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Conserved domains on  [gi|30519919|ref|NP_848717|]
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DNA-directed RNA polymerase II subunit GRINL1A isoform 1 [Mus musculus]

Protein Classification

GCOM2 domain-containing protein( domain architecture ID 10633975)

GCOM2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GCOM2 pfam15328
Putative GRINL1B complex locus protein 2; This protein family is named Putative GRINL1B ...
 37-239 2.10e-70

Putative GRINL1B complex locus protein 2; This protein family is named Putative GRINL1B complex locus protein 2. GRINL1B is short for: glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B. The name indicates what sort of receptor it is thought to be, a ligand gated ion channel specific to the neurotransmitter Glutamate. This family of proteins is found in eukaryotes. Proteins in this family are typically between 325 and 463 amino acids in length. The protein is thought to be the product of a pseudogene with a role in helping assemble a gene transcription unit.


:

Pssm-ID: 464649  Cd Length: 214  Bit Score: 219.25  E-value: 2.10e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30519919    37 NEKFICKLPDKGKKISDTVAKLKAAISEREEVRGRSELFHPVSVDCKLRQKATTrADTDVDKAQSSDLMLDTSSLDPDCS 116
Cdd:pfam15328  11 NKKFICKLPDKGKKILDFVEKLKAAIAEREEVERTAELLSPVNIDSKGKQKATA-LVLDSDKAQNSDQLLDTSSGTPHSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30519919   117 SIDIKSSKST-SETQGPTHLTHRGNEETLEAGYTVNSSPAAHIRARAPSSEVKEHLPQHSVSSQEEEISSSIDSLFITKL 195
Cdd:pfam15328  90 SVDVIKPSKTlSTQQDLAHIEEFGTEEAPESEYTVNKCPASSRASATSPSEASEILPQHGVSKQAEDLSSSSDNLLIDAL 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 30519919   196 QKITIADQSEP-SEENTSTENFPELQSETPKKPHYMKVLEMRARN 239
Cdd:pfam15328 170 QRITIADTEEHhSEENTSAEEKFGLRSGPPKKPHYMEVLEMRAKN 214
 
Name Accession Description Interval E-value
GCOM2 pfam15328
Putative GRINL1B complex locus protein 2; This protein family is named Putative GRINL1B ...
 37-239 2.10e-70

Putative GRINL1B complex locus protein 2; This protein family is named Putative GRINL1B complex locus protein 2. GRINL1B is short for: glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B. The name indicates what sort of receptor it is thought to be, a ligand gated ion channel specific to the neurotransmitter Glutamate. This family of proteins is found in eukaryotes. Proteins in this family are typically between 325 and 463 amino acids in length. The protein is thought to be the product of a pseudogene with a role in helping assemble a gene transcription unit.


Pssm-ID: 464649  Cd Length: 214  Bit Score: 219.25  E-value: 2.10e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30519919    37 NEKFICKLPDKGKKISDTVAKLKAAISEREEVRGRSELFHPVSVDCKLRQKATTrADTDVDKAQSSDLMLDTSSLDPDCS 116
Cdd:pfam15328  11 NKKFICKLPDKGKKILDFVEKLKAAIAEREEVERTAELLSPVNIDSKGKQKATA-LVLDSDKAQNSDQLLDTSSGTPHSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30519919   117 SIDIKSSKST-SETQGPTHLTHRGNEETLEAGYTVNSSPAAHIRARAPSSEVKEHLPQHSVSSQEEEISSSIDSLFITKL 195
Cdd:pfam15328  90 SVDVIKPSKTlSTQQDLAHIEEFGTEEAPESEYTVNKCPASSRASATSPSEASEILPQHGVSKQAEDLSSSSDNLLIDAL 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 30519919   196 QKITIADQSEP-SEENTSTENFPELQSETPKKPHYMKVLEMRARN 239
Cdd:pfam15328 170 QRITIADTEEHhSEENTSAEEKFGLRSGPPKKPHYMEVLEMRAKN 214
 
Name Accession Description Interval E-value
GCOM2 pfam15328
Putative GRINL1B complex locus protein 2; This protein family is named Putative GRINL1B ...
 37-239 2.10e-70

Putative GRINL1B complex locus protein 2; This protein family is named Putative GRINL1B complex locus protein 2. GRINL1B is short for: glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B. The name indicates what sort of receptor it is thought to be, a ligand gated ion channel specific to the neurotransmitter Glutamate. This family of proteins is found in eukaryotes. Proteins in this family are typically between 325 and 463 amino acids in length. The protein is thought to be the product of a pseudogene with a role in helping assemble a gene transcription unit.


Pssm-ID: 464649  Cd Length: 214  Bit Score: 219.25  E-value: 2.10e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30519919    37 NEKFICKLPDKGKKISDTVAKLKAAISEREEVRGRSELFHPVSVDCKLRQKATTrADTDVDKAQSSDLMLDTSSLDPDCS 116
Cdd:pfam15328  11 NKKFICKLPDKGKKILDFVEKLKAAIAEREEVERTAELLSPVNIDSKGKQKATA-LVLDSDKAQNSDQLLDTSSGTPHSS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30519919   117 SIDIKSSKST-SETQGPTHLTHRGNEETLEAGYTVNSSPAAHIRARAPSSEVKEHLPQHSVSSQEEEISSSIDSLFITKL 195
Cdd:pfam15328  90 SVDVIKPSKTlSTQQDLAHIEEFGTEEAPESEYTVNKCPASSRASATSPSEASEILPQHGVSKQAEDLSSSSDNLLIDAL 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 30519919   196 QKITIADQSEP-SEENTSTENFPELQSETPKKPHYMKVLEMRARN 239
Cdd:pfam15328 170 QRITIADTEEHhSEENTSAEEKFGLRSGPPKKPHYMEVLEMRAKN 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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