PREDICTED: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [Ailuropoda melanoleuca]
EXPERA domain-containing protein( domain architecture ID 10526086)
EXPERA (EXPanded EBP superfamily) domain-containing protein such as Homo sapiens 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and emopamil-binding protein (EBP)-like may be involved in sterol metabolism or the regulation of cholesterol homeostasis
List of domain hits
Name | Accession | Description | Interval | E-value | |||
EBP | pfam05241 | EXPERA (EXPanded EBP superfamily); The EXPERA (EXPanded EBP superfamily) domain is conserved ... |
96-207 | 4.48e-24 | |||
EXPERA (EXPanded EBP superfamily); The EXPERA (EXPanded EBP superfamily) domain is conserved among the following protein families: TM6SF1 (Transmembrane 6 Superfamily Member 1), TM6SF2 (Transmembrane 6 Superfamily Member 2), MAC30 (Meningioma-associated protein 30 also known as TMEM97, or Transmembrane protein 97), and EBP (Emopamil binding protein). EBP is an enzyme with a D8, D7 sterol isomerase activity that catalyzes the transposition of a double bond from C8=C9 to C7=C8 in the sterol B-ring. Mutations of EBP are known to cause the genetic disorder of X-linked dominant chondrodysplasia punctata (CDPX2). This syndrome of humans is lethal in most males, and affected females display asymmetric hyperkeratotic skin and skeletal abnormalities. : Pssm-ID: 461600 Cd Length: 112 Bit Score: 92.21 E-value: 4.48e-24
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Name | Accession | Description | Interval | E-value | |||
EBP | pfam05241 | EXPERA (EXPanded EBP superfamily); The EXPERA (EXPanded EBP superfamily) domain is conserved ... |
96-207 | 4.48e-24 | |||
EXPERA (EXPanded EBP superfamily); The EXPERA (EXPanded EBP superfamily) domain is conserved among the following protein families: TM6SF1 (Transmembrane 6 Superfamily Member 1), TM6SF2 (Transmembrane 6 Superfamily Member 2), MAC30 (Meningioma-associated protein 30 also known as TMEM97, or Transmembrane protein 97), and EBP (Emopamil binding protein). EBP is an enzyme with a D8, D7 sterol isomerase activity that catalyzes the transposition of a double bond from C8=C9 to C7=C8 in the sterol B-ring. Mutations of EBP are known to cause the genetic disorder of X-linked dominant chondrodysplasia punctata (CDPX2). This syndrome of humans is lethal in most males, and affected females display asymmetric hyperkeratotic skin and skeletal abnormalities. Pssm-ID: 461600 Cd Length: 112 Bit Score: 92.21 E-value: 4.48e-24
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Name | Accession | Description | Interval | E-value | |||
EBP | pfam05241 | EXPERA (EXPanded EBP superfamily); The EXPERA (EXPanded EBP superfamily) domain is conserved ... |
96-207 | 4.48e-24 | |||
EXPERA (EXPanded EBP superfamily); The EXPERA (EXPanded EBP superfamily) domain is conserved among the following protein families: TM6SF1 (Transmembrane 6 Superfamily Member 1), TM6SF2 (Transmembrane 6 Superfamily Member 2), MAC30 (Meningioma-associated protein 30 also known as TMEM97, or Transmembrane protein 97), and EBP (Emopamil binding protein). EBP is an enzyme with a D8, D7 sterol isomerase activity that catalyzes the transposition of a double bond from C8=C9 to C7=C8 in the sterol B-ring. Mutations of EBP are known to cause the genetic disorder of X-linked dominant chondrodysplasia punctata (CDPX2). This syndrome of humans is lethal in most males, and affected females display asymmetric hyperkeratotic skin and skeletal abnormalities. Pssm-ID: 461600 Cd Length: 112 Bit Score: 92.21 E-value: 4.48e-24
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Blast search parameters | ||||
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