|
Name |
Accession |
Description |
Interval |
E-value |
| AMP_phos |
TIGR03327 |
AMP phosphorylase; This enzyme family is found, so far, strictly in the Archaea, and only in ... |
2-491 |
0e+00 |
|
AMP phosphorylase; This enzyme family is found, so far, strictly in the Archaea, and only in those with a type III Rubisco enzyme. Most of the members previously were annotated as thymidine phosphorylase, or DeoA. The AMP metabolized by this enzyme may be produced by ADP-dependent sugar kinases.
Pssm-ID: 274520 [Multi-domain] Cd Length: 494 Bit Score: 761.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 2 ELTVEPIDIGTERPVVLLNCADAETLGVHSLDRVEIDWDGTTEVGIVKVTDELVAAGRIGASHGFPE---ITDGTVVAVT 78
Cdd:TIGR03327 1 FLKVRPIDIKSGRYAVLLNEEDAKELGVHPGDRVRIESGGKSVVGIVASTDTLVEKGEIGLSHDVLEelgISEGEVVEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 79 PAGQPESVESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQPVV 158
Cdd:TIGR03327 81 PAGKPESVEYIKKKMDGEKLRKDEIRAIVADIVDDKLSDIEISAFVTASYINGMDMDEIEALTRAMAETGDMLSFDRHPI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 159 ADKHSIGGVAGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFCPVEFSREEIRDIVTETGGCLVWGGAVDLS 238
Cdd:TIGR03327 161 MDKHSIGGVPGNKISLLVVPIVAAAGLTIPKTSSRAITSAAGTADVMEVLAPVEFSLDEIKRIVEKTGGCLVWGGATNLA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 239 PVDDKVIRAQRPLSLDPPGQVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECALTRG 318
Cdd:TIGR03327 241 PADDKIIKVERPLSIDPRGQMLASVMAKKGAIGADHVVIDIPVGKGAKVETVEEGRKLARDFIELGDRLGMYVECAITYG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 319 SDPIGHGIGPVLEARDVLAVLEG-EGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAADILDSGAALSKFRDIVAVQGGD 397
Cdd:TIGR03327 321 GQPIGRAIGPALEAKEALKVLEDgEGPGSLIEKSLGLAGILLEMGGVAPRGEGKNLAKEILESGKALEKFKEIIAAQGGD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 398 PDVSRDDLQPGDRTETVTADTDGLVVDVDNQAVSQLARRAGAPNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAA 477
Cdd:TIGR03327 401 PDVKPEDIQVGDKTYTITAPTDGYVTDIDNKAITQIAREAGAPNDKGAGVYLHVKVGEKVKKGDPLYTIYAESEWRLENA 480
|
490
....*....|....
gi 499642952 478 REYAAGDEIVRVGG 491
Cdd:TIGR03327 481 IELARRLEPIKVEG 494
|
|
| PRK04350 |
PRK04350 |
thymidine phosphorylase; Provisional |
12-495 |
0e+00 |
|
thymidine phosphorylase; Provisional
Pssm-ID: 235289 [Multi-domain] Cd Length: 490 Bit Score: 663.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 12 TERPVVLLNCADA---ETLGVHSLDRVEIDWDGTTEVGIVKVTD-ELVAAGRIGASHGFPE---ITDGTVVAVTPAGQPE 84
Cdd:PRK04350 1 TGRENVIYNRRDAhvcRSEGFHAGDRVEVRAGGRSIIATLNITDdDLVGPGEIGLSESAFRrlgVSEGDEVEVSHAPPPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 85 SVESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQPVVADKHSI 164
Cdd:PRK04350 81 SLSAIRKKIDGEKLDKEEIEAIIRDIVAGRYSDIELSAFLTASAINGLDMDEIEALTRAMVETGERLDWDRPPVVDKHSI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 165 GGVAGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFCPVEFSREEIRDIVTETGGCLVWGGAVDLSPVDDKV 244
Cdd:PRK04350 161 GGVPGNRTTLIVVPIVAAAGLTIPKTSSRAITSPAGTADTMEVLAPVDLSVEEIKRVVEKVGGCLVWGGAVNLSPADDIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 245 IRAQRPLSLDPPGQVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECALTRGSDPIGH 324
Cdd:PRK04350 241 IRVERPLSIDPRGQLVASILSKKIAAGSTHVVIDIPVGPTAKVRSVEEARRLARLFEEVGDRLGLRVECAITDGSQPIGR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 325 GIGPVLEARDVLAVLEG--EGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAADILDSGAALSKFRDIVAVQGGDPdvsr 402
Cdd:PRK04350 321 GIGPALEARDVLAVLENdpDAPNDLREKSLRLAGILLEMGGVAPGGEGYALAREILESGKALEKFQEIIEAQGGDS---- 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 403 DDLQPGDRTETVTADTDGLVVDVDNQAVSQLARRAGAPNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAREYAA 482
Cdd:PRK04350 397 EDIPLGDHTHDVTAPRDGYVTAIDNRRLARIARLAGAPKDKGAGIDLHVKVGDKVKKGDPLYTIHAESEGELDYAIELAR 476
|
490
....*....|...
gi 499642952 483 GDEIVRVGGRDEA 495
Cdd:PRK04350 477 RHPPIIVEGMLLE 489
|
|
| DeoA |
COG0213 |
Thymidine phosphorylase [Nucleotide transport and metabolism]; Thymidine phosphorylase is part ... |
86-480 |
1.27e-59 |
|
Thymidine phosphorylase [Nucleotide transport and metabolism]; Thymidine phosphorylase is part of the Pathway/BioSystem: Pyrimidine salvage
Pssm-ID: 439983 [Multi-domain] Cd Length: 431 Bit Score: 202.19 E-value: 1.27e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 86 VESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQ---PVVaDKH 162
Cdd:COG0213 2 VDIIRKKRDGGELTAEEIRFFIDGYTDGSIPDYQMAAFLMAVYFRGMTDEETAALTLAMRDSGDVLDLSDipgPKV-DKH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 163 SIGGVaGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFcP---VEFSREEIRDIVTETGGCLVwGGAVDLSP 239
Cdd:COG0213 81 STGGV-GDKTSLVLAPLVAACGVPVPKMSGRGLGHTGGTLDKLESI-PgfrTELSEEEFRRQVNEIGCAII-GQTGDLAP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 240 VDdKVIRAQR---------PLsldppgqvIA-SVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGL 309
Cdd:COG0213 158 AD-KKLYALRdvtatvesiPL--------IAsSIMSKKLAAGADALVLDVKVGSGAFMKTLEDARELAESMVDIGNGAGR 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 310 TIECALTRGSDPIGHGIGPVLEARDVLAVLEGEGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAA-DILDSGAALSKFR 388
Cdd:COG0213 229 KTVALITDMNQPLGRAVGNALEVKEAIETLKGEGPEDLTELTLALGAEMLVLAGLAKDLEEARAKLeEALASGKALEKFK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 389 DIVAVQGGDPDVSRDD--LQPGDRTETVTADTDGLVVDVDNQAVSQLA-------RRAGAPNDHGAGVVIHRRTGDKAVA 459
Cdd:COG0213 309 EMVAAQGGDPDVVDDPelLPQAPVVREVKAPRSGYVSAIDARAIGLAAvllgagrATKEDPIDPAVGIVLLKKVGDKVEK 388
|
410 420
....*....|....*....|.
gi 499642952 460 GDVLYTIHAESSDRLEAAREY 480
Cdd:COG0213 389 GEPLATIHANDEADAEEAAER 409
|
|
| PYNP_C |
smart00941 |
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal ... |
422-483 |
5.75e-15 |
|
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal end of the large alpha/beta domain making up various pyrimidine nucleoside phosphorylases. It has slightly different conformations in different members of this family. For example, in pyrimidine nucleoside phosphorylase (PYNP) there is an added three-stranded anti-parallel beta sheet as compared to other members of the family, such as E. coli thymidine phosphorylase (TP). The domain contains an alpha/ beta hammerhead fold and residues in this domain seem to be important in formation of the homodimer.
Pssm-ID: 214925 [Multi-domain] Cd Length: 75 Bit Score: 69.49 E-value: 5.75e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499642952 422 VVDVDNQAVSQLARRAGA-------PNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAREYAAG 483
Cdd:smart00941 2 VTAIDARALGLAAVLLGAgrarkedPIDYGVGIVLHKKLGDRVKKGEPLATIHANDEAELEEAAEALRA 70
|
|
| PYNP_C |
pfam07831 |
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal ... |
422-481 |
1.94e-10 |
|
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal end of the large alpha/beta domain making up various pyrimidine nucleoside phosphorylases. It has slightly different conformations in different members of this family. For example, in pyrimidine nucleoside phosphorylase (PYNP) there is an added three-stranded anti-parallel beta sheet as compared to other members of the family, such as E. coli thymidine phosphorylase (TP). The domain contains an alpha/ beta hammerhead fold and residues in this domain seem to be important in formation of the homodimer.
Pssm-ID: 429685 [Multi-domain] Cd Length: 74 Bit Score: 56.81 E-value: 1.94e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499642952 422 VVDVDNQAVSQLARRAGA-------PNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAREYA 481
Cdd:pfam07831 2 VSSIDAREIGMAAMELGAgratktdPIDYGVGIYLHKKLGDKVKKGEPLATIYANDEIRLEEAVKKL 68
|
|
| MopB_CT_Tetrathionate_Arsenate-R |
cd02780 |
This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate ... |
16-66 |
7.87e-03 |
|
This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins.
Pssm-ID: 239181 [Multi-domain] Cd Length: 143 Bit Score: 36.89 E-value: 7.87e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 499642952 16 VVLLNCADAETLGVHSLDRVEIDWDGTTEVGIVKVTdELVAAGRIGASHGF 66
Cdd:cd02780 31 PVWINPEDAAKLGIKTGDRVRVVTPGGSVVGKAKVT-EGVRPGVVAIEHGY 80
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AMP_phos |
TIGR03327 |
AMP phosphorylase; This enzyme family is found, so far, strictly in the Archaea, and only in ... |
2-491 |
0e+00 |
|
AMP phosphorylase; This enzyme family is found, so far, strictly in the Archaea, and only in those with a type III Rubisco enzyme. Most of the members previously were annotated as thymidine phosphorylase, or DeoA. The AMP metabolized by this enzyme may be produced by ADP-dependent sugar kinases.
Pssm-ID: 274520 [Multi-domain] Cd Length: 494 Bit Score: 761.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 2 ELTVEPIDIGTERPVVLLNCADAETLGVHSLDRVEIDWDGTTEVGIVKVTDELVAAGRIGASHGFPE---ITDGTVVAVT 78
Cdd:TIGR03327 1 FLKVRPIDIKSGRYAVLLNEEDAKELGVHPGDRVRIESGGKSVVGIVASTDTLVEKGEIGLSHDVLEelgISEGEVVEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 79 PAGQPESVESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQPVV 158
Cdd:TIGR03327 81 PAGKPESVEYIKKKMDGEKLRKDEIRAIVADIVDDKLSDIEISAFVTASYINGMDMDEIEALTRAMAETGDMLSFDRHPI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 159 ADKHSIGGVAGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFCPVEFSREEIRDIVTETGGCLVWGGAVDLS 238
Cdd:TIGR03327 161 MDKHSIGGVPGNKISLLVVPIVAAAGLTIPKTSSRAITSAAGTADVMEVLAPVEFSLDEIKRIVEKTGGCLVWGGATNLA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 239 PVDDKVIRAQRPLSLDPPGQVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECALTRG 318
Cdd:TIGR03327 241 PADDKIIKVERPLSIDPRGQMLASVMAKKGAIGADHVVIDIPVGKGAKVETVEEGRKLARDFIELGDRLGMYVECAITYG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 319 SDPIGHGIGPVLEARDVLAVLEG-EGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAADILDSGAALSKFRDIVAVQGGD 397
Cdd:TIGR03327 321 GQPIGRAIGPALEAKEALKVLEDgEGPGSLIEKSLGLAGILLEMGGVAPRGEGKNLAKEILESGKALEKFKEIIAAQGGD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 398 PDVSRDDLQPGDRTETVTADTDGLVVDVDNQAVSQLARRAGAPNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAA 477
Cdd:TIGR03327 401 PDVKPEDIQVGDKTYTITAPTDGYVTDIDNKAITQIAREAGAPNDKGAGVYLHVKVGEKVKKGDPLYTIYAESEWRLENA 480
|
490
....*....|....
gi 499642952 478 REYAAGDEIVRVGG 491
Cdd:TIGR03327 481 IELARRLEPIKVEG 494
|
|
| PRK04350 |
PRK04350 |
thymidine phosphorylase; Provisional |
12-495 |
0e+00 |
|
thymidine phosphorylase; Provisional
Pssm-ID: 235289 [Multi-domain] Cd Length: 490 Bit Score: 663.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 12 TERPVVLLNCADA---ETLGVHSLDRVEIDWDGTTEVGIVKVTD-ELVAAGRIGASHGFPE---ITDGTVVAVTPAGQPE 84
Cdd:PRK04350 1 TGRENVIYNRRDAhvcRSEGFHAGDRVEVRAGGRSIIATLNITDdDLVGPGEIGLSESAFRrlgVSEGDEVEVSHAPPPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 85 SVESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQPVVADKHSI 164
Cdd:PRK04350 81 SLSAIRKKIDGEKLDKEEIEAIIRDIVAGRYSDIELSAFLTASAINGLDMDEIEALTRAMVETGERLDWDRPPVVDKHSI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 165 GGVAGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFCPVEFSREEIRDIVTETGGCLVWGGAVDLSPVDDKV 244
Cdd:PRK04350 161 GGVPGNRTTLIVVPIVAAAGLTIPKTSSRAITSPAGTADTMEVLAPVDLSVEEIKRVVEKVGGCLVWGGAVNLSPADDIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 245 IRAQRPLSLDPPGQVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECALTRGSDPIGH 324
Cdd:PRK04350 241 IRVERPLSIDPRGQLVASILSKKIAAGSTHVVIDIPVGPTAKVRSVEEARRLARLFEEVGDRLGLRVECAITDGSQPIGR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 325 GIGPVLEARDVLAVLEG--EGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAADILDSGAALSKFRDIVAVQGGDPdvsr 402
Cdd:PRK04350 321 GIGPALEARDVLAVLENdpDAPNDLREKSLRLAGILLEMGGVAPGGEGYALAREILESGKALEKFQEIIEAQGGDS---- 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 403 DDLQPGDRTETVTADTDGLVVDVDNQAVSQLARRAGAPNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAREYAA 482
Cdd:PRK04350 397 EDIPLGDHTHDVTAPRDGYVTAIDNRRLARIARLAGAPKDKGAGIDLHVKVGDKVKKGDPLYTIHAESEGELDYAIELAR 476
|
490
....*....|...
gi 499642952 483 GDEIVRVGGRDEA 495
Cdd:PRK04350 477 RHPPIIVEGMLLE 489
|
|
| ARCH_P_rylase |
TIGR02645 |
putative thymidine phosphorylase; Members of this family are closely related to characterized ... |
3-491 |
1.28e-176 |
|
putative thymidine phosphorylase; Members of this family are closely related to characterized examples of thymidine phosphorylase (EC 2.4.2.4) and pyrimidine nucleoside phosphorylase (RC 2.4.2.2). Most examples are found in the archaea, but other examples in Legionella pneumophila str. Paris and Rhodopseudomonas palustris CGA009.
Pssm-ID: 274245 [Multi-domain] Cd Length: 493 Bit Score: 505.47 E-value: 1.28e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 3 LTVEPIDIGTERPVVLLNCADAETLGVHSLDRVEIDWDGTTEVGIVKVTDELVAAGRIGASHGFPE---ITDGTVVAVTP 79
Cdd:TIGR02645 1 LKVRPLNIDTGQEHVLINSPDLRAEGFTPQDRVEVRIGGKSLIAILVGSDTLVEMGEIGLSVSAVEtfmAREGDIVTVTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 80 AGQPESVESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQPVVA 159
Cdd:TIGR02645 81 AEAPESLRAIRKKIDGAKLDQHEIASIVGDIVDERLSDVEISAFLTASAINGMTMDEIEALTIAMADTGEMLEWDREPIM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 160 DKHSIGGVAGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFCPVEFSREEIRDIVTETGGCLVWGGAVDLSP 239
Cdd:TIGR02645 161 DKHSIGGVPGNKTSLIVVPIVAAAGLLIPKTSSRAITSAAGTADTMEVLTRVALSAEEIKRIVEKVGGCLVWGGALNLAP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 240 VDDKVIRAQRPLSLDPPGQVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECALTRGS 319
Cdd:TIGR02645 241 ADDVLIRVERPLSIDPRAQMLASIMSKKIAAGSTHVLIDIPVGPGAKVRSLQEAERLARLFIELGDRLGVRVECAITYGS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 320 DPIGHGIGPVLEARDVLAVLE--GEGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAADILDSGAALSKFRDIVAVQGGD 397
Cdd:TIGR02645 321 QPIGRGIGPALEAKEALAVLErsPAAPFSLREKSLLLAGILLEMGGAAPRGAGKELARELLDSGKALEKMKEIIEAQGGD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 398 PdVSRDDLQPGDRTETVTADTDGLVVDVDNQAVSQLARRAGAPNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAA 477
Cdd:TIGR02645 401 P-NKSDDIEAGIYTADIHAETDGYVTEIDNKHITRIARLAGAPNDKGAGVELHVKVGDQVKKGDPLYTIYAESEGELDYA 479
|
490
....*....|....
gi 499642952 478 REYAAGDEIVRVGG 491
Cdd:TIGR02645 480 IALARRLNPIKVEG 493
|
|
| DeoA |
COG0213 |
Thymidine phosphorylase [Nucleotide transport and metabolism]; Thymidine phosphorylase is part ... |
86-480 |
1.27e-59 |
|
Thymidine phosphorylase [Nucleotide transport and metabolism]; Thymidine phosphorylase is part of the Pathway/BioSystem: Pyrimidine salvage
Pssm-ID: 439983 [Multi-domain] Cd Length: 431 Bit Score: 202.19 E-value: 1.27e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 86 VESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQ---PVVaDKH 162
Cdd:COG0213 2 VDIIRKKRDGGELTAEEIRFFIDGYTDGSIPDYQMAAFLMAVYFRGMTDEETAALTLAMRDSGDVLDLSDipgPKV-DKH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 163 SIGGVaGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFcP---VEFSREEIRDIVTETGGCLVwGGAVDLSP 239
Cdd:COG0213 81 STGGV-GDKTSLVLAPLVAACGVPVPKMSGRGLGHTGGTLDKLESI-PgfrTELSEEEFRRQVNEIGCAII-GQTGDLAP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 240 VDdKVIRAQR---------PLsldppgqvIA-SVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGL 309
Cdd:COG0213 158 AD-KKLYALRdvtatvesiPL--------IAsSIMSKKLAAGADALVLDVKVGSGAFMKTLEDARELAESMVDIGNGAGR 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 310 TIECALTRGSDPIGHGIGPVLEARDVLAVLEGEGPEPLRIKSLRLADIIFDMAREAGMPVDDRSAA-DILDSGAALSKFR 388
Cdd:COG0213 229 KTVALITDMNQPLGRAVGNALEVKEAIETLKGEGPEDLTELTLALGAEMLVLAGLAKDLEEARAKLeEALASGKALEKFK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 389 DIVAVQGGDPDVSRDD--LQPGDRTETVTADTDGLVVDVDNQAVSQLA-------RRAGAPNDHGAGVVIHRRTGDKAVA 459
Cdd:COG0213 309 EMVAAQGGDPDVVDDPelLPQAPVVREVKAPRSGYVSAIDARAIGLAAvllgagrATKEDPIDPAVGIVLLKKVGDKVEK 388
|
410 420
....*....|....*....|.
gi 499642952 460 GDVLYTIHAESSDRLEAAREY 480
Cdd:COG0213 389 GEPLATIHANDEADAEEAAER 409
|
|
| deoA |
PRK05820 |
thymidine phosphorylase; Reviewed |
86-483 |
8.53e-53 |
|
thymidine phosphorylase; Reviewed
Pssm-ID: 180276 [Multi-domain] Cd Length: 440 Bit Score: 184.64 E-value: 8.53e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 86 VESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQ-----PVVaD 160
Cdd:PRK05820 5 QEIIRKKRDGGALSDEEIDWFIDGYTDGTVSDGQIAALAMAIFFNGMTRPERVALTLAMRDSGEVLDWSSlnlngPIV-D 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 161 KHSIGGVaGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFcP---VEFSREEIRDIVTETGgCLVWGGAVDL 237
Cdd:PRK05820 84 KHSTGGV-GDKISLMLAPMVAACGGYVPMISGRGLGHTGGTLDKLEAI-PgyrAFPSNDRFREILKDVG-VAIIGQTSDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 238 SPVDdKVIRAQR---------PLsldppgqVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLG 308
Cdd:PRK05820 161 APAD-KRLYALRdvtatvesiPL-------ITASILSKKLAEGLDALVLDVKVGSGAFMKTYEEARELARSMVEVANGAG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 309 LTIECALTRGSDPIGHGIGPVLEARDVLAVLEGE-GPEPLRIKSLRLADIIFDMAREAGMPVDDR-SAADILDSGAALSK 386
Cdd:PRK05820 233 VRTTALLTDMNQPLASSAGNALEVREAVEFLTGGyRPPRLVEVTMALAAEMLVLAGLAKDEAEARaDLAAVLDSGKAAER 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 387 FRDIVAVQGGDPD-VSRDD--LQPGDRTETVTADTDGLVVDVDNQAVSQLA-------RRAGAPNDHGAGVVIHRRTGDK 456
Cdd:PRK05820 313 FGRMVAAQGGPPDfVENYDkyLPTAPHTKPVYADRSGVLSAMDTRALGMAVvrlgggrRRKGDPIDYSVGLTLHARLGDR 392
|
410 420
....*....|....*....|....*..
gi 499642952 457 AVAGDVLYTIHAESSDRLEAAREYAAG 483
Cdd:PRK05820 393 VDAGEPLATLHADDEERFQEAAAALKA 419
|
|
| PRK06078 |
PRK06078 |
pyrimidine-nucleoside phosphorylase; Reviewed |
86-468 |
1.12e-43 |
|
pyrimidine-nucleoside phosphorylase; Reviewed
Pssm-ID: 180387 [Multi-domain] Cd Length: 434 Bit Score: 159.87 E-value: 1.12e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 86 VESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQ--LSWEQPVVADKHS 163
Cdd:PRK06078 4 VDLIQKKRDGKELTTEEINFFIEGYTNGTIPDYQMSALAMAIYFKDMTDRERADLTMAMVNSGDTidLSAIEGIKVDKHS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 164 IGGVaGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVF--CPVEFSREEIRDIVTETGgCLVWGGAVDLSPVD 241
Cdd:PRK06078 84 TGGV-GDTTTLVLAPLVAAFGVPVAKMSGRGLGHTGGTIDKLESIkgFHVEISQEDFIKLVNENK-VAVIGQSGNLTPAD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 242 dKVIRAQRplslDPPGQV-----IAS-VLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECAL 315
Cdd:PRK06078 162 -KKLYALR----DVTATVnsiplIASsIMSKKIAAGADAIVLDVKTGAGAFMKTVEDAEELAHAMVRIGNNVGRNTMAVI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 316 TRGSDPIGHGIGPVLEARDVLAVLEGEGPEPLRIKSLRLADIIFDMAREAGMPVDDRSA-ADILDSGAALSKFRDIVAVQ 394
Cdd:PRK06078 237 SDMSQPLGRAIGNALEVLEAIDTLQGKGPKDLTELVLTLGSQMVVLAGKAKTLEEAREHlIEVMNNGKALEKFKEFLSAQ 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 395 GGDPDVSrDDL----QPGDRTEtVTADTDGLVVDVDNQAVSQLARRAGA-------PNDHGAGVVIHRRTGDKAVAGDVL 463
Cdd:PRK06078 317 GGDASVV-DDPeklpQAKYQIE-VPAKESGYISELVADEIGLAAMLLGAgratkedEIDLAVGIVLRKKVGDSVKKGESL 394
|
....*
gi 499642952 464 YTIHA 468
Cdd:PRK06078 395 ATIYA 399
|
|
| PYNP_C |
smart00941 |
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal ... |
422-483 |
5.75e-15 |
|
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal end of the large alpha/beta domain making up various pyrimidine nucleoside phosphorylases. It has slightly different conformations in different members of this family. For example, in pyrimidine nucleoside phosphorylase (PYNP) there is an added three-stranded anti-parallel beta sheet as compared to other members of the family, such as E. coli thymidine phosphorylase (TP). The domain contains an alpha/ beta hammerhead fold and residues in this domain seem to be important in formation of the homodimer.
Pssm-ID: 214925 [Multi-domain] Cd Length: 75 Bit Score: 69.49 E-value: 5.75e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499642952 422 VVDVDNQAVSQLARRAGA-------PNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAREYAAG 483
Cdd:smart00941 2 VTAIDARALGLAAVLLGAgrarkedPIDYGVGIVLHKKLGDRVKKGEPLATIHANDEAELEEAAEALRA 70
|
|
| PYNP_C |
pfam07831 |
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal ... |
422-481 |
1.94e-10 |
|
Pyrimidine nucleoside phosphorylase C-terminal domain; This domain is found at the C-terminal end of the large alpha/beta domain making up various pyrimidine nucleoside phosphorylases. It has slightly different conformations in different members of this family. For example, in pyrimidine nucleoside phosphorylase (PYNP) there is an added three-stranded anti-parallel beta sheet as compared to other members of the family, such as E. coli thymidine phosphorylase (TP). The domain contains an alpha/ beta hammerhead fold and residues in this domain seem to be important in formation of the homodimer.
Pssm-ID: 429685 [Multi-domain] Cd Length: 74 Bit Score: 56.81 E-value: 1.94e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499642952 422 VVDVDNQAVSQLARRAGA-------PNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAREYA 481
Cdd:pfam07831 2 VSSIDAREIGMAAMELGAgratktdPIDYGVGIYLHKKLGDKVKKGEPLATIYANDEIRLEEAVKKL 68
|
|
| Glycos_trans_3N |
pfam02885 |
Glycosyl transferase family, helical bundle domain; This family includes anthranilate ... |
86-148 |
4.78e-09 |
|
Glycosyl transferase family, helical bundle domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.
Pssm-ID: 460737 [Multi-domain] Cd Length: 63 Bit Score: 52.38 E-value: 4.78e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499642952 86 VESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVG 148
Cdd:pfam02885 1 KELIKKLRDGEDLTREEARAAMDGIMSGEATDAQIAAFLMALRMKGETAEEIAGLARAMRESG 63
|
|
| Glycos_transf_3 |
pfam00591 |
Glycosyl transferase family, a/b domain; This family includes anthranilate ... |
156-384 |
1.37e-06 |
|
Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.
Pssm-ID: 459860 [Multi-domain] Cd Length: 253 Bit Score: 49.59 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 156 PVVADKHSIGGVAGN--RVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVF-CPVEFSREEIRDIVTETGGCLVwg 232
Cdd:pfam00591 2 GDLVDIVGTGGDGDNtfNISTAAAIVAAACGVKVAKHGNRSVSSKSGSADVLEALgINLDLTPEQVRKLLDEVGVGFL-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 233 GAVDLSPVDDKVIRAQR------------PLS--LDPPGQVIaSVLSKKQSAGSSHIVVDIPYGAGAKVTS--LSEARDL 296
Cdd:pfam00591 80 FAPNYHPAMKHVAPVRRelgirtvfnllgPLInpARVKRQVL-GVYSKELAEGLAEVLKDLGRERAAVVHGdgLDEASLL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 297 ADDFRRVGDhLGLTIECALTRGSDPIGHGIGPVLE-------ARDVLAVLEGEGPEPLRIKSLRLADIIFDMAREAGMPV 369
Cdd:pfam00591 159 GKTTVAELK-DGEITEYTLTPEDFGLGRATLEALEggspkenADILKGVLGGKGSAAHRDLVALNAGAALYLAGKADSLK 237
|
250
....*....|....*.
gi 499642952 370 DDRS-AADILDSGAAL 384
Cdd:pfam00591 238 EGVAkALEVIDSGKAL 253
|
|
| DUF2254 |
pfam10011 |
Predicted membrane protein (DUF2254); Members of this family of bacterial proteins comprises ... |
350-478 |
6.20e-04 |
|
Predicted membrane protein (DUF2254); Members of this family of bacterial proteins comprises various hypothetical and putative membrane proteins. Their exact function, has not, as yet, been defined.
Pssm-ID: 430986 Cd Length: 370 Bit Score: 42.18 E-value: 6.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499642952 350 KSLRLADIIFDMAREAgmpvddRSAADILDSGAALSKFRDIVAVQGGDPDvsrDDLQPGDRTETVTADTDGLVVDVDNQA 429
Cdd:pfam10011 144 RSIQVSNIIARVGQET------LKAIDRLFPPELGGRPLEELPDDAPAPP---PEEPPPADATPIRAPRSGYLQAIDVDA 214
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 499642952 430 VSQLARragapnDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRLEAAR 478
Cdd:pfam10011 215 LVRLAE------EHDLVIRLEVRPGDFVVPGTPLARVWPPEVDDELAEE 257
|
|
| MopB_CT_Tetrathionate_Arsenate-R |
cd02780 |
This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate ... |
16-66 |
7.87e-03 |
|
This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins.
Pssm-ID: 239181 [Multi-domain] Cd Length: 143 Bit Score: 36.89 E-value: 7.87e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 499642952 16 VVLLNCADAETLGVHSLDRVEIDWDGTTEVGIVKVTdELVAAGRIGASHGF 66
Cdd:cd02780 31 PVWINPEDAAKLGIKTGDRVRVVTPGGSVVGKAKVT-EGVRPGVVAIEHGY 80
|
|
| |
