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Conserved domains on  [gi|501469549|ref|WP_012492994|]
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MULTISPECIES: PadR family transcriptional regulator [Burkholderia]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
81-160 1.07e-23

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 91.15  E-value: 1.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549  81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVASQAE-----GNRKRYALTDAGRAHLDAQRERVDTLF 155
Cdd:COG1695   18 LAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEeseggPRRKYYRLTEAGREELAEWLEEWEKLA 97


                 ....*
gi 501469549 156 ARLTH 160
Cdd:COG1695   98 EALEA 102
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
81-160 1.07e-23

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 91.15  E-value: 1.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549  81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVASQAE-----GNRKRYALTDAGRAHLDAQRERVDTLF 155
Cdd:COG1695   18 LAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEeseggPRRKYYRLTEAGREELAEWLEEWEKLA 97


                 ....*
gi 501469549 156 ARLTH 160
Cdd:COG1695   98 EALEA 102
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 81-144 5.05e-18

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 75.36  E-value: 5.05e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501469549   81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVASQAE-----GNRKRYALTDAGRAHL 144
Cdd:pfam03551   5 LGEQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVdsgggPPRKYYRLTDAGRREL 73
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 81-159 1.68e-09

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 53.33  E-value: 1.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549   81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVAS---QAEGNRKR--YALTDAGRAHLDAQRERvdtlF 155
Cdd:TIGR03433  13 LSLGPLHGYGIAQRIQQISEDVLQVEEGSLYPALHRLERRGWIAAewgESENNRRAkfYRLTAAGRKQLAAETES----W 88


                  ....
gi 501469549  156 ARLT 159
Cdd:TIGR03433  89 ARLS 92
lstR PRK09416
PadR family transcriptional regulator;
87-144 5.36e-03

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 35.92  E-value: 5.36e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549  87 HGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVAS--QAEGnRKRYALTDAGRAHL 144
Cdd:PRK09416  57 TGYELLQLLRQRGILTFEGNEGSLYTLLHRLEQNRFIQSswDHEG-AKYYQLTDKGNKML 115
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
81-160 1.07e-23

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 91.15  E-value: 1.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549  81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVASQAE-----GNRKRYALTDAGRAHLDAQRERVDTLF 155
Cdd:COG1695   18 LAEGPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEeseggPRRKYYRLTEAGREELAEWLEEWEKLA 97


                 ....*
gi 501469549 156 ARLTH 160
Cdd:COG1695   98 EALEA 102
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 81-144 5.05e-18

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 75.36  E-value: 5.05e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501469549   81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVASQAE-----GNRKRYALTDAGRAHL 144
Cdd:pfam03551   5 LGEQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVdsgggPPRKYYRLTDAGRREL 73
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 81-159 1.68e-09

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 53.33  E-value: 1.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549   81 VAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVAS---QAEGNRKR--YALTDAGRAHLDAQRERvdtlF 155
Cdd:TIGR03433  13 LSLGPLHGYGIAQRIQQISEDVLQVEEGSLYPALHRLERRGWIAAewgESENNRRAkfYRLTAAGRKQLAAETES----W 88


                  ....
gi 501469549  156 ARLT 159
Cdd:TIGR03433  89 ARLS 92
DUF4364 pfam14277
Domain of unknown function (DUF4364); This family of proteins is found in bacteria and archaea. ...
 113-158 1.28e-03

Domain of unknown function (DUF4364); This family of proteins is found in bacteria and archaea. Proteins in this family are approximately 180 amino acids in length.


Pssm-ID: 464122  Cd Length: 162  Bit Score: 38.24  E-value: 1.28e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 501469549  113 ALTYLEEVGFVASQAEGNRKRYALTDAGRAHLD--------AQRERVDTLFARL 158
Cdd:pfam14277  39 ALSELVESGLITEETTDNNTYYSITEKGKETLEyfenripySIREKIDAYLKEN 92
lstR PRK09416
PadR family transcriptional regulator;
87-144 5.36e-03

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 35.92  E-value: 5.36e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 501469549  87 HGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVAS--QAEGnRKRYALTDAGRAHL 144
Cdd:PRK09416  57 TGYELLQLLRQRGILTFEGNEGSLYTLLHRLEQNRFIQSswDHEG-AKYYQLTDKGNKML 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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