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Conserved domains on  [gi|291386325|ref|XP_002709643|]
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sodium-dependent phosphate transporter 1 [Oryctolagus cuniculus]

Protein Classification

inorganic phosphate transporter( domain architecture ID 10475700)

inorganic phosphate transporter is involved in phosphate transport, such as bacterial low-affinity inorganic phosphate transporter and vertebrate sodium-dependent phosphate transporters, which play fundamental housekeeping roles in phosphate transport

Gene Ontology:  GO:0005315|GO:0006817|GO:0016020
TCDB:  2.A.20

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
510-669 7.91e-77

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


:

Pssm-ID: 460184  Cd Length: 322  Bit Score: 248.95  E-value: 7.91e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  510 QDKPEISLLFQFLQILTACFGSFAHGGNDVSNAIGPLV-ALYLVYITGDVSSKMAIPIWLLLYGGIGICIGLWVWGRRVI 588
Cdd:pfam01384 162 KYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRII 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  589 QTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVI 668
Cdd:pfam01384 242 KTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAALL 321

                  .
gi 291386325  669 S 669
Cdd:pfam01384 322 S 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
44-203 4.01e-65

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


:

Pssm-ID: 460184  Cd Length: 322  Bit Score: 217.75  E-value: 4.01e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325   44 GANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMyrnSTQELMAGSVSAMFGSAVWQLV 123
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  124 ASFLKLPISGTHCIVGATIGFSLVARGQDGVKWSELIKIVMSWFISPLLSGIMSGILFFLVRAFILRKADPIPnGLRALP 203
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPLK-ALRLLP 156
 
Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
510-669 7.91e-77

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 248.95  E-value: 7.91e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  510 QDKPEISLLFQFLQILTACFGSFAHGGNDVSNAIGPLV-ALYLVYITGDVSSKMAIPIWLLLYGGIGICIGLWVWGRRVI 588
Cdd:pfam01384 162 KYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRII 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  589 QTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVI 668
Cdd:pfam01384 242 KTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAALL 321

                  .
gi 291386325  669 S 669
Cdd:pfam01384 322 S 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
44-203 4.01e-65

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 217.75  E-value: 4.01e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325   44 GANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMyrnSTQELMAGSVSAMFGSAVWQLV 123
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  124 ASFLKLPISGTHCIVGATIGFSLVARGQDGVKWSELIKIVMSWFISPLLSGIMSGILFFLVRAFILRKADPIPnGLRALP 203
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPLK-ALRLLP 156
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
518-680 1.49e-50

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 178.82  E-value: 1.49e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 518 LFQFLQILTACFGSFAHGGNDVSNAIGPLValyLVYITGDVSSKMAIPIWLLLYGGIGICIGLWVWGRRVIQTMGKDLTP 597
Cdd:COG0306  171 GFRRLQIVSAALMAFSHGANDAQKAMGIIT---LALLAAGLLSGFEVPLWVILLCALAIALGTLLGGWRIIKTLGKKITK 247
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 598 ITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAVMAIFK 677
Cdd:COG0306  248 LDPLQGFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGAARRLSAVRWGVAGRIVLAWVLTLPAAALLAALLYLLLS 327

                 ...
gi 291386325 678 YVI 680
Cdd:COG0306  328 LLG 330
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
26-244 2.87e-45

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 164.18  E-value: 2.87e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  26 LWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYRnstqe 105
Cdd:COG0306    4 LLLLIVVILLALFFDFNNGFHDAANAIATAVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDPGILT----- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 106 lMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVARGQDGVKWSELIKIVMSWFISPLLSGIMSGILFFLVR 185
Cdd:COG0306   79 -LEVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLAAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLLY 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 291386325 186 aFILRKADP--IPNGLRALPVFYAC-------------TIGINLFSIMYTGapLLGFDKLPLWGTILISVGCAV 244
Cdd:COG0306  158 -WLFRRANPrrVNRGFRRLQIVSAAlmafshgandaqkAMGIITLALLAAG--LLSGFEVPLWVILLCALAIAL 228
 
Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
510-669 7.91e-77

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 248.95  E-value: 7.91e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  510 QDKPEISLLFQFLQILTACFGSFAHGGNDVSNAIGPLV-ALYLVYITGDVSSKMAIPIWLLLYGGIGICIGLWVWGRRVI 588
Cdd:pfam01384 162 KYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRII 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  589 QTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVI 668
Cdd:pfam01384 242 KTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAALL 321

                  .
gi 291386325  669 S 669
Cdd:pfam01384 322 S 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
44-203 4.01e-65

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 217.75  E-value: 4.01e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325   44 GANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMyrnSTQELMAGSVSAMFGSAVWQLV 123
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  124 ASFLKLPISGTHCIVGATIGFSLVARGQDGVKWSELIKIVMSWFISPLLSGIMSGILFFLVRAFILRKADPIPnGLRALP 203
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPLK-ALRLLP 156
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
518-680 1.49e-50

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 178.82  E-value: 1.49e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 518 LFQFLQILTACFGSFAHGGNDVSNAIGPLValyLVYITGDVSSKMAIPIWLLLYGGIGICIGLWVWGRRVIQTMGKDLTP 597
Cdd:COG0306  171 GFRRLQIVSAALMAFSHGANDAQKAMGIIT---LALLAAGLLSGFEVPLWVILLCALAIALGTLLGGWRIIKTLGKKITK 247
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 598 ITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAVMAIFK 677
Cdd:COG0306  248 LDPLQGFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGAARRLSAVRWGVAGRIVLAWVLTLPAAALLAALLYLLLS 327

                 ...
gi 291386325 678 YVI 680
Cdd:COG0306  328 LLG 330
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
26-244 2.87e-45

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 164.18  E-value: 2.87e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  26 LWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYRnstqe 105
Cdd:COG0306    4 LLLLIVVILLALFFDFNNGFHDAANAIATAVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDPGILT----- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 106 lMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVARGQDGVKWSELIKIVMSWFISPLLSGIMSGILFFLVR 185
Cdd:COG0306   79 -LEVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLAAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLLY 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 291386325 186 aFILRKADP--IPNGLRALPVFYAC-------------TIGINLFSIMYTGapLLGFDKLPLWGTILISVGCAV 244
Cdd:COG0306  158 -WLFRRANPrrVNRGFRRLQIVSAAlmafshgandaqkAMGIITLALLAAG--LLSGFEVPLWVILLCALAIAL 228
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
535-682 6.53e-20

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 91.41  E-value: 6.53e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  535 GGNDVSNAIGPLVAlylvyiTGDVSSKMAIpiwllLYGGIGICIGLWVWGRRVIQTMGKDLTPITPSSG------FSIEL 608
Cdd:pfam01384   1 GANDVANAFATSVG------SRALTPRQAV-----ILAAIFEFLGAVLLGARVAETIGKGIVDVSFDPGvlmlgmLAALL 69
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 291386325  609 ASALTVVIASNIGLPISTTHCKVGSVVSVGW-LRSKKAVDWRLFRNIFMAWFVTVPISGVISAAVMAIFKYVILR 682
Cdd:pfam01384  70 GAAIWLLIATYLGLPVSSTHALVGALIGAGLaAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILR 144
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
33-188 1.03e-18

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 87.91  E-value: 1.03e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325  33 FIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQAC--------ILASIFETVGSVLLGAKVSETIRKGLIDVEMYRnstq 104
Cdd:COG0306  177 IVSAALMAFSHGANDAQKAMGIITLALLAAGLLSGfevplwviLLCALAIALGTLLGGWRIIKTLGKKITKLDPLQ---- 252
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 105 elmagSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLvARGQDGVKWSELIKIVMSWFISPLLSGIMSGILFFLV 184
Cdd:COG0306  253 -----GFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGA-ARRLSAVRWGVAGRIVLAWVLTLPAAALLAALLYLLL 326

                 ....
gi 291386325 185 RAFI 188
Cdd:COG0306  327 SLLG 330
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
524-683 3.64e-17

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 83.29  E-value: 3.64e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 524 ILTACFGSFAHGGNDVSNAIGPLVAlylvyiTGDVSSKMAIpiwllLYGGIGICIGLWVWGRRVIQTMGKDLTP---ITP 600
Cdd:COG0306   11 ILLALFFDFNNGFHDAANAIATAVG------TRALSPRTAV-----LLAAVFNFLGALLFGTAVAKTIGKGIVDpgiLTL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325 601 SSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGW-LRSKKAVDWRLFRNIFMAWFVTVPISGVISAAVMAIFKYV 679
Cdd:COG0306   80 EVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLaAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLLYWL 159

                 ....
gi 291386325 680 ILRV 683
Cdd:COG0306  160 FRRA 163
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
27-177 4.04e-17

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 82.93  E-value: 4.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325   27 WMLILgfiIAFVLAFSVGANDVANSFG-------TAVGSGVVTLKQAC-----ILASIFETVGSVLLGAKVSETIRKGLI 94
Cdd:pfam01384 173 FLQIL---SAALVSFAHGANDVQNAMGpltaalyAIGTTGEVASKAPVplwvlLLGALAIALGTWTGGWRIIKTVGNKIT 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291386325   95 DVEMYRnstqelmagSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLvARGQDGVKWSELIKIVMSWFISPLLSG 174
Cdd:pfam01384 250 KLTPSR---------GFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGL-ARGLSAVNWGVVGNIVLAWVLTLPVAA 319

                  ...
gi 291386325  175 IMS 177
Cdd:pfam01384 320 LLS 322
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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