|
Name |
Accession |
Description |
Interval |
E-value |
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
6-881 |
0e+00 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 1660.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 6 NIPKVYDPASVEKKWYKYWEEHRYFHAEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGY 85
Cdd:COG0525 2 ELPKTYDPKEVEAKWYQYWEENGYFKADPDSDKEPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWQPGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 86 DHAGLATQIKVEEVLKkEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVS 165
Cdd:COG0525 82 DHAGIATQAVVERQLA-EEGKSRHDLGREKFLERVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFVR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 166 LYEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGNLWYVRYPVVGEmETYLTIATTRPETMLGDTAVAVNPEDPRYGH 245
Cdd:COG0525 161 LYEKGLIYRGKRLVNWDPKLKTALSDLEVEHEEVKGHLWHIRYPLADG-SGYIVVATTRPETMLGDTAVAVHPEDERYKH 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 246 LVGKMLQLPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERYECRK 325
Cdd:COG0525 240 LIGKTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINILDEDGTINENAGKYRGLDRFEARK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 326 NLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMENIRD 405
Cdd:COG0525 320 AIVADLEELGLLVKVEPHKHSVGHSDRSGTVIEPYLSDQWFVKMKPLAKPAIEAVEDGEIKFVPERWEKTYFHWMENIRD 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 406 WCISRQIWWGHRIPVWYCDAcGEVIASRVDIDKCPKCGG-AVHQDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPTSV 484
Cdd:COG0525 400 WCISRQLWWGHRIPAWYCPD-GEVYVARTEPEACAKAGSvNLTQDEDVLDTWFSSALWPFSTLGWPEKTEDLKYFYPTSV 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 485 LVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGND 564
Cdd:COG0525 479 LVTGFDIIFFWVARMIMMGLHFTGEVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLIDKYGADALRFTLAALASPGRD 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 565 MRFYWERVEATRNFANKIWNASRFALMNMEGYDAEAKQAP--YTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDF 642
Cdd:COG0525 559 IKFDEERVEGYRNFANKLWNASRFVLMNLEGFDPGLDPDPeeLSLADRWILSRLNKTIAEVTEALEKYRFDEAAQALYDF 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 643 IWSEVCDWYIELAKPRLYNkEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLP--HESNSIMIAPWPIVDERL 720
Cdd:COG0525 639 VWNEFCDWYLELAKPRLYG-GDEAAKRETRATLVYVLEQILRLLHPFMPFITEEIWQKLPprKEGESIMLAPWPEADEEL 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 721 FDDKAETGMTAIMESIKAIRNMRAEVNAAPGKKVPAILLV-NAELREIVEANKNYINLMGSIDELIIDDigAGKPENAMA 799
Cdd:COG0525 718 IDEEAEAEFEWLKEVISAIRNIRAEMNIPPSKKLPLLLKGaDEADRARLEENAAYIKRLARLEEITILV--DEKPEGAAS 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 800 AVIAGIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAEELSGKMEAVKERLTY 879
Cdd:COG0525 796 AVVGGAEVFLPLEGLIDVEAERARLEKELAKLEKEIARVEKKLSNEGFVAKAPAEVVEKEREKLAEAEAKLEKLEEQLAR 875
|
..
gi 815697062 880 LA 881
Cdd:COG0525 876 LK 877
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
6-881 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 1580.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 6 NIPKVYDPASVEKKWYKYWEEHRYFHAEvEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGY 85
Cdd:PRK05729 4 ELPKTYDPKEVEAKWYQKWEEKGYFKPD-DNSKKPFSIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWLPGT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 86 DHAGLATQIKVEEVLKKEeGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVS 165
Cdd:PRK05729 83 DHAGIATQMVVERQLAAE-GKSRHDLGREKFLEKVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFVR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 166 LYEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGNLWYVRYPVVGEmETYLTIATTRPETMLGDTAVAVNPEDPRYGH 245
Cdd:PRK05729 162 LYEKGLIYRGKRLVNWDPKLQTALSDLEVEYKEVKGKLWHIRYPLADG-SDYLVVATTRPETMLGDTAVAVNPEDERYKH 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 246 LVGKMLQLPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERYECRK 325
Cdd:PRK05729 241 LIGKTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINIMDEDGTINENPGEYQGLDRFEARK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 326 NLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMENIRD 405
Cdd:PRK05729 321 AIVADLEELGLLVKIEPHTHSVGHSDRSGVVIEPYLSDQWFVKMKPLAKPALEAVENGEIKFVPERWEKTYFHWMENIQD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 406 WCISRQIWWGHRIPVWYCDAcGEVIASRVDIDKCPKCggAVHQDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPTSVL 485
Cdd:PRK05729 401 WCISRQLWWGHRIPAWYDED-GEVYVGREEPEAREKA--LLTQDEDVLDTWFSSALWPFSTLGWPEKTEDLKRFYPTSVL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 486 VTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDM 565
Cdd:PRK05729 478 VTGFDIIFFWVARMIMMGLHFTGQVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLIDKYGADALRFTLAALASPGRDI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 566 RFYWERVEATRNFANKIWNASRFALMNMEGYDAEAKQAP--YTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFI 643
Cdd:PRK05729 558 RFDEERVEGYRNFANKLWNASRFVLMNLEGADVGELPDPeeLSLADRWILSRLNRTVAEVTEALDKYRFDEAARALYEFI 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 644 WSEVCDWYIELAKPRLYNkedpEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPHESN--SIMIAPWPIVDERLf 721
Cdd:PRK05729 638 WNEFCDWYLELAKPVLQE----AAKRATRATLAYVLEQILRLLHPFMPFITEELWQKLAPLGIeeSIMLAPWPEADEAI- 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 722 DDKAETGMTAIMESIKAIRNMRAEVNAAPGKKVPAILL-VNAELREIVEANKNYINLMGSIDELIIDDIGAGKPENAMAA 800
Cdd:PRK05729 713 DEAAEAEFEWLKELITAIRNIRAEMNIPPSKKLPLLLKgADAEDRARLEANEAYIKRLARLESLEILADDEEAPEGAASA 792
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 801 VIAGIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAEELSGKMEAVKERLTYL 880
Cdd:PRK05729 793 VVGGAELFLPLEGLIDVEAELARLEKELAKLEKEIERVEKKLSNEGFVAKAPEEVVEKEREKLAEYEEKLAKLKERLARL 872
|
.
gi 815697062 881 A 881
Cdd:PRK05729 873 K 873
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
7-864 |
0e+00 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 1215.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 7 IPKVYDPASVEKKWYKYWEEHRYFHAEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYD 86
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPDGNSNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 87 HAGLATQIKVEEVLKKEeGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSL 166
Cdd:TIGR00422 81 HAGIATQVKVEKKLGAE-GKTKHDLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 167 YEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGNLWYVRYPVVGEMETYLTIATTRPETMLGDTAVAVNPEDPRYGHL 246
Cdd:TIGR00422 160 YEKGLIYRGEYLVNWDPKLNTAISDIEVEYKEVKGKLYYIRYPLANGSKDYLVVATTRPETMFGDTAVAVHPEDERYKHL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 247 VGKMLQLPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERYECRKN 326
Cdd:TIGR00422 240 IGKKVILPLTGRKIPIIADEYVDMEFGTGAVKVTPAHDFNDYEWGKRHNLEFINILDEDGLLNENAGKYQGLTRFEARKK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 327 LVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMENIRDW 406
Cdd:TIGR00422 320 IVEDLKEEGLLVKIEPHTHNVGTCWRSGTVVEPLLSKQWFVKVEKLADKALEAAEEGEIKFVPKRMEKRYLNWLRNIKDW 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 407 CISRQIWWGHRIPVWYCDACGEVIASRVD--IDKCPKCGGAVH--QDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPT 482
Cdd:TIGR00422 400 CISRQLIWGHRIPVWYCKECGEVYVAKEEplPDDKTNTGPSVEleQDTDVLDTWFSSSLWPFSTLGWPDETKDLKKFYPT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 483 SVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPG 562
Cdd:TIGR00422 480 DLLVTGYDIIFFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 563 NDMRFYWERVEATRNFANKIWNASRFALMNMEGYDAEAK-QAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYD 641
Cdd:TIGR00422 560 DDINFDWKRVESARNFLNKLWNASRFVLMNLSDDLELSGgEEKLSLADRWILSKLNRTIKEVRKALDKYRFAEAAKALYE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 642 FIWSEVCDWYIELAKPRLYNkEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPHESNSIMIAPWPIVDERLF 721
Cdd:TIGR00422 640 FIWNDFCDWYIELVKYRLYN-GNEAEKKAARDTLYYVLDKALRLLHPFMPFITEEIWQHFKEGADSIMLQSYPVVDAEFV 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 722 DDKAETGMTAIMESIKAIRNMRAEVNAAPGKKVPAIL-LVNAELREIVEANKNYINLMGSIDELiidDIGAGKPE--NAM 798
Cdd:TIGR00422 719 DEEAEKAFELLKEIIVSIRNLKAESNIPPNAPLKVLLiYTEAETAERLKLNAVDIKGAINFSEV---EVVIEKPEvtEAV 795
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 815697062 799 AAVIAGIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAE 864
Cdd:TIGR00422 796 VELVPGFEIIIPVKGLINKAKELARLQKQLDKEKKEVIRIEGKLENEGFVKKAPKEVIEKEKEKLE 861
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
7-878 |
0e+00 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 1130.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 7 IPKVYDPASVEKKWYKYWEEHRYFHA-EVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGY 85
Cdd:PRK14900 15 LAKGYEHREVEARWYPFWQERGYFHGdEHDRTRPPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPGT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 86 DHAGLATQIKVEEVLKKEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVS 165
Cdd:PRK14900 95 DHAGIATQMIVEKELKKTEKKSRHDLGREAFLERVWAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFVR 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 166 LYEKGLIYQGSRITNWCVNCNTALSDIEVEHEDD-AGNLWYVRYPVVGEMETyLTIATTRPETMLGDTAVAVNPEDPRYG 244
Cdd:PRK14900 175 LHEEGLIYREKKLINWCPDCRTALSDLEVEHEEAhQGELWSFAYPLADGSGE-IVVATTRPETMLGDTAVAVHPLDPRYM 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 245 HLVGKMLQLPLTERQIPIIADS-YVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERYEC 323
Cdd:PRK14900 254 ALHGKKVRHPITGRTFPIVADAiLVDPKFGTGAVKVTPAHDFNDFEVGKRHGLEMITVIGPDGRMTAEAGPLAGLDRFEA 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 324 RKNLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMENI 403
Cdd:PRK14900 334 RKEVKRLLAEQGLDRGAKPHVLPLGRCQRSATILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIPEQWTNTYMAWMRNI 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 404 RDWCISRQIWWGHRIPVWYCDAcGEVIASRVDIDKCPKCGGA-VHQDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPT 482
Cdd:PRK14900 414 HDWCISRQLWWGHQIPAWYCPD-GHVTVARETPEACSTCGKAeLRQDEDVLDTWFSSGLWPFSTMGWPEQTDTLRTFYPT 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 483 SVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPG 562
Cdd:PRK14900 493 SVMETGHDIIFFWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSKTKGNVIDPLVITEQYGADALRFTLAALTAQG 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 563 NDMRFYWERVEATRNFANKIWNASRFALMNMEGYDAEA---KQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLI 639
Cdd:PRK14900 573 RDIKLAKERIEGYRAFANKLWNASRFALMNLSGYQERGedpARLARTPADRWILARLQRAVNETVEALEAFRFNDAANAV 652
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 640 YDFIWSEVCDWYIELAKPRLYNkEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPHE------SNSIMIAPW 713
Cdd:PRK14900 653 YAFVWHELCDWYIELAKEALAS-EDPEARRSVQAVLVHCLQTSYRLLHPFMPFITEELWHVLRAQvgasawADSVLAAEY 731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 714 PIVDErlFDDKAETGMTAIMESIKAIRNMRAEVNAAPGKKVPA-----ILLVNAELREIVEAN-KNYINLMGSIDELIID 787
Cdd:PRK14900 732 PRKGE--ADEAAEAAFRPVLGIIDAVRNIRGEMGIPWKVKLGAqapveIAVADPALRDLLQAGeLARVHRVAGVEGSRLV 809
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 788 DIGAG-KPENAMAAVIAGIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAEEL 866
Cdd:PRK14900 810 VAAATaPAPQSAVGVGPGFEVRVPLAGVIDLAAETARVDKEIGKVDQDLAVLERKLQNPSFVQNAPPAVVEKDRARAEEL 889
|
890
....*....|....*
gi 815697062 867 ---SGKMEAVKERLT 878
Cdd:PRK14900 890 rekRGKLEAHRAMLS 904
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
4-867 |
0e+00 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 996.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 4 EHNIPKVYDPASVEKKWYKYWEEHRYFH----AEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNT 79
Cdd:PTZ00419 21 ISSMAASYDPKEVESGWYEWWEKSGFFKpaedAKSLNSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDET 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 80 LWMPGYDHAGLATQIKVEEVLKKEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAV 159
Cdd:PTZ00419 101 LWVPGTDHAGIATQVVVEKKLMKEENKTRHDLGREEFLKKVWEWKDKHGNNICNQLRRLGSSLDWSREVFTMDEQRSKAV 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 160 REVFVSLYEKGLIYQGSRITNWCVNCNTALSDIEVEHED----------------DAGNLWYVRYPVVGEMETYLTIATT 223
Cdd:PTZ00419 181 KEAFVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEiekptkitipgydkkvEVGVLWHFAYPLEDSGQEEIVVATT 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 224 RPETMLGDTAVAVNPEDPRYGHLVGKMLQLPLT-ERQIPIIADS-YVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVV 301
Cdd:PTZ00419 261 RIETMLGDVAVAVHPKDERYKKLHGKELIHPFIpDRKIPIIADDeLVDMEFGTGAVKITPAHDPNDYEIAKRHNLPFINI 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 302 IGMDGYMTEEAGKFAGQERYECRKNLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVE 381
Cdd:PTZ00419 341 FTLDGKINENGGEFAGMHRFDCRRKIEEELKEMGLLRDKVPNPMRLPRCSRSGDIVEPMLIPQWYVNCKDMAKRAVEAVR 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 382 DGRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWYCDACGEVIASRV--------DIDKC----------PKCG 443
Cdd:PTZ00419 421 NGELKIIPSSHENVWYHWLENIQDWCISRQLWWGHRIPAYRVISKGPETDPSDeepwvvarSEEEAlekakkkfglSEED 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 444 GAVHQDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRD 523
Cdd:PTZ00419 501 FELEQDEDVLDTWFSSGLFPFSTLGWPDQTDDLQRFFPTSLLETGSDILFFWVARMVMMSLHLTDKLPFKTVFLHAMVRD 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 524 SQGRKMSKSLGNGIDPLEVIE-------------------------------------KYGADTLRFMLITGNTPGNDMR 566
Cdd:PTZ00419 581 SQGEKMSKSKGNVIDPLEVIEgislqdlnqklyegnlpekeikraielqkkefpngipECGTDALRFGLLAYTQQGRNIN 660
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 567 FYWERVEATRNFANKIWNASRFALMNMEG--------YDAEAKQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRL 638
Cdd:PTZ00419 661 LDINRVVGYRHFCNKLWNAVKFALMKLLKdfnlpnstLFKPNNVESLPWEDKWILHRLNVAIKEVTEGFKEYDFSEATQA 740
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 639 IYDFIWSEVCDWYIELAKPRLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLP---HESNSIMIAPWPI 715
Cdd:PTZ00419 741 TYNFWLYELCDVYLELIKPRLSKQSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEELYQRLPnylRKSESISIAKYPQ 820
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 716 VDERLFDDKAETGMTAIMESIKAIRNMRAEVNAAPGKKvPAILLV--NAELREIVEANKNYINLMGSIDEL-IIDDIGAG 792
Cdd:PTZ00419 821 PNPGWNNEALDEEMKIIMSIVKSIRSLIATLGIPNKTK-PDCYVTakDAELIELIESAENLISTLAKIGSVsVIPPIEEE 899
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 815697062 793 KPENA---MAAVIAGIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAEELS 867
Cdd:PTZ00419 900 AEVPKgcgFDVVDNKVIIYLNLDEFIDLKKELAKLEKKLAKLQKSLESYLKKISIPNYEDKVPEDVRKLNDEKIDELN 977
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
7-880 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 927.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 7 IPKVYDPASvEKKWYKYWEEHRYFHAEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYD 86
Cdd:PLN02943 57 TAKSFDFTS-EERIYNWWESQGYFKPNFDRGGDPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTD 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 87 HAGLATQIKVEEVLKKEeGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSL 166
Cdd:PLN02943 136 HAGIATQLVVEKMLASE-GIKRTDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRL 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 167 YEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGNLWYVRYPVVGEMETYLTIATTRPETMLGDTAVAVNPEDPRYGHL 246
Cdd:PLN02943 215 HEKGLIYQGSYMVNWSPNLQTAVSDLEVEYSEEPGTLYYIKYRVAGGSEDFLTIATTRPETLFGDVAIAVNPEDDRYSKY 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 247 VGKMLQLPLT-ERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFagqeRYECRK 325
Cdd:PLN02943 295 IGKMAIVPMTyGRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARKLGLPILNVMNKDGTLNEVAGLY----WFEARE 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 326 NLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMENIRD 405
Cdd:PLN02943 371 KLWSDLEETGLAVKKEPHTLRVPRSQRGGEVIEPLVSKQWFVTMEPLAEKALKAVENGELTIIPERFEKIYNHWLSNIKD 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 406 WCISRQIWWGHRIPVWYC---DACGEVIASRVDIDKCPKC----GGAV--HQDEDALDTWFSSALWPFSTMGWPE-KTDL 475
Cdd:PLN02943 451 WCISRQLWWGHRIPVWYIvgkDCEEDYIVARSAEEALEKArekyGKDVeiYQDPDVLDTWFSSALWPFSTLGWPDvSAED 530
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 476 LKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFML 555
Cdd:PLN02943 531 FKKFYPTTVLETGHDILFFWVARMVMMGIEFTGTVPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTIKEFGTDALRFTL 610
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 556 ITGnTPGNDMRFYWERVEATRNFANKIWNASRFALMNMEG--------------YDAEAKQAPYTLADQWILSRLQHTVK 621
Cdd:PLN02943 611 ALG-TAGQDLNLSTERLTSNKAFTNKLWNAGKFVLQNLPSqsdtsawehilackFDKEESLLSLPLPECWVVSKLHELID 689
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 622 DVTELLGRFELGEAGRLIYDFIWSEVCDWYIELAKPRLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL 701
Cdd:PLN02943 690 SVTTSYDKYFFGDVGREIYDFFWSDFADWYIEASKTRLYHSGDNSALSRAQAVLLYVFENILKLLHPFMPFVTEELWQAL 769
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 702 PHESNSIMIAPWPivderlfddkaETGMTAIMESIK----------AIRNMRAEVNAAPGKKVPAILLVNAELREIVEAN 771
Cdd:PLN02943 770 PYRKEALIVSPWP-----------QTSLPKDLKSIKrfenlqsltrAIRNARAEYSVEPAKRISASIVASAEVIEYISKE 838
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 772 KNYINLMGSID--ELIIDDIGAGKPENAMAAVIA-GIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFL 848
Cdd:PLN02943 839 KEVLALLSRLDlqNVHFTDSPPGDANQSVHLVASeGLEAYLPLADMVDISAEVERLSKRLSKMQTEYDALAARLSSPKFV 918
|
890 900 910
....*....|....*....|....*....|..
gi 815697062 849 AKAPADVVEKEKAKAEELSGKMEAVKERLTYL 880
Cdd:PLN02943 919 EKAPEDVVRGVREKAAEAEEKIKLTKNRLAFL 950
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
7-875 |
0e+00 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 785.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 7 IPKVYDPASVEKKWYKYWEEHRYFHAEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYD 86
Cdd:PLN02381 96 MAKQYSPSAVEKSWYAWWEKSGYFGADAKSSKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPGVD 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 87 HAGLATQIKVEEVLKKEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSL 166
Cdd:PLN02381 176 HAGIATQVVVEKKLMRERHLTRHDIGREEFVSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRL 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 167 YEKGLIYQGSRITNWCVNCNTALSDIEVEHED----------------DAGNLWYVRYPVVGEMETyLTIATTRPETMLG 230
Cdd:PLN02381 256 YKEGLIYRDIRLVNWDCTLRTAISDVEVDYIDikertllkvpgydkpvEFGVLTSFAYPLEGGLGE-IVVATTRIETMLG 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 231 DTAVAVNPEDPRYGHLVGKMLQLPLTERQIPIIADS-YVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMT 309
Cdd:PLN02381 335 DTAIAIHPDDERYKHLHGKFAVHPFNGRKLPIICDAiLVDPNFGTGAVKITPAHDPNDFEVGKRHNLEFINIFTDDGKIN 414
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 310 EEAG-KFAGQERYECRKNLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDGRT--- 385
Cdd:PLN02381 415 SNGGsEFAGMPRFAAREAVIEALQKKGLYRGAKNNEMRLGLCSRTNDVVEPMIKPQWFVNCSSMAKQALDAAIDGENkkl 494
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 386 QFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWYC----DACGEV-------IASRVDID-------KCPKCGGAVH 447
Cdd:PLN02381 495 EFIPKQYLAEWKRWLENIRDWCISRQLWWGHRIPAWYVtledDQLKELgsyndhwVVARNESDalleasqKFPGKKFELS 574
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 448 QDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGR 527
Cdd:PLN02381 575 QDPDVLDTWFSSGLFPLSVLGWPDDTDDLKAFYPTSVLETGHDILFFWVARMVMMGMQLGGDVPFRKVYLHPMIRDAHGR 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 528 KMSKSLGNGIDPLEVIE-------------------------------------KYGADTLRFMLITGNTPGNDMRFYWE 570
Cdd:PLN02381 655 KMSKSLGNVIDPLEVINgisleglhkrleegnldpkelvvakegqkkdfpngiaECGTDALRFALVSYTAQSDKINLDIL 734
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 571 RVEATRNFANKIWNASRFALMNME-GYDAEAKQAPYTLAD--QWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWSEV 647
Cdd:PLN02381 735 RVVGYRQWCNKLWNAVRFAMSKLGdDYTPPATLSVETMPFscKWILSVLNKAISKTVSSLDAYEFSDAASTVYSWWQYQF 814
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 648 CDWYIELAKPRLYNkEDPE---ARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPH-----ESNSIMIAPWPIVDER 719
Cdd:PLN02381 815 CDVFIEAIKPYFAG-DNPEfasERAAAQDTLWICLDTGLRLLHPFMPFVTEELWQRLPQpkdhtRKDSIMISEYPSAVEA 893
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 720 LFDDKAETGMTAIMESIKAIRNMRAEVNAA-PGKKVPAILLV-NAELREIVEANKNYINLMGSID--ELIIDDIGAGKPE 795
Cdd:PLN02381 894 WTNEKVEYEMDLVLSTVKCLRSLRAEVLEKqKNERLPAFALCrNQEIAAIIKSHQLEILTLANLSslKVLLSENDAPPAG 973
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 796 NAMAAVIAGIEVYLPLAGLIDVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAEELSGKMEAVKE 875
Cdd:PLN02381 974 CAFENVNENLKVYLQAQGAVNAEAELEKLRNKMDEIQKQQEKLEKKMNASGYKEKVPANIQEEDARKLTKLLQELEFFEK 1053
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
19-567 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 721.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 19 KWYKYWEEHRYFHAEVEADK--KPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKV 96
Cdd:pfam00133 1 QIYEFWDEQGYFKPELEKRKgkPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 97 EEVLKKEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKGLIYQGS 176
Cdd:pfam00133 81 EKKLGIKEKKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 177 RITNWCVNCNTALSDIEVEHEDDAGNLWYVRYPVVGEMETYLTIATTRPETMLGDTAVAVNPE----------------- 239
Cdd:pfam00133 161 KLVNWSPALNTALSNLEVEYKDVKGPSIHVAFPLADDEGASLVIWTTTPWTLPGNTAVAVNPEfdyvitgegyilaeall 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 240 --------------DPRYGHLVGKMLQLPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMD 305
Cdd:pfam00133 241 kslykkgtdkkileDFRGKELEGKEAIHPFVNREIPIITDDYVDMEFGTGAVHIAPAHGENDYEVGQRHNLEVINPVDDD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 306 GYMTEEAGKFAGQERYECRKNLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEDgrT 385
Cdd:pfam00133 321 GTFTEEAPDFQGVYRFDARKKIVELLTEKGLLLKIEPFTHSYPFCWRSGTPIIPRATPQWFVRMDELADQALEAVEK--V 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 386 QFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWYCDACGEVI---------------------ASRVDIDKCPKCGG 444
Cdd:pfam00133 399 QFVPKSGEKRYFNWLANIQDWCISRQRWWGHPIPAWVSKDTEEVVcrgelfelvagrfeeegsikwLHREAKDKLGYGKG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 445 AVHQDEDALDTWFSSALWPFSTMGWPEK-TDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRD 523
Cdd:pfam00133 479 TLEQDEDVLDTWFSSGSWPFSTLGWPFVnTEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSVPFKNVLVHGLVRD 558
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 815697062 524 SQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLItGNTPGNDMRF 567
Cdd:pfam00133 559 EQGRKMSKSLGNVIDPLDVIDKYGADALRLWLA-NSDYGRDINL 601
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
2-801 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 684.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 2 AEEHNIPKVYDPASVEKKWYKYWEEHRYFHAEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLW 81
Cdd:PRK13208 1 KMMPELPKKYDPEELEEKWQKIWEEEGTYKFDPDERKPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 82 MPGYDHAGLATQIKVEevlkKEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVRE 161
Cdd:PRK13208 81 PQGWDDNGLPTERKVE----KYYGIRKDDISREEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTISPEYRRISQK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 162 VFVSLYEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGNLWYVRYPVvgEMETYLTIATTRPETMLGDTAVAVNPEDP 241
Cdd:PRK13208 157 SFLDLYKKGLIYRAEAPVLWCPRCETAIAQAEVEYREREGKLNYIKFPV--EDGEEIEIATTRPELLPACVAVVVHPDDE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 242 RYGHLVGKMLQLPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERY 321
Cdd:PRK13208 235 RYKHLVGKTAIVPLFGVEVPILADPLVDPDFGTGAVMICTFGDKTDVTWWRELNLPTRIIIDEDGRMTEAAGKLAGLTIE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 322 ECRKNLVHELQEKGYLVKIEEHNHAVGHCQRCRSVIEPLVSKQWFVKMEPLvKAAVdcVEDGRT-QFVPERFTKTYTGWM 400
Cdd:PRK13208 315 EARKKIVEDLKSGGLLGKQEPIKHNVKFCERCDTPLEILVTRQWFIKVLDL-KEEL--LERGKEiNWYPEHMRVRLENWI 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 401 ENIR-DWCISRQIWWGHRIPVWYCDACGEVI-ASR----VD-------IDKCPKCG-GAVHQDEDALDTWFSSALWPFST 466
Cdd:PRK13208 392 EGLNwDWCISRQRYFGTPIPVWYCKDCGHPIlPDEedlpVDptkdeppGYKCPQCGsPGFEGETDVMDTWATSSITPLIV 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 467 MGWPEKTDLLKQFYPTSVLVTGYDIIFFW----VAR-MLIMGmefmkDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLE 541
Cdd:PRK13208 472 TGWERDEDLFEKVFPMDLRPQGHDIIRTWlfytILRaYLLTG-----KLPWKNIMISGMVLDPDGKKMSKSKGNVVTPEE 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 542 VIEKYGADTLRFMLITGnTPGNDMRFYWERVEATRNFANKIWNASRFALMnMEGYDAEAKQAPYTLADQWILSRLQHTVK 621
Cdd:PRK13208 547 LLEKYGADAVRYWAASA-RLGSDTPFDEKQVKIGRRLLTKLWNASRFVLH-FSADPEPDKAEVLEPLDRWILAKLAKVVE 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 622 DVTELLGRFELGEAGRLIYDFIWSEVCDWYIELAKPRLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL 701
Cdd:PRK13208 625 KATEALENYDFAKALEEIESFFWHVFCDDYLELVKSRAYGEDEEEEQKSARYTLYTVLDTLLRLLAPFLPFITEEVWSWL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 702 phESNSIMIAPWPIVDERLFDDKAETGMTAIMESIKAIRNMRAEVNAAPGKKVPAILLVNAELREIVEANKNYINLMGSI 781
Cdd:PRK13208 705 --YGGSVHRASWPEPDEELIDEEDEELGELAKEILSAVRKYKSEAGLSLNAPLKKVEVYGPADLELLEAAEEDLKAAGNI 782
|
810 820
....*....|....*....|
gi 815697062 782 DELiidDIGAGKPENAMAAV 801
Cdd:PRK13208 783 EEL---ELVEGDPELEVEII 799
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
39-567 |
0e+00 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 579.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 39 KPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKVEEVLKKEeGKTRYDLGREEFIK 118
Cdd:cd00817 1 PVFVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGIE-GKTRHDLGREEFLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 119 RVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKGLIYQGSRITNWCVNCNTALSDIEVehed 198
Cdd:cd00817 80 KCWEWKEESGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 199 dagnlwyvrypvvgemetyltiattrpetmlgdtavavnpedpryghlvgkmlqlplterqipiiadsyvdlefgtgavk 278
Cdd:cd00817 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 279 itpahdpndfemgmrhnlesivvigmdgymteeagkfagqeryecrknlvhelqekgylvkieehnhavghCQRCRSVIE 358
Cdd:cd00817 156 -----------------------------------------------------------------------CSRSGDVIE 164
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 359 PLVSKQWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWYCDACGEVIASRVDID- 437
Cdd:cd00817 165 PLLKPQWFVKVKDLAKKALEAVKEGDIKFVPERMEKRYENWLENIRDWCISRQLWWGHRIPAWYCKDGGHWVVAREEDEa 244
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 438 -------KCPKCGGA-VHQDEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKD 509
Cdd:cd00817 245 idkaapeACVPCGGEeLKQDEDVLDTWFSSSLWPFSTLGWPEETKDLKKFYPTSLLVTGHDIIFFWVARMIMRGLKLTGK 324
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 815697062 510 IPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRF 567
Cdd:cd00817 325 LPFKEVYLHGLVRDEDGRKMSKSLGNVIDPLDVIDGYGADALRFTLASAATQGRDINL 382
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
8-807 |
7.77e-170 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 517.33 E-value: 7.77e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 8 PKVYDPASVEKKWYKYWEEHRYFHAEVE--ADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGY 85
Cdd:COG0060 13 PMRANLPKREPEILKFWEENDIYEKSREarAGRPKFVLHDGPPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGW 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 86 D-HaGLATQIKVEEVLKKEeGKTRYDLGREEFIKR----VWEWKDKYgdriIEQLKSLGVSCDWERKRFTMDEGCSQAVR 160
Cdd:COG0060 93 DcH-GLPIELKVEKELGIK-KKDIEKVGIAEFREKcreyALKYVDEQ----REDFKRLGVWGDWDNPYLTMDPEYEESIW 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 161 EVFVSLYEKGLIYQGSRITNWCVNCNTALSDIEVE---HEDDAgnlWYVRYPVVGEME------TYLTIATTRPETMLGD 231
Cdd:COG0060 167 WALKKLYEKGLLYKGLKPVPWCPRCGTALAEAEVEykdVTSPS---IYVKFPVKDEKAlllledAYLVIWTTTPWTLPAN 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 232 TAVAVNPE---------DP---------------RYGH-------------LVGKMLQLPL-----TERQIPIIADSYVD 269
Cdd:COG0060 244 LAVAVHPDidyvlvevtGGerlilaealveavlkELGIedyevlatfkgaeLEGLRYEHPFyyvvgYDRAHPVILGDYVT 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 270 LEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERYECRKNLVHELQEKGYLVKIEEHNHAVGH 349
Cdd:COG0060 324 TEDGTGIVHTAPGHGEDDFEVGKKYGLPVLNPVDDDGRFTEEAPLFAGLFVKDANPAIIEDLKERGALLAREKITHSYPH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 350 CQRCRSviePLV---SKQWFVKMEPLVKAAVDCVEDgrTQFVPE----RFTKtytgWMENIRDWCISRQIWWGHRIPVWY 422
Cdd:COG0060 404 CWRCKT---PLIyraTPQWFISMDKLRDRALEAIEK--VNWIPEwgegRFGN----MLENRPDWCISRQRYWGVPIPIWV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 423 CDACGE------VIASRVD-------------------ID---KCPKCGGAVHQDEDALDTWFSSALWPFSTM------G 468
Cdd:COG0060 475 CEDCGElhrteeVIGSVAElleeegadawfeldlhrpfLDetlKCPKCGGTMRRVPDVLDVWFDSGSMHFAVLenreelH 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 469 WP-----EKTDllkQ----FYptSVLVTGydiiffwvarMLIMGmefmkDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDP 539
Cdd:COG0060 555 FPadfylEGSD---QtrgwFY--SSLLTS----------TALFG-----RAPYKNVLTHGFVLDEDGRKMSKSLGNVVDP 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 540 LEVIEKYGADTLRFMLITgNTPGNDMRFYWERVEATRNFANKIWNASRFALMNMEGYDAEAKQAPY---TLADQWILSRL 616
Cdd:COG0060 615 QEVIDKYGADILRLWVAS-SDYWGDLRFSDEILKEVRDVYRRLRNTYRFLLANLDDFDPAEDAVPYedlPELDRWILSRL 693
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 617 QHTVKDVTELLGRFELGEAGRLIYDFIWSEVCDWYIELAKPRLYN-KEDPEARATAQHVLAEVLTSAMKLLHPYMPFITE 695
Cdd:COG0060 694 NELIKEVTEAYDNYDFHRAYRALHNFCVEDLSNWYLDISKDRLYTeAADSLDRRAAQTTLYEVLETLVRLLAPILPFTAE 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 696 EIYQCLPHESN-SIMIAPWPIVDERLFDDKAETGMTAIMESI----KAIRNMRAE------VNAAPgkkvpaILLVNAEL 764
Cdd:COG0060 774 EIWQNLPGEAEeSVHLADWPEVDEELIDEELEAKWDLVREVRsavlKALEAARKEklirqpLEAAV------VLYADEEL 847
|
890 900 910 920
....*....|....*....|....*....|....*....|....*....
gi 815697062 765 REIVEANKNYINlmgsiDELIIDDI-----GAGKPENAMAAV-IAGIEV 807
Cdd:COG0060 848 AAALESLGDLLA-----EELNVSEVelvddAEDLGKDALKALdVEGISV 891
|
|
| ileS |
TIGR00392 |
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ... |
8-749 |
6.31e-159 |
|
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ligase and is particularly closely related to the valyl tRNA synthetase. This model may recognize IleS from every species, including eukaryotic cytosolic and mitochondrial forms. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273054 [Multi-domain] Cd Length: 861 Bit Score: 486.88 E-value: 6.31e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 8 PKVYDPASVEKKWYKYWEEHRYFH--AEVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGY 85
Cdd:TIGR00392 3 PMRGNLSKREEKILAFWQENDIFEkvKKLNKGKPEFIFHDGPPYANGSIHLGHALNKILKDIILRYKTMQGFNVTRKPGW 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 86 DHAGLATQIKVEEVLKKEEGKTRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVS 165
Cdd:TIGR00392 83 DTHGLPIEHKVEKKLGISGKKEISSLEIEEFREKCREFALKQIEEQREQFQRLGVWGDWENPYKTMDPSYEESQWWLFKE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 166 LYEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGNLW----YVRYPVVGEMETY-------LTIATTRPETMLGDTAV 234
Cdd:TIGR00392 163 AHEKGLLYRGLKPVYWSPRCRTALAEAEVEYKENYKDVKdpsiYVKFPVKKDKKTYlkvklssLLIWTTTPWTLPSNLAI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 235 AVNPE----------DPRYgHLVGKML---------------------QLPLTERQIP--------------IIADSYVD 269
Cdd:TIGR00392 243 AVHPDfeyalvqdntKVEY-FILAKKLveklynkagsdyeiiktfkgsDLEGLEYEHPlydfvsqlkegapvVIGGDHVT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 270 LEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAG-------KFAGQERYECRKNLVHELQEKGYLVKIEE 342
Cdd:TIGR00392 322 TEDGTGIVHTAPGHGEEDYEIGKKYGLEVLSPVDEKGVYTEGVNdfqgrfvKDADKDIIKANKIIIEQLKDKGLLLKAEK 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 343 HNHAVGHCQRCRSVIEPLVSKQWFVKMEPLVKAAVDCVEdgRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWY 422
Cdd:TIGR00392 402 ITHSYPHCWRTKTPVIYRATEQWFIKTKDIKDQMLEQIK--KVNWVPEWGEGRFGNWLENRPDWCISRQRYWGIPIPIWY 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 423 CDACGEVIAS---------------RVDIDK-----------CPKCGGAVHQDEDALDTWFSSALWPFSTMGWPEKTDLL 476
Cdd:TIGR00392 480 CEDTGEPIVVgsieelielielkgiDAWFEDlhrdfldkitlKSGDGGEYRRVPDVLDVWFDSGSMPYASIHYPFENEKF 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 477 KQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLI 556
Cdd:TIGR00392 560 KEVFPADFILEGSDQTRGWFYSSLAIGTALFGQAPYKNVITHGFTLDEKGRKMSKSLGNVVDPLKVINKYGADILRLYVA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 557 TgNTPGNDMRFYWERV-EATRNFANKIWNASRFAL--MNMEGYDAEAKQAPY---TLADQWILSRLQHTVKDVTELLGRF 630
Cdd:TIGR00392 640 S-SDPWEDLRFSDEILkQVVEKYRKIRWNTYRFLLtyANLDKFDPLFNSVAVekfPEEDRWILSRLNSLVEEVNEALEKY 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 631 ELGEAGRLIYDFIWSEVCDWYIELAKPRLY-NKEDPEARAtAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPHESN--S 707
Cdd:TIGR00392 719 NFHKVLRALQDFIVEELSNWYIRIIRDRLYcEAKDNDKRA-AQTTLYYALLTLVRLLAPFLPHTAEEIYQNLPGGEEeeS 797
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 815697062 708 IMIAPWPIVDERLFDDKAETGMTAIMESIKAIRNMRAEVNAA 749
Cdd:TIGR00392 798 VHLNLWPEVDEEFIDEALEANMAIVREIVEAFLALRDAANKK 839
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
22-749 |
4.59e-83 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 287.44 E-value: 4.59e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 22 KYWEEHRYFHAEVE-ADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKVEEVL 100
Cdd:PLN02843 14 KLWEENQVYKRVSDrNNGESFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLPIELKVLQSL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 101 KKEEgktRYDLGREEFIKRVWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKGLIYQGSRITN 180
Cdd:PLN02843 94 DQEA---RKELTPIKLRAKAAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGRKPVH 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 181 WCVNCNTALSDIEVEH-EDDAGNLWYVRYPVVGEMET------------YLTIATTRPETMLGDTAVAVNPE-------- 239
Cdd:PLN02843 171 WSPSSRTALAEAELEYpEGHVSKSIYVAFPVVSPSETspeeleeflpglSLAIWTTTPWTMPANAAVAVNDKlqysvvev 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 240 --------------DPRYGH--------------------------------------LVGKMLQLPLTERQIPIIAD-S 266
Cdd:PLN02843 251 qsfsedestsggnkKKRPGNvlkeqqklflivatdlvpaleakwgvklvvlktfpgsdLEGCRYIHPLYNRESPVVIGgD 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 267 YVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVIGMDGYMTEEAGKFAGQERY-ECRKNLVHELQEKGYLVKIEEHNH 345
Cdd:PLN02843 331 YITTESGTGLVHTAPGHGQEDYITGLKYGLPLLSPVDDAGKFTEEAGQFSGLSVLgEGNAAVVEALDEAGSLLMEEAYGH 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 346 AVGHCQRCRsviEPLV---SKQWFVKMEPLVKAAVDCVEdgRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWY 422
Cdd:PLN02843 411 KYPYDWRTK---KPTIfraTEQWFASVEGFRQAALDAID--KVKWIPAQGENRIRAMVSGRSDWCISRQRTWGVPIPVFY 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 423 CDACGEVIASRVDI-----------------------------DKCPKcggaVHQDEDALDTWFSSALwpfSTMGWPEKT 473
Cdd:PLN02843 486 HVETKEPLMNEETIahvksivaqkgsdawwymdvedllpekyrDKASD----YEKGTDTMDVWFDSGS---SWAGVLGSR 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 474 DLLKqfYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIE--------- 544
Cdd:PLN02843 559 EGLS--YPADLYLEGSDQHRGWFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGFKMSKSLGNVVDPRLVIEggknqkqep 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 545 KYGADTLRFMLITGNTPGnDMRFYWERVEATRNFANKIWNASRFALMNMEGYDAEaKQAPYT---LADQWILSRLQHTVK 621
Cdd:PLN02843 637 AYGADVLRLWVASVDYTG-DVLIGPQILKQMSDIYRKLRGTLRYLLGNLHDWKPD-NAVPYEdlpSIDKYALFQLENVVN 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 622 DVTELLGRFELGEAGRLIYDFIWSEVCDWYIELAKPRLY--NKEDPEARAtAQHVLAEVLTSAMKLLHPYMPFITEEIYQ 699
Cdd:PLN02843 715 EIEESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRLYvgGTTSFTRRS-CQTVLAAHLLSLLRAIAPILPHLAEDAWQ 793
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 815697062 700 CLPHESN-----SIMIAPWPIVDER-LFDDKAETGMTAimesikAIRNMRAEVNAA 749
Cdd:PLN02843 794 NLPFQEDgsaaeSVFEAGWPTPNEEwLSFPAEDVDFWS------LLLEVRDEVNKV 843
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
8-784 |
2.25e-77 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 273.91 E-value: 2.25e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 8 PKVYDPASVEKKWYKYWEEHRYFHAEVEADK-KP-FSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGY 85
Cdd:PLN02882 5 GKDFSFPKQEEKILSLWSEIDAFKTQLKRTEgLPeYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGW 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 86 DHAGLATQIKV---------EEVLKKEEGK---------TRYDLGREEFIKRVWEWkdkygdriieqlkslgvsCDWERK 147
Cdd:PLN02882 85 DCHGLPVEYEIdkklgikrrDDVLKMGIDKyneecrsivTRYSKEWEKTVTRTGRW------------------IDFEND 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 148 RFTMDEGCSQAVREVFVSLYEKGLIYQGSRITNWCVNCNTALSDIEV--EHEDDAGNLWYVRYPVVGEMETYLTIA-TTR 224
Cdd:PLN02882 147 YKTMDPKFMESVWWVFKQLFEKGLVYKGFKVMPYSTACKTPLSNFEAglNYKDVSDPAVMVSFPIVGDPDNASFVAwTTT 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 225 PETMLGDTAVAVNPE-------DPRYGH------------------------------------------LVGKMLQ--- 252
Cdd:PLN02882 227 PWTLPSNLALCVNPNftyvkvrNKYTGKvyivaesrlsalptakpkskkgskpenaaegyevlakvpgssLVGKKYEplf 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 253 ---LPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNL-----ESIVVIGMDGYMTEEAGKFAGQERYECR 324
Cdd:PLN02882 307 dyfSEFSDTAFRVVADDYVTDDSGTGVVHCAPAFGEDDYRVCLANGIiekggNLPVPVDDDGCFTEKVTDFSGRYVKDAD 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 325 KNLVHELQEKGYLVKIEEHNHAVGHCQRCRSviePLVSK---QWFVKMEPLVKAAVDCVEdgRTQFVPERFT-KTYTGWM 400
Cdd:PLN02882 387 KDIIAAIKAKGRLVKSGSITHSYPFCWRSDT---PLIYRavpSWFVKVEEIKDRLLENNK--QTYWVPDYVKeKRFHNWL 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 401 ENIRDWCISRQIWWGHRIPVWYCDACGEVI------------ASRVD------IDK--CPKC----GGAVHQDEDALDTW 456
Cdd:PLN02882 462 ENARDWAVSRSRFWGTPLPIWISDDGEEVVvigsiaeleklsGVKVTdlhrhfIDHitIPSSrgpeFGVLRRVDDVFDCW 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 457 FSSALWPFSTMGWP-EKTDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQGRKMSKSLGN 535
Cdd:PLN02882 542 FESGSMPYAYIHYPfENKELFEKNFPADFVAEGLDQTRGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKMSKSLKN 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 536 GIDPLEVIEKYGADTLRFMLItgNTP---GNDMRFYWERVEATRNFANKIW-NASRFALMNMEGYDAEA----------- 600
Cdd:PLN02882 622 YPDPNEVIDKYGADALRLYLI--NSPvvrAEPLRFKEEGVFGVVKDVFLPWyNAYRFLVQNAKRLEVEGgapfvpldlak 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 601 KQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwSEVCDWYIELAKPRLYNKEDPEARATAQHVLAEVLT 680
Cdd:PLN02882 700 LQNSANVLDRWINSATQSLVKFVREEMGAYRLYTVVPYLVKFI-DNLTNIYVRFNRKRLKGRTGEEDCRTALSTLYNVLL 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 681 SAMKLLHPYMPFITEEIYQ----CLPHESNSIMIAPWPIVDERLFDDKAETGMTAIMESIKAIRNMRAEVN---AAPGKK 753
Cdd:PLN02882 779 TSCKVMAPFTPFFTEVLYQnlrkVLPGSEESIHYCSFPQVDEGELDERIEQSVSRMQTVIELARNIRERHNkplKTPLKE 858
|
890 900 910
....*....|....*....|....*....|....*...
gi 815697062 754 VPAILL-------VNAELREIVEANKNYINLMGSIDEL 784
Cdd:PLN02882 859 MVVVHPdaeflddITGKLKEYVLEELNVRSLVPCNDPL 896
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
40-567 |
5.25e-74 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 245.02 E-value: 5.25e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 40 PFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKVEEvLKKEEGKTRYdlgREEFIKR 119
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAER-KGGRKKKTIW---IEEFRED 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 120 VWEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKGLIYQGSritnwcvncntalsdievehedd 199
Cdd:cd00668 77 PKEFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGT----------------------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 200 agnlwyvrypvvgemetyltiattrpetmlgdtavavnpedpryghlvgkmlqlplterqipiiadsyvdlefgtgavki 279
Cdd:cd00668 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 280 tpahdpndfemgmrhnlesivvigmdgymteeagkfagqeryecrknlvhelqekgYLVKIEEhnhavghcqrcrsviep 359
Cdd:cd00668 134 --------------------------------------------------------HPVRITE----------------- 140
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 360 lvskQWFVKMEPLVKAAVDCVEdgRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWYcdacgeviasrvdidkc 439
Cdd:cd00668 141 ----QWFFDMPKFKEKLLKALR--RGKIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLPEDV----------------- 197
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 440 pkcggavhqdedaLDTWFSSALWPFSTMGWPEKTDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHG 519
Cdd:cd00668 198 -------------FDVWFDSGIGPLGSLGYPEEKEWFKDSYPADWHLIGKDILRGWANFWITMLVALFGEIPPKNLLVHG 264
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 815697062 520 LVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRF 567
Cdd:cd00668 265 FVLDEGGQKMSKSKGNVIDPSDVVEKYGADALRYYLTSLAPYGDDIRL 312
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
11-720 |
9.81e-67 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 238.80 E-value: 9.81e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 11 YDPASVEKKWYKYWEEHRYFHAEVEADKKPFSIVI--PPPniTGQLHMGHALDNTLQDILIRWHRMMGDNTLwMP-GYDH 87
Cdd:COG0495 5 YNPKEIEKKWQKYWEENGTFKADEDSSKPKYYVLDmfPYP--SGRLHMGHVRNYTIGDVVARYKRMQGYNVL-HPmGWDA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 88 AGL-----AtqikveevlkkeegktrydlgreefIK-----RVWEWKDKygDRIIEQLKSLGVSCDWERK---------R 148
Cdd:COG0495 82 FGLpaenaA-------------------------IKngvhpAEWTYENI--ANMRRQLKRLGLSYDWSREiatcdpeyyK 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 149 FTmdegcsQAVrevFVSLYEKGLIYQGSRITNWCVNCNTALSDIEVEheDDAG----------NL--WY----------- 205
Cdd:COG0495 135 WT------QWI---FLQLYEKGLAYRKEAPVNWCPVDQTVLANEQVI--DGRCwrcgapvekkELpqWFlkitdyadell 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 206 ----------------------------VRYPVVGEMETyLTIATTRPETMLGDTAVAVNPEDPryghLVGKMLQL---- 253
Cdd:COG0495 204 ddldkldgwpekvktmqrnwigrsegaeVDFPVEGSDEK-ITVFTTRPDTLFGATFMVLAPEHP----LVKELATPeqna 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 254 -----------------------------------PLTERQIPI-IADsYVDLEFGTGAVKITPAHDPNDFEMGMRHNLE 297
Cdd:COG0495 279 avaafieeakkkseiertsetkektgvftglyainPLTGEKIPIwIAD-YVLMDYGTGAVMAVPAHDQRDFEFAKKYGLP 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 298 SIVVI----GMDGYMTEEA----------GKFAGQERYECRKNLVHELQEKGylvkieehnhaVGHcqrcrsvieplvsk 363
Cdd:COG0495 358 IKQVIapedGDDPDILEEAytgdgvlinsGEFDGLDSEEAKEAIIEWLEEKG-----------LGK-------------- 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 364 qwfvkmeplvkaavdcvedGRTQFvpeRftktytgwmenIRDWCISRQIWWGHRIPVWYCDACGEVIASR---------- 433
Cdd:COG0495 413 -------------------RKVNY---R-----------LRDWLISRQRYWGEPIPIIHCEDCGVVPVPEdqlpvelped 459
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 434 VDID----------------KCPKCGGAVHQDEDALDTWF-SSalW-------------PFStmgwPEKTDllkqfY--P 481
Cdd:COG0495 460 VDFDptggsplarapewvnvTCPKCGGPARRETDTMDTFVdSS--WyylrytdphndeaPFD----PEAAN-----YwlP 528
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 482 tsvlVTGYdiiffwvarmlIMGME--------------FMKDI-------PFDKVFIHGLVRD--------SQGRKMSKS 532
Cdd:COG0495 529 ----VDQY-----------IGGIEhailhllyarfftkVLRDLglvsfdePFKRLLTQGMVLEvgkdgvviGGIEKMSKS 593
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 533 LGNGIDPLEVIEKYGADTLR-FMLITGntPgndmrfyWER--------VEATRNFANKIWNasrfaLMNMEGYDAEAKQA 603
Cdd:COG0495 594 KGNVVDPDEIIEKYGADTLRlFEMFAG--P-------PERdlewsdsgVEGAYRFLNRVWR-----LVVDEAEALKLDVA 659
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 604 PYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwsevcdwyIELAKprlYNKEDPEARAtaqhVLAEVLTSAM 683
Cdd:COG0495 660 DLSEADKELRRALHKTIKKVTEDIERLRFNTAIAALMELV--------NALYK---AKDSGEADRA----VLREALETLV 724
|
890 900 910
....*....|....*....|....*....|....*..
gi 815697062 684 KLLHPYMPFITEEIYQCLPHESnSIMIAPWPIVDERL 720
Cdd:COG0495 725 LLLAPFAPHIAEELWERLGHEG-SVADAPWPEADEAA 760
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
567-701 |
1.37e-62 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 207.41 E-value: 1.37e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 567 FYWERVEATRNFANKIWNASRFALMNMEGYD-AEAKQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWS 645
Cdd:cd07962 1 FDEKRVEGGRNFCNKLWNAARFVLMNLEDDDePEEDPESLSLADRWILSRLNKTVEEVTEALENYRFSEAATALYEFFWN 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 815697062 646 EVCDWYIELAKPRLYNkEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL 701
Cdd:cd07962 81 DFCDWYLELVKPRLYG-EDEEEKKAARATLYYVLETILRLLHPFMPFITEELWQRL 135
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
47-567 |
4.77e-62 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 213.25 E-value: 4.77e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 47 PPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKVEEVLKKEEGKTRYDLGREEFIKRVWEWKDK 126
Cdd:cd00818 9 PPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGKKDIEKMGIAEFNAKCREFALR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 127 YGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKGLIYQGSRITNWcvncntalsdieveheddagnlwyv 206
Cdd:cd00818 89 YVDEQEEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW------------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 207 rypvvgemetyltiattrpetmlgdtavavnpedpryghlvgkmlqlplterqiPIIadsyvdlefgtgaVKITPahdpn 286
Cdd:cd00818 144 ------------------------------------------------------PLI-------------YRATP----- 151
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 287 dfemgmrhnlesivvigmdgymteeagkfagqeryecrknlvhelqekgylvkieehnhavghcqrcrsvieplvskQWF 366
Cdd:cd00818 152 -----------------------------------------------------------------------------QWF 154
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 367 VKMEPLVKAAVDCVEdgRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPVWYCDACGEVIASRVdidkcpkcggav 446
Cdd:cd00818 155 IRVTKIKDRLLEAND--KVNWIPEWVKNRFGNWLENRRDWCISRQRYWGTPIPVWYCEDCGEVLVRRV------------ 220
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 447 hqdEDALDTWFSSALWPFSTMGWPEKTDLLKQFYPTSVLVTGYDIIFFWVARMLIMGMEFMKDIPFDKVFIHGLVRDSQG 526
Cdd:cd00818 221 ---PDVLDVWFDSGSMPYAQLHYPFENEDFEELFPADFILEGSDQTRGWFYSLLLLSTALFGKAPYKNVIVHGFVLDEDG 297
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 815697062 527 RKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRF 567
Cdd:cd00818 298 RKMSKSLGNYVDPQEVVDKYGADALRLWVASSDVYAEDLRF 338
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
54-869 |
1.06e-54 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 204.72 E-value: 1.06e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 54 LHMGHALDNTLQDILIRWHRMMGDNTLWMPGYdHA------GLATQIK-----VEEVLKKEEGKTRYDLgrEEFiKRVWE 122
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAF-HVtgtpilGIAERIArgdpeTIELYKSLYGIPEEEL--EKF-KDPEY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 123 WKDKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKGLIYQGSRITNWCVNCNTALSDIEVEHEDDAGN 202
Cdd:PRK12300 77 IVEYFSEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGDHDLLDGEEPEI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 203 LWYVRYPVVGEMETYLTIATTRPETMLGDTAVAVNPE----------------------------------DPRYGHLVG 248
Cdd:PRK12300 157 VEYTLIKFEESEDLILPAATLRPETIFGVTNLWVNPDatyvkaevdgekwivskeaaeklsfqdrdveiieEIKGSELIG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 249 KMLQLPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDF----EMGMRHNL----ESIVVIGMDGY------------- 307
Cdd:PRK12300 237 KKVKNPVTGKEVPILPADFVDPDNGTGVVMSVPAHAPYDYvalrDLKKNKELldviEPIPLIEVEGYgefpakevveklg 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 308 -------------------------MTEEAGKFAGQERYECRKNLVHELQEKGYLVKIEE--HNHAVghCqRCRS-VIEP 359
Cdd:PRK12300 317 iksqedpeleeatkevyraefhkgvLKENTGEYAGKPVREAREKITKDLIEKGIADIMYEfsNRPVY--C-RCGTeCVVK 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 360 LVSKQWFVKM-EPLVKAAV-DCVEdgRTQFVPERFTKTYTGWMENIRDWCISRQIWWGHRIPvWycDAcGEVIASRVD-- 435
Cdd:PRK12300 394 VVKDQWFIDYsDPEWKELAhKALD--NMEIIPEEYRKEFENTIDWLKDRACARRRGLGTRLP-W--DE-EWIIESLSDst 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 436 -------IDKCPKCGG--AVHQDEDALDTWF---SSALWPFSTMGWPEKT--DLLKQF---YPTSVLVTGYDII-----F 493
Cdd:PRK12300 468 iymayytIAHKIREYGikPEQLTPEFFDYVFlgkGDPEEVSKKTGIPKEIleEMREEFlywYPVDWRHSGKDLIpnhltF 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 494 F------------WVARMLIMGMefmkdipfdkvfihGLVrdsQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTP 561
Cdd:PRK12300 548 FifnhvaifpeekWPRGIVVNGF--------------VLL---EGKKMSKSKGNVIPLRKAIEEYGADVVRLYLTSSAEL 610
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 562 GNDMRFYWERVEATRNFANKIWNasrFAlmnMEGYDAEAKQAPyTLADQWILSRLQHTVKDVTELLGRFELGEA-GRLIY 640
Cdd:PRK12300 611 LQDADWREKEVESVRRQLERFYE---LA---KELIEIGGEEEL-RFIDKWLLSRLNRIIKETTEAMESFQTRDAvQEAFY 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 641 DFiwSEVCDWYIELAkprlynkEDPEARataqhVLAEVLTSAMKLLHPYMPFITEEIYQCLPHEsNSIMIAPWPIVDERL 720
Cdd:PRK12300 684 EL--LNDLRWYLRRV-------GEANNK-----VLREVLEIWIRLLAPFTPHLAEELWHKLGGE-GFVSLEKWPEPDESK 748
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 721 FDDKAETGMTAIMESIKAIRNMRAEVNAAPgKKVpaillvnaelrEIVEANKNYINLMGSIDEliiddigAGKPENAMAA 800
Cdd:PRK12300 749 IDEEAELAEEYVKRLIEDIREILKVAKIKP-KKV-----------YIYVAPDWKYEVLEIAAE-------NGDVKEAIKE 809
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 801 VIAGIEVYLPLAgliDVEKETQRLNKELESMDKEI-KRVTGKLN-------NAGFLAKA--------PADVVEKEKAKAE 864
Cdd:PRK12300 810 LMKDEELRKHGK---EVAKLAQKIVKEVLKLDKEVrKLILKNIDeeevleeAKDFLEKElgveveiyGADDPGKKKKKKK 886
|
....*
gi 815697062 865 ELSGK 869
Cdd:PRK12300 887 ALPLK 891
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
17-701 |
2.38e-48 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 186.71 E-value: 2.38e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 17 EKKWYKYWEEHRYFHA--EVEADKKPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQI 94
Cdd:PTZ00427 78 EEKVLKYWKSIDAFNTsnKLAKNKKAYIFYDGPPFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFGWDCHGLPIEY 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 95 KVEE---VLKKEE-GKTRYDLGREEFIKRVWewkdKYGDRIIEQLKSLGVSCDWERKRFTMDEGCSQAVREVFVSLYEKG 170
Cdd:PTZ00427 158 EIEKennINKKEDiLKMGIDVYNEKCRGIVL----KYSNEWVKTVERIGRWIDFKNDYKTMDKTFMESVWWVFSELYKNN 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 171 LIYQGSRITNWCVNCNTALSDIE-------------------------VEHE---DDAGNLWYVRYPVV----------G 212
Cdd:PTZ00427 234 YVYKSFKVMPYSCKCNTPISNFElnlnykdtpdpsiiisfvlcsdfpkVEEEcniEEDKQLLGEKYSVLynnkrensnnG 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 213 E----------METYLTIATTRPETMLGDTAVAVNP----------------------------------ED-------- 240
Cdd:PTZ00427 314 NnnstnnvcyaQHSEILAWTTTPWTLPSNLALCVNEhftylrihhvksnrvvivgecrlewimkelkwnvEDlkivnrfk 393
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 241 ----------PRYGHLVGKMlqlPLTERQIPIIADSYVDLEFGTGAVKITPAHDPNDFEMGMRHNL----ESIVVIGMD- 305
Cdd:PTZ00427 394 gkelkglrykPLFTNFYEKY---NFKERAYKILADDFVTDDAGTGIVHCAPTYGEDDFRVCKKNGVidpeKNIFIDPLDa 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 306 -GYMTEEAGKFAGQERYECRKNLVHELQEKGYLVKIEEHNHAVGHCQRCRSviePLVSKQ---WFVKMEPLVKAAVDcvE 381
Cdd:PTZ00427 471 nGYFTNEVEEVQNLYIKEADNVIKKKLKNENRLLSNNTIVHSYPFCWRSDT---PLIYRAipaWFIRVSNSTNELVK--N 545
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 382 DGRTQFVPERFT-KTYTGWMENIRDWCISRQIWWGHRIPVWyCDA------CGEVIAS--------------RVDID--- 437
Cdd:PTZ00427 546 NETTYWIPAHIKeKKFHNWIKDAKDWCISRNRYWGTPIPIW-ADEkmetviCVESIKHleelsgvknindlhRHFIDhie 624
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 438 -KCPKcgGAVHQD----EDALDTWFSSALWPFSTMGWP---EKTDLLKQFyPTSVLVTGYDIIFFWVARMLIMGMEFMKD 509
Cdd:PTZ00427 625 iKNPK--GKTYPKlkriPEVFDCWFESGSMPYAKVHYPfstEKEDFHKIF-PADFIAEGLDQTRGWFYTLLVISTLLFDK 701
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 510 IPFDKVFIHGLVRDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITG-NTPGNDMRFYWERV-EATRNFANKIWNASR 587
Cdd:PTZ00427 702 APFKNLICNGLVLASDGKKMSKRLKNYPDPLYILDKYGADSLRLYLINSvAVRAENLKFQEKGVnEVVKSFILPFYHSFR 781
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 588 FALMNMEGYDAEAK-----QAPY-----TLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwSEVCDWYIELAKP 657
Cdd:PTZ00427 782 FFSQEVTRYECLNKkqflfNTDYiykndNIMDQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQFI-ENLTNWYIRLNRD 860
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 815697062 658 RLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL 701
Cdd:PTZ00427 861 RMRGSLGEENCLQSLCTTYRTLHLFTVLMAPFTPFITEYIYQQL 904
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
609-758 |
5.45e-43 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 152.94 E-value: 5.45e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 609 DQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWSEVCDWYIELAKPRLYNKEDPearATAQHVLAEVLTSAMKLLHP 688
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIKDRLYGEEPD---SRAQTTLYEVLETLLRLLAP 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 689 YMPFITEEIYQclpheSNSIMIAPWPiVDERLFDDKAETGMTAIMESIKAIRNMRAEVNAAPGKKVPAIL 758
Cdd:pfam08264 78 FMPFITEELWQ-----KESIHLAPWP-EDAELEEAELEEAFELRQEIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
3-723 |
8.42e-41 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 162.30 E-value: 8.42e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 3 EEHNIPKVYDPASVEKKWYKYWEEHRYFHA--EVEADKKPFSIV--IPPPNITGqLHMGHALDNTLQDILIRWHRMMGDN 78
Cdd:PLN02563 72 TTPAAKRAYPFHEIEPKWQRYWEENRTFRTpdDVDTSKPKFYVLdmFPYPSGAG-LHVGHPEGYTATDILARYKRMQGYN 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 79 TLWMPGYDHAGL-ATQIKVEEVLKKEEGKTRYDlgreefikrvwewkdkygDRIIEQLKSLGVSCDWERKRFTMDEGCSQ 157
Cdd:PLN02563 151 VLHPMGWDAFGLpAEQYAIETGTHPKITTLKNI------------------ARFRSQLKSLGFSYDWDREISTTEPEYYK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 158 AVREVFVSLYEKGLIYQGSRITNWCVNCNTALSDIEV-----------------------------------------EH 196
Cdd:PLN02563 213 WTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVvdglsergghpvirkpmrqwmlkitayadrlledlddldwpES 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 197 EDDAGNLWY-------VRYPVVG----EMETYLTIATTRPETMLGDTAVAVNPEDPRYGHLV------------------ 247
Cdd:PLN02563 293 IKEMQRNWIgrsegaeLDFSVLDgegkERDEKITVYTTRPDTLFGATYLVVAPEHPLLSSLTtaeqkeaveeyvdaasrk 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 248 -----------------GKMLQLPLTERQIPI-IADsYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESI-VVIGMDGYM 308
Cdd:PLN02563 373 sdlertelqkektgvftGSYAINPATGEAIPIwVAD-YVLGSYGTGAIMAVPAHDTRDFEFAQKFDLPIKwVVKPADGNE 451
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 309 TEeagkfagqeryecrknlvhelQEKGYlvkiEEHNHAVGHCQRCRSvIEPLVSKqwfvkmeplvKAAvdcvedgrtqfv 388
Cdd:PLN02563 452 DD---------------------AEKAY----TGEGVIVNSSSSGLD-INGLSSK----------EAA------------ 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 389 perftKTYTGWMENI-----------RDWCISRQIWWGHRIPVWYCDACGEVIA-------------------------- 431
Cdd:PLN02563 484 -----KKVIEWLEETgngkkkvnyklRDWLFARQRYWGEPIPVVFLEDSGEPVPvpesdlpltlpelddftptgtgeppl 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 432 -------SRVDidkcPKCGGAVHQDEDALDTWFSSALWPFSTMGwPEKTDLL------KQFYPTSVLVTGYD-----IIF 493
Cdd:PLN02563 559 akavswvNTVD----PSSGKPARRETNTMPQWAGSCWYYLRFMD-PKNSNALvdkekeKYWMPVDLYVGGAEhavlhLLY 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 494 --FWVARMLIMGMEFMKDiPFDKVFIHGLV---------RDSQGR----------------------------------- 527
Cdd:PLN02563 634 arFWHKVLYDIGVVSTKE-PFQCLVNQGMIlgeveytafKDSDGEyvsadtadrlgelqqekipeekviksgdsfvlkdd 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 528 ----------KMSKSLGNGIDPLEVIEKYGADTLR----FMlitgnTPGNDMRFYWER-VEATRNFANKIWNASRFALMN 592
Cdd:PLN02563 713 psirliarahKMSKSRGNVVNPDDVVSEYGADSLRlyemFM-----GPLRDSKTWSTSgVEGVHRFLGRTWRLVVGAPLP 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 593 MEGYDaEAKQAPYTLADQWILSRLQHTVKDVTELLG--RFELGEAGRLiyDFI-----WSEVcdwyielakPRlynkedp 665
Cdd:PLN02563 788 DGSFR-DGTVVTDEEPSLEQLRLLHKCIAKVTEEIEstRFNTAISAMM--EFTnaaykWDKV---------PR------- 848
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*...
gi 815697062 666 earataqhvlaEVLTSAMKLLHPYMPFITEEIYQCLPHeSNSIMIAPWPIVDERLFDD 723
Cdd:PLN02563 849 -----------EAIEPFVLLLSPYAPHLAEELWFRLGH-SNSLAYEPWPEANPSYLVD 894
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
45-701 |
4.34e-37 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 147.18 E-value: 4.34e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 45 IPPPNitGQLHMGHALDnTLQ-DILIRWHRMMGDNTLWMPGYD-HaGLATQIKVEEvlkkeEGKTRydlgrEEFIkrvwe 122
Cdd:COG0143 9 IPYAN--GPPHIGHLYT-YIPaDILARYQRLRGHDVLFVTGTDeH-GTKIELAAEK-----EGITP-----QELV----- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 123 wkDKYGDRIIEQLKSLGVSCDwerkRF--TMDEGCSQAVREVFVSLYEKGLIYQGSrITNW-CVNCntalsdievehedd 199
Cdd:COG0143 70 --DRIHAEFKELFEKLGISFD----NFirTTSPEHKELVQEIFQRLYDNGDIYKGE-YEGWyCPEC-------------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 200 agnlwyvrypvvgemETYLTiattrpetmlgdtavavnpedpryghlvgkmlqlplterqipiiaDSYVDlefGTGavki 279
Cdd:COG0143 129 ---------------ERFLP---------------------------------------------DRYVE---GTC---- 141
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 280 tpahdPNdfemgmrhnlesivvigmdgymteeaGKFAGQERYECRKNLVHelqekgyLVKIEEHNhavGHCQRCRSVIEP 359
Cdd:COG0143 142 -----PK--------------------------CGAEDAYGDQCENCGAT-------LEPTELIN---PRSAISGAPPEL 180
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 360 LVSKQWFVKM----EPLvKAAVDCVEDGRtqfvPERFTKTYtGWMEN-IRDWCISRQIWWG--------HRIPVWYcdac 426
Cdd:COG0143 181 REEEHYFFRLskyqDRL-LEWIEENPDIQ----PEVRNEVL-SWLKEgLQDLSISRDFDWGipvpgdpgKVFYVWF---- 250
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 427 geviasrvdidkcpkcggavhqdeDALDTWFSSalwpfsTMGWPEKT---DLLKQFYP----TSVLVTGYDIIFF----W 495
Cdd:COG0143 251 ------------------------DALIGYISA------TKGYADDRglpEDFEKYWPapdtELVHFIGKDIIRFhaiiW 300
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 496 VArMLiMGMEFmkdIPFDKVFIHG--LVRdsqGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRFYWERVE 573
Cdd:COG0143 301 PA-ML-MAAGL---PLPKKVFAHGflTVE---GEKMSKSRGNVIDPDDLLDRYGPDALRYYLLREVPFGQDGDFSWEDFV 372
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 574 ATRNF--ANKIWN-ASRFALM---NMEGYDAEAKqaPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwsEV 647
Cdd:COG0143 373 ARVNSdlANDLGNlASRTLSMihkYFDGKVPEPG--ELTEADEELLAEAEAALEEVAEAMEAFEFRKALEEIMALA--RA 448
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 815697062 648 CDWYIELAKP-RLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL 701
Cdd:COG0143 449 ANKYIDETAPwKLAKDEDPERLATVLYTLLEALRILAILLKPFLPETAEKILEQL 503
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
567-740 |
1.76e-36 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 135.76 E-value: 1.76e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 567 FYWERV-EATRNFANKIWNASRFALMNME--GYDAEAKQAPYTLA---DQWILSRLQHTVKDVTELLGRFELGEAGRLIY 640
Cdd:cd07961 1 FSEKGVrEVVRKVLLPLWNAYRFFVTYANldGFDPGKDDDAVASLnvlDRWILSRLNSLIKEVTEEMEAYDLYTAVRALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 641 DFIwSEVCDWYIELAKPRLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL----PHESNSIMIAPWPIV 716
Cdd:cd07961 81 EFI-DELTNWYIRRNRKRFWGEEGDDDKLAAYATLYEVLLTLSRLMAPFTPFITEEIYQNLrrelGDAPESVHLLDWPEV 159
|
170 180
....*....|....*....|....
gi 815697062 717 DERLFDDKAETGMTAIMESIKAIR 740
Cdd:cd07961 160 DESLIDEELEEAMELVREIVELGR 183
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
581-747 |
2.88e-27 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 109.15 E-value: 2.88e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 581 KIWNASRFALMNMEGYDAEAKQAPY---TLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWSEVCDWYIELAKP 657
Cdd:cd07960 15 KIRNTFRFLLGNLNDFDPAKDAVPYeelLELDRYALHRLNELIKEVREAYENYEFHKVYQALNNFCTVDLSAFYLDIIKD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 658 RLY-NKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPHESN--SIMIAPWPIVDERLFDDKaetgmtaIME 734
Cdd:cd07960 95 RLYcDAKDSLERRSAQTVLYHILDALLKLLAPILPFTAEEVWEHLPGEKKeeSVFLEDWPELPEEWKDEE-------LEE 167
|
170
....*....|...
gi 815697062 735 SIKAIRNMRAEVN 747
Cdd:cd07960 168 KWEKLLALRDEVN 180
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
39-706 |
7.49e-26 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 112.67 E-value: 7.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 39 KPFSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLatqiKVEevlKK--EEGKTrydlgreef 116
Cdd:PRK11893 1 KKFYITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFFLTGTDEHGQ----KIQ---RKaeEAGIS--------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 117 ikrVWEWKDKYGDRIIEQLKSLGVSCDwerkRF--TMDEGCSQAVREVFVSLYEKGLIYQGsRITNW-CVNCntalsdie 193
Cdd:PRK11893 65 ---PQELADRNSAAFKRLWEALNISYD----DFirTTDPRHKEAVQEIFQRLLANGDIYLG-KYEGWyCVRC-------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 194 veheddagnlwyvrypvvgemETYLTiattrpetmlgdtavavnPEDPRYGHLVGKMLQLPLTERQipiiADSYVdlefg 273
Cdd:PRK11893 129 ---------------------EEFYT------------------ESELIEDGYRCPPTGAPVEWVE----EESYF----- 160
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 274 tgavkitpahdpndFEMGmrhnlesivvigmdgymteeagkfAGQERyecrknlvheLQEKgylvkIEEHNHAVghcqRC 353
Cdd:PRK11893 161 --------------FRLS------------------------KYQDK----------LLEL-----YEANPDFI----QP 183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 354 RSVIEPLVSkqwFVKmeplvkaavdcvedgrtqfvperftktytgwmENIRDWCISRQ-IWWG--------HRIPVWYcd 424
Cdd:PRK11893 184 ASRRNEVIS---FVK--------------------------------SGLKDLSISRTnFDWGipvpgdpkHVIYVWF-- 226
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 425 acgeviasrvdidkcpkcggavhqdeDALDTWFSSALWPFSTmgwPEKTDLLKQFYPTSVLVTGYDIIFF----WVARML 500
Cdd:PRK11893 227 --------------------------DALTNYLTALGYPDDE---ELLAELFNKYWPADVHLIGKDILRFhavyWPAFLM 277
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 501 IMGMEFmkdipFDKVFIHG-LVRDsqGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRFYWERVEATRN-- 577
Cdd:PRK11893 278 AAGLPL-----PKRVFAHGfLTLD--GEKMSKSLGNVIDPFDLVDEYGVDAVRYFLLREIPFGQDGDFSREAFINRINad 350
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 578 FANKIWN-ASRFALMNMEGYDAEAKQ-APYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwsEVCDWYIELA 655
Cdd:PRK11893 351 LANDLGNlAQRTLSMIAKNFDGKVPEpGALTEADEALLEAAAALLERVRAAMDNLAFDKALEAILALV--RAANKYIDEQ 428
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 815697062 656 KPRLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCLPHESN 706
Cdd:PRK11893 429 APWSLAKTDPERLATVLYTLLEVLRGIAVLLQPVMPELAAKILDQLGVEED 479
|
|
| Val_tRNA-synt_C |
pfam10458 |
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA ... |
816-881 |
2.92e-25 |
|
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA synthetases.
Pssm-ID: 431296 [Multi-domain] Cd Length: 66 Bit Score: 99.26 E-value: 2.92e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 815697062 816 DVEKETQRLNKELESMDKEIKRVTGKLNNAGFLAKAPADVVEKEKAKAEELSGKMEAVKERLTYLA 881
Cdd:pfam10458 1 DVEKERARLEKELAKLQKEIERVQGKLANPGFVAKAPAEVVEEEKAKLAELEEQAEKLRERLSKLG 66
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
569-690 |
5.46e-19 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 83.32 E-value: 5.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 569 WERVEATRNFANKIWNASRFALMNMEGYDAEAKQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWSEvc 648
Cdd:cd07375 1 EERLKQARAFLNRLYRLLSFFRKALGGTQPKWDNELLEEADRELLARLQEFIKRTTNALEALDPTTAVQELFKFTNEL-- 78
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 815697062 649 DWYIELAKPRLYNKEDPEARATAQHVLAEVLTsamKLLHPYM 690
Cdd:cd07375 79 NWYLDELKPALQTEELREAVLAVLRAALVVLT---KLLAPFT 117
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
327-565 |
5.56e-18 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 85.76 E-value: 5.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 327 LVHELQEKGYLVKIEehnHAVGHCQRCRsvieplvskQWFVKMEP--LVKAAVDCVEdgRTQFVPERFTKTYTGWMEnir 404
Cdd:cd00812 106 LFLKLYEKGLAYKKE---APVNWCKLLD---------QWFLKYSEteWKEKLLKDLE--KLDGWPEEVRAMQENWIG--- 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 405 dwcISRQIWWGHRIPVwycdacgeviasrvdidkcpkcggavhqdEDALDTWFSSALWPFS-TMGW----PEKTDL---- 475
Cdd:cd00812 169 ---CSRQRYWGTPIPW-----------------------------TDTMESLSDSTWYYARyTDAHnleqPYEGDLefdr 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 476 --LKQFYPTSVLVTGYDII--------FFWVArmlIMGMEFMKDIPFDKVFIHGLVRdSQGRKMSKSLGNGIDPLEVIEK 545
Cdd:cd00812 217 eeFEYWYPVDIYIGGKEHApnhllysrFNHKA---LFDEGLVTDEPPKGLIVQGMVL-LEGEKMSKSKGNVVTPDEAIKK 292
|
250 260
....*....|....*....|
gi 815697062 546 YGADTLRFMLITGNTPGNDM 565
Cdd:cd00812 293 YGADAARLYILFAAPPDADF 312
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
45-587 |
1.30e-17 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 85.80 E-value: 1.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 45 IPPPNitGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKVEevlkkEEGKTrydlgREEFIkrvwewk 124
Cdd:pfam09334 7 LPYAN--GPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAE-----KEGIT-----PEELV------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 125 DKYGDRIIEQLKSLGVSCD-WERkrfTMDEGCSQAVREVFVSLYEKGLIYQGSrITNW-CVNCNTALSDIEVEheddaGN 202
Cdd:pfam09334 68 DRYHEIHREDFKKFNISFDdYGR---TTSERHHELVQEFFLKLYENGYIYEKE-IEQFyCPSDERFLPDRYVE-----GT 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 203 LWYVRYpvvgemetyltiattrpETMLGDtavavnpEDPRYGHLVgkmlqlplterqipiiadsyvdlefgtgavkitpa 282
Cdd:pfam09334 139 CPHCGS-----------------EDARGD-------QCENCGRHL----------------------------------- 159
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 283 hDPNDFEmgmrhNLESIVvigmdgymteeagkfagqeryeCRKNLVhelqekgylVKIEEHnhavghcqrcrsvieplvs 362
Cdd:pfam09334 160 -EPTELI-----NPKCVI----------------------CGTTPE---------VKETEH------------------- 183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 363 kqWFVKMEPLVKAAVDCVEDGRTQFvPERFTKTYTGWMEN-IRDWCISRQIWWGHRIP--------VWYcDACGEVIASR 433
Cdd:pfam09334 184 --YFFDLSKFQDKLREWIEENNPEW-PENVKNMVLEWLKEgLKDRAISRDLDWGIPVPgaegkvfyVWL-DAPIGYISAT 259
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 434 vdidKCPkCGgavhQDEDaldtWfsSALWPFstmgwpEKTDLLKQFyptsvlvTGYDIIFF----WVArMLIMGmefmkD 509
Cdd:pfam09334 260 ----KEL-SG----NEEK----W--KEWWPN------DPDTELVHF-------IGKDIIYFhtifWPA-MLLGA-----G 305
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 510 IPF-DKVFIHGLVrDSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRFYWERVEATRN--FANKIWN-A 585
Cdd:pfam09334 306 YRLpTTVFAHGYL-TYEGGKMSKSRGNVVWPSEALDRFPPDALRYYLARNRPETKDTDFSWEDFVERVNseLADDLGNlV 384
|
..
gi 815697062 586 SR 587
Cdd:pfam09334 385 NR 386
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
465-701 |
1.72e-17 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 87.16 E-value: 1.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 465 STMGWPEKTD-LLKQFYPTSVLVTGYDIIFF----WVArMLiMGMefmkDIP-FDKVFIHG-LVRDsqGRKMSKSLGNGI 537
Cdd:PRK12267 237 TALGYGSDDDeLFKKFWPADVHLVGKDILRFhaiyWPI-ML-MAL----GLPlPKKVFAHGwWLMK--DGKMSKSKGNVV 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 538 DPLEVIEKYGADTLRFMLITGNTPGNDMRF----YWERVEAtrNFANKIWN-ASRFALMNMEGYDAE-AKQAPYTLADQW 611
Cdd:PRK12267 309 DPEELVDRYGLDALRYYLLREVPFGSDGDFspeaLVERINS--DLANDLGNlLNRTVAMINKYFDGEiPAPGNVTEFDEE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 612 ILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwsEVCDWYIE------LAKprlyNKEDPEARATAQHVLAEVLTSAMKL 685
Cdd:PRK12267 387 LIALAEETLKNYEELMEELQFSRALEEVWKLI--SRANKYIDetapwvLAK----DEGKKERLATVMYHLAESLRKVAVL 460
|
250
....*....|....*.
gi 815697062 686 LHPYMPFITEEIYQCL 701
Cdd:PRK12267 461 LSPFMPETSKKIFEQL 476
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
45-567 |
2.16e-16 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 81.04 E-value: 2.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 45 IPPPNitGQLHMGHALDNTLQDILIRWHRMMGDNTLWMPGYDHAGLATQIKVEEvlkkeEGKTRydlgrEEFIkrvwewk 124
Cdd:cd00814 8 LPYVN--GVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEE-----EGVTP-----QELC------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 125 DKYGDRIIEQLKSLGVSCDwerkRF--TMDEGCSQAVREVFVSLYEKGLIYQGSrITNW-CVNCntalsdieveheddag 201
Cdd:cd00814 69 DKYHEIFKDLFKWLNISFD----YFirTTSPRHKEIVQEFFKKLYENGYIYEGE-YEGLyCVSC---------------- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 202 nlwyvrypvvgemETYLTIattrpetmlgdtavavnpedpryghlvgkmlqlplterqipiiadsyvdlefgtgavkitp 281
Cdd:cd00814 128 -------------ERFLPE------------------------------------------------------------- 133
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 282 ahdpndfemgmrhnlesivvigmdgymteeagkfagqeryecrknlvhelqekgylVKIEEHnhavghcqrcrsvieplv 361
Cdd:cd00814 134 --------------------------------------------------------WREEEH------------------ 139
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 362 skqWFVKMEPLVKAAVDCVEDGRTQFVPERFTKTYTGWMEN-IRDWCISRQIW-WGHRIP--------VW------YCDA 425
Cdd:cd00814 140 ---YFFRLSKFQDRLLEWLEKNPDFIWPENARNEVLSWLKEgLKDLSITRDLFdWGIPVPldpgkviyVWfdaligYISA 216
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 426 CGEVIasrvdidkcpkcggavhqDEDALDTWFSSalwpfstmGWPEktdllkqfyptSVLVTGYDIIFF----WVArMLi 501
Cdd:cd00814 217 TGYYN------------------EEWGNSWWWKD--------GWPE-----------LVHFIGKDIIRFhaiyWPA-ML- 257
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 815697062 502 MGMEFMkdiPFDKVFIHGLVRDSqGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRF 567
Cdd:cd00814 258 LGAGLP---LPTRIVAHGYLTVE-GKKMSKSRGNVVDPDDLLERYGADALRYYLLRERPEGKDSDF 319
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
398-701 |
7.37e-16 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 82.12 E-value: 7.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 398 GWMEN-IRDWCISRQI-WWGHRIP--------VWYcDACGEVIASRvdidkcpKCGGAVHQDEDALDTWFSSalwpfstm 467
Cdd:PRK00133 218 EWLEEgLQDWDISRDApYFGFEIPgapgkvfyVWL-DAPIGYISST-------KNLCDKRGGLDWDEYWKKD-------- 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 468 gwpEKTDLLkQFyptsvlvTGYDIIF----FWVArMLiMGMEFMKdiPfDKVFIHGLVRdSQGRKMSKSLGNGIDPLEVI 543
Cdd:PRK00133 282 ---SDTELY-HF-------IGKDIIYfhtlFWPA-ML-EGAGYRL--P-TNVFAHGFLT-VEGAKMSKSRGTFIWARTYL 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 544 EKYGADTLRFMLITgNTPGN--DMRFYWE----RVEAtrNFANKIWN-ASR---FALMNMEGydaeakQAPYTLADQWIL 613
Cdd:PRK00133 345 DHLDPDYLRYYLAA-KLPETidDLDFNWEdfqqRVNS--ELVGKVVNfASRtagFINKRFDG------KLPDALADPELL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 614 SRLQHTVKDVTELLGRFELGEAGRLIYdfiwsEVCDW---YIELAKPRLYNKEDPEARATAQHVLAEVLTSAMKLLHPYM 690
Cdd:PRK00133 416 EEFEAAAEKIAEAYEAREFRKALREIM-----ALADFankYVDDNEPWKLAKQDGERLQAVCSVGLNLFRALAIYLKPVL 490
|
330
....*....|.
gi 815697062 691 PFITEEIYQCL 701
Cdd:PRK00133 491 PELAERAEAFL 501
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
205-302 |
1.26e-10 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 61.41 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 205 YVRYPVVGeMETYLTIATTRPETMLGDTAVAVNPE----------DPRYGHLVGKMLQL--------------------- 253
Cdd:pfam13603 11 EITFPVEG-TDEKIEVFTTRPDTLMGVTFVALAPEhplveklaekNPEVAAFIEECKNTseiertsetkekegvftglya 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 815697062 254 --PLTERQIPI-IADsYVDLEFGTGAVKITPAHDPNDFEMGMRHNLESIVVI 302
Cdd:pfam13603 90 ihPITGEKIPIwIAN-FVLMEYGTGAVMAVPAHDQRDFEFAKKYNLPIKPVI 140
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
594-699 |
8.53e-10 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 57.22 E-value: 8.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 594 EGYDAEAKQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWSEVcDWYIELAKPRlYNKEdpearataqh 673
Cdd:cd07959 22 ELIETEGELEELTFIDRWLLSRLNRLIKETTEAYENMQFREALKEGLYELQNDL-DWYRERGGAG-MNKD---------- 89
|
90 100
....*....|....*....|....*.
gi 815697062 674 VLAEVLTSAMKLLHPYMPFITEEIYQ 699
Cdd:cd07959 90 LLRRFIEVWTRLLAPFAPHLAEEIWH 115
|
|
| Anticodon_Ia_Met |
cd07957 |
Anticodon-binding domain of methionyl tRNA synthetases; This domain is found in methionyl tRNA ... |
577-701 |
9.61e-10 |
|
Anticodon-binding domain of methionyl tRNA synthetases; This domain is found in methionyl tRNA synthetases (MetRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon (CAU). MetRS catalyzes the transfer of methionine to the 3'-end of its tRNA.
Pssm-ID: 153411 [Multi-domain] Cd Length: 129 Bit Score: 57.11 E-value: 9.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 577 NFANKIWNasrFALMNMEGYDAEAkqAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIWSevCDWYIELAK 656
Cdd:cd07957 11 NLVNRTLN---MASKYFGGVVPEF--GGLTEEDEELLEEAEELLEEVAEAMEELEFRKALEEIMELARA--ANKYIDETA 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 815697062 657 P-RLYNKEDPEARATAQHVLAEVLTSAMKLLHPYMPFITEEIYQCL 701
Cdd:cd07957 84 PwKLAKEEDPERLATVLYVLLELLRILAILLSPFMPETAEKILDQL 129
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
449-584 |
9.83e-10 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 62.04 E-value: 9.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 449 DEDALDTWFSSALWPFSTMGWPEKTDLLKQF----YPTSVLVTGYDIIFF----WVARMLIMGMEFMKdipfdKVFIHG- 519
Cdd:PLN02224 285 DKQTIYVWFDALLGYISALTEDNKQQNLETAvsfgWPASLHLIGKDILRFhavyWPAMLMSAGLELPK-----MVFGHGf 359
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 815697062 520 LVRDsqGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGNTPGNDMRFYWERVEATRN--FANKIWN 584
Cdd:PLN02224 360 LTKD--GMKMGKSLGNTLEPFELVQKFGPDAVRYFFLREVEFGNDGDYSEDRFIKIVNahLANTIGN 424
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
15-244 |
2.78e-08 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 57.77 E-value: 2.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 15 SVEKKWYKYWEEHRYFhaEVEADKKP------FSIVIPPPNITGQLHMGHALDNTLQDILIRWHRMMGDNTLW------- 81
Cdd:PLN02959 17 EIEVAVQKWWEEEKVF--EAEAGDEPpkpgekFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRLRGANVLLpfafhct 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 82 -MP---------------GY---------DHAGLATQIKVEE-----------------VLKKEEGKTRYDLGR-----E 114
Cdd:PLN02959 95 gMPikasadklareiqqyGNppvfpeedeDEAAAVAAAKAEAeaaaappdkfkgkkskaVAKSGTQKYQWEIMRsfglpD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 115 EFIKRV---WEWKDKYGDRIIEQLKSLGVSCDWERKRFTMDEG--CSQAVREVFVSLYEKGLIYQGSRITNW-------C 182
Cdd:PLN02959 175 SEIAKFqdpYHWLSYFPPLAKEDLKAFGLGCDWRRSFITTDVNpyYDAFVRWQFRKLKKKGKIVKDKRYTIYspldgqpC 254
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 815697062 183 VNCNTALSD---------IEVEheddagnlwyVRYPVVGEMET------YLTIATTRPETMLGDTAVAVNPeDPRYG 244
Cdd:PLN02959 255 ADHDRASGEgvgpqeyvlIKME----------VLPPFPGKLKAlegkkvFLAAATLRPETMYGQTNCWVLP-DGKYG 320
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
511-603 |
9.82e-08 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 55.49 E-value: 9.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 511 PFDKVFIH-GLVRDSqGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGN--TPGNdmrFYWERVEATRNFANKIWNASR 587
Cdd:COG0215 248 PFARYWMHnGFLTVN-GEKMSKSLGNFFTVRDLLKKYDPEVLRFFLLSAHyrSPLD---FSEEALEEAEKALERLYNALR 323
|
90
....*....|....*.
gi 815697062 588 FALMNMEGYDAEAKQA 603
Cdd:COG0215 324 RLEEALGAADSSAEEI 339
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
511-559 |
5.14e-06 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 48.34 E-value: 5.14e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 815697062 511 PFDKVFIH-GLVRdSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITGN 559
Cdd:cd00672 157 PFARYWLHtGHLT-IDGEKMSKSLGNFITVRDALKKYDPEVLRLALLSSH 205
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
572-699 |
4.52e-05 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 43.75 E-value: 4.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 572 VEATRNFANKIWnasRFALMNMEGYDAEAKQAPYTLADQWILSRLQHTVKDVTELLGRFELGEAGRLIYDFIwsevcdwy 651
Cdd:cd07958 6 VEGAYRFLNRVW---RLVTELAEALAAPAAAAELSEEDKELRRKLHKTIKKVTEDIERLRFNTAIAALMELV-------- 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 815697062 652 IELAKprlYNKEDPEARAtaqhVLAEVLTSAMKLLHPYMPFITEEIYQ 699
Cdd:cd07958 75 NALYK---YKKKDAQHAA----VLREALETLVLLLAPFAPHIAEELWE 115
|
|
| argS |
PRK01611 |
arginyl-tRNA synthetase; Reviewed |
496-572 |
2.25e-03 |
|
arginyl-tRNA synthetase; Reviewed
Pssm-ID: 234964 [Multi-domain] Cd Length: 507 Bit Score: 41.68 E-value: 2.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815697062 496 VARMLIMgMEFMKDIPFD-KVFIH---GLVRDSQGRKMSKSLGNGID-----------------PLEVIEKYGADTLRFM 554
Cdd:PRK01611 287 FKRLKAA-LKALGYDPDAlEVLLHqmvGLVRGGEGVKMSTRAGNVVTlddlldeavgrarelieEKEIAEAVGIDAVRYF 365
|
90
....*....|....*...
gi 815697062 555 LITgNTPGNDMRFYWERV 572
Cdd:PRK01611 366 DLS-RSRDKDLDFDLDLA 382
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
509-558 |
5.20e-03 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 40.04 E-value: 5.20e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 815697062 509 DIPFDKVFIH-GLVRdSQGRKMSKSLGNGIDPLEVIEKYGADTLRFMLITG 558
Cdd:pfam01406 234 DKQLANYWLHnGHVM-IDGEKMSKSLGNFFTIRDVLKRYDPEILRYFLLSV 283
|
|
| |
