAPSPASSSlaplhPACKTPASLTFSRSSPSP 414
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAA-----AAAATRAEAPPAAPAPPA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 415 SetlgkcGAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSrrrdAPVGSSskcprepRPKSPLQSSAKMT 494
Cdd:PRK07003 435 T------ADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSAS----APASDA-------PPDAAFEPAPRAA 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 495 KPRSHTPATGRGAPPPgGASQAVLTPSRKLIPAGKVKQPGSVASAFPARAAPG-------RKETAAVSAARKPPQDKSAR 567
Cdd:PRK07003 498 APSAATPAAVPDARAP-AAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAaaaldvlRNAGMRVSSDRGARAAAAAK 576
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 512965415 568 PGTGPGSSRPPGrTPLSSVSVPQTCARAQSAPKSAQRAAKgqhwAPGPARGGRSP 622
Cdd:PRK07003 577 PAAAPAAAPKPA-APRVAVQVPTPRARAATGDAPPNGAAR----AEQAAESRGAP 626
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
307-650 |
1.39e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 61.73 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQArplrGRPGPAPVGPKFPASRAA-PAGPklAPPQGAAP 385
Cdd:PHA03307 61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPARE----GSPTPPGPSSPDPPPPTPpPASP--PPSPAPDL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 386 SPASSSLAPLHPACKTPASLTFSRSSPSPSetlgkcgAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSR 465
Cdd:PHA03307 135 SEMLRPVGSPGPPPAASPPAAGASPAAVAS-------DAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 466 RRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGgasqavltpSRKLIPAGKVKQPGSVASAFPARAA 545
Cdd:PHA03307 208 RRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPEN---------ECPLPRPAPITLPTRIWEASGWNGP 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 546 PGRKETAAVSAARKPPqDKSARPGTGPGSSRPPGRTPLSSVSVPQTCARAQSAPKSAQRAAKGQHWAPGPARGGR----- 620
Cdd:PHA03307 279 SSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSpsrpp 357
|
330 340 350
....*....|....*....|....*....|....*
gi 512965415 621 -----SPAAARKPPSPPSPPSPAAGAERGDRKPSA 650
Cdd:PHA03307 358 ppadpSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392
|
|
| CH_SCP1-like |
cd21210 |
calponin homology (CH) domain found in Saccharomyces cerevisiae transgelin (SCP1) and similar ... |
52-168 |
3.61e-09 |
|
calponin homology (CH) domain found in Saccharomyces cerevisiae transgelin (SCP1) and similar proteins; The family includes transgelins from Saccharomyces cerevisiae and Schizosaccharomyces pombe, which are also called SCP1 and STG1, respectively. Transgelin, also called calponin homolog 1, has actin-binding and actin-bundling activity. It stabilizes actin filaments against disassembly. Transgelin contains a single copy of the CH domain. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409059 [Multi-domain] Cd Length: 101 Bit Score: 54.30 E-value: 3.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 52 MQEDLSIWLSGLLGFEIKAEKLLDELDNGVLLCQLIdvlqNKVKTCNseeAGNFPLRKVPckkdatsgsFFARDNTANFL 131
Cdd:cd21210 1 AEQEAREWIEEVLGEKLAQGDLLDALKDGVVLCKLA----NRILPAD---IRKYKESKMP---------FVQMENISAFL 64
|
90 100 110
....*....|....*....|....*....|....*..
gi 512965415 132 HWCRGIGVDQTYLFESEGLVLHKDPRQVYLCLLEIGR 168
Cdd:cd21210 65 NAARKLGVPENDLFQTVDLFERKNPAQVLQCLHALSR 101
|
|
| CH_dMP20-like |
cd21207 |
calponin homology (CH) domain found in Drosophila melanogaster muscle-specific protein 20 ... |
59-168 |
5.06e-09 |
|
calponin homology (CH) domain found in Drosophila melanogaster muscle-specific protein 20 (dMP20) and similar domains; This subfamily contains Drosophila melanogaster muscle-specific protein 20 (dMP20), Echinococcus granulosus myophilin, Dictyostelium discoideum Rac guanine nucleotide exchange factor B (also called Trix), and similar proteins. dMP20 is present only in the synchronous muscles of D. melanogaster. It may be involved in the system linking the nerve impulse with the contraction or the relaxation process. Trix is involved in the regulation of the late steps of the endocytic pathway. dMP20 contains a single copy of the CH domain, while Trix (triple CH-domain array exchange factor) contains three, two type 3 CH domains which are included in this model, and one type 1 CH domain that is not included in this subfamily, but is part of the superfamily. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409056 [Multi-domain] Cd Length: 107 Bit Score: 54.24 E-value: 5.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 59 WLSGLLGFEIKAEKLLDE-LDNGVLLCQLIDVLQ-NKVKTCNSeeagnfplrkvpckkdaTSGSFFARDNTANFLHWCRG 136
Cdd:cd21207 13 WIEAVTGEKLDDGKDYEDvLKDGVILCKLINILKpGSVKKINT-----------------SKMAFKLMENIENFLTACKG 75
|
90 100 110
....*....|....*....|....*....|..
gi 512965415 137 IGVDQTYLFESEGLVLHKDPRQVYLCLLEIGR 168
Cdd:cd21207 76 YGVPKTDLFQTVDLYEKKNIPQVTNCLFALGR 107
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
307-651 |
6.97e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 55.76 E-value: 6.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAAPS 386
Cdd:PRK07764 417 PAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAA 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 387 PASSSlAPLHPAcktpASLTFSRSSPSPSETLGKcgaaPSRPQAPALLTQ-----------TPRAPAAAPPSPGKRPGST 455
Cdd:PRK07764 497 PAAPA-APAGAD----DAATLRERWPEILAAVPK----RSRKTWAILLPEatvlgvrgdtlVLGFSTGGLARRFASPGNA 567
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 456 EPL--------------------SRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQ 515
Cdd:PRK07764 568 EVLvtalaeelggdwqveavvgpAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGV 647
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 516 AVLTPSRKLIPAGKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGRTPLSSVSVPQTCARA 595
Cdd:PRK07764 648 AAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQG 727
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 596 QSAPKSA----QRAAKGQHWAPGPARGGRSPAAARKPPSPPSPPSPAAGAERGDRKPSAE 651
Cdd:PRK07764 728 ASAPSPAaddpVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
332-553 |
2.73e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 53.73 E-value: 2.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 332 SLRPG------APLGARSGKEKQARPLRGRPGPAPVGPKFP--ASRAAPAGPKLAPPQGAAPSPASSSLAPLHPACKTPA 403
Cdd:PRK12323 362 AFRPGqsgggaGPATAAAAPVAQPAPAAAAPAAAAPAPAAPpaAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASA 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 404 SLTFSRSSPSPSETlgkcgAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSRRRDAPVGSSSKCPREPRP 483
Cdd:PRK12323 442 RGPGGAPAPAPAPA-----AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDA 516
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 484 KSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAVLTPSRKLIPAGKVKQPGSVASAFPARAAPGRKETAA 553
Cdd:PRK12323 517 APAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAA 586
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
358-627 |
2.76e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.02 E-value: 2.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 358 PAPVGPKFPASRAAPAGPKLAPPQGAAPSPASSSLAPLHPACKTPASltfSRSSPSPSETLGKCGAAPSRPQAPALLTQT 437
Cdd:PHA03307 53 VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPAS---PAREGSPTPPGPSSPDPPPPTPPPASPPPS 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 438 PRAPAAAPPSPGKRPGsteplsrsPVSRRRDAPVGSSSKCPREPrPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAV 517
Cdd:PHA03307 130 PAPDLSEMLRPVGSPG--------PPPAASPPAAGASPAAVASD-AASSRQAALPLSSPEETARAPSSPPAEPPPSTPPA 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 518 LTPSRKLIPAGKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDK-----SARPGTGPGSSRPPGRTPLSSVSVPQTC 592
Cdd:PHA03307 201 AASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCgwgpeNECPLPRPAPITLPTRIWEASGWNGPSS 280
|
250 260 270
....*....|....*....|....*....|....*
gi 512965415 593 aRAQSAPKSAQRAAKGQHWAPGPARGGRSPAAARK 627
Cdd:PHA03307 281 -RPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRA 314
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
346-657 |
3.80e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 53.45 E-value: 3.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 346 EKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAAPSPASSSLAPLHPACKTPASLTfsrsSPSPSETLGKCGAAP 425
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAP----APPSPAGNAPAGGAP 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 426 SRPQAPALLTQtprapaaappspgKRPGSTEPLSRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPA--- 502
Cdd:PRK07764 455 SPPPAAAPSAQ-------------PAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPEila 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 503 ---------------------------------------------------------------TGRGAPPPGGASQAVLT 519
Cdd:PRK07764 522 avpkrsrktwaillpeatvlgvrgdtlvlgfstgglarrfaspgnaevlvtalaeelggdwqvEAVVGPAPGAAGGEGPP 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 520 PSRKLIPAGKVKQPGSV-ASAFPARAAPGrketAAVSAARKPPQDKSARPGTGPGSSRPPGRTPLSSVSVPQTCARAQSA 598
Cdd:PRK07764 602 APASSGPPEEAARPAAPaAPAAPAAPAPA----GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA 677
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 512965415 599 PKSAQRAAKGQHWAPGPARGGRSPAAARKPPSPPSPPSPAAGAERGDRKPSAEKKEGGD 657
Cdd:PRK07764 678 PAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAAD 736
|
|
| CH |
smart00033 |
Calponin homology domain; Actin binding domains present in duplicate at the N-termini of ... |
54-163 |
5.43e-07 |
|
Calponin homology domain; Actin binding domains present in duplicate at the N-termini of spectrin-like proteins (including dystrophin, alpha-actinin). These domains cross-link actin filaments into bundles and networks. A calponin homology domain is predicted in yeasst Cdc24p.
Pssm-ID: 214479 [Multi-domain] Cd Length: 101 Bit Score: 48.08 E-value: 5.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 54 EDLSIWLSGLLG--FEIKAEKLLDELDNGVLLCQLIDVLQNKVktcnseeagnFPLRKVPCKKDAtsgsFFARDNTANFL 131
Cdd:smart00033 1 KTLLRWVNSLLAeyDKPPVTNFSSDLKDGVALCALLNSLSPGL----------VDKKKVAASLSR----FKKIENINLAL 66
|
90 100 110
....*....|....*....|....*....|...
gi 512965415 132 HWCRGIGVDqTYLFESEGLVL-HKDPRQVYLCL 163
Cdd:smart00033 67 SFAEKLGGK-VVLFEPEDLVEgPKLILGVIWTL 98
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
335-625 |
7.87e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 7.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 335 PGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPA--GPKLAP--PQGAAPSP----------------ASSSLAP 394
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSrlAPAILPdePVGEPVHPrmltwirgleelasddAGDPPPP 2554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 395 LHPACKTPA---SLTFSRSSPSPSETLGKCGAA-------PSRPQAP-ALLTQTPRAPAAAPP---------------SP 448
Cdd:PHA03247 2555 LPPAAPPAApdrSVPPPRPAPRPSEPAVTSRARrpdappqSARPRAPvDDRGDPRGPAPPSPLppdthapdppppspsPA 2634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 449 GKRPGSTEPLSRSPVSRRRDAPVGSSSKCPREPRPKS-PLQSSAKMTKPRShtpatgRGAPPPGGASQAVLTPSRKLIPA 527
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRR------RAARPTVGSLTSLADPPPPPPTP 2708
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 528 GKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSA--------RPGTGPGSSRPPGRTPLS--SVSVPQTCARAQS 597
Cdd:PHA03247 2709 EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatpggpaRPARPPTTAGPPAPAPPAapAAGPPRRLTRPAV 2788
|
330 340
....*....|....*....|....*...
gi 512965415 598 APKSAQRAAKGQHWAPGPARGGRSPAAA 625
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAA 2816
|
|
| SCP1 |
COG5199 |
Calponin [Cytoskeleton]; |
53-168 |
1.73e-06 |
|
Calponin [Cytoskeleton];
Pssm-ID: 227526 [Multi-domain] Cd Length: 178 Bit Score: 48.76 E-value: 1.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 53 QEDLSIWLSGLLGFEIKAE-KLLDELDNGVLLCQLIdvlqNKVKTCN-SEEAGNFPlrkvpckkdatsgsFFARDNTANF 130
Cdd:COG5199 15 QKEVTLWIETVLGEKFEPPgDLLSLLKDGVRLCRIL----NEASPLDiKYKESKMP--------------FVQMENISSF 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 512965415 131 LHWCRGIGVDQTYLFESEGLVLHKDPRQVYLCLLEIGR 168
Cdd:COG5199 77 INGLKKLRVPEYELFQTNDLFEAKDLRQVVICLYSLSR 114
|
|
| CH_IQGAP |
cd21206 |
calponin homology (CH) domain found in the IQ motif containing GTPase activating protein ... |
58-163 |
3.47e-06 |
|
calponin homology (CH) domain found in the IQ motif containing GTPase activating protein family; Members of the IQ motif containing GTPase activating protein (IQGAP) family are associated with the Ras GTP-binding protein and act as essential regulators of cytoskeletal function. There are three known IQGAP family members: IQGAP1, IQGAP2, and IQGAP3. They are multi-domain molecules having a calponin-homology (CH) domain which binds F-actin, IQGAP-specific repeats, a single WW domain, four IQ motifs that mediate interactions with calmodulin, and a RasGAP related domain that binds active Rho family GTPases. IQGAP1 negatively regulates Ras family GTPases by stimulating their intrinsic GTPase activity. It lacks GAP activity. Both IQGAP1 and IQGAP2 specifically bind to Cdc42 and Rac1, but not to RhoA. Despite similarities to part of the sequence of RasGAP, neither IQGAP1 nor IQGAP2 interacts with Ras. IQGAP3 regulates the organization of the cytoskeleton under the regulation of Rac1 and Cdc42 in neuronal cells. The depletion of IQGAP3 is shown to impair neurite or axon outgrowth in neuronal cells with disorganized cytoskeleton.
Pssm-ID: 409055 [Multi-domain] Cd Length: 118 Bit Score: 46.45 E-value: 3.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 58 IWLSGLLGFEIKA-EKLLDELDNGVLLCQLIDVLQNKVktcnseeagnfplrkVPCKKDATSG-SFFARDNTANFLHWCR 135
Cdd:cd21206 15 QWIEACLNEELPPtTEFEEELRNGVVLAKLANKFAPKL---------------VPLKKIYDVGlQFRHTDNINHFLRALK 79
|
90 100
....*....|....*....|....*...
gi 512965415 136 GIGVDQTYLFESEGLVLHKDPRQVYLCL 163
Cdd:cd21206 80 KIGLPKIFHFETTDLYEKKNIPKVIYCL 107
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
353-584 |
5.44e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.60 E-value: 5.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 353 RGRPGPAPVGPKFPASRAAPAgpklAPPQGAAPSPASSSLAPLHPACKTPASLTFSRSSPSPSETLGKCGAAPSRPQAPA 432
Cdd:PRK07764 596 GGEGPPAPASSGPPEEAARPA----APAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPA 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 433 LLTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSRRRDAPVGSSSKCPREPRPKsplqssakmtkprshtPATGRGAPPPGG 512
Cdd:PRK07764 672 KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ----------------AAQGASAPSPAA 735
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512965415 513 ASQAVLTPSRKLIPAGKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGRTPLS 584
Cdd:PRK07764 736 DDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAME 807
|
|
| CH |
pfam00307 |
Calponin homology (CH) domain; The CH domain is found in both cytoskeletal proteins and signal ... |
50-168 |
6.44e-06 |
|
Calponin homology (CH) domain; The CH domain is found in both cytoskeletal proteins and signal transduction proteins. The CH domain is involved in actin binding in some members of the family. However in calponins there is evidence that the CH domain is not involved in its actin binding activity. Most member proteins have from two to four copies of the CH domain, however some proteins such as calponin have only a single copy.
Pssm-ID: 425596 [Multi-domain] Cd Length: 109 Bit Score: 45.36 E-value: 6.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 50 LPMQEDLSIWLSGLLGFEIKAEK---LLDELDNGVLLCQLIDVLQnkvktcnseeAGNFPLRKVPCKKdatsgsFFARDN 126
Cdd:pfam00307 1 LELEKELLRWINSHLAEYGPGVRvtnFTTDLRDGLALCALLNKLA----------PGLVDKKKLNKSE------FDKLEN 64
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 512965415 127 TANFLHWCRG-IGVDQtYLFESEGLVlHKDPRQVYLCLLEIGR 168
Cdd:pfam00307 65 INLALDVAEKkLGVPK-VLIEPEDLV-EGDNKSVLTYLASLFR 105
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
293-520 |
2.91e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.18 E-value: 2.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 293 KILAFQKGVSN-----ESVPDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQAR-PLRGRPGPAPVGPKFP 366
Cdd:PRK12323 359 RMLAFRPGQSGggagpATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAaPARRSPAPEALAAARQ 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 367 ASRAAPAGPKlAPPQGAAPSPASSSLAPLHPACKTPASLTfsrSSPSPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPP 446
Cdd:PRK12323 439 ASARGPGGAP-APAPAPAAAPAAAARPAAAGPRPVAAAAA---AAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQP 514
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 512965415 447 SPGKRPGSTEPLSRSPVSRRRDApvgssskcpREPRPKSPLQSSAkmtkPRSHTPATGRGAPPPGGASQAVLTP 520
Cdd:PRK12323 515 DAAPAGWVAESIPDPATADPDDA---------FETLAPAPAAAPA----PRAAAATEPVVAPRPPRASASGLPD 575
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
334-483 |
6.61e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 46.25 E-value: 6.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 334 RPGAPLGARSGKEKQ--ARPLRGRPGPAPvgpkfPASRAAPAGPKLAPPqgAAPSPASSSLAPLHPAcktpasltfsRSS 411
Cdd:PRK14951 365 KPAAAAEAAAPAEKKtpARPEAAAPAAAP-----VAQAAAAPAPAAAPA--AAASAPAAPPAAAPPA----------PVA 427
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512965415 412 PSPSETlgkcgAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTEPlsRSPVSRRRDAPVGSSSKCPREPRP 483
Cdd:PRK14951 428 APAAAA-----PAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAP--EPAVASAAPAPAAAPAAARLTPTE 492
|
|
| CH_LMO7-like |
cd21208 |
calponin homology (CH) domain found in LIM domain only protein 7 and similar proteins; This ... |
59-170 |
6.90e-05 |
|
calponin homology (CH) domain found in LIM domain only protein 7 and similar proteins; This family includes LIM domain only protein 7 (LMO-7) and LIM and calponin homology domains-containing protein 1 (LIMCH1), and similar proteins. LMO-7, also called F-box only protein 20, or LOMP, is a transcription regulator for expression of many Emery-Dreifuss muscular dystrophy (EDMD)-relevant genes. It binds to alpha-actinin and AF6/afadin at adherens junctions for epithelial cell-cell adhesion. LIMCH1 acts as an actin stress fiber-associated protein that activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. It positively regulates actin stress fiber assembly and stabilizes focal adhesions, and therefore negatively regulates cell spreading and cell migration. Members of this family contain a single copy of the CH domain at the N-terminus. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409057 [Multi-domain] Cd Length: 119 Bit Score: 42.71 E-value: 6.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 59 WLSGLLGFEIKAEKLLDELDNGVLLCQLIdvlqNKVKtcnseeagnfplrkvP--CKKDATSGSFFAR-DNTANFLHWCR 135
Cdd:cd21208 8 WIEAVTGKKFPSDDFRESLEDGILLCELI----NAIK---------------PgsIKKINRLPTPIAGlDNLNLFLKACE 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 512965415 136 GIGVDQTYLFES-----------EGLVLHKDP----RQVYLCLLEIGRIV 170
Cdd:cd21208 69 DLGLKDSQLFDPtdlqdlsnrriATHVRKKEDerrlKNVAITLYWLGRAA 118
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
310-622 |
7.24e-05 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 46.20 E-value: 7.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 310 PAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAAPSPAS 389
Cdd:PHA03379 439 SAQVPEPPPVHDLEPGPLHDQHSMAPCPVAQLPPGPLQDLEPGDQLPGVVQDGRPACAPVPAPAGPIVRPWEASLSQVPG 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 390 SSLAPLHPackTPASLTFsrsSPSPSETLGKcgaaPSRPQAPALLTQtprapaaappspgkrpGSTEPLSRSPVSRRRDA 469
Cdd:PHA03379 519 VAFAPVMP---QPMPVEP---VPVPTVALER----PVCPAPPLIAMQ----------------GPGETSGIVRVRERWRP 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 470 PvgssSKCPREPRPKSPLqssakmtkPRSHTPATGRGAPPPGGASQAVLTPSRKLIPAgkvKQPGSVASAFPARAAPGRK 549
Cdd:PHA03379 573 A----PWTPNPPRSPSQM--------SVRDRLARLRAEAQPYQASVEVQPPQLTQVSP---QQPMEYPLEPEQQMFPGSP 637
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512965415 550 ETAAVSAARKPpqdksarpgtGPGSSRPPGRtplssvSVPQTCARAQSAPKSAQRAAKGqhwaPGPARGGRSP 622
Cdd:PHA03379 638 FSQVADVMRAG----------GVPAMQPQYF------DLPLQQPISQGAPLAPLRASMG----PVPPVPATQP 690
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
496-651 |
1.24e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.23 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 496 PRSHTPATGRGAPPPGGASQAVLTPSRkliPAGKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSS 575
Cdd:PRK07003 385 ARAAAAVGASAVPAVTAVTGAAGAALA---PKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADS 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 576 RPPGRTPLSSVSVPQTCARAQSAP-----KSAQRAAKGQHWAPGPARGGRSPAAARKppsppsPPSPAAGAERGDRKPSA 650
Cdd:PRK07003 462 RCDERDAQPPADSGSASAPASDAPpdaafEPAPRAAAPSAATPAAVPDARAPAAASR------EDAPAAAAPPAPEARPP 535
|
.
gi 512965415 651 E 651
Cdd:PRK07003 536 T 536
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
501-654 |
1.80e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.84 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 501 PATGRGAPPPGGASQAVL------TPSRKLIPAGKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGS 574
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAgavpapGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 575 SRPPGRTPLSSVSVPQTCARAQSAPKSAQRAAKGQHWAPGPARGGRSPAAARKPPSPPSPPSPAAGAERGDRKPSAEKKE 654
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
304-530 |
2.62e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.39 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 304 ESVPDSPAGTPQ--PPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPGP--------APVGPKFPASRAAPA 373
Cdd:PHA03307 206 PPRRSSPISASAssPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPitlptriwEASGWNGPSSRPGPA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 374 GPKLAPPqgaAPSPASSSLAPLHPACKTPASLTFSRSSPSPSETlgkcgAAPSRPQAPALLTQTPRAPAAAPPSPGKRPG 453
Cdd:PHA03307 286 SSSSSPR---ERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSS-----SSTSSSSESSRGAAVSPGPSPSRSPSPSRPP 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 454 STEPLSRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPP-----GGASQAVLTPSRKLIPAG 528
Cdd:PHA03307 358 PPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPspldaGAASGAFYARYPLLTPSG 437
|
..
gi 512965415 529 KV 530
Cdd:PHA03307 438 EP 439
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
304-623 |
2.62e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 44.29 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 304 ESVPDSPAGTP---QPPEMNPLSAVDRFQKQSLRPGAP--LGARSGKEKQARPLRGRPGPAPVGPkfpasraapagpklA 378
Cdd:PHA03378 639 QPITFNVLVFPtphQPPQVEITPYKPTWTQIGHIPYQPspTGANTMLPIQWAPGTMQPPPRAPTP--------------M 704
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 379 PPQGAAPSPASSSLAPLHPACKTPASLTFSRSSPSPSETLGKCGAAPSRPQAPalltQTPRAPAAAPPSPGKRPGSTEPL 458
Cdd:PHA03378 705 RPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPP----AAAPGRARPPAAAPGAPTPQPPP 780
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 459 SRSPVSRRRdaPVGSSSKCPREPRPKSPLQSSakmtkPRShtpATGRGAPPPGGASQAVLTPSRKLIPAGKVKQPGSVAS 538
Cdd:PHA03378 781 QAPPAPQQR--PRGAPTPQPPPQAGPTSMQLM-----PRA---APGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQA 850
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 539 AFPARAAPGRKETAAVSAAR--KPPQDKSARPGTGPGSSRPPGRTPLSSVSVPQTCARAQSAPKS------AQRAAKGQH 610
Cdd:PHA03378 851 AAGPTPSPGSGTSDKIVQAPvfYPPVLQPIQVMRQLGSVRAAAASTVTQAPTEYTGERRGVGPMHptdippSKRAKTDAY 930
|
330
....*....|...
gi 512965415 611 WAPGPARGGRSPA 623
Cdd:PHA03378 931 VESQPPHGGQSHS 943
|
|
| CH_LRCH |
cd21205 |
calponin homology (CH) domain found in the leucine-rich repeat and calponin homology ... |
70-166 |
3.18e-04 |
|
calponin homology (CH) domain found in the leucine-rich repeat and calponin homology domain-containing protein family; The leucine-rich repeat and calponin homology domain-containing protein (LRCH) family includes LRCH1-4. LRCH1, also called calponin homology domain-containing protein 1, or neuronal protein 81 (NP81), acts as a negative regulator of GTPase Cdc42 by sequestering Cdc42-guanine exchange factor DOCK8. LRCH2 may play a role in the organization of the cytoskeleton. LRCH3 is part of the DISP complex and may regulate the association of septins with actin and thereby regulate the actin cytoskeleton. LRCH4, also called leucine-rich repeat neuronal protein 4, or leucine-rich neuronal protein, acts as a novel Toll-like receptor (TLR) accessory protein that regulates the innate immune response. Members of this family contain a single copy of the CH domain at the C-terminus. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409054 [Multi-domain] Cd Length: 107 Bit Score: 40.36 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 70 AEKLLDELDNGVLLCQLIDVLQNK-VKTCNSEEAGNFPLRKVPCkkdatsgsffaRDNTANFLHWCRGIGVDQTYLFESE 148
Cdd:cd21205 19 PDDLGEALMDGVVLCHLANHVRPRsVPSIHVPSPAVPKLSMAKC-----------RRNVENFLEACRKLGVPEERLCSPG 87
|
90
....*....|....*...
gi 512965415 149 GLVLHKDPRQVYLCLLEI 166
Cdd:cd21205 88 DILEEKGLVRVAVTVQAL 105
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
293-437 |
3.65e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.55 E-value: 3.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 293 KILAFQKGVSNESVPDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPlgarsgkekqARPLRGRPGPAPVGPKFPASRAAP 372
Cdd:PRK14951 360 RLLAFKPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAA----------APAAAASAPAAPPAAAPPAPVAAP 429
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 512965415 373 AGPKLAPPQGAAPSPASSSLAPLHPACKTPASLTfSRSSPSPSETlgKCGAAPSRPQAPALLTQT 437
Cdd:PRK14951 430 AAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIP-VRVAPEPAVA--SAAPAPAAAPAAARLTPT 491
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
522-657 |
3.98e-04 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 43.74 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 522 RK--LIPAGKVKQPGSVASAF--PARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGRTPLSSVSVPQTCARAQS 597
Cdd:PRK12678 47 RKgeLIAAIKEARGGGAAAAAatPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQ 126
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 598 APKSAQRAAKGQHWAPGPARGGRSPAAARKPPSPPSPPSPAAGAERGDRKPSAEKKEGGD 657
Cdd:PRK12678 127 ARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAE 186
|
|
| CH_CNN1 |
cd21282 |
calponin homology (CH) domain found in calponin-1 and similar proteins; Calponin-1 (CNN1), ... |
53-164 |
7.64e-04 |
|
calponin homology (CH) domain found in calponin-1 and similar proteins; Calponin-1 (CNN1), also called basic calponin, or smooth muscle calponin H1, is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C, and tropomyosin. Calponin-1 contains a single copy of the CH domain. CH domains are actin filament (F-actin) binding motifs.
Pssm-ID: 409131 [Multi-domain] Cd Length: 108 Bit Score: 39.47 E-value: 7.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 53 QEDLSIWLSGLLGFEIkAEKLLDELDNGVLLCQLIDVLQnkvktcnseeAGNFPlrkvpcKKDATSGSFFARDNTANFLH 132
Cdd:cd21282 5 EEELRVWIEGVTGRRI-GDNFMDGLKDGVILCELINKLQ----------PGSVR------KINESTQNWHKLENIGNFIK 67
|
90 100 110
....*....|....*....|....*....|..
gi 512965415 133 WCRGIGVDQTYLFESEGLVLHKDPRQVYLCLL 164
Cdd:cd21282 68 AIMHYGVKPHDIFEANDLFENTNHTQVQSTLI 99
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
356-416 |
1.20e-03 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 41.36 E-value: 1.20e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 512965415 356 PGPAPVGPKFPASRAAPAGPKLAPPQGAAPSPASSSLAPlHPACKTPASLTFSRsSPSPSE 416
Cdd:PLN02983 158 PHAMPPASPPAAQPAPSAPASSPPPTPASPPPAKAPKSS-HPPLKSPMAGTFYR-SPAPGE 216
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
307-521 |
1.54e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGAR--SGKEKQARPLRGRPGPAPVGPKFPASR--AAPAGPKLAPPQG 382
Cdd:PHA03247 2820 PAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvaPGGDVRRRPPSRSPAAKPAAPARPPVRrlARPAVSRSTESFA 2899
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 383 AAPSPASSSLAPLHPACKTPASLTFSRSSPSPSEtlgkcgAAPSRPQAP-ALLTQTPRAPAAAPPSPGKRPGSTEPlSRS 461
Cdd:PHA03247 2900 LPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP------PPPPRPQPPlAPTTDPAGAGEPSGAVPQPWLGALVP-GRV 2972
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 462 PVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAVLTPS 521
Cdd:PHA03247 2973 AVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKQTLWPPD 3032
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
307-503 |
1.77e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.45 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTP---QPPEMNPLSAVDRFQKQSLRPGAPLG-------ARSGKEKQARPLRGRPGPAPVGPkfpasraaPAGPK 376
Cdd:PLN03209 383 PTSPIPTPpssSPASSKSVDAVAKPAEPDVVPSPGSAsnvpevePAQVEAKKTRPLSPYARYEDLKP--------PTSPS 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 377 LAPPQGAAPSPASSSLAPLHPACKTPASLTFSRSSPSPSETlgkcgaaPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTE 456
Cdd:PLN03209 455 PTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMR-------PLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTN 527
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 512965415 457 PLSRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPAT 503
Cdd:PLN03209 528 EVVKVGNSAPPTALADEQHHAQPKPRPLSPYTMYEDLKPPTSPTPSP 574
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
381-627 |
1.89e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.40 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 381 QGAAPSPASSSLAPLH---PACKTPASLTFSRSSPSPSETLGKCGAAPSRPQApalltqtprapaaAPPSPGKRPGSTEP 457
Cdd:PRK12323 368 SGGGAGPATAAAAPVAqpaPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVA-------------AAPARRSPAPEALA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 458 LSRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAVLTPSRKlipagkvKQPGSVA 537
Cdd:PRK12323 435 AARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWE-------ELPPEFA 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 538 SAFPARAAPGRKETAAVSAARKPPQDKSArpgtgpgsSRPPGRTPLSSVSVPQtcARAQSAPKSAQRAAKGQHWAPGPAR 617
Cdd:PRK12323 508 SPAPAQPDAAPAGWVAESIPDPATADPDD--------AFETLAPAPAAAPAPR--AAAATEPVVAPRPPRASASGLPDMF 577
|
250
....*....|
gi 512965415 618 GGRSPAAARK 627
Cdd:PRK12323 578 DGDWPALAAR 587
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
307-627 |
2.18e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 41.21 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQ-SLRPGAPLGARSGKEKQARPLRGRPGPA--------------PVGPKFPASRAA 371
Cdd:PTZ00449 511 PEGPEASGLPPKAPGDKEGEEGEHEdSKESDEPKEGGKPGETKEGEVGKKPGPAkehkpskiptlskkPEFPKDPKHPKD 590
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 372 PAGPKLAP-PQGAA-----PSPASSSLAPLHPACKTPASLTFSRSSPSPSETlgkcgAAPSRPQAPalltqtprapaaap 445
Cdd:PTZ00449 591 PEEPKKPKrPRSAQrptrpKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRP-----SSPERPEGP-------------- 651
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 446 pspgKRPGSteplSRSPvsrrrdapvgSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAVLTPSRKLI 525
Cdd:PTZ00449 652 ----KIIKS----PKPP----------KSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGT 713
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 526 PAGKV-----KQPGSVASAFPARAAPGRKETAAvSAARKPPQDKSARPGTGPGSSRPPGRTPlSSVSVPQTCARAQSAPK 600
Cdd:PTZ00449 714 PFTTPrplppKLPRDEEFPFEPIGDPDAEQPDD-IEFFTPPEEERTFFHETPADTPLPDILA-EEFKEEDIHAETGEPDE 791
|
330 340
....*....|....*....|....*..
gi 512965415 601 SAQRAAKGQHWAPGPArgGRSPAAARK 627
Cdd:PTZ00449 792 AMKRPDSPSEHEDKPP--GDHPSLPKK 816
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
401-610 |
2.28e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 41.44 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 401 TPASLTFSRSSPSPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSRRRdapvGSSSKCPRE 480
Cdd:pfam05109 431 SPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDN----GTESKAPDM 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 481 PRPKSPLQS---SAKMTKPRSHTPATGRGAPPPGGAS--QAVLTPSrkliPAGKVKQPgSVASAFPARAAPGRKETAAVS 555
Cdd:pfam05109 507 TSPTSAVTTptpNATSPTPAVTTPTPNATSPTLGKTSptSAVTTPT----PNATSPTP-AVTTPTPNATIPTLGKTSPTS 581
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 512965415 556 AARKPPQDKSArPGTGPGSsrPPGRTPLSSVSVPQTCARAQSAPKSAQRA-AKGQH 610
Cdd:pfam05109 582 AVTTPTPNATS-PTVGETS--PQANTTNHTLGGTSSTPVVTSPPKNATSAvTTGQH 634
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
532-651 |
2.70e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 532 QPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGRTP--LSSVSVPQTCARAQSAPKSAQRAAKGQ 609
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAParRSPAPEALAAARQASARGPGGAPAPAP 452
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 512965415 610 HWAPGPARGGRSPAAARKPPSPPSPPSPAAGAERGDRKPSAE 651
Cdd:PRK12323 453 APAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADD 494
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
360-606 |
3.18e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 40.67 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 360 PVGPKFPASRAAPA--GPKLAPPQGAAPSPA--SSSLAPLHPacktpasltfsrsSPSPSETLGKCGAAPSRPQAPALLT 435
Cdd:pfam05109 449 PSSTHVPTNLTAPAstGPTVSTADVTSPTPAgtTSGASPVTP-------------SPSPRDNGTESKAPDMTSPTSAVTT 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 436 QTPRAPAAAPPSPGKRPGSTEPL--SRSPVSRRRDAPVGSSSKCP--REPRPKSPLQSSAKMT--------KPRSHTPAT 503
Cdd:pfam05109 516 PTPNATSPTPAVTTPTPNATSPTlgKTSPTSAVTTPTPNATSPTPavTTPTPNATIPTLGKTSptsavttpTPNATSPTV 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 504 GRGAP--------------------PPGGASQAVLTPSRKLIPAGKVK---QPGSVA-------------------SAFP 541
Cdd:pfam05109 596 GETSPqanttnhtlggtsstpvvtsPPKNATSAVTTGQHNITSSSTSSmslRPSSISetlspstsdnstshmplltSAHP 675
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 512965415 542 ------ARAAPGRKETAAVSAARKPPQDKSARPGTGPG---SSRPPGRTPLSSVSVPQTCARAQsAPkSAQRAA 606
Cdd:pfam05109 676 tggeniTQVTPASTSTHHVSTSSPAPRPGTTSQASGPGnssTSTKPGEVNVTKGTPPKNATSPQ-AP-SGQKTA 747
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
501-657 |
3.65e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 40.17 E-value: 3.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 501 PATGR-GAPPPGGASQavLTPSrklipAGKVKQPGSVASAFPARAAPGRKETAAVSAArkPPQDKSARPGTGPGSSRPPG 579
Cdd:PRK12373 181 PQIGRyASEPAGGLTS--LTEE-----AGKARYNASKALAEDIGDTVKRIDGTEVPLL--APWQGDAAPVPPSEAARPKS 251
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 512965415 580 RTPLSSVSVpqtcARAQSAPKSAQRAAKGQHWAPGPARGGRSPAAARKPPSPPSPPSPAAGAErgDRKPSAEKKEGGD 657
Cdd:PRK12373 252 ADAETNAAL----KTPATAPKAAAKNAKAPEAQPVSGTAAAEPAPKEAAKAAAAAAKPALEDK--PRPLGIARPGGAD 323
|
|
| PHA03309 |
PHA03309 |
transcriptional regulator ICP4; Provisional |
403-626 |
4.41e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 165564 [Multi-domain] Cd Length: 2033 Bit Score: 40.61 E-value: 4.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 403 ASLTFSRSSPSPSETLGKCGAAPSRPQAPALltqtprapaaappSPGKRPGSTEPLSRSPVSRRRDAPVGSSSKCPREPR 482
Cdd:PHA03309 1813 AGRSSSSSSSSSSSSSSSPSSRPSRSATPSL-------------SPSPSPPRRAPVDRSRSGRRRERDRPSANPFRWAPR 1879
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 483 PKSPLQSSAKMTKP------RSHTPATGRgapPPGGASQAVLTPSRKLiPAGKVKQPGSVASAFPARAAPGRKET--AAV 554
Cdd:PHA03309 1880 QRSRADHSPDGTAPgdaplnLEDGPGRGR---PIWTPSSATTLPSRSG-PEDSVDETETEDSAPPARLAPSPLETsrAED 1955
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 512965415 555 SAARKPPQDKSARPGTGPGS--SRPPGRTPLSSVSVPQTCARAQSAPKSAQRAAKGQhwaPGPARGGRSPAAAR 626
Cdd:PHA03309 1956 SEDSEYPEYSNPRLGKSPPAlkSREARRPSSKQPRRPSSGKNGHTDVSAASAFFLGR---PAPGSCGRRPLGAR 2026
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
305-416 |
4.47e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 305 SVPDSPAGTPQPPEMNPLSavdRFQKQSLRPGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAA 384
Cdd:PHA03247 364 SLEDLSAGRHHPKRASLPT---RKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEP 440
|
90 100 110
....*....|....*....|....*....|..
gi 512965415 385 PSPASsslaPLHPACKTPASLTFSRSSPSPSE 416
Cdd:PHA03247 441 GSDDG----PAPPPERQPPAPATEPAPDDPDD 468
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
325-394 |
4.84e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 40.11 E-value: 4.84e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512965415 325 VDRFQKqsLRPGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAG--PKLAPPQGAAPSPASSSLAP 394
Cdd:PRK14965 371 LDRLEA--LERGAPAPPSAAWGAPTPAAPAAPPPAAAPPVPPAAPARPAAarPAPAPAPPAAAAPPARSADP 440
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
323-617 |
6.10e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 39.75 E-value: 6.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 323 SAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAAPSPASSSLAPLHPACKTP 402
Cdd:pfam03154 156 SDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTP 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 403 ASLTFSRSSPSPSETlgkcgaaPSRPQAPAllTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSRRRDAP--------VGSS 474
Cdd:pfam03154 236 TLHPQRLPSPHPPLQ-------PMTQPPPP--SQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPpqpfpltpQSSQ 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 475 SKCPREPRPKSPLQSSAkmtkpRSHTPATGRGAPPPGGASQAVLTPSRKLIPagKVKQPGSvaSAFPARAAPGRKETAAV 554
Cdd:pfam03154 307 SQVPPGPSPAAPGQSQQ-----RIHTPPSQSQLQSQQPPREQPLPPAPLSMP--HIKPPPT--TPIPQLPNPQSHKHPPH 377
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512965415 555 SAARKPPQDKSARPgtgpgssRPPGRTPLSSVSvpqTCARAQSAPKSAQRAAKGQHWAPGPAR 617
Cdd:pfam03154 378 LSGPSPFQMNSNLP-------PPPALKPLSSLS---THHPPSAHPPPLQLMPQSQQLPPPPAQ 430
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
454-602 |
6.52e-03 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 39.07 E-value: 6.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 454 STEPLSRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHTPATGRGAPPPGGASQAvltPSRKLIPAGKVKQP 533
Cdd:PHA02682 49 PLDKYSVKEAGRYYQSRLKANSACMQRPSGQSPLAPSPACAAPAPACPACAPAAPAPAVTCPA---PAPACPPATAPTCP 125
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512965415 534 GSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPG---SSRPPGRTPLSSvsvpqtCARAQSAPKSA 602
Cdd:PHA02682 126 PPAVCPAPARPAPACPPSTRQCPPAPPLPTPKPAPAAKPIflhNQLPPPDYPAAS------CPTIETAPAAS 191
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
335-560 |
7.13e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 39.92 E-value: 7.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 335 PGAPLGARSGKEKQARPLRGRPGPAPV-GPKFPASRAAP---------AGPKLA---PPQGAAPSPASSS---------- 391
Cdd:PHA03247 255 PAPPPVVGEGADRAPETARGATGPPPPpEAAAPNGAAAPpdgvwgaalAGAPLAlpaPPDPPPPAPAGDAeeeddedgam 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 392 --LAPL-HPACKTPASLTFSRSSP-SPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTE-PLSRSPVSRR 466
Cdd:PHA03247 335 evVSPLpRPRQHYPLGFPKRRRPTwTPPSSLEDLSAGRHHPKRASLPTRKRRSARHAATPFARGPGGDDqTRPAAPVPAS 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 467 RDAPVGSSSKCPREPRPKSPLQSS--------AKMTKPRSHTPATGRGAPPPGGASQAVLTPSRKLIPA----------- 527
Cdd:PHA03247 415 VPTPAPTPVPASAPPPPATPLPSAepgsddgpAPPPERQPPAPATEPAPDDPDDATRKALDALRERRPPeppgadlaell 494
|
250 260 270
....*....|....*....|....*....|....*...
gi 512965415 528 GKVKQPGSVASAFPARAAPGRKETAA-----VSAARKP 560
Cdd:PHA03247 495 GRHPDTAGTVVRLAAREAAIAREVAEcsrltINALRSP 532
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
307-591 |
8.80e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 39.37 E-value: 8.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPLGARSGKEKQARPLRGRPGP---------APVGPKFPASRAAPAGPKL 377
Cdd:pfam03154 248 PLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPltpqssqsqVPPGPSPAAPGQSQQRIHT 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 378 APPQGAAPSPASSSLAPLhpackTPASLTFSRSSPSPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPPSpgkrPGSTEP 457
Cdd:pfam03154 328 PPSQSQLQSQQPPREQPL-----PPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPP----PPALKP 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 458 LSRSPVSRRRDAPVGSSSKCPREPRPKSPLQSSAKMTKPRSHtPATGRGAPPPGGAsqavltpsrklipagkvkQPGSVA 537
Cdd:pfam03154 399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSL-PPPAASHPPTSGL------------------HQVPSQ 459
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 512965415 538 SAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGrtplSSVSVPQT 591
Cdd:pfam03154 460 SPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVS----SSGPVPAA 509
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
501-646 |
8.89e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 39.31 E-value: 8.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 501 PATGRGAPPPGgASQAVLTPSRKliPAGKVKQPGSVASAFPARAAPGRKETAAVSAARKPPQDKSARPGTGPGSSRPPGR 580
Cdd:PRK14951 366 PAAAAEAAAPA-EKKTPARPEAA--APAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAP 442
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 512965415 581 TPLSSVSVPQtcarAQSAPKSAQRAAKGQhwaPGPArgGRSPAAARkppspPSPPSPAA--GAERGDR 646
Cdd:PRK14951 443 AAVALAPAPP----AQAAPETVAIPVRVA---PEPA--VASAAPAP-----AAAPAAARltPTEEGDV 496
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
307-470 |
9.48e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 39.20 E-value: 9.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 307 PDSPAGTPQPPEMNPLSAVDRFQKQSLRPGAPlGARSGKEKQARPLRGRPGPAPVGPKFPASRAAPAGPKLAPPQGAAPS 386
Cdd:PRK07764 629 PAGAAAAPAEASAAPAPGVAAPEHHPKHVAVP-DASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAA 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512965415 387 PASSSLAPLHPACKTPASLTFSRSSPSPSETLGKCGAAPSRPQAPALLTQTPRAPAAAPPSPGKRPGSTEPLSRSPVSRR 466
Cdd:PRK07764 708 TPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
....
gi 512965415 467 RDAP 470
Cdd:PRK07764 788 DDAP 791
|
|
| |
