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Conserved domains on  [gi|489496008|ref|WP_003400924|]
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MULTISPECIES: GNAT family N-acetyltransferase [Mycobacterium]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10006981)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
116-199 3.87e-10

Predicted N-acetyltransferase YhbS [General function prediction only];


:

Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 55.86  E-value: 3.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489496008 116 MRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFRVTREIALPdAGPPLWA 195
Cdd:COG3153   59 VDIDGEGPALLLGPLAVDPEYRGQGIGRALMRAALEAARERGARAVVLLGDPSLLPFYERFGFRPAGELGLT-LGPDEVF 137


                 ....
gi 489496008 196 MWRE 199
Cdd:COG3153  138 LAKE 141
 
Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
116-199 3.87e-10

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 55.86  E-value: 3.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489496008 116 MRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFRVTREIALPdAGPPLWA 195
Cdd:COG3153   59 VDIDGEGPALLLGPLAVDPEYRGQGIGRALMRAALEAARERGARAVVLLGDPSLLPFYERFGFRPAGELGLT-LGPDEVF 137


                 ....
gi 489496008 196 MWRE 199
Cdd:COG3153  138 LAKE 141
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 114-180 8.21e-06

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 42.44  E-value: 8.21e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489496008  114 VMMRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFRV 180
Cdd:pfam13508  18 AALLPLDDEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAAAFYEKLGFEE 84
PLN02706 PLN02706
glucosamine 6-phosphate N-acetyltransferase
 133-179 3.21e-03

glucosamine 6-phosphate N-acetyltransferase


Pssm-ID: 178308 [Multi-domain]  Cd Length: 150  Bit Score: 36.61  E-value: 3.21e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 489496008 133 DPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFR 179
Cdd:PLN02706  94 DSAARGKGLGKKIIEALTEHARSAGCYKVILDCSEENKAFYEKCGYV 140
 
Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
116-199 3.87e-10

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 55.86  E-value: 3.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489496008 116 MRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFRVTREIALPdAGPPLWA 195
Cdd:COG3153   59 VDIDGEGPALLLGPLAVDPEYRGQGIGRALMRAALEAARERGARAVVLLGDPSLLPFYERFGFRPAGELGLT-LGPDEVF 137


                 ....
gi 489496008 196 MWRE 199
Cdd:COG3153  138 LAKE 141
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 114-184 4.07e-08

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 48.88  E-value: 4.07e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489496008 114 VMMRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCP-AYLEsTKPENVP---YYQRFGFRVTREI 184
Cdd:COG0456    3 ALLGLVDGGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARrLRLE-VREDNEAaiaLYEKLGFEEVGER 76
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 114-180 8.21e-06

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 42.44  E-value: 8.21e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489496008  114 VMMRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFRV 180
Cdd:pfam13508  18 AALLPLDDEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAAAFYEKLGFEE 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 114-189 1.69e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 42.67  E-value: 1.69e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489496008 114 VMMRVHPEEpHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPA-YLESTkPENVPYYQRFGFRVTREIALPDA 189
Cdd:COG1246   43 AALHPLDED-LAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRlFLLTT-SAAIHFYEKLGFEEIDKEDLPYA 117
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
117-201 3.87e-05

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 41.71  E-value: 3.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489496008 117 RVHPEEPHWylAAIG---SDPTVRGQGFGQVLMRSRLDRCDAEHC-PAYLESTKpENVPYYQRFGFRVTREIALpDAGPP 192
Cdd:COG2153   50 RLLPPGDGE--AKIGrvaVLPEYRGQGLGRALMEAAIEEARERGArRIVLSAQA-HAVGFYEKLGFVPVGEEFL-EAGIP 125


                 ....*....
gi 489496008 193 LWAMWREPR 201
Cdd:COG2153  126 HIDMRKPLS 134
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 118-178 7.29e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 40.58  E-value: 7.29e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489496008  118 VHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPEN---VPYYQRFGF 178
Cdd:pfam00583  53 IDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAADNlaaIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 121-184 5.22e-04

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 38.50  E-value: 5.22e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489496008 121 EEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCpAYLEST----KPENVPYYQRFGFRVTREI 184
Cdd:COG0454   55 DDKVLELKRLYVLPEYRGKGIGKALLEALLEWARERGC-TALELDtldgNPAAIRFYERLGFKEIERY 121
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
115-185 2.29e-03

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 35.65  E-value: 2.29e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489496008 115 MMRVHPEEPHW-YLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCP-AYLESTK--PENVPYYQRFGFRVTREIA 185
Cdd:COG3393    5 MAGVRAESPGVaEISGVYTHPEYRGRGLASALVAALAREALARGARtPFLYVDAdnPAARRLYERLGFRPVGEYA 79
PLN02706 PLN02706
glucosamine 6-phosphate N-acetyltransferase
 133-179 3.21e-03

glucosamine 6-phosphate N-acetyltransferase


Pssm-ID: 178308 [Multi-domain]  Cd Length: 150  Bit Score: 36.61  E-value: 3.21e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 489496008 133 DPTVRGQGFGQVLMRSRLDRCDAEHCPAYLESTKPENVPYYQRFGFR 179
Cdd:PLN02706  94 DSAARGKGLGKKIIEALTEHARSAGCYKVILDCSEENKAFYEKCGYV 140
Acetyltransf_9 pfam13527
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 126-180 4.85e-03

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 404421 [Multi-domain]  Cd Length: 124  Bit Score: 35.62  E-value: 4.85e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 489496008  126 YLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCP-AYLEstkPENVPYYQRFGFRV 180
Cdd:pfam13527  72 GITGVATYPEYRGRGVMSRLLRRSLEEMRERGVPlSFLY---PSSYPIYRRFGYEI 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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