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Conserved domains on  [gi|98986321|ref|NP_861454|]
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gliomedin isoform 1 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
304-544 3.72e-106

Olfactomedin-like domain;


:

Pssm-ID: 460482  Cd Length: 246  Bit Score: 318.32  E-value: 3.72e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   304 ITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTF-IHLPYYFHGCGHVVYNNSLY 382
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTDRGTSGNTLREYASLDDFKNGSPSKkYKLPYPWQGTGHVVYNGSLY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   383 YHKGGSNTLVRFEFGQET-SQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQ 461
Cdd:pfam02191  81 YNKYNSRNIVKYDLTTRTvAARRVLPGAGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSKLDPETLEVEQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   462 HVNTTYPKSKAGNAFIARGILYVTD---TKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLM 538
Cdd:pfam02191 161 TWNTSYPKRSAGNAFMVCGVLYAVRsvnTRREEIFYAFDTYTGKEEAVSIPFPNRYGKISMLDYNPRDKKLYAWDDGYQV 240


                  ....*.
gi 98986321   539 LYPVQF 544
Cdd:pfam02191 241 TYPVTF 246
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 157-212 9.31e-14

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


:

Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 65.59  E-value: 9.31e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 98986321   157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQ 212
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-291 1.48e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.63  E-value: 1.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGElglQGNEGPPGQKGEKGDKGDvsndvllAGAKGDQG 236
Cdd:NF038329 126 GPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGE---AGPQGPAGKDGEAGAKGP-------AGEKGPQG 195

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 98986321  237 PPGPPGPPGPpgppgppgsRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEK 291
Cdd:NF038329 196 PRGETGPAGE---------QGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDP 241
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
304-544 3.72e-106

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 318.32  E-value: 3.72e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   304 ITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTF-IHLPYYFHGCGHVVYNNSLY 382
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTDRGTSGNTLREYASLDDFKNGSPSKkYKLPYPWQGTGHVVYNGSLY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   383 YHKGGSNTLVRFEFGQET-SQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQ 461
Cdd:pfam02191  81 YNKYNSRNIVKYDLTTRTvAARRVLPGAGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSKLDPETLEVEQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   462 HVNTTYPKSKAGNAFIARGILYVTD---TKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLM 538
Cdd:pfam02191 161 TWNTSYPKRSAGNAFMVCGVLYAVRsvnTRREEIFYAFDTYTGKEEAVSIPFPNRYGKISMLDYNPRDKKLYAWDDGYQV 240


                  ....*.
gi 98986321   539 LYPVQF 544
Cdd:pfam02191 241 TYPVTF 246
OLF smart00284
Olfactomedin-like domains;
304-544 5.77e-43

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 153.83  E-value: 5.77e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321    304 ITSIGNPVqVLKVTET--FGTWIRESANKS--DDRIWVTEHFSGIM--VKEFKDQPSLLNGSYTFIH-LPYYFHGCGHVV 376
Cdd:smart00284   3 LAGISKPV-TLQTSWKgkSGAWMKDPLWNTtkKSLYWYMPLNTRVLrsVREYSSMSDFQMGKNPTDHpLPHAGQGTGVVV 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321    377 YNNSLYYHKGGSNTLVRFEFGQETSQTLK-LENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDER 455
Cdd:smart00284  82 YNGSLYFNKFNSHDICRFDLTTETYQKEPlLNGAGYNNRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVISKLNPA 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321    456 TFSVVQHVNTTYPKSKAGNAFIARGILYVTDT---KDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSW 532
Cdd:smart00284 162 TLTIENTWITTYNKRSASNAFMICGILYVTRSlgsKGEKVFYAYDTNTGKEGHLDIPFENMYEYISMLDYNPNDRKLYAW 241

                          250
                   ....*....|..
gi 98986321    533 EDGHLMLYPVQF 544
Cdd:smart00284 242 NNGHLVHYDIAL 253
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 157-212 9.31e-14

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 65.59  E-value: 9.31e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 98986321   157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQ 212
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-291 1.48e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.63  E-value: 1.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGElglQGNEGPPGQKGEKGDKGDvsndvllAGAKGDQG 236
Cdd:NF038329 126 GPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGE---AGPQGPAGKDGEAGAKGP-------AGEKGPQG 195

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 98986321  237 PPGPPGPPGPpgppgppgsRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEK 291
Cdd:NF038329 196 PRGETGPAGE---------QGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDP 241
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-234 5.89e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 5.89e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGdvsndvlLAGAKGD 234
Cdd:NF038329 245 GEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNG-------KDGLPGK 315
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-241 6.10e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 6.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVllAGAKGDQG 236
Cdd:NF038329 162 GPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG--DGQQGPDG 239


                 ....*
gi 98986321  237 PPGPP 241
Cdd:NF038329 240 DPGPT 244
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-270 5.14e-10

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 61.84  E-value: 5.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPG--QKGEKGDKGDVSNDVLlAGAKGD 234
Cdd:NF038329 177 GKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGdgQQGPDGDPGPTGEDGP-QGPDGP 255

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 98986321  235 QGPPGPPGPPGPPGPPGPPGSRRAKGPRQPSMFNGQ 270
Cdd:NF038329 256 AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQ 291
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 156-220 2.66e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.53  E-value: 2.66e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 98986321  156 NGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKG 220
Cdd:NF038329 274 DGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 175-238 3.19e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 49.52  E-value: 3.19e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 98986321  175 GKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDvsndvllAGAKGDQGPP 238
Cdd:NF038329 117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGP-------AGPQGEAGPQ 173
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
304-544 3.72e-106

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 318.32  E-value: 3.72e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   304 ITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTF-IHLPYYFHGCGHVVYNNSLY 382
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTDRGTSGNTLREYASLDDFKNGSPSKkYKLPYPWQGTGHVVYNGSLY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   383 YHKGGSNTLVRFEFGQET-SQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQ 461
Cdd:pfam02191  81 YNKYNSRNIVKYDLTTRTvAARRVLPGAGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSKLDPETLEVEQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321   462 HVNTTYPKSKAGNAFIARGILYVTD---TKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLM 538
Cdd:pfam02191 161 TWNTSYPKRSAGNAFMVCGVLYAVRsvnTRREEIFYAFDTYTGKEEAVSIPFPNRYGKISMLDYNPRDKKLYAWDDGYQV 240


                  ....*.
gi 98986321   539 LYPVQF 544
Cdd:pfam02191 241 TYPVTF 246
OLF smart00284
Olfactomedin-like domains;
304-544 5.77e-43

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 153.83  E-value: 5.77e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321    304 ITSIGNPVqVLKVTET--FGTWIRESANKS--DDRIWVTEHFSGIM--VKEFKDQPSLLNGSYTFIH-LPYYFHGCGHVV 376
Cdd:smart00284   3 LAGISKPV-TLQTSWKgkSGAWMKDPLWNTtkKSLYWYMPLNTRVLrsVREYSSMSDFQMGKNPTDHpLPHAGQGTGVVV 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321    377 YNNSLYYHKGGSNTLVRFEFGQETSQTLK-LENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDER 455
Cdd:smart00284  82 YNGSLYFNKFNSHDICRFDLTTETYQKEPlLNGAGYNNRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVISKLNPA 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321    456 TFSVVQHVNTTYPKSKAGNAFIARGILYVTDT---KDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSW 532
Cdd:smart00284 162 TLTIENTWITTYNKRSASNAFMICGILYVTRSlgsKGEKVFYAYDTNTGKEGHLDIPFENMYEYISMLDYNPNDRKLYAW 241

                          250
                   ....*....|..
gi 98986321    533 EDGHLMLYPVQF 544
Cdd:smart00284 242 NNGHLVHYDIAL 253
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 157-212 9.31e-14

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 65.59  E-value: 9.31e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 98986321   157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQ 212
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-291 1.48e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.63  E-value: 1.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGElglQGNEGPPGQKGEKGDKGDvsndvllAGAKGDQG 236
Cdd:NF038329 126 GPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGE---AGPQGPAGKDGEAGAKGP-------AGEKGPQG 195

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 98986321  237 PPGPPGPPGPpgppgppgsRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEK 291
Cdd:NF038329 196 PRGETGPAGE---------QGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDP 241
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-234 5.89e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 5.89e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGdvsndvlLAGAKGD 234
Cdd:NF038329 245 GEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNG-------KDGLPGK 315
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-241 6.10e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 6.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVllAGAKGDQG 236
Cdd:NF038329 162 GPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG--DGQQGPDG 239


                 ....*
gi 98986321  237 PPGPP 241
Cdd:NF038329 240 DPGPT 244
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 157-270 5.14e-10

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 61.84  E-value: 5.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986321  157 GLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPG--QKGEKGDKGDVSNDVLlAGAKGD 234
Cdd:NF038329 177 GKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGdgQQGPDGDPGPTGEDGP-QGPDGP 255

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 98986321  235 QGPPGPPGPPGPPGPPGPPGSRRAKGPRQPSMFNGQ 270
Cdd:NF038329 256 AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQ 291
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 156-220 2.66e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.53  E-value: 2.66e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 98986321  156 NGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKG 220
Cdd:NF038329 274 DGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 163-215 1.63e-08

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 50.96  E-value: 1.63e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 98986321   163 GPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGdhgelglqgnegPPGQKGE 215
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPG------------PPGPPGP 41
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 175-238 3.19e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 49.52  E-value: 3.19e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 98986321  175 GKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDvsndvllAGAKGDQGPP 238
Cdd:NF038329 117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGP-------AGPQGEAGPQ 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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