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Conserved domains on  [gi|736058178|ref|WP_034201564|]
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MULTISPECIES: NAD(P)/FAD-dependent oxidoreductase [Burkholderia]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11457516)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
102-534 0e+00

FAD-dependent dehydrogenase [General function prediction only];


:

Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 748.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 102 RPVVIGMGPCGLFAGLILAQMGFRPIILERGKAVRERTKDTFGLWRKSVLNPESNVQFGEGGAGTFSDGKLYSQIKDPNH 181
Cdd:COG2509   32 DVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTCPVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNTRSKDPQG 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 182 YGRKVLDEFVKAGAPEDILYLSRPHIGTFRLVSMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLSNGETLRCDR 261
Cdd:COG2509  112 LIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIREYIEELGGEIRFNTRVTDILIEDGRVKGVVTNDGEEIEADA 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 262 VVLAVGHSARDTFQMLHDRGVYIEAKPFSLGFRIEHPQGLIDRSRFGKFAGHKQLGAADYKVVHHCSN-GRAVYSFCMCP 340
Cdd:COG2509  192 VILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQELIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRGVYTFCMCP 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 341 GGTVVAATSEPGRVVTNGMSQYSRAERNANAGIVVGITPDDYPGGPLAGIAFQRKWEERAFELGGGDYRAPGQLVGDFIA 420
Cdd:COG2509  272 GGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTPTDFPGGPLAGIEYQRSIERLANELGGGNYKAPAQRLGDFLA 351

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 421 GRPSTSLGSVEPSYKPGVNPTDLSTALPDYVIEAIREALPEIDKKIAGFAMHDAVLTGVETRTSSPIRIRRKDDYQSmNV 500
Cdd:COG2509  352 GRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREALEAFDKKIPGFASDDALLYGVETRTSSPVRIPRDEDLET-NI 430

                        410       420       430
                 ....*....|....*....|....*....|....
gi 736058178 501 EGLYPagegagyaggIYSAAIDGIEVAQAVALSL 534
Cdd:COG2509  431 KGLYPagegagyaggIVSAAVDGIRVAEAIAEKL 464
 
Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
102-534 0e+00

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 748.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 102 RPVVIGMGPCGLFAGLILAQMGFRPIILERGKAVRERTKDTFGLWRKSVLNPESNVQFGEGGAGTFSDGKLYSQIKDPNH 181
Cdd:COG2509   32 DVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTCPVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNTRSKDPQG 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 182 YGRKVLDEFVKAGAPEDILYLSRPHIGTFRLVSMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLSNGETLRCDR 261
Cdd:COG2509  112 LIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIREYIEELGGEIRFNTRVTDILIEDGRVKGVVTNDGEEIEADA 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 262 VVLAVGHSARDTFQMLHDRGVYIEAKPFSLGFRIEHPQGLIDRSRFGKFAGHKQLGAADYKVVHHCSN-GRAVYSFCMCP 340
Cdd:COG2509  192 VILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQELIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRGVYTFCMCP 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 341 GGTVVAATSEPGRVVTNGMSQYSRAERNANAGIVVGITPDDYPGGPLAGIAFQRKWEERAFELGGGDYRAPGQLVGDFIA 420
Cdd:COG2509  272 GGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTPTDFPGGPLAGIEYQRSIERLANELGGGNYKAPAQRLGDFLA 351

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 421 GRPSTSLGSVEPSYKPGVNPTDLSTALPDYVIEAIREALPEIDKKIAGFAMHDAVLTGVETRTSSPIRIRRKDDYQSmNV 500
Cdd:COG2509  352 GRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREALEAFDKKIPGFASDDALLYGVETRTSSPVRIPRDEDLET-NI 430

                        410       420       430
                 ....*....|....*....|....*....|....
gi 736058178 501 EGLYPagegagyaggIYSAAIDGIEVAQAVALSL 534
Cdd:COG2509  431 KGLYPagegagyaggIVSAAVDGIRVAEAIAEKL 464
PRK07233 PRK07233
hypothetical protein; Provisional
 104-266 2.30e-06

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 49.89  E-value: 2.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILER-----GKAVRERTKD----------------TFGLWRKsvLNPESNVQFGEG 162
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRGHEVTVFEAddqlgGLAASFEFGGlpierfyhhifksdeaLLELLDE--LGLEDKLRWRET 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 163 GAGTFSDGKLYS-----------------------------QIKDP-------------NHYGRKVLDEFV------KAG 194
Cdd:PRK07233  81 KTGYYVDGKLYPlgtplellrfphlslidkfrlglltllarRIKDWraldkvpaeewlrRWSGEGVYEVFWepllesKFG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 195 APED------------ILYLSRPHIGTFRL-------VSMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLsNGE 255
Cdd:PRK07233 161 DYADdvsaawlwsrikRRGNRRYSLFGEKLgyleggfATLIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEV-DGE 239

                        250
                 ....*....|.
gi 736058178 256 TLRCDRVVLAV 266
Cdd:PRK07233 240 EEDFDAVISTA 250
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 214-275 2.28e-04

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 43.63  E-value: 2.28e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736058178  214 SMVEKMRASIheLGGEVRFETRVDDIEIDQGKVRaLKLSNGETLRCDRVVLAV--GHSARDTFQ 275
Cdd:pfam01593 207 ALPDALAAQL--LGGDVRLNTRVRSIDREGDGVT-VTLTDGEVIEADAVIVTVplGVLKRILFT 267
 
Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
102-534 0e+00

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 748.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 102 RPVVIGMGPCGLFAGLILAQMGFRPIILERGKAVRERTKDTFGLWRKSVLNPESNVQFGEGGAGTFSDGKLYSQIKDPNH 181
Cdd:COG2509   32 DVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTCPVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNTRSKDPQG 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 182 YGRKVLDEFVKAGAPEDILYLSRPHIGTFRLVSMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLSNGETLRCDR 261
Cdd:COG2509  112 LIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIREYIEELGGEIRFNTRVTDILIEDGRVKGVVTNDGEEIEADA 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 262 VVLAVGHSARDTFQMLHDRGVYIEAKPFSLGFRIEHPQGLIDRSRFGKFAGHKQLGAADYKVVHHCSN-GRAVYSFCMCP 340
Cdd:COG2509  192 VILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQELIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRGVYTFCMCP 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 341 GGTVVAATSEPGRVVTNGMSQYSRAERNANAGIVVGITPDDYPGGPLAGIAFQRKWEERAFELGGGDYRAPGQLVGDFIA 420
Cdd:COG2509  272 GGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTPTDFPGGPLAGIEYQRSIERLANELGGGNYKAPAQRLGDFLA 351

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 421 GRPSTSLGSVEPSYKPGVNPTDLSTALPDYVIEAIREALPEIDKKIAGFAMHDAVLTGVETRTSSPIRIRRKDDYQSmNV 500
Cdd:COG2509  352 GRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREALEAFDKKIPGFASDDALLYGVETRTSSPVRIPRDEDLET-NI 430

                        410       420       430
                 ....*....|....*....|....*....|....
gi 736058178 501 EGLYPagegagyaggIYSAAIDGIEVAQAVALSL 534
Cdd:COG2509  431 KGLYPagegagyaggIVSAAVDGIRVAEAIAEKL 464
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 214-277 2.49e-10

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 62.94  E-value: 2.49e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736058178 214 SMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLSNGETLRCDRVVLAVghSARDTFQML 277
Cdd:COG1233  223 ALADALARLAEELGGEIRTGAEVERILVEGGRATGVRLADGEEIRADAVVSNA--DPAHTYLRL 284
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 220-270 6.46e-09

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 58.33  E-value: 6.46e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 736058178 220 RASIHELGGEVRFETRVDDIEIDQGKVRALKLSNGETLRCDRVVLAVGHSA 270
Cdd:COG3349  219 LAYLEARGGEVRLGTRVRALEFDGGRVTGLVLADGETVPADAVVLAVPPEV 269
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
104-280 1.33e-07

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 53.76  E-value: 1.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILERGKAVRERTKDTFGLWRKSVLNP--ESNVQFGEGGAGTFSD------------ 169
Cdd:COG0665    6 VVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALadRALVRLAREALDLWRElaaelgidcdfr 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 170 --GKLY--SQIKDPNHYgRKVLDEFVKAGAPEDIL----------YLSRPHI---------GTFRLVSMVEKMRASIHEL 226
Cdd:COG0665   86 rtGVLYlaRTEAELAAL-RAEAEALRALGLPVELLdaaelrerepGLGSPDYagglydpddGHVDPAKLVRALARAARAA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 736058178 227 GGEVRFETRVDDIEIDQGKVRALKLSNGeTLRCDRVVLAVGHSARDTFQMLHDR 280
Cdd:COG0665  165 GVRIREGTPVTGLEREGGRVTGVRTERG-TVRADAVVLAAGAWSARLLPMLGLR 217
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
109-271 1.72e-07

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 52.66  E-value: 1.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 109 GPCGLFAGLILAQMGFRPIILERGKAVRE---------RTKDTFGLWRKS--VLNPESNVQFgeggagTFSDGKlYSQIK 177
Cdd:COG0644    2 GPAGSAAARRLARAGLSVLLLEKGSFPGDkicgggllpRALEELEPLGLDepLERPVRGARF------YSPGGK-SVELP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 178 DPNHYG----RKVLDEFvkagapedilylsrphigtfrlvsmvekMRASIHELGGEVRFETRVDDIEIDQGKVRaLKLSN 253
Cdd:COG0644   75 PGRGGGyvvdRARFDRW----------------------------LAEQAEEAGAEVRTGTRVTDVLRDDGRVV-VRTGD 125

                        170
                 ....*....|....*...
gi 736058178 254 GETLRCDRVVLAVGHSAR 271
Cdd:COG0644  126 GEEIRADYVVDADGARSL 143
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 104-265 4.01e-07

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 51.86  E-value: 4.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILERGKAVRERTK------------DTFGLWRksvlnpesnvQFGEGGA----GTF 167
Cdd:COG0654    7 LIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRgialsprslellRRLGLWD----------RLLARGApirgIRV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 168 SDGklysqikdpnHYGRKVLDEFVKAGAPEDILYLSRPHIGTFrlvsmvekMRASIHELGGEVRFETRVDDIEIDQGKVR 247
Cdd:COG0654   77 RDG----------SDGRVLARFDAAETGLPAGLVVPRADLERA--------LLEAARALGVELRFGTEVTGLEQDADGVT 138

                        170
                 ....*....|....*...
gi 736058178 248 aLKLSNGETLRCDRVVLA 265
Cdd:COG0654  139 -VTLADGRTLRADLVVGA 155
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 104-270 1.47e-06

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 50.60  E-value: 1.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILER-----GKAVRERTK----DTFG------------LWRKsvLNPESNVQFGEG 162
Cdd:COG1232    5 AVIGGGIAGLTAAYRLAKAGHEVTVLEAsdrvgGLIRTVEVDgfriDRGPhsfltrdpevleLLRE--LGLGDELVWPNT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 163 GAGT-FSDGKLYS-------------------------------QIKDP--------NHYGRKVLDEFVK-------AGA 195
Cdd:COG1232   83 RKSYiYYGGKLHPlpqgplallrspllslagklrallellaprrPPGEDeslaefvrRRFGREVYERLVEpllegvyAGD 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 196 PEDI-----------LYLSR-----------------PHIGTFR--LVSMVEKMRASIHElgGEVRFETRVDDIEIDQGK 245
Cdd:COG1232  163 PDELsadwafprlkrLELEHgslikgalalrkgakagEVFGYLRggLGTLVEALAEALEA--GEIRLGTRVTAIEREGGG 240

                        250       260
                 ....*....|....*....|....*
gi 736058178 246 VRaLKLSNGETLRCDRVVLAVGHSA 270
Cdd:COG1232  241 WR-VTTSDGETIEADAVVSATPAPA 264
PRK07233 PRK07233
hypothetical protein; Provisional
 104-266 2.30e-06

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 49.89  E-value: 2.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILER-----GKAVRERTKD----------------TFGLWRKsvLNPESNVQFGEG 162
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRGHEVTVFEAddqlgGLAASFEFGGlpierfyhhifksdeaLLELLDE--LGLEDKLRWRET 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 163 GAGTFSDGKLYS-----------------------------QIKDP-------------NHYGRKVLDEFV------KAG 194
Cdd:PRK07233  81 KTGYYVDGKLYPlgtplellrfphlslidkfrlglltllarRIKDWraldkvpaeewlrRWSGEGVYEVFWepllesKFG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 195 APED------------ILYLSRPHIGTFRL-------VSMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLsNGE 255
Cdd:PRK07233 161 DYADdvsaawlwsrikRRGNRRYSLFGEKLgyleggfATLIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEV-DGE 239

                        250
                 ....*....|.
gi 736058178 256 TLRCDRVVLAV 266
Cdd:PRK07233 240 EEDFDAVISTA 250
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 92-278 1.12e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 47.94  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178  92 TKAPEHADFlrpVVIGMGPCGLFAGLILAQMGFRPIILERGKAVrertkdtFGLWRksvLN--PesnvqfgegGAGTFSD 169
Cdd:COG2072    1 TAATEHVDV---VVIGAGQAGLAAAYHLRRAGIDFVVLEKADDV-------GGTWR---DNryP---------GLRLDTP 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 170 GKLYSqikdpnhygrkvLDEFVKAGAPEDilYLSRPHIgtFR-LVSMVEKmrasiHELGGEVRFETRVDDIEIDQGKVR- 247
Cdd:COG2072   59 SHLYS------------LPFFPNWSDDPD--FPTGDEI--LAyLEAYADK-----FGLRRPIRFGTEVTSARWDEADGRw 117

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 736058178 248 ALKLSNGETLRCDRVVLAVGH---------SARDTF--QMLH 278
Cdd:COG2072  118 TVTTDDGETLTARFVVVATGPlsrpkipdiPGLEDFagEQLH 159
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
201-278 7.43e-05

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 45.33  E-value: 7.43e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 736058178 201 YLSRPHIGTFrLVSMVEKMRASIHELGGEVRFETRVDDIEIDQGKVRaLKLSNGETLRCDRVVLAVGHSARDTFQMLH 278
Cdd:COG4529   95 FVPRRLFGEY-LRERLAEALARAPAGVRLRHIRAEVVDLERDDGGYR-VTLADGETLRADAVVLATGHPPPAPPPGLA 170
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
104-271 7.60e-05

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 44.73  E-value: 7.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILERGkavrertkdtfglwrksvlnpesnvQFGeggagtfsdGKLySQIKDPNHYg 183
Cdd:COG0492    4 VIIGAGPAGLTAAIYAARAGLKTLVIEGG-------------------------EPG---------GQL-ATTKEIENY- 47

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 184 rkvldefvkAGAPEDILylsrphiGTfrlvSMVEKMRASIHELGGEVRFETrVDDIEIDQGKVRaLKLSNGETLRCDRVV 263
Cdd:COG0492   48 ---------PGFPEGIS-------GP----ELAERLREQAERFGAEILLEE-VTSVDKDDGPFR-VTTDDGTEYEAKAVI 105


                 ....*...
gi 736058178 264 LAVGHSAR 271
Cdd:COG0492  106 IATGAGPR 113
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 214-275 2.28e-04

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 43.63  E-value: 2.28e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 736058178  214 SMVEKMRASIheLGGEVRFETRVDDIEIDQGKVRaLKLSNGETLRCDRVVLAV--GHSARDTFQ 275
Cdd:pfam01593 207 ALPDALAAQL--LGGDVRLNTRVRSIDREGDGVT-VTLTDGEVIEADAVIVTVplGVLKRILFT 267
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
215-267 4.90e-04

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 42.55  E-value: 4.90e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 736058178 215 MVEKMRASIHELGGEVRFETRVDDIEIDQGKVRALKLSNG----ETLRCDRVVLAVG 267
Cdd:PRK08274 133 LVNALYRSAERLGVEIRYDAPVTALELDDGRFVGARAGSAaggaERIRAKAVVLAAG 189
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
104-131 1.19e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 41.43  E-value: 1.19e-03
                         10        20
                 ....*....|....*....|....*...
gi 736058178 104 VVIGMGPCGLFAGLILAQMGFRPIILER 131
Cdd:PRK06183  14 VIVGAGPVGLTLANLLGQYGVRVLVLER 41
PLN02612 PLN02612
phytoene desaturase
 223-266 3.05e-03

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 40.21  E-value: 3.05e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 736058178 223 IHELGGEVRFETRVDDIEI-DQGKVRALKLSNGETLRCDRVVLAV 266
Cdd:PLN02612 318 FQSLGGEVRLNSRIKKIELnDDGTVKHFLLTNGSVVEGDVYVSAT 362
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 188-268 4.60e-03

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 39.41  E-value: 4.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 736058178 188 DEFVKAGAPEDILYLSrPHIGTFRLVSMVEKMRASIHELGGEVRFETRVDDIEiDQGKVRAlKLSNGETLRCDRVVLAVG 267
Cdd:COG0446  141 EALRKRGLKVTLVERA-PRLLGVLDPEMAALLEEELREHGVELRLGETVVAID-GDDKVAV-TLTDGEEIPADLVVVAPG 217


                 .
gi 736058178 268 H 268
Cdd:COG0446  218 V 218
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
225-266 5.62e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 39.13  E-value: 5.62e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 736058178 225 ELGGEVRFETRVDDIEIDQGKVRaLKLSNGETLRCDRVVLAV 266
Cdd:COG1231  211 ELGDRIRLGAPVTRIRQDGDGVT-VTTDDGGTVRADAVIVTV 251
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
214-270 8.62e-03

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 38.58  E-value: 8.62e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 736058178 214 SMVEKMRASIHELGGEVRFETRVDdiEIDQGKVRalkLSNGETLRCDRVVLAVGHSA 270
Cdd:COG1252  204 KLSEAAEKELEKRGVEVHTGTRVT--EVDADGVT---LEDGEEIPADTVIWAAGVKA 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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