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Conserved domains on  [gi|170086798|ref|XP_001874622|]
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uncharacterized protein LACBIDRAFT_321834 [Laccaria bicolor S238N-H82]

Protein Classification

J domain-containing protein( domain architecture ID 1001220)

J domain-containing protein similar to molecular chaperone DnaJ, part of the DnaK-DnaJ-GrpE system, prevents the aggregation of unfolded substrate and acts primarily by stimulating the ATPase activity of Hsp70

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ_bact super family cl37091
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 6-154 6.88e-29

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


The actual alignment was detected with superfamily member TIGR02349:

Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 113.46  E-value: 6.88e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798    6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYGvwpppdlddd 85
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDR---NKDKE----AEEKFKEINEAYEVLSDPEKRAQYDQFG---------- 65

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170086798   86 eplPRRPSGNRRGSFSrhpptPRSPFGDHFFSHpfpsatftdpftlFDSIFGDF--PFQSHSRPSPYRPHR 154
Cdd:TIGR02349  66 ---HAGFNGGGGGGGG-----GFNGFDIGFFGD-------------FGDIFGDFfgGGGGSGRRRRSGPRR 115
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 6-154 6.88e-29

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 113.46  E-value: 6.88e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798    6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYGvwpppdlddd 85
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDR---NKDKE----AEEKFKEINEAYEVLSDPEKRAQYDQFG---------- 65

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170086798   86 eplPRRPSGNRRGSFSrhpptPRSPFGDHFFSHpfpsatftdpftlFDSIFGDF--PFQSHSRPSPYRPHR 154
Cdd:TIGR02349  66 ---HAGFNGGGGGGGG-----GFNGFDIGFFGD-------------FGDIFGDFfgGGGGSGRRRRSGPRR 115
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 4-72 4.51e-26

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 97.93  E-value: 4.51e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 170086798    4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYD 72
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDK-----NPGDPEA-EEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 4-75 2.13e-25

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 98.62  E-value: 2.13e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDR-----NPGDPEA-EEKFKEINEAYEVLSDPEKRAAYDRFG 66
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 6-75 7.33e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 99.83  E-value: 7.33e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK10767   7 YEVLGVSRNASEDEIKKAYRKLAMKYHPDR-----NPGDKEA-EEKFKEIKEAYEVLSDPQKRAAYDQYG 70
DnaJ smart00271
DnaJ molecular chaperone homology domain;
3-67 8.56e-20

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 81.13  E-value: 8.56e-20
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798     3 TNLYEELDLPKDATADQIRKAYKKKALKTHPDRLspnatPEEKAASEEHFRKVNNAYEVLTDPQK 67
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKN-----PGDKEEAEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 4-64 7.57e-19

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 78.36  E-value: 7.57e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRLSPNatpeekAASEEHFRKVNNAYEVLTD 64
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD------PEAEEKFKEINEAYEVLSD 55
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
6-75 1.21e-18

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 85.64  E-value: 1.21e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:NF037946   8 YEVLGVDRDADDQEIKKAFRKLAKKYHPDR---NKAPD----AAEIFAEINEAYEVLSNPEKRANYDKYG 70
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 6-154 6.88e-29

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 113.46  E-value: 6.88e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798    6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYGvwpppdlddd 85
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDR---NKDKE----AEEKFKEINEAYEVLSDPEKRAQYDQFG---------- 65

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170086798   86 eplPRRPSGNRRGSFSrhpptPRSPFGDHFFSHpfpsatftdpftlFDSIFGDF--PFQSHSRPSPYRPHR 154
Cdd:TIGR02349  66 ---HAGFNGGGGGGGG-----GFNGFDIGFFGD-------------FGDIFGDFfgGGGGSGRRRRSGPRR 115
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 4-72 4.51e-26

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 97.93  E-value: 4.51e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 170086798    4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYD 72
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDK-----NPGDPEA-EEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 4-75 2.13e-25

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 98.62  E-value: 2.13e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDR-----NPGDPEA-EEKFKEINEAYEVLSDPEKRAAYDRFG 66
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 6-75 7.33e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 99.83  E-value: 7.33e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK10767   7 YEVLGVSRNASEDEIKKAYRKLAMKYHPDR-----NPGDKEA-EEKFKEIKEAYEVLSDPQKRAAYDQYG 70
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-73 3.63e-21

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 85.93  E-value: 3.63e-21
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAASEEHFRKVNNAYEVLTDPQKRKEYDR 73
Cdd:COG2214    3 DLKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDR-----GGELKALAEELFQRLNEAYEVLSDPERRAEYDR 70
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 1-137 5.10e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 89.47  E-value: 5.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDrlspnATPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYGvwppp 80
Cdd:PRK14277   3 AKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPD-----LNPGDKEA-EQKFKEINEAYEILSDPQKRAQYDQFG----- 71

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 170086798  81 dldddePLPRRPSGNRRGSFSrhpptpRSPFGDHFFSHPFPSatFTDPF-TLFDSIFG 137
Cdd:PRK14277  72 ------HAAFDPGGFGQGGFG------QGGFGGGGFDFDFGG--FGDIFeDIFGDFFG 115
DnaJ smart00271
DnaJ molecular chaperone homology domain;
3-67 8.56e-20

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 81.13  E-value: 8.56e-20
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798     3 TNLYEELDLPKDATADQIRKAYKKKALKTHPDRLspnatPEEKAASEEHFRKVNNAYEVLTDPQK 67
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKN-----PGDKEEAEEKFKEINEAYEVLSDPEK 60
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 6-151 2.55e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 87.16  E-value: 2.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAASEEHFRKVNNAYEVLTDPQKRKEYDRYGVwpppdlddd 85
Cdd:PRK14282   7 YEILGVSRNATQEEIKRAYKRLVKEWHPDR-----HPENRKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGY--------- 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 170086798  86 eplprrpsgnrrgsFSRHPPTPRSPFGDHFFSHPFPSatFTDPFT--LFDSIFGDFPFQSHSRPSPYR 151
Cdd:PRK14282  73 --------------VGEQPPYQETESGGGFFEDIFKD--FENIFNrdIFDIFFGERRTQEEQREYARR 124
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 4-64 7.57e-19

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 78.36  E-value: 7.57e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRLSPNatpeekAASEEHFRKVNNAYEVLTD 64
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD------PEAEEKFKEINEAYEVLSD 55
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
6-75 1.21e-18

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 85.64  E-value: 1.21e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:NF037946   8 YEVLGVDRDADDQEIKKAFRKLAKKYHPDR---NKAPD----AAEIFAEINEAYEVLSNPEKRANYDKYG 70
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 1-75 3.77e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 84.09  E-value: 3.77e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14281   1 MKRDYYEVLGVSRSADKDEIKKAYRKLALKYHPDK-----NPDNKEA-EEHFKEVNEAYEVLSNDDKRRRYDQFG 69
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 1-75 3.99e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 83.74  E-value: 3.99e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 170086798   1 MAT--NLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnatpEEKAASEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14298   1 MATtrDYYEILGLSKDASVEDIKKAYRKLAMKYHPDK-------NKEPDAEEKFKEISEAYAVLSDAEKRAQYDRFG 70
PRK14289 PRK14289
molecular chaperone DnaJ;
6-75 4.30e-18

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 83.73  E-value: 4.30e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14289   8 YEVLGVSKTATVDEIKKAYRKKAIQYHPDK-----NPGDKEA-EEKFKEAAEAYDVLSDPDKRSRYDQFG 71
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 4-70 1.01e-17

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 75.81  E-value: 1.01e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRlspnatPEEKAASEEHFRKVNNAYEVLTDPQKRKE 70
Cdd:COG5407    1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDR------NKGDPKAEERFKEINEAYELLSDAEKRAR 61
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 1-75 1.54e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 82.06  E-value: 1.54e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 170086798   1 MA-TNLYEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPeekaASEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14276   1 MNnTEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDI---NKEP----GAEEKYKEVQEAYETLSDPQKRAAYDQYG 69
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 6-75 1.70e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 82.12  E-value: 1.70e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDrLSPNATPEEKaaseehFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14291   6 YEILGVSRNATQEEIKKAYRRLARKYHPD-FNKNPEAEEK------FKEINEAYQVLSDPEKRKLYDQFG 68
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 3-75 2.56e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 81.43  E-value: 2.56e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 170086798   3 TNLYEELDLPKDATADQIRKAYKKKALKTHPDRLSPNAtpeekaASEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14284   1 MDYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDA------EAEKRFKEVSEAYEVLSDAQKRESYDRYG 67
PRK14297 PRK14297
molecular chaperone DnaJ;
6-75 2.59e-17

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 81.37  E-value: 2.59e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRLSPNATPEEKaaseehFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14297   7 YEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKEAEEK------FKEINEAYQVLSDPQKKAQYDQFG 70
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 6-137 6.00e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 80.32  E-value: 6.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAseEHFRKVNNAYEVLTDPQKRKEYDRYGVwpppdlddd 85
Cdd:PRK14292   5 YELLGVSRTASADEIKSAYRKLALKYHPDR-----NKEKGAA--EKFAQINEAYAVLSDAEKRAHYDRFGT--------- 68

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 170086798  86 eplprrpsgnrrgsfsrhPPTPRSPFGDHFFSHPFpsatftDPFTLFDSIFG 137
Cdd:PRK14292  69 ------------------APGAGMPGGDPFGGMGF------DPMDIFEQLFG 96
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 6-139 6.14e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 80.19  E-value: 6.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYGvwpppdlddd 85
Cdd:PRK14294   7 YEILGVTRDASEEEIKKSYRKLAMKYHPDR-----NPGDKEA-EELFKEAAEAYEVLSDPKKRGIYDQYG---------- 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 170086798  86 eplprrPSGNRRGSFSRhpptprspfgdhffshpfpSATFTDPFTLFDSIFGDF 139
Cdd:PRK14294  71 ------HEGLSGTGFSG-------------------FSGFDDIFSSFGDIFEDF 99
PRK14293 PRK14293
molecular chaperone DnaJ;
1-75 9.37e-17

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 79.65  E-value: 9.37e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDrlsPNATPeekaASEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14293   1 MAADYYEILGVSRDADKDELKRAYRRLARKYHPD---VNKEP----GAEDRFKEINRAYEVLSDPETRARYDQFG 68
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 5-75 1.00e-16

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 79.86  E-value: 1.00e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170086798   5 LYEELDLPKDATADQIRKAYKKKALKTHPDrlspnatpeeKAASEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PTZ00037  30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPD----------KGGDPEKFKEISRAYEVLSDPEKRKIYDEYG 90
PRK14279 PRK14279
molecular chaperone DnaJ;
4-72 1.11e-16

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 79.78  E-value: 1.11e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDrlspnATPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYD 72
Cdd:PRK14279  10 DFYKELGVSSDASAEEIKKAYRKLARELHPD-----ANPGDPAA-EERFKAVSEAHDVLSDPAKRKEYD 72
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 6-75 8.45e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 76.13  E-value: 8.45e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDrlsPNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14299   7 YAILGVPKNASQDEIKKAFKKLARKYHPD---VNKSPG----AEEKFKEINEAYTVLSDPEKRRIYDTYG 69
PRK14295 PRK14295
molecular chaperone DnaJ;
6-72 9.41e-16

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 76.81  E-value: 9.41e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRLSPNatpeekAASEEHFRKVNNAYEVLTDPQKRKEYD 72
Cdd:PRK14295  12 YKVLGVPKDATEAEIKKAYRKLAREYHPDANKGD------AKAEERFKEISEAYDVLSDEKKRKEYD 72
PRK14280 PRK14280
molecular chaperone DnaJ;
6-75 1.29e-15

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 76.30  E-value: 1.29e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDrlspnATPEEKAAseEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14280   7 YEVLGVSKSASKDEIKKAYRKLSKKYHPD-----INKEEGAD--EKFKEISEAYEVLSDDQKRAQYDQFG 69
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 1-75 2.38e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 75.74  E-value: 2.38e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDrlspnATPEEKAASEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14290   1 MAKDYYKILGVDRNASQEDIKKAFRELAKKWHPD-----LHPGNKAEAEEKFKEISEAYEVLSDPQKRRQYDQTG 70
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 1-72 2.79e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 75.47  E-value: 2.79e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDrlspnATPEEKAAseEHFRKVNNAYEVLTDPQKRKEYD 72
Cdd:PRK14278   1 MARDYYGLLGVSRNASDAEIKRAYRKLARELHPD-----VNPDEEAQ--EKFKEISVAYEVLSDPEKRRIVD 65
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 6-139 4.26e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 74.78  E-value: 4.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlSPNaTPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYGvwpppdlddd 85
Cdd:PRK14301   7 YEVLGVSRDASEDEIKKAYRKLALQYHPDR-NPD-NPE----AEQKFKEAAEAYEVLRDAEKRARYDRFG---------- 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 170086798  86 eplprrpsgnrrgsfsrHPPTPRSPFGDHFFSHpfpsatfTDPFTLFDSIFGDF 139
Cdd:PRK14301  71 -----------------HAGVNGNGGFGGFSSA-------EDIFSHFSDIFGDL 100
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
4-69 5.07e-14

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 65.97  E-value: 5.07e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDRLSPNATPEEKAASEEHFRKVNNAYEVLTDPQKRK 69
Cdd:COG1076    5 DAFELLGLPPDADDAELKRAYRKLQREHHPDRLAAGLPEEEQRLALQKAAAINEAYETLKDPRGID 70
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 6-75 5.24e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 71.56  E-value: 5.24e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRLSPNATPEEKaaseehFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14286   7 YDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEK------FKEATEAYEILRDPKKRQAYDQFG 70
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 1-75 1.01e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 70.79  E-value: 1.01e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEEkaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14285   1 MKRDYYEILGLSKGASKDEIKKAYRKIAIKYHPDK---NKGNKE---AESIFKEATEAYEVLIDDNKRAQYDRFG 69
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 6-75 1.24e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 67.54  E-value: 1.24e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDrlspnATPEEKAasEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14283   8 YEVLGVDRNADKKEIKKAYRKLARKYHPD-----VSEEEGA--EEKFKEISEAYAVLSDDEKRQRYDQFG 70
PRK14288 PRK14288
molecular chaperone DnaJ;
1-75 1.24e-11

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 64.71  E-value: 1.24e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEEkaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14288   1 MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDR---NAGDKE---AEEKFKLINEAYGVLSDEKKRALYDRYG 69
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 1-117 1.66e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 64.27  E-value: 1.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   1 MATNLYEELDLPKDATADQIRKAYKKKALKTHPDrlspnaTPEEKAAsEEHFRKVNNAYEVLTDPQKRKEYDRYGvwppp 80
Cdd:PRK14300   1 MSQDYYQILGVSKTASQADLKKAYLKLAKQYHPD------TTDAKDA-EKKFKEINAAYDVLKDEQKRAAYDRFG----- 68

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 170086798  81 dLDDDEPLPRRPSGNRRGSFSrhpPTPRSPFGDhFFS 117
Cdd:PRK14300  69 -HDAFQNQQSRGGGGNHGGFH---PDINDIFGD-FFS 100
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 4-75 4.08e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 63.10  E-value: 4.08e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170086798   4 NLYEELDLPKDATADQIRKAYKKKALKTHPDrlsPNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14287   5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPD---VNKAPD----AEDKFKEVKEAYDTLSDPQKKAHYDQFG 69
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 6-75 7.73e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 59.19  E-value: 7.73e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   6 YEELDLPKDATADQIRKAYKKKALKTHPDRlspNATPEekaaSEEHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PRK14296   7 YEVLGVSKTASEQEIRQAYRKLAKQYHPDL---NKSPD----AHDKMVEINEAADVLLDKDKRKQYDQFG 69
PRK10266 PRK10266
curved DNA-binding protein;
16-147 6.82e-08

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 52.90  E-value: 6.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798  16 TAD--QIRKAYKKKALKTHPD-RLSPNAtpeekaasEEHFRKVNNAYEVLTDPQKRKEYDRygVWPPPDLDDdeplprrp 92
Cdd:PRK10266  15 TDDlkTIKTAYRRLARKYHPDvSKEPDA--------EARFKEVAEAWEVLSDEQRRAEYDQ--LWQHRNDPQ-------- 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 170086798  93 sgnrrgsFSRHPptprspfgDHFFSHPFPSATFTDpftLFDSIFGDFPFQSHSRP 147
Cdd:PRK10266  77 -------FNRQF--------QHGDGQSFNAEDFDD---IFSSIFGQHARQSRQRP 113
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 4-72 1.88e-07

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 51.96  E-value: 1.88e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170086798   4 NLYEELDLPK---DATADQIRKAYKKKALKTHPDRLSPNATPEEKAAseehFRKVNNAYEVLTDPQKRKEYD 72
Cdd:COG5269   44 DLYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAAGGNKGCDEF----FKLIQKAREVLGDRKLRLQYD 111
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 3-75 5.73e-05

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 44.78  E-value: 5.73e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 170086798    3 TNLYEELDLPKDATADQIRKAYKKkalkthpdrLSPNATPEEKAASE--EHFRKVNNAYEVLTDPQKRKEYDRYG 75
Cdd:PTZ00341  573 TLFYDILGVGVNADMKEISERYFK---------LAENYYPPKRSGNEgfHKFKKINEAYQILGDIDKKKMYNKFG 638
hscB PRK01356
co-chaperone HscB; Provisional
 4-71 1.85e-04

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 41.40  E-value: 1.85e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170086798   4 NLYEELDLPKDATAD--QIRKAYKKKALKTHPDRLSpnaTPEEKAASEEHFRKVNNAYEVLTDPQKRKEY 71
Cdd:PRK01356   3 NYFQLLGLPQEYNIDlkILEKQYFAMQVKYHPDKAK---TLQEKEQNLIIASELNNAYSTLKDALKRAEY 69
PHA03102 PHA03102
Small T antigen; Reviewed
 5-68 3.14e-04

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 40.42  E-value: 3.14e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 170086798   5 LYEELDLPKDA--TADQIRKAYKKKALKTHPDrlspnatpeeKAASEEHFRKVNNAYEVLTDPQKR 68
Cdd:PHA03102   7 LMDLLGLPRSAwgNLPLMRKAYLRKCLEFHPD----------KGGDEEKMKELNTLYKKFRESVKS 62
PHA02624 PHA02624
large T antigen; Provisional
 5-64 1.27e-03

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 40.35  E-value: 1.27e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170086798   5 LYEELDLPKDA--TADQIRKAYKKKALKTHPDrlspnatpeeKAASEEHFRKVNNAYEVLTD 64
Cdd:PHA02624  13 LMDLLGLPMAAwgNLPLMRKAYLRKCKEYHPD----------KGGDEEKMKRLNSLYKKLQE 64
hscB PRK05014
co-chaperone HscB; Provisional
 32-71 1.55e-03

co-chaperone HscB; Provisional


Pssm-ID: 179914 [Multi-domain]  Cd Length: 171  Bit Score: 38.74  E-value: 1.55e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 170086798  32 HPDRLSpNATPEEKAASEEHFRKVNNAYEVLTDPQKRKEY 71
Cdd:PRK05014  32 HPDKFA-NASERERLLAVQQAATINDAYQTLKHPLKRAEY 70
hscB PRK00294
co-chaperone HscB; Provisional
 8-71 3.69e-03

co-chaperone HscB; Provisional


Pssm-ID: 166894 [Multi-domain]  Cd Length: 173  Bit Score: 37.52  E-value: 3.69e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 170086798   8 ELDLpkdataDQIRKAYKKKALKTHPDRLSPNATPEEKAASEEHFRkVNNAYEVLTDPQKRKEY 71
Cdd:PRK00294  17 RLDL------DQLATRYRELAREVHPDRFADAPEREQRLALERSAS-LNEAYQTLKSPPRRARY 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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