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Conserved domains on  [gi|41872443|ref|NP_955400|]
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short transient receptor potential channel 4-associated protein isoform b [Homo sapiens]

Protein Classification

short transient receptor potential channel 4-associated protein( domain architecture ID 10575640)

short transient receptor potential channel 4-associated protein is a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3689 pfam12463
Protein of unknown function (DUF3689); This family of proteins is found in eukaryotes. ...
 399-705 9.07e-167

Protein of unknown function (DUF3689); This family of proteins is found in eukaryotes. Proteins in this family are typically between 399 and 797 amino acids in length.


:

Pssm-ID: 463595  Cd Length: 311  Bit Score: 483.87  E-value: 9.07e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   399 VHRMIAEFKLIPGLNNLFDKLIWRKHS---ASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNE 475
Cdd:pfam12463   1 VQKRLAELGLVPGLNNLFDKFIWKPDSprlSSDHPLHGHNQNCDCSPDTTLKIQFLRLVHSFCDHSSYKYLLLSSQELNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   476 LSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEH 555
Cdd:pfam12463  81 LKQISSKANSLELSAVQNVDRSLACDGKKGLLSKIMHVLKKEPTDSSFRFWLARAVESFLRGATSYADQAFLLRRGLLQH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   556 ILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQVD 635
Cdd:pfam12463 161 ILYELLSSECKSREVLQSSFDLLGELIKFNVEAFKRFDKLLNTDEKFQKFLNVVNLNLVDSNMFIRSIMLTLDHFMSQSD 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   636 MKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQ 705
Cdd:pfam12463 241 QKVAYVLEECRLLSYFTDPNRRMWYLARLMTIISVDTLTQENVSCLNTALVILMFAHRKGRLASYLQALR 310
 
Name Accession Description Interval E-value
DUF3689 pfam12463
Protein of unknown function (DUF3689); This family of proteins is found in eukaryotes. ...
 399-705 9.07e-167

Protein of unknown function (DUF3689); This family of proteins is found in eukaryotes. Proteins in this family are typically between 399 and 797 amino acids in length.


Pssm-ID: 463595  Cd Length: 311  Bit Score: 483.87  E-value: 9.07e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   399 VHRMIAEFKLIPGLNNLFDKLIWRKHS---ASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNE 475
Cdd:pfam12463   1 VQKRLAELGLVPGLNNLFDKFIWKPDSprlSSDHPLHGHNQNCDCSPDTTLKIQFLRLVHSFCDHSSYKYLLLSSQELNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   476 LSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEH 555
Cdd:pfam12463  81 LKQISSKANSLELSAVQNVDRSLACDGKKGLLSKIMHVLKKEPTDSSFRFWLARAVESFLRGATSYADQAFLLRRGLLQH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   556 ILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQVD 635
Cdd:pfam12463 161 ILYELLSSECKSREVLQSSFDLLGELIKFNVEAFKRFDKLLNTDEKFQKFLNVVNLNLVDSNMFIRSIMLTLDHFMSQSD 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   636 MKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQ 705
Cdd:pfam12463 241 QKVAYVLEECRLLSYFTDPNRRMWYLARLMTIISVDTLTQENVSCLNTALVILMFAHRKGRLASYLQALR 310
 
Name Accession Description Interval E-value
DUF3689 pfam12463
Protein of unknown function (DUF3689); This family of proteins is found in eukaryotes. ...
 399-705 9.07e-167

Protein of unknown function (DUF3689); This family of proteins is found in eukaryotes. Proteins in this family are typically between 399 and 797 amino acids in length.


Pssm-ID: 463595  Cd Length: 311  Bit Score: 483.87  E-value: 9.07e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   399 VHRMIAEFKLIPGLNNLFDKLIWRKHS---ASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNE 475
Cdd:pfam12463   1 VQKRLAELGLVPGLNNLFDKFIWKPDSprlSSDHPLHGHNQNCDCSPDTTLKIQFLRLVHSFCDHSSYKYLLLSSQELNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   476 LSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEH 555
Cdd:pfam12463  81 LKQISSKANSLELSAVQNVDRSLACDGKKGLLSKIMHVLKKEPTDSSFRFWLARAVESFLRGATSYADQAFLLRRGLLQH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   556 ILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQVD 635
Cdd:pfam12463 161 ILYELLSSECKSREVLQSSFDLLGELIKFNVEAFKRFDKLLNTDEKFQKFLNVVNLNLVDSNMFIRSIMLTLDHFMSQSD 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872443   636 MKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQ 705
Cdd:pfam12463 241 QKVAYVLEECRLLSYFTDPNRRMWYLARLMTIISVDTLTQENVSCLNTALVILMFAHRKGRLASYLQALR 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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