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Conserved domains on  [gi|1935010116|ref|NP_817091|]
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huntingtin-associated protein 1 isoform B [Rattus norvegicus]

Protein Classification

HAP1_N domain-containing protein( domain architecture ID 12058641)

HAP1_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 81-403 9.15e-119

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


:

Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 355.49  E-value: 9.15e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116  81 YIFQGPYGPRATGLGTGRAEGIWKTPAAYiGRRPGVSGPERAAFIRELQE--ALCPNPLPRKKITEDDIKVMLYLLEEKE 158
Cdd:pfam04849   1 EEQIPPYKLRADTLGTGYANQDWKIPSPA-GRPPEVSLPLSPEQIRETLNyfLLCSDRVSQMTKTYNDIEAVTRLLEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 159 RDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSdddeedeeDEEEEEGEEEEREG 238
Cdd:pfam04849  80 RDLELAARIGQSLLKQNSVLTERNEALEEQLGSAREEILQLRHELSKKDDLLQIYSND--------AEESETESSCSTPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 239 QRDQDQqhdhpygapkpppkaETLHHCPQLEALKQKLKLLEEENDHLREEASHL----DNLEDKEQMLILECVEQFSEAS 314
Cdd:pfam04849 152 RRNESF---------------SSLHGCVQLDALQEKLRGLEEENLKLRSEASHLktetDTYEEKEQQLMSDCVEQLSEAN 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 315 QQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQQLASEKGVHpESLRagSHMQDYGSRP---- 390
Cdd:pfam04849 217 QQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEELQQHLQASKEAQ-RQLT--SELQELQDRYaecl 293

                         330
                  ....*....|....*.
gi 1935010116 391 ---RERQEDGKSHRQR 403
Cdd:pfam04849 294 gmlHEAQEELKELRKK 309
 
Name Accession Description Interval E-value
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 81-403 9.15e-119

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 355.49  E-value: 9.15e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116  81 YIFQGPYGPRATGLGTGRAEGIWKTPAAYiGRRPGVSGPERAAFIRELQE--ALCPNPLPRKKITEDDIKVMLYLLEEKE 158
Cdd:pfam04849   1 EEQIPPYKLRADTLGTGYANQDWKIPSPA-GRPPEVSLPLSPEQIRETLNyfLLCSDRVSQMTKTYNDIEAVTRLLEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 159 RDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSdddeedeeDEEEEEGEEEEREG 238
Cdd:pfam04849  80 RDLELAARIGQSLLKQNSVLTERNEALEEQLGSAREEILQLRHELSKKDDLLQIYSND--------AEESETESSCSTPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 239 QRDQDQqhdhpygapkpppkaETLHHCPQLEALKQKLKLLEEENDHLREEASHL----DNLEDKEQMLILECVEQFSEAS 314
Cdd:pfam04849 152 RRNESF---------------SSLHGCVQLDALQEKLRGLEEENLKLRSEASHLktetDTYEEKEQQLMSDCVEQLSEAN 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 315 QQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQQLASEKGVHpESLRagSHMQDYGSRP---- 390
Cdd:pfam04849 217 QQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEELQQHLQASKEAQ-RQLT--SELQELQDRYaecl 293

                         330
                  ....*....|....*.
gi 1935010116 391 ---RERQEDGKSHRQR 403
Cdd:pfam04849 294 gmlHEAQEELKELRKK 309
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-369 6.74e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.55  E-value: 6.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 139 RKKITEDDIKVMLYLLEEKERDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDD 218
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 219 DEEDEEDEEEEEGEEEEREGQRDQDqqhdhpygapkpppkaetlhhcpQLEALKQKLKLLEEENDHLREEASHLDNLEDK 298
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEE-----------------------ELAELEEELEELEEELEELEEELEEAEEELEE 355

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1935010116 299 EQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQQLASE 369
Cdd:COG1196   356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 268-365 5.21e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 268 LEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITK 347
Cdd:TIGR04523 206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285

                          90
                  ....*....|....*...
gi 1935010116 348 LQQRCQSYGAQTEKLQQQ 365
Cdd:TIGR04523 286 LEKQLNQLKSEISDLNNQ 303
 
Name Accession Description Interval E-value
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 81-403 9.15e-119

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 355.49  E-value: 9.15e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116  81 YIFQGPYGPRATGLGTGRAEGIWKTPAAYiGRRPGVSGPERAAFIRELQE--ALCPNPLPRKKITEDDIKVMLYLLEEKE 158
Cdd:pfam04849   1 EEQIPPYKLRADTLGTGYANQDWKIPSPA-GRPPEVSLPLSPEQIRETLNyfLLCSDRVSQMTKTYNDIEAVTRLLEEKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 159 RDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSdddeedeeDEEEEEGEEEEREG 238
Cdd:pfam04849  80 RDLELAARIGQSLLKQNSVLTERNEALEEQLGSAREEILQLRHELSKKDDLLQIYSND--------AEESETESSCSTPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 239 QRDQDQqhdhpygapkpppkaETLHHCPQLEALKQKLKLLEEENDHLREEASHL----DNLEDKEQMLILECVEQFSEAS 314
Cdd:pfam04849 152 RRNESF---------------SSLHGCVQLDALQEKLRGLEEENLKLRSEASHLktetDTYEEKEQQLMSDCVEQLSEAN 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 315 QQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQQLASEKGVHpESLRagSHMQDYGSRP---- 390
Cdd:pfam04849 217 QQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEELQQHLQASKEAQ-RQLT--SELQELQDRYaecl 293

                         330
                  ....*....|....*.
gi 1935010116 391 ---RERQEDGKSHRQR 403
Cdd:pfam04849 294 gmlHEAQEELKELRKK 309
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-369 6.74e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.55  E-value: 6.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 139 RKKITEDDIKVMLYLLEEKERDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDD 218
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 219 DEEDEEDEEEEEGEEEEREGQRDQDqqhdhpygapkpppkaetlhhcpQLEALKQKLKLLEEENDHLREEASHLDNLEDK 298
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEE-----------------------ELAELEEELEELEEELEELEEELEEAEEELEE 355

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1935010116 299 EQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQQLASE 369
Cdd:COG1196   356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
267-370 1.86e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 267 QLEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLILECVEQFSEASQQMAELSEVLVLRL----EGYERQQKEITQLQ 342
Cdd:COG4717   133 ELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELqdlaEELEELQQRLAELE 212

                          90       100
                  ....*....|....*....|....*...
gi 1935010116 343 AEITKLQQRCQSYGAQTEKLQQQLASEK 370
Cdd:COG4717   213 EELEEAQEELEELEEELEQLENELEAAA 240
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
267-384 1.81e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116  267 QLEALKQKLKLLEEENDHLREEASHLDNL---------EDKEQM--LILECVEQFSEASQQMAELSEVLVLRLEGYERQQ 335
Cdd:COG4913    339 RLEQLEREIERLERELEERERRRARLEALlaalglplpASAEEFaaLRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1935010116  336 KEITQLQAEITKLQQRCQSYGAQTEKLQQQLASEKGVHPESLR-AGSHMQ 384
Cdd:COG4913    419 RELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELPfVGELIE 468
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 267-370 4.33e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 4.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 267 QLEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEIT 346
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100
                  ....*....|....*....|....
gi 1935010116 347 KLQQRCQSYGAQTEKLQQQLASEK 370
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELE 329
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 268-365 5.21e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 268 LEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITK 347
Cdd:TIGR04523 206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285

                          90
                  ....*....|....*...
gi 1935010116 348 LQQRCQSYGAQTEKLQQQ 365
Cdd:TIGR04523 286 LEKQLNQLKSEISDLNNQ 303
FlgN pfam05130
FlgN protein; This family includes the FlgN protein and export chaperone involved in flagellar ...
 267-353 8.12e-04

FlgN protein; This family includes the FlgN protein and export chaperone involved in flagellar synthesis.


Pssm-ID: 428323 [Multi-domain]  Cd Length: 140  Bit Score: 40.04  E-value: 8.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 267 QLEALKQKLKLLEEENDHLRE-EASHLDNLEDKEQmlilECVEQFSEASQQMAELSEVLVLRLEG--------YERQQKE 337
Cdd:pfam05130  10 ELELLEELLELLEEEQEALKAgDIEALEELTEEKQ----ELLQKLAQLEKERRELLAELGLSPEEatlsellaKEEEDPE 85

                          90
                  ....*....|....*.
gi 1935010116 338 ITQLQAEITKLQQRCQ 353
Cdd:pfam05130  86 LRELWQELLELLERLK 101
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
267-367 4.49e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 4.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 267 QLEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEIT 346
Cdd:COG4372    39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELE 118

                          90       100
                  ....*....|....*....|.
gi 1935010116 347 KLQQRCQSYGAQTEKLQQQLA 367
Cdd:COG4372   119 ELQKERQDLEQQRKQLEAQIA 139
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 267-348 7.34e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 7.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116  267 QLEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQ-QKEITQLQAEI 345
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEaRRRLKRLENKI 981


                   ...
gi 1935010116  346 TKL 348
Cdd:TIGR02168  982 KEL 984
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
267-370 7.78e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.12  E-value: 7.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116 267 QLEALKQKLKLLEEENDHLREEASHLDN-LEDKEQMLIlECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEI 345
Cdd:COG4372    46 ELEQLREELEQAREELEQLEEELEQARSeLEQLEEELE-ELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKER 124

                          90       100
                  ....*....|....*....|....*
gi 1935010116 346 TKLQQRCQSYGAQTEKLQQQLASEK 370
Cdd:COG4372   125 QDLEQQRKQLEAQIAELQSEIAERE 149
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
267-403 9.57e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 9.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935010116  267 QLEALKQKLKLLEEENDHLREEASHLDNLEDKEQMLI--LECVEQFSEASQQMAEL----SEVLVLRLEgYERQQKEITQ 340
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLdassDDLAALEEQ-LEELEAELEE 703

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1935010116  341 LQAEITKLQQRCQSYGAQTEKLQQQLASEKGVHPESLRAGSHMQDYGSRPRERQEDGKSHRQR 403
Cdd:COG4913    704 LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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