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Conserved domains on  [gi|46359855|ref|NP_997001|]
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general transcription factor IIH subunit 5 [Homo sapiens]

Protein Classification

general transcription factor IIH subunit TFB5 family protein( domain architecture ID 10533723)

general transcription factor IIH subunit TFB5 family protein is a component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tfb5 pfam06331
Transcription factor TFIIH complex subunit Tfb5; This family is a component of the general ...
 1-69 7.67e-26

Transcription factor TFIIH complex subunit Tfb5; This family is a component of the general transcription and DNA repair factor IIH. TFB5 has been shown to be required for efficient recruitment of TFIIH to a promoter.


:

Pssm-ID: 428891  Cd Length: 67  Bit Score: 89.84  E-value: 7.67e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46359855    1 MVNVLKGVLIECDPAMKQFLLYLDESNalGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLT 69
Cdd:pfam06331  1 MVRAIKGVLVECDPSIKQIILHLDESL--GHKFIIEDLDDTHLFIKPDKVEMLKRKLEELLEENTYEPE 67
 
Name Accession Description Interval E-value
Tfb5 pfam06331
Transcription factor TFIIH complex subunit Tfb5; This family is a component of the general ...
 1-69 7.67e-26

Transcription factor TFIIH complex subunit Tfb5; This family is a component of the general transcription and DNA repair factor IIH. TFB5 has been shown to be required for efficient recruitment of TFIIH to a promoter.


Pssm-ID: 428891  Cd Length: 67  Bit Score: 89.84  E-value: 7.67e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46359855    1 MVNVLKGVLIECDPAMKQFLLYLDESNalGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLT 69
Cdd:pfam06331  1 MVRAIKGVLVECDPSIKQIILHLDESL--GHKFIIEDLDDTHLFIKPDKVEMLKRKLEELLEENTYEPE 67
 
Name Accession Description Interval E-value
Tfb5 pfam06331
Transcription factor TFIIH complex subunit Tfb5; This family is a component of the general ...
 1-69 7.67e-26

Transcription factor TFIIH complex subunit Tfb5; This family is a component of the general transcription and DNA repair factor IIH. TFB5 has been shown to be required for efficient recruitment of TFIIH to a promoter.


Pssm-ID: 428891  Cd Length: 67  Bit Score: 89.84  E-value: 7.67e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46359855    1 MVNVLKGVLIECDPAMKQFLLYLDESNalGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLT 69
Cdd:pfam06331  1 MVRAIKGVLVECDPSIKQIILHLDESL--GHKFIIEDLDDTHLFIKPDKVEMLKRKLEELLEENTYEPE 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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