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Conserved domains on  [gi|398404027|ref|XP_003853480|]
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uncharacterized protein MYCGRDRAFT_70943 [Zymoseptoria tritici IPO323]

Protein Classification

alpha/beta fold hydrolase domain-containing protein( domain architecture ID 1002311)

alpha/beta fold hydrolase domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hydrolase_4 super family cl38349
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 28-281 2.33e-51

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


The actual alignment was detected with superfamily member pfam12146:

Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 169.32  E-value: 2.33e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   28 TPPIARLIHLHGFSDHAHQHAQFFQYLAsTHAIKVYAFDQRGWGRSvhtPKEKGLSGPTSQVMEDITSFVESLPAEESDI 107
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALA-AQGFAVYAYDHRGHGRS---DGKRGHVPSFDDYVDDLDTFVDKIREEHPGL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  108 PLFLMGHSMGGGECLYYAAMGPaetkRKIRGFIASAPWIAVHEDTrPSFITVAVGRLVGKLFPHRQMVNKVDASKLSRDE 187
Cdd:pfam12146  77 PLFLLGHSMGGLIAALYALRYP----DKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRVPNNLLPDSLSRDP 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  188 EVCKIWHEDEHCHDTGTLEGLAGALDRGGDLET--GKVvvkdgvgeggKTRLFIGFGTADKVVSYTVGRKWFEACKVEDK 265
Cdd:pfam12146 152 EVVAAYAADPLVHGGISARTLYELLDAGERLLRraAAI----------TVPLLLLHGGADRVVDPAGSREFYERAGSTDK 221

                         250
                  ....*....|....*.
gi 398404027  266 EFRAYEGWYHNLDMEP 281
Cdd:pfam12146 222 TLKLYPGLYHELLNEP 237
 
Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 28-281 2.33e-51

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 169.32  E-value: 2.33e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   28 TPPIARLIHLHGFSDHAHQHAQFFQYLAsTHAIKVYAFDQRGWGRSvhtPKEKGLSGPTSQVMEDITSFVESLPAEESDI 107
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALA-AQGFAVYAYDHRGHGRS---DGKRGHVPSFDDYVDDLDTFVDKIREEHPGL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  108 PLFLMGHSMGGGECLYYAAMGPaetkRKIRGFIASAPWIAVHEDTrPSFITVAVGRLVGKLFPHRQMVNKVDASKLSRDE 187
Cdd:pfam12146  77 PLFLLGHSMGGLIAALYALRYP----DKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRVPNNLLPDSLSRDP 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  188 EVCKIWHEDEHCHDTGTLEGLAGALDRGGDLET--GKVvvkdgvgeggKTRLFIGFGTADKVVSYTVGRKWFEACKVEDK 265
Cdd:pfam12146 152 EVVAAYAADPLVHGGISARTLYELLDAGERLLRraAAI----------TVPLLLLHGGADRVVDPAGSREFYERAGSTDK 221

                         250
                  ....*....|....*.
gi 398404027  266 EFRAYEGWYHNLDMEP 281
Cdd:pfam12146 222 TLKLYPGLYHELLNEP 237
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
3-298 2.11e-25

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 100.85  E-value: 2.11e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   3 TSTSGTFTTPDGHSLYTLTYTPPSSTPPIarLIHLHGFSDHAHQHAQFFQYLAStHAIKVYAFDQRGWGRSvhtPKEKGL 82
Cdd:COG2267    2 TRRLVTLPTRDGLRLRGRRWRPAGSPRGT--VVLVHGLGEHSGRYAELAEALAA-AGYAVLAFDLRGHGRS---DGPRGH 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  83 SGPTSQVMEDITSFVESLpAEESDIPLFLMGHSMGGGECLYYAAMGPAetkrKIRGFIASAPWIAVHEDTRPSFitvavg 162
Cdd:COG2267   76 VDSFDDYVDDLRAALDAL-RARPGLPVVLLGHSMGGLIALLYAARYPD----RVAGLVLLAPAYRADPLLGPSA------ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 163 RLVGKLFPHRqmvnkvDASKLsrdeevckiwhedehchdtgtleglagaldrggdletgkvvvkdgvgeggKTRLFIGFG 242
Cdd:COG2267  145 RWLRALRLAE------ALARI--------------------------------------------------DVPVLVLHG 168

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 398404027 243 TADKVVSYTVGRKWFEACKvEDKEFRAYEGWYHNLDMEPGEDKitFANDVAKWVKE 298
Cdd:COG2267  169 GADRVVPPEAARRLAARLS-PDVELVLLPGARHELLNEPAREE--VLAAILAWLER 221
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 2-301 1.29e-19

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 87.52  E-value: 1.29e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   2 ATSTSGTFTTPDGHSLYTLTYTPPSSTPPIARLIHLHGFSDHAHQHAQFFQYLASTHAIKVYAFDQRGWGRSvhtpkeKG 81
Cdd:PLN02298  30 IKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALDLEGHGRS------EG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  82 LSG---PTSQVMEDITSFVESLPAEES--DIPLFLMGHSMGGGECLYYAAMGPAEtkrkIRGFIASAPWIAVHEDTRPSF 156
Cdd:PLN02298 104 LRAyvpNVDLVVEDCLSFFNSVKQREEfqGLPRFLYGESMGGAICLLIHLANPEG----FDGAVLVAPMCKISDKIRPPW 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 157 ITVAVGRLVGKLFPHRQMVNKVD-ASKLSRDEEVCKIWHEDEHCHD----TGTLEGLAGALD----RGGDLETGKVVVKd 227
Cdd:PLN02298 180 PIPQILTFVARFLPTLAIVPTADlLEKSVKVPAKKIIAKRNPMRYNgkprLGTVVELLRVTDylgkKLKDVSIPFIVLH- 258

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398404027 228 gvgeggktrlfigfGTADKVVSYTVGRKWFEACKVEDKEFRAYEGWYHNLDM-EPGEDKITFANDVAKWVKERSG 301
Cdd:PLN02298 259 --------------GSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLFgEPDENIEIVRRDILSWLNERCT 319
 
Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 28-281 2.33e-51

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 169.32  E-value: 2.33e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   28 TPPIARLIHLHGFSDHAHQHAQFFQYLAsTHAIKVYAFDQRGWGRSvhtPKEKGLSGPTSQVMEDITSFVESLPAEESDI 107
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALA-AQGFAVYAYDHRGHGRS---DGKRGHVPSFDDYVDDLDTFVDKIREEHPGL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  108 PLFLMGHSMGGGECLYYAAMGPaetkRKIRGFIASAPWIAVHEDTrPSFITVAVGRLVGKLFPHRQMVNKVDASKLSRDE 187
Cdd:pfam12146  77 PLFLLGHSMGGLIAALYALRYP----DKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRVPNNLLPDSLSRDP 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  188 EVCKIWHEDEHCHDTGTLEGLAGALDRGGDLET--GKVvvkdgvgeggKTRLFIGFGTADKVVSYTVGRKWFEACKVEDK 265
Cdd:pfam12146 152 EVVAAYAADPLVHGGISARTLYELLDAGERLLRraAAI----------TVPLLLLHGGADRVVDPAGSREFYERAGSTDK 221

                         250
                  ....*....|....*.
gi 398404027  266 EFRAYEGWYHNLDMEP 281
Cdd:pfam12146 222 TLKLYPGLYHELLNEP 237
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
3-298 2.11e-25

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 100.85  E-value: 2.11e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   3 TSTSGTFTTPDGHSLYTLTYTPPSSTPPIarLIHLHGFSDHAHQHAQFFQYLAStHAIKVYAFDQRGWGRSvhtPKEKGL 82
Cdd:COG2267    2 TRRLVTLPTRDGLRLRGRRWRPAGSPRGT--VVLVHGLGEHSGRYAELAEALAA-AGYAVLAFDLRGHGRS---DGPRGH 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  83 SGPTSQVMEDITSFVESLpAEESDIPLFLMGHSMGGGECLYYAAMGPAetkrKIRGFIASAPWIAVHEDTRPSFitvavg 162
Cdd:COG2267   76 VDSFDDYVDDLRAALDAL-RARPGLPVVLLGHSMGGLIALLYAARYPD----RVAGLVLLAPAYRADPLLGPSA------ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 163 RLVGKLFPHRqmvnkvDASKLsrdeevckiwhedehchdtgtleglagaldrggdletgkvvvkdgvgeggKTRLFIGFG 242
Cdd:COG2267  145 RWLRALRLAE------ALARI--------------------------------------------------DVPVLVLHG 168

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 398404027 243 TADKVVSYTVGRKWFEACKvEDKEFRAYEGWYHNLDMEPGEDKitFANDVAKWVKE 298
Cdd:COG2267  169 GADRVVPPEAARRLAARLS-PDVELVLLPGARHELLNEPAREE--VLAAILAWLER 221
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 2-301 1.29e-19

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 87.52  E-value: 1.29e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   2 ATSTSGTFTTPDGHSLYTLTYTPPSSTPPIARLIHLHGFSDHAHQHAQFFQYLASTHAIKVYAFDQRGWGRSvhtpkeKG 81
Cdd:PLN02298  30 IKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALDLEGHGRS------EG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  82 LSG---PTSQVMEDITSFVESLPAEES--DIPLFLMGHSMGGGECLYYAAMGPAEtkrkIRGFIASAPWIAVHEDTRPSF 156
Cdd:PLN02298 104 LRAyvpNVDLVVEDCLSFFNSVKQREEfqGLPRFLYGESMGGAICLLIHLANPEG----FDGAVLVAPMCKISDKIRPPW 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 157 ITVAVGRLVGKLFPHRQMVNKVD-ASKLSRDEEVCKIWHEDEHCHD----TGTLEGLAGALD----RGGDLETGKVVVKd 227
Cdd:PLN02298 180 PIPQILTFVARFLPTLAIVPTADlLEKSVKVPAKKIIAKRNPMRYNgkprLGTVVELLRVTDylgkKLKDVSIPFIVLH- 258

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398404027 228 gvgeggktrlfigfGTADKVVSYTVGRKWFEACKVEDKEFRAYEGWYHNLDM-EPGEDKITFANDVAKWVKERSG 301
Cdd:PLN02298 259 --------------GSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLFgEPDENIEIVRRDILSWLNERCT 319
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 8-150 5.94e-14

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 70.33  E-value: 5.94e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   8 TFTTPDGHSLYTLTYTPPSSTPPIARLIHLHGFSDHAHQHAQFFQYLAStHAIKVYAFDQRGWGRSVHTPKEKGLsgPTS 87
Cdd:COG1073   14 TFKSRDGIKLAGDLYLPAGASKKYPAVVVAHGNGGVKEQRALYAQRLAE-LGFNVLAFDYRGYGESEGEPREEGS--PER 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398404027  88 QVMEDITSFVESLPAEESDiPLFLMGHSMGGGECLYYAAMGPaetkrKIRGFIASAPWIAVHE 150
Cdd:COG1073   91 RDARAAVDYLRTLPGVDPE-RIGLLGISLGGGYALNAAATDP-----RVKAVILDSPFTSLED 147
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 25-300 1.05e-12

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 67.86  E-value: 1.05e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  25 PSSTPPIARLIHLHGFSDHAhqhAQFFQYLASTHAIK---VYAFDQRGWGRSvhtpkeKGLSG--PT-----SQVMEDIT 94
Cdd:PLN02385  81 PENSRPKAAVCFCHGYGDTC---TFFFEGIARKIASSgygVFAMDYPGFGLS------EGLHGyiPSfddlvDDVIEHYS 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  95 SFVESlpAEESDIPLFLMGHSMGGGECLYYAAMGPAETKrkirGFIASAPWIAVHEDTRPSFITVAVGRLVGKLFPHRQM 174
Cdd:PLN02385 152 KIKGN--PEFRGLPSFLFGQSMGGAVALKVHLKQPNAWD----GAILVAPMCKIADDVVPPPLVLQILILLANLLPKAKL 225

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 175 VNKVDASKL----SRDEEVCK---IWHEDEHCHDTGtLEGLAGALDRGGDLEtgKVVVKdgvgeggktrLFIGFGTADKV 247
Cdd:PLN02385 226 VPQKDLAELafrdLKKRKMAEynvIAYKDKPRLRTA-VELLRTTQEIEMQLE--EVSLP----------LLILHGEADKV 292

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 398404027 248 VSYTVGRKWFEACKVEDKEFRAYEGWYHN-LDMEPGEDKITFANDVAKWVKERS 300
Cdd:PLN02385 293 TDPSVSKFLYEKASSSDKKLKLYEDAYHSiLEGEPDEMIFQVLDDIISWLDSHS 346
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 34-299 1.88e-12

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 67.23  E-value: 1.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  34 LIHLHGFSDHAHQHAQFFQYLASThAIKVYAFDQRGWGRSvhtpkeKGLSG--PT-SQVMEDITSFVESLPAEESDIPLF 110
Cdd:PLN02652 139 LIIIHGLNEHSGRYLHFAKQLTSC-GFGVYAMDWIGHGGS------DGLHGyvPSlDYVVEDTEAFLEKIRSENPGVPCF 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 111 LMGHSMGGGECLyYAAMGPaETKRKIRGFIASAPWIAVhedtRPSF-ITVAVGRLVGKLFPHRQM--VNKvDASKLSRDE 187
Cdd:PLN02652 212 LFGHSTGGAVVL-KAASYP-SIEDKLEGIVLTSPALRV----KPAHpIVGAVAPIFSLVAPRFQFkgANK-RGIPVSRDP 284

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 188 EVCKIWHEDEHCHdTGTLEGLAG-ALDRGGDLET---GKVVVKdgvgeggktrLFIGFGTADKVVSYTVGRKWFEACKVE 263
Cdd:PLN02652 285 AALLAKYSDPLVY-TGPIRVRTGhEILRISSYLTrnfKSVTVP----------FMVLHGTADRVTDPLASQDLYNEAASR 353

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 398404027 264 DKEFRAYEGWYHNLDMEPGEDKItfANDVAKWVKER 299
Cdd:PLN02652 354 HKDIKLYDGFLHDLLFEPEREEV--GRDIIDWMEKR 387
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
8-154 6.46e-12

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 64.27  E-value: 6.46e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   8 TFTTPDGHSLYTLTYTPPSSTP-PIarLIHLHGF-SDHAHQHAQFFQYLAStHAIKVYAFDQRGWGRSVHTPkekglsgp 85
Cdd:COG1506    1 TFKSADGTTLPGWLYLPADGKKyPV--VVYVHGGpGSRDDSFLPLAQALAS-RGYAVLAPDYRGYGESAGDW-------- 69

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398404027  86 TSQVMEDITSFVESLpAEESDIP---LFLMGHSMGGgeclYYAAMGPAETKRKIRGFIASAP---WIAVHEDTRP 154
Cdd:COG1506   70 GGDEVDDVLAAIDYL-AARPYVDpdrIGIYGHSYGG----YMALLAAARHPDRFKAAVALAGvsdLRSYYGTTRE 139
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 5-147 1.59e-11

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 62.71  E-value: 1.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   5 TSGTFTTPDGHSLYTLTYTPpsSTPPIarLIhLHGFSDHAHQHAQFFQYLASTHaiKVYAFDQRGWGRSVHTPKEKGLSg 84
Cdd:COG0596    2 STPRFVTVDGVRLHYREAGP--DGPPV--VL-LHGLPGSSYEWRPLIPALAAGY--RVIAPDLRGHGRSDKPAGGYTLD- 73

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398404027  85 ptsQVMEDITSFVESLPAEesdiPLFLMGHSMGGGECLYYAAMGPAetkrKIRGFIASAPWIA 147
Cdd:COG0596   74 ---DLADDLAALLDALGLE----RVVLVGHSMGGMVALELAARHPE----RVAGLVLVDEVLA 125
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 34-280 3.46e-10

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 59.44  E-value: 3.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   34 LIHLHGFSDHAHQHAQFFQYLASTHAiKVYAFDQRGWGRSvHTPKEKGlSGPTSQVMEDITSFVESLPAEesdiPLFLMG 113
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGF-RVIALDLRGFGKS-SRPKAQD-DYRTDDLAEDLEYILEALGLE----KVNLVG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  114 HSMGGGECLYYAAMGPaetkRKIRGFIASAPwiavhedTRPSFITVAVGRLVGKLFPH--RQMVNKVDASKLSRDEEVCK 191
Cdd:pfam00561  76 HSMGGLIALAYAAKYP----DRVKALVLLGA-------LDPPHELDEADRFILALFPGffDGFVADFAPNPLGRLVAKLL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  192 IWHEDEHChDTGTLEGLAGALDRGG-DLETGKVVVKDGVGEGGKTRLFIGF------------GTADKVVSYTVGRKWFE 258
Cdd:pfam00561 145 ALLLLRLR-LLKALPLLNKRFPSGDyALAKSLVTGALLFIETWSTELRAKFlgrldeptliiwGDQDPLVPPQALEKLAQ 223

                         250       260
                  ....*....|....*....|..
gi 398404027  259 ACKveDKEFRAYEGWYHNLDME 280
Cdd:pfam00561 224 LFP--NARLVVIPDAGHFAFLE 243
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 34-188 7.60e-07

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 49.01  E-value: 7.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027   34 LIHLHGFSDHAhqhAQFFQYLAstHAIKVYAFDQRGWGRSVHTPkekglsgPTSQVMEDITSFVESLPAEEsdiPLFLMG 113
Cdd:pfam12697   1 VVLVHGAGLSA---APLAALLA--AGVAVLAPDLPGHGSSSPPP-------LDLADLADLAALLDELGAAR---PVVLVG 65

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398404027  114 HSMGGgeclyYAAMGPAETKRKIRGFIASAPWIAVHEDTRPSFITVAVGRLVGKLFPHRQMVNKVDASKLSRDEE 188
Cdd:pfam12697  66 HSLGG-----AVALAAAAAALVVGVLVAPLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAE 135
PHA02857 PHA02857
monoglyceride lipase; Provisional
 27-300 8.05e-07

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 49.50  E-value: 8.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  27 STPPIARLIHLHGFSDHAHQHAQFFQYLASTHaIKVYAFDQRGWGRSvhtPKEKGLSGPTSQVMEDITSFVESLPAEESD 106
Cdd:PHA02857  21 ITYPKALVFISHGAGEHSGRYEELAENISSLG-ILVFSHDHIGHGRS---NGEKMMIDDFGVYVRDVVQHVVTIKSTYPG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 107 IPLFLMGHSMGGGECLYYAAMGPaetkRKIRGFIASAPWIAVHedtRPSFITVAVGRLVGKLFPHRqMVNKVDASKLSRD 186
Cdd:PHA02857  97 VPVFLLGHSMGATISILAAYKNP----NLFTAMILMSPLVNAE---AVPRLNLLAAKLMGIFYPNK-IVGKLCPESVSRD 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 187 EEVCKIWHEDEHCHDTGTLEGLAGALDRGgdleTGKVVVKDgvgEGGKTRLFIGFGTaDKVVSYTVGRKWFEACKVEDKE 266
Cdd:PHA02857 169 MDEVYKYQYDPLVNHEKIKAGFASQVLKA----TNKVRKII---PKIKTPILILQGT-NNEISDVSGAYYFMQHANCNRE 240

                        250       260       270
                 ....*....|....*....|....*....|....
gi 398404027 267 FRAYEGWYHNLDMEPGEDKITFANDVAKWVKERS 300
Cdd:PHA02857 241 IKIYEGAKHHLHKETDEVKKSVMKEIETWIFNRV 274
DUF1749 pfam08538
Protein of unknown function (DUF1749); This is a plant and fungal family of unknown function. ...
 91-144 5.12e-03

Protein of unknown function (DUF1749); This is a plant and fungal family of unknown function. This family contains many hypothetical proteins.


Pssm-ID: 369936  Cd Length: 299  Bit Score: 38.17  E-value: 5.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 398404027   91 EDITSFVESLPAEESDIP----LFLMGHSMGGGECLYYAAMGPAETKRKIRGFIASAP 144
Cdd:pfam08538  85 EEISALVEYLKTTKSGTFgmrkVVLMGHSTGSQDVMYYLTSSNEMGRPKVDGGILQAP 142
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 37-248 6.23e-03

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 38.00  E-value: 6.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027  37 LHGF-SDHAH---QHAQffqyLASthAIKVYAFDQRGWGRSVhtpkeKGLSGPTSQVMED-ITSFVESLPAEESDiplfL 111
Cdd:PRK14875 137 IHGFgGDLNNwlfNHAA----LAA--GRPVIALDLPGHGASS-----KAVGAGSLDELAAaVLAFLDALGIERAH----L 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 112 MGHSMGGGECLYYAAMGPAETKR----------------KIRGFIASA------PWIA--VHEdtrPSFITvavgrlvgk 167
Cdd:PRK14875 202 VGHSMGGAVALRLAARAPQRVASltliapaglgpeingdYIDGFVAAEsrrelkPVLEllFAD---PALVT--------- 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398404027 168 lfphRQMVNkvDASKLSRDEEVckiwhedehchdTGTLEGLAGALDRGGdleTGKVVVKDGVGEGGKTRLFIgFGTADKV 247
Cdd:PRK14875 270 ----RQMVE--DLLKYKRLDGV------------DDALRALADALFAGG---RQRVDLRDRLASLAIPVLVI-WGEQDRI 327


                 .
gi 398404027 248 V 248
Cdd:PRK14875 328 I 328
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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