|
Name |
Accession |
Description |
Interval |
E-value |
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
21-397 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 586.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIHVGSEPEQWSSmAVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTI 99
Cdd:pfam01053 1 DTLAVHAGQRPDPQTG-AVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAiTAAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 100 THLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVH 179
Cdd:pfam01053 80 LALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 180 KHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCN 259
Cdd:pfam01053 160 KHG--ILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 260 RGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFA 339
Cdd:pfam01053 238 RGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDNLKLFS 317
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 821595411 340 LAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:pfam01053 318 LAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQAL 375
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
18-400 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 579.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 18 KSFATDAIHVGSEPEqWSSMAVVPPISLSTTFKQHGP--------GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAV 89
Cdd:COG0626 1 MGPATRAVHAGRDPD-PQTGAVSPPIYLTSTFVFPSAealaarfaGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 90 ASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKV 168
Cdd:COG0626 80 ASGMAAiSAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 169 VDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGA 248
Cdd:COG0626 160 VDIAAIAAIAHAAG--ALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 249 VPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHA 328
Cdd:COG0626 238 VLSPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAA 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 821595411 329 STFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:COG0626 318 RRFLDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
38-397 |
0e+00 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 550.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFKQHGPGKHA--------GFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTITHLFKSGDG 108
Cdd:cd00614 2 AVAPPIYQTSTFVFPSPAEAAdlfalregGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAiSTVLLALLKAGDH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 109 ILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHnkDTIVV 188
Cdd:cd00614 82 VVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEH--GALLV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 189 VDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLR 268
Cdd:cd00614 160 VDNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 269 MKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYE 348
Cdd:cd00614 240 MERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVE 319
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 821595411 349 SLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:cd00614 320 SLVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQAL 368
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
9-399 |
6.93e-170 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 480.30 E-value: 6.93e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 9 SSAGFLPIYKSFATDAIHVGSEPEQWSSmAVVPPISLSTTFKQHGPGK-HAGFEYSRSGNPTRNCLEKAVAALDGAKYCL 87
Cdd:PRK07811 2 EDMSDHHANQGFATRAIHAGYEPDPATG-AVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 88 AVASGLAATLT-ITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTM 166
Cdd:PRK07811 81 AFSSGMAATDClLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 167 KVVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSL 246
Cdd:PRK07811 161 SITDIAALAELAHDAG--AKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 247 GAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLE 326
Cdd:PRK07811 239 GAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGEE 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 821595411 327 HASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEErkkLGISDTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:PRK07811 319 AARDFCARTKVFTLAESLGGVESLIEHPSAMTHASTAGSQ---LEVPDDLVRLSVGIEDVADLLADLEQALGQ 388
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
22-398 |
6.31e-150 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 429.53 E-value: 6.31e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 22 TDAIHVGSEPEQwSSMAVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTITH 101
Cdd:PRK07671 5 TKLIHGGIIGDP-STGAVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 102 LFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKH 181
Cdd:PRK07671 84 LFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 182 NkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRG 261
Cdd:PRK07671 164 G--LLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 262 LKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIkGKLEHASTFLSNLKLFALA 341
Cdd:PRK07671 242 LKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLA 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 821595411 342 ESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALG 398
Cdd:PRK07671 321 ESLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
19-399 |
4.71e-142 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 409.67 E-value: 4.71e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 19 SFATDAIHvGSEPEQWSSMAVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLT 98
Cdd:PRK06176 2 RMQTKLIH-GGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 99 ITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIV 178
Cdd:PRK06176 81 VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 179 HKHNKDTIVvvDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMC 258
Cdd:PRK06176 161 KDHGLLTIV--DNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 259 NRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKgKLEHASTFLSNLKLF 338
Cdd:PRK06176 239 QRGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLK-NDSEAVAFVESLKLF 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 821595411 339 ALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:PRK06176 318 ILGESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAK 378
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
20-397 |
2.31e-134 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 390.73 E-value: 2.31e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 20 FATDAIHVGSEPE-QWSSMAVvpPISLSTTF-----KQHG---PGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVA 90
Cdd:PRK06234 9 FATKAIHGGHIGDkQFGSLAT--PIYQTSTFifdsaEQGGrrfAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 91 SGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVV 169
Cdd:PRK06234 87 SGMGAiSSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 170 DIQACADIVHKHNKDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLIsLSRDDLYERLKF--LQNSLG 247
Cdd:PRK06234 167 DIKAISNIAHENNKECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFV-VGKEEFINQVKLfgIKDMTG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 248 AVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEH 327
Cdd:PRK06234 246 SVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEE 325
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 328 ASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:PRK06234 326 GKVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQAL 395
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
21-400 |
1.38e-131 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 382.64 E-value: 1.38e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIHVGSEPEQWSSMavVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTIT 100
Cdd:TIGR01329 2 STLLVNTDNKNDPYDAS--SMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVIT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 101 HLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHK 180
Cdd:TIGR01329 80 RLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 181 HNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNR 260
Cdd:TIGR01329 160 QN--ALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 261 GLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGcPGMITFYIKGKLEHASTFLSNLKLFAL 340
Cdd:TIGR01329 238 GIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKG-AGSVLSFETGSVALSKRLVEATKLFSI 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 341 AESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:TIGR01329 317 TVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFVTA 376
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
38-400 |
2.41e-130 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 379.91 E-value: 2.41e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTITHLFKSGDGILCMNDVY 116
Cdd:TIGR02080 21 CVVPPIYLSTTYNFTGFNEPRAYDYSRSGNPTRDLLQQALAELEGGAGAVVTNTGMSAiHLVTTALLGPDDLLVAPHDCY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 117 GGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIvhKHNKDTIVVVDNTFMSA 196
Cdd:TIGR02080 101 GGTYRLLNALAKKGCFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVDIAKICHL--AKAVGAVVVVDNTFLSP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 197 YFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNA 276
Cdd:TIGR02080 179 ALQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTLRGLRTLVARMRLQQRNA 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 277 LAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAI 356
Cdd:TIGR02080 259 QAIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGEQTVRRFLGGLSLFTLAESLGGVESLIAHPAT 338
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 821595411 357 MTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:TIGR02080 339 MTHAAMGPEARAEAGISDTLLRLSVGLEDADDLIADLEQGLRAA 382
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
19-400 |
4.91e-128 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 375.52 E-value: 4.91e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 19 SFATDAIHVGSEPEQwSSMAVVPPISLSTTFK----QHGP----GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVA 90
Cdd:COG2873 7 GFETLALHAGQEPDP-TTGARAVPIYQTTSYVfddaEHAAdlfaLKEPGNIYTRIMNPTTDVLEKRIAALEGGVAALATA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 91 SGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVV 169
Cdd:COG2873 86 SGQAAiTLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPALDVL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 170 DIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLI---------------SLSRDD 234
Cdd:COG2873 166 DIEAIAEIAHEHG--VPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIvdggnfdwaangkfpELTEPD 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 235 ------------------LYERLKFLQNsLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPG 296
Cdd:COG2873 244 psyhglvyteafgnaafiTKARVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYPG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 297 LPSHPQHELTKRQCT-GCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDT 375
Cdd:COG2873 323 LPSHPYHELAQKYLPkGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVTPD 402
|
410 420
....*....|....*....|....*
gi 821595411 376 LIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:COG2873 403 LIRLSVGIEDIDDIIADLDQALAAA 427
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
38-400 |
1.25e-126 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 369.80 E-value: 1.25e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTITHLFKSGDGILCMNDVYG 117
Cdd:PRK08247 22 TVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQLVMSLFRSGDELIVSSDLYG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 118 GTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAY 197
Cdd:PRK08247 102 GTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKIAKKHG--LLLIVDNTFYTPV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 198 FQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNAL 277
Cdd:PRK08247 180 LQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLLIRGMKTLALRMRQHEENAK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 278 AAAQFLEADPRVDRVIFPGlpshpqheltkrqcTGcpGMITFYIKgKLEHASTFLSNLKLFALAESLGGYESLAEHPAIM 357
Cdd:PRK08247 260 AIAAFLNEQPGVTDVLYPG--------------RG--GMLSFRLQ-DEEWVNPFLKSLKLITFAESLGGVESFITYPATQ 322
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 821595411 358 THASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08247 323 THADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFKQV 365
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
38-403 |
2.17e-124 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 364.86 E-value: 2.17e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTITHLFKSGDGILCMNDVYG 117
Cdd:PRK08064 24 AVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAFLLLSKGDHVLISEDVYG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 118 GTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHnkDTIVVVDNTFMSAY 197
Cdd:PRK08064 104 GTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKAI--GCLTFVDNTFLTPL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 198 FQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNAL 277
Cdd:PRK08064 182 LQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETAN 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 278 AAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKlEHASTFLSNLKLFALAESLGGYESLAEHPAIM 357
Cdd:PRK08064 262 KIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSE-EAVRQFVSHVKLPVFAVSLGAVESILSYPAKM 340
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 821595411 358 THASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAAHPK 403
Cdd:PRK08064 341 SHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEEP 386
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
18-401 |
4.34e-123 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 362.20 E-value: 4.34e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 18 KSFATDAIHVGSEPEQWSSmAVVPPISLSTTFK----QHG----PGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAV 89
Cdd:PRK07503 8 TGFSTRAIHHGYDPLDHGG-ALVPPVYLTATFAfptaEYGaecfAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVAL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 90 ASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKV 168
Cdd:PRK07503 87 ASGMGAiTATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 169 VDIQACADIVHKHnkDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYE-RLKFLQNSLG 247
Cdd:PRK07503 167 VDIAAVAEIAHGA--GAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRiRLEGLKDMTG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 248 AVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEH 327
Cdd:PRK07503 245 AVMSPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAA 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 821595411 328 ASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAAH 401
Cdd:PRK07503 325 GRRFMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALDACA 398
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
20-399 |
7.41e-123 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 361.13 E-value: 7.41e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 20 FATDAIHVGSEP-EQWSsmAVVPPISLSTTF-----KQHG---PGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVA 90
Cdd:TIGR01328 4 FATRAIHAGYPPkDQFG--ALTPPIYQTSTFvfdscEQGGnrfAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 91 SGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVV 169
Cdd:TIGR01328 82 SGMGAiAATLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 170 DIQACADIVHKhnKDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYE-RLKFLQNSLGA 248
Cdd:TIGR01328 162 DMERVCRDAHS--QGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRMVGIKDMTGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 249 VPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHA 328
Cdd:TIGR01328 240 VISPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAGA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 821595411 329 STFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:TIGR01328 320 KKLLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALDA 390
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
55-399 |
2.53e-114 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 339.28 E-value: 2.53e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 55 GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTIT-HLFKSGDGILCMNDVYGGTNRYFRKVASEVGLD 133
Cdd:PRK08133 48 GEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATASGMAAILAVVmALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIE 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 134 ISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSA 213
Cdd:PRK08133 128 TTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELADIAALAEIAHAAG--ALLVVDNCFCTPALQQPLKLGADVVIHSA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 214 TKYMNGHSDVVMGLISLSRDDLYERLKFLQnSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVI 293
Cdd:PRK08133 206 TKYLDGQGRVLGGAVVGSKELMEEVFGFLR-TAGPTLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVF 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 294 FPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGIS 373
Cdd:PRK08133 285 YPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAWRVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGIT 364
|
330 340
....*....|....*....|....*.
gi 821595411 374 DTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:PRK08133 365 EGLIRVAVGLEDVADIKADLARGLAA 390
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
17-397 |
8.06e-114 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 337.97 E-value: 8.06e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 17 YKSFATDAIHVGSEPEQWSSmAVVPPISLSTTF-----KQHG---PGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLA 88
Cdd:PRK06767 3 KKHMETALIHHGYTSEEHKG-SLTPPLFQTSTFtfetaQQGEasfAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 89 VASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMK 167
Cdd:PRK06767 82 FGSGMAAiSATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 168 VVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLG 247
Cdd:PRK06767 162 LIDLKQVIRVAKRNG--LLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 248 AVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFpglpshPQHELTKRQCTGCPGMITFYIKGKLEH 327
Cdd:PRK06767 240 GIMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEE 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 328 ASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:PRK06767 314 TQAFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQAL 383
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
38-397 |
4.57e-112 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 336.23 E-value: 4.57e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTITHLFKSGDGILCMNDVYG 117
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYG 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 118 GTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAY 197
Cdd:PLN02509 183 GSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQG--ALVLVDNSIMSPV 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 198 FQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNAL 277
Cdd:PLN02509 261 LSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENAR 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 278 AAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFyIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIM 357
Cdd:PLN02509 341 KIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFM 419
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 821595411 358 THASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:PLN02509 420 SHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
19-400 |
1.27e-111 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 333.11 E-value: 1.27e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 19 SFATDAIHVGSEPEQwSSMAVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TL 97
Cdd:PRK08776 12 SAATAAVRAGIDRDT-AYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAiNL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 98 TITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADI 177
Cdd:PRK08776 91 VLNALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 178 VHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLIsLSRD-DLYERLKFLQNSLGAVPSPFDCY 256
Cdd:PRK08776 171 AHKVG--ALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAV-VARDaELHQQLVWWANALGLTGSPFDAF 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 257 MCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLK 336
Cdd:PRK08776 248 LTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVDGLR 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 821595411 337 LFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08776 328 YFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGLARA 391
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
21-400 |
2.61e-107 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 321.07 E-value: 2.61e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIHVG-SEPEQWSsmAVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTI 99
Cdd:PRK08045 6 ATIAVRSGlNDDEQYG--CVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 100 THLF-KSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIV 178
Cdd:PRK08045 84 TTVFlKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 179 HKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMC 258
Cdd:PRK08045 164 REAG--AVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 259 NRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLF 338
Cdd:PRK08045 242 LRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLF 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 821595411 339 ALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08045 322 TLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAA 383
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
19-397 |
3.45e-107 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 322.00 E-value: 3.45e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 19 SFATDAIHVGSEPE-QWSSMAVvpPISLSTTFK----QHGPG----KHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAV 89
Cdd:TIGR01326 1 HFETLQLHAGQEPDpTTGSRAV--PIYQTTSYVfdstEHAAAlfglQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 90 ASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKV 168
Cdd:TIGR01326 79 ASGQAAiTYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 169 VDIQACADIVHKHnkDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSR---------------D 233
Cdd:TIGR01326 159 LDIEAIAEVAHRH--GIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVDGGkfdwnngrfplfttpD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 234 DLYERLKF----------------LQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGL 297
Cdd:TIGR01326 237 PSYHGLVFtetlgnpafilkarvqLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 298 PSHPQHELTKRQCTGCPG-MITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTL 376
Cdd:TIGR01326 317 ASHPHHALAKKYLPKGFGaVLSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGL 396
|
410 420
....*....|....*....|.
gi 821595411 377 IRLSVGLEDEEDIIADLDQAL 397
Cdd:TIGR01326 397 IRLSVGIENIDDIIADLEQAL 417
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
20-400 |
1.61e-106 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 319.76 E-value: 1.61e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 20 FATDAIHVGsEPEQWSSMAVVPPISLSTTFKQH--------GPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVAS 91
Cdd:PRK08249 9 VGTKAVWAG-EKEYLPYGATQVPVVLSVAYGYDdidewydvALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 92 GLAATLTITHLF-KSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVD 170
Cdd:PRK08249 88 GMAAISNTLYTFlKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 171 IQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVvMGLISLSRDDLYERLKFLQNSLGAVP 250
Cdd:PRK08249 168 IERLAAAAKKVG--ALVVVDNTFATPINQNPLALGADLVIHSATKFLSGHADA-LGGVVCGSKELMEQVYHYREINGATM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 251 SPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHAST 330
Cdd:PRK08249 245 DPMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKR 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 331 FLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08249 325 LLPKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHL 394
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
21-400 |
4.01e-106 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 318.38 E-value: 4.01e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIHVGSEPEQwSSMAVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTI 99
Cdd:PRK08861 7 ATIAVRTGIESDS-QYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSAlNLWV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 100 THLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVH 179
Cdd:PRK08861 86 SALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAK 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 180 KHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCN 259
Cdd:PRK08861 166 AVG--ALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 260 RGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFA 339
Cdd:PRK08861 244 RGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKVFVKALALFS 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 821595411 340 LAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08861 324 LAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQAFAKA 384
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
55-397 |
2.36e-105 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 316.02 E-value: 2.36e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 55 GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLT-ITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLD 133
Cdd:TIGR01325 41 GELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMAAIFAaLMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 134 ISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKhnKDTIVVVDNTFMSAYFQRPLALGADICMYSA 213
Cdd:TIGR01325 121 TVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAAVAELAHA--AGAKVVVDNVFATPLLQQPLKLGADVVVYSA 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 214 TKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVI 293
Cdd:TIGR01325 199 TKHIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPFNAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVY 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 294 FPGLPSHPQHELTKRQCTGCPGMITFYIKGKlEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGIS 373
Cdd:TIGR01325 279 YPGLPSHPQHELAKRQMSGGGTVVTFDLDCR-QAAFKVLDAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIG 357
|
330 340
....*....|....*....|....
gi 821595411 374 DTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:TIGR01325 358 DGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
38-397 |
8.89e-104 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 311.37 E-value: 8.89e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLTITHLFKSGDGILCMNDVYG 117
Cdd:PRK07269 24 ALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAIVLAFSVFPVGSKVVAVRDLYG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 118 GTNRYFRKVASEVGLDISFADLTklEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAY 197
Cdd:PRK07269 104 GSFRWFNQQEKEGRFHFTYANTE--EELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAKLAHAKG--AKVIVDNTFYSPI 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 198 FQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNAL 277
Cdd:PRK07269 180 YQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLMRGLKTLSLRMERSTANAQ 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 278 AAAQFLEADPRVDRVIFPGLpshpqheltkrqctgcPGMITFYI--KGKLEHastFLSNLKLFALAESLGGYESLAEHPA 355
Cdd:PRK07269 260 EVVAFLKKSPAVKEVLYTGK----------------GGMISFKVadETRIPH---ILNSLKVFTFAESLGGVESLITYPT 320
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 821595411 356 IMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:PRK07269 321 TQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQAL 362
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
21-399 |
4.74e-102 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 307.76 E-value: 4.74e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIHVGSEPEQWSSmaVVPPISLSTTFKQHGPGKHA--GFE--YSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA- 95
Cdd:PRK08574 4 GTDAVRGYRGSDPYGS--LQPPIYLTALFRQEGEAYPSdrGFDlkYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAi 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 96 -TLTIThLFKSGDGILCMNDVYGGTNRY---FRKVAseVGLDISFADLTKL-EELKAglkPNTKMVWIETPTNPTMKVVD 170
Cdd:PRK08574 82 sTLFFS-LLKAGDRVVLPMEAYGTTLRLlksLEKFG--VKVVLAYPSTEDIiEAIKE---GRTKLVFIETMTNPTLKVID 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 171 IqacaDIVHKHNKD--TIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGA 248
Cdd:PRK08574 156 V----PEVAKAAKElgAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGT 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 249 VPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRqCTGCP---GMITFYIKGKL 325
Cdd:PRK08574 232 IMQPFEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKR-LFGKDlygGVVSFRVKGGR 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 821595411 326 EHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:PRK08574 311 DAVLKFLRSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQALGS 384
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
16-399 |
2.50e-100 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 303.36 E-value: 2.50e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 16 IYKSFATDAIHVGS--EPEQWSsmaVVPPISLSTTFKQHGPGKHAGFE--------YSRSGNPTRNCLEKAVAALDGAKY 85
Cdd:PRK06434 5 MLNGFNTRAVQSGElrDPRFGN---VTTPIFETSTFVYPNSEKEAYMDstrgmpyiYTRWGNPTVQAFEEKYAVLENAEH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 86 CLAVASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKagLKP-NTKMVWIETPTN 163
Cdd:PRK06434 82 ALSFSSGMGAiTSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLD--FDPsNYDLIYAESITN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 164 PTMKVVDIQACADIVHKHNkdtiVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQ 243
Cdd:PRK06434 160 PTLKVPDIKNVSSFCHEND----VIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 244 NSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLpshpqhELTKRQCTGCPGMITFYIKg 323
Cdd:PRK06434 236 KTLGSNPDPIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELR- 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 821595411 324 KLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:PRK06434 309 SMEDVHKFIRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
28-400 |
5.35e-96 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 293.50 E-value: 5.35e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 28 GSEPEqWSSMAVVPPISLSTTF------------------KQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAV 89
Cdd:PRK07049 26 GYDPE-LSEGAVKPPVFLTSTFvfrsaedgrdffdyvsgrKEPPAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALF 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 90 ASGLAATLTITHLF-KSGDGILCMNDVYGGTNRYFRKVASEVGLD-ISFADLTKLEELKAGL-----KPNTKMVWIETPT 162
Cdd:PRK07049 105 SSGMSAIATTLLAFvRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaaKGRVSLILIETPA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 163 NPTMKVVDIQAC---AD-IVHKHNKDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLIsLSRDDLYER 238
Cdd:PRK07049 185 NPTNSLVDVAAVrrvADaIEARQGHRPIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAV-LGRKALIRQ 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 239 LKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGL--PSHPQHELTKRQCTGCPGM 316
Cdd:PRK07049 264 VRALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGAVYKRQCTGAGST 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 317 ITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQA 396
Cdd:PRK07049 344 FSFDIKGGQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQA 423
|
....
gi 821595411 397 LGAA 400
Cdd:PRK07049 424 LDAA 427
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
55-400 |
3.62e-90 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 277.79 E-value: 3.62e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 55 GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLD 133
Cdd:PRK07504 52 GEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAvTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 134 ISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNKDtiVVVDNTFMSAYFQRPLALGADICMYSA 213
Cdd:PRK07504 132 STLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGAK--LVVDNVFATPLFQKPLELGAHIVVYSA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 214 TKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVI 293
Cdd:PRK07504 210 TKHIDGQGRCLGGVVLSDKAWIEEHLQDYFRHTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVI 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 294 FPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGIS 373
Cdd:PRK07504 290 YPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGIS 369
|
330 340
....*....|....*....|....*..
gi 821595411 374 DTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK07504 370 EGFLRLSAGLEDTDDLIEDLAAALKKV 396
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
20-400 |
2.45e-89 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 276.59 E-value: 2.45e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 20 FATDAIHVGSEPEQwSSMAVVPPISLSTTFKQHGPgKHA---------GFEYSRSGNPTRNCLEKAVAALDGAKYCLAVA 90
Cdd:PRK05994 8 FATLAVHAGAQPDP-TTGARATPIYQTTSFVFNDA-DHAaslfglqafGNIYTRITNPTNAVLEERVAALEGGTAALAVA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 91 SGLAATLTITH-LFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVV 169
Cdd:PRK05994 86 SGHAAQFLVFHtLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 170 DIQACADIVHKHNKDTIvvVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLI------SLSRDDLYERLK--- 240
Cdd:PRK05994 166 DIAAIAEVAHRAGLPLI--VDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIvdggtfDWSKSGKYPMLSepr 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 241 ------FLQNS-----------------LGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGL 297
Cdd:PRK05994 244 peyhglVLHETfgnfafaiaarvlglrdLGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 298 PSHPQHELTKRQCTGCPGMI-TFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTL 376
Cdd:PRK05994 324 PDDPYHALAQKYSPKGAGAVfTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDV 403
|
410 420
....*....|....*....|....
gi 821595411 377 IRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK05994 404 VRLSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
22-400 |
8.97e-89 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 275.18 E-value: 8.97e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 22 TDAIHVGSEPEQWS-SMAVvpPISLSTTF----KQHGPG----KHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASG 92
Cdd:PRK08248 11 TLAIHAGQEIDPTTgSRAV--PIYQTTSYgfrdSEHAANlfslKEFGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 93 LAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDI 171
Cdd:PRK08248 89 QAAiTYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 172 QACADIVHKHNKDTIVvvDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLI---------------SLSRDD-- 234
Cdd:PRK08248 169 EAVAAIAHEHGIPLIV--DNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIvdsgkfdwkgsgkfpGLTEPDps 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 235 ----------------LYERLKFLQNsLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLP 298
Cdd:PRK08248 247 yhglvytdavgeaayiTKARVQLLRD-LGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLP 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 299 SHPQHELTKRQCTGCPGMI-TFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLI 377
Cdd:PRK08248 326 SHPSYELAKKYLPKGQGAIlTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLV 405
|
410 420
....*....|....*....|...
gi 821595411 378 RLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08248 406 RLSVGTEAIDDILDDLRQAIRQS 428
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
22-400 |
2.11e-87 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 271.39 E-value: 2.11e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 22 TDAIHVGSEPEQwSSMAVVPPISLSTTF----KQHGPG----KHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGL 93
Cdd:PRK06084 5 TLAIHAGYSPDP-TTKAVAVPIYQTTSYafddTQHGADlfdlKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVASGM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 94 AA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQ 172
Cdd:PRK06084 84 AAiTYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDIQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 173 ACADIVHKHNKDTIVvvDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLS-----------------RDDL 235
Cdd:PRK06084 164 ALADAAHRHGVPLIV--DNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVDSgkfpwaehkerfallntPDPS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 236 YERLKFLQN----------------SLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPS 299
Cdd:PRK06084 242 YHGVTYTEAfgpaafigrcrvvplrNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 300 HPQHELTKRQCTGCP-GMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIR 378
Cdd:PRK06084 322 HPEHELARRYMGGKPaSILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVR 401
|
410 420
....*....|....*....|..
gi 821595411 379 LSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK06084 402 LSIGIEHIDDIIADLAQALDAS 423
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
38-397 |
2.64e-87 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 269.78 E-value: 2.64e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 38 AVVPPISLSTTFkqHGPGKHAgFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTITHLFKSGDGILCMNDVY 116
Cdd:PRK06460 18 AITTPIYQTTAY--HYPEGEK-YRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAiSTTALALLKPGNSVLVHRDMF 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 117 GGTNRYFRKVASEVGLDISFA---DLTKLEELKAglkPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTF 193
Cdd:PRK06460 95 GRSYRFFTDYLKNWGVNVDASnpgSDNIIEKAKS---KRYDVVFVENITNPLLRVVDITELSKVCKENG--SILIVDATF 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 194 MSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDdLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHF 273
Cdd:PRK06460 170 STPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGK-LLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVIN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 274 KNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEH 353
Cdd:PRK06460 249 RNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIPAQTLGGVNSVISH 328
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 821595411 354 PAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:PRK06460 329 PATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRAL 372
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
21-400 |
1.18e-84 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 262.62 E-value: 1.18e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIH-VGSEPEQWSSMAvvPPISLSTTFKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKyCLAVASGLAA-TLT 98
Cdd:PRK07582 5 GTRSVHaGGPEAVPGEPVL--PGPVFAAPYHLSPGEPTGPDTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAAiTAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 99 ITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFAdlTKLEELKAGLKPnTKMVWIETPTNPTMKVVDIQACADIV 178
Cdd:PRK07582 82 LRALLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREA--PTAGMAEAALAG-ADLVLAETPSNPGLDVCDLAALAAAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 179 HkhNKDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMC 258
Cdd:PRK07582 159 H--AAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 259 NRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIkGKLEHASTFLSNLKLF 338
Cdd:PRK07582 237 HRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASRLV 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 821595411 339 ALAESLGGyeslaehpaimTHASVceEERKKLG--ISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK07582 316 VAATSFGG-----------VHTSA--DRRARWGdaVPEGFVRLSCGIEDTDDLVADLERALDAL 366
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
19-402 |
2.27e-84 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 263.92 E-value: 2.27e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 19 SFATDAIHVGSEPEQwSSMAVVPPISLSTTF----KQHGPGKHA----GFEYSRSGNPTRNCLEKAVAALDGAKYCLAVA 90
Cdd:PRK07812 13 SFETKQIHAGQTPDP-ATNARALPIYQTTSYtfddTDHAAALFGlaepGNIYTRIMNPTQDVVEQRIAALEGGVAALLLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 91 SGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISF-ADLTKLEELKAGLKPNTKMVWIETPTNPTMKV 168
Cdd:PRK07812 92 SGQAAeTFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFvEDPDDLDAWRAAVRPNTKAFFAETISNPQIDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 169 VDIQACADIVHKHNKDTIVvvDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLI--------SLSR-------D 233
Cdd:PRK07812 172 LDIPGVAEVAHEAGVPLIV--DNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIvdggtfdwTQGRfpgfttpD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 234 DLYERLKF---------------LQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLP 298
Cdd:PRK07812 250 PSYHGVVFaelgppayalkarvqLLRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLP 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 299 SHPQHELTKRQC-TGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLI 377
Cdd:PRK07812 330 SSPWYERAKRLApKGTGAVLSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLV 409
|
410 420
....*....|....*....|....*
gi 821595411 378 RLSVGLEDEEDIIADLDQALGAAHP 402
Cdd:PRK07812 410 RLAVGIEGIDDILADLEAGFAAAKA 434
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
60-398 |
2.70e-83 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 260.05 E-value: 2.70e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 60 FEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAATLT-ITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFAD 138
Cdd:PRK07810 62 FVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVFTaLGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVD 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 139 LTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMN 218
Cdd:PRK07810 142 GEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAG--AKVVLDNVFATPLLQRGLPLGADVVVYSGTKHID 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 219 GHSDVVMGLISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLP 298
Cdd:PRK07810 220 GQGRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLP 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 299 SHPQHELTKRQCTGCPGMITFYIK-----GKlEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGIS 373
Cdd:PRK07810 300 SHPQYDLAKRQMSGGGTVVTFELDapedaAK-KRAFEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLG 378
|
330 340
....*....|....*....|....*
gi 821595411 374 DTLIRLSVGLEDEEDIIADLDQALG 398
Cdd:PRK07810 379 DGVVRLSVGLEDTDDLIADLDRALG 403
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
20-400 |
5.09e-81 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 255.43 E-value: 5.09e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 20 FATDAIHVGSEPEQWSSMAVVPpISLSTTF----KQHGPG----KHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVAS 91
Cdd:PRK08134 9 FDTLALHAGAAPDPATGARAVP-IHLTTSFvfrdSDHAAAlfnlERAGHVYSRISNPTVAVLEERVAALEGGVGAIATAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 92 GLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVD 170
Cdd:PRK08134 88 GQAAlHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 171 IQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLI---------------SLSRD-D 234
Cdd:PRK08134 168 IPTVAAIAHEAG--VPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLvdggrfdweasgkfpELTEPyA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 235 LYERLKFLQNS----------------LGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLP 298
Cdd:PRK08134 246 GFHGMVFAEEStvaafllrarreglrdFGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 299 SHPQHELTKRQC-TGCPGMITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLI 377
Cdd:PRK08134 326 SHPDHALAKRLLpRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTI 405
|
410 420
....*....|....*....|...
gi 821595411 378 RLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK08134 406 RLSIGLEDADDLIDDLKRALKAA 428
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
1-400 |
1.53e-78 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 247.80 E-value: 1.53e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 1 MSSEMQNDSSAGFlpiyksfATDAIHVGSEPEQWSSMaVVPPISLSTTF----KQHGPGKHAGFEYSRSGNPTRNCLEKA 76
Cdd:PRK05967 1 MAKKQLKTEKAGI-------NTRLAHDGNDPGDYHGF-VNPPVVHASTVlfpdAETMATRGQKYTYGTRGTPTTDALCKA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 77 VAALDGAKYCLAVASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKM 155
Cdd:PRK05967 73 IDALEGSAGTILVPSGLAAvTVPFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 156 VWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISlSRDDL 235
Cdd:PRK05967 153 VHTEAPGSNTFEMQDIPAIAEAAHRHG--AIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVS-ANEKC 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 236 YERLKFLQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPG 315
Cdd:PRK05967 230 WPQLLEAHGTLGLCAGPDDTYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 316 MITFYIKGKLEH----ASTFLSNLKLFALAESLGGYESLAehpaimTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIA 391
Cdd:PRK05967 310 IFSFVLAAGPEKgkakAHAFLDALEIFGLGYSWGGYESLA------LHVKLGDRTVAKAPYAGPVIRLQIGLEDVPDLKA 383
|
....*....
gi 821595411 392 DLDQALGAA 400
Cdd:PRK05967 384 DLERGFAAA 392
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
55-400 |
2.03e-78 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 247.29 E-value: 2.03e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 55 GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVAsEVGLD 133
Cdd:PRK05939 34 GKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAiAAVFLTLLRAGDHLVSSQFLFGNTNSLFGTLR-GLGVE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 134 ISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSA 213
Cdd:PRK05939 113 VTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERG--LLYVVDNTMTSPWLFRPKDVGASLVINSL 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 214 TKYMNGHSDVV------MGLISLSR-DDLYE---------------RLKFLQNsLGAVPSPFDCYMCNRGLKTLHLRMKQ 271
Cdd:PRK05939 191 SKYIAGHGNALggavtdTGLFDWSAyPNIFPayrkgdpqqwgltqiRKKGLRD-MGATLSSEAAHRIAIGAETLALRVDR 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 272 HFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKgklEHAST--FLSNLKLFALAESLGGYES 349
Cdd:PRK05939 270 SCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELA---DGIDCfdFLNRLKLVIKATHLGDTRT 346
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 821595411 350 LAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK05939 347 LVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
24-400 |
5.22e-75 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 238.44 E-value: 5.22e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 24 AIHVGSEPEQWSSMAVVPPI---SLsTTFKQHGP------GKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLA 94
Cdd:PRK05968 11 AALITAHDEGNAFDAVVPPIfqtSL-FTFDSYDEmedvyaGEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 95 A-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLkPNTKMVWIETPTNPTMKVVDIQA 173
Cdd:PRK05968 90 AiSSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESPTSWVFELQDVAA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 174 CADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRdDLYERLKFLQNS-LGAVPSP 252
Cdd:PRK05968 169 LAALAKRHG--VVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSK-EHIARINAEAYPyLGAKLSP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 253 FDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELtkrqcTGCPGMITFYIKGKLeHASTFL 332
Cdd:PRK05968 246 FEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSFIFREGI-DVRAFA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 821595411 333 SNLKLFALAESLGGYESL-------AEHPAIMTHASvceeerkKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK05968 320 DALKLFRLGVSWGGHESLvvpaevvLQQKAQPNSAA-------RFGVSPRSVRLHVGLEGTEALWADLEQALAAA 387
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
22-400 |
2.68e-74 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 236.31 E-value: 2.68e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 22 TDAIHVGSEPEQwSSMAVVPPISLSTT--FKQHGPGKHAGFE--YSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-T 96
Cdd:TIGR01324 1 TRLIHSGRQPRF-SQGSVNPPLQRASTvlFDSHAAQRRAKGEltYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAvT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 97 LTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVDIQACAD 176
Cdd:TIGR01324 80 NSILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 177 IVHkhNKDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISlSRDDLYERLKFLQNSLGAVPSPFDCY 256
Cdd:TIGR01324 160 AAR--NPGIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVV-ANARTWDQLREHSYLMGQMVDADDAY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 257 MCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKG-KLEHASTFLSNL 335
Cdd:TIGR01324 237 TTLRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRlTQKQVHAFLDHL 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 821595411 336 KLFALAESLGGYESLA--EHPAIMTHASVceeerkKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:TIGR01324 317 QLFGLGYSWGGYESLAlcNQPELGHRPNI------KRNLEGPLIRVHIGLENVDDLKADLKAGFEAI 377
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
18-400 |
1.84e-73 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 234.62 E-value: 1.84e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 18 KSFATDAIHVGSE-PEQWSSMavVPPISLSTT--------FKQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLA 88
Cdd:PRK07050 8 RALQTRIVQPDDQiPPGFRSF--VTPVARASTvvfpdlatMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 89 VASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMK 167
Cdd:PRK07050 86 QPSGLAAiSLVYFGLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTME 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 168 VVDIQACADIVHKHNkdTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNSLG 247
Cdd:PRK07050 166 VPDVPAITAAARARG--VVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 248 AVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKL-- 325
Cdd:PRK07050 244 IGVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDERYsp 323
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 821595411 326 EHASTFLSNLKLFALAESLGGYESLA--EHPAIMTHAsvceeerkKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 400
Cdd:PRK07050 324 AQVDAFVEALELFAIGWSWGGACSLAmpYDVASMRTA--------KWPHRGTLVRLYIGLEDEADLIADLEQALEAA 392
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
19-399 |
7.78e-71 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 228.99 E-value: 7.78e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 19 SFATDAIHVGsEPEQWSSMAVVPPISLSTTF--------KQHGPGKHAGFEYSRSGNPTRNCLEKAVAALDGAKYCLAVA 90
Cdd:PRK05613 13 GFETRSIHAG-QSVDSDTSARNLPIYQTTSYvfdsaehaKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 91 SGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFA-DLTKLEELKAGLKPNTKMVWIETPTNPTMKV 168
Cdd:PRK05613 92 SGQAAeTAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 169 VDIQACADIVHKHNKDTIVvvDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLI--------SLSR-------- 232
Cdd:PRK05613 172 LDIPAVAEVAHRNQVPLIV--DNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLidggkfdwTVERdgkpvfpy 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 233 ----DDLYERLKF---------------LQNSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVI 293
Cdd:PRK05613 250 fvtpDPAYHGLKYadlgapafglkaragLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVN 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 294 FPGLPSHPQHELTKRQCTGCPG-MITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGI 372
Cdd:PRK05613 330 FAGLKDSPWYATKEKLGLKYTGsVLSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGI 409
|
410 420
....*....|....*....|....*..
gi 821595411 373 SDTLIRLSVGLEDEEDIIADLDQALGA 399
Cdd:PRK05613 410 TQATVRLSVGIEDIDDIIADLEGGFAA 436
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
21-397 |
4.69e-70 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 225.77 E-value: 4.69e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 21 ATDAIHVGSEpEQWSSMAVVPPISLSTTF-------KQHGPGKHAGFE--YSRSGNPTRNCLEKAVAALDGAKYCLAVAS 91
Cdd:PRK09028 6 ATKIVSAGRD-KKWTKGVINPPVFRASTVvfdtvaeMRHAAKNRANGEmfYGRRGTPTHFAFQAAIVELEGGAGTALYPS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 92 GLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMKVVD 170
Cdd:PRK09028 85 GAAAiSNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 171 IQACADIVHKHnkDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGlISLSRDDLYERLKFLQNSLGAVP 250
Cdd:PRK09028 165 VPTLSRIAHEH--DIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLG-TATANEKHWDQLREHSYLMGQCT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 251 SPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIK-GKLEHAS 329
Cdd:PRK09028 242 SPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDPKAVT 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 821595411 330 TFLSNLKLFALAESLGGYESLaehpaIMTHASVCE-EERKKLGISDTLIRLSVGLEDEEDIIADLDQAL 397
Cdd:PRK09028 322 ALVEGMQHFKMGFSWGGFESL-----ILGVFGINKlRTATNWDFSKPLIRLHIGLEDVDDLIADLEAGF 385
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
18-394 |
8.45e-67 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 217.26 E-value: 8.45e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 18 KSFATDAIHVGSEPeQWSSMAVVPPI----SL---STTFKQHGPGKHAGFE--YSRSGNPTRNCLEKAVAALDGAKYCLA 88
Cdd:PRK08114 4 KKLDTQLVNAGRSK-KYTQGSVNSVIqrasSLvfdSVEAKKHATRNRANGElfYGRRGTLTHFSLQEAMCELEGGAGCAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 89 VASGLAA-TLTITHLFKSGDGILCMNDVYGGTNRYFRKVASEVGLDISFADLTKLEELKAGLKPNTKMVWIETPTNPTMK 167
Cdd:PRK08114 83 YPCGAAAvANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITME 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 168 VVDIQACADIVHKHNKDTIVVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGlISLSRDDLYERLKflQNS-- 245
Cdd:PRK08114 163 VHDVPAIVAAVRSVNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIG-TAVANARCWEQLR--ENSyl 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 246 LGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCTGCPGMITFYIKGKL 325
Cdd:PRK08114 240 MGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKKL 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 821595411 326 EHA--STFLSNLKLFALAESLGGYESL-----AEHPAIMTHASvceeERKKLGisdTLIRLSVGLEDEEDIIADLD 394
Cdd:PRK08114 320 TDEqlANYLDNFSLFSMAYSWGGFESLilanqPEEIAAIRPAG----EVDFTG---TLIRLHIGLEDVDDLIADLA 388
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
40-397 |
4.71e-62 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 206.06 E-value: 4.71e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 40 VPPISLSTTFKQHGPGKHA--------GFEYSRSGNPTRNCLEKAVAALDGAKYCLAVASGLAA-TLTITHLFKSGDGIL 110
Cdd:PRK06702 25 VLPLYQSTTYKYDTSDDLAalfnleaeGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAiMLAVLNICSSGDHLL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 111 CMNDVYGGTNRYFRKVASEVGLDISF--ADLTKlEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKhnKDTIVV 188
Cdd:PRK06702 105 CSSTVYGGTFNLFGVSLRKLGIDVTFfnPNLTA-DEIVALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKE--LEVPFI 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 189 VDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLIS---------------LSRDDLYERLKFLQN--------- 244
Cdd:PRK06702 182 VDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelVEPDPSYHGVSYVQNfgaaayivk 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 245 -------SLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEADPRVDRVIFPGLPSHPQHELTKRQCT-GCPGM 316
Cdd:PRK06702 262 arvqllrDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNENYSLAQKYLKkGASGV 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 317 ITFYIKGKLEHASTFLSNLKLFALAESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQA 396
Cdd:PRK06702 342 LTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLSVGIEDVSDIIADLEAA 421
|
.
gi 821595411 397 L 397
Cdd:PRK06702 422 L 422
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
32-382 |
6.61e-51 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 176.49 E-value: 6.61e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 32 EQWSSMAVVPPISLSTTFK-QHGPgKHAGFEYSRSGNPTRNCLEKAVAALDG--AKYClaVASGLAA-TLTITHLFKSGD 107
Cdd:PLN02242 40 EASATFTVMEPDTMRRMFSgELGP-DRDFYIYSRHFNPTVLNLGRQMAALEGteAAYC--TASGMSAiSSVLLQLCSSGG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 108 GILCMNDVYGGTNRYFRKVASEV-GLDISFADLTKLEELKAGLKPN-TKMVWIETPTNPTMKVVDIQACADIVHkhNKDT 185
Cdd:PLN02242 117 HVVASNTLYGGTHALLAHFLPRKcNITTTFVDITDLEAVKKAVVPGkTKVLYFESISNPTLTVADIPELARIAH--EKGV 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 186 IVVVDNTFmSAYFQRPLALGADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQNS---LGAVPSPFDCYMCNRGL 262
Cdd:PLN02242 195 TVVVDNTF-APMVLSPARLGADVVVHSISKFISGGADIIAGAVCGPAELVNSMMDLHHGAlmlLGPTMNPKVAFELSERL 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 263 KTLHLRMKQHFKNALAAAQFLEADPRvdRVIFPGLPSHPQHELTKRQ---CTGCPGMITFYIKGKlEHASTF---LSNLK 336
Cdd:PLN02242 274 PHLSLRMKEHCRRAMEYAKRMKELGL--KVIYPGLEDHPQHALLKSMankGYGFGGLLCLDMDTE-ERANRLmryLQNST 350
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 821595411 337 LFAL-AESLGGYESLAEHPAIMTHASVCEEERKKLGISDTLIRLSVG 382
Cdd:PLN02242 351 QFGFmAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVG 397
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
73-219 |
2.78e-11 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 61.63 E-value: 2.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 73 LEKAVAAL--DGAKYCLAVASGLAATLTITH-LFKSGDGILCMNDVYGGtnRYFRKVASeVGLDIS----------FADL 139
Cdd:cd01494 5 LEEKLARLlqPGNDKAVFVPSGTGANEAALLaLLGPGDEVIVDANGHGS--RYWVAAEL-AGAKPVpvpvddagygGLDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 140 TKLEELKAglKPNTKMVWIETPTNPTMKVVDIQACADIVHKHnkDTIVVVDNTF----MSAYFQRPLALGADICMYSATK 215
Cdd:cd01494 82 AILEELKA--KPNVALIVITPNTTSGGVLVPLKEIRKIAKEY--GILLLVDAASaggaSPAPGVLIPEGGADVVTFSLHK 157
|
....
gi 821595411 216 YMNG 219
Cdd:cd01494 158 NLGG 161
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
73-310 |
5.01e-08 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 54.27 E-value: 5.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 73 LEKAVAALDGAKYCLAV-ASGLAAT--------LTITHLFKSGDGILCMNDVYGGTNRYFRK---VASEVGLDISFADLT 140
Cdd:cd00609 41 LREAIAEWLGRRGGVDVpPEEIVVTngaqealsLLLRALLNPGDEVLVPDPTYPGYEAAARLagaEVVPVPLDEEGGFLL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 141 KLEELKAGLKPNTKMVWIETPTNPTMKVVD---IQACADIVHKHnkDTIVVVDNT---FMSAYFQRPLALGAD-----IC 209
Cdd:cd00609 121 DLELLEAAKTPKTKLLYLNNPNNPTGAVLSeeeLEELAELAKKH--GILIISDEAyaeLVYDGEPPPALALLDayervIV 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 210 MYSATKYMNghsdvVMGL----ISLSRDDLYERLKFLQNSLGAVPSPFDCYMCNRGLKTLH---LRMKQHFK-NALAAAQ 281
Cdd:cd00609 199 LRSFSKTFG-----LPGLrigyLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAALDDGEehlEELRERYRrRRDALLE 273
|
250 260 270
....*....|....*....|....*....|....*.
gi 821595411 282 FLEADPRVDRV-------IFPGLPSHPQHELTKRQC 310
Cdd:cd00609 274 ALKELGPLVVVkpsggffLWLDLPEGDDEEFLERLL 309
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
142-209 |
7.26e-07 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 50.87 E-value: 7.26e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 821595411 142 LEELKAGLKPNTKMVWIETPT----NPTMKVVDIQACADIVHKHNKDTIVVVDNtfmsAY--F---QRPLALGADIC 209
Cdd:COG4100 147 LEAIKKAINEKTKMVLIQRSRgyswRPSLTIEEIGEIIKFVKSINPDVICFVDN----CYgeFvetREPTEVGADLM 219
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
142-194 |
7.70e-05 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 44.35 E-value: 7.70e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 821595411 142 LEELKAGLKPNTKMVWIETPTNPTMKVVDIQACADIVHKHNKDTIVVVDNTFM 194
Cdd:COG0079 126 LDALLAAITERTDLVFLCNPNNPTGTLLPREELEALLEALPADGLVVVDEAYA 178
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
88-239 |
1.01e-04 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 44.47 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 88 AVASGLAA------TLTITHLFKSGDGILCMNDVYggT--------NRYFRKV----ASEV-GLDISFADLTKLEElkag 148
Cdd:PRK09275 166 AVEGGTAAmcyifdSLKENGLLKAGDKIALMTPIF--TpyleipelPRYDLEVvhinADEEnEWQYPDSELEKLRD---- 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 149 lkPNTKMVWIETPTNPT-MKVVD--IQACADIVHKHNKDTIVVVDN---TFMSAYfqrpLALGAD-----ICMYSATKYM 217
Cdd:PRK09275 240 --PSIKALFLVNPSNPPsVAMSDesLEKIADIVNEKRPDLMIITDDvygTFVDDF----RSLFAVlpyntILVYSFSKYF 313
|
170 180
....*....|....*....|..
gi 821595411 218 nGHSDVVMGLISLSRDDLYERL 239
Cdd:PRK09275 314 -GATGWRLGVIALHEDNVFDKL 334
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
142-191 |
3.24e-04 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 42.42 E-value: 3.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 821595411 142 LEELKAGLKPNTKMVWIETPTNPTMKVV---DIQACADIVHKHnkDTIVVVDN 191
Cdd:COG0436 153 PEALEAAITPRTKAIVLNSPNNPTGAVYsreELEALAELAREH--DLLVISDE 203
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
74-307 |
3.96e-04 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 42.29 E-value: 3.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 74 EKAVAALDGAKYCLAVASGLAATltithlfkSGDGILCMNDVYGGTNRYFRKVASEV------GLDISFADLTKLEELka 147
Cdd:pfam00155 63 EAAVVFGSGAGANIEALIFLLAN--------PGDAILVPAPTYASYIRIARLAGGEVvryplyDSNDFHLDFDALEAA-- 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 148 gLKPNTKMVWIETPTNPTMKVV---DIQACADIVHKHNkdTIVVVDNTFM-------SAYFQRPLALGAD--ICMYSATK 215
Cdd:pfam00155 133 -LKEKPKVVLHTSPHNPTGTVAtleELEKLLDLAKEHN--ILLLVDEAYAgfvfgspDAVATRALLAEGPnlLVVGSFSK 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 216 ----------YMNGHSDVVMGLISLSRDDLYERlkFLQNSLGAVPSPFDCYM-CNRGLKTLHLRMKQHFKNALAAAQFLE 284
Cdd:pfam00155 210 afglagwrvgYILGNAAVISQLRKLARPFYSST--HLQAAAAAALSDPLLVAsELEEMRQRIKERRDYLRDGLQAAGLSV 287
|
250 260
....*....|....*....|...
gi 821595411 285 ADPRVDRVIFPGLPSHPQHELTK 307
Cdd:pfam00155 288 LPSQAGFFLLTGLDPETAKELAQ 310
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
129-208 |
5.42e-03 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 38.58 E-value: 5.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 129 EVGLDisfADLTKLEELKAGLKPNTKMVWIETPtNPTMKVVDIQACADIVHKHNKDTIVVVDNTFMSAYfQRPLALGADI 208
Cdd:PRK00451 184 EVPYE---DGVTDLEALEAAVDDDTAAVVVQYP-NFFGVIEDLEEIAEIAHAGGALFIVGVDPVSLGLL-KPPGEYGADI 258
|
|
| hisC |
TIGR01141 |
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ... |
99-190 |
7.19e-03 |
|
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]
Pssm-ID: 273467 Cd Length: 350 Bit Score: 38.40 E-value: 7.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 821595411 99 ITHLF-KSGDGILCMNDVYGgtnrYFRKVASEVGLDISFADLTK-----LEELKAGLKPNTKMVWIETPTNPTMKVV--- 169
Cdd:TIGR01141 88 LIRAFlEPGDAVLVPPPTYS----MYEISAKIHGAEVVKVPLDEdgqldLEDILVAIDDKPKLVFLCSPNNPTGNLFsrg 163
|
90 100
....*....|....*....|.
gi 821595411 170 DIQACADIVhkhNKDTIVVVD 190
Cdd:TIGR01141 164 DIEAVLERT---PGDALVVVD 181
|
|
| |
