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Conserved domains on  [gi|42741684|ref|NP_976225|]
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zinc finger Ran-binding domain-containing protein 2 isoform 1 [Homo sapiens]

Protein Classification

zinc finger Ran-binding domain-containing protein( domain architecture ID 10650940)

zinc finger Ran-binding domain-containing protein; similar to human zinc finger Ran-binding domain-containing protein 2 (ZRANB2) which is a splice factor required for alternative splicing of TRA2B/SFRS10 transcripts and whose zinc finger domains bind single-stranded RNA, and to the zinc finger domain of human TAK1-binding protein 2 (TAB2) which binds Lys 63-linked polyubiquitin chains

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
67-91 1.48e-05

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


:

Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 41.15  E-value: 1.48e-05
                           10        20
                   ....*....|....*....|....*
gi 42741684     67 NDWQCKTCSNVNWARRSECNMCNTP 91
Cdd:smart00547   1 GDWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
11-35 3.37e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


:

Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 37.30  E-value: 3.37e-04
                           10        20
                   ....*....|....*....|....*
gi 42741684     11 GDWICPdkKCGNVNFARRTSCNRCG 35
Cdd:smart00547   1 GDWECP--ACTFLNFASRSKCFACG 23
 
Name Accession Description Interval E-value
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
67-91 1.48e-05

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 41.15  E-value: 1.48e-05
                           10        20
                   ....*....|....*....|....*
gi 42741684     67 NDWQCKTCSNVNWARRSECNMCNTP 91
Cdd:smart00547   1 GDWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
11-35 3.37e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 37.30  E-value: 3.37e-04
                           10        20
                   ....*....|....*....|....*
gi 42741684     11 GDWICPdkKCGNVNFARRTSCNRCG 35
Cdd:smart00547   1 GDWECP--ACTFLNFASRSKCFACG 23
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
65-93 4.72e-04

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 36.95  E-value: 4.72e-04
                          10        20
                  ....*....|....*....|....*....
gi 42741684    65 SANDWQCKTCSNVNWARRSECNMCNTPKY 93
Cdd:pfam00641   1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
9-38 1.46e-03

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 35.79  E-value: 1.46e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 42741684     9 SDGDWICPdkKCGNVNFARRTSCNRCGREK 38
Cdd:pfam00641   1 REGDWDCS--KCLVQNFATSTKCVACQAPK 28
 
Name Accession Description Interval E-value
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
67-91 1.48e-05

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 41.15  E-value: 1.48e-05
                           10        20
                   ....*....|....*....|....*
gi 42741684     67 NDWQCKTCSNVNWARRSECNMCNTP 91
Cdd:smart00547   1 GDWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
11-35 3.37e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 37.30  E-value: 3.37e-04
                           10        20
                   ....*....|....*....|....*
gi 42741684     11 GDWICPdkKCGNVNFARRTSCNRCG 35
Cdd:smart00547   1 GDWECP--ACTFLNFASRSKCFACG 23
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
65-93 4.72e-04

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 36.95  E-value: 4.72e-04
                          10        20
                  ....*....|....*....|....*....
gi 42741684    65 SANDWQCKTCSNVNWARRSECNMCNTPKY 93
Cdd:pfam00641   1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
9-38 1.46e-03

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 35.79  E-value: 1.46e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 42741684     9 SDGDWICPdkKCGNVNFARRTSCNRCGREK 38
Cdd:pfam00641   1 REGDWDCS--KCLVQNFATSTKCVACQAPK 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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