|
Name |
Accession |
Description |
Interval |
E-value |
| Hydrolase_4 |
pfam12146 |
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ... |
42-279 |
7.35e-101 |
|
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
Pssm-ID: 463473 [Multi-domain] Cd Length: 238 Bit Score: 295.28 E-value: 7.35e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 42 QPKALIFICHGYGDHSKRYSKfLAQALVDEGFFVLSHDHVGHGKSEGERAQIDSLQKYVRDIFDHIDQIIPKYEGLPIYL 121
Cdd:pfam12146 2 EPRAVVVLVHGLGEHSGRYAH-LADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 122 FGHSMGGLIAVLAAQRRPTFFKGVVLSAPALIVDPHKDNKCMRFLGKMVSWVAPSLQLLPAMDPNSMSRDPEQVKAYAED 201
Cdd:pfam12146 81 LGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPILKLLAKLLGKLFPRLRVPNNLLPDSLSRDPEVVAAYAAD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 156346803 202 PLVwHGGVKVGIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERRAGSKDKTIKTYDGYYHDLLKEP 279
Cdd:pfam12146 161 PLV-HGGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLNEP 237
|
|
| PHA02857 |
PHA02857 |
monoglyceride lipase; Provisional |
23-297 |
1.21e-61 |
|
monoglyceride lipase; Provisional
Pssm-ID: 165193 [Multi-domain] Cd Length: 276 Bit Score: 196.65 E-value: 1.21e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 23 FKNKDGLSISTRTWTSqSEQPKALIFICHGYGDHSKRYSKfLAQALVDEGFFVLSHDHVGHGKSEGERAQIDSLQKYVRD 102
Cdd:PHA02857 5 MFNLDNDYIYCKYWKP-ITYPKALVFISHGAGEHSGRYEE-LAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYVRD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 103 IFDHIDQIIPKYEGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPalIVDPHKDNKCMRFLGKMVSWVAPSlQLLPA 182
Cdd:PHA02857 83 VVQHVVTIKSTYPGVPVFLLGHSMGATISILAAYKNPNLFTAMILMSP--LVNAEAVPRLNLLAAKLMGIFYPN-KIVGK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 183 MDPNSMSRDPEQVKAYAEDPLVWHGGVKVGIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERRAGSkD 262
Cdd:PHA02857 160 LCPESVSRDMDEVYKYQYDPLVNHEKIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISDVSGAYYFMQHANC-N 238
|
250 260 270
....*....|....*....|....*....|....*
gi 156346803 263 KTIKTYDGYYHDLLKEPKDDSTVILKDIIEWLNAR 297
Cdd:PHA02857 239 REIKIYEGAKHHLHKETDEVKKSVMKEIETWIFNR 273
|
|
| PldB |
COG2267 |
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism]; |
18-296 |
4.94e-52 |
|
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
Pssm-ID: 441868 [Multi-domain] Cd Length: 221 Bit Score: 170.18 E-value: 4.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 18 ENEGSFKNKDGLSISTRTWTSQsEQPKALIFICHGYGDHSKRYsKFLAQALVDEGFFVLSHDHVGHGKSEGERAQIDSLQ 97
Cdd:COG2267 3 RRLVTLPTRDGLRLRGRRWRPA-GSPRGTVVLVHGLGEHSGRY-AELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 98 KYVRDIfDHIDQIIPKYEGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPALIVDPHkdnkcmrflgkmvswVAPSL 177
Cdd:COG2267 81 DYVDDL-RAALDALRARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPAYRADPL---------------LGPSA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 178 QLLPAMdpnsmsrdpeqvkayaedplvwhggvkvgiglaiahavdEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERR 257
Cdd:COG2267 145 RWLRAL---------------------------------------RLAEALARIDVPVLVLHGGADRVVPPEAARRLAAR 185
|
250 260 270
....*....|....*....|....*....|....*....
gi 156346803 258 AgSKDKTIKTYDGYYHDLLKEPkdDSTVILKDIIEWLNA 296
Cdd:COG2267 186 L-SPDVELVLLPGARHELLNEP--AREEVLAAILAWLER 221
|
|
| PLN02298 |
PLN02298 |
hydrolase, alpha/beta fold family protein |
22-297 |
2.57e-50 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 165939 [Multi-domain] Cd Length: 330 Bit Score: 169.19 E-value: 2.57e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 22 SFKNKDGLSISTRTWT-SQSEQPKALIFICHGYGDHS----KRYSKFLAQAlvdeGFFVLSHDHVGHGKSEGERAQIDSL 96
Cdd:PLN02298 36 FFTSPRGLSLFTRSWLpSSSSPPRALIFMVHGYGNDIswtfQSTAIFLAQM----GFACFALDLEGHGRSEGLRAYVPNV 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 97 QKYVRDI---FDHIDQIiPKYEGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPAL-IVDPHKDNKCMRFLGKMVSW 172
Cdd:PLN02298 112 DLVVEDClsfFNSVKQR-EEFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMCkISDKIRPPWPIPQILTFVAR 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 173 VAPSLQLLPAMDPNSMS-RDPEQVKAYAEDPLVWHGGVKVGIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGS 251
Cdd:PLN02298 191 FLPTLAIVPTADLLEKSvKVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKKLKDVSIPFIVLHGSADVVTDPDVS 270
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 156346803 252 KQLERRAGSKDKTIKTYDGYYHDLL-KEPKDDSTVILKDIIEWLNAR 297
Cdd:PLN02298 271 RALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNER 317
|
|
| PLN02652 |
PLN02652 |
hydrolase; alpha/beta fold family protein |
34-298 |
3.24e-46 |
|
hydrolase; alpha/beta fold family protein
Pssm-ID: 215352 [Multi-domain] Cd Length: 395 Bit Score: 160.06 E-value: 3.24e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 34 RTWTSQSEQPKALIFICHGYGDHSKRYSKFlAQALVDEGFFVLSHDHVGHGKSEGERAQIDSLQKYVRDIFDHIDQIIPK 113
Cdd:PLN02652 126 RSWAPAAGEMRGILIIIHGLNEHSGRYLHF-AKQLTSCGFGVYAMDWIGHGGSDGLHGYVPSLDYVVEDTEAFLEKIRSE 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 114 YEGLPIYLFGHSMGGLIaVLAAQRRPTF---FKGVVLSAPALIVDPHkdNKCMRFLGKMVSWVAPSLQLLPAMDPN-SMS 189
Cdd:PLN02652 205 NPGVPCFLFGHSTGGAV-VLKAASYPSIedkLEGIVLTSPALRVKPA--HPIVGAVAPIFSLVAPRFQFKGANKRGiPVS 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 190 RDPEQVKAYAEDPLVWHGGVKVGIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERRAGSKDKTIKTYD 269
Cdd:PLN02652 282 RDPAALLAKYSDPLVYTGPIRVRTGHEILRISSYLTRNFKSVTVPFMVLHGTADRVTDPLASQDLYNEAASRHKDIKLYD 361
|
250 260
....*....|....*....|....*....
gi 156346803 270 GYYHDLLKEPKDDStvILKDIIEWLNARM 298
Cdd:PLN02652 362 GFLHDLLFEPEREE--VGRDIIDWMEKRL 388
|
|
| PLN02385 |
PLN02385 |
hydrolase; alpha/beta fold family protein |
24-297 |
4.75e-45 |
|
hydrolase; alpha/beta fold family protein
Pssm-ID: 215216 [Multi-domain] Cd Length: 349 Bit Score: 156.07 E-value: 4.75e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 24 KNKDGLSISTRTWTSQSEQPKALIFICHGYGDHSKRYSKFLAQALVDEGFFVLSHDHVGHGKSEGERAQIDSLQKYVRDI 103
Cdd:PLN02385 67 VNSRGVEIFSKSWLPENSRPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDDLVDDV 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 104 FDHIDQII--PKYEGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPAL-IVDPHKDNKCMRFLGKMVSWVAPSLQLL 180
Cdd:PLN02385 147 IEHYSKIKgnPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCkIADDVVPPPLVLQILILLANLLPKAKLV 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 181 PAMDPNSMS-RDPEQVKAYAEDPLVWHGGVKVGIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERRAG 259
Cdd:PLN02385 227 PQKDLAELAfRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFLYEKAS 306
|
250 260 270
....*....|....*....|....*....|....*....
gi 156346803 260 SKDKTIKTYDGYYHDLLK-EPKDDSTVILKDIIEWLNAR 297
Cdd:PLN02385 307 SSDKKLKLYEDAYHSILEgEPDEMIFQVLDDIISWLDSH 345
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
22-295 |
3.32e-26 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 103.17 E-value: 3.32e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 22 SFKNKDGLSISTRTWTSQSEQPKALIFICHGYGDHSKRYSKFLAQALVDEGFFVLSHDHVGHGKSEGERAQIDslqkyVR 101
Cdd:COG1506 1 TFKSADGTTLPGWLYLPADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDE-----VD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 102 DIFDHIDQII--PKYEGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPalIVDphkdnkcMRFLGKMVSWVAPSLQL 179
Cdd:COG1506 76 DVLAAIDYLAarPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAG--VSD-------LRSYYGTTREYTERLMG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 180 LPAMDPnsmsrdpeqvKAYAE-DPLvwhggvkvgiglaiaHAVDEVQAsmesikwPFLVLHGTADTLCLMEGSKQLER-- 256
Cdd:COG1506 147 GPWEDP----------EAYAArSPL---------------AYADKLKT-------PLLLIHGEADDRVPPEQAERLYEal 194
|
250 260 270
....*....|....*....|....*....|....*....
gi 156346803 257 RAGSKDKTIKTYDGYYHDLLKEPKDDstvILKDIIEWLN 295
Cdd:COG1506 195 KKAGKPVELLVYPGEGHGFSGAGAPD---YLERILDFLD 230
|
|
| YvaK |
COG1647 |
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism]; |
43-295 |
4.58e-24 |
|
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 441253 [Multi-domain] Cd Length: 246 Bit Score: 97.70 E-value: 4.58e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 43 PKALIFIcHGYGDHskRYS-KFLAQALVDEGFFVLSHDHVGHGKSEGERAQIdSLQKYVRDIFDHIDQIIPKYEglPIYL 121
Cdd:COG1647 15 RKGVLLL-HGFTGS--PAEmRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKT-TWEDWLEDVEEAYEILKAGYD--KVIV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 122 FGHSMGGLIAVLAAQRRPTfFKGVVLSAPALIVdphkDNKCMRFLGkMVSWVAPSLQLlpamDPNSMSRDPEQVKAYAED 201
Cdd:COG1647 89 IGLSMGGLLALLLAARYPD-VAGLVLLSPALKI----DDPSAPLLP-LLKYLARSLRG----IGSDIEDPEVAEYAYDRT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 202 PLVwhggvkvgIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERRAGSKDKTIKTYDGYYHDLLKEPkd 281
Cdd:COG1647 159 PLR--------ALAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVITLDK-- 228
|
250
....*....|....
gi 156346803 282 DSTVILKDIIEWLN 295
Cdd:COG1647 229 DREEVAEEILDFLE 242
|
|
| FrsA |
COG1073 |
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ... |
15-296 |
1.02e-23 |
|
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain] Cd Length: 253 Bit Score: 96.91 E-value: 1.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 15 PVMENEGSFKNKDGLSISTRTWTSQSEQPK-ALIFICHGYGdHSKRYSKFLAQALVDEGFFVLSHDHVGHGKSEGERAQI 93
Cdd:COG1073 7 KVNKEDVTFKSRDGIKLAGDLYLPAGASKKyPAVVVAHGNG-GVKEQRALYAQRLAELGFNVLAFDYRGYGESEGEPREE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 94 DSLQKY-VRDIFDHIDQiIPKYEGLPIYLFGHSMGGLIAVLAAQRRPTfFKGVVLSAPALIVDPHKDNKCMRFLGKMVSW 172
Cdd:COG1073 86 GSPERRdARAAVDYLRT-LPGVDPERIGLLGISLGGGYALNAAATDPR-VKAVILDSPFTSLEDLAAQRAKEARGAYLPG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 173 VApslqLLPAMDPNSMSRDPeqvkayaedplvwhggvkvgigLAIAHAVDEVQAsmesikwPFLVLHGTADTLCLMEGSK 252
Cdd:COG1073 164 VP----YLPNVRLASLLNDE----------------------FDPLAKIEKISR-------PLLFIHGEKDEAVPFYMSE 210
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 156346803 253 QLERRAgSKDKTIKTYDGYYH-DLLKEPKDdstVILKDIIEWLNA 296
Cdd:COG1073 211 DLYEAA-AEPKELLIVPGAGHvDLYDRPEE---EYFDKLAEFFKK 251
|
|
| MenH |
COG0596 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ... |
27-297 |
4.59e-17 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440361 [Multi-domain] Cd Length: 221 Bit Score: 78.12 E-value: 4.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 27 DGLSISTRTWTsqsEQPKALIFIcHGYGDHSKRYSKFLAqaLVDEGFFVLSHDHVGHGKSEGERAQIdSLQKYVRDIFDH 106
Cdd:COG0596 10 DGVRLHYREAG---PDGPPVVLL-HGLPGSSYEWRPLIP--ALAAGYRVIAPDLRGHGRSDKPAGGY-TLDDLADDLAAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 107 IDQIIPKyeglPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSApalivdphkdnkcmrflgkmvswvapslqllpamdpn 186
Cdd:COG0596 83 LDALGLE----RVVLVGHSMGGMVALELAARHPERVAGLVLVD------------------------------------- 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 187 smsrdpEQVKAYAEDPLVWHGGVKVGIGLAIAHAVDEVQASMESIKWPFLVLHGTADTLCLMEGSKQLERRAgsKDKTIK 266
Cdd:COG0596 122 ------EVLAALAEPLRRPGLAPEALAALLRALARTDLRERLARITVPTLVIWGEKDPIVPPALARRLAELL--PNAELV 193
|
250 260 270
....*....|....*....|....*....|.
gi 156346803 267 TYDGYYHDLlkePKDDSTVILKDIIEWLNAR 297
Cdd:COG0596 194 VLPGAGHFP---PLEQPEAFAAALRDFLARL 221
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
46-278 |
7.42e-17 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 77.93 E-value: 7.42e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 46 LIFICHGYGDHSKRYSKfLAQALVDEGFFVLSHDHVGHGKSEGERAQ----IDSLQKYVRDIFDHIDQIipkyeglPIYL 121
Cdd:pfam00561 2 PVLLLHGLPGSSDLWRK-LAPALARDGFRVIALDLRGFGKSSRPKAQddyrTDDLAEDLEYILEALGLE-------KVNL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 122 FGHSMGGLIAVLAAQRRPTFFKGVVLSAPalIVDPHKDNKCMRFLGKMVSWV-------------APSLQLLPAMDP--- 185
Cdd:pfam00561 74 VGHSMGGLIALAYAAKYPDRVKALVLLGA--LDPPHELDEADRFILALFPGFfdgfvadfapnplGRLVAKLLALLLlrl 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 186 NSMSRDPEQVKAYAEDPLVWHGGVKVGIGLAIAHAVDEVQASME-SIKWPFLVLHGTADTLCLMEGSKQLerRAGSKDKT 264
Cdd:pfam00561 152 RLLKALPLLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLgRLDEPTLIIWGDQDPLVPPQALEKL--AQLFPNAR 229
|
250
....*....|....
gi 156346803 265 IKTYDGYYHDLLKE 278
Cdd:pfam00561 230 LVVIPDAGHFAFLE 243
|
|
| PST-A |
TIGR01607 |
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ... |
22-294 |
2.40e-14 |
|
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.
Pssm-ID: 162444 [Multi-domain] Cd Length: 332 Bit Score: 72.12 E-value: 2.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 22 SFKNKDGLSISTRTWTSQseqpKAL--IFICHGYGDHSK-RYSKFLAQ-------ALVD-----------------EGFF 74
Cdd:TIGR01607 1 SFRNKDGLLLKTYSWIVK----NAIgiIVLIHGLKSHLRlQFLKINAKivnndraVLIDtdnyyiykdswienfnkNGYS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 75 VLSHDHVGHGKSEGE---RAQIDSLQKYVRDIFDHI--------------------DQIIPKYEGLPIYLFGHSMGGLIA 131
Cdd:TIGR01607 77 VYGLDLQGHGESDGLqnlRGHINCFDDLVYDVIQYMnrindsiilenetksddesyDIVNTKENRLPMYIIGLSMGGNIA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 132 V----LAAQRRPTFFKGVV---LSAPALI-------VDPHKDNKCMRFLGKMVSWVAPSLQLLPAMdpnSMSRDPEQVKA 197
Cdd:TIGR01607 157 LrlleLLGKSNENNDKLNIkgcISLSGMIsiksvgsDDSFKFKYFYLPVMNFMSRVFPTFRISKKI---RYEKSPYVNDI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 198 YAEDPLVWHGGVKVGIGLAIAHAVDEVQASMESI--KWPFLVLHGTADTLCLMEGSKQLERRAGSKDKTIKTYDGYYHDL 275
Cdd:TIGR01607 234 IKFDKFRYDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLEDMDHVI 313
|
330
....*....|....*....
gi 156346803 276 LKEPKDDStvILKDIIEWL 294
Cdd:TIGR01607 314 TIEPGNEE--VLKKIIEWI 330
|
|
| YpfH |
COG0400 |
Predicted esterase [General function prediction only]; |
40-166 |
2.83e-11 |
|
Predicted esterase [General function prediction only];
Pssm-ID: 440169 [Multi-domain] Cd Length: 200 Bit Score: 61.46 E-value: 2.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 40 SEQPKALIFICHGYGDHSkRYSKFLAQALVDEGFFVLS------HDHVGHG----KSEGERAQIDSLQKYVRDIFDHIDQ 109
Cdd:COG0400 1 GGPAAPLVVLLHGYGGDE-EDLLPLAPELALPGAAVLAprapvpEGPGGRAwfdlSFLEGREDEEGLAAAAEALAAFIDE 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 156346803 110 IIPKYeGLP---IYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPALI-----VDPHKDNKCMRFL 166
Cdd:COG0400 80 LEARY-GIDperIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPgeealPAPEAALAGTPVF 143
|
|
| PRK10749 |
PRK10749 |
lysophospholipase L2; Provisional |
20-243 |
2.39e-10 |
|
lysophospholipase L2; Provisional
Pssm-ID: 182697 Cd Length: 330 Bit Score: 60.40 E-value: 2.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 20 EGSFKNKDGLSISTRTWTSQseQPKALIFICHGygdHSKRYSKF--LAQALVDEGFFVLSHDHVGHGKS-----EGERAQ 92
Cdd:PRK10749 32 EAEFTGVDDIPIRFVRFRAP--HHDRVVVICPG---RIESYVKYaeLAYDLFHLGYDVLIIDHRGQGRSgrlldDPHRGH 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 93 IDSLQKYVRDIFDHIDQIIPKYEGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPAL-IVDPHKDnkCMrfLGKMVS 171
Cdd:PRK10749 107 VERFNDYVDDLAAFWQQEIQPGPYRKRYALAHSMGGAILTLFLQRHPGVFDAIALCAPMFgIVLPLPS--WM--ARRILN 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 172 WVAPSLQL-------------LP-AMDPNSMSRDPEQ--VKAYAEDPLVWHGG-----VKVGIglaiaHAVDEVQASMES 230
Cdd:PRK10749 183 WAEGHPRIrdgyaigtgrwrpLPfAINVLTHSRERYRrnLRFYADDPELRVGGptyhwVRESI-----LAGEQVLAGAGD 257
|
250
....*....|...
gi 156346803 231 IKWPFLVLHGTAD 243
Cdd:PRK10749 258 ITTPLLLLQAEEE 270
|
|
| DLH |
COG0412 |
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism]; |
16-273 |
5.26e-10 |
|
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440181 [Multi-domain] Cd Length: 226 Bit Score: 58.44 E-value: 5.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 16 VMENEGSFKNKDGLSISTRTWTSQSEQPKALIFICHGYGDHSKRYsKFLAQALVDEGFFVLSHDHVGHGKSEGERAQIDS 95
Cdd:COG0412 1 MTTETVTIPTPDGVTLPGYLARPAGGGPRPGVVVLHEIFGLNPHI-RDVARRLAAAGYVVLAPDLYGRGGPGDDPDEARA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 96 LQ------KYVRDIFDHIDQII--PKYEGLPIYLFGHSMGGLIAVLAAQRRPTfFKGVVlsapalivdphkdnkcmrflg 167
Cdd:COG0412 80 LMgaldpeLLAADLRAALDWLKaqPEVDAGRVGVVGFCFGGGLALLAAARGPD-LAAAV--------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 168 kmvswvapslqllpamdpnsmsrdpeqvkayaedplVWHGGVkvgiglaiahAVDEVQASMESIKWPFLVLHGTADTLCL 247
Cdd:COG0412 138 ------------------------------------SFYGGL----------PADDLLDLAARIKAPVLLLYGEKDPLVP 171
|
250 260
....*....|....*....|....*...
gi 156346803 248 MEGSKQLER--RAGSKDKTIKTYDGYYH 273
Cdd:COG0412 172 PEQVAALEAalAAAGVDVELHVYPGAGH 199
|
|
| Abhydrolase_6 |
pfam12697 |
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ... |
47-200 |
9.48e-10 |
|
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.
Pssm-ID: 463673 [Multi-domain] Cd Length: 211 Bit Score: 57.48 E-value: 9.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 47 IFICHGYGDHSKRYSKFLAqalvdEGFFVLSHDHVGHGKSEGERAQIDSlqkyVRDIFDHIDQIIpkyEGLPIYLFGHSM 126
Cdd:pfam12697 1 VVLVHGAGLSAAPLAALLA-----AGVAVLAPDLPGHGSSSPPPLDLAD----LADLAALLDELG---AARPVVLVGHSL 68
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 156346803 127 GGLIAVLAAQRrpTFFKGVVLSAPALIVDPHKDNkcMRFLGKMVSWVAPSLQLLPAMDPNSMSRDPEQVKAYAE 200
Cdd:pfam12697 69 GGAVALAAAAA--ALVVGVLVAPLAAPPGLLAAL--LALLARLGAALAAPAWLAAESLARGFLDDLPADAEWAA 138
|
|
| COG4188 |
COG4188 |
Predicted dienelactone hydrolase [General function prediction only]; |
40-244 |
1.49e-07 |
|
Predicted dienelactone hydrolase [General function prediction only];
Pssm-ID: 443342 [Multi-domain] Cd Length: 326 Bit Score: 52.03 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 40 SEQPKALIFICHGYGDHSKRYSkFLAQALVDEGFFVLSHDHVGH------GKSEGERAQIDSLQKYVR--DI---FDHID 108
Cdd:COG4188 58 AGGPFPLVVLSHGLGGSREGYA-YLAEHLASHGYVVAAPDHPGSnaadlsAALDGLADALDPEELWERplDLsfvLDQLL 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 109 QIIPKYEGLP-------IYLFGHSMGGLIAVLAAqrrptffkGVVLSAPALIVDPHKDNkcmrflgkmvswvAPSLQLLP 181
Cdd:COG4188 137 ALNKSDPPLAgrldldrIGVIGHSLGGYTALALA--------GARLDFAALRQYCGKNP-------------DLQCRALD 195
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 156346803 182 AMDPNSMSRDPeQVKAYaedplvwhggvkVGIGLAIAHAVDEvqASMESIKWPFLVLHGTADT 244
Cdd:COG4188 196 LPRLAYDLRDP-RIKAV------------VALAPGGSGLFGE--EGLAAITIPVLLVAGSADD 243
|
|
| GrsT |
COG3208 |
Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and ... |
82-149 |
3.87e-06 |
|
Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442441 [Multi-domain] Cd Length: 237 Bit Score: 47.15 E-value: 3.87e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 156346803 82 GHGKSEGERAqIDSLQKYVRDIFDHIDQIIPKyeglPIYLFGHSMGGLIAV-----LAAQRRPTfFKGVVLSA 149
Cdd:COG3208 42 GRGDRLGEPP-LTSLEELADDLAEELAPLLDR----PFALFGHSMGALLAFelarrLERRGRPL-PAHLFVSG 108
|
|
| EstA |
COG1075 |
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ... |
46-138 |
4.46e-06 |
|
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];
Pssm-ID: 440693 [Multi-domain] Cd Length: 106 Bit Score: 44.44 E-value: 4.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 46 LIFIcHGYGDHSKRYSKfLAQALVDEGFFVLSHDhVGHGKSegeraqidSLQKYVRDIFDHIDQIIPKYEGLPIYLFGHS 125
Cdd:COG1075 8 VVLV-HGLGGSAASWAP-LAPRLRAAGYPVYALN-YPSTNG--------SIEDSAEQLAAFVDAVLAATGAEKVDLVGHS 76
|
90
....*....|...
gi 156346803 126 MGGLIAVLAAQRR 138
Cdd:COG1075 77 MGGLVARYYLKRL 89
|
|
| Thioesterase |
pfam00975 |
Thioesterase domain; Peptide synthetases are involved in the non-ribosomal synthesis of ... |
47-137 |
1.39e-05 |
|
Thioesterase domain; Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates. There are also modules within the peptide synthetases that also share this similarity. With respect to antibiotic production, thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic. Thioesterases (non-integrated) have molecular masses of 25-29 kDa.
Pssm-ID: 395776 [Multi-domain] Cd Length: 223 Bit Score: 45.46 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 47 IFICHGYGDHSKRYSKfLAQALVDE-GFFVLSHdhvgHGKSEGERAqIDSLQKYVRDIFDHIDQIIPkyEGlPIYLFGHS 125
Cdd:pfam00975 3 LFCFPPAGGSASSFRS-LARRLPPPaEVLAVQY----PGRGRGEPP-LNSIEALADEYAEALRQIQP--EG-PYALFGHS 73
|
90
....*....|..
gi 156346803 126 MGGLIAVLAAQR 137
Cdd:pfam00975 74 MGGMLAFEVARR 85
|
|
| PRK14875 |
PRK14875 |
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional |
34-151 |
3.23e-05 |
|
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
Pssm-ID: 184875 [Multi-domain] Cd Length: 371 Bit Score: 44.93 E-value: 3.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 34 RTWTSQSEQPKALIFIcHGY-GDHSKRysKFLAQALVdEGFFVLSHDHVGHGKS--EGERAQIDSLQKYVRDIFDHIDqi 110
Cdd:PRK14875 122 RYLRLGEGDGTPVVLI-HGFgGDLNNW--LFNHAALA-AGRPVIALDLPGHGASskAVGAGSLDELAAAVLAFLDALG-- 195
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 156346803 111 IPKyeglpIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPA 151
Cdd:PRK14875 196 IER-----AHLVGHSMGGAVALRLAARAPQRVASLTLIAPA 231
|
|
| YbbA |
COG2819 |
Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; |
121-157 |
4.31e-05 |
|
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
Pssm-ID: 442067 [Multi-domain] Cd Length: 250 Bit Score: 43.82 E-value: 4.31e-05
10 20 30
....*....|....*....|....*....|....*..
gi 156346803 121 LFGHSMGGLIAVLAAQRRPTFFKGVVLSAPALIVDPH 157
Cdd:COG2819 134 LIGHSLGGLFSLYALLKYPDLFGRYIAISPSLWWDDG 170
|
|
| YheT |
COG0429 |
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; |
36-173 |
1.04e-04 |
|
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
Pssm-ID: 440198 [Multi-domain] Cd Length: 323 Bit Score: 43.21 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 36 WTSQSEQPKALIFICHGY-GDHSKRYSKFLAQALVDEGFFVLSHDHVGHGKS-----------EGEraqidslqkyvrDI 103
Cdd:COG0429 53 WSDPPAPSKPLVVLLHGLeGSSDSHYARGLARALYARGWDVVRLNFRGCGGEpnllprlyhsgDTE------------DL 120
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 156346803 104 FDHIDQIIPKYEGLPIYLFGHSMGG--LIAVLAAQRR--PTFFKGVVLSAPaliVDPHkdnKCMRFLGKMVSWV 173
Cdd:COG0429 121 VWVLAHLRARYPYAPLYAVGFSLGGnlLLKYLGEQGDdaPPLKAAVAVSPP---LDLA---ASADRLERGFNRL 188
|
|
| COG2945 |
COG2945 |
Alpha/beta superfamily hydrolase [General function prediction only]; |
43-152 |
1.25e-04 |
|
Alpha/beta superfamily hydrolase [General function prediction only];
Pssm-ID: 442188 [Multi-domain] Cd Length: 201 Bit Score: 42.07 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 43 PKALIFICH---GYGD--HSKRYSKfLAQALVDEGFFVLSHDHVGHGKSEGEraqidslqkyvrdiFDH----------- 106
Cdd:COG2945 22 PRGVALILHphpLFGGtmDNKVVYT-LARALVAAGFAVLRFNFRGVGRSEGE--------------FDEgrgelddaaaa 86
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 156346803 107 IDQIIPKYeGLPIYLFGHSMGGLIAVLAAQRRPTfFKGVVLSAPAL 152
Cdd:COG2945 87 LDWLRAQN-PLPLWLAGFSFGAYVALQLAMRLPE-VEGLILVAPPV 130
|
|
| EntF2 |
COG3319 |
Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase ... |
39-137 |
1.49e-04 |
|
Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442548 [Multi-domain] Cd Length: 855 Bit Score: 43.15 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 39 QSEQPKALIFICHGYGDHSKRYSKfLAQALVDEG-FFVLSHDHVghgksEGERAQIDSLQKYVRDIFDHIDQIIPkyEGl 117
Cdd:COG3319 596 RAGGSGPPLFCVHPAGGNVLCYRP-LARALGPDRpVYGLQAPGL-----DGGEPPPASVEEMAARYVEAIRAVQP--EG- 666
|
90 100
....*....|....*....|
gi 156346803 118 PIYLFGHSMGGLIAVLAAQR 137
Cdd:COG3319 667 PYHLLGWSFGGLVAYEMARQ 686
|
|
| fghA_ester_D |
TIGR02821 |
S-formylglutathione hydrolase; This model describes a protein family from bacteria, yeast, and ... |
121-156 |
1.99e-03 |
|
S-formylglutathione hydrolase; This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well. [Cellular processes, Detoxification]
Pssm-ID: 131868 Cd Length: 275 Bit Score: 38.99 E-value: 1.99e-03
10 20 30
....*....|....*....|....*....|....*.
gi 156346803 121 LFGHSMGGLIAVLAAQRRPTFFKGVvlSAPALIVDP 156
Cdd:TIGR02821 142 ITGHSMGGHGALVIALKNPDRFKSV--SAFAPIVAP 175
|
|
| PLN02824 |
PLN02824 |
hydrolase, alpha/beta fold family protein |
24-152 |
2.75e-03 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 178419 [Multi-domain] Cd Length: 294 Bit Score: 38.57 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 24 KNKDGLSISTRTWTSQSEQPK---------ALIFIcHGYG---DHSKRYSKFLAQAlvdegFFVLSHDHVGHGKS----- 86
Cdd:PLN02824 1 TVKPEPQVETRTWRWKGYNIRyqragtsgpALVLV-HGFGgnaDHWRKNTPVLAKS-----HRVYAIDLLGYGYSdkpnp 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 156346803 87 -EGERAQIDSLQKYVRDIFDHIDQIIpkyeGLPIYLFGHSMGGLIAVLAAQRRPTFFKGVVLSAPAL 152
Cdd:PLN02824 75 rSAPPNSFYTFETWGEQLNDFCSDVV----GDPAFVICNSVGGVVGLQAAVDAPELVRGVMLINISL 137
|
|
| Esterase |
pfam00756 |
Putative esterase; This family contains Esterase D. However it is not clear if all members of ... |
53-156 |
3.19e-03 |
|
Putative esterase; This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.
Pssm-ID: 395613 [Multi-domain] Cd Length: 246 Bit Score: 38.21 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 53 YGDHSKRYSKFlaqalvdegffvlshdHVGHGKSEGERAQ--IDSLQKYVRDIFDHIDQIIPKYEGLpiylFGHSMGGLI 130
Cdd:pfam00756 64 RGGEVSFYSDW----------------DRGLNATEGPGAYayETFLTQELPPLLDANFPTAPDGRAL----AGQSMGGLG 123
|
90 100
....*....|....*....|....*.
gi 156346803 131 AVLAAQRRPTFFKGVvlSAPALIVDP 156
Cdd:pfam00756 124 ALYLALKYPDLFGSV--SSFSPILNP 147
|
|
| Esterase_713_like-2 |
cd12809 |
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
118-146 |
3.72e-03 |
|
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown.
Pssm-ID: 214008 Cd Length: 280 Bit Score: 38.36 E-value: 3.72e-03
10 20
....*....|....*....|....*....
gi 156346803 118 PIYLFGHSMGGLIAVLAAQRRPTFFKGVV 146
Cdd:cd12809 172 PAILITHSQGGPFGWLAADARPDLVKAIV 200
|
|
| LIDHydrolase |
pfam10230 |
Lipid-droplet associated hydrolase; This family of proteins is conserved from plants to humans. ... |
75-183 |
5.55e-03 |
|
Lipid-droplet associated hydrolase; This family of proteins is conserved from plants to humans. The function is as a lipid-droplet hydrolase. Human LDAH plays a role in cholesterol homeostasis.
Pssm-ID: 370901 Cd Length: 261 Bit Score: 37.66 E-value: 5.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156346803 75 VLSHDHVGHGKSEGERAQ----IDSLQKYVRDIFDHIDQIIP--KYEGLPIYLFGHSMGGLIAVLAAQRRPT-FFKGVVL 147
Cdd:pfam10230 35 VLGISHAGHSLEDRNDAKengrVFSLQDQIEHKIDFIRAFLPanSDKDVKLILIGHSIGAYIALEVLKRLSErGIIKCVL 114
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 156346803 148 SAPaLIVDPHKDNKCMR---------FLGKMVSWVAPSLQLLPAM 183
Cdd:pfam10230 115 LFP-TIEDMARSPNGRIltrllcyipFLALVAGFLLRVFKLLPES 158
|
|
| Mbeg1-like |
pfam11187 |
Mbeg1-like; This family includes a group of uncharacterized proteins from bacteria. Recently, ... |
91-135 |
7.57e-03 |
|
Mbeg1-like; This family includes a group of uncharacterized proteins from bacteria. Recently, a member from Gemella sanguinis M325, Mbeg1 (for "microbiome bacteria effector gene") has been identified as the first example of this protein family being associated with a potential effector function in the human microbiome.
Pssm-ID: 402661 [Multi-domain] Cd Length: 224 Bit Score: 36.90 E-value: 7.57e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 156346803 91 AQIDSLqKYVRDIFDHIDQiipkyeglPIYLFGHSMGGLIAVLAA 135
Cdd:pfam11187 67 AQRSAA-KYLNKILQHYPG--------KIYLGGHSKGGNLAIYAA 102
|
|
| |
