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Conserved domains on  [gi|328712148|ref|XP_003244738|]
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zinc finger protein 572 [Acyrthosiphon pisum]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
3-192 9.69e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 9.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148   3 RKSYPCDVYAKSFSQSSNLMTHRRTHTG-EKPYACDVCNKSFSQSSNLMAHRRT--HTGE--KPYVCDV--CDKSFSGNH 75
Cdd:COG5048  258 SESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRND 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  76 HLTNHRRTHTGEKPYAC--DVCDKSFSVSGTLTKHQRTH-----TGEKPYACD--ICDKSFAVSGSLTKHRRTHTGEKPY 146
Cdd:COG5048  338 ALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPY 417

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 328712148 147 ACD--VCDKSFSESGTLTKHQRTHTGEKPYACDVCdKSFPVSNHLTNH 192
Cdd:COG5048  418 NCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
172-244 1.06e-04

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.15  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 328712148 172 KPYACDVCDKSFPVSNHLTNHRRTHTGEKPYACDV--CDKSFSVSGTLTKHQRTHTGEKPYACDICDKSFAVSSN 244
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKAS 106
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
3-192 9.69e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 9.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148   3 RKSYPCDVYAKSFSQSSNLMTHRRTHTG-EKPYACDVCNKSFSQSSNLMAHRRT--HTGE--KPYVCDV--CDKSFSGNH 75
Cdd:COG5048  258 SESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRND 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  76 HLTNHRRTHTGEKPYAC--DVCDKSFSVSGTLTKHQRTH-----TGEKPYACD--ICDKSFAVSGSLTKHRRTHTGEKPY 146
Cdd:COG5048  338 ALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPY 417

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 328712148 147 ACD--VCDKSFSESGTLTKHQRTHTGEKPYACDVCdKSFPVSNHLTNH 192
Cdd:COG5048  418 NCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
172-244 1.06e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.15  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 328712148 172 KPYACDVCDKSFPVSNHLTNHRRTHTGEKPYACDV--CDKSFSVSGTLTKHQRTHTGEKPYACDICDKSFAVSSN 244
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKAS 106
zf-H2C2_2 pfam13465
Zinc-finger double domain;
20-45 6.68e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 6.68e-04
                          10        20
                  ....*....|....*....|....*.
gi 328712148   20 NLMTHRRTHTGEKPYACDVCNKSFSQ 45
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
188-212 1.19e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.19e-03
                          10        20
                  ....*....|....*....|....*
gi 328712148  188 HLTNHRRTHTGEKPYACDVCDKSFS 212
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
3-192 9.69e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 9.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148   3 RKSYPCDVYAKSFSQSSNLMTHRRTHTG-EKPYACDVCNKSFSQSSNLMAHRRT--HTGE--KPYVCDV--CDKSFSGNH 75
Cdd:COG5048  258 SESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRND 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  76 HLTNHRRTHTGEKPYAC--DVCDKSFSVSGTLTKHQRTH-----TGEKPYACD--ICDKSFAVSGSLTKHRRTHTGEKPY 146
Cdd:COG5048  338 ALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPY 417

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 328712148 147 ACD--VCDKSFSESGTLTKHQRTHTGEKPYACDVCdKSFPVSNHLTNH 192
Cdd:COG5048  418 NCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
13-240 3.05e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.77  E-value: 3.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  13 KSFSQSSNLMTHRRTHTGEKPYACdvcnksfSQSSNLMAHRRTHTGEKPYVCDVCDKSFSGNHHLTNHRRTHTG-EKPYA 91
Cdd:COG5048  219 NLENSSSSLPLTTNSQLSPKSLLS-------QSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGfSLPIK 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  92 CDVCDKSFSVSGTLTKHQRT--HTGE--KPYACDI--CDKSFAVSGSLTKHRRTHTGEKPYAC--DVCDKSFSESGTLTK 163
Cdd:COG5048  292 SKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEP 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148 164 HQRTH-----TGEKPYACDV--CDKSFPVSNHLTNHRRTHTGEKPYACD--VCDKSFSVSGTLTKHQRTHTGEKPYACDI 234
Cdd:COG5048  372 PQSLQqykdlKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSI 451


                 ....*.
gi 328712148 235 CDKSFA 240
Cdd:COG5048  452 LKSFRR 457
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 114-193 5.70e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 5.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148 114 GEKPYACDI--CDKSFAVSGSLTKHRRT-HtgekpyacdvCDKSFSESGTLTKHQRTHTGEKPYACDVCDKSFPVSNHLT 190
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHMLHgH----------QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                 ...
gi 328712148 191 NHR 193
Cdd:COG5189  416 YHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
172-244 1.06e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.15  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 328712148 172 KPYACDVCDKSFPVSNHLTNHRRTHTGEKPYACDV--CDKSFSVSGTLTKHQRTHTGEKPYACDICDKSFAVSSN 244
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKAS 106
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 30-81 1.31e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 1.31e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 328712148  30 GEKPYACDV--CNKSFSQSSNLMAHR-------RTH------------TGEKPYVCDVCDKSFSGNHHLTNHR 81
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHMlhghqnqKLHenpspekmnifsAKDKPYRCEVCDKRYKNLNGLKYHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
60-141 4.75e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 4.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  60 KPYVCDVCDKSFSGNHHLTNHRRTHTGEKPYACDV--CDKSFSVSGTLTKHQRTHTGEKPYACDICDKSFAVSGSLTKHR 137
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111


                 ....
gi 328712148 138 RTHT 141
Cdd:COG5048  112 SSSS 115
zf-H2C2_2 pfam13465
Zinc-finger double domain;
20-45 6.68e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 6.68e-04
                          10        20
                  ....*....|....*....|....*.
gi 328712148   20 NLMTHRRTHTGEKPYACDVCNKSFSQ 45
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
48-72 6.81e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 6.81e-04
                          10        20
                  ....*....|....*....|....*
gi 328712148   48 NLMAHRRTHTGEKPYVCDVCDKSFS 72
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 170-252 9.60e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 9.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148 170 GEKPYACDV--CDKSFPVSNHLTNHRRtHTGEKPYACDVCDKSfsvsgtltKHQRTHTGEKPYACDICDKSFAVSSNLTA 247
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHML-HGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ....*
gi 328712148 248 HkRRH 252
Cdd:COG5189  417 H-RKH 420
zf-H2C2_2 pfam13465
Zinc-finger double domain;
76-100 1.19e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.19e-03
                          10        20
                  ....*....|....*....|....*
gi 328712148   76 HLTNHRRTHTGEKPYACDVCDKSFS 100
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
188-212 1.19e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.19e-03
                          10        20
                  ....*....|....*....|....*
gi 328712148  188 HLTNHRRTHTGEKPYACDVCDKSFS 212
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
132-156 1.28e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.28e-03
                          10        20
                  ....*....|....*....|....*
gi 328712148  132 SLTKHRRTHTGEKPYACDVCDKSFS 156
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
161-183 1.40e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.40e-03
                          10        20
                  ....*....|....*....|...
gi 328712148  161 LTKHQRTHTGEKPYACDVCDKSF 183
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
105-128 1.42e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.42e-03
                          10        20
                  ....*....|....*....|....
gi 328712148  105 LTKHQRTHTGEKPYACDICDKSFA 128
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
217-240 1.42e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.42e-03
                          10        20
                  ....*....|....*....|....
gi 328712148  217 LTKHQRTHTGEKPYACDICDKSFA 240
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 58-141 6.15e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 37.39  E-value: 6.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328712148  58 GEKPYVCDV--CDKSFSGNHHLTNHRRtHTGEKPYACDVCDKSfsvsgtltKHQRTHTGEKPYACDICDKSFAVSGSLtK 135
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNQNGLKYHML-HGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGL-K 415


                 ....*.
gi 328712148 136 HRRTHT 141
Cdd:COG5189  416 YHRKHS 421
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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