NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|116193049|ref|XP_001222337|]
View 

uncharacterized protein CHGG_06242 [Chaetomium globosum CBS 148.51]

Protein Classification

EMC1 family protein( domain architecture ID 10544306)

ER membrane protein complex 1 (EMC1) family protein is a DUF1620 domain-containing protein, most likely a component of the ER membrane protein complex (EMC)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
EMC1_C pfam07774
ER membrane protein complex subunit 1, C-terminal; This is the C-terminal domain of ER ...
2-232 1.98e-115

ER membrane protein complex subunit 1, C-terminal; This is the C-terminal domain of ER membrane protein complex subunit 1. ER membrane protein complex subunit 1 is a component of the ER membrane protein complex (EMC, composed of EMC1, EMC2, EMC3, EMC4, EMC5 and EMC6). In Saccharomyces cerevisiae, the EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).


:

Pssm-ID: 462261  Cd Length: 214  Bit Score: 328.73  E-value: 1.98e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116193049    2 AENWFVCTYFGQyalrdnaaKTIKGYQIFVADLYESDEANDRGPLGDADTFSSIDPiddptggVARPSVVAQSYVLSAPI 81
Cdd:pfam07774   1 SENWIVYSYFND--------EPAKRYEIVVVELYESKEPNDRGSLGSAANFSSLDP-------PPLPHVLSQSYIFPEGI 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116193049   82 SALQVTQTRQGITSRHVLaYLPESHGIVGIPRAIIEPRRPVgRDPTPAEAEEGLFKYHPAIEVDPKSVITHERDVLGVEK 161
Cdd:pfam07774  66 KALAVTQTKQGITSKSLL-VATESGQIVSLPRRLLDPRRPV-RKPTPAEKEEGLIPYDPELPIDPKSVLSHNREVAGVRK 143
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116193049  162 IITAPAIVESTSLVFAYGIDVFGTRVAPSFLFDILGKGFNKVALVGTVLALLAGVLMLAPVVRRKQINLRW 232
Cdd:pfam07774 144 IITSPTLLESTSLVFAYGLDLFCTRVAPSKSFDVLSEDFNKIQLLLTVVALLVGVLVTRPLVRRKQLNAKW 214
 
Name Accession Description Interval E-value
EMC1_C pfam07774
ER membrane protein complex subunit 1, C-terminal; This is the C-terminal domain of ER ...
2-232 1.98e-115

ER membrane protein complex subunit 1, C-terminal; This is the C-terminal domain of ER membrane protein complex subunit 1. ER membrane protein complex subunit 1 is a component of the ER membrane protein complex (EMC, composed of EMC1, EMC2, EMC3, EMC4, EMC5 and EMC6). In Saccharomyces cerevisiae, the EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).


Pssm-ID: 462261  Cd Length: 214  Bit Score: 328.73  E-value: 1.98e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116193049    2 AENWFVCTYFGQyalrdnaaKTIKGYQIFVADLYESDEANDRGPLGDADTFSSIDPiddptggVARPSVVAQSYVLSAPI 81
Cdd:pfam07774   1 SENWIVYSYFND--------EPAKRYEIVVVELYESKEPNDRGSLGSAANFSSLDP-------PPLPHVLSQSYIFPEGI 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116193049   82 SALQVTQTRQGITSRHVLaYLPESHGIVGIPRAIIEPRRPVgRDPTPAEAEEGLFKYHPAIEVDPKSVITHERDVLGVEK 161
Cdd:pfam07774  66 KALAVTQTKQGITSKSLL-VATESGQIVSLPRRLLDPRRPV-RKPTPAEKEEGLIPYDPELPIDPKSVLSHNREVAGVRK 143
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116193049  162 IITAPAIVESTSLVFAYGIDVFGTRVAPSFLFDILGKGFNKVALVGTVLALLAGVLMLAPVVRRKQINLRW 232
Cdd:pfam07774 144 IITSPTLLESTSLVFAYGLDLFCTRVAPSKSFDVLSEDFNKIQLLLTVVALLVGVLVTRPLVRRKQLNAKW 214
 
Name Accession Description Interval E-value
EMC1_C pfam07774
ER membrane protein complex subunit 1, C-terminal; This is the C-terminal domain of ER ...
2-232 1.98e-115

ER membrane protein complex subunit 1, C-terminal; This is the C-terminal domain of ER membrane protein complex subunit 1. ER membrane protein complex subunit 1 is a component of the ER membrane protein complex (EMC, composed of EMC1, EMC2, EMC3, EMC4, EMC5 and EMC6). In Saccharomyces cerevisiae, the EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).


Pssm-ID: 462261  Cd Length: 214  Bit Score: 328.73  E-value: 1.98e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116193049    2 AENWFVCTYFGQyalrdnaaKTIKGYQIFVADLYESDEANDRGPLGDADTFSSIDPiddptggVARPSVVAQSYVLSAPI 81
Cdd:pfam07774   1 SENWIVYSYFND--------EPAKRYEIVVVELYESKEPNDRGSLGSAANFSSLDP-------PPLPHVLSQSYIFPEGI 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116193049   82 SALQVTQTRQGITSRHVLaYLPESHGIVGIPRAIIEPRRPVgRDPTPAEAEEGLFKYHPAIEVDPKSVITHERDVLGVEK 161
Cdd:pfam07774  66 KALAVTQTKQGITSKSLL-VATESGQIVSLPRRLLDPRRPV-RKPTPAEKEEGLIPYDPELPIDPKSVLSHNREVAGVRK 143
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116193049  162 IITAPAIVESTSLVFAYGIDVFGTRVAPSFLFDILGKGFNKVALVGTVLALLAGVLMLAPVVRRKQINLRW 232
Cdd:pfam07774 144 IITSPTLLESTSLVFAYGLDLFCTRVAPSKSFDVLSEDFNKIQLLLTVVALLVGVLVTRPLVRRKQLNAKW 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH